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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= I10A02NGRL0001_O24
         (378 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P49773 Cluster: Histidine triad nucleotide-binding prot...   188   3e-47
UniRef50_Q9BX68 Cluster: Histidine triad nucleotide-binding prot...   175   2e-43
UniRef50_Q8DK69 Cluster: Histidine triad nucleotide-binding prot...   157   5e-38
UniRef50_P32084 Cluster: Uncharacterized HIT-like protein Synpcc...   155   2e-37
UniRef50_P73481 Cluster: Uncharacterized HIT-like protein slr123...   151   4e-36
UniRef50_Q2F5W9 Cluster: Protein kinase C inhibitor; n=3; Endopt...   150   7e-36
UniRef50_P42856 Cluster: 14 kDa zinc-binding protein; n=11; Euka...   146   9e-35
UniRef50_UPI0000D555E3 Cluster: PREDICTED: similar to Hypothetic...   146   1e-34
UniRef50_A5GQU3 Cluster: HIT family hydrolase; n=10; Bacteria|Re...   139   1e-32
UniRef50_Q5TX49 Cluster: ENSANGP00000029056; n=1; Anopheles gamb...   139   2e-32
UniRef50_O66536 Cluster: Uncharacterized HIT-like protein aq_141...   136   1e-31
UniRef50_Q5K261 Cluster: Putative uncharacterized protein pkci; ...   134   7e-31
UniRef50_Q5R0G3 Cluster: HIT family hydrolase; n=20; Proteobacte...   132   2e-30
UniRef50_Q8F673 Cluster: HIT family hydrolase; n=6; cellular org...   130   8e-30
UniRef50_A6VZM3 Cluster: Histidine triad (HIT) protein; n=4; Pro...   129   1e-29
UniRef50_P0ACE9 Cluster: HIT-like protein ycfF; n=109; Bacteria|...   129   2e-29
UniRef50_A5K5T5 Cluster: Protein kinase C inhibitor, putative; n...   128   3e-29
UniRef50_A7H6R9 Cluster: Histidine triad (HIT) protein; n=14; Ba...   126   1e-28
UniRef50_UPI0000DBEF88 Cluster: UPI0000DBEF88 related cluster; n...   126   1e-28
UniRef50_Q5CSR7 Cluster: Histidine triad (HIT) family zinc bindi...   126   2e-28
UniRef50_Q7K6B1 Cluster: Protein kinase c inhibitor-like protein...   125   3e-28
UniRef50_Q892R5 Cluster: Hit family protein; n=16; Bacteria|Rep:...   124   4e-28
UniRef50_Q1YR93 Cluster: Protein kinase C inhibitor; n=2; Gammap...   124   5e-28
UniRef50_Q1CY35 Cluster: HIT domain protein; n=3; Bacteria|Rep: ...   123   1e-27
UniRef50_Q83DE2 Cluster: HIT family protein; n=24; Bacteria|Rep:...   122   2e-27
UniRef50_Q8KGB0 Cluster: HIT family protein; n=10; Bacteria|Rep:...   119   2e-26
UniRef50_A0BUI5 Cluster: Chromosome undetermined scaffold_129, w...   118   3e-26
UniRef50_Q3J6P8 Cluster: Histidine triad (HIT) protein; n=5; Pro...   116   1e-25
UniRef50_Q4JN62 Cluster: Predicted protein kinase C inhibitor ch...   114   4e-25
UniRef50_Q4N9V7 Cluster: Protein kinase C interacting protein 1,...   112   2e-24
UniRef50_Q182D4 Cluster: Histidine triad nucleotide-binding prot...   112   2e-24
UniRef50_A3EUM2 Cluster: Histidine triad protein; n=1; Leptospir...   109   2e-23
UniRef50_A7AQA5 Cluster: HIT domain containing protein; n=1; Bab...   109   2e-23
UniRef50_Q7W2X6 Cluster: MttA/Hcf106 family protein; n=30; Burkh...   107   5e-23
UniRef50_A6T373 Cluster: HIT family protein; n=20; Betaproteobac...   106   1e-22
UniRef50_O07817 Cluster: Protein hitA; n=7; Betaproteobacteria|R...   104   6e-22
UniRef50_A7A616 Cluster: Putative uncharacterized protein; n=2; ...   102   2e-21
UniRef50_Q93IL6 Cluster: Histidine nucleotide-binding protein; n...   102   3e-21
UniRef50_Q2LVF0 Cluster: Hit family hydrolase; n=1; Syntrophus a...   100   1e-20
UniRef50_A1SHY4 Cluster: Histidine triad (HIT) protein precursor...   100   2e-20
UniRef50_A0LCF6 Cluster: Histidine triad (HIT) protein; n=3; Bac...   100   2e-20
UniRef50_A4F9S9 Cluster: Protein kinase C inhibitor; n=3; Actino...    99   2e-20
UniRef50_A6WDH4 Cluster: Histidine triad (HIT) protein; n=2; Act...    99   3e-20
UniRef50_Q9SA09 Cluster: F28K20.9 protein; n=7; Magnoliophyta|Re...    99   3e-20
UniRef50_Q0BPX6 Cluster: Adenosine 5'-monophosphoramidase; n=7; ...    98   4e-20
UniRef50_A3DF72 Cluster: Histidine triad (HIT) protein; n=2; Clo...    98   4e-20
UniRef50_Q7M8Z0 Cluster: HIT-FAMILY PROTEIN; n=12; Epsilonproteo...    97   7e-20
UniRef50_Q8K9I9 Cluster: Uncharacterized HIT-like protein BUsg_3...    97   1e-19
UniRef50_A7H3E9 Cluster: HIT family protein; n=11; Campylobacter...    96   2e-19
UniRef50_Q9ZDL1 Cluster: Uncharacterized HIT-like protein RP317;...    95   4e-19
UniRef50_Q23921 Cluster: Protein pkiA; n=4; Dictyostelium discoi...    94   7e-19
UniRef50_Q5GT45 Cluster: HIT family hydrolase; n=4; Rickettsiale...    93   2e-18
UniRef50_A5CF29 Cluster: Protein kinase C inhibitor 1; n=1; Orie...    92   4e-18
UniRef50_P26724 Cluster: Uncharacterized 13.2 kDa HIT-like prote...    91   5e-18
UniRef50_Q0JIB7 Cluster: Os01g0813000 protein; n=3; Oryza sativa...    79   6e-18
UniRef50_Q8AYA7 Cluster: ASW-related protein; n=1; Taeniopygia g...    91   6e-18
UniRef50_A7HMY4 Cluster: Histidine triad (HIT) protein; n=2; The...    91   8e-18
UniRef50_A5IXY8 Cluster: HIT-like protein; n=1; Mycoplasma agala...    91   8e-18
UniRef50_Q9RTX9 Cluster: Hit family protein; n=2; Deinococcus|Re...    90   1e-17
UniRef50_Q9PK09 Cluster: Uncharacterized HIT-like protein TC_066...    90   1e-17
UniRef50_Q98RK0 Cluster: HIT-LIKE PROTEIN; n=2; Mycoplasma|Rep: ...    88   6e-17
UniRef50_A5BDT4 Cluster: Putative uncharacterized protein; n=2; ...    86   2e-16
UniRef50_Q6AEC2 Cluster: Putative uncharacterized protein; n=3; ...    83   1e-15
UniRef50_UPI000050FA96 Cluster: COG0537: Diadenosine tetraphosph...    81   7e-15
UniRef50_Q83MZ3 Cluster: HIT-like protein; n=2; Tropheryma whipp...    79   2e-14
UniRef50_P32083 Cluster: Uncharacterized 13.1 kDa HIT-like prote...    79   2e-14
UniRef50_Q9JN38 Cluster: Putative HIT-like protein; n=2; Mycopla...    79   3e-14
UniRef50_P64382 Cluster: Uncharacterized HIT-like protein HP_040...    79   4e-14
UniRef50_A6G534 Cluster: HIT-family protein; n=1; Plesiocystis p...    78   5e-14
UniRef50_Q1V185 Cluster: Histidine triad (HIT) protein; n=3; Bac...    78   6e-14
UniRef50_A5Z767 Cluster: Putative uncharacterized protein; n=1; ...    76   3e-13
UniRef50_Q74MW7 Cluster: NEQ519; n=1; Nanoarchaeum equitans|Rep:...    76   3e-13
UniRef50_A7D556 Cluster: Histidine triad (HIT) protein; n=1; Hal...    75   3e-13
UniRef50_Q58276 Cluster: Uncharacterized HIT-like protein MJ0866...    75   3e-13
UniRef50_Q970Y2 Cluster: 141aa long hypothetical histidine triad...    73   2e-12
UniRef50_Q8PVK5 Cluster: Hit-like protein; n=4; Methanosarcinace...    72   3e-12
UniRef50_Q1QBU6 Cluster: Histidine triad (HIT) protein; n=2; Psy...    71   7e-12
UniRef50_UPI00015C430C Cluster: HIT family protein; n=1; Strepto...    70   1e-11
UniRef50_Q8YHI2 Cluster: BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE; n=2...    70   1e-11
UniRef50_Q6A7Y9 Cluster: Putative cell-cycle regulation histidin...    69   2e-11
UniRef50_Q4L7E2 Cluster: Hit-like protein involved in cell-cycle...    69   2e-11
UniRef50_Q0LZX4 Cluster: Histidine triad (HIT) protein precursor...    69   4e-11
UniRef50_Q9A5H7 Cluster: HIT family protein; n=6; Alphaproteobac...    67   9e-11
UniRef50_Q6YPU5 Cluster: Diadenosine tetraphosphate hydrolase; n...    67   9e-11
UniRef50_Q5Z2D6 Cluster: Putative uncharacterized protein; n=1; ...    67   9e-11
UniRef50_Q03WU6 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    67   1e-10
UniRef50_Q5Z134 Cluster: Putative uncharacterized protein; n=1; ...    66   2e-10
UniRef50_Q8EW55 Cluster: Histidine triad protein HIT; n=1; Mycop...    66   2e-10
UniRef50_A0LM74 Cluster: Histidine triad (HIT) protein; n=1; Syn...    66   3e-10
UniRef50_Q89JY4 Cluster: Blr5135 protein; n=15; Alphaproteobacte...    65   5e-10
UniRef50_A5UPG3 Cluster: Histidine triad (HIT) protein; n=5; Chl...    64   6e-10
UniRef50_A1RYX9 Cluster: Histidine triad (HIT) protein; n=1; The...    64   8e-10
UniRef50_A4FZK6 Cluster: Histidine triad (HIT) protein; n=5; Met...    64   1e-09
UniRef50_A3HAI2 Cluster: Histidine triad (HIT) protein; n=2; The...    64   1e-09
UniRef50_Q74I95 Cluster: Hit protein; n=5; Lactobacillus|Rep: Hi...    63   1e-09
UniRef50_Q8ZTP1 Cluster: HIT family protein; n=4; Pyrobaculum|Re...    63   1e-09
UniRef50_Q672P8 Cluster: Histidine triad family protein precurso...    63   2e-09
UniRef50_Q88X03 Cluster: Cell-cycle regulation histidine triad p...    62   3e-09
UniRef50_Q6MTB0 Cluster: Histidine triad protein; n=2; Mycoplasm...    62   3e-09
UniRef50_Q4K6N7 Cluster: HIT family protein; n=1; Pseudomonas fl...    62   3e-09
UniRef50_A6FJ37 Cluster: Histidine triad (HIT) protein; n=1; Mor...    62   3e-09
UniRef50_P94252 Cluster: Uncharacterized HIT-like protein BB_037...    62   3e-09
UniRef50_Q39B39 Cluster: Histidine triad (HIT) protein; n=32; Pr...    62   3e-09
UniRef50_Q1NGF8 Cluster: HIT family protein; n=8; Proteobacteria...    62   3e-09
UniRef50_Q7R1Q2 Cluster: GLP_28_16821_16420; n=1; Giardia lambli...    62   3e-09
UniRef50_Q4DJ40 Cluster: Adenosine 5'-monophosphoramidase, putat...    62   3e-09
UniRef50_O07513 Cluster: Protein hit; n=16; Bacillaceae|Rep: Pro...    62   3e-09
UniRef50_Q6F1M1 Cluster: Putative nucleotidyl hydrolase/transfer...    62   4e-09
UniRef50_A1WAF8 Cluster: Histidine triad (HIT) protein; n=5; Bet...    62   4e-09
UniRef50_Q97S70 Cluster: HIT family protein; n=37; Streptococcac...    61   6e-09
UniRef50_Q1FG87 Cluster: Histidine triad (HIT) protein; n=5; Clo...    61   6e-09
UniRef50_A7R099 Cluster: Chromosome undetermined scaffold_300, w...    61   6e-09
UniRef50_A5EX58 Cluster: Histidine triad (HIT) domain protein; n...    61   8e-09
UniRef50_Q5UZ82 Cluster: Histidine triad protein; n=4; Halobacte...    61   8e-09
UniRef50_A4XT81 Cluster: Histidine triad (HIT) protein; n=7; Pse...    60   1e-08
UniRef50_Q9KDM3 Cluster: Hit-like protein involved in cell-cycle...    60   2e-08
UniRef50_Q3W573 Cluster: Histidine triad (HIT) protein; n=3; Act...    60   2e-08
UniRef50_Q0VNN6 Cluster: HIT family protein; n=1; Alcanivorax bo...    60   2e-08
UniRef50_Q7NAX8 Cluster: Hit-like; n=1; Mycoplasma gallisepticum...    59   2e-08
UniRef50_P75504 Cluster: Uncharacterized 16.1 kDa HIT-like prote...    59   2e-08
UniRef50_UPI00015B4104 Cluster: PREDICTED: hypothetical protein;...    58   5e-08
UniRef50_A6PM84 Cluster: Histidine triad (HIT) protein; n=1; Vic...    58   5e-08
UniRef50_Q023M8 Cluster: Histidine triad (HIT) protein; n=2; Bac...    58   7e-08
UniRef50_A6FN65 Cluster: HIT family protein; n=1; Roseobacter sp...    58   7e-08
UniRef50_P95937 Cluster: Uncharacterized HIT-like protein SSO216...    57   9e-08
UniRef50_Q11066 Cluster: Uncharacterized HIT-like protein Rv1262...    57   9e-08
UniRef50_UPI000155C234 Cluster: PREDICTED: similar to PKCI-Z-rel...    57   1e-07
UniRef50_A7BDL4 Cluster: Putative uncharacterized protein; n=1; ...    57   1e-07
UniRef50_A1VGI9 Cluster: Histidine triad (HIT) protein; n=2; Des...    57   1e-07
UniRef50_Q5KLA4 Cluster: Hydrolase, putative; n=2; Dikarya|Rep: ...    56   2e-07
UniRef50_P49774 Cluster: Uncharacterized HIT-like protein ML2237...    56   2e-07
UniRef50_A1G4L9 Cluster: Histidine triad (HIT) protein; n=3; Bac...    56   3e-07
UniRef50_A7SFV5 Cluster: Predicted protein; n=1; Nematostella ve...    56   3e-07
UniRef50_Q4LEG8 Cluster: Histidine triad protein; n=1; unculture...    56   3e-07
UniRef50_Q9V017 Cluster: Histidine triad (HIT) protein; n=4; The...    55   5e-07
UniRef50_UPI0000D55AC3 Cluster: PREDICTED: similar to histidine ...    54   7e-07
UniRef50_Q03D63 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    54   7e-07
UniRef50_Q7W2C9 Cluster: Histidine triad protein; n=4; Proteobac...    54   9e-07
UniRef50_A5KTI5 Cluster: Histidine triad (HIT) protein; n=1; can...    54   9e-07
UniRef50_Q04344 Cluster: Hit family protein 1; n=22; Dikarya|Rep...    54   9e-07
UniRef50_UPI000155CE00 Cluster: PREDICTED: similar to aprataxin;...    54   1e-06
UniRef50_Q1MR92 Cluster: 141aa long hypothetical histidine triad...    54   1e-06
UniRef50_Q64N76 Cluster: Histidine triad (HIT) family protein; n...    53   2e-06
UniRef50_Q31N56 Cluster: Putative uncharacterized protein; n=2; ...    53   2e-06
UniRef50_Q01IH1 Cluster: OSIGBa0159I10.14 protein; n=6; Magnolio...    53   2e-06
UniRef50_Q6L1V3 Cluster: Asymmetrical bis(5'-nucleosyl)-tetrapho...    53   2e-06
UniRef50_A4YEP9 Cluster: Histidine triad (HIT) protein; n=1; Met...    53   2e-06
UniRef50_Q67LQ3 Cluster: HIT family protein; n=1; Symbiobacteriu...    53   2e-06
UniRef50_A0RX45 Cluster: Asymmetrical bis(5'-nucleosyl)-tetrapho...    53   2e-06
UniRef50_A0RUN5 Cluster: Diadenosine tetraphosphate hydrolase; n...    53   2e-06
UniRef50_Q7Z2E3 Cluster: Aprataxin; n=44; Euteleostomi|Rep: Apra...    53   2e-06
UniRef50_Q65J74 Cluster: Putative uncharacterized protein; n=1; ...    52   3e-06
UniRef50_Q84VV6 Cluster: At4g16566; n=2; Arabidopsis thaliana|Re...    52   3e-06
UniRef50_Q702F5 Cluster: Putative HIT superfamily hydrolase; n=1...    52   3e-06
UniRef50_Q9PQL9 Cluster: Probable HIT protein; n=1; Ureaplasma p...    52   5e-06
UniRef50_Q2BQP2 Cluster: HIT domain protein; n=1; Neptuniibacter...    52   5e-06
UniRef50_Q5VQQ9 Cluster: Putative uncharacterized protein P0425G...    52   5e-06
UniRef50_A4AKY1 Cluster: Putative uncharacterized protein; n=1; ...    51   6e-06
UniRef50_A1SG63 Cluster: Histidine triad (HIT) protein; n=3; Act...    51   8e-06
UniRef50_A1AWF6 Cluster: Histidine triad (HIT) protein; n=1; Can...    51   8e-06
UniRef50_A0LI77 Cluster: Type III restriction enzyme, res subuni...    51   8e-06
UniRef50_P61799 Cluster: Aprataxin; n=21; Deuterostomia|Rep: Apr...    51   8e-06
UniRef50_UPI0000DB7407 Cluster: PREDICTED: similar to histidine ...    50   1e-05
UniRef50_Q4RFE2 Cluster: Chromosome 8 SCAF15119, whole genome sh...    50   1e-05
UniRef50_Q8FTW3 Cluster: Putative uncharacterized protein; n=1; ...    50   1e-05
UniRef50_A4BW57 Cluster: HIT family protein; n=14; Bacteroidetes...    50   1e-05
UniRef50_Q01D01 Cluster: Diadenosine tetraphosphate hydrolase; n...    50   1e-05
UniRef50_O76463 Cluster: Nitrilase and fragile histidine triad f...    50   1e-05
UniRef50_Q5WBH5 Cluster: Histidine triad protein involved in cel...    50   2e-05
UniRef50_A1VWA8 Cluster: Histidine triad (HIT) protein; n=5; cel...    50   2e-05
UniRef50_Q55V28 Cluster: Putative uncharacterized protein; n=1; ...    50   2e-05
UniRef50_UPI00003C03A1 Cluster: PREDICTED: similar to aprataxin;...    49   3e-05
UniRef50_A0W3X6 Cluster: Histidine triad (HIT) protein; n=3; Bac...    49   3e-05
UniRef50_UPI00015B4880 Cluster: PREDICTED: similar to FHA-HIT; n...    49   3e-05
UniRef50_UPI000038E073 Cluster: hypothetical protein Faci_030002...    49   3e-05
UniRef50_Q02WI9 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    49   3e-05
UniRef50_A7BYS1 Cluster: HIT family protein; n=2; Proteobacteria...    49   3e-05
UniRef50_Q4RR26 Cluster: Chromosome 14 SCAF15003, whole genome s...    48   4e-05
UniRef50_Q6NFF8 Cluster: HIT family protein; n=4; Corynebacteriu...    48   4e-05
UniRef50_UPI000050FB45 Cluster: COG0537: Diadenosine tetraphosph...    48   6e-05
UniRef50_A0YDE8 Cluster: Probable HIT family protein; n=1; marin...    48   8e-05
UniRef50_Q5DHH9 Cluster: SJCHGC02494 protein; n=1; Schistosoma j...    48   8e-05
UniRef50_UPI0000D55BA8 Cluster: PREDICTED: similar to aprataxin;...    47   1e-04
UniRef50_P61802 Cluster: Aprataxin; n=1; Ciona intestinalis|Rep:...    47   1e-04
UniRef50_UPI0000D55F17 Cluster: PREDICTED: similar to CG7067-PA;...    46   2e-04
UniRef50_Q9HIK0 Cluster: Cell-cycle regulation histidine triad (...    46   2e-04
UniRef50_Q4JA00 Cluster: HIT family protein; n=1; Sulfolobus aci...    46   2e-04
UniRef50_Q28BZ2 Cluster: Histidine triad nucleotide binding prot...    46   3e-04
UniRef50_Q8F4J7 Cluster: HIT family hydrolase; n=4; Leptospira|R...    46   3e-04
UniRef50_Q6SI40 Cluster: HIT family protein; n=1; uncultured bac...    46   3e-04
UniRef50_Q0UMA6 Cluster: Putative uncharacterized protein; n=1; ...    46   3e-04
UniRef50_Q727L0 Cluster: HIT family protein; n=2; Deltaproteobac...    45   4e-04
UniRef50_Q4SA00 Cluster: Chromosome undetermined SCAF14693, whol...    45   5e-04
UniRef50_A6S7H6 Cluster: Predicted protein; n=2; Sclerotiniaceae...    45   5e-04
UniRef50_P49776 Cluster: Bis(5'-nucleosyl)-tetraphosphatase [asy...    45   5e-04
UniRef50_Q7F2H9 Cluster: P0432B10.9 protein; n=8; Magnoliophyta|...    44   7e-04
UniRef50_Q2J8D3 Cluster: Histidine triad (HIT) protein; n=3; Fra...    44   0.001
UniRef50_Q5TVU2 Cluster: ENSANGP00000027488; n=1; Anopheles gamb...    44   0.001
UniRef50_Q3MMY7 Cluster: HINTW; n=4; Gallus gallus|Rep: HINTW - ...    44   0.001
UniRef50_A1CID8 Cluster: HIT domain protein; n=1; Aspergillus cl...    44   0.001
UniRef50_Q88TZ2 Cluster: Cell-cycle regulation histidine triad p...    43   0.002
UniRef50_Q9Y8Y9 Cluster: HIT family protein; n=1; Aeropyrum pern...    43   0.002
UniRef50_A2TZ69 Cluster: Putative cell-cycle regulation histidin...    43   0.002
UniRef50_Q4P3W7 Cluster: Putative uncharacterized protein; n=1; ...    43   0.002
UniRef50_Q979C0 Cluster: Histidine triad protein [HIT]; n=3; The...    43   0.002
UniRef50_Q7MKL5 Cluster: Diadenosine tetraphosphate hydrolase; n...    42   0.003
UniRef50_Q4FMD8 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    42   0.003
UniRef50_Q23FD8 Cluster: HIT domain containing protein; n=1; Tet...    42   0.003
UniRef50_Q7RY54 Cluster: Predicted protein; n=1; Neurospora cras...    42   0.004
UniRef50_A1C6L1 Cluster: HIT domain protein; n=9; Pezizomycotina...    42   0.004
UniRef50_Q8FML1 Cluster: Putative uncharacterized protein; n=2; ...    42   0.005
UniRef50_Q28QE4 Cluster: Histidine triad (HIT) protein; n=1; Jan...    42   0.005
UniRef50_Q57WA7 Cluster: Putative uncharacterized protein; n=1; ...    42   0.005
UniRef50_A7FTJ1 Cluster: HIT family protein; n=4; Clostridium bo...    41   0.007
UniRef50_Q558W0 Cluster: Putative uncharacterized protein; n=3; ...    41   0.007
UniRef50_Q4MZI5 Cluster: Bis(5'-nucleosyl)-tetraphosphatase (Asy...    41   0.007
UniRef50_A6QVS2 Cluster: Predicted protein; n=1; Ajellomyces cap...    41   0.007
UniRef50_A1RXN8 Cluster: Histidine triad (HIT) protein; n=1; The...    41   0.007
UniRef50_Q7MA74 Cluster: HIT FAMILY PROTEIN; n=3; Helicobacterac...    41   0.009
UniRef50_A7HHG6 Cluster: Type III restriction protein res subuni...    41   0.009
UniRef50_Q8SR62 Cluster: BIS 5'-ADENOSYL TRIPHOSPHATASE OF THE H...    41   0.009
UniRef50_A3CVL7 Cluster: Histidine triad (HIT) protein; n=1; Met...    40   0.012
UniRef50_P49775 Cluster: Hit family protein 2; n=2; Saccharomyce...    40   0.012
UniRef50_Q3MMY8 Cluster: HINTW; n=5; Phasianidae|Rep: HINTW - Ph...    40   0.015
UniRef50_Q97IN2 Cluster: HIT family hydrolase; n=4; Bacteria|Rep...    40   0.015
UniRef50_Q9NQE9 Cluster: Histidine triad nucleotide binding prot...    40   0.015
UniRef50_Q8SRE4 Cluster: HIT FAMILY PROTEIN; n=1; Encephalitozoo...    40   0.015
UniRef50_A7I5E0 Cluster: Histidine triad (HIT) protein; n=1; Can...    40   0.015
UniRef50_Q9IB93 Cluster: Wpkci; n=20; Neognathae|Rep: Wpkci - Co...    40   0.020
UniRef50_Q0V966 Cluster: Zgc:136256; n=4; Danio rerio|Rep: Zgc:1...    40   0.020
UniRef50_Q2BE03 Cluster: Cell-cycle regulation histidine triad, ...    40   0.020
UniRef50_A3ESI2 Cluster: Diadenosine tetraphosphate hydrolase; n...    40   0.020
UniRef50_Q17CS4 Cluster: Nitrilase, putative; n=3; Culicidae|Rep...    40   0.020
UniRef50_A2E0S0 Cluster: HIT domain containing protein; n=1; Tri...    40   0.020
UniRef50_A4RGB9 Cluster: Putative uncharacterized protein; n=1; ...    40   0.020
UniRef50_Q74ND2 Cluster: NEQ213; n=1; Nanoarchaeum equitans|Rep:...    40   0.020
UniRef50_A0B7E7 Cluster: Histidine triad (HIT) protein; n=1; Met...    40   0.020
UniRef50_Q6F6S5 Cluster: Putative histidine triad family protein...    39   0.027
UniRef50_A6G0U4 Cluster: Helicase, DEAD/DEAH family protein; n=1...    39   0.027
UniRef50_A3Z7E0 Cluster: HIT family protein; n=6; Synechococcus|...    39   0.027
UniRef50_A1UF80 Cluster: Histidine triad (HIT) protein; n=5; Myc...    39   0.027
UniRef50_Q54DF5 Cluster: Putative uncharacterized protein; n=1; ...    39   0.027
UniRef50_Q18227 Cluster: Putative uncharacterized protein; n=2; ...    39   0.027
UniRef50_Q8EIE9 Cluster: Putative uncharacterized protein; n=1; ...    39   0.035
UniRef50_Q0IT83 Cluster: Os11g0295000 protein; n=2; Oryza sativa...    39   0.035
UniRef50_Q4PA08 Cluster: Putative uncharacterized protein; n=1; ...    39   0.035
UniRef50_A2Q8C2 Cluster: Similarity: the HIT; n=1; Aspergillus n...    39   0.035
UniRef50_Q9JIX3 Cluster: Bis(5'-adenosyl)-triphosphatase; n=11; ...    39   0.035
UniRef50_P49789 Cluster: Bis(5'-adenosyl)-triphosphatase; n=31; ...    38   0.047
UniRef50_UPI00006CEB92 Cluster: HIT domain containing protein; n...    38   0.062
UniRef50_A6DMK8 Cluster: Hit-like protein; n=1; Lentisphaera ara...    38   0.082
UniRef50_A4J7H7 Cluster: Histidine triad (HIT) protein; n=4; cel...    38   0.082
UniRef50_A3M5B1 Cluster: Putative histidine triad family protein...    38   0.082
UniRef50_Q16YN6 Cluster: Protein kinase C inhibitor, putative; n...    38   0.082
UniRef50_A7E9D7 Cluster: Putative uncharacterized protein; n=1; ...    38   0.082
UniRef50_A3LQ09 Cluster: Diadenosine polyphosphate hydrolase; n=...    38   0.082
UniRef50_A3HA11 Cluster: Histidine triad (HIT) protein; n=1; Cal...    38   0.082
UniRef50_A6DCA2 Cluster: Histidine triad (HIT) protein; n=1; Cam...    37   0.11 
UniRef50_A7QKZ8 Cluster: Chromosome chr8 scaffold_115, whole gen...    37   0.11 
UniRef50_Q7PTZ0 Cluster: ENSANGP00000012901; n=2; Anopheles gamb...    37   0.14 
UniRef50_A7AWZ4 Cluster: Bis(5'-adenosyl)-triphosphatase, putati...    37   0.14 
UniRef50_Q55W99 Cluster: Putative uncharacterized protein; n=2; ...    37   0.14 
UniRef50_Q8MSG8 Cluster: Aprataxin-like protein; n=6; Sophophora...    37   0.14 
UniRef50_Q8YU88 Cluster: All2466 protein; n=5; Cyanobacteria|Rep...    36   0.19 
UniRef50_Q8D5M0 Cluster: Diadenosine tetraphosphate hydrolase; n...    36   0.19 
UniRef50_Q6AQ03 Cluster: Putative uncharacterized protein; n=1; ...    36   0.19 
UniRef50_A5I340 Cluster: Hit family protein; n=4; Clostridium bo...    36   0.19 
UniRef50_Q4FXZ6 Cluster: Putative uncharacterized protein; n=5; ...    36   0.19 
UniRef50_A2R633 Cluster: Contig An15c0220, complete genome; n=3;...    36   0.19 
UniRef50_Q6MQA8 Cluster: HIT family hydrolases; n=1; Bdellovibri...    36   0.33 
UniRef50_A5CMM3 Cluster: Putative diadenosine tetraphosphate (Ap...    36   0.33 
UniRef50_Q4XMZ5 Cluster: Histidine triad protein, putative; n=5;...    36   0.33 
UniRef50_Q75EY1 Cluster: AAL053Cp; n=3; Saccharomycetaceae|Rep: ...    36   0.33 
UniRef50_Q4RGE9 Cluster: Chromosome 18 SCAF15100, whole genome s...    35   0.44 
UniRef50_Q1Q3B4 Cluster: Putative uncharacterized protein; n=1; ...    35   0.44 
UniRef50_Q1IHJ0 Cluster: Histidine triad (HIT) protein; n=3; Aci...    35   0.58 
UniRef50_Q10MW4 Cluster: Basic helix-loop-helix, putative, expre...    35   0.58 
UniRef50_Q5B6X2 Cluster: Putative uncharacterized protein; n=2; ...    35   0.58 
UniRef50_A5AAJ4 Cluster: Putative uncharacterized protein; n=1; ...    35   0.58 
UniRef50_Q4JAT6 Cluster: HIT family protein; n=7; cellular organ...    35   0.58 
UniRef50_O67912 Cluster: Putative uncharacterized protein; n=1; ...    34   0.76 
UniRef50_Q1ITK1 Cluster: Transcriptional regulator, CadC; n=1; A...    34   0.76 
UniRef50_Q6I3E1 Cluster: HIT family protein; n=9; Bacillus cereu...    34   1.0  
UniRef50_A2Q9C6 Cluster: Similarities; n=4; Pezizomycotina|Rep: ...    34   1.0  
UniRef50_Q2S3N3 Cluster: HIT domain protein; n=1; Salinibacter r...    33   1.3  
UniRef50_A7CXN8 Cluster: Histidine triad (HIT) protein; n=1; Opi...    33   1.3  
UniRef50_Q6IIA4 Cluster: HDC19222; n=1; Drosophila melanogaster|...    33   1.3  
UniRef50_Q6MP02 Cluster: Hit family hydrolase; n=1; Bdellovibrio...    33   1.8  
UniRef50_Q6C515 Cluster: Similar to tr|Q08702 Saccharomyces cere...    33   1.8  
UniRef50_Q2UDG1 Cluster: Predicted hydrolase; n=8; Eurotiomyceti...    33   1.8  
UniRef50_Q1MRT3 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    33   2.3  
UniRef50_A5KT99 Cluster: Histidine triad (HIT) protein; n=2; can...    33   2.3  
UniRef50_A3MA76 Cluster: Putative histidine triad family protein...    33   2.3  
UniRef50_A0DVG5 Cluster: Chromosome undetermined scaffold_66, wh...    33   2.3  
UniRef50_Q2GQK9 Cluster: Putative uncharacterized protein; n=1; ...    33   2.3  
UniRef50_A2QJY0 Cluster: Contig An04c0280, complete genome; n=2;...    33   2.3  
UniRef50_Q1IUV2 Cluster: Galactose-1-phosphate uridylyltransfera...    32   3.1  
UniRef50_UPI0000E47ACB Cluster: PREDICTED: hypothetical protein,...    32   4.1  
UniRef50_A2AT18 Cluster: Titin; n=11; Eukaryota|Rep: Titin - Mus...    32   4.1  
UniRef50_A7HCP6 Cluster: Histidine triad (HIT) protein; n=2; Ana...    32   4.1  
UniRef50_A1R1W7 Cluster: Putative histidine triad protein; n=1; ...    32   4.1  
UniRef50_Q0IQH7 Cluster: Os12g0120400 protein; n=1; Oryza sativa...    32   4.1  
UniRef50_Q6FTA1 Cluster: Similar to sp|P49775 Saccharomyces cere...    32   4.1  
UniRef50_Q6C837 Cluster: Similar to tr|Q9HFN0 Emericella nidulan...    32   4.1  
UniRef50_A6SGE0 Cluster: Putative uncharacterized protein; n=1; ...    32   4.1  
UniRef50_O76464 Cluster: Nitrilase and fragile histidine triad f...    32   4.1  
UniRef50_Q2LT70 Cluster: Hypothetical cytosolic protein; n=1; Sy...    31   5.4  
UniRef50_A6Q3Z1 Cluster: Histidine triad family protein; n=16; E...    31   5.4  
UniRef50_Q0UDM3 Cluster: Putative uncharacterized protein; n=1; ...    31   5.4  
UniRef50_A1CTB8 Cluster: GINS DNA replication complex subunit Sl...    31   5.4  
UniRef50_Q10422 Cluster: Uncharacterized RNA-binding protein C25...    31   5.4  
UniRef50_Q3E2Z6 Cluster: Histidine triad (HIT) protein; n=7; cel...    31   7.1  
UniRef50_Q15XH7 Cluster: Putative uncharacterized protein precur...    31   7.1  
UniRef50_Q0A9K4 Cluster: Sel1 domain protein repeat-containing p...    31   7.1  
UniRef50_Q021F5 Cluster: Putative cell-cycle regulation histidin...    31   7.1  
UniRef50_Q6K6S3 Cluster: Putative uncharacterized protein P0040H...    31   7.1  
UniRef50_Q7KU09 Cluster: CG31666-PB, isoform B; n=4; Sophophora|...    31   7.1  
UniRef50_P0C091 Cluster: FRAS1-related extracellular matrix prot...    31   7.1  
UniRef50_UPI0000F2DD70 Cluster: PREDICTED: similar to Fhit prote...    31   9.4  
UniRef50_UPI0000E49E74 Cluster: PREDICTED: hypothetical protein;...    31   9.4  
UniRef50_Q4SR64 Cluster: Chromosome 11 SCAF14528, whole genome s...    31   9.4  
UniRef50_Q8DTJ5 Cluster: Putative bacitracin synthetase 1; BacA;...    31   9.4  
UniRef50_A5UZX9 Cluster: Galactose-1-phosphate uridylyltransfera...    31   9.4  
UniRef50_A1ZPF4 Cluster: Sensor protein; n=1; Microscilla marina...    31   9.4  
UniRef50_A1VUA8 Cluster: Putative uncharacterized protein; n=1; ...    31   9.4  
UniRef50_Q57W75 Cluster: Bis(5'-adenosyl)-triphosphatase, putati...    31   9.4  
UniRef50_Q4WTN7 Cluster: Nucleosome assembly protein Nap1, putat...    31   9.4  
UniRef50_Q2H0I6 Cluster: Putative uncharacterized protein; n=1; ...    31   9.4  
UniRef50_A6SIL7 Cluster: Putative uncharacterized protein; n=1; ...    31   9.4  
UniRef50_A4RHH5 Cluster: Putative uncharacterized protein; n=1; ...    31   9.4  
UniRef50_P52945 Cluster: Pancreas/duodenum homeobox protein 1; n...    31   9.4  

