Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0001_N15
(584 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 256 4e-67
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 215 8e-55
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 196 4e-49
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 189 4e-47
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 188 1e-46
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 186 3e-46
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 186 4e-46
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 182 4e-45
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 182 7e-45
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 182 7e-45
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 180 3e-44
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 179 4e-44
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 177 2e-43
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 176 4e-43
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 175 8e-43
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 174 1e-42
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 173 3e-42
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 173 3e-42
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 168 1e-40
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 167 1e-40
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 167 1e-40
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 167 2e-40
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 166 3e-40
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 166 3e-40
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 166 4e-40
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 166 4e-40
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 165 5e-40
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 165 7e-40
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 164 1e-39
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 163 3e-39
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 161 1e-38
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 157 2e-37
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 155 7e-37
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 155 7e-37
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 153 3e-36
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 148 8e-35
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 148 1e-34
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 147 2e-34
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 146 4e-34
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 140 2e-32
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 136 3e-31
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 133 3e-30
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 132 8e-30
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 132 8e-30
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 128 1e-28
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 127 2e-28
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 105 8e-22
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 85 9e-16
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 74 2e-12
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 70 4e-11
UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n... 59 7e-08
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 53 6e-06
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 52 8e-06
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 41 0.019
UniRef50_A5WHB8 Cluster: Short-chain dehydrogenase/reductase SDR... 37 0.30
UniRef50_A5WES0 Cluster: UvrD/REP helicase; n=1; Psychrobacter s... 36 0.70
UniRef50_A6W2K1 Cluster: Carbamoyl-phosphate synthase, large sub... 36 0.93
UniRef50_A6PN14 Cluster: D-alanine--D-alanine ligase precursor; ... 36 0.93
UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IM... 35 1.2
UniRef50_UPI000034F4E7 Cluster: unknown protein; n=1; Arabidopsi... 34 2.2
UniRef50_A5BDL1 Cluster: Putative uncharacterized protein; n=1; ... 34 2.2
UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase pyrimidine... 34 2.2
UniRef50_Q28PE6 Cluster: Methyltransferase type 12; n=1; Jannasc... 34 2.8
UniRef50_A4X3R2 Cluster: Putative uncharacterized protein; n=1; ... 34 2.8
UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chai... 34 2.8
UniRef50_A6NS15 Cluster: Putative uncharacterized protein; n=1; ... 33 3.8
UniRef50_Q5A9A3 Cluster: Putative uncharacterized protein; n=1; ... 33 3.8
UniRef50_A6Q2L8 Cluster: Flagellar P-ring protein FlgI; n=1; Nit... 33 5.0
UniRef50_A4BEW0 Cluster: Putative uncharacterized protein; n=1; ... 33 5.0
UniRef50_UPI00015545E8 Cluster: PREDICTED: similar to smooth mus... 33 6.6
UniRef50_A1ANW7 Cluster: Glycosyl transferase, group 1; n=2; Des... 33 6.6
UniRef50_A5BSI2 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6
UniRef50_A4S0E5 Cluster: Predicted protein; n=2; Ostreococcus|Re... 33 6.6
UniRef50_A7EYF3 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6
UniRef50_Q2JDI9 Cluster: Glycine--tRNA ligase; n=21; cellular or... 32 8.7
UniRef50_O14102 Cluster: Spliceosome-associated protein 49; n=2;... 32 8.7
UniRef50_O27077 Cluster: Carbamoyl-phosphate synthase large chai... 32 8.7
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 256 bits (626), Expect = 4e-67
Identities = 127/188 (67%), Positives = 149/188 (79%)
Frame = +2
Query: 20 GKLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGG 199
G+LAL SVSDKTGL+ + L+ +GL LV SGGTA ALR+AGL+V DVS++T PEMLGG
Sbjct: 4 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63
Query: 200 RVKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
RVKTLHPAVHAGILAR D DM R +F +I VV CNLYPFV+