>UniRef50_P49773 Cluster: Histidine triad nucleotide-binding protein
           1; n=46; cellular organisms|Rep: Histidine triad
           nucleotide-binding protein 1 - Homo sapiens (Human)
          Length = 126

 Score =  188 bits (458), Expect = 3e-47
 Identities = 81/123 (65%), Positives = 104/123 (84%)
 Frame = +2

Query: 8   EVELAKSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQL 187
           E+  A+ A PGGDTIFGKI+RKEIPAK ++EDD+C+AFHD++PQAPTH LVIP+K ISQ+
Sbjct: 4   EIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQI 63

Query: 188 SKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLE 367
           S A D+DE LLGHL+IV +K A   GL+K G+R+V+N+G +G QSVYH+H+HVLGGRQ+ 
Sbjct: 64  SVAEDDDESLLGHLMIVGKKCAADLGLNK-GYRMVVNEGSDGGQSVYHVHLHVLGGRQMH 122

Query: 368 WPP 376
           WPP
Sbjct: 123 WPP 125


>UniRef50_Q9BX68 Cluster: Histidine triad nucleotide-binding protein
           2; n=61; cellular organisms|Rep: Histidine triad
           nucleotide-binding protein 2 - Homo sapiens (Human)
          Length = 163

 Score =  175 bits (427), Expect = 2e-43
 Identities = 82/127 (64%), Positives = 99/127 (77%), Gaps = 2/127 (1%)
 Frame = +2

Query: 2   GGEVELAKSAAPGG--DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKP 175
           G EV  A+ A PGG   TIF +IL K +PA  +YED QC+ F DV PQAP H LVIP+KP
Sbjct: 37  GNEVAKAQQATPGGAAPTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKP 96

Query: 176 ISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGG 355
           I ++S+A +ED+QLLGHLL+VA++ A  EGL   G+RLVINDGK GAQSVYHLH+HVLGG
Sbjct: 97  IPRISQAEEEDQQLLGHLLLVAKQTAKAEGLG-DGYRLVINDGKLGAQSVYHLHIHVLGG 155

Query: 356 RQLEWPP 376
           RQL+WPP
Sbjct: 156 RQLQWPP 162


>UniRef50_Q8DK69 Cluster: Histidine triad nucleotide-binding
           protein; n=15; Bacteria|Rep: Histidine triad
           nucleotide-binding protein - Synechococcus elongatus
           (Thermosynechococcus elongatus)
          Length = 114

 Score =  157 bits (382), Expect = 5e-38
 Identities = 67/111 (60%), Positives = 92/111 (82%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           +TIF +I+R+EIPA  V+ED+ C+AF D+NPQAP HILVIP+KPI QLS A  ED ++LG
Sbjct: 4   ETIFSRIIRREIPADIVHEDELCLAFRDINPQAPVHILVIPKKPIPQLSLAEPEDHRVLG 63

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           HLL+ A+++A  EGL  +G+R+VIN+G +G Q+VYHLH+H+LGGR ++WPP
Sbjct: 64  HLLLTAKRIAEAEGL-TNGYRVVINNGPDGGQTVYHLHLHLLGGRPMQWPP 113


>UniRef50_P32084 Cluster: Uncharacterized HIT-like protein
           Synpcc7942_1390; n=22; cellular organisms|Rep:
           Uncharacterized HIT-like protein Synpcc7942_1390 -
           Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
           R2)
          Length = 114

 Score =  155 bits (377), Expect = 2e-37
 Identities = 70/111 (63%), Positives = 86/111 (77%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           DTIFGKI+R+EIPA  VYEDD C+AF DV PQAP HILVIP++PI+ L +A  E + LLG
Sbjct: 4   DTIFGKIIRREIPADIVYEDDLCLAFRDVAPQAPVHILVIPKQPIANLLEATAEHQALLG 63

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           HLL+  + +A QEGL + G+R VIN G  G Q+VYHLH+H+LGGR L WPP
Sbjct: 64  HLLLTVKAIAAQEGLTE-GYRTVINTGPAGGQTVYHLHIHLLGGRSLAWPP 113


>UniRef50_P73481 Cluster: Uncharacterized HIT-like protein slr1234;
           n=8; cellular organisms|Rep: Uncharacterized HIT-like
           protein slr1234 - Synechocystis sp. (strain PCC 6803)
          Length = 114

 Score =  151 bits (366), Expect = 4e-36
 Identities = 68/111 (61%), Positives = 84/111 (75%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           DTIF KI+R+EIPA  VYEDD C+AF DVNPQAP H+L+IP+KP+ QLS A  ED  LLG
Sbjct: 4   DTIFSKIIRREIPAAIVYEDDLCLAFKDVNPQAPVHVLLIPKKPLPQLSAATPEDHALLG 63

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           HLL+ A++VA   G+    FRLVIN+G    Q+V+HLH+H+LGGR   WPP
Sbjct: 64  HLLLKAKEVAADLGIGDQ-FRLVINNGAEVGQTVFHLHLHILGGRPFSWPP 113


>UniRef50_Q2F5W9 Cluster: Protein kinase C inhibitor; n=3;
           Endopterygota|Rep: Protein kinase C inhibitor - Bombyx
           mori (Silk moth)
          Length = 162

 Score =  150 bits (364), Expect = 7e-36
 Identities = 67/112 (59%), Positives = 87/112 (77%)
 Frame = +2

Query: 41  GDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLL 220
           G TIF KI+ KEI A  +YEDD C+AF+D+ PQAP H LVIP++ I++L  A + D +LL
Sbjct: 52  GPTIFDKIISKEIRADIIYEDDLCLAFNDIAPQAPVHFLVIPKRRIARLQDAENNDNELL 111

Query: 221 GHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           GHL++VAR +  Q     SG+RLV+N+GK+GAQSVYHLH+HVLGGRQ+ WPP
Sbjct: 112 GHLMLVARSLGAQRA--PSGWRLVVNNGKDGAQSVYHLHLHVLGGRQMGWPP 161


>UniRef50_P42856 Cluster: 14 kDa zinc-binding protein; n=11;
           Eukaryota|Rep: 14 kDa zinc-binding protein - Zea mays
           (Maize)
          Length = 128

 Score =  147 bits (355), Expect = 9e-35
 Identities = 69/125 (55%), Positives = 93/125 (74%), Gaps = 2/125 (1%)
 Frame = +2

Query: 8   EVELAKSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIP--RKPIS 181
           E E A        TIF KI++KEIP+  VYED++ +AF D+NPQAPTHIL+IP  +  ++
Sbjct: 4   EKEAALRRLDDSPTIFDKIIKKEIPSTVVYEDEKVLAFRDINPQAPTHILIIPKVKDGLT 63

Query: 182 QLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQ 361
            L+KA +   ++LG+LL VA+ VA QEGL+  G+R+VINDG +G QSVYH+HVH+LGGRQ
Sbjct: 64  GLAKAEERHIEILGYLLYVAKVVAKQEGLE-DGYRVVINDGPSGCQSVYHIHVHLLGGRQ 122

Query: 362 LEWPP 376
           + WPP
Sbjct: 123 MNWPP 127


>UniRef50_UPI0000D555E3 Cluster: PREDICTED: similar to Hypothetical
           HIT-like protein F21C3.3; n=3; Coelomata|Rep: PREDICTED:
           similar to Hypothetical HIT-like protein F21C3.3 -
           Tribolium castaneum
          Length = 156

 Score =  146 bits (354), Expect = 1e-34
 Identities = 70/125 (56%), Positives = 93/125 (74%), Gaps = 2/125 (1%)
 Frame = +2

Query: 8   EVELAKSAAPGGD--TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPIS 181
           EVE A++A+      TIF KI+ KEIPA  +YEDD+C+AF+DVNPQAP H LVIP++ I 
Sbjct: 33  EVEKAQTASKDKQQTTIFDKIISKEIPADIIYEDDKCLAFNDVNPQAPVHFLVIPKQRIP 92

Query: 182 QLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQ 361
            L    D D+ ++  L++ A+K+A +E L  +G+RLVIN+GK G QSVYHLH+H+LGGRQ
Sbjct: 93  MLDSVKDSDKDIMAELVLRAQKLA-KERL-PNGYRLVINNGKQGCQSVYHLHIHILGGRQ 150

Query: 362 LEWPP 376
           L WPP
Sbjct: 151 LGWPP 155


>UniRef50_A5GQU3 Cluster: HIT family hydrolase; n=10; Bacteria|Rep:
           HIT family hydrolase - Synechococcus sp. (strain RCC307)
          Length = 234

 Score =  139 bits (337), Expect = 1e-32
 Identities = 65/115 (56%), Positives = 81/115 (70%)
 Frame = +2

Query: 32  APGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDE 211
           A    TIFG+ILR EIPA+ ++ED+ C+AF D+ PQAP H+LVIPR+ I  L +A   D 
Sbjct: 121 AENNPTIFGRILRGEIPAERIHEDEHCIAFADIQPQAPVHLLVIPRQHIPSLKEAQPSDS 180

Query: 212 QLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
            LLGHLL+VA KVA + GL    +R VIN G    Q+V+HLHVHV+GGR L WPP
Sbjct: 181 ALLGHLLLVAAKVAKEAGL--QDWRTVINTGAEAGQTVFHLHVHVIGGRPLAWPP 233


>UniRef50_Q5TX49 Cluster: ENSANGP00000029056; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000029056 - Anopheles gambiae
           str. PEST
          Length = 153

 Score =  139 bits (336), Expect = 2e-32
 Identities = 62/118 (52%), Positives = 83/118 (70%)
 Frame = +2

Query: 23  KSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGD 202
           K      DTIF KI++K+IPA  +YED++C+AF+DV PQAP H LVIP+  I +L  +  
Sbjct: 37  KPGVANPDTIFDKIIKKQIPADVIYEDEKCIAFNDVAPQAPVHFLVIPKNKIDKLENSTP 96

Query: 203 EDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
              +LLGHLL VA ++   +     GFRLVIN+G +G Q+VYH+H+HV+GGRQL WPP
Sbjct: 97  NQTELLGHLLHVAGQLGKSKA--PKGFRLVINNGDHGCQTVYHIHLHVIGGRQLGWPP 152


>UniRef50_O66536 Cluster: Uncharacterized HIT-like protein aq_141;
           n=9; Bacteria|Rep: Uncharacterized HIT-like protein
           aq_141 - Aquifex aeolicus
          Length = 121

 Score =  136 bits (330), Expect = 1e-31
 Identities = 63/116 (54%), Positives = 85/116 (73%), Gaps = 5/116 (4%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI+R E+PAK VYEDD+ +AFHD+NP AP HIL+IP+K I  +     EDE L+G
Sbjct: 5   DCIFCKIVRGEVPAKKVYEDDKVLAFHDINPVAPVHILIIPKKHIMGIQTLEPEDECLVG 64

Query: 224 HLLIVARKVATQEGL--DKS---GFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           H+  VARK+A   G+  D++   G+RLV N GK+  QSV+HLH+H++GGR++ WPP
Sbjct: 65  HMFYVARKIAEDLGIAPDENLNKGYRLVFNVGKDAGQSVFHLHLHLIGGREMSWPP 120


>UniRef50_Q5K261 Cluster: Putative uncharacterized protein pkci;
           n=3; cellular organisms|Rep: Putative uncharacterized
           protein pkci - Guillardia theta (Cryptomonas phi)
          Length = 181

 Score =  134 bits (323), Expect = 7e-31
 Identities = 63/112 (56%), Positives = 82/112 (73%), Gaps = 2/112 (1%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIP--RKPISQLSKAGDEDEQLL 220
           TIF KI+ K IP++ V+EDD+ + F D+NPQAPTH+LVIP  R+ +SQL  A  E E +L
Sbjct: 71  TIFDKIVAKSIPSQVVFEDDKVLVFKDINPQAPTHLLVIPKRRETLSQLRFATAEHEGIL 130

Query: 221 GHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           GH+L V  KVA++EGL    +RLV+NDG+   Q V+HLH+HVL GR L WPP
Sbjct: 131 GHMLAVVAKVASEEGL--GDYRLVVNDGRGAGQEVFHLHMHVLAGRPLTWPP 180


>UniRef50_Q5R0G3 Cluster: HIT family hydrolase; n=20;
           Proteobacteria|Rep: HIT family hydrolase - Idiomarina
           loihiensis
          Length = 122

 Score =  132 bits (320), Expect = 2e-30
 Identities = 52/111 (46%), Positives = 82/111 (73%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           +TIF KI+ ++IPA  +YEDD+ +AF D+NPQAP H L+IP++PI+  +   +++  L+G
Sbjct: 4   ETIFTKIINRDIPADIIYEDDKALAFKDINPQAPFHCLIIPKQPIATANDINEDNAGLVG 63

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           HL +VA K+A +    + G+RLV+N  + G Q+VYH+H+H+L G+Q+ WPP
Sbjct: 64  HLYVVAAKLAAEHNFSQDGYRLVMNCNEYGGQTVYHIHLHMLAGKQMGWPP 114


>UniRef50_Q8F673 Cluster: HIT family hydrolase; n=6; cellular
           organisms|Rep: HIT family hydrolase - Leptospira
           interrogans
          Length = 122

 Score =  130 bits (314), Expect = 8e-30
 Identities = 56/109 (51%), Positives = 81/109 (74%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI+RKEIP+K V+E+D+ +AF+D++PQAP HI+ IP+K I  LS+  +ED  LLG++
Sbjct: 13  IFCKIIRKEIPSKVVFENDEILAFYDISPQAPVHIVFIPKKHIPSLSEIENEDSHLLGNI 72

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           L+  R  A   G  ++G+R+V N GKNG Q+V+H+H H+L  R+L WPP
Sbjct: 73  LLQIRDTAKNLGFAENGYRVVNNTGKNGGQTVFHIHFHLLAERRLHWPP 121


>UniRef50_A6VZM3 Cluster: Histidine triad (HIT) protein; n=4;
           Proteobacteria|Rep: Histidine triad (HIT) protein -
           Marinomonas sp. MWYL1
          Length = 113

 Score =  129 bits (312), Expect = 1e-29
 Identities = 54/111 (48%), Positives = 80/111 (72%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F KI++ +IPA  ++EDD  +AF D+ P+APTH LVIP++ IS L+   DED  ++G
Sbjct: 2   DCLFCKIVKGDIPANILFEDDDVIAFEDIMPKAPTHFLVIPKRHISTLNDLTDEDAPVVG 61

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
            L   A K+A Q+G+  +G+R+V+N  + G Q+VYH+H+HVLGGR + WPP
Sbjct: 62  KLQTTAAKIAKQKGISNAGYRVVMNCNEMGGQTVYHIHMHVLGGRAMTWPP 112


>UniRef50_P0ACE9 Cluster: HIT-like protein ycfF; n=109;
           Bacteria|Rep: HIT-like protein ycfF - Shigella flexneri
          Length = 119

 Score =  129 bits (311), Expect = 2e-29
 Identities = 55/107 (51%), Positives = 78/107 (72%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           +TIF KI+R+EIP+  VY+DD   AF D++PQAPTHIL+IP   I  ++    E EQ LG
Sbjct: 4   ETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVSAEHEQALG 63

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
            ++ VA K+A QEG+ + G+RL++N  ++G Q VYH+H+H+LGGR L
Sbjct: 64  RMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGRPL 110


>UniRef50_A5K5T5 Cluster: Protein kinase C inhibitor, putative; n=5;
           cellular organisms|Rep: Protein kinase C inhibitor,
           putative - Plasmodium vivax
          Length = 185

 Score =  128 bits (309), Expect = 3e-29
 Identities = 62/128 (48%), Positives = 88/128 (68%), Gaps = 5/128 (3%)
 Frame = +2

Query: 8   EVELAKSAA---PGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIP--RK 172
           E E A +AA     GD+IFGKI RKE+    VYEDD+ +AF+D+NPQAP HILVIP  R 
Sbjct: 59  EEEKALAAAGKDENGDSIFGKIARKEVKVDLVYEDDKVLAFNDINPQAPVHILVIPKMRD 118

Query: 173 PISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLG 352
            +++LSKA +  +++LGH++    ++  +  L    FRLV+N+G    QSVY+LH+H+L 
Sbjct: 119 GLTRLSKAEERHKEILGHMMWAVSEIVKKNNL--GDFRLVVNNGPEACQSVYYLHLHILA 176

Query: 353 GRQLEWPP 376
            RQ++WPP
Sbjct: 177 KRQMKWPP 184


>UniRef50_A7H6R9 Cluster: Histidine triad (HIT) protein; n=14;
           Bacteria|Rep: Histidine triad (HIT) protein -
           Anaeromyxobacter sp. Fw109-5
          Length = 114

 Score =  126 bits (305), Expect = 1e-28
 Identities = 52/111 (46%), Positives = 77/111 (69%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F KI+ K +PAK V+ED   VAF D+NPQAPTH+L++PRK ++ +     ED+ L+G
Sbjct: 3   DCLFCKIVAKTLPAKIVHEDADTVAFEDLNPQAPTHVLIVPRKHVATMVDLAPEDDALVG 62

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
            L      +A   G+D  G+R+V+N  ++  QSV+H+H+HVLGGR++ WPP
Sbjct: 63  KLFRAGAAIAKARGIDGPGYRVVMNHNRDAGQSVFHIHLHVLGGRRMGWPP 113


>UniRef50_UPI0000DBEF88 Cluster: UPI0000DBEF88 related cluster; n=1;
           Rattus norvegicus|Rep: UPI0000DBEF88 UniRef100 entry -
           Rattus norvegicus
          Length = 133

 Score =  126 bits (304), Expect = 1e-28
 Identities = 67/132 (50%), Positives = 87/132 (65%), Gaps = 10/132 (7%)
 Frame = +2

Query: 8   EVELAKSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRK----- 172
           ++  A    PGGD IF KI+ KEIPAK V ED QC+AF  ++PQ PTH LVIP+K     
Sbjct: 4   QIAKAHVIKPGGDRIFSKIICKEIPAKIVLEDYQCLAFQGISPQVPTHFLVIPKKHINIF 63

Query: 173 -----PISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLH 337
                 ISQ+S+A D++E LLGHL+IV +K A   GL      +V+N+  +G QSVYH+H
Sbjct: 64  NEKKENISQISEADDDNESLLGHLMIVGKKCAVYLGLK---HWMVVNECVDG-QSVYHIH 119

Query: 338 VHVLGGRQLEWP 373
           +HVLGG Q+ WP
Sbjct: 120 LHVLGGWQVNWP 131


>UniRef50_Q5CSR7 Cluster: Histidine triad (HIT) family zinc binding
           protein; n=3; Alveolata|Rep: Histidine triad (HIT)
           family zinc binding protein - Cryptosporidium parvum
           Iowa II
          Length = 130

 Score =  126 bits (303), Expect = 2e-28
 Identities = 55/112 (49%), Positives = 81/112 (72%), Gaps = 2/112 (1%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRK--PISQLSKAGDEDEQLL 220
           TIF +I+  EIP + +YEDD C++FHD+NP AP H L++P+K   +++LSKA +  +++L
Sbjct: 20  TIFDRIVSGEIPCRKIYEDDLCISFHDINPVAPVHALLVPKKRSGLTRLSKATETHKEIL 79

Query: 221 GHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           GHL+     VA  + LD   FR+VINDG++  Q+V+HLH+H+LGGR   WPP
Sbjct: 80  GHLMTKVPVVA--KLLDLDDFRIVINDGESSCQTVFHLHIHILGGRNFTWPP 129


>UniRef50_Q7K6B1 Cluster: Protein kinase c inhibitor-like protein,
           putative; n=3; Plasmodium|Rep: Protein kinase c
           inhibitor-like protein, putative - Plasmodium falciparum
           (isolate 3D7)
          Length = 130

 Score =  125 bits (301), Expect = 3e-28
 Identities = 55/114 (48%), Positives = 82/114 (71%), Gaps = 2/114 (1%)
 Frame = +2

Query: 41  GDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIP--RKPISQLSKAGDEDEQ 214
           GD+IFGKI R E+P   VYEDD+ +AF+D+ PQAP HI+VIP  R  +++LSKA ++ ++
Sbjct: 18  GDSIFGKIARGEVPVDAVYEDDKVIAFNDIYPQAPVHIIVIPKRRDGLTRLSKAEEKHKE 77

Query: 215 LLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           +LGHL+    ++  +  L    FRLV+N+G    QS+Y+LH+H+L  RQ++WPP
Sbjct: 78  ILGHLMWAVAEIVRKNNL--GDFRLVVNNGPEACQSIYYLHLHILAKRQMKWPP 129


>UniRef50_Q892R5 Cluster: Hit family protein; n=16; Bacteria|Rep:
           Hit family protein - Clostridium tetani
          Length = 114

 Score =  124 bits (300), Expect = 4e-28
 Identities = 51/111 (45%), Positives = 81/111 (72%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI++ +IP++ VYED+  +AF D++P APTH+LVIP+K I  L++  D D +++ 
Sbjct: 3   DCIFCKIVKGDIPSEKVYEDELILAFKDISPSAPTHVLVIPKKHIKNLNELSDNDAKIIS 62

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           H+ I  +++A Q  +++ G+R+V N G+ G Q+V H+H H+LGGR L+WPP
Sbjct: 63  HIYIKIKELAQQLDINEKGYRVVTNCGEQGGQTVEHIHFHLLGGRNLQWPP 113


>UniRef50_Q1YR93 Cluster: Protein kinase C inhibitor; n=2;
           Gammaproteobacteria|Rep: Protein kinase C inhibitor -
           gamma proteobacterium HTCC2207
          Length = 120

 Score =  124 bits (299), Expect = 5e-28
 Identities = 53/101 (52%), Positives = 83/101 (82%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           T+F +I+ +EIPA+ +YEDD+C+  +D++PQAP H+LVIPR+PI++L+ A + D+ LLGH
Sbjct: 7   TLFTRIINREIPAEILYEDDKCIVINDISPQAPIHMLVIPRQPIAKLADAIEADKALLGH 66

Query: 227 LLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           L+ VA +VA Q G++++ FRLV+N+G+   Q+V+HLH+HVL
Sbjct: 67  LMWVAGEVARQAGVEEA-FRLVVNNGRAAGQTVFHLHLHVL 106


>UniRef50_Q1CY35 Cluster: HIT domain protein; n=3; Bacteria|Rep: HIT
           domain protein - Myxococcus xanthus (strain DK 1622)
          Length = 116

 Score =  123 bits (297), Expect = 1e-27
 Identities = 59/113 (52%), Positives = 76/113 (67%), Gaps = 2/113 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F KI    IPAK VY DD CVAF D+NPQAPTH+L IP K I  ++    ED +L+G
Sbjct: 3   DCLFCKIRDGLIPAKVVYRDDVCVAFEDINPQAPTHVLFIPHKHIPTVNDITTEDRELVG 62

Query: 224 HLLIVARKVATQEG-LDKS-GFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           HL I A KVA + G  D S G+R+V+N   +  Q+V+H+H+H+L GR L WPP
Sbjct: 63  HLFIAAAKVAQERGHADPSDGYRVVMNTHAHAGQTVFHIHLHLLAGRPLGWPP 115


>UniRef50_Q83DE2 Cluster: HIT family protein; n=24; Bacteria|Rep:
           HIT family protein - Coxiella burnetii
          Length = 113

 Score =  122 bits (294), Expect = 2e-27
 Identities = 53/109 (48%), Positives = 77/109 (70%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F KI + EI  + +YED Q VAF+D  PQAP HILVIP + I  ++     DE LLGH+
Sbjct: 5   VFCKIAKGEI-GELIYEDKQVVAFNDAAPQAPIHILVIPHRHIETINDVTPGDEDLLGHM 63

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           ++VA ++A  + +   G+RLV+N  +NG Q+V+H+H+H+LGGRQ+ WPP
Sbjct: 64  VVVATRLAHDKNMAADGYRLVMNCNRNGGQAVFHIHLHLLGGRQMHWPP 112


>UniRef50_Q8KGB0 Cluster: HIT family protein; n=10; Bacteria|Rep:
           HIT family protein - Chlorobium tepidum
          Length = 128

 Score =  119 bits (286), Expect = 2e-26
 Identities = 52/111 (46%), Positives = 74/111 (66%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI    IPA  VY++D   AFHD+NP AP H+L+IP + I  LS   D D ++  
Sbjct: 7   DCIFCKIATGHIPANLVYKNDHVAAFHDINPVAPIHVLIIPLEHIRSLSDLKDGDSEIAA 66

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
            +L+ AR VA + G+ +SG+RLV N+G++  QSV H+H H++GG+ + WPP
Sbjct: 67  QILLAARIVAEKTGVLESGYRLVFNNGEDALQSVGHIHAHLIGGKTMGWPP 117


>UniRef50_A0BUI5 Cluster: Chromosome undetermined scaffold_129,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_129,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 117

 Score =  118 bits (285), Expect = 3e-26
 Identities = 49/106 (46%), Positives = 75/106 (70%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           T+F KI++++IPAK +YED  C+AF D+NP+A  H+LVIP++ + +LS A ++   LLG+
Sbjct: 10  TVFEKIIKRQIPAKIIYEDKHCLAFEDINPKAKVHVLVIPKEHLDRLSNASEQHINLLGN 69

Query: 227 LLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           L+    +V  Q  L   G+R++INDG+ G Q+V+HLH H+L G  L
Sbjct: 70  LMYAVNRVGKQ--LQLEGYRVIINDGQKGGQTVFHLHAHILSGENL 113


>UniRef50_Q3J6P8 Cluster: Histidine triad (HIT) protein; n=5;
           Proteobacteria|Rep: Histidine triad (HIT) protein -
           Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 115

 Score =  116 bits (279), Expect = 1e-25
 Identities = 53/107 (49%), Positives = 75/107 (70%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI+  E+PAK VYEDDQ +AF D++P+A  H+L++PR  IS L +   + E L+ 
Sbjct: 7   DCIFCKIIEGELPAKVVYEDDQVIAFEDIHPKAKIHLLLVPRSHISSLEQLEVKHEALIS 66

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           HLL++   +A ++GL + GFR +IN G+ G Q V HLH+H+LGG QL
Sbjct: 67  HLLLLLPDLARRQGL-QDGFRTIINTGRGGGQEVDHLHIHLLGGSQL 112


>UniRef50_Q4JN62 Cluster: Predicted protein kinase C inhibitor
           chPKCI; n=1; uncultured bacterium BAC13K9BAC|Rep:
           Predicted protein kinase C inhibitor chPKCI - uncultured
           bacterium BAC13K9BAC
          Length = 114

 Score =  114 bits (275), Expect = 4e-25
 Identities = 49/111 (44%), Positives = 74/111 (66%), Gaps = 1/111 (0%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGD-EDEQLLG 223
           T+F +I+ KEIP+  +YED  C+   D++PQAP H L IP+K I  +S   D ED+ +LG
Sbjct: 5   TVFQQIINKEIPSNIIYEDQLCIIIEDISPQAPIHYLAIPKKMIKGISDLNDNEDKDILG 64

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           H++I  +   T+  ++ + +RLVIN+G    Q+V+HLH+H+L  R L WPP
Sbjct: 65  HMMISIKNQMTK--MNINDYRLVINNGSEAGQTVFHLHIHILANRTLGWPP 113


>UniRef50_Q4N9V7 Cluster: Protein kinase C interacting protein 1,
           putative; n=2; Theileria|Rep: Protein kinase C
           interacting protein 1, putative - Theileria parva
          Length = 180

 Score =  112 bits (270), Expect = 2e-24
 Identities = 51/122 (41%), Positives = 81/122 (66%), Gaps = 2/122 (1%)
 Frame = +2

Query: 17  LAKSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRK--PISQLS 190
           +  S  P   T+F KI++ E+P K VYEDD  +AF+D+ P +P+HIL+IP++   ++ LS
Sbjct: 60  MPNSENPEELTVFHKIVKGELPCKKVYEDDLVLAFYDIQPASPSHILIIPKEMDGLASLS 119

Query: 191 KAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEW 370
            A +  E++LGH+L+ A  +A +  L    FR+VIN G    Q+V++LH+H++ GR+  W
Sbjct: 120 DATERHEKVLGHMLVKAAHIAKENNL--GDFRVVINSGPGALQTVFYLHMHLMSGRRFNW 177

Query: 371 PP 376
           PP
Sbjct: 178 PP 179


>UniRef50_Q182D4 Cluster: Histidine triad nucleotide-binding
           protein; n=7; Bacteria|Rep: Histidine triad
           nucleotide-binding protein - Clostridium difficile
           (strain 630)
          Length = 116

 Score =  112 bits (269), Expect = 2e-24
 Identities = 49/107 (45%), Positives = 73/107 (68%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI   EIP+  VYEDD+ +AF+D+NP AP HILV+P+K    L    D++  ++ 
Sbjct: 2   DCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKKHYDSLIDIPDKEMDIVS 61

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           H+ +V  K+A ++G D++GFR++ N G +G Q V HLH H+L G++L
Sbjct: 62  HIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHILAGKKL 108


>UniRef50_A3EUM2 Cluster: Histidine triad protein; n=1;
           Leptospirillum sp. Group II UBA|Rep: Histidine triad
           protein - Leptospirillum sp. Group II UBA
          Length = 118

 Score =  109 bits (262), Expect = 2e-23
 Identities = 55/113 (48%), Positives = 72/113 (63%), Gaps = 2/113 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKA--GDEDEQL 217
           + IF +IL  EIP+K + E+   VA  DVNPQAP H LV+ R+ +  ++     D  E +
Sbjct: 5   ECIFCRILNGEIPSKKILEEADGVAILDVNPQAPFHALVLSRRHVGDMATLLKVDGGELV 64

Query: 218 LGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
            G L+ +A  VA   GL   G+R+VIN G NG Q+V HLHVHVLGGRQ+ WPP
Sbjct: 65  AGKLMRMAVNVARDAGLSPDGYRVVINTGNNGGQTVAHLHVHVLGGRQMVWPP 117


>UniRef50_A7AQA5 Cluster: HIT domain containing protein; n=1;
           Babesia bovis|Rep: HIT domain containing protein -
           Babesia bovis
          Length = 180

 Score =  109 bits (261), Expect = 2e-23
 Identities = 48/112 (42%), Positives = 73/112 (65%), Gaps = 2/112 (1%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKP--ISQLSKAGDEDEQLL 220
           T+F +I+   IP   VYED+  +AFHD+ P AP H LVIP++   +++LS A D   ++L
Sbjct: 70  TVFDRIVDGSIPCVKVYEDEHILAFHDIKPVAPVHFLVIPKRHAGLTRLSNATDAHAKIL 129

Query: 221 GHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           G++++   ++     L+   +RLVINDG    Q ++HLH+HV+ GRQL WPP
Sbjct: 130 GYMMVKVAEIT--RSLNIGDYRLVINDGAGAGQQIFHLHMHVIAGRQLSWPP 179


>UniRef50_Q7W2X6 Cluster: MttA/Hcf106 family protein; n=30;
           Burkholderiales|Rep: MttA/Hcf106 family protein -
           Bordetella parapertussis
          Length = 122

 Score =  107 bits (258), Expect = 5e-23
 Identities = 51/105 (48%), Positives = 67/105 (63%), Gaps = 3/105 (2%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI R EIPAK V+EDD+ VAFHD+NP AP H+L+IPR+ +  L    + D   LG +
Sbjct: 6   IFCKIARGEIPAKKVFEDDEFVAFHDINPAAPVHLLLIPRRHVVSLQDIAEGDADWLGRM 65

Query: 230 LIVARKVATQEGLD---KSGFRLVINDGKNGAQSVYHLHVHVLGG 355
            ++A ++A   G +     GFRL+ N G  G Q V HLH H+LGG
Sbjct: 66  TVLASRLAAGNGCNPGPDGGFRLMANSGAEGGQEVPHLHFHILGG 110


>UniRef50_A6T373 Cluster: HIT family protein; n=20;
           Betaproteobacteria|Rep: HIT family protein -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 128

 Score =  106 bits (255), Expect = 1e-22
 Identities = 50/111 (45%), Positives = 72/111 (64%), Gaps = 9/111 (8%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI  K+IPA+ +YEDD  +AF+D+NP AP H L+IP+K ++ L+    ED  LLG +
Sbjct: 9   IFCKIAAKQIPAQIIYEDDDLLAFNDINPAAPVHFLIIPKKHVATLADCTTEDAALLGKI 68

Query: 230 LIVARKVATQE---------GLDKSGFRLVINDGKNGAQSVYHLHVHVLGG 355
            ++A K+A ++         G+   GF+ + N G +G Q VYHLH+HVLGG
Sbjct: 69  SLLAPKLAQEQGVGYRADGNGVGSGGFKTLFNIGPDGGQEVYHLHMHVLGG 119


>UniRef50_O07817 Cluster: Protein hitA; n=7; Betaproteobacteria|Rep:
           Protein hitA - Neisseria gonorrhoeae
          Length = 107

 Score =  104 bits (249), Expect = 6e-22
 Identities = 47/101 (46%), Positives = 66/101 (65%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI  KEIPA+ VYED + V F D+NP AP H+L+IP+     L+ A  E + LLG +
Sbjct: 5   IFCKIAAKEIPAQTVYEDGEMVCFKDINPAAPLHLLLIPKVHFDSLAHAAPEHQPLLGKM 64

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLG 352
           ++   ++A   GL   GF+ +IN GK G Q V+HLH+H++G
Sbjct: 65  MLKVPEIAKASGL-TDGFKTLINTGKGGGQEVFHLHIHIMG 104


>UniRef50_A7A616 Cluster: Putative uncharacterized protein; n=2;
           Bifidobacterium adolescentis|Rep: Putative
           uncharacterized protein - Bifidobacterium adolescentis
           L2-32
          Length = 124

 Score =  102 bits (245), Expect = 2e-21
 Identities = 48/115 (41%), Positives = 72/115 (62%)
 Frame = +2

Query: 23  KSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGD 202
           +S     D +F KI+  EIP++ VYEDD   AF D+NP+A  H+L++PRK  + +++   
Sbjct: 11  RSVMSDKDCLFCKIIAGEIPSEKVYEDDATYAFKDINPKAKVHVLIVPRKHYANVAELAK 70

Query: 203 EDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLE 367
           ED   L H+  VA+K+A QE      FRL+ N G +  Q+V+H+H HVL G +L+
Sbjct: 71  EDPAQLAHMAEVAQKIADQE--FHGAFRLIFNTGIDAGQTVFHVHAHVLTGEKLD 123


>UniRef50_Q93IL6 Cluster: Histidine nucleotide-binding protein; n=3;
           Thermus thermophilus|Rep: Histidine nucleotide-binding
           protein - Thermus thermophilus
          Length = 107

 Score =  102 bits (244), Expect = 3e-21
 Identities = 48/106 (45%), Positives = 73/106 (68%), Gaps = 2/106 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGD--EDEQL 217
           + +F +I+  E+P+K VYED+  VAFHD+ P+AP H+LV+P++ + +LS   D  E E+ 
Sbjct: 2   ECVFCRIIAGELPSKKVYEDEGFVAFHDIRPKAPVHVLVVPKEHVEKLSDYPDTEEGERK 61

Query: 218 LGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGG 355
           LG L   A +VA   GL+  G+R+ +N G+ G Q V+H+HVHV+GG
Sbjct: 62  LGALFRTANRVARVLGLE--GYRVQVNVGEKGGQEVFHVHVHVMGG 105


>UniRef50_Q2LVF0 Cluster: Hit family hydrolase; n=1; Syntrophus
           aciditrophicus SB|Rep: Hit family hydrolase - Syntrophus
           aciditrophicus (strain SB)
          Length = 116

 Score =  100 bits (239), Expect = 1e-20
 Identities = 42/105 (40%), Positives = 68/105 (64%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F  I++ EIP   +YEDD  +AF D++P AP H++V+P++ IS      D+    L  +
Sbjct: 6   LFCSIVKGEIPCARIYEDDHVLAFEDIHPMAPVHVVVVPKRHISTFMDVSDDTMAYLMSM 65

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           +  A+K+A  + +D+ GFR VIN  + G Q ++HLH+H+LGG +L
Sbjct: 66  MTAAQKIAKLKAIDEKGFRTVINCKEEGGQVIFHLHMHLLGGCKL 110


>UniRef50_A1SHY4 Cluster: Histidine triad (HIT) protein precursor;
           n=4; Actinobacteridae|Rep: Histidine triad (HIT) protein
           precursor - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 112

 Score = 99.5 bits (237), Expect = 2e-20
 Identities = 45/111 (40%), Positives = 67/111 (60%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F KI+  +IP + V+  ++ VAF D++P+APTH+LV+PR   +  ++    D Q   
Sbjct: 3   DCLFCKIVAGDIPGEVVHTTERTVAFRDIDPKAPTHVLVVPRDHYTNAAELAAADPQATA 62

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
            L+  A  VA  EG   + +R+V N G    QSV+H H+H+L GR L WPP
Sbjct: 63  ELVTTAAAVAAAEGY--ADYRIVFNTGAEAGQSVFHTHLHLLAGRPLTWPP 111


>UniRef50_A0LCF6 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein -
           Magnetococcus sp. (strain MC-1)
          Length = 117

 Score = 99.5 bits (237), Expect = 2e-20
 Identities = 45/107 (42%), Positives = 68/107 (63%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F KI+   IP   VYED+  +AF D++PQAP H+LVIP++ I+ L     +   ++G
Sbjct: 4   DCLFCKIVAGTIPCNKVYEDELVLAFRDIHPQAPEHVLVIPKQHIATLDDVQVQARAVMG 63

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           HL+     VA   G+ + G+R +IN   +G Q VYH+HVH+LGG+ +
Sbjct: 64  HLMERTAHVARLIGVAEKGYRTLINTRGDGGQEVYHIHVHILGGKAI 110


>UniRef50_A4F9S9 Cluster: Protein kinase C inhibitor; n=3;
           Actinomycetales|Rep: Protein kinase C inhibitor -
           Saccharopolyspora erythraea (strain NRRL 23338)
          Length = 123

 Score = 99.1 bits (236), Expect = 2e-20
 Identities = 42/107 (39%), Positives = 70/107 (65%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F +I+  EI A  V E D+ +A  D+NPQAPTH+LV+P+      ++   +D  LL 
Sbjct: 7   DDLFLRIIAGEISADVVRETDRVIAIRDINPQAPTHVLVVPKTRYRNAAELAAKDPDLLA 66

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
            ++ VA +VA  EG+ +SG+RL+ N   +  Q+++H+H+H+LGG ++
Sbjct: 67  EVVRVAGEVAESEGIAESGYRLLFNTNSDAGQTIFHVHLHLLGGERM 113


>UniRef50_A6WDH4 Cluster: Histidine triad (HIT) protein; n=2;
           Actinomycetales|Rep: Histidine triad (HIT) protein -
           Kineococcus radiotolerans SRS30216
          Length = 121

 Score = 98.7 bits (235), Expect = 3e-20
 Identities = 49/111 (44%), Positives = 67/111 (60%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F +I+  E+PA  V+ DD  VAF DVNPQAP H+LVIPR+    +++        L 
Sbjct: 12  DDLFLRIVAGEVPATIVHSDDLVVAFEDVNPQAPVHVLVIPRERHENVAQLAAAAPATLA 71

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
            L+ VA+++A +       +RLV N G    QSV+H+H HVLGGR   WPP
Sbjct: 72  RLVEVAQRIADER--CGGEYRLVFNTGTAVGQSVFHVHGHVLGGRGFTWPP 120


>UniRef50_Q9SA09 Cluster: F28K20.9 protein; n=7; Magnoliophyta|Rep:
           F28K20.9 protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 214

 Score = 98.7 bits (235), Expect = 3e-20
 Identities = 61/148 (41%), Positives = 83/148 (56%), Gaps = 29/148 (19%)
 Frame = +2

Query: 20  AKSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIP--RKPISQLSK 193
           A  A  G  TIF KI+ KEIP+  VYED+  +AF D+NPQAP H+LVIP  R  ++ L K
Sbjct: 67  ASVADTGAPTIFDKIIAKEIPSDIVYEDENVLAFRDINPQAPVHVLVIPKLRDGLTSLGK 126

Query: 194 AGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQS------------VYHL- 334
           A     ++LG LL  ++ VA +EG+   GFR+VIN+G    +S            + H+ 
Sbjct: 127 AEPRHVEVLGQLLHASKIVAEKEGI-LDGFRVVINNGVEACKSFLFFSIQLSIIVLIHMT 185

Query: 335 --------------HVHVLGGRQLEWPP 376
                         H+HVLGGRQ++WPP
Sbjct: 186 ELTSSHSGQSVYHLHLHVLGGRQMKWPP 213


>UniRef50_Q0BPX6 Cluster: Adenosine 5'-monophosphoramidase; n=7;
           Alphaproteobacteria|Rep: Adenosine
           5'-monophosphoramidase - Granulobacter bethesdensis
           (strain ATCC BAA-1260 / CGDNIH1)
          Length = 136

 Score = 98.3 bits (234), Expect = 4e-20
 Identities = 48/108 (44%), Positives = 65/108 (60%), Gaps = 1/108 (0%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKP-ISQLSKAGDEDEQLL 220
           D IF  ILR EIP + V E+D  +AF D+NPQAPTH+L+IP+KP IS          + +
Sbjct: 20  DNIFALILRGEIPCRKVMENDHALAFLDINPQAPTHVLIIPKKPYISFADFTERASAEEV 79

Query: 221 GHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           G   +   K+A   GL+  G+RL+ N G++  Q V H HVH+  GR L
Sbjct: 80  GTFFLTVGKLARDMGLEVPGYRLLANSGQDAGQEVPHFHVHLFAGRPL 127


>UniRef50_A3DF72 Cluster: Histidine triad (HIT) protein; n=2;
           Clostridium thermocellum|Rep: Histidine triad (HIT)
           protein - Clostridium thermocellum (strain ATCC 27405 /
           DSM 1237)
          Length = 114

 Score = 98.3 bits (234), Expect = 4e-20
 Identities = 40/102 (39%), Positives = 68/102 (66%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F KI+++E+P+   YED++ +A  D+NP AP H+L+IP++ I+ + +  + + Q+L  +
Sbjct: 5   VFCKIIKRELPSTIYYEDERVIAIKDINPAAPVHVLIIPKEHIANVKEINESNAQILIDI 64

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGG 355
              A KVA   G+ + G+RL+ N G    Q+V+HLH H+LGG
Sbjct: 65  HKAANKVAEDLGIAEKGYRLITNCGVAAGQTVFHLHYHLLGG 106


>UniRef50_Q7M8Z0 Cluster: HIT-FAMILY PROTEIN; n=12;
           Epsilonproteobacteria|Rep: HIT-FAMILY PROTEIN -
           Wolinella succinogenes
          Length = 120

 Score = 97.5 bits (232), Expect = 7e-20
 Identities = 44/108 (40%), Positives = 68/108 (62%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           T+F +I+  EIP   V+E+   +AFHD+NP+AP H+L IP+K      +    D   +G 
Sbjct: 2   TLFERIVAGEIPCNKVHENSDFLAFHDINPKAPIHVLAIPKKCARSFQEV---DPSWMGG 58

Query: 227 LLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEW 370
           +    ++VA + GLD++G+R++ N G +G Q V HLH H+LGG +L W
Sbjct: 59  MTSFIQEVARKLGLDEAGYRVITNIGYDGGQEVPHLHFHILGGTRLAW 106


>UniRef50_Q8K9I9 Cluster: Uncharacterized HIT-like protein BUsg_345;
           n=4; Enterobacteriaceae|Rep: Uncharacterized HIT-like
           protein BUsg_345 - Buchnera aphidicola subsp. Schizaphis
           graminum
          Length = 115

 Score = 97.1 bits (231), Expect = 1e-19
 Identities = 40/108 (37%), Positives = 69/108 (63%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI+++E     +Y+D    AF D+ P+AP HI+VIP   I  L+    +++ +  
Sbjct: 5   DLIFQKIIKRETSTHIIYQDKIVTAFEDIAPKAPIHIIVIPNIFIKTLNDINQKNKNIFA 64

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLE 367
           H+L +A K+A  + + + G+++V+N  KNG Q + +LH+H+LGG +L+
Sbjct: 65  HMLYIAVKIAKNKKISEDGYKIVMNCNKNGGQEINYLHMHLLGGEKLK 112


>UniRef50_A7H3E9 Cluster: HIT family protein; n=11;
           Campylobacter|Rep: HIT family protein - Campylobacter
           jejuni subsp. doylei 269.97
          Length = 121

 Score = 96.3 bits (229), Expect = 2e-19
 Identities = 46/106 (43%), Positives = 66/106 (62%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           TIF  I+  ++P   V E D  +AFHD+ P+AP HIL+IP+K      +    D +L+  
Sbjct: 5   TIFELIVEGKLPCNKVLESDDFLAFHDIAPKAPIHILIIPKKHFKDFQEF---DPELMAK 61

Query: 227 LLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           +    +++A   G+DKSG+RLV N GKN  Q V+HLH H+LGG +L
Sbjct: 62  MTSFIQELAVLLGVDKSGYRLVTNCGKNSGQEVFHLHFHMLGGFEL 107


>UniRef50_Q9ZDL1 Cluster: Uncharacterized HIT-like protein RP317;
           n=13; Rickettsiales|Rep: Uncharacterized HIT-like
           protein RP317 - Rickettsia prowazekii
          Length = 120

 Score = 95.1 bits (226), Expect = 4e-19
 Identities = 42/111 (37%), Positives = 68/111 (61%), Gaps = 4/111 (3%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQ----LSKAGDEDE 211
           + +F KI+ K +PA+ +YED Q +AF D+ P AP HI+VIP+         +SKA  ++ 
Sbjct: 5   ENVFAKIITKNLPAEIIYEDKQILAFKDIAPIAPVHIIVIPKNEYIDYTDFISKASIDE- 63

Query: 212 QLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
             + H       +A + GLDK G+RL+ N G+   Q+++H H H++GG++L
Sbjct: 64  --IKHFFSKIADIANEAGLDKVGYRLITNKGEKSGQTIFHFHFHIIGGKKL 112


>UniRef50_Q23921 Cluster: Protein pkiA; n=4; Dictyostelium
           discoideum|Rep: Protein pkiA - Dictyostelium discoideum
           (Slime mold)
          Length = 172

 Score = 94.3 bits (224), Expect = 7e-19
 Identities = 45/105 (42%), Positives = 67/105 (63%), Gaps = 4/105 (3%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDED----E 211
           DTIF KI+   IP+K  Y+D+ C+A  D+NPQAP H+LVIP+  +  LS   + D    +
Sbjct: 67  DTIFAKIISGAIPSKKFYDDEYCIAIEDINPQAPVHLLVIPKLAVGGLSDVANVDLEKYK 126

Query: 212 QLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHV 346
           + +GH++     +A+ +G D   +RLVIN+G  G QSV  LH+H+
Sbjct: 127 ESMGHIMSKIHHIASLKGAD--SYRLVINEGVLGQQSVRWLHIHI 169


>UniRef50_Q5GT45 Cluster: HIT family hydrolase; n=4;
           Rickettsiales|Rep: HIT family hydrolase - Wolbachia sp.
           subsp. Brugia malayi (strain TRS)
          Length = 122

 Score = 93.1 bits (221), Expect = 2e-18
 Identities = 50/111 (45%), Positives = 73/111 (65%), Gaps = 4/111 (3%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKP-ISQ---LSKAGDEDE 211
           + IF +ILR E+P K VYED+  +AF+D  P AP HILV+P+   IS    + KA    E
Sbjct: 9   NNIFAQILRGELPCKKVYEDEDVLAFYDKYPDAPVHILVVPKSQYISYDDFIFKA--SAE 66

Query: 212 QLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           +++G    V R++  +  L+K+G+RLV N G+NG Q V H H+H+LGG++L
Sbjct: 67  EIVGFFKTV-REITYKYNLEKTGYRLVTNCGENGEQVVPHFHMHILGGKRL 116


>UniRef50_A5CF29 Cluster: Protein kinase C inhibitor 1; n=1;
           Orientia tsutsugamushi Boryong|Rep: Protein kinase C
           inhibitor 1 - Orientia tsutsugamushi (strain Boryong)
           (Rickettsia tsutsugamushi)
          Length = 123

 Score = 91.9 bits (218), Expect = 4e-18
 Identities = 45/112 (40%), Positives = 67/112 (59%), Gaps = 4/112 (3%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQ----LSKAGDEDE 211
           + +F KILR E+ A  VY+D++ +AFHD+NP + THILVIP          LSKA  +D 
Sbjct: 13  NNVFAKILRNELSANIVYKDNKILAFHDINPISSTHILVIPNGEYIDYCDFLSKASPDD- 71

Query: 212 QLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLE 367
             + H       +  Q  LD+SGF+LV ++GK G Q + H H H++  +++E
Sbjct: 72  --ICHYFSTINSMVKQFKLDQSGFKLVTHNGKGGGQEIPHFHTHIISNQKIE 121


>UniRef50_P26724 Cluster: Uncharacterized 13.2 kDa HIT-like protein
           in hisE 3'region; n=33; Alphaproteobacteria|Rep:
           Uncharacterized 13.2 kDa HIT-like protein in hisE
           3'region - Azospirillum brasilense
          Length = 122

 Score = 91.5 bits (217), Expect = 5e-18
 Identities = 48/117 (41%), Positives = 69/117 (58%), Gaps = 1/117 (0%)
 Frame = +2

Query: 17  LAKSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSK- 193
           +AK+  P  + +F +ILR EIP K V E +  +AFHD+NPQAPTHILVIP+     +   
Sbjct: 1   MAKTYDP--NNVFARILRGEIPCKKVLETEHALAFHDINPQAPTHILVIPKGAYVDMDDF 58

Query: 194 AGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           +    E  +  L     +VA   G  + G+R++ N G++  Q V HLH+HV  GR+L
Sbjct: 59  SARATEAEIAGLFRAVGEVARGAGAAEPGYRILSNCGEDANQEVPHLHIHVFAGRRL 115


>UniRef50_Q0JIB7 Cluster: Os01g0813000 protein; n=3; Oryza
           sativa|Rep: Os01g0813000 protein - Oryza sativa subsp.
           japonica (Rice)
          Length = 235

 Score = 79.4 bits (187), Expect(2) = 6e-18
 Identities = 37/73 (50%), Positives = 53/73 (72%), Gaps = 2/73 (2%)
 Frame = +2

Query: 107 QCVAFHDVNPQAPTHILVIP--RKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSG 280
           Q +AF D++PQAP HI++IP  +  +S+LSKA +   +++GHLL  A+ +A QE LD  G
Sbjct: 145 QTLAFRDISPQAPVHIIIIPKVKDGLSRLSKAEERHVEVMGHLLYAAKTIAKQENLD-DG 203

Query: 281 FRLVINDGKNGAQ 319
           FR+VINDG NG +
Sbjct: 204 FRIVINDGPNGCE 216



 Score = 32.3 bits (70), Expect(2) = 6e-18
 Identities = 13/19 (68%), Positives = 17/19 (89%)
 Frame = +2

Query: 53  FGKILRKEIPAKFVYEDDQ 109
           F KILRKEIP++ VYED++
Sbjct: 93  FDKILRKEIPSQVVYEDEK 111


>UniRef50_Q8AYA7 Cluster: ASW-related protein; n=1; Taeniopygia
           guttata|Rep: ASW-related protein - Poephila guttata
           (Zebra finch) (Taeniopygia guttata)
          Length = 107

 Score = 91.1 bits (216), Expect = 6e-18
 Identities = 43/91 (47%), Positives = 59/91 (64%)
 Frame = +2

Query: 104 DQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGF 283
           + C  FHD+ P   T  LV+P++PI +LS+AG   E LLGH++IV         L  +GF
Sbjct: 17  ESCRTFHDLLPLDGTLFLVMPKEPIIELSEAGASGESLLGHVMIVGEMCVAHLVLT-NGF 75

Query: 284 RLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
           R+V+++   G QSVYH+H+ VLGG QL WPP
Sbjct: 76  RMVLDERPEGGQSVYHMHLPVLGGLQLGWPP 106


>UniRef50_A7HMY4 Cluster: Histidine triad (HIT) protein; n=2;
           Thermotogaceae|Rep: Histidine triad (HIT) protein -
           Fervidobacterium nodosum Rt17-B1
          Length = 111

 Score = 90.6 bits (215), Expect = 8e-18
 Identities = 40/107 (37%), Positives = 68/107 (63%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F KI+  +IP++ VYED+  +   D+ P AP H+L I +K I+ ++   +ED + + 
Sbjct: 3   DCVFCKIIDGQIPSEKVYEDNDFIVIKDIRPVAPVHLLAIYKKHIATINDLSEEDSKNMW 62

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
            L  V +KV   + L+   +R+V N+GK+  Q V+H+H H++GGR+L
Sbjct: 63  KLFEVIKKVTKDQNLE--SYRIVQNNGKDAGQEVHHIHFHIIGGRKL 107


>UniRef50_A5IXY8 Cluster: HIT-like protein; n=1; Mycoplasma
           agalactiae|Rep: HIT-like protein - Mycoplasma agalactiae
          Length = 111

 Score = 90.6 bits (215), Expect = 8e-18
 Identities = 46/104 (44%), Positives = 65/104 (62%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F KI+  E   K  Y+DD CVAF+D  P  P H LV+PR     +++A   D+    
Sbjct: 2   DDLFLKIISGEEEGKIFYKDDVCVAFYDKFPIQPGHFLVVPRVKSKNITEA---DDFTAA 58

Query: 224 HLLIVARKVATQEGLDK--SGFRLVINDGKNGAQSVYHLHVHVL 349
           HL+  ARK+  QE LDK  +GF+++IN GK+  QS++H HVHV+
Sbjct: 59  HLINTARKLGKQEVLDKGIAGFKILINTGKSADQSIFHTHVHVI 102


>UniRef50_Q9RTX9 Cluster: Hit family protein; n=2; Deinococcus|Rep:
           Hit family protein - Deinococcus radiodurans
          Length = 118

 Score = 89.8 bits (213), Expect = 1e-17
 Identities = 41/103 (39%), Positives = 68/103 (66%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           T+F +I+ +EIP++ VYEDD  +A  D+ P+AP H+LVIP++  +++ +  D  E  +G 
Sbjct: 12  TLFERIIAREIPSQVVYEDDDYIAIKDIAPKAPIHLLVIPKRVTTRVDEITDPLE--MGR 69

Query: 227 LLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGG 355
           L + A ++A ++  D   +RLV+N G  G Q V+H H+H+L G
Sbjct: 70  LWLKATEIAREQAPD---YRLVVNCGAGGGQMVFHTHIHILAG 109


>UniRef50_Q9PK09 Cluster: Uncharacterized HIT-like protein TC_0664;
           n=9; Chlamydiales|Rep: Uncharacterized HIT-like protein
           TC_0664 - Chlamydia muridarum
          Length = 126

 Score = 89.8 bits (213), Expect = 1e-17
 Identities = 43/111 (38%), Positives = 67/111 (60%)
 Frame = +2

Query: 23  KSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGD 202
           K+A     TIF +I+   +    V+ED+  +   D  PQAP H+L+IP+K I +L     
Sbjct: 10  KTAGGSMTTIFERIIEGAVECDKVFEDENFIVIKDKFPQAPVHLLIIPKKHIEKLQDMQS 69

Query: 203 EDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGG 355
           +D  LL     + + +A   G++ +G+R+VIN+G  G QSV+HLH+H+LGG
Sbjct: 70  DDFSLLSEAGKIIQLMARDFGIE-NGYRVVINNGLEGGQSVFHLHIHLLGG 119


>UniRef50_Q98RK0 Cluster: HIT-LIKE PROTEIN; n=2; Mycoplasma|Rep:
           HIT-LIKE PROTEIN - Mycoplasma pulmonis
          Length = 116

 Score = 87.8 bits (208), Expect = 6e-17
 Identities = 44/109 (40%), Positives = 68/109 (62%), Gaps = 2/109 (1%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           +IF KI+ ++ PA+ +YEDDQ +A  D  P  P H LVIP+K  + L    D +EQ + H
Sbjct: 7   SIFKKIIDRKEPAQIIYEDDQAIAIMDKFPYNPGHFLVIPKKHSTNLK---DIEEQSINH 63

Query: 227 LLIVARKVATQ--EGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLE 367
           L+ +A K+A +  E  +   F+L+IN+G+   Q VYH H+H++  R+ E
Sbjct: 64  LMKIAIKLAKEKIENKEFEDFKLIINNGEKAGQVVYHTHIHIIPFRKKE 112


>UniRef50_A5BDT4 Cluster: Putative uncharacterized protein; n=2;
           cellular organisms|Rep: Putative uncharacterized protein
           - Vitis vinifera (Grape)
          Length = 420

 Score = 85.8 bits (203), Expect = 2e-16
 Identities = 39/75 (52%), Positives = 54/75 (72%)
 Frame = +2

Query: 152 ILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYH 331
           +L++ R  +  + +A +    +LGHLL  A+ VA QEGL+  GFR+VINDG +  QSVYH
Sbjct: 346 VLMVFRGFMXFIFQAEERHSVILGHLLYTAKLVAKQEGLE-DGFRIVINDGPSACQSVYH 404

Query: 332 LHVHVLGGRQLEWPP 376
           +HVH+LGGRQ+ WPP
Sbjct: 405 IHVHLLGGRQMNWPP 419



 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 31/51 (60%), Positives = 38/51 (74%), Gaps = 1/51 (1%)
 Frame = +2

Query: 20  AKSAAPGGD-TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPR 169
           A +A P    TIF KI+ KEIPA  VYEDD+ +AF D+ PQAPTHIL+IP+
Sbjct: 39  AVAATPSDSPTIFDKIINKEIPATIVYEDDKVLAFRDIAPQAPTHILLIPK 89


>UniRef50_Q6AEC2 Cluster: Putative uncharacterized protein; n=3;
           Actinobacteria (class)|Rep: Putative uncharacterized
           protein - Leifsonia xyli subsp. xyli
          Length = 132

 Score = 83.4 bits (197), Expect = 1e-15
 Identities = 39/102 (38%), Positives = 61/102 (59%), Gaps = 1/102 (0%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPR-KPISQLSKAGDEDEQLLG 223
           ++F +I+  EIPA  VY+ ++ +AF D+ PQAP H+LV+P+      + +    D +LL 
Sbjct: 18  SVFTRIIAGEIPADVVYDGERLIAFKDIAPQAPVHLLVVPKTDQYRDVVELAAGDPELLA 77

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            L+  AR +A +       FRL+ N G N  Q+V+H+H HVL
Sbjct: 78  ELVATARSLAAEHA--DGDFRLIFNTGANAGQTVFHVHAHVL 117


>UniRef50_UPI000050FA96 Cluster: COG0537: Diadenosine tetraphosphate
           (Ap4A) hydrolase and other HIT family hydrolases; n=1;
           Brevibacterium linens BL2|Rep: COG0537: Diadenosine
           tetraphosphate (Ap4A) hydrolase and other HIT family
           hydrolases - Brevibacterium linens BL2
          Length = 134

 Score = 81.0 bits (191), Expect = 7e-15
 Identities = 47/102 (46%), Positives = 59/102 (57%), Gaps = 2/102 (1%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           TIF KI+  EIP  FVY+DD CVAF DV+P    H +V+PR+ IS      D D+ LL H
Sbjct: 3   TIFTKIINGEIPGTFVYQDDLCVAFLDVSPMTEGHTMVVPREEISHWI---DADQDLLDH 59

Query: 227 LLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHV 346
           L+ V+RKV  A QE  D     ++I         V HLH+HV
Sbjct: 60  LMAVSRKVGRAQQEAFDCERIGVMIQ-----GYEVPHLHIHV 96


>UniRef50_Q83MZ3 Cluster: HIT-like protein; n=2; Tropheryma
           whipplei|Rep: HIT-like protein - Tropheryma whipplei
           (strain Twist) (Whipple's bacillus)
          Length = 107

 Score = 79.4 bits (187), Expect = 2e-14
 Identities = 36/106 (33%), Positives = 63/106 (59%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           +IF +I+ +E+PA+ ++EDD+ +   D+ P+A  H LVI + P   +++A  +D   +  
Sbjct: 3   SIFTRIINREVPAEILFEDDEFICIEDIAPKAKIHYLVIAKHPWKDVTEAVRDDPLFVNK 62

Query: 227 LLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           +L +A ++    G   S FRL+ N G    Q+V+H+H H+L G  L
Sbjct: 63  ILAIAVRLTKDFG---SQFRLIFNTGALVGQTVFHVHAHILSGEAL 105


>UniRef50_P32083 Cluster: Uncharacterized 13.1 kDa HIT-like protein
           in P37 5'region; n=5; Mycoplasma|Rep: Uncharacterized
           13.1 kDa HIT-like protein in P37 5'region - Mycoplasma
           hyorhinis
          Length = 111

 Score = 79.4 bits (187), Expect = 2e-14
 Identities = 40/104 (38%), Positives = 63/104 (60%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           + +F KI+++E PA  +YEDD+ +AF D       H LV+P+     L    DED   L 
Sbjct: 6   EELFLKIIKREEPATILYEDDKVIAFLDKYAHTKGHFLVVPKNYSRNLFSISDED---LS 62

Query: 224 HLLIVARKVATQE--GLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           +L++ AR+ A QE   L  +GF+L+IN+  +  QS++H HVH++
Sbjct: 63  YLIVKAREFALQEIKKLGATGFKLLINNEPDAEQSIFHTHVHII 106


>UniRef50_Q9JN38 Cluster: Putative HIT-like protein; n=2; Mycoplasma
           hominis|Rep: Putative HIT-like protein - Mycoplasma
           hominis
          Length = 106

 Score = 79.0 bits (186), Expect = 3e-14
 Identities = 39/104 (37%), Positives = 65/104 (62%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI+ +EIPAK +YED++ +AF D+ P    H LV  +   + L    D D+Q L 
Sbjct: 3   DDIFEKIITREIPAKIIYEDEKFIAFEDIKPVDKGHFLVTVKNHATNLY---DIDDQTLS 59

Query: 224 HLLIVARKVATQ--EGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            L++ +R++A +  + L  +GF L+IN+  +  Q+V+ +HVH++
Sbjct: 60  SLILKSRELALKRVKELGATGFNLIINNNLSADQTVFRIHVHII 103


>UniRef50_P64382 Cluster: Uncharacterized HIT-like protein HP_0404;
           n=4; Helicobacter|Rep: Uncharacterized HIT-like protein
           HP_0404 - Helicobacter pylori (Campylobacter pylori)
          Length = 104

 Score = 78.6 bits (185), Expect = 4e-14
 Identities = 36/102 (35%), Positives = 61/102 (59%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F KI++ EIP   + E+++ ++F+D+NP+A  H LVIP++ I   +    E   L+  +
Sbjct: 3   VFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPE---LMAQM 59

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGG 355
                +V  + G+ + G++L+ N GKN  Q V HLH H+L G
Sbjct: 60  TSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSG 101


>UniRef50_A6G534 Cluster: HIT-family protein; n=1; Plesiocystis
           pacifica SIR-1|Rep: HIT-family protein - Plesiocystis
           pacifica SIR-1
          Length = 141

 Score = 78.2 bits (184), Expect = 5e-14
 Identities = 42/102 (41%), Positives = 62/102 (60%), Gaps = 1/102 (0%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           T+F KIL  E+P   VYEDDQ +AF D+ P AP H LVIP++  + L +  DE    LG 
Sbjct: 5   TVFDKILDGELPCHRVYEDDQVLAFLDIAPLAPGHTLVIPKQRRAFLHELDDEVAAALGR 64

Query: 227 LL-IVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            L  VAR V    G+ +  + ++ N+G +  Q+V+H+H H++
Sbjct: 65  ALPRVARAVMAATGVPE--YNVLQNNGSSAHQAVFHVHFHII 104


>UniRef50_Q1V185 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein - Candidatus
           Pelagibacter ubique HTCC1002
          Length = 121

 Score = 77.8 bits (183), Expect = 6e-14
 Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 4/111 (3%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQL----SKAGDEDE 211
           + IF KILRKEIP K ++E++  ++FHD++PQ   H LVIP+     L    ++A D++ 
Sbjct: 6   NNIFAKILRKEIPCKKIFENEYVLSFHDISPQKKIHALVIPKGEYIDLDDFNARASDQEI 65

Query: 212 QLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
             L   +    K+         G+R + N  ++G Q V HLH H+ GG ++
Sbjct: 66  IALSKAISEVSKILNISTDTGKGYRALTNLSEDGGQEVPHLHFHLFGGEKV 116


>UniRef50_A5Z767 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 136

 Score = 75.8 bits (178), Expect = 3e-13
 Identities = 42/104 (40%), Positives = 60/104 (57%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI   EIP+  ++EDD+     D  P    H LVIP+   S  +   + D++LL 
Sbjct: 3   DCIFCKIAGGEIPSITLFEDDKVKVIFDAGPATVGHALVIPK---SHAANVFEIDDELLA 59

Query: 224 HLLIVARKVAT--QEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           H  IVA+KVAT  +E     G  ++ N+G+   QSV+HLH+HV+
Sbjct: 60  HAHIVAKKVATALKEATGCEGVNILQNNGEIAGQSVFHLHIHVI 103


>UniRef50_Q74MW7 Cluster: NEQ519; n=1; Nanoarchaeum equitans|Rep:
           NEQ519 - Nanoarchaeum equitans
          Length = 129

 Score = 75.8 bits (178), Expect = 3e-13
 Identities = 37/100 (37%), Positives = 57/100 (57%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI+ KEIPA  VYEDD  +A  D+ P A  H LVIP+K +++L +  +E+ +    L
Sbjct: 3   IFCKIINKEIPAYIVYEDDFVIAILDIYPMAKGHTLVIPKKHVTRLKELSEEEAK---KL 59

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
               +KV  +       + ++IN G    Q + HLH+H++
Sbjct: 60  FAGLKKVIEKIEKISPDYNIIINQGPKAGQEIDHLHIHII 99


>UniRef50_A7D556 Cluster: Histidine triad (HIT) protein; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep: Histidine triad
           (HIT) protein - Halorubrum lacusprofundi ATCC 49239
          Length = 152

 Score = 75.4 bits (177), Expect = 3e-13
 Identities = 42/110 (38%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
 Frame = +2

Query: 26  SAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDE 205
           S+    D IF  I+  +IPA+ V+E D  +AF D NP AP H LVIP+   +     GD 
Sbjct: 7   SSRMSADCIFCSIVDGDIPARTVHETDDVLAFLDANPLAPGHTLVIPK---AHAQHVGDL 63

Query: 206 DEQLLGHLLIVARKVA--TQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           D+ L   L     ++    Q  +D  G  + INDG+   Q V H+HVHV+
Sbjct: 64  DDDLASDLFAAVTELTPRVQAAVDAEGANVGINDGEAAGQEVPHVHVHVI 113


>UniRef50_Q58276 Cluster: Uncharacterized HIT-like protein MJ0866;
           n=1; Methanocaldococcus jannaschii|Rep: Uncharacterized
           HIT-like protein MJ0866 - Methanococcus jannaschii
          Length = 129

 Score = 75.4 bits (177), Expect = 3e-13
 Identities = 37/100 (37%), Positives = 58/100 (58%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI+  EIPAK VYED+  +AF D+NP+   H LV+P+K   +  +    D++L   +
Sbjct: 3   IFCKIINGEIPAKVVYEDEHVLAFLDINPRNKGHTLVVPKKHYERFDEM--PDDELCNFI 60

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
             V + V   + L   G+ +V N+G+   Q V H+H H++
Sbjct: 61  KGVKKTVEVLKKLGFDGYNIVNNNGRVAGQEVNHVHFHII 100


>UniRef50_Q970Y2 Cluster: 141aa long hypothetical histidine triad
           nucleotide-binding protein; n=1; Sulfolobus
           tokodaii|Rep: 141aa long hypothetical histidine triad
           nucleotide-binding protein - Sulfolobus tokodaii
          Length = 141

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 38/101 (37%), Positives = 60/101 (59%), Gaps = 1/101 (0%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI++ EI ++ VYED + +AF D+NP    H+LVIP+     +    D  ++ LG +
Sbjct: 7   IFCKIVKGEIKSQKVYEDQEIMAFLDINPVNKGHVLVIPKDHYENIF---DVPKEKLGKV 63

Query: 230 LIVARKVA-TQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           + V +KVA     +   G  +V N+GK   Q ++HLH+HV+
Sbjct: 64  IEVVQKVAIALRKMGADGVNIVSNNGKAAEQHIFHLHIHVI 104


>UniRef50_Q8PVK5 Cluster: Hit-like protein; n=4;
           Methanosarcinaceae|Rep: Hit-like protein -
           Methanosarcina mazei (Methanosarcina frisia)
          Length = 155

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 39/102 (38%), Positives = 56/102 (54%), Gaps = 2/102 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F KI+  EIP+K VYEDD   AF D+ P +  H L+ P+K  +  +  G ED      L
Sbjct: 10  LFCKIISGEIPSKKVYEDDAVCAFLDIYPASEGHTLIAPKKHFNSFTDMGAED---TARL 66

Query: 230 LIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
              ARK+  A ++     G  + IN+G+   Q V H+HVHV+
Sbjct: 67  FEAARKITAAVEKAFSAEGSNIGINNGEVAGQEVPHVHVHVI 108


>UniRef50_Q1QBU6 Cluster: Histidine triad (HIT) protein; n=2;
           Psychrobacter|Rep: Histidine triad (HIT) protein -
           Psychrobacter cryohalolentis (strain K5)
          Length = 146

 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 38/104 (36%), Positives = 62/104 (59%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF K+L  +IP   VYEDD+ +AF D+ PQA  H+LVIP++    L+   D + +   
Sbjct: 13  DNIFAKMLDGDIPYHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVDLA---DLEPEYAA 69

Query: 224 HLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            +L+ A+KV  A ++  ++ G   +  +G    Q+V+H HVH++
Sbjct: 70  AVLMTAKKVMEAQRQVFNREGIVQMQLNGAEAGQTVFHYHVHLI 113


>UniRef50_UPI00015C430C Cluster: HIT family protein; n=1;
           Streptococcus gordonii str. Challis substr. CH1|Rep: HIT
           family protein - Streptococcus gordonii str. Challis
           substr. CH1
          Length = 173

 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 40/112 (35%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
 Frame = +2

Query: 17  LAKSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPI-SQLSK 193
           LAK      D IF KI+  +IPA  VYED+  +AF D++   P H LV+P++   + L  
Sbjct: 29  LAKEVHFMTDCIFCKIIAGDIPAAKVYEDEAVLAFLDISQVTPGHTLVVPKQHFRNLLDM 88

Query: 194 AGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            G    QL   +  +ARKV   +  D +G  ++ N+ +   Q+V+H HVH++
Sbjct: 89  DGSSSSQLFERVPQIARKV--MKVTDAAGMNIINNNEEIAGQTVFHTHVHLV 138


>UniRef50_Q8YHI2 Cluster: BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE; n=29;
           Proteobacteria|Rep: BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE -
           Brucella melitensis
          Length = 149

 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 42/110 (38%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
 Frame = +2

Query: 26  SAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDE 205
           SA    + IF KILR EIP+  VYE D  VAF DV PQ   H LV+P+ P   L  A  E
Sbjct: 11  SATYDDNNIFAKILRGEIPSTRVYETDSVVAFMDVMPQGKGHTLVVPKAPSRNLLDARPE 70

Query: 206 DEQLLGHLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
               L  ++   +K+  A ++  +  G  ++  +     Q+VYHLH HV+
Sbjct: 71  ---TLADVIQAVQKIANAVKKAFNADGVTVMQFNEPASGQTVYHLHFHVI 117


>UniRef50_Q6A7Y9 Cluster: Putative cell-cycle regulation histidine
           triad protein; n=1; Propionibacterium acnes|Rep:
           Putative cell-cycle regulation histidine triad protein -
           Propionibacterium acnes
          Length = 136

 Score = 69.3 bits (162), Expect = 2e-11
 Identities = 40/104 (38%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F  I   +IPA  +  DD  VAF D+ P    H LVIPR+ ++ +     +D+  LG
Sbjct: 2   DCLFCSIAAGDIPATIIDSDDASVAFLDIEPFQDGHTLVIPRRHVTSVL----DDDGELG 57

Query: 224 HLLIVARKVATQ--EGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            +  +  KVA +  + L  SG  +V N G+   QSV+HLHVHV+
Sbjct: 58  RISPMVTKVARRLVDSLGASGVNVVSNAGEVAGQSVHHLHVHVI 101


>UniRef50_Q4L7E2 Cluster: Hit-like protein involved in cell-cycle
           regulation; n=17; Bacillales|Rep: Hit-like protein
           involved in cell-cycle regulation - Staphylococcus
           haemolyticus (strain JCSC1435)
          Length = 141

 Score = 69.3 bits (162), Expect = 2e-11
 Identities = 37/104 (35%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           +T+F KIL  EIP+  VYEDD   AF D++     H L+IP+K    +    + DE+ + 
Sbjct: 3   ETVFSKILSGEIPSFKVYEDDFVYAFLDISQVTKGHTLLIPKKASPNIF---ETDEETIA 59

Query: 224 HLLIVARKVAT--QEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           H+     KVA   ++  +  G  ++ N+G+   QSV+H+H H L
Sbjct: 60  HIGAALPKVANAIKKAFNPDGLNIIQNNGEFADQSVFHIHFHFL 103


>UniRef50_Q0LZX4 Cluster: Histidine triad (HIT) protein precursor;
           n=2; Alphaproteobacteria|Rep: Histidine triad (HIT)
           protein precursor - Caulobacter sp. K31
          Length = 455

 Score = 68.5 bits (160), Expect = 4e-11
 Identities = 43/101 (42%), Positives = 57/101 (56%), Gaps = 2/101 (1%)
 Frame = +2

Query: 53  FGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLL 232
           F +ILR EI    VYEDDQ +AF D  P  P H+LVI +   S+     +   Q L  ++
Sbjct: 323 FARILRGEIAVPKVYEDDQVLAFMDYAPAEPGHVLVISK--TSKARNLLEISPQDLSRIM 380

Query: 233 IVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            VA +V  A  +GL   GF +V N+G    QSV HLH+HV+
Sbjct: 381 AVAARVGQAQVDGLGVEGFTIVQNNGV--GQSVPHLHIHVI 419


>UniRef50_Q9A5H7 Cluster: HIT family protein; n=6;
           Alphaproteobacteria|Rep: HIT family protein -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 144

 Score = 67.3 bits (157), Expect = 9e-11
 Identities = 38/102 (37%), Positives = 59/102 (57%), Gaps = 2/102 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI+R EIP+  V+EDD+ +AF DV PQ+  H LVI +  +SQ     + + ++L  L
Sbjct: 12  IFAKIIRGEIPSVKVFEDDKVLAFMDVFPQSRGHALVISK--VSQARNLLEVEPEVLADL 69

Query: 230 LIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           +   +K+  AT   L   G  +   +G    Q+++HLH HV+
Sbjct: 70  IAATQKLAKATVTALKPDGVVVTQFNGAPAGQTIFHLHFHVI 111


>UniRef50_Q6YPU5 Cluster: Diadenosine tetraphosphate hydrolase; n=2;
           Candidatus Phytoplasma asteris|Rep: Diadenosine
           tetraphosphate hydrolase - Onion yellows phytoplasma
          Length = 153

 Score = 67.3 bits (157), Expect = 9e-11
 Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 4/118 (3%)
 Frame = +2

Query: 8   EVELAKSAAPGG--DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPIS 181
           +V L+K+   G    TIF KI++K++P   +YED+  VAF D+      H LV+P++   
Sbjct: 2   QVYLSKNTFKGVFMSTIFTKIIKKQVPGYLLYEDNLVVAFLDIAQATKGHTLVVPKQEYR 61

Query: 182 QLSKAGDEDEQLLGHLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            +       E +  HL  V  ++  A  +     G  L+ N+GK   Q+V+H HVH++
Sbjct: 62  DILMM---PEDVFAHLFKVVHQISKALMDVFQAQGINLLNNNGKVAGQTVFHYHVHLI 116


>UniRef50_Q5Z2D6 Cluster: Putative uncharacterized protein; n=1;
           Nocardia farcinica|Rep: Putative uncharacterized protein
           - Nocardia farcinica
          Length = 200

 Score = 67.3 bits (157), Expect = 9e-11
 Identities = 36/104 (34%), Positives = 53/104 (50%), Gaps = 3/104 (2%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           TIF  I+    PA  VYED   +AF D+ P  P H+LV+P+ P   L++    D  + G 
Sbjct: 59  TIFSDIIAGRAPASTVYEDSDVLAFMDIRPMTPGHLLVVPKVPARSLAEL---DPAIGGK 115

Query: 227 LLIVARKVATQEGLDK---SGFRLVINDGKNGAQSVYHLHVHVL 349
           L  V +K+A      +    G    + DG    Q V+H+H+HV+
Sbjct: 116 LFQVGQKLAAALRASEVACDGVNFFLADGVAAGQEVFHVHLHVI 159


>UniRef50_Q03WU6 Cluster: Diadenosine tetraphosphate (Ap4A)
           hydrolase related HIT family hydrolase; n=1; Leuconostoc
           mesenteroides subsp. mesenteroides ATCC 8293|Rep:
           Diadenosine tetraphosphate (Ap4A) hydrolase related HIT
           family hydrolase - Leuconostoc mesenteroides subsp.
           mesenteroides (strain ATCC 8293 /NCDO 523)
          Length = 140

 Score = 66.9 bits (156), Expect = 1e-10
 Identities = 36/102 (35%), Positives = 60/102 (58%), Gaps = 2/102 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDED-EQLLGH 226
           IF KI+  EIP+  VYED+  +AF D++   P H LV+P+K +  +    DE  +++L  
Sbjct: 3   IFDKIIAGEIPSYKVYEDEDVLAFLDISQVTPGHTLVVPKKNVDNIFDYDDETAKKVLLK 62

Query: 227 LLIVARKVATQEGLDK-SGFRLVINDGKNGAQSVYHLHVHVL 349
           L ++AR +   +  DK +G  +  N+G +  Q+V H H H++
Sbjct: 63  LPVIARAIKASD--DKITGLNVQSNNGPSAGQTVIHSHWHLI 102


>UniRef50_Q5Z134 Cluster: Putative uncharacterized protein; n=1;
           Nocardia farcinica|Rep: Putative uncharacterized protein
           - Nocardia farcinica
          Length = 150

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 40/108 (37%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F +I+    PA  VYED+   AF D+ P A  H LVIP++  + L    D D +L  
Sbjct: 7   DCVFCRIVAGAAPATKVYEDETLCAFLDIRPIARGHTLVIPKRHAAGLP---DLDPELGA 63

Query: 224 HLLIVARKVA---TQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGR 358
            +   A ++A    + GL   G  LV+NDG+   Q+V H+H+HV+  R
Sbjct: 64  AMFRAAHRIALAMRRGGLAADGANLVLNDGRAAFQTVGHVHLHVIPRR 111


>UniRef50_Q8EW55 Cluster: Histidine triad protein HIT; n=1;
           Mycoplasma penetrans|Rep: Histidine triad protein HIT -
           Mycoplasma penetrans
          Length = 145

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 38/105 (36%), Positives = 55/105 (52%), Gaps = 3/105 (2%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F KI+ KEIP+  V E+   +AF D++P +  H LVIP+K    L      DE  L 
Sbjct: 8   DCLFCKIVNKEIPSNIVDENAYALAFLDISPASDGHTLVIPKKHCIDLVHC---DELYLK 64

Query: 224 HLLIVARKVA---TQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
             + +A+KVA       L   GF  + N G    Q ++H H+HV+
Sbjct: 65  ETISLAKKVADTIESSSLKPWGFNFLSNQGSIAGQVIFHFHLHVI 109


>UniRef50_A0LM74 Cluster: Histidine triad (HIT) protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Histidine triad
           (HIT) protein - Syntrophobacter fumaroxidans (strain DSM
           10017 / MPOB)
          Length = 136

 Score = 65.7 bits (153), Expect = 3e-10
 Identities = 34/104 (32%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF +I++ ++P   +YEDD+ ++F D+NP A  H LV+P++  S L     ED   L 
Sbjct: 3   DCIFCQIIQGQLPCARIYEDDRVLSFLDINPVARGHALVVPKRHYSTLFHIPPED---LE 59

Query: 224 HLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
             ++ A++V  A  +G+  SG  ++ N+ +   Q + H H+H++
Sbjct: 60  ACIVAAKRVGAAVFKGVGASGLNVLQNNYRAAGQLIDHFHLHLI 103


>UniRef50_Q89JY4 Cluster: Blr5135 protein; n=15;
           Alphaproteobacteria|Rep: Blr5135 protein -
           Bradyrhizobium japonicum
          Length = 142

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           + IF KILR E P   VYED+   AF D+ P+ P H LVIP+ P   +     +D     
Sbjct: 7   NNIFAKILRGEFPCHKVYEDEHVFAFLDIMPRVPGHTLVIPKAPARNILDIKPDD---YA 63

Query: 224 HLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           H+   A ++  A  +     G  +   +   G Q V+HLH+HVL
Sbjct: 64  HVARGAHRISAAAMKAFKADGITVQQFNEPAGGQVVFHLHMHVL 107


>UniRef50_A5UPG3 Cluster: Histidine triad (HIT) protein; n=5;
           Chloroflexi (class)|Rep: Histidine triad (HIT) protein -
           Roseiflexus sp. RS-1
          Length = 138

 Score = 64.5 bits (150), Expect = 6e-10
 Identities = 35/103 (33%), Positives = 58/103 (56%), Gaps = 2/103 (1%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           ++F +I+  E+P+  VYEDD+ +AF D+NP +  H LVI ++    +         L+  
Sbjct: 3   SVFSRIVSGELPSAKVYEDDETLAFMDINPASRGHTLVICKEEHPDIFTT---PPHLVAA 59

Query: 227 LLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           +   A+KV  A ++ LD  G  +V N+G    Q V+H HVH++
Sbjct: 60  VARTAQKVALALRDALDIDGLNIVQNNGAAAGQVVFHYHVHLI 102


>UniRef50_A1RYX9 Cluster: Histidine triad (HIT) protein; n=1;
           Thermofilum pendens Hrk 5|Rep: Histidine triad (HIT)
           protein - Thermofilum pendens (strain Hrk 5)
          Length = 139

 Score = 64.1 bits (149), Expect = 8e-10
 Identities = 35/104 (33%), Positives = 56/104 (53%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F +I+R ++ A FVY   + V F D  P    H LV+P+     +  A  +   +L 
Sbjct: 3   DCVFCRIVRGQLDAHFVYVGGRVVVFLDKYPVTRGHALVVPKDHYRDVFDAPGD---VLS 59

Query: 224 HLLIVARKVAT--QEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            ++ VA+ VA   +E L   G RLV+N G+   Q ++H H+HV+
Sbjct: 60  EMVFVAKVVALAQREALGARGVRLVMNSGREAGQEIFHAHMHVI 103


>UniRef50_A4FZK6 Cluster: Histidine triad (HIT) protein; n=5;
           Methanococcus|Rep: Histidine triad (HIT) protein -
           Methanococcus maripaludis
          Length = 130

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 32/101 (31%), Positives = 58/101 (57%), Gaps = 1/101 (0%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF  I++ +IPA+ +YEDD+ +AF D  P+A  H L+IP++      +     ++L   +
Sbjct: 3   IFCDIVKGDIPARIIYEDDKFLAFMDAFPRAVGHTLIIPKEHFETFDEL---PKELACEM 59

Query: 230 LIVARKVATQ-EGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           + V  K+  + E L+  G+ L+ N+ +   Q V H+H H++
Sbjct: 60  MAVIHKIVKKLEKLEMDGYNLLNNNKQVSGQEVPHVHFHII 100


>UniRef50_A3HAI2 Cluster: Histidine triad (HIT) protein; n=2;
           Thermoprotei|Rep: Histidine triad (HIT) protein -
           Caldivirga maquilingensis IC-167
          Length = 151

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 37/104 (35%), Positives = 56/104 (53%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           + IF +I+ +E P   VYEDD  +A  D  P    HILV+P++    + +   E    L 
Sbjct: 3   ECIFCRIIGREAPGHVVYEDDDVIAILDKYPINKGHILVMPKRHYRDIFEIPPE---ALC 59

Query: 224 HLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            ++ VA+ +  A   GL   G RL+ N+G +  Q V+H HVHV+
Sbjct: 60  KVMKVAKLMARAVVNGLKADGVRLIQNNGPSAGQVVFHFHVHVI 103


>UniRef50_Q74I95 Cluster: Hit protein; n=5; Lactobacillus|Rep: Hit
           protein - Lactobacillus johnsonii
          Length = 144

 Score = 63.3 bits (147), Expect = 1e-09
 Identities = 33/106 (31%), Positives = 58/106 (54%), Gaps = 1/106 (0%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDED-EQLL 220
           D +F KI+R EIP+  V+E+D   AF D++     H L+IP+K +        ED  + L
Sbjct: 7   DCLFCKIIRGEIPSYTVFENDDVKAFLDISQVTKGHTLIIPKKHLVNFFDYSQEDAARFL 66

Query: 221 GHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGR 358
            ++ ++A+ +   +   K G  + +N+G+   Q V H H+H++  R
Sbjct: 67  QYIPVIAQAIKKSDPTIK-GLNVEVNNGEIAGQVVMHSHIHLIPRR 111


>UniRef50_Q8ZTP1 Cluster: HIT family protein; n=4; Pyrobaculum|Rep:
           HIT family protein - Pyrobaculum aerophilum
          Length = 137

 Score = 63.3 bits (147), Expect = 1e-09
 Identities = 39/111 (35%), Positives = 55/111 (49%), Gaps = 2/111 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI+R E PA  VYED++ V   D  P +  H+LV+ +K  + +  A    E    
Sbjct: 2   DCIFCKIIRGEAPAWKVYEDEEFVVILDKYPASYGHVLVVSKKHFTNIVDA--PVELSAR 59

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL--GGRQLEW 370
              I  R       L   G  +V N G++  Q+V+HLH+HV+   G  L W
Sbjct: 60  GFEIAIRLAKAWAKLGAPGVNIVTNAGRSAGQAVFHLHIHVIPRWGDPLRW 110


>UniRef50_Q672P8 Cluster: Histidine triad family protein precursor;
           n=3; Magnoliophyta|Rep: Histidine triad family protein
           precursor - Solanum lycopersicum (Tomato) (Lycopersicon
           esculentum)
          Length = 150

 Score = 62.9 bits (146), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 1/97 (1%)
 Frame = +2

Query: 62  ILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLL-IV 238
           I+R++ PA  VYEDD C+   D NP    H LVIP+   + L +        +   L ++
Sbjct: 2   IVRRKTPALKVYEDDVCLCILDANPLCFGHSLVIPKSHFTSLQETPSSVVAAMSSKLPLI 61

Query: 239 ARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           +  V    G D   F L++N+G    Q +YH H+H++
Sbjct: 62  SSAVMKATGCD--SFNLLVNNGAAAGQVIYHTHIHII 96


>UniRef50_Q88X03 Cluster: Cell-cycle regulation histidine triad
           protein; n=26; Bacilli|Rep: Cell-cycle regulation
           histidine triad protein - Lactobacillus plantarum
          Length = 150

 Score = 62.5 bits (145), Expect = 3e-09
 Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQL-SKAGDEDEQLL 220
           D IF KI++ +IP+  VYEDD   AF D++   P H LV+P+  ++ +     D    + 
Sbjct: 11  DCIFCKIIKGDIPSYTVYEDDMVKAFLDISQGTPGHTLVVPKTHVADIFGYDRDLASIVF 70

Query: 221 GHLLIVARKV-ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
             +  +AR + AT E +   G  +V N+G    QSV+H H H++
Sbjct: 71  ARIPEIARAIKATDENI--IGMNIVNNNGAVAYQSVFHSHFHLI 112


>UniRef50_Q6MTB0 Cluster: Histidine triad protein; n=2;
           Mycoplasma|Rep: Histidine triad protein - Mycoplasma
           mycoides subsp. mycoides SC
          Length = 132

 Score = 62.5 bits (145), Expect = 3e-09
 Identities = 31/104 (29%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F KI+ +EIP+  +YE++   +F DV P +  H+L+IP+K     S     D++ L 
Sbjct: 2   DCLFCKIINQEIPSYKIYENEYVYSFLDVRPVSNGHLLIIPKKHFENFSAC---DDKYLQ 58

Query: 224 HLLIVARKVAT--QEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            +++  + +    +E L+ +GF  + N+     Q+V H H H++
Sbjct: 59  EVILAKKHLVNLLKEKLNPAGFNYLSNEQAISGQTVLHYHEHIM 102


>UniRef50_Q4K6N7 Cluster: HIT family protein; n=1; Pseudomonas
           fluorescens Pf-5|Rep: HIT family protein - Pseudomonas
           fluorescens (strain Pf-5 / ATCC BAA-477)
          Length = 158

 Score = 62.5 bits (145), Expect = 3e-09
 Identities = 31/100 (31%), Positives = 52/100 (52%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF +I    +PA  VY D+ C+AF DV+P    H+L+IP++ + +L +      Q L  +
Sbjct: 4   IFCQIAAGTLPAALVYRDEHCMAFMDVHPLGEGHLLLIPQQHVEKLEQLPGFIRQHLYQV 63

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
                    + G    G  L++NDG+   Q + H H+H++
Sbjct: 64  FDGLLAAQRRAGYGVEGTHLLVNDGRATNQHIPHAHLHLI 103


>UniRef50_A6FJ37 Cluster: Histidine triad (HIT) protein; n=1;
           Moritella sp. PE36|Rep: Histidine triad (HIT) protein -
           Moritella sp. PE36
          Length = 147

 Score = 62.5 bits (145), Expect = 3e-09
 Identities = 36/108 (33%), Positives = 54/108 (50%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           + IF KILR E+P   VYED+  +AF D+ PQ   H LVIP++    +    DE      
Sbjct: 8   NNIFAKILRAELPCIKVYEDEYTLAFMDIMPQMAGHTLVIPKESAVTIYDLSDEAAMACM 67

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLE 367
             + +    A ++ +   G  +  ++G    Q+V H H HVL G  L+
Sbjct: 68  RTVKLIGS-AVEKAVGFGGSTVFQHNGVKAGQTVPHFHFHVLPGSILD 114


>UniRef50_P94252 Cluster: Uncharacterized HIT-like protein BB_0379;
           n=4; Borrelia burgdorferi group|Rep: Uncharacterized
           HIT-like protein BB_0379 - Borrelia burgdorferi (Lyme
           disease spirochete)
          Length = 139

 Score = 62.5 bits (145), Expect = 3e-09
 Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDE-DEQLL 220
           D IF KI+ KE+P+  VYEDD  +AF D+NP    H LVIP++    L    D+ +E++L
Sbjct: 3   DCIFCKIINKELPSYKVYEDDLVLAFLDINPLTVGHTLVIPKEHSESLLNMDDKFNERVL 62

Query: 221 GHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
                ++  +         G  +    G    Q V+H H HV+
Sbjct: 63  KVCKKISNALKRINSSIYGGINIYSALGAGAGQEVFHTHFHVI 105


>UniRef50_Q39B39 Cluster: Histidine triad (HIT) protein; n=32;
           Proteobacteria|Rep: Histidine triad (HIT) protein -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 143

 Score = 62.1 bits (144), Expect = 3e-09
 Identities = 35/99 (35%), Positives = 52/99 (52%)
 Frame = +2

Query: 53  FGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLL 232
           F KILR E+P   V EDD  +A  D+ PQA  H+LVIP++P +Q+ +    D    G  +
Sbjct: 13  FAKILRGELPCVKVAEDDATLAIMDLMPQADGHVLVIPKEPAAQIFELSG-DAAAAGIRM 71

Query: 233 IVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
                 A +  L+  G  +   +G    Q+V H+H HV+
Sbjct: 72  TQRVAAAVRAALEPDGVFIGQFNGAAAGQTVPHVHFHVI 110


>UniRef50_Q1NGF8 Cluster: HIT family protein; n=8;
           Proteobacteria|Rep: HIT family protein - Sphingomonas
           sp. SKA58
          Length = 146

 Score = 62.1 bits (144), Expect = 3e-09
 Identities = 33/102 (32%), Positives = 59/102 (57%), Gaps = 2/102 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF  IL+ +IP+  +YED   ++F D+ PQ   H LVI +   S+     + +++ L  +
Sbjct: 12  IFALILQGKIPSTALYEDADTLSFLDIMPQTRGHALVISK--WSKARNLLEMEDKALAQV 69

Query: 230 LIVARKVAT--QEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           +   +KVAT  ++ L+  G ++   +G    Q+++HLHVH+L
Sbjct: 70  MATTKKVATAIRKALNPDGIQIAQFNGAPAGQTIFHLHVHIL 111


>UniRef50_Q7R1Q2 Cluster: GLP_28_16821_16420; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_28_16821_16420 - Giardia lamblia
           ATCC 50803
          Length = 133

 Score = 62.1 bits (144), Expect = 3e-09
 Identities = 31/100 (31%), Positives = 54/100 (54%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF  I+ +++P++ VYED+  +AF D+ P AP H +VIP+   +   +        LG  
Sbjct: 3   IFCSIVARDVPSEAVYEDEHVLAFLDIMPSAPGHCVVIPKYHAALFHELPPASAAALGAA 62

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           L+     A  + ++ S + +V N+G    Q V H+H H++
Sbjct: 63  LVKV-SGALIKAMECSCYNIVNNNGPEAGQEVPHVHFHII 101


>UniRef50_Q4DJ40 Cluster: Adenosine 5'-monophosphoramidase,
           putative; n=6; Trypanosomatidae|Rep: Adenosine
           5'-monophosphoramidase, putative - Trypanosoma cruzi
          Length = 141

 Score = 62.1 bits (144), Expect = 3e-09
 Identities = 33/103 (32%), Positives = 54/103 (52%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI+   IP   V E  + +AF D+NP +  H+L++P+     L +   E    LG +
Sbjct: 5   IFCKIVEGSIPCHRVAETARVLAFVDINPLSRGHLLIVPKAHAEFLHQVEPETAADLGVM 64

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGR 358
           +    +V   EG  K+ + ++ N+GK   Q V H+H H++  R
Sbjct: 65  MAKIARVVAGEGEPKTQYNVLQNNGKLAHQEVPHVHFHIIPKR 107


>UniRef50_O07513 Cluster: Protein hit; n=16; Bacillaceae|Rep:
           Protein hit - Bacillus subtilis
          Length = 145

 Score = 62.1 bits (144), Expect = 3e-09
 Identities = 34/101 (33%), Positives = 57/101 (56%), Gaps = 1/101 (0%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI+  +IP+  VYED+  +AF D++     H LVIP+  I  + +  DE  +   H 
Sbjct: 8   IFCKIIAGDIPSAKVYEDEHVLAFLDISQVTKGHTLVIPKTHIENVYEFTDELAKQYFHA 67

Query: 230 L-IVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           +  +AR  A ++  +  G   + N+G+   QSV+H H+H++
Sbjct: 68  VPKIAR--AIRDEFEPIGLNTLNNNGEKAGQSVFHYHMHII 106


>UniRef50_Q6F1M1 Cluster: Putative nucleotidyl
           hydrolase/transferase; n=2; Entomoplasmatales|Rep:
           Putative nucleotidyl hydrolase/transferase - Mesoplasma
           florum (Acholeplasma florum)
          Length = 135

 Score = 61.7 bits (143), Expect = 4e-09
 Identities = 34/102 (33%), Positives = 51/102 (50%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI+++EIP+  +YE++   AF D+NP +  H LVIP+     LS   D     + 
Sbjct: 3   DCIFCKIIKQEIPSYKIYENEYVYAFLDINPVSDGHALVIPKVHAENLSTTPDLYLSEVS 62

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
               V  ++  ++     GF  V N      Q V+H H H+L
Sbjct: 63  KAKKVVAQILQEKLKGVKGFNYVSNQEAIAKQVVFHYHEHIL 104


>UniRef50_A1WAF8 Cluster: Histidine triad (HIT) protein; n=5;
           Betaproteobacteria|Rep: Histidine triad (HIT) protein -
           Acidovorax sp. (strain JS42)
          Length = 143

 Score = 61.7 bits (143), Expect = 4e-09
 Identities = 36/108 (33%), Positives = 57/108 (52%), Gaps = 2/108 (1%)
 Frame = +2

Query: 32  APGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDE 211
           +P G  IF +++  EIP+  VYED   +AF D+    P H+LV  ++  + L     E+ 
Sbjct: 6   SPPGQCIFCRLVAGEIPSAKVYEDALTIAFMDIGQVTPGHVLVATKRHAATLLDTTPEE- 64

Query: 212 QLLGHLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
                L+  AR+V  A +   D  G  L+  +G  G Q+V H+H+HV+
Sbjct: 65  --AAALMQTARRVALAVRTAFDPPGLTLLQANGALGGQTVAHVHLHVV 110


>UniRef50_Q97S70 Cluster: HIT family protein; n=37;
           Streptococcaceae|Rep: HIT family protein - Streptococcus
           pneumoniae
          Length = 136

 Score = 61.3 bits (142), Expect = 6e-09
 Identities = 36/103 (34%), Positives = 56/103 (54%), Gaps = 1/103 (0%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKA-GDEDEQLL 220
           D IF KI+  EIPA  VYED+Q +AF D++     H LV+P++    L +       QL 
Sbjct: 3   DCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPKEHYRNLLEMDATSASQLF 62

Query: 221 GHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
             +  VA+KV   +    +G  ++ N  +   Q+V+H HVH++
Sbjct: 63  AQVPKVAQKV--MKVTKAAGMNIISNCEEVAGQTVFHTHVHLV 103


>UniRef50_Q1FG87 Cluster: Histidine triad (HIT) protein; n=5;
           Clostridiales|Rep: Histidine triad (HIT) protein -
           Clostridium phytofermentans ISDg
          Length = 138

 Score = 61.3 bits (142), Expect = 6e-09
 Identities = 34/102 (33%), Positives = 57/102 (55%), Gaps = 2/102 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF K+   E  +  VYEDD   A  D++P +  H L++P+K  + L +    +E  +   
Sbjct: 7   IFCKLASGEFQSATVYEDDLFRAILDISPASKGHTLLLPKKHAANLFEL---EEPEVSRA 63

Query: 230 LIVARK--VATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           L VA+K  +A Q+ L+  G  ++ N+G    QSV+H H+H++
Sbjct: 64  LSVAKKLAIAIQKTLNCDGINILQNNGTAAGQSVFHFHIHLI 105


>UniRef50_A7R099 Cluster: Chromosome undetermined scaffold_300,
           whole genome shotgun sequence; n=4; core
           eudicotyledons|Rep: Chromosome undetermined
           scaffold_300, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 195

 Score = 61.3 bits (142), Expect = 6e-09
 Identities = 32/115 (27%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
 Frame = +2

Query: 17  LAKSAAPGGDT---IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQL 187
           +  S +  G T   +F KI+R + PA  +YEDD C+   D +P +  H L+IP+   S L
Sbjct: 28  ICASGSENGQTNFCVFCKIIRGQSPALKLYEDDMCLCILDTHPLSHGHSLIIPKSHFSSL 87

Query: 188 SKAGDE-DEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
                     +   +  ++  +    G D   F L++N+G    Q ++H H+H++
Sbjct: 88  EMTPPSVVAAMCSKVPFISNAIMKATGCD--SFNLLVNNGAAAGQVIFHTHIHII 140


>UniRef50_A5EX58 Cluster: Histidine triad (HIT) domain protein; n=1;
           Dichelobacter nodosus VCS1703A|Rep: Histidine triad
           (HIT) domain protein - Dichelobacter nodosus (strain
           VCS1703A)
          Length = 137

 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 32/104 (30%), Positives = 60/104 (57%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           DTIF KILR EIP+  +YE++   +F D  PQ+  H L+I ++    L +  D   + L 
Sbjct: 3   DTIFHKILRAEIPSAKIYENEFIYSFMDAFPQSQGHALIIAKEGGKNLLEMND---RALS 59

Query: 224 HLLIVARKVATQEG--LDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            +++ ++K+AT +       G +++  +G    Q+V++ H+H++
Sbjct: 60  EIILFSKKLATAQWNVFQPDGIKVMQFNGAAAGQTVFYYHMHLI 103


>UniRef50_Q5UZ82 Cluster: Histidine triad protein; n=4;
           Halobacteriaceae|Rep: Histidine triad protein -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 142

 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF +I+  +IP + VYEDD  +AF D NP +P H LVIP+    +L+   D    +  
Sbjct: 4   DCIFCQIVAGDIPGRTVYEDDTVLAFLDANPLSPGHTLVIPKAHHERLN---DTPADVAS 60

Query: 224 HLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            ++    ++  A +  +D     +  N+G+   Q V H+H H++
Sbjct: 61  AVMSTLHELVPAVESAVDAPASTVAFNNGEVAGQEVPHVHGHII 104


>UniRef50_A4XT81 Cluster: Histidine triad (HIT) protein; n=7;
           Pseudomonas aeruginosa group|Rep: Histidine triad (HIT)
           protein - Pseudomonas mendocina ymp
          Length = 148

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F  I   ++PA  +YED+  +   D+ P  P H+L++ R     L    D        L
Sbjct: 4   VFCAIAAGQLPAHKLYEDEDFIVLLDIFPMRPAHVLIVSRVHAPYLK---DLPAAARERL 60

Query: 230 LIVARKVATQ---EGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWP 373
           L +A KVA      G  + G  L+INDG +  Q V HLH+H++  R+ + P
Sbjct: 61  LALADKVAAALRVAGHGREGINLLINDGPDSNQHVPHLHLHLIPRRRGDLP 111


>UniRef50_Q9KDM3 Cluster: Hit-like protein involved in cell-cycle
           regulation; n=7; Bacilli|Rep: Hit-like protein involved
           in cell-cycle regulation - Bacillus halodurans
          Length = 142

 Score = 59.7 bits (138), Expect = 2e-08
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 2/102 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI+  EIP+  VYEDD   AF D++     H LVIP+          +  E++   L
Sbjct: 8   IFCKIIAGEIPSATVYEDDHVYAFLDISQVTKGHTLVIPK---VHKRNVFELSEEIASSL 64

Query: 230 LIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
                K+  A  +     G  +V N+G+   Q+V+H H+H+L
Sbjct: 65  FAAVPKISRAINDAFQPIGMNIVNNNGEAAGQTVFHYHLHLL 106


>UniRef50_Q3W573 Cluster: Histidine triad (HIT) protein; n=3;
           Actinomycetales|Rep: Histidine triad (HIT) protein -
           Frankia sp. EAN1pec
          Length = 148

 Score = 59.7 bits (138), Expect = 2e-08
 Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 3/104 (2%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           + +F  I+ +   A  ++EDD  +AF D  P  P H+LVIP+     L    D DE++  
Sbjct: 9   ECVFCAIVHRGTAASIIHEDDTALAFMDHRPVTPGHLLVIPKAHAVGLE---DLDERVGT 65

Query: 224 HLLIVARKVA---TQEGLDKSGFRLVINDGKNGAQSVYHLHVHV 346
            + +VA ++     + GL   G  L + DG+   Q ++H+H+HV
Sbjct: 66  QVWLVAHRLGRALRRSGLRCEGVNLFLADGEAAFQEIFHVHLHV 109


>UniRef50_Q0VNN6 Cluster: HIT family protein; n=1; Alcanivorax
           borkumensis SK2|Rep: HIT family protein - Alcanivorax
           borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
          Length = 150

 Score = 59.7 bits (138), Expect = 2e-08
 Identities = 38/108 (35%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           + IF +I    +PA  VYEDD  +   D+ P    H LVIPR+  S L      D  +  
Sbjct: 3   ECIFCQIQAGTLPASVVYEDDLALVILDLFPIREAHCLVIPRQHESLLEGL---DAAVTH 59

Query: 224 HLLIVARKVATQE---GLDKSGFRLVINDGKNGAQSVYHLHVHVLGGR 358
            L+ +AR+    +   GL      +V+NDG+   Q V H+HVHV+  R
Sbjct: 60  RLMDLARRTIVAQKRAGLAVKAHNVVVNDGREANQHVPHVHVHVIPRR 107


>UniRef50_Q7NAX8 Cluster: Hit-like; n=1; Mycoplasma
           gallisepticum|Rep: Hit-like - Mycoplasma gallisepticum
          Length = 146

 Score = 59.3 bits (137), Expect = 2e-08
 Identities = 30/100 (30%), Positives = 49/100 (49%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F KI+  EI A  V ++D  +AF D  P +  H LVIP+K     S+   E+   +  L
Sbjct: 17  VFCKIINNEIQAHVVAQNDLAIAFLDAFPVSNGHTLVIPKKHHQDFSRTPKEEMHAVTDL 76

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
                K+  +  L+  G+  + N      Q V+H H+H++
Sbjct: 77  AQEVVKLLDRSDLNVHGYNYLSNQASIAGQEVFHFHLHII 116


>UniRef50_P75504 Cluster: Uncharacterized 16.1 kDa HIT-like protein;
           n=2; Mycoplasma|Rep: Uncharacterized 16.1 kDa HIT-like
           protein - Mycoplasma pneumoniae
          Length = 144

 Score = 59.3 bits (137), Expect = 2e-08
 Identities = 34/109 (31%), Positives = 52/109 (47%)
 Frame = +2

Query: 23  KSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGD 202
           K +    + IF  I+   + +  V E++   AF D  P A  H LVIP+K     S   D
Sbjct: 4   KQSMANNNCIFCGIVEGNVKSFKVGENEHAFAFLDAFPVADGHTLVIPKKHAVNYSSTDD 63

Query: 203 EDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           E  + +  LL     +  Q+ L  +G   V+N+G    Q V+H H+HV+
Sbjct: 64  ESLKAVS-LLAKEMALKLQQRLQPAGLNYVVNEGAKAGQEVFHYHMHVV 111


>UniRef50_UPI00015B4104 Cluster: PREDICTED: hypothetical protein;
           n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
           protein - Nasonia vitripennis
          Length = 144

 Score = 58.0 bits (134), Expect = 5e-08
 Identities = 32/100 (32%), Positives = 49/100 (49%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F KIL+KE P   +YEDD      D+NP +  H L+IP+  I        E E+L   +
Sbjct: 12  VFCKILKKEEPGVNIYEDDHVACIKDINPASDHHYLIIPKNHIVNAKVLNKEHEELYDKM 71

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           +     +  + GL K+  R   +       +V HLH+HV+
Sbjct: 72  VATVDTIVDKLGLVKNSTRTGFH--WPPFTTVGHLHLHVI 109


>UniRef50_A6PM84 Cluster: Histidine triad (HIT) protein; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Histidine triad
           (HIT) protein - Victivallis vadensis ATCC BAA-548
          Length = 142

 Score = 58.0 bits (134), Expect = 5e-08
 Identities = 37/105 (35%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
 Frame = +2

Query: 41  GDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLL 220
           G+ IF KI   EIPA  +YED+  +AF D+ P    H LVIP++     S      E   
Sbjct: 2   GNCIFCKIAAGEIPAVKIYEDELVLAFLDIGPINFGHTLVIPKEHHESSSTI---PEATA 58

Query: 221 GHLLIVARK--VATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           G +  +  +  +A +  LD   F L + DG    Q V H H+HV+
Sbjct: 59  GRMFHIGSRIGIALRRELDYDAFNLHLADGTAAGQVVPHAHLHVV 103


>UniRef50_Q023M8 Cluster: Histidine triad (HIT) protein; n=2;
           Bacteria|Rep: Histidine triad (HIT) protein - Solibacter
           usitatus (strain Ellin6076)
          Length = 146

 Score = 57.6 bits (133), Expect = 7e-08
 Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 2/111 (1%)
 Frame = +2

Query: 35  PGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQ 214
           P    +F +I    +PA  VYE ++ VAF D  P  P H L+IPR     L++     E 
Sbjct: 6   PSAKCVFCQIAAGTLPAAVVYETEELVAFLDTRPLFPGHCLLIPRPHFETLTEL---PED 62

Query: 215 LLGHLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQ 361
            +  L   AR +  A +   D  G  + IN+    +QSV HLHVH++  R+
Sbjct: 63  RVTPLFAAARMLTSAVETAFDAEGSFVAINN--RVSQSVPHLHVHIVPRRR 111


>UniRef50_A6FN65 Cluster: HIT family protein; n=1; Roseobacter sp.
           AzwK-3b|Rep: HIT family protein - Roseobacter sp.
           AzwK-3b
          Length = 332

 Score = 57.6 bits (133), Expect = 7e-08
 Identities = 27/96 (28%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
 Frame = +2

Query: 74  EIPA-KFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKV 250
           E+P  + V E++ CVA  D  P  P H L+IP++ ++        +   +  +L+  R+ 
Sbjct: 216 ELPTQRIVAENELCVAIRDGFPVTPMHTLIIPKRHVADYFDLYQPELNAIQTMLVEQRRQ 275

Query: 251 ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGR 358
            T       GF + +N G +  Q+++H+HVH++  R
Sbjct: 276 ITAADDTVKGFNVGVNAGSDAGQTIFHVHVHLIPRR 311


>UniRef50_P95937 Cluster: Uncharacterized HIT-like protein SSO2163;
           n=2; Sulfolobus|Rep: Uncharacterized HIT-like protein
           SSO2163 - Sulfolobus solfataricus
          Length = 139

 Score = 57.2 bits (132), Expect = 9e-08
 Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF  I+        VY +D+ VAF D  P  P H LV+PR       +     E ++ +L
Sbjct: 3   IFCNIVEGRDHGYIVYSNDRVVAFLDKFPITPGHTLVVPRTHYENFLEIS---EDVIPYL 59

Query: 230 LIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
               RK+  A ++ L   G R++ N GK+  Q V+H H H++
Sbjct: 60  CTAVRKISIAVKKALKADGIRILTNIGKSAGQVVFHSHFHIV 101


>UniRef50_Q11066 Cluster: Uncharacterized HIT-like protein
           Rv1262c/MT1300; n=17; Mycobacterium|Rep: Uncharacterized
           HIT-like protein Rv1262c/MT1300 - Mycobacterium
           tuberculosis
          Length = 144

 Score = 57.2 bits (132), Expect = 9e-08
 Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F  I+  E PA  +YED   +A  D+ P    H LV+P++    L+   D   + L  +
Sbjct: 4   VFCAIIAGEAPAIRIYEDGGYLAILDIRPFTRGHTLVLPKRHTVDLT---DTPPEALADM 60

Query: 230 LIVARKVATQEGLDK--SGFRLVINDGKNGAQSVYHLHVHVLGGR 358
           + + +++A      K      + INDG+   Q+V+H+H+HVL  R
Sbjct: 61  VAIGQRIARAARATKLADATHIAINDGRAAFQTVFHVHLHVLPPR 105


>UniRef50_UPI000155C234 Cluster: PREDICTED: similar to
           PKCI-Z-related protein; n=1; Ornithorhynchus
           anatinus|Rep: PREDICTED: similar to PKCI-Z-related
           protein - Ornithorhynchus anatinus
          Length = 109

 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 23/37 (62%), Positives = 30/37 (81%)
 Frame = +2

Query: 107 QCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQL 217
           QC+AFHDV PQAP H LVIP+KPI ++++A D DE +
Sbjct: 38  QCLAFHDVAPQAPVHFLVIPKKPIVRMAEAEDADENV 74


>UniRef50_A7BDL4 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 148

 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 33/101 (32%), Positives = 49/101 (48%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           TIF  I+    P +FV+ DD CVAF  + P +P H+LV+PR      +   D    +  H
Sbjct: 3   TIFDNIITGVWPGRFVWADDVCVAFATIEPTSPGHVLVVPRTAYDAWT---DAPSDVAAH 59

Query: 227 LLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           L+ VAR +   +   K+ F +           V H H+HV+
Sbjct: 60  LMTVARTIGLAQ---KAAFGVPRAGLAIAGFEVPHTHLHVI 97


>UniRef50_A1VGI9 Cluster: Histidine triad (HIT) protein; n=2;
           Desulfovibrio vulgaris subsp. vulgaris|Rep: Histidine
           triad (HIT) protein - Desulfovibrio vulgaris subsp.
           vulgaris (strain DP4)
          Length = 139

 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KI+R EIP   +Y DD  ++F D+ P    H LV+PR+     +   D   +L  
Sbjct: 5   DCIFCKIIRGEIPCAQLYADDHVISFMDIGPVKRGHALVVPRE---HHATVFDMPAELGA 61

Query: 224 HLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           H++  A++V  A        G  +  N+     Q V+H+H H++
Sbjct: 62  HVMGAAQRVGRAIMAATGAEGLNIFQNNFAAAGQVVFHVHWHLI 105


>UniRef50_Q5KLA4 Cluster: Hydrolase, putative; n=2; Dikarya|Rep:
           Hydrolase, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 140

 Score = 56.4 bits (130), Expect = 2e-07
 Identities = 33/100 (33%), Positives = 55/100 (55%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI++ EIP+  + E +   AF DV P A  H LVIP++  +  ++  DE    +  +
Sbjct: 8   IFCKIIKGEIPSMKLLETESVFAFMDVGPIARGHCLVIPKQHAATFTELPDE---AMVDI 64

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           L   +K+A   G +   + ++ N+G+   Q V H+H HV+
Sbjct: 65  LPTCKKLAAATGAE--NYNILQNNGRPAHQVVDHVHFHVI 102


>UniRef50_P49774 Cluster: Uncharacterized HIT-like protein ML2237;
           n=23; Actinomycetales|Rep: Uncharacterized HIT-like
           protein ML2237 - Mycobacterium leprae
          Length = 134

 Score = 56.4 bits (130), Expect = 2e-07
 Identities = 34/100 (34%), Positives = 51/100 (51%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           TIF KI+ +E+P +FVYEDD  VAF  + P    H LV+P   I Q       D  + G 
Sbjct: 3   TIFTKIINRELPGRFVYEDDDVVAFLTIEPMTQGHTLVVPCAEIDQWQNV---DPAIFGR 59

Query: 227 LLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHV 346
           ++ V++ +   +G+ ++ F             V HLH+HV
Sbjct: 60  VIAVSQLIG--KGVCRA-FNAERAGVIIAGFEVPHLHIHV 96


>UniRef50_A1G4L9 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein -
           Salinispora arenicola CNS205
          Length = 113

 Score = 55.6 bits (128), Expect = 3e-07
 Identities = 30/91 (32%), Positives = 46/91 (50%)
 Frame = +2

Query: 92  VYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLD 271
           V E +  +AF    P  P HI+V+P++ +  L   GD    LL  ++ V R+VA +   +
Sbjct: 20  VVETEDVLAFEHTRPFWPVHIVVVPKRHVPSLVDLGDASRDLLHRVIEVVRQVAARVERE 79

Query: 272 KSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           +   R++ N G+   Q   HLH HV  G  L
Sbjct: 80  QGACRVLTNLGR--YQDSKHLHFHVCSGAPL 108


>UniRef50_A7SFV5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 163

 Score = 55.6 bits (128), Expect = 3e-07
 Identities = 31/100 (31%), Positives = 49/100 (49%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F KI  KE   + +YED++ + F D+ P    H LVIP++          +D  L+  L
Sbjct: 12  VFCKISSKEQETRIIYEDEETLTFKDLRPATDHHYLVIPKQHYGNPKSLTGDDLPLVEKL 71

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           + V +KV  Q+  +      VI        S+ HLH+HV+
Sbjct: 72  MDVGKKVLVQQNANTED--TVIGFHWPPFNSIQHLHLHVI 109


>UniRef50_Q4LEG8 Cluster: Histidine triad protein; n=1; uncultured
           crenarchaeote 45-H-12|Rep: Histidine triad protein -
           uncultured crenarchaeote 45-H-12
          Length = 161

 Score = 55.6 bits (128), Expect = 3e-07
 Identities = 35/114 (30%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
 Frame = +2

Query: 14  ELAKSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSK 193
           + + S     + +F  I+  +  A  VYEDD  + F D  P +  H LVIP++  + +  
Sbjct: 4   DASSSVNKDDECVFCLIVEGKRDAAVVYEDDAMMVFMDKYPISNGHTLVIPKRHYTTIL- 62

Query: 194 AGDEDEQLLGHLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
             D + + +G L  +  KV  A    L+  GF +  N+GK   Q V H+HVH++
Sbjct: 63  --DMESRDVGMLFALVHKVAKAVVNALNAQGFSIAQNNGKVAHQVVPHVHVHIV 114


>UniRef50_Q9V017 Cluster: Histidine triad (HIT) protein; n=4;
           Thermococcaceae|Rep: Histidine triad (HIT) protein -
           Pyrococcus abyssi
          Length = 147

 Score = 54.8 bits (126), Expect = 5e-07
 Identities = 29/90 (32%), Positives = 48/90 (53%)
 Frame = +2

Query: 80  PAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQ 259
           P   VYED       D  P  P H+LV+P++ ++ +    ++++  L   + +A K A +
Sbjct: 10  PENVVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLKGIELAVK-ALK 68

Query: 260 EGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
             L   GF + IN GK   Q+V H+H+HV+
Sbjct: 69  RALKADGFNVGINIGKAAGQTVDHIHIHVI 98


>UniRef50_UPI0000D55AC3 Cluster: PREDICTED: similar to histidine
           triad protein 4; n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to histidine triad protein 4 -
           Tribolium castaneum
          Length = 138

 Score = 54.4 bits (125), Expect = 7e-07
 Identities = 27/100 (27%), Positives = 52/100 (52%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI+  + PA+  ++DD+ + F D+ P +  H L +P++ I  ++        L+  L
Sbjct: 5   IFCKIISGDAPAEIFHQDDKMIIFKDIKPASKHHFLAVPKEHIPNVNSLSKNQIPLINDL 64

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           +  +++V   +G +    RL  +       SV HLH+H++
Sbjct: 65  IAKSKQVLADKGGNLDDTRLGFH--LPPFNSVSHLHLHII 102


>UniRef50_Q03D63 Cluster: Diadenosine tetraphosphate (Ap4A)
           hydrolase related HIT family hydrolase; n=1; Pediococcus
           pentosaceus ATCC 25745|Rep: Diadenosine tetraphosphate
           (Ap4A) hydrolase related HIT family hydrolase -
           Pediococcus pentosaceus (strain ATCC 25745 / 183-1w)
          Length = 132

 Score = 54.4 bits (125), Expect = 7e-07
 Identities = 22/87 (25%), Positives = 45/87 (51%)
 Frame = +2

Query: 89  FVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGL 268
           ++ E+    +F D  P +  H L++P++ + QL +  +E+   +   L+   K    +  
Sbjct: 17  YIVENKLAASFLDFYPVSKGHTLIVPKRHVRQLWELNEEERHAI-FTLVEKNKAILDQKY 75

Query: 269 DKSGFRLVINDGKNGAQSVYHLHVHVL 349
              G+ +V+N G    QSV+H H+H++
Sbjct: 76  QPDGYNVVVNSGAAAGQSVFHCHIHLI 102


>UniRef50_Q7W2C9 Cluster: Histidine triad protein; n=4;
           Proteobacteria|Rep: Histidine triad protein - Bordetella
           parapertussis
          Length = 145

 Score = 54.0 bits (124), Expect = 9e-07
 Identities = 25/70 (35%), Positives = 43/70 (61%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F +I R+EIPA  +++D + +AF D++P  P H+L+IPR+         D    L G
Sbjct: 4   DCLFCRISREEIPAHVIHQDSRLLAFLDIHPVRPGHVLIIPRQHYPYFE---DMPADLAG 60

Query: 224 HLLIVARKVA 253
           H+L + +++A
Sbjct: 61  HILNLGQRLA 70


>UniRef50_A5KTI5 Cluster: Histidine triad (HIT) protein; n=1;
           candidate division TM7 genomosp. GTL1|Rep: Histidine
           triad (HIT) protein - candidate division TM7 genomosp.
           GTL1
          Length = 131

 Score = 54.0 bits (124), Expect = 9e-07
 Identities = 31/102 (30%), Positives = 55/102 (53%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           ++IF KI++ +IP+  +YEDD   AF D+ P  P H LV+ ++ + +  +  DE   L  
Sbjct: 3   ESIFTKIVKGDIPSYEIYEDDDIFAFLDIYPAQPGHTLVVTKQQLDRFEELPDE---LYQ 59

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            L+ V +K+A          R+ +   K     V+H+H+H++
Sbjct: 60  KLMAVVKKLAKHLHQMLKVERITM---KVEGFDVHHVHIHLI 98


>UniRef50_Q04344 Cluster: Hit family protein 1; n=22; Dikarya|Rep:
           Hit family protein 1 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 158

 Score = 54.0 bits (124), Expect = 9e-07
 Identities = 34/103 (33%), Positives = 55/103 (53%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF KI++ EIP+  + E     AF D+ P A  H L+IP+   ++L    DE    L   
Sbjct: 26  IFCKIIKSEIPSFKLIETKYSYAFLDIQPTAEGHALIIPKYHGAKLHDIPDE---FLTDA 82

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGR 358
           + +A+++A    LD   + ++ N+GK   Q V H+H H++  R
Sbjct: 83  MPIAKRLAKAMKLDT--YNVLQNNGKIAHQEVDHVHFHLIPKR 123


>UniRef50_UPI000155CE00 Cluster: PREDICTED: similar to aprataxin;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           aprataxin - Ornithorhynchus anatinus
          Length = 408

 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 31/90 (34%), Positives = 49/90 (54%)
 Frame = +2

Query: 80  PAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQ 259
           P   VY+D++ V   D  P+A  H LV+P + I+ L     E  +LL H+  V +K+ TQ
Sbjct: 190 PKMQVYKDEKVVVIKDKYPKARNHWLVLPWESIASLRAVTREHLELLKHMQAVGKKL-TQ 248

Query: 260 EGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           + +D    RL    G +   S+ H+H+HV+
Sbjct: 249 DCIDSD--RLQFRMGYHAIPSMSHIHLHVI 276


>UniRef50_Q1MR92 Cluster: 141aa long hypothetical histidine triad
           nucleotide-binding protein; n=1; Lawsonia
           intracellularis PHE/MN1-00|Rep: 141aa long hypothetical
           histidine triad nucleotide-binding protein - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 146

 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 6/115 (5%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF  I++K+IP   +Y  D  +A  D+NP    H L++P + +  +    D D  L  
Sbjct: 8   DCIFCNIIQKKIPCVSIYNSDNFIALLDINPVNKGHTLIVPTQHVETMF---DIDPSLGT 64

Query: 224 HLLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHV----LGGRQLEW 370
            LL + + +  A  +  +  G  ++ N+     Q V HLH H+    +G  ++ W
Sbjct: 65  DLLSIMQHIGPAIMKATNAEGVNVIQNNYVAAGQEVPHLHWHIIPRFIGDSRIRW 119


>UniRef50_Q64N76 Cluster: Histidine triad (HIT) family protein;
           n=14; cellular organisms|Rep: Histidine triad (HIT)
           family protein - Bacteroides fragilis
          Length = 134

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 31/101 (30%), Positives = 55/101 (54%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           TIF +I+  EIP   V E+++  AF D+NP    H LV+P++ +  +    DED   L  
Sbjct: 3   TIFSRIIAGEIPCYKVAENEKFFAFLDINPLVKGHTLVVPKQEVDYIFDLSDED---LAA 59

Query: 227 LLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           + + A+K+A    ++K+     + +   G + V H H+H++
Sbjct: 60  MHVFAKKIA--RAIEKAFPCKKVGEAVIGLE-VPHAHIHLI 97


>UniRef50_Q31N56 Cluster: Putative uncharacterized protein; n=2;
           Synechococcus elongatus|Rep: Putative uncharacterized
           protein - Synechococcus sp. (strain PCC 7942) (Anacystis
           nidulans R2)
          Length = 142

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 25/84 (29%), Positives = 45/84 (53%)
 Frame = +2

Query: 98  EDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKS 277
           E+D  VAF D  P +P H LV+P++ +  L +    + Q    L+ + R +  Q+    +
Sbjct: 19  ENDWAVAFRDRYPVSPGHSLVVPKRAVGSLFELPTAEFQASWELVAIVRSLLQQQ-YQPA 77

Query: 278 GFRLVINDGKNGAQSVYHLHVHVL 349
           GF + +NDG    Q++   H+H++
Sbjct: 78  GFNVGLNDGLAAGQTIDQAHIHLI 101


>UniRef50_Q01IH1 Cluster: OSIGBa0159I10.14 protein; n=6;
           Magnoliophyta|Rep: OSIGBa0159I10.14 protein - Oryza
           sativa (Rice)
          Length = 141

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 35/104 (33%), Positives = 54/104 (51%), Gaps = 4/104 (3%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFV--YEDDQCVAFHDVNPQAPTHILVIPRKPISQLS--KAGDEDEQL 217
           +F  I R++     V  Y DD+ +AF D+NP A  H LVIP + I  ++  +   ED QL
Sbjct: 6   VFCPIARRDPACNTVLLYSDDRVMAFKDINPSAFRHYLVIPIEHIPTVNNLQRTTEDHQL 65

Query: 218 LGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           + H+L V R +  ++  +    R   +  +    SV HLH+H L
Sbjct: 66  VSHMLAVGRDLLNRDAPNSEEQRFGFH--QPPFNSVDHLHLHCL 107


>UniRef50_Q6L1V3 Cluster: Asymmetrical
           bis(5'-nucleosyl)-tetraphosphatase; n=2;
           Thermoplasmatales|Rep: Asymmetrical
           bis(5'-nucleosyl)-tetraphosphatase - Picrophilus
           torridus
          Length = 141

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 33/100 (33%), Positives = 48/100 (48%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F + + K+  A FVYEDD  VAF D  P    HILVIPR+    +    D D  +  + 
Sbjct: 7   VFCREIIKKRNAAFVYEDDDVVAFMDNAPIDNGHILVIPREHYQDIFSI-DNDLYIKIYK 65

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            +          L+  G  +  N+G+   Q V H HVH++
Sbjct: 66  TVKKLAPVLISSLNAQGLNISQNNGRAANQVVMHYHVHMI 105


>UniRef50_A4YEP9 Cluster: Histidine triad (HIT) protein; n=1;
           Metallosphaera sedula DSM 5348|Rep: Histidine triad
           (HIT) protein - Metallosphaera sedula DSM 5348
          Length = 145

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 2/89 (2%)
 Frame = +2

Query: 89  FVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLL--IVARKVATQE 262
           FVY D++  A  D  P AP H LV+P +  + L      D  LL  ++   V    A +E
Sbjct: 16  FVYRDNEISAILDKYPSAPGHTLVMPNRHYNDLLVT---DPALLTPIVQKTVLIAKAIKE 72

Query: 263 GLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            L+ SG R++ N G++  Q ++H H+H++
Sbjct: 73  VLNASGVRILTNIGRSAGQVIFHTHIHII 101


>UniRef50_Q67LQ3 Cluster: HIT family protein; n=1; Symbiobacterium
           thermophilum|Rep: HIT family protein - Symbiobacterium
           thermophilum
          Length = 339

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 3/122 (2%)
 Frame = +2

Query: 2   GGEVELAKSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPIS 181
           GG VE A+      + +F +I      A  VYED   +AF ++    P H+LVIP++ + 
Sbjct: 188 GGLVERARRTR--AECLFCRIATGG-EASRVYEDPYTLAFMNIRQANPGHVLVIPKRHVE 244

Query: 182 QL-SKAGDEDEQLLGHL--LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLG 352
           Q+     D D  L G L   I A   A +     +   +  N+G+   Q +YH+H H+  
Sbjct: 245 QVFDLDSDLDSDLAGRLGQTIAAVSRAIRAAFGVTDLNVFQNNGEAAGQEIYHVHFHLFP 304

Query: 353 GR 358
            R
Sbjct: 305 RR 306


>UniRef50_A0RX45 Cluster: Asymmetrical
           bis(5'-nucleosyl)-tetraphosphatase; n=2;
           Thermoprotei|Rep: Asymmetrical
           bis(5'-nucleosyl)-tetraphosphatase - Cenarchaeum
           symbiosum
          Length = 141

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 36/112 (32%), Positives = 52/112 (46%), Gaps = 5/112 (4%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF +I+R      FVY D   +A  D  P    H LVIPR+    +   G+ D + +G L
Sbjct: 5   IFCEIIRGGRRGAFVYRDGGAIAILDKYPIDLGHCLVIPREHHETI---GEMDPRAVGDL 61

Query: 230 LIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL---GGRQLEW 370
                K+  A   G     F +  N+G+   Q V H+H+H++    GR  EW
Sbjct: 62  FSRVPKIARAVVAGTGADAFSIAQNNGRAARQIVPHVHIHIIPRFNGRTTEW 113


>UniRef50_A0RUN5 Cluster: Diadenosine tetraphosphate hydrolase; n=4;
           Crenarchaeota|Rep: Diadenosine tetraphosphate hydrolase
           - Cenarchaeum symbiosum
          Length = 138

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 31/102 (30%), Positives = 52/102 (50%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F KI   E+PA+ + E    +AF D  P A  H LVIP+    ++ +  + +   L 
Sbjct: 5   DCVFCKIASGELPARIISETGNTIAFMDAFPVARGHSLVIPKGHYERMQEIPESENADL- 63

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
              +V R VA  + +  S   + +++G+   Q V H HVH++
Sbjct: 64  -FEVVRRVVARVDEMGGSTL-VALHNGRGSGQEVPHAHVHLI 103


>UniRef50_Q7Z2E3 Cluster: Aprataxin; n=44; Euteleostomi|Rep:
           Aprataxin - Homo sapiens (Human)
          Length = 356

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
 Frame = +2

Query: 80  PAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQ 259
           P   VY+D+Q V   D  P+A  H LV+P   IS L     E  +LL H+  V  KV   
Sbjct: 192 PKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVD 251

Query: 260 -EGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
             G  K  FRL    G +   S+ H+H+HV+
Sbjct: 252 FAGSSKLRFRL----GYHAIPSMSHVHLHVI 278


>UniRef50_Q65J74 Cluster: Putative uncharacterized protein; n=1;
           Bacillus licheniformis ATCC 14580|Rep: Putative
           uncharacterized protein - Bacillus licheniformis (strain
           DSM 13 / ATCC 14580)
          Length = 142

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDE--DEQLLG 223
           IF +I+ ++I +  VY+ D   AF D+NP    H L+IP K I +L    D     +++ 
Sbjct: 9   IFCEIVSRKISSFEVYKTDYVTAFLDINPVTNGHTLIIPNKHIERLDHINDPHLSNEIMD 68

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            L+ V  ++  Q G+    + ++ ++G    Q + HLH HV+
Sbjct: 69  SLIKVP-QLLIQSGI-CDDYTILSDNGHFAQQDIKHLHFHVI 108


>UniRef50_Q84VV6 Cluster: At4g16566; n=2; Arabidopsis thaliana|Rep:
           At4g16566 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 146

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 32/100 (32%), Positives = 56/100 (56%), Gaps = 2/100 (2%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLS--KAGDEDEQLLG 223
           IF +I+R     + ++ D++ +AF D+ P A  H LVIP++ I  ++  +  DED  L+ 
Sbjct: 9   IFCEIVRNPTTTRLLHTDEKVIAFQDIKPAAQRHYLVIPKEHIPTVNDLQRRDEDYSLVR 68

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVH 343
           H+L V +++  Q+   +S  R   +  +    SV HLH+H
Sbjct: 69  HMLSVGQQL-LQKDAPQSIHRFGFH--QPPFNSVDHLHLH 105


>UniRef50_Q702F5 Cluster: Putative HIT superfamily hydrolase; n=1;
           uncultured crenarchaeote|Rep: Putative HIT superfamily
           hydrolase - uncultured crenarchaeote
          Length = 146

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 33/101 (32%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAG-DEDEQLLGH 226
           IF  I +    A+ + E++  VAF D  P    H LV  +    +L +   DE   L G 
Sbjct: 11  IFCNIAKYITKARIISENEHAVAFLDAFPLRRGHTLVATKMHWVKLQEINSDEIVALFGL 70

Query: 227 LLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           + +VA   A ++G+D +   + I++GK   Q + HLHVH+L
Sbjct: 71  VSLVAD--ALEKGMDANATLIAIHNGKQAGQEIPHLHVHIL 109


>UniRef50_Q9PQL9 Cluster: Probable HIT protein; n=1; Ureaplasma
           parvum|Rep: Probable HIT protein - Ureaplasma parvum
           (Ureaplasma urealyticum biotype 1)
          Length = 152

 Score = 51.6 bits (118), Expect = 5e-06
 Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 3/105 (2%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF KIL+ EI +K + E++  +A  D+ P +  H+L+IP+K     S     D   L 
Sbjct: 3   DCIFCKILKGEIISKIIDENEFAIAILDIQPASDGHMLIIPKKHYRNFSLT---DPIYLD 59

Query: 224 HLLIVARK---VATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            ++ +A+    V  +   +  GF  ++N   +  Q + H H+H++
Sbjct: 60  GMMRLAKNMTFVLEEVFPNVLGFNYLMNSNSSAGQVIMHTHLHII 104


>UniRef50_Q2BQP2 Cluster: HIT domain protein; n=1; Neptuniibacter
           caesariensis|Rep: HIT domain protein - Neptuniibacter
           caesariensis
          Length = 84

 Score = 51.6 bits (118), Expect = 5e-06
 Identities = 27/67 (40%), Positives = 41/67 (61%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F  I R E  A+ VY+D+  VAF D  P+AP H+LVIP + I  L+   +    L+ HL
Sbjct: 1   MFCCIARGEEAAECVYQDEYRVAFKDRAPKAPVHLLVIPCQHIRNLNDLREAGAALVAHL 60

Query: 230 LIVARKV 250
           ++ +RK+
Sbjct: 61  VLKSRKL 67


>UniRef50_Q5VQQ9 Cluster: Putative uncharacterized protein
           P0425G02.35; n=1; Oryza sativa (japonica
           cultivar-group)|Rep: Putative uncharacterized protein
           P0425G02.35 - Oryza sativa subsp. japonica (Rice)
          Length = 143

 Score = 51.6 bits (118), Expect = 5e-06
 Identities = 24/53 (45%), Positives = 35/53 (66%)
 Frame = +2

Query: 161 IPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQ 319
           IP + + +  KA +   +++GHLL  A+ +A QE LD  GFR+VINDG NG +
Sbjct: 80  IPSQVVYEDEKAEERHVEVMGHLLYAAKTIAKQENLD-DGFRIVINDGPNGCE 131



 Score = 45.2 bits (102), Expect = 4e-04
 Identities = 23/41 (56%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
 Frame = +2

Query: 5   GEVELAKSAAPG-GDTIFGKILRKEIPAKFVYEDDQCVAFH 124
           GE E A +A P  G TIF KILRKEIP++ VYED++    H
Sbjct: 55  GEKEAALAAGPSDGPTIFDKILRKEIPSQVVYEDEKAEERH 95


>UniRef50_A4AKY1 Cluster: Putative uncharacterized protein; n=1;
           marine actinobacterium PHSC20C1|Rep: Putative
           uncharacterized protein - marine actinobacterium
           PHSC20C1
          Length = 153

 Score = 51.2 bits (117), Expect = 6e-06
 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 1/101 (0%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           +IF +IL    P +F++ DD+  A   + P+ P H+LVIPR  I + S+    DE+L  H
Sbjct: 3   SIFTEILNGRSPGRFIWADDRLFAILTIEPRKPGHVLVIPRVEIDRWSEL---DEELAMH 59

Query: 227 LLIVARKVATQEGLDKSGFRL-VINDGKNGAQSVYHLHVHV 346
           +  V R +   +  + +  R+ ++ +G      V H H+HV
Sbjct: 60  IFRVGRLIGLAQREEWNADRVGLMFEG----YRVPHAHLHV 96


>UniRef50_A1SG63 Cluster: Histidine triad (HIT) protein; n=3;
           Actinomycetales|Rep: Histidine triad (HIT) protein -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 142

 Score = 50.8 bits (116), Expect = 8e-06
 Identities = 34/102 (33%), Positives = 55/102 (53%), Gaps = 2/102 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           +F  I+  E+PA  V E+ + + F D  P    H L++PR+ +  L    D   +L    
Sbjct: 6   VFCGIVAGEVPADLVLEETEVLGFLDRRPLFKGHTLLVPREHVVTLP---DLPARLRDPY 62

Query: 230 LIVARKVAT--QEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           L  A+++AT  ++GL   G  + +N+    +QSV HLHVHV+
Sbjct: 63  LAAAQRLATAMRDGLGAQGSFVAVNNVV--SQSVAHLHVHVV 102


>UniRef50_A1AWF6 Cluster: Histidine triad (HIT) protein; n=1;
           Candidatus Ruthia magnifica str. Cm (Calyptogena
           magnifica)|Rep: Histidine triad (HIT) protein - Ruthia
           magnifica subsp. Calyptogena magnifica
          Length = 130

 Score = 50.8 bits (116), Expect = 8e-06
 Identities = 22/88 (25%), Positives = 46/88 (52%)
 Frame = +2

Query: 86  KFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEG 265
           + + + D  + F D  P +P H L++P++ ++      ++++  +    I   K+   E 
Sbjct: 14  RIIGQCDLTITFLDSYPVSPGHTLIVPKRHVATYFDITEQEQNAIAKA-IQKSKLILDEE 72

Query: 266 LDKSGFRLVINDGKNGAQSVYHLHVHVL 349
               GF + +N+G+   QS+ HLHVH++
Sbjct: 73  FSPDGFNIGMNNGEVAGQSIMHLHVHMI 100


>UniRef50_A0LI77 Cluster: Type III restriction enzyme, res subunit;
           n=2; Deltaproteobacteria|Rep: Type III restriction
           enzyme, res subunit - Syntrophobacter fumaroxidans
           (strain DSM 10017 / MPOB)
          Length = 1077

 Score = 50.8 bits (116), Expect = 8e-06
 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
 Frame = +2

Query: 95  YEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDED-EQLLGHLLIVARKVATQEGLD 271
           YE     A  D  P AP H L++P++ ++    A  E+ E+LL    +V   + +    +
Sbjct: 18  YEGKLVFALWDGFPVAPGHALLVPKRHVATWFDATPEEREELLAATEVVRDHILSH--FE 75

Query: 272 KSGFRLVINDGKNGAQSVYHLHVHVL 349
            +GF L IN G    Q+V+HLH+HV+
Sbjct: 76  PAGFNLGINIGTAAGQTVFHLHLHVI 101


>UniRef50_P61799 Cluster: Aprataxin; n=21; Deuterostomia|Rep:
           Aprataxin - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 324

 Score = 50.8 bits (116), Expect = 8e-06
 Identities = 33/91 (36%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
 Frame = +2

Query: 80  PAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQ 259
           P   VY+DD  V   D  P+A  H LV+P + IS L     E  +LL H+  VA ++  Q
Sbjct: 160 PKMQVYKDDSVVVIKDKYPKARYHWLVLPWQSISSLKALRSEHVELLKHMQRVADQMVEQ 219

Query: 260 -EGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
                K  FRL    G +   S+ H+H+HV+
Sbjct: 220 CPDAHKLSFRL----GYHAIPSMSHVHLHVI 246


>UniRef50_UPI0000DB7407 Cluster: PREDICTED: similar to histidine
           triad protein 4; n=2; Apis mellifera|Rep: PREDICTED:
           similar to histidine triad protein 4 - Apis mellifera
          Length = 140

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 26/100 (26%), Positives = 52/100 (52%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF  I+  + P++ +YED+      D++P +  H L++P++ I    +   E  +L   +
Sbjct: 8   IFCDIINNKEPSEKIYEDNYVTCIKDIHPVSTHHYLILPKEHIRNAKQLKPEHSELYDKM 67

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           L     ++ ++GLD++  R   +       +V HLH+HV+
Sbjct: 68  LAAIDIISQKQGLDRAVTRTGFH--WPPFNTVSHLHLHVI 105


>UniRef50_Q4RFE2 Cluster: Chromosome 8 SCAF15119, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 8
           SCAF15119, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 166

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
 Frame = +2

Query: 14  ELAKSAAPGGDT--IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQL 187
           +L   +A G D   IF KI+ KE+  + ++ D +   F D+ P AP H LV+P K +   
Sbjct: 16  KLGNVSAEGYDKKCIFCKIVNKELETELLHCDGEISCFRDIRPGAPHHYLVVPTKHVGNC 75

Query: 188 SKAGDEDEQLLGHLLIVARKVATQEGL-DKSGFRLVINDGKNGAQSVYHLHVHVL 349
                E   L+  ++ + +++  +  + D S  R   +       SV HLH+HVL
Sbjct: 76  KSLSKEHVPLVQRMVELGKEILQKNDVTDLSDARFGFH--WPPFCSVTHLHLHVL 128


>UniRef50_Q8FTW3 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium efficiens|Rep: Putative uncharacterized
           protein - Corynebacterium efficiens
          Length = 333

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 23/86 (26%), Positives = 43/86 (50%)
 Frame = +2

Query: 92  VYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLD 271
           VY +D  VAFH   P    H LV+P + +  +     E+   L   +++    A +  + 
Sbjct: 33  VYRNDHVVAFHPTEPATLGHTLVVPHRHVENVWDLAAEEANHLSQAVLLLSD-AVRAAVH 91

Query: 272 KSGFRLVINDGKNGAQSVYHLHVHVL 349
             G  ++ ++G+   Q++ HLHVH++
Sbjct: 92  PEGLNIIQSNGEAATQTIPHLHVHLV 117


>UniRef50_A4BW57 Cluster: HIT family protein; n=14;
           Bacteroidetes|Rep: HIT family protein - Polaribacter
           irgensii 23-P
          Length = 131

 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQL-SKAGDEDEQLLG 223
           +IF KI+  E+P+  V E+D  +AF D+NP A  H LV+P+   +++   + D   QLL 
Sbjct: 2   SIFTKIITGEVPSYKVAENDNFIAFLDINPNAKGHALVVPKVEENKIFGLSRDAYHQLLD 61

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
               VA+ +       + G  ++          V H+HVH++
Sbjct: 62  FSYTVAKSLEKAISCKRVGMSII-------GLEVPHVHVHLI 96


>UniRef50_Q01D01 Cluster: Diadenosine tetraphosphate hydrolase; n=1;
           Ostreococcus tauri|Rep: Diadenosine tetraphosphate
           hydrolase - Ostreococcus tauri
          Length = 154

 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 36/115 (31%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
 Frame = +2

Query: 20  AKSAAPGGDTIFGKILRKEIPAKFVY-EDDQCVAFHDVNPQAPTHILVIPRKPISQLSKA 196
           A S++  G T FG I   +IP+  ++ E     A  ++ P  P H+LV PR+   + +  
Sbjct: 3   ASSSSHPGAT-FGPI---DIPSTQIFHETPTTFALVNLKPVVPGHVLVCPRRVARKFTDL 58

Query: 197 GDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQ 361
            D++   L   +   ++V  +   D +   L I DG    QSV H+HVHVL  R+
Sbjct: 59  SDDEIGDLWRTVAAVQRVM-ERVYDTTSSTLAIQDGPLAGQSVPHVHVHVLPRRE 112


>UniRef50_O76463 Cluster: Nitrilase and fragile histidine triad
           fusion protein NitFhit [Includes:
           Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29)
           (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase)
           (Dinucleosidetriphosphatase) (AP3A hydrolase) (AP3Aase);
           Nitrilase homolog (EC 3.5.-.-)]; n=4; Bilateria|Rep:
           Nitrilase and fragile histidine triad fusion protein
           NitFhit [Includes: Bis(5'-adenosyl)-triphosphatase (EC
           3.6.1.29) (Diadenosine 5',5'''-P1,P3-triphosphate
           hydrolase) (Dinucleosidetriphosphatase) (AP3A hydrolase)
           (AP3Aase); Nitrilase homolog (EC 3.5.-.-)] -
           Caenorhabditis elegans
          Length = 440

 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 30/103 (29%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
 Frame = +2

Query: 59  KILRKEIPAKFV-YEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLI 235
           K  R  IPA  + Y       F ++ P    H+LV P++ + +L+   D +      L I
Sbjct: 300 KFARFNIPADHIFYSTPHSFVFVNLKPVTDGHVLVSPKRVVPRLTDLTDAET---ADLFI 356

Query: 236 VARKVAT--QEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGR 358
           VA+KV    ++  + +   + + DGK+  Q+V H+H+H+L  R
Sbjct: 357 VAKKVQAMLEKHHNVTSTTICVQDGKDAGQTVPHVHIHILPRR 399


>UniRef50_Q5WBH5 Cluster: Histidine triad protein involved in
           cell-cycle regulation; n=1; Bacillus clausii
           KSM-K16|Rep: Histidine triad protein involved in
           cell-cycle regulation - Bacillus clausii (strain
           KSM-K16)
          Length = 134

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDED 208
           +F  I  KE+ +  VYED+Q +AF D+ P  P H+LVIP++    L   G+++
Sbjct: 4   LFCAIANKEVKSHIVYEDEQAIAFLDIQPINPGHMLVIPKRHQEALHTLGEQE 56


>UniRef50_A1VWA8 Cluster: Histidine triad (HIT) protein; n=5;
           cellular organisms|Rep: Histidine triad (HIT) protein -
           Polaromonas naphthalenivorans (strain CJ2)
          Length = 133

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
 Frame = +2

Query: 77  IPA-KFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVA 253
           +PA + V E+   V   D  P +P H LVIP++ +    +    + + L  LL  A+++ 
Sbjct: 15  LPASRIVEENAHAVLILDGYPVSPGHSLVIPKRHVRSFFEVTAPEREALFALLDRAKELV 74

Query: 254 TQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            ++     G+ + INDG    Q+V HLH+H++
Sbjct: 75  AEQHRP-DGYNIGINDGAAAGQTVPHLHIHLI 105


>UniRef50_Q55V28 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 127

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
 Frame = +2

Query: 98  EDDQCVAFHDVNPQAPTHILVIPRKPI-SQLSKAGDEDEQLLGHLLIVARKVATQEGLDK 274
           +D + +AFHD  P+A TH+L+IPR  + S + +   E   LL  +  ++R +   +   K
Sbjct: 2   QDQELIAFHDRTPRAVTHLLIIPRSHVASSVRQLTHEHLPLLDSMAALSRTLVPSKPTPK 61

Query: 275 SGFRLVINDGKNGAQSVYHLHVHVLGG 355
            GF +          SV H+H+HV  G
Sbjct: 62  LGFHI------PPFSSVPHIHLHVFSG 82


>UniRef50_UPI00003C03A1 Cluster: PREDICTED: similar to aprataxin;
           n=1; Apis mellifera|Rep: PREDICTED: similar to aprataxin
           - Apis mellifera
          Length = 194

 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 32/98 (32%), Positives = 51/98 (52%)
 Frame = +2

Query: 56  GKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLI 235
           G ++  E P   V EDD+ +   D  P+A  H L+IP+  I  L     E+E LL H+  
Sbjct: 23  GLLVSMEDPRYKVKEDDKIIVIKDKYPKAQNHYLIIPKIDIPSLWHVKKENEDLLLHMHA 82

Query: 236 VARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           +A  + T+E  +   F  +I  G +   S++ LH+HV+
Sbjct: 83  IAEDL-TKEHKE---FEFLI--GYHAVPSMHRLHLHVI 114


>UniRef50_A0W3X6 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein - Geobacter
           lovleyi SZ
          Length = 114

 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 30/102 (29%), Positives = 49/102 (48%)
 Frame = +2

Query: 59  KILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIV 238
           KIL+  +      ++D+  AF+  NP    H++++P++ I  L    + D +LL  L+  
Sbjct: 12  KILKGLLEVPVYLQNDRVFAFYHTNPLWEHHVVLLPKRHIESLISLEESDNELLLELMRT 71

Query: 239 ARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQL 364
           A+ +A          R+  N G    QS  HLH H+  G QL
Sbjct: 72  AKLIAADFMARFGACRVYTNLGT--YQSSKHLHWHIGAGEQL 111


>UniRef50_UPI00015B4880 Cluster: PREDICTED: similar to FHA-HIT; n=1;
           Nasonia vitripennis|Rep: PREDICTED: similar to FHA-HIT -
           Nasonia vitripennis
          Length = 205

 Score = 48.8 bits (111), Expect = 3e-05
 Identities = 33/103 (32%), Positives = 50/103 (48%)
 Frame = +2

Query: 41  GDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLL 220
           G    G +     P   V EDD+     D  P+A  H LV+P+K IS +S+   +D +LL
Sbjct: 29  GHWSLGLLTSMNDPESKVEEDDRIAVIKDKYPKARFHYLVLPKKDISTISEVTRDDIELL 88

Query: 221 GHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            H+  +A K      + K    LV   G +   S++ LH+HV+
Sbjct: 89  QHMENIANKFV---DIHKDYEFLV---GYHAIPSMHRLHLHVI 125


>UniRef50_UPI000038E073 Cluster: hypothetical protein Faci_03000287;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03000287 - Ferroplasma acidarmanus fer1
          Length = 137

 Score = 48.8 bits (111), Expect = 3e-05
 Identities = 26/106 (24%), Positives = 59/106 (55%), Gaps = 2/106 (1%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF  I+  ++ +  +YE ++ +AF D++P +  HILVIP++    +    + D  +L   
Sbjct: 3   IFCDIVNDKVKSHKIYETNKTLAFLDIHPISNGHILVIPKEHYKDIY---EMDSNILIET 59

Query: 230 LIVARKVA--TQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQ 361
           +   + +    ++ L+ +   ++ ++G+   Q+V+H H+HV+  R+
Sbjct: 60  IKTVKAITGILKDKLNINAVNIMNSNGEIANQTVFHYHIHVIPRRE 105


>UniRef50_Q02WI9 Cluster: Diadenosine tetraphosphate (Ap4A)
           hydrolase related HIT family hydrolase; n=5;
           Firmicutes|Rep: Diadenosine tetraphosphate (Ap4A)
           hydrolase related HIT family hydrolase - Lactococcus
           lactis subsp. cremoris (strain SK11)
          Length = 122

 Score = 48.8 bits (111), Expect = 3e-05
 Identities = 23/86 (26%), Positives = 46/86 (53%)
 Frame = +2

Query: 92  VYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLD 271
           V+E++   AF+D  P +  HIL+ P++ ++   +    + + +  LL ++ K    E   
Sbjct: 13  VFENELAQAFYDAYPVSEGHILITPKRHVASYFELTKYEREAIEELLELS-KSHLDENFH 71

Query: 272 KSGFRLVINDGKNGAQSVYHLHVHVL 349
            + + + IN G    Q+V+H HVH++
Sbjct: 72  ANAYNIGINVGHAAGQTVFHCHVHLI 97


>UniRef50_A7BYS1 Cluster: HIT family protein; n=2;
           Proteobacteria|Rep: HIT family protein - Beggiatoa sp.
           PS
          Length = 125

 Score = 48.8 bits (111), Expect = 3e-05
 Identities = 23/88 (26%), Positives = 47/88 (53%)
 Frame = +2

Query: 86  KFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEG 265
           + +++D+      D  P +  H L+IP++ I+ L  A +++++ L + L    K    + 
Sbjct: 14  QIIFQDEFVFTIRDGFPISSAHTLIIPKRHIASLFDATNKEQRALLNALQFT-KTELDQI 72

Query: 266 LDKSGFRLVINDGKNGAQSVYHLHVHVL 349
               G+ + +NDG    Q+V HLH+H++
Sbjct: 73  YKPDGYNIGLNDGLAAGQTVMHLHIHLI 100


>UniRef50_Q4RR26 Cluster: Chromosome 14 SCAF15003, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14
           SCAF15003, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 277

 Score = 48.4 bits (110), Expect = 4e-05
 Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 6/117 (5%)
 Frame = +2

Query: 17  LAKSAAPGGDTI-FGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSK 193
           +A   A G D   F +I  K+   + ++ D++ + F DV P A TH LV+ R+ I     
Sbjct: 144 MATQEASGDDVCPFCQIADKQTNTEILFSDEELLCFRDVKPGAETHFLVVTRRHIDNCRM 203

Query: 194 AGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQ-----SVYHLHVHVL 349
              +   L+  ++ VAR V  +  +  S       D + G       SV HLH+HVL
Sbjct: 204 LQTQHIPLVERMVEVARSVLEENKVHNS------EDNRMGFHLPPFTSVPHLHLHVL 254



 Score = 43.6 bits (98), Expect = 0.001
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
 Frame = +2

Query: 98  EDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGL-DK 274
           +D   V F D+ P AP H LV+P   I           +L+  +  + R V   +G+ D 
Sbjct: 1   QDKDLVCFKDIYPAAPHHYLVVPVPHIISCHSLQRRHVKLVERMAEMGRAVLRDQGITDL 60

Query: 275 SGFRLVINDGKNGAQSVYHLHVHVL 349
           S  RL  +  +    SV+HLH+HVL
Sbjct: 61  SDIRLGFH--QPPFTSVHHLHLHVL 83


>UniRef50_Q6NFF8 Cluster: HIT family protein; n=4;
           Corynebacterium|Rep: HIT family protein -
           Corynebacterium diphtheriae
          Length = 141

 Score = 48.4 bits (110), Expect = 4e-05
 Identities = 33/102 (32%), Positives = 49/102 (48%), Gaps = 2/102 (1%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           ++F KI+  ++P +FVY D   VAF  + P A  H+LV+   P+ ++ K  D + +L   
Sbjct: 3   SVFTKIINGDLPGRFVYRDAHIVAFLTIEPLAYGHVLVV---PVKEVDKWTDLEPELWTE 59

Query: 227 LLIVARKV--ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHV 346
           L  VA KV  A     D      +I         V H H+HV
Sbjct: 60  LNAVALKVGQAVVSAFDAPRAGYII-----AGFDVPHTHIHV 96


>UniRef50_UPI000050FB45 Cluster: COG0537: Diadenosine tetraphosphate
           (Ap4A) hydrolase and other HIT family hydrolases; n=1;
           Brevibacterium linens BL2|Rep: COG0537: Diadenosine
           tetraphosphate (Ap4A) hydrolase and other HIT family
           hydrolases - Brevibacterium linens BL2
          Length = 144

 Score = 48.0 bits (109), Expect = 6e-05
 Identities = 27/104 (25%), Positives = 53/104 (50%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F  I+  ++P   V E +   AF D+ P +  H+LV+P++  + L      D   L 
Sbjct: 4   DCLFCGIVAGDVPGAKVAETETTYAFMDIQPGSDGHLLVVPKRHSTDLRDIPSAD---LA 60

Query: 224 HLLIVARKVATQ--EGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            + I ++++A    +     G  L+   G++  Q+V+H H+H++
Sbjct: 61  EVAIESQRIAKHVFDAWGADGVNLLNCCGEDAWQTVFHFHMHLI 104


>UniRef50_A0YDE8 Cluster: Probable HIT family protein; n=1; marine
           gamma proteobacterium HTCC2143|Rep: Probable HIT family
           protein - marine gamma proteobacterium HTCC2143
          Length = 172

 Score = 47.6 bits (108), Expect = 8e-05
 Identities = 28/102 (27%), Positives = 50/102 (49%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D IF +I++   P   V+EDD  + F D+ P    H+L++ ++  S L +A       +G
Sbjct: 38  DCIFCQIVQGNAPCHKVHEDDLTITFLDIFPATAGHLLIVTKEHFSDLLEATPAAIAQVG 97

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
               VA   A Q+ +   G  +   +     Q+V+H H+H++
Sbjct: 98  -ANSVAVAAAIQQVIAPDGLGIYQLNKPAAGQTVFHYHMHLI 138


>UniRef50_Q5DHH9 Cluster: SJCHGC02494 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC02494 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 202

 Score = 47.6 bits (108), Expect = 8e-05
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
 Frame = +2

Query: 95  YEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQ--EGL 268
           Y+     AF +++P  P H+LV P   + +           +  L +  R+VA +  E  
Sbjct: 60  YQSQLSFAFVNISPLVPGHVLVCPIVCVQRFCHLNPAQ---IADLYMTVRQVAKRLAEYF 116

Query: 269 DKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWP 373
             +   + I DGK+  QSV H+HVH+L  +  ++P
Sbjct: 117 SATSLTISIQDGKDAGQSVAHVHVHILPRKPNDFP 151


>UniRef50_UPI0000D55BA8 Cluster: PREDICTED: similar to aprataxin;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           aprataxin - Tribolium castaneum
          Length = 199

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 29/109 (26%), Positives = 51/109 (46%)
 Frame = +2

Query: 23  KSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGD 202
           K   P G    G +   + P  F+  DD      D  P+A  H LV+P++ I+ +     
Sbjct: 15  KKNKPNGHWSMGLLAAIDDPKLFIESDDLIHIIRDKYPKAKFHYLVLPKEDITSIKSVTS 74

Query: 203 EDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
               LL H+  VA ++ +++   +S F++    G +   S+  LH+HV+
Sbjct: 75  THLSLLKHMEQVALELISRDKHKESTFKI----GYHAEPSMSRLHLHVI 119


>UniRef50_P61802 Cluster: Aprataxin; n=1; Ciona intestinalis|Rep:
           Aprataxin - Ciona intestinalis (Transparent sea squirt)
          Length = 380

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 29/92 (31%), Positives = 47/92 (51%)
 Frame = +2

Query: 74  EIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVA 253
           E P   V ED+Q V   D  P+A  H L++P+  IS       ++ +LL H+L V +++A
Sbjct: 214 EDPELVVKEDEQIVVIKDKYPKAKYHWLILPKDSISSTKNLSTDNIELLKHILKVGQELA 273

Query: 254 TQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
             E  DK    +    G +   S+  +H+HV+
Sbjct: 274 A-EVKDKQP-DVEFRFGYHAVASMSQMHMHVI 303


>UniRef50_UPI0000D55F17 Cluster: PREDICTED: similar to CG7067-PA;
           n=2; Coelomata|Rep: PREDICTED: similar to CG7067-PA -
           Tribolium castaneum
          Length = 445

 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
 Frame = +2

Query: 71  KEIPAKFV-YEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARK 247
           K IPA  V Y    C AF ++    P H+L+   +   +L     E+   L  L  V  +
Sbjct: 305 KIIPASTVFYRTRHCYAFTNIRCVVPGHVLISTVRCCKRLEDLTSEEVTDL-FLTAVKVQ 363

Query: 248 VATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            A +     S   L + DGK+  Q++ H+H+H+L
Sbjct: 364 KAVENEYSASSSTLCVQDGKHAGQTIPHVHIHIL 397


>UniRef50_Q9HIK0 Cluster: Cell-cycle regulation histidine triad
           (HIT) related protein; n=2; Thermoplasma|Rep: Cell-cycle
           regulation histidine triad (HIT) related protein -
           Thermoplasma acidophilum
          Length = 160

 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
 Frame = +2

Query: 53  FGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDED-EQLLGHL 229
           F  I+  +  ++ VY D+  VAF D  P    H L++PRK  + +    D    +++  +
Sbjct: 22  FCDIISGKTASEIVYSDENFVAFLDYKPLFKGHTLLVPRKHFADIYAMDDLTLSKMMKTV 81

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            I++  V    G D  G  + IN+    +QSV H+HVH++
Sbjct: 82  TIISMAVERATGSD--GTFIAINN--KVSQSVPHVHVHIV 117


>UniRef50_Q4JA00 Cluster: HIT family protein; n=1; Sulfolobus
           acidocaldarius|Rep: HIT family protein - Sulfolobus
           acidocaldarius
          Length = 141

 Score = 46.0 bits (104), Expect = 2e-04
 Identities = 24/86 (27%), Positives = 40/86 (46%)
 Frame = +2

Query: 92  VYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLD 271
           VY D+   AF D  P AP H L++       +    +     LG  + +    + +  + 
Sbjct: 10  VYRDNYYTAFLDKYPIAPGHTLLVTNAHFENILDTSETHLNDLGKTIKMLAN-SIKRAVK 68

Query: 272 KSGFRLVINDGKNGAQSVYHLHVHVL 349
             G R+V N G++  Q V+H HVH++
Sbjct: 69  ADGIRVVSNAGRSAMQIVFHFHVHII 94


>UniRef50_Q28BZ2 Cluster: Histidine triad nucleotide binding protein
           3; n=2; Tetrapoda|Rep: Histidine triad nucleotide
           binding protein 3 - Xenopus tropicalis (Western clawed
           frog) (Silurana tropicalis)
          Length = 153

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
 Frame = +2

Query: 50  IFGKILRK-EIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           IF +I  K E  A+ ++ DD  V F D+ P    H LV+P+K +        +  QL+  
Sbjct: 20  IFCRIANKQESGAELLHSDDDLVCFKDIRPAVTHHYLVVPKKHVGTCKTLTKDHVQLIKT 79

Query: 227 LLIVARKVATQEGL-DKSGFRLVINDGKNGAQSVYHLHVHVL 349
           ++ V +    +  + D    RL  +       S+ HLH+HVL
Sbjct: 80  MMEVGKSTLQKNNVTDLEDIRLGFH--YPPFCSISHLHLHVL 119


>UniRef50_Q8F4J7 Cluster: HIT family hydrolase; n=4; Leptospira|Rep:
           HIT family hydrolase - Leptospira interrogans
          Length = 176

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
 Frame = +2

Query: 8   EVELAKSAAPGGDTIFGKILRK--EIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPIS 181
           +++ A+   P  D I   I RK  E+P   V E +  +   ++ P  P H++V P++ I 
Sbjct: 24  KLDYARGKRPDVDCILCGICRKDPEVPNLTVAETNFTIVSVNLYPYNPGHLIVFPKRHIL 83

Query: 182 QLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
              +   E+   +    + A  +  ++  +  GF L  N GKN   S+ H+H H++
Sbjct: 84  SYEELTKEEAMEIHEGTVKAISIL-KKLWNVQGFNLGYNLGKNSGGSIPHIHEHIV 138


>UniRef50_Q6SI40 Cluster: HIT family protein; n=1; uncultured
           bacterium 105|Rep: HIT family protein - uncultured
           bacterium 105
          Length = 167

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
 Frame = +2

Query: 26  SAAPGGDTIFGKILRKEIPAKFV-YEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGD 202
           SA    + IF +IL     +  + Y+ + C    ++ P +P H++V+P++ +  L+ A  
Sbjct: 15  SANRSRECIFCEILTDNSESTLLLYQGETCFIQLNLYPYSPGHLMVVPKRHLPSLTAATV 74

Query: 203 EDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGK-NGAQSVYHLHVHVL 349
           ++   +  L  +A +VA  E     G  + IN G   GA  V H+HVHV+
Sbjct: 75  QERMEIITLTALA-EVALTEVYAPQGLNVGINLGSAGGAGVVGHIHVHVV 123


>UniRef50_Q0UMA6 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 246

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
 Frame = +2

Query: 71  KEIPAKFVY-EDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLL-IVAR 244
           K  P  FV       VAF D+ P    H+LV  R+   +++  G  + + +G  L ++AR
Sbjct: 100 KTQPGSFVVLRSRDVVAFLDILPMVGGHLLVTTRQHKVKVADMGAVESREIGFWLPLLAR 159

Query: 245 KVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            V+   G+  S + +V N+G   AQ V H+H H++
Sbjct: 160 TVSLVTGV--SDYNIVQNNGARAAQVVPHVHFHII 192


>UniRef50_Q727L0 Cluster: HIT family protein; n=2;
           Deltaproteobacteria|Rep: HIT family protein -
           Desulfovibrio vulgaris (strain Hildenborough / ATCC
           29579 / NCIMB8303)
          Length = 142

 Score = 45.2 bits (102), Expect = 4e-04
 Identities = 23/94 (24%), Positives = 43/94 (45%)
 Frame = +2

Query: 92  VYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLD 271
           V E+  C A  D       H+L+IP++           +++    LL   R         
Sbjct: 22  VRENATCYAIRDKYAVTEGHLLIIPKRHTEDYFSLTQAEKRDADALLRELRDELASADAS 81

Query: 272 KSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWP 373
            SGF + +N G++  Q+++H H+H++  R+ + P
Sbjct: 82  ISGFNVGVNCGEDAGQTIFHAHIHLIPRRKGDTP 115


>UniRef50_Q4SA00 Cluster: Chromosome undetermined SCAF14693, whole
            genome shotgun sequence; n=6; Eukaryota|Rep: Chromosome
            undetermined SCAF14693, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 1438

 Score = 44.8 bits (101), Expect = 5e-04
 Identities = 27/71 (38%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
 Frame = +2

Query: 44   DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPI-SQLSKAGDEDEQLL 220
            D +F +I+R E     V+EDDQ VAF    P +P   +V+PRKP+ S + K  ++D +  
Sbjct: 948  DDLFSRIVRGEQQQWRVWEDDQHVAFLTPYPNSPGFTVVVPRKPLSSDIFKLSEDDYK-- 1005

Query: 221  GHLLIVARKVA 253
              L++   KVA
Sbjct: 1006 -GLILAVYKVA 1015


>UniRef50_A6S7H6 Cluster: Predicted protein; n=2;
           Sclerotiniaceae|Rep: Predicted protein - Botryotinia
           fuckeliana B05.10
          Length = 220

 Score = 44.8 bits (101), Expect = 5e-04
 Identities = 29/101 (28%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
 Frame = +2

Query: 74  EIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVA 253
           +IP+  +YE ++ +AF D+NP +  H LVIP+    +L    D+    L  +L V +K+ 
Sbjct: 105 DIPSFKLYESEKVLAFLDINPLSRGHALVIPKHHGEKLVDIPDDQ---LEEILPVVKKLV 161

Query: 254 TQEGLDKSGFRLVINDGKNGAQSVYHL-HVHVLGGRQLEWP 373
              G +   + ++ N+G+   Q V H+       G  + WP
Sbjct: 162 VATGAE--NYNVLQNNGRIAHQEVDHIPKPSTEEGMSIGWP 200


>UniRef50_P49776 Cluster: Bis(5'-nucleosyl)-tetraphosphatase
           [asymmetrical]; n=1; Schizosaccharomyces pombe|Rep:
           Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 182

 Score = 44.8 bits (101), Expect = 5e-04
 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
 Frame = +2

Query: 77  IPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKV-- 250
           + ++  Y      AF ++ P  P H+LVIP++ + +L    D     L  L    RKV  
Sbjct: 12  VGSQVFYRTKLSAAFVNLKPILPGHVLVIPQRAVPRLK---DLTPSELTDLFTSVRKVQQ 68

Query: 251 ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEW 370
             ++    S   + I DG +  Q+V H+HVH++  ++ ++
Sbjct: 69  VIEKVFSASASNIGIQDGVDAGQTVPHVHVHIIPRKKADF 108


>UniRef50_Q7F2H9 Cluster: P0432B10.9 protein; n=8;
           Magnoliophyta|Rep: P0432B10.9 protein - Oryza sativa
           subsp. japonica (Rice)
          Length = 401

 Score = 44.4 bits (100), Expect = 7e-04
 Identities = 20/33 (60%), Positives = 25/33 (75%)
 Frame = +2

Query: 218 LGHLLIVARKVATQEGLDKSGFRLVINDGKNGA 316
           +GHLL  A+ +A QE LD  GFR+VINDG NG+
Sbjct: 1   MGHLLYAAKTIAKQENLD-DGFRIVINDGPNGS 32


>UniRef50_Q2J8D3 Cluster: Histidine triad (HIT) protein; n=3;
           Frankia|Rep: Histidine triad (HIT) protein - Frankia sp.
           (strain CcI3)
          Length = 131

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 18/44 (40%), Positives = 27/44 (61%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPI 178
           ++F +I+  E+P + VY D+  VAF  + P  P H LV+PR  I
Sbjct: 3   SVFTRIINGELPGRIVYSDEHVVAFLTIAPIRPGHTLVVPRTEI 46


>UniRef50_Q5TVU2 Cluster: ENSANGP00000027488; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000027488 - Anopheles gambiae
           str. PEST
          Length = 121

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 27/79 (34%), Positives = 42/79 (53%)
 Frame = +2

Query: 113 VAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLV 292
           +A  D+ P+A  H LV+PRK I+ L +   +D  LL  +  +A+ V  + GLD   F   
Sbjct: 24  IAMRDLYPKARYHFLVLPRKNINTLHELTIDDVALLKDMYGLAQSVIKEGGLDTKQF--- 80

Query: 293 INDGKNGAQSVYHLHVHVL 349
            N G +    +  LH+HV+
Sbjct: 81  -NFGYHLKPHMKRLHLHVI 98


>UniRef50_Q3MMY7 Cluster: HINTW; n=4; Gallus gallus|Rep: HINTW -
           Gallus gallus (Chicken)
          Length = 82

 Score = 43.6 bits (98), Expect = 0.001
 Identities = 29/74 (39%), Positives = 36/74 (48%)
 Frame = +2

Query: 155 LVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHL 334
           L  P K +  LS A D    LLG L+IV  K A    L   GFR+ +    +   S Y  
Sbjct: 10  LAAPEKAVVGLSGAEDCGAPLLGRLMIVGEKCAANLSL-TDGFRMAVRYPPS-VPSDYRA 67

Query: 335 HVHVLGGRQLEWPP 376
            + +LGGRQL  PP
Sbjct: 68  RLCILGGRQLGQPP 81


>UniRef50_A1CID8 Cluster: HIT domain protein; n=1; Aspergillus
           clavatus|Rep: HIT domain protein - Aspergillus clavatus
          Length = 214

 Score = 43.6 bits (98), Expect = 0.001
 Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 4/116 (3%)
 Frame = +2

Query: 41  GDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLL 220
           G  +F     +E  A  V      +AF D+ P    H+LV+ R    +L   G E  +  
Sbjct: 36  GGAVFSTDTTQETHAHLVLSTTSVLAFLDIMPLTRGHVLVVTRDHYEKLGDMGVEVSR-- 93

Query: 221 GHLLIVARKVA-TQEGLDKSG---FRLVINDGKNGAQSVYHLHVHVLGGRQLEWPP 376
             L +++R V  T  G D+     + +V N+G   AQ V H+H HV+    L+  P
Sbjct: 94  EWLPVISRVVMKTIFGTDQESDWSWNVVQNNGIGAAQQVPHVHFHVIPRPPLDAAP 149


>UniRef50_Q88TZ2 Cluster: Cell-cycle regulation histidine triad
           protein; n=4; Lactobacillales|Rep: Cell-cycle regulation
           histidine triad protein - Lactobacillus plantarum
          Length = 122

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 25/98 (25%), Positives = 42/98 (42%)
 Frame = +2

Query: 80  PAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQ 259
           P  ++ E+D   AF D  P +P H+L+IP+   +            +  LL  A+     
Sbjct: 8   PLPYILENDLAAAFFDKKPVSPGHLLIIPKAHYATYFDVPTATRNAMLALLTQAKAYLDA 67

Query: 260 EGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWP 373
                 G+ + IN      Q+V H H+H++   Q + P
Sbjct: 68  HN-HPDGYNIGINVDPAAGQTVMHCHLHLIPRYQGDVP 104


>UniRef50_Q9Y8Y9 Cluster: HIT family protein; n=1; Aeropyrum
           pernix|Rep: HIT family protein - Aeropyrum pernix
          Length = 149

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           + IF +I++ E  A  VY+ +    F D  P +  H+LV+P +    +  A     ++  
Sbjct: 2   ECIFCRIVKGEAEAYTVYKGNGVTVFLDRYPASKGHLLVVPDEHYESIHTA---PPRVAA 58

Query: 224 HLLIVARKVAT--QEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            + + A  +A   +E        ++ N G+   Q ++H HVHV+
Sbjct: 59  KVWLAASAIARYYREKAGAPAVNVLTNSGRYAGQIIFHFHVHVI 102


>UniRef50_A2TZ69 Cluster: Putative cell-cycle regulation histidine
           triad protein; n=1; Polaribacter dokdonensis MED152|Rep:
           Putative cell-cycle regulation histidine triad protein -
           Polaribacter dokdonensis MED152
          Length = 121

 Score = 42.7 bits (96), Expect = 0.002
 Identities = 21/93 (22%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
 Frame = +2

Query: 74  EIPA-KFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKV 250
           +IP  + ++ ++      D  P +P H+L+I +       +   E+++ L  ++  A+++
Sbjct: 6   QIPKERIIFNNELFFIIKDKFPVSPGHLLIISKGIKKDFFELSLEEKEKLPKMIDKAKQL 65

Query: 251 ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
             QE  +  G+ + +N G +  Q+V+H H H++
Sbjct: 66  IKQE-YNPDGYNIGMNCGDSAGQTVFHFHCHII 97


>UniRef50_Q4P3W7 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 240

 Score = 42.7 bits (96), Expect = 0.002
 Identities = 21/64 (32%), Positives = 34/64 (53%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D  F +I+  +  A  VYED+  +AF D+ P    H LV+P+K + Q+S    +    L 
Sbjct: 53  DCAFCRIIAGQSAAYIVYEDEHNLAFLDILPLRRGHTLVVPKKHVEQVSHLDQQTAAWLS 112

Query: 224 HLLI 235
           + L+
Sbjct: 113 NALV 116


>UniRef50_Q979C0 Cluster: Histidine triad protein [HIT]; n=3;
           Thermoplasma|Rep: Histidine triad protein [HIT] -
           Thermoplasma volcanium
          Length = 157

 Score = 42.7 bits (96), Expect = 0.002
 Identities = 26/89 (29%), Positives = 41/89 (46%)
 Frame = +2

Query: 83  AKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQE 262
           A  V E++  +AF D  P  P H+LVIP++    +    D+   +    ++     A  E
Sbjct: 24  AAVVAENEYTIAFMDKAPVEPGHVLVIPKRHFINIFDI-DDFYYIEVQKMVKRVSKAVLE 82

Query: 263 GLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            L      +  N+G+   Q V H HVHV+
Sbjct: 83  ALSADALNVGQNNGRCANQIVMHYHVHVI 111


>UniRef50_Q7MKL5 Cluster: Diadenosine tetraphosphate hydrolase; n=7;
           Gammaproteobacteria|Rep: Diadenosine tetraphosphate
           hydrolase - Vibrio vulnificus (strain YJ016)
          Length = 138

 Score = 42.3 bits (95), Expect = 0.003
 Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGH 226
           TI  +I+ +EI +  VYE DQ +AF D +P    HIL+ P+   +Q     D  E +L  
Sbjct: 8   TIVEQIVNREIDSVIVYESDQVIAFADHDPINFGHILICPK---AQYRTFIDLPESVLFE 64

Query: 227 LLIVARKV--ATQEGLDKSGFRLVINDGK-NGAQSVYHLHVHV 346
           +  VAR +    +   +  G   + N+G+      + H H+H+
Sbjct: 65  ITDVARDLYKRIEAKFNPDGIGFMQNNGEAPHFNELDHYHLHI 107


>UniRef50_Q4FMD8 Cluster: Diadenosine tetraphosphate (Ap4A)
           hydrolase and other HIT family hydrolases; n=3;
           Bacteria|Rep: Diadenosine tetraphosphate (Ap4A)
           hydrolase and other HIT family hydrolases - Pelagibacter
           ubique
          Length = 144

 Score = 42.3 bits (95), Expect = 0.003
 Identities = 21/88 (23%), Positives = 41/88 (46%)
 Frame = +2

Query: 98  EDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKS 277
           E+D   A +D  P +  H L+IP++ +       D++     +L+   ++    +     
Sbjct: 33  ENDLAYASYDTYPVSEFHCLIIPKRHVVDYFDLNDDEVIACNNLIKQIKEEILLKDPAVK 92

Query: 278 GFRLVINDGKNGAQSVYHLHVHVLGGRQ 361
           GF +  N G    QS+ H H+H++  R+
Sbjct: 93  GFNIGTNAGVIAGQSILHCHIHLIPRRE 120


>UniRef50_Q23FD8 Cluster: HIT domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: HIT domain containing
           protein - Tetrahymena thermophila SB210
          Length = 162

 Score = 42.3 bits (95), Expect = 0.003
 Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
 Frame = +2

Query: 8   EVELAKSAAPGGDTIFGKILRKEIPAKFVYEDDQCV-AFHDVNPQAPTHILVIPRKPISQ 184
           +VE++ S        FGK    ++P   ++   + V A  ++ P  P H+LV  R+P+ +
Sbjct: 9   QVEMSASVVANLTVQFGK---SQLPLSQIFILRKNVFATTNLKPACPGHVLVASRRPVKR 65

Query: 185 LSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           L +    + + L     V +     E + K   ++ + DG +  Q++ H+H+H++
Sbjct: 66  LHEL--TEVETLDLWTTVQQVSRVMEQIHKFPCQIGVQDGTDAGQTIDHVHIHII 118


>UniRef50_Q7RY54 Cluster: Predicted protein; n=1; Neurospora
           crassa|Rep: Predicted protein - Neurospora crassa
          Length = 133

 Score = 41.9 bits (94), Expect = 0.004
 Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
 Frame = +2

Query: 134 PQAPTHILVIPRKPISQLSKA-GDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKN 310
           P +P H+L+ PR+  ++L+    DE  +L  +L I++  V    G+    + +V N+G  
Sbjct: 2   PLSPGHLLLCPRRHAAKLTDVLPDEAAELGRYLRILSEAVTRATGI--KDWNVVQNNGSA 59

Query: 311 GAQSVYHLHVHVL 349
            AQ V H+H H++
Sbjct: 60  AAQVVEHMHFHII 72


>UniRef50_A1C6L1 Cluster: HIT domain protein; n=9;
           Pezizomycotina|Rep: HIT domain protein - Aspergillus
           clavatus
          Length = 219

 Score = 41.9 bits (94), Expect = 0.004
 Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
 Frame = +2

Query: 116 AFHDVNPQAPTHILVIPRKPISQLSK-AGDEDEQLLGHLLIVARKVATQEGLDKSGFRLV 292
           A  ++ P  P H+LV PR+ + ++S     E   L   +  V R V    G   S   + 
Sbjct: 68  ALVNLKPILPGHVLVSPRRRVPRVSDLTAAETSDLFATVQRVGRVVERVYG--GSSLNIA 125

Query: 293 INDGKNGAQSVYHLHVHVL 349
           I DG    QSV H+H H++
Sbjct: 126 IQDGPEAGQSVAHVHAHII 144


>UniRef50_Q8FML1 Cluster: Putative uncharacterized protein; n=2;
           Corynebacterium|Rep: Putative uncharacterized protein -
           Corynebacterium efficiens
          Length = 159

 Score = 41.5 bits (93), Expect = 0.005
 Identities = 17/40 (42%), Positives = 25/40 (62%)
 Frame = +2

Query: 47  TIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIP 166
           T+F KI+  ++P +FV+  D  VAF  + P A  H LV+P
Sbjct: 20  TVFTKIIDGDLPGRFVFRSDSVVAFLSIEPLAYGHTLVVP 59


>UniRef50_Q28QE4 Cluster: Histidine triad (HIT) protein; n=1;
           Jannaschia sp. CCS1|Rep: Histidine triad (HIT) protein -
           Jannaschia sp. (strain CCS1)
          Length = 146

 Score = 41.5 bits (93), Expect = 0.005
 Identities = 21/68 (30%), Positives = 37/68 (54%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           D +F +I+    PA  V++D+ C+AF  + P      +VIP+  I   +   D  + L  
Sbjct: 4   DCVFCRIIAGTEPASIVHDDESCLAFMILRPIREGAFIVIPKVHIDHFT---DLPDDLAA 60

Query: 224 HLLIVARK 247
           HL+I+A++
Sbjct: 61  HLMIIAQR 68


>UniRef50_Q57WA7 Cluster: Putative uncharacterized protein; n=1;
           Trypanosoma brucei|Rep: Putative uncharacterized protein
           - Trypanosoma brucei
          Length = 258

 Score = 41.5 bits (93), Expect = 0.005
 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
 Frame = +2

Query: 68  RKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRK-PISQLSKAGDEDEQLLGHLLIVAR 244
           +K+  +  +Y+D QC+  +D  P++  H LVIP    +  LS        LL HL+ VA 
Sbjct: 65  QKKPTSHVLYKDPQCIIVNDAYPKSRLHCLVIPLDLSLDSLSALRPNHVPLLQHLMEVAE 124

Query: 245 KVA--TQE--GLDKSGFR-LVINDGKNGAQSVYHLHVHVLGGRQLEWP 373
           +    T+E    +++G + L    G +   S+  LH+H++  R L+ P
Sbjct: 125 QYVQFTREDAASNEAGIQALSFMTGFHSLPSLPQLHMHLI-SRDLDGP 171


>UniRef50_A7FTJ1 Cluster: HIT family protein; n=4; Clostridium
           botulinum|Rep: HIT family protein - Clostridium
           botulinum (strain ATCC 19397 / Type A)
          Length = 142

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 26/96 (27%), Positives = 43/96 (44%)
 Frame = +2

Query: 53  FGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLL 232
           F KI+ KE  A  VY++D    F    P    H+L+ P+K    L +  DE    +  + 
Sbjct: 10  FCKIINKEKKANIVYQNDLVCCFLAEEPINEGHMLIAPKKHYLDLDQMDDETAIEIMKVS 69

Query: 233 IVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHV 340
            +  KV  ++     G+ ++ N G       YH+H+
Sbjct: 70  KIMVKV-LKDTYKSDGYSIMQNGGSFNNVGHYHMHL 104


>UniRef50_Q558W0 Cluster: Putative uncharacterized protein; n=3;
           Dictyostelium discoideum|Rep: Putative uncharacterized
           protein - Dictyostelium discoideum AX4
          Length = 390

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 8/94 (8%)
 Frame = +2

Query: 92  VYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQ---- 259
           +Y DD+ VA  D  P+A  H LVIPR  I+ L +       +L H+  VA  +  +    
Sbjct: 245 LYYDDKTVAVLDKYPKAKHHYLVIPRVEINTLDELTPSFIPMLEHMYNVADAIINEIISK 304

Query: 260 ----EGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
               + L KS F+L    G +   S+  LH+H++
Sbjct: 305 DNDDDNLKKSDFKL----GFHAIPSMKRLHLHII 334


>UniRef50_Q4MZI5 Cluster: Bis(5'-nucleosyl)-tetraphosphatase
           (Asymmetrical), putative; n=2; Theileria|Rep:
           Bis(5'-nucleosyl)-tetraphosphatase (Asymmetrical),
           putative - Theileria parva
          Length = 173

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 22/78 (28%), Positives = 37/78 (47%)
 Frame = +2

Query: 116 AFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVI 295
           AF ++ P AP H LV P + + +      E E      L+     + ++  D +   ++I
Sbjct: 41  AFTNIKPFAPGHSLVSPLRVVPRYKDLTPE-EMFDWSCLVQVVAESLEKMYDSTSCSIII 99

Query: 296 NDGKNGAQSVYHLHVHVL 349
            DG    Q++ HLH HV+
Sbjct: 100 QDGPEAGQTIPHLHAHVI 117


>UniRef50_A6QVS2 Cluster: Predicted protein; n=1; Ajellomyces
           capsulatus NAm1|Rep: Predicted protein - Ajellomyces
           capsulatus NAm1
          Length = 243

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
 Frame = +2

Query: 68  RKEIP-AKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVAR 244
           R + P A  +      +AF D+ P    H+LVI R    +L   G E  + LG  L +  
Sbjct: 64  RSQAPQAHLILSTKHVLAFLDIMPLTRGHVLVISRDHHEKLGNVGVEVGKELGKWLPILS 123

Query: 245 KVATQEGL---------DKSGFRLVINDGKNGAQSVYHLHVHVL 349
           +  T+  L         D + + +V N+G   +Q++ H+H H++
Sbjct: 124 RAVTRTVLGTELDSRREDPAQWNVVQNNGPRASQTIPHVHFHII 167


>UniRef50_A1RXN8 Cluster: Histidine triad (HIT) protein; n=1;
           Thermofilum pendens Hrk 5|Rep: Histidine triad (HIT)
           protein - Thermofilum pendens (strain Hrk 5)
          Length = 167

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
 Frame = +2

Query: 11  VELAKSAAPGGDTIFGKILRKEIPAKFV-YEDDQCVAFHDVNPQAPTHILVIPRKPISQL 187
           +E AK     G  I   +   E+    V Y+ ++ +   +  P    H+LV P + ++  
Sbjct: 13  IEYAKIERGEGCFICKAVESSELEENLVVYKGEKIIVMLNRYPYNTGHLLVAPTRHVADF 72

Query: 188 SKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGK-NGAQSVYHLHVHVL 349
           S+  DE+   L   + ++ ++  ++ L   GF + +N G+  GA    HLHVHV+
Sbjct: 73  SQLSDEELFSLAKAVSLSLEL-LKKALSPDGFNVGVNLGRVAGAGLESHLHVHVV 126


>UniRef50_Q7MA74 Cluster: HIT FAMILY PROTEIN; n=3;
           Helicobacteraceae|Rep: HIT FAMILY PROTEIN - Wolinella
           succinogenes
          Length = 162

 Score = 40.7 bits (91), Expect = 0.009
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
 Frame = +2

Query: 86  KFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARK-VATQE 262
           K  Y DD C+A  +  P  P H ++IP   +   +   +E      HL  +A+K VA  E
Sbjct: 37  KVFYRDDLCLAVMNKFPYTPGHFMIIPHAHVDTPTLLSEESWL---HLSRLAQKGVALLE 93

Query: 263 GLDKSGFRLVINDGKNGAQSV-YHLHVHVL 349
                G    IN  ++G   +  HLH+H++
Sbjct: 94  AFGAHGVNYGINIKRSGGAGIPDHLHLHLV 123


>UniRef50_A7HHG6 Cluster: Type III restriction protein res subunit;
           n=3; Myxococcaceae|Rep: Type III restriction protein res
           subunit - Anaeromyxobacter sp. Fw109-5
          Length = 1418

 Score = 40.7 bits (91), Expect = 0.009
 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
 Frame = +2

Query: 74  EIPAK-FVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKV 250
           +IP + ++  ++   A  D  P    H L+I R+ +     A  ++++ +  L+ V +  
Sbjct: 7   DIPEREWLVSNELAFAIRDTFPVTDGHTLIIARRQVRDWFDATRDEQRAMLDLVEVVKLQ 66

Query: 251 ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
              E    +G+ +  N G +  Q+V HLHVHV+
Sbjct: 67  LDAEH-QPAGYNVGFNVGVHAGQTVMHLHVHVI 98


>UniRef50_Q8SR62 Cluster: BIS 5'-ADENOSYL TRIPHOSPHATASE OF THE HIT
           FAMILY; n=1; Encephalitozoon cuniculi|Rep: BIS
           5'-ADENOSYL TRIPHOSPHATASE OF THE HIT FAMILY -
           Encephalitozoon cuniculi
          Length = 155

 Score = 40.7 bits (91), Expect = 0.009
 Identities = 26/77 (33%), Positives = 40/77 (51%)
 Frame = +2

Query: 119 FHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVIN 298
           F ++ P  P HIL  P     +L +   E+   L + + VA K   +E  D  GF + I 
Sbjct: 23  FTNIRPFLPLHILASPISRKQRLYELTAEETSDLFNSVRVAMK-GLRELCD--GFTINIQ 79

Query: 299 DGKNGAQSVYHLHVHVL 349
           DG+   Q+V+H HVH++
Sbjct: 80  DGECAGQTVFHAHVHIV 96


>UniRef50_A3CVL7 Cluster: Histidine triad (HIT) protein; n=1;
           Methanoculleus marisnigri JR1|Rep: Histidine triad (HIT)
           protein - Methanoculleus marisnigri (strain ATCC 35101 /
           DSM 1498 / JR1)
          Length = 109

 Score = 40.3 bits (90), Expect = 0.012
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
 Frame = +2

Query: 143 PTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVAT--QEGLDKSGFRLVINDGKNGA 316
           P H+L+IP + ++    A D +   L  LL + R+  T   +     G+ + +N  K   
Sbjct: 18  PGHLLIIPYRHVADFFDATDAE---LAALLALVREAKTLLDDRFHPDGYNIGVNVRKAAG 74

Query: 317 QSVYHLHVHVL 349
           Q+V HLH+HV+
Sbjct: 75  QTVMHLHLHVI 85


>UniRef50_P49775 Cluster: Hit family protein 2; n=2; Saccharomyces
           cerevisiae|Rep: Hit family protein 2 - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 206

 Score = 40.3 bits (90), Expect = 0.012
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
 Frame = +2

Query: 95  YEDDQCVAFHDVNPQAPTHILVIP-RKPISQLSKAG-DEDEQLLGHLLIVARKVATQEGL 268
           Y+     A  ++ P  P H+L++P R  +  LS     E +     L ++ R +  Q   
Sbjct: 18  YKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQYKA 77

Query: 269 DKSGFRLVINDGKNGAQSVYHLHVHVL 349
           D     + I DG    QSV HLH H++
Sbjct: 78  DS--INVAIQDGPEAGQSVPHLHTHII 102


>UniRef50_Q3MMY8 Cluster: HINTW; n=5; Phasianidae|Rep: HINTW -
           Phasianus colchicus (Ring-necked pheasant) (Common
           pheasant)
          Length = 82

 Score = 39.9 bits (89), Expect = 0.015
 Identities = 27/74 (36%), Positives = 37/74 (50%)
 Frame = +2

Query: 155 LVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHL 334
           L    K + +LS+A D    L   L IV  K A   GL  +GF++ +    +G  S Y  
Sbjct: 10  LAAREKAVVKLSEAEDSGAPLHRRLKIVGEKCAANLGLT-NGFQMAVRYPPSGP-SDYRT 67

Query: 335 HVHVLGGRQLEWPP 376
            + +LGGRQL  PP
Sbjct: 68  RLCILGGRQLGQPP 81


>UniRef50_Q97IN2 Cluster: HIT family hydrolase; n=4; Bacteria|Rep:
           HIT family hydrolase - Clostridium acetobutylicum
          Length = 122

 Score = 39.9 bits (89), Expect = 0.015
 Identities = 22/86 (25%), Positives = 42/86 (48%)
 Frame = +2

Query: 92  VYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLD 271
           + E+    A  D NP    H L+I ++      +A  E+   +  LL  A+ +   +  +
Sbjct: 17  ICENKLAFAILDKNPVNEGHTLIITKRHFPFFFEASGEEVMAMYSLLHEAKGILDIQ-YE 75

Query: 272 KSGFRLVINDGKNGAQSVYHLHVHVL 349
            SG+ + +N G    Q+V H+H+H++
Sbjct: 76  PSGYNIGVNVGYYAGQTVKHMHIHLI 101


>UniRef50_Q9NQE9 Cluster: Histidine triad nucleotide binding protein
           3; n=22; Euteleostomi|Rep: Histidine triad nucleotide
           binding protein 3 - Homo sapiens (Human)
          Length = 182

 Score = 39.9 bits (89), Expect = 0.015
 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
 Frame = +2

Query: 98  EDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGL-DK 274
           E++  + F D+ P A  H LV+P+K I        +  +L+ +++ V + +  +    D 
Sbjct: 67  ENEDLICFKDIKPAATHHYLVVPKKHIGNCRTLRKDQVELVENMVTVGKTILERNNFTDF 126

Query: 275 SGFRLVINDGKNGAQSVYHLHVHVL 349
           +  R+  +       S+ HLH+HVL
Sbjct: 127 TNVRMGFH--MPPFCSISHLHLHVL 149


>UniRef50_Q8SRE4 Cluster: HIT FAMILY PROTEIN; n=1; Encephalitozoon
           cuniculi|Rep: HIT FAMILY PROTEIN - Encephalitozoon
           cuniculi
          Length = 131

 Score = 39.9 bits (89), Expect = 0.015
 Identities = 30/100 (30%), Positives = 49/100 (49%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHL 229
           IF  + RK   A  +YE D+  A  D  P +  H LVIP+     L     E+   L  +
Sbjct: 5   IFCTLYRKG--ANIIYETDRLFALIDRYPLSKGHFLVIPKAHHPYLHNYKPEE---LSGV 59

Query: 230 LIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           L   R +  + G ++  + ++ N+G +  Q V+H+H HV+
Sbjct: 60  LDTIRHLVQKFGFER--YNILQNNGNH--QEVFHVHFHVI 95


>UniRef50_A7I5E0 Cluster: Histidine triad (HIT) protein; n=1;
           Candidatus Methanoregula boonei 6A8|Rep: Histidine triad
           (HIT) protein - Methanoregula boonei (strain 6A8)
          Length = 149

 Score = 39.9 bits (89), Expect = 0.015
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
 Frame = +2

Query: 86  KFVYEDDQCVAFHDVNPQAPTHILVIP-RKPISQLSKAGDEDEQLLGHLLIVARKVATQE 262
           + V  +D C A  D  P +  H+LV+P R      S   +E  +++   LI A K   +E
Sbjct: 15  EIVARNDLCYARWDRFPASKGHLLVLPFRHTPYFFSMTKEERREMIA--LIEACKQVIEE 72

Query: 263 GLDKSGFRLVINDGKNGAQSVYHLHVH 343
                G+ + IN+G    Q + H H H
Sbjct: 73  NFVPDGYTIGINEGLAAGQVILHCHCH 99


>UniRef50_Q9IB93 Cluster: Wpkci; n=20; Neognathae|Rep: Wpkci -
           Coturnix coturnix japonica (Japanese quail)
          Length = 130

 Score = 39.5 bits (88), Expect = 0.020
 Identities = 36/129 (27%), Positives = 52/129 (40%), Gaps = 5/129 (3%)
 Frame = +2

Query: 5   GEVELAKSAAPGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNP-----QAPTHILVIPR 169
           G +  + +A  GG  + GK+ R+E  A  + E++       +       Q     L  P 
Sbjct: 3   GGIVRSPAAWLGGAALMGKVARQEFSASVIREEEPLRTGSTLRSMISHRQLLGFFLAAPE 62

Query: 170 KPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
           K + +LS A      LLGHL IV  K A   G    GFR+      +         + +L
Sbjct: 63  KAVVRLSGAEVSGAPLLGHLKIVGEKCAANLG-PTDGFRMAARYPPSDPSDCC-ARLCLL 120

Query: 350 GGRQLEWPP 376
            G QL  PP
Sbjct: 121 VGHQLGQPP 129


>UniRef50_Q0V966 Cluster: Zgc:136256; n=4; Danio rerio|Rep:
           Zgc:136256 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 160

 Score = 39.5 bits (88), Expect = 0.020
 Identities = 20/51 (39%), Positives = 27/51 (52%)
 Frame = +2

Query: 98  EDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKV 250
           ED+  V F D+NP AP H LVIP+K I        +D  L+  +  + R V
Sbjct: 41  EDEDFVCFRDINPGAPHHYLVIPKKHIYSCLSLYADDISLVRAMAEMGRNV 91


>UniRef50_Q2BE03 Cluster: Cell-cycle regulation histidine triad, Hit
           family protein; n=1; Bacillus sp. NRRL B-14911|Rep:
           Cell-cycle regulation histidine triad, Hit family
           protein - Bacillus sp. NRRL B-14911
          Length = 146

 Score = 39.5 bits (88), Expect = 0.020
 Identities = 26/110 (23%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDE---- 211
           D +  ++  K  P   +YE++      D +P    H+L++P+K   +L+   +E      
Sbjct: 3   DCLGCRLAHKSEPVFIIYENNLISCILDHDPFGEGHVLILPKKHAEELTDLDEESAVAVF 62

Query: 212 QLLGHLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQ 361
           +   HL  V +++   +G+     R + ND       + H H+HV+  RQ
Sbjct: 63  RAAQHLSTVIKRLYKPDGITLCQKRGIFND-------LNHFHLHVIPRRQ 105


>UniRef50_A3ESI2 Cluster: Diadenosine tetraphosphate hydrolase; n=2;
           Bacteria|Rep: Diadenosine tetraphosphate hydrolase -
           Leptospirillum sp. Group II UBA
          Length = 179

 Score = 39.5 bits (88), Expect = 0.020
 Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
 Frame = +2

Query: 92  VYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLD 271
           +Y    C    +  P    H++V+P      LS    E  + +  LL    K+  +E  +
Sbjct: 42  LYRTTLCYIVLNAFPYTSGHLMVVPHAHGGSLSSQNPESLREMMDLLGACEKILEKE-YN 100

Query: 272 KSGFRLVINDGKN-GAQSVYHLHVHVL 349
            +G+ + IN GK+ GA    HLH H+L
Sbjct: 101 PTGYNIGINVGKSAGAGIQDHLHAHIL 127


>UniRef50_Q17CS4 Cluster: Nitrilase, putative; n=3; Culicidae|Rep:
           Nitrilase, putative - Aedes aegypti (Yellowfever
           mosquito)
          Length = 477

 Score = 39.5 bits (88), Expect = 0.020
 Identities = 24/101 (23%), Positives = 48/101 (47%), Gaps = 1/101 (0%)
 Frame = +2

Query: 74  EIPAKFV-YEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKV 250
           +IP   V Y  + C AF ++    P H+LV  ++  +++      +       +   +KV
Sbjct: 336 DIPNDTVFYSSELCYAFVNIRCVVPGHVLVSTKRWAARMPDLTPAEINDFFQTVCKVQKV 395

Query: 251 ATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWP 373
           A +     S   + + DG +  Q+V+H+H HV+   + ++P
Sbjct: 396 A-ESLYGGSSATVTVQDGPDAGQTVFHVHCHVMPRHKGDFP 435


>UniRef50_A2E0S0 Cluster: HIT domain containing protein; n=1;
           Trichomonas vaginalis G3|Rep: HIT domain containing
           protein - Trichomonas vaginalis G3
          Length = 135

 Score = 39.5 bits (88), Expect = 0.020
 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
 Frame = +2

Query: 77  IPAKFV-YEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVA 253
           IP + + YE +   AF ++ P    H+L+ P++ +       D ++  L +     R   
Sbjct: 13  IPKEHIFYESELSFAFVNLRPACEGHVLISPKRVVQFFDLLTDAEKLDLLNTATHVRDTM 72

Query: 254 TQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            +  +   G  + I DG    Q+V H+H HV+
Sbjct: 73  -KASMHTEGCAMTIQDGPAAGQTVPHVHFHVI 103


>UniRef50_A4RGB9 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 201

 Score = 39.5 bits (88), Expect = 0.020
 Identities = 23/79 (29%), Positives = 39/79 (49%)
 Frame = +2

Query: 113 VAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLV 292
           VAF D+ P +  H+L+ PR    +L+     + + LG  + V  + A         + +V
Sbjct: 63  VAFLDIMPLSRGHVLLCPRAHRRKLTAVTAAEARELGFFVRVLSE-AVMRATGVGDWNVV 121

Query: 293 INDGKNGAQSVYHLHVHVL 349
            N+G   AQ V H+H H++
Sbjct: 122 QNNGAAAAQVVPHMHFHII 140


>UniRef50_Q74ND2 Cluster: NEQ213; n=1; Nanoarchaeum equitans|Rep:
           NEQ213 - Nanoarchaeum equitans
          Length = 188

 Score = 39.5 bits (88), Expect = 0.020
 Identities = 24/102 (23%), Positives = 50/102 (49%)
 Frame = +2

Query: 44  DTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLG 223
           + +F  I   +IP+  +YED+  V   D+ P  P  +L+IP++ ++ +    + D ++L 
Sbjct: 2   ECLFCAIASGQIPSYKIYEDNDLVVVLDIYPAHPGQLLIIPKQHVTFI---WELDREILH 58

Query: 224 HLLIVARKVATQEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            +L  +   A   G       + I +G    Q V H+ ++++
Sbjct: 59  KILEASVIFAKVIGSIYPSVTIYIPNGPYAGQRVPHVAIYII 100


>UniRef50_A0B7E7 Cluster: Histidine triad (HIT) protein; n=1;
           Methanosaeta thermophila PT|Rep: Histidine triad (HIT)
           protein - Methanosaeta thermophila (strain DSM 6194 /
           PT) (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 141

 Score = 39.5 bits (88), Expect = 0.020
 Identities = 17/43 (39%), Positives = 28/43 (65%)
 Frame = +2

Query: 50  IFGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPI 178
           +F +I+R + PA  + ED+  +A  D+NP A  H LVIP++ +
Sbjct: 6   VFCRIVRGDEPAHIIDEDELSMAILDINPLARGHCLVIPKRHV 48


>UniRef50_Q6F6S5 Cluster: Putative histidine triad family protein;
           n=1; Acinetobacter sp. ADP1|Rep: Putative histidine
           triad family protein - Acinetobacter sp. (strain ADP1)
          Length = 122

 Score = 39.1 bits (87), Expect = 0.027
 Identities = 21/84 (25%), Positives = 39/84 (46%)
 Frame = +2

Query: 98  EDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKS 277
           ++D  V   +  P +  H ++IP + +    +  D++ + L  LL +AR           
Sbjct: 21  KNDFGVILPEAKPLSKGHSIIIPIRHVGSFFEVTDKERKSLMSLLELARNELKIRH-QPD 79

Query: 278 GFRLVINDGKNGAQSVYHLHVHVL 349
           GF +  NDG    +   HLH+H++
Sbjct: 80  GFHVAFNDGDVFGEESEHLHIHII 103


>UniRef50_A6G0U4 Cluster: Helicase, DEAD/DEAH family protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Helicase, DEAD/DEAH
           family protein - Plesiocystis pacifica SIR-1
          Length = 128

 Score = 39.1 bits (87), Expect = 0.027
 Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
 Frame = +2

Query: 92  VYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGD-EDEQLLGHLLIVARKVATQEGL 268
           V++  +  A  D  P +P H LVI ++ +    +  + E  ++   +  V R+++ +  L
Sbjct: 19  VFDSARVYAIADAFPVSPGHTLVISKRHVPSYFELDEAEQREMWAAVATVQRELSRR--L 76

Query: 269 DKSGFRLVINDGKNGAQSVYHLHVHVL 349
              GF +  N G    Q++ H H+HV+
Sbjct: 77  LPGGFNVGFNVGAVAGQTIMHAHIHVI 103


>UniRef50_A3Z7E0 Cluster: HIT family protein; n=6;
           Synechococcus|Rep: HIT family protein - Synechococcus
           sp. RS9917
          Length = 314

 Score = 39.1 bits (87), Expect = 0.027
 Identities = 23/96 (23%), Positives = 43/96 (44%)
 Frame = +2

Query: 86  KFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEG 265
           + +  ++  V   D  P    H LVIP + ++   +    +   +  LL   R+      
Sbjct: 203 RVLLRNELAVCIADAYPVTEGHSLVIPCRHVADGMELHQPEWNAVTALLKQRRQDLELAD 262

Query: 266 LDKSGFRLVINDGKNGAQSVYHLHVHVLGGRQLEWP 373
              SGF + +N G++  Q+V H H H++  R+ + P
Sbjct: 263 ASISGFNIGLNSGESAGQTVMHAHWHLIPRRKGDMP 298


>UniRef50_A1UF80 Cluster: Histidine triad (HIT) protein; n=5;
           Mycobacterium|Rep: Histidine triad (HIT) protein -
           Mycobacterium sp. (strain KMS)
          Length = 244

 Score = 39.1 bits (87), Expect = 0.027
 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
 Frame = +2

Query: 92  VYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGD-EDEQLLGHLLIVARKVATQEGL 268
           V   DQ  A  ++ P  P H++V+P + +S+L    D E  +L+ +     R +      
Sbjct: 103 VARGDQVYAVLNLYPYNPGHLMVVPYRRVSELEDLTDAESAELMSYTQKAIRVIKAVS-- 160

Query: 269 DKSGFRLVINDGKN-GAQSVYHLHVHVL 349
              GF + +N G++ G     HLH+HV+
Sbjct: 161 RPHGFNVGLNLGQSAGGSLAEHLHMHVV 188


>UniRef50_Q54DF5 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 166

 Score = 39.1 bits (87), Expect = 0.027
 Identities = 23/79 (29%), Positives = 41/79 (51%)
 Frame = +2

Query: 113 VAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLDKSGFRLV 292
           + F+D  P+A  H L+ PR+ I  +     +D  +L  +  VA ++  ++   +SG  +V
Sbjct: 53  IVFNDRTPKATVHYLICPREHIVSIKTLTQKDIPVLVEMKQVADQLIAEKFPGQSG--IV 110

Query: 293 INDGKNGAQSVYHLHVHVL 349
           +        SV HLH+H+L
Sbjct: 111 LGFHSPPFYSVKHLHLHLL 129


>UniRef50_Q18227 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 175

 Score = 39.1 bits (87), Expect = 0.027
 Identities = 29/100 (29%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
 Frame = +2

Query: 68  RKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARK 247
           +KE+  K   E+  CV  +D+ P+A  H LV+ ++ I++ +     D  LL  +    R+
Sbjct: 20  KKELQLK---ENKSCVVINDIKPKAKNHYLVLSKQHIAKPTDLTVADVPLLEEMEKTGRE 76

Query: 248 VATQEGLDKSGFRLVINDG-KNGAQ-----SVYHLHVHVL 349
           +  +E L K G    + D  + G       SV+HLH+H++
Sbjct: 77  L-LREHLKKKGEADTVEDMLRIGFHLPPLLSVHHLHMHII 115


>UniRef50_Q8EIE9 Cluster: Putative uncharacterized protein; n=1;
           Shewanella oneidensis|Rep: Putative uncharacterized
           protein - Shewanella oneidensis
          Length = 254

 Score = 38.7 bits (86), Expect = 0.035
 Identities = 24/76 (31%), Positives = 35/76 (46%)
 Frame = +2

Query: 77  IPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVAT 256
           +PA+F+YE D    F +V      HI +I  +P    + AG  D+ ++   L+   K   
Sbjct: 27  MPAEFIYEKDVLAQFQEVIETC--HIYIIGYEPRVDFTGAGQVDDYMVLDFLVAGVKRQL 84

Query: 257 QEGLDKSGFRLVINDG 304
           Q G    G R V  DG
Sbjct: 85  QFGPIPEGVRFVNEDG 100


>UniRef50_Q0IT83 Cluster: Os11g0295000 protein; n=2; Oryza sativa
           (japonica cultivar-group)|Rep: Os11g0295000 protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 104

 Score = 38.7 bits (86), Expect = 0.035
 Identities = 18/38 (47%), Positives = 23/38 (60%)
 Frame = +2

Query: 32  APGGDTIFGKILRKEIPAKFVYEDDQCVAFHDVNPQAP 145
           A G   +F +I+R E PA  VYEDD C+   D +P AP
Sbjct: 66  AEGKSCVFCRIIRGEAPAFKVYEDDVCLCILDSHPLAP 103


>UniRef50_Q4PA08 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 196

 Score = 38.7 bits (86), Expect = 0.035
 Identities = 23/88 (26%), Positives = 37/88 (42%)
 Frame = +2

Query: 86  KFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEG 265
           + V ED++ + F D +P A  H+LVIPR  I+ +        +L+  +  +  K      
Sbjct: 58  RIVIEDEKLICFTDRSPGAAIHLLVIPRNHIANVQSLTHNHTELVRQMQALGNKALDLVS 117

Query: 266 LDKSGFRLVINDGKNGAQSVYHLHVHVL 349
                            +SV HLH+H L
Sbjct: 118 TSNCAPERRFGFHIPPIRSVDHLHLHCL 145


>UniRef50_A2Q8C2 Cluster: Similarity: the HIT; n=1; Aspergillus
           niger|Rep: Similarity: the HIT - Aspergillus niger
          Length = 304

 Score = 38.7 bits (86), Expect = 0.035
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
 Frame = +2

Query: 35  PGGDT-IFGKILR-KEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPI-SQLSKAGDE 205
           P  DT +F  I+R  E P   ++ED+  VAF    P  P   +++PR  + S +   G+E
Sbjct: 150 PSSDTNLFANIIRGTEHPQWRIWEDESRVAFLTPYPNTPGFTVLVPRTHLGSDIFALGEE 209

Query: 206 D-EQLLGHLLIVARKVATQEGLDKSG 280
           D E L+G    V R +    G+ + G
Sbjct: 210 DFEGLMGAAWTVGRVLMEALGVGRCG 235


>UniRef50_Q9JIX3 Cluster: Bis(5'-adenosyl)-triphosphatase; n=11;
           Eukaryota|Rep: Bis(5'-adenosyl)-triphosphatase - Rattus
           norvegicus (Rat)
          Length = 150

 Score = 38.7 bits (86), Expect = 0.035
 Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
 Frame = +2

Query: 53  FGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLL 232
           FG+ L K  P+    + +   A  +  P  P H+L+ P +P+ +      ++   +  L 
Sbjct: 5   FGQHLIK--PSVVFLKTELSFALVNRKPVVPGHVLMCPLRPVERFRDLRPDE---VADLF 59

Query: 233 IVARKVAT--QEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
            V ++V T  ++    +     + DG    Q+V H+HVH+L
Sbjct: 60  QVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHIL 100


>UniRef50_P49789 Cluster: Bis(5'-adenosyl)-triphosphatase; n=31;
           Eumetazoa|Rep: Bis(5'-adenosyl)-triphosphatase - Homo
           sapiens (Human)
          Length = 147

 Score = 38.3 bits (85), Expect = 0.047
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
 Frame = +2

Query: 53  FGKILRKEIPAKFVYEDDQCVAFHDVNPQAPTHILVIPRKPISQLSKAGDEDEQLLGHLL 232
           FG+ L K  P+    + +   A  +  P  P H+LV P +P+ +      ++   +  L 
Sbjct: 5   FGQHLIK--PSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDE---VADLF 59

Query: 233 IVARKVAT--QEGLDKSGFRLVINDGKNGAQSVYHLHVHVL 349
              ++V T  ++    +     + DG    Q+V H+HVHVL
Sbjct: 60  QTTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVL 100


>UniRef50_UPI00006CEB92 Cluster: HIT domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: HIT domain containing
           protein - Tetrahymena thermophila SB210
          Length = 142

 Score = 37.9 bits (84), Expect = 0.062
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
 Frame = +2

Query: 95  YEDDQCVAFHDVN-PQAPTHILVIPRKPISQLSKAGDEDEQLLGHLLIVARKVATQEGLD 271
           YEDD+  AF D+N   +  HIL+ P++ I  +++    D +L+  L  V  +   QE   
Sbjct: 25  YEDDEIFAFEDINIASSKRHILICPKRHIKNVNELNYLDIELVKRLEQVGIQ-TLQESHP 83

Query: 272 KSGFRLVINDGKNGAQSVYHLHVH 343
              +R   +       S+ HLH+H
Sbjct: 84  NQQYRFGYHSPP--LNSIDHLHLH 105


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 440,067,018
Number of Sequences: 1657284
Number of extensions: 9359545
Number of successful extensions: 28206
Number of sequences better than 10.0: 332
Number of HSP's better than 10.0 without gapping: 27143
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28014
length of database: 575,637,011
effective HSP length: 91
effective length of database: 424,824,167
effective search space used: 14444021678
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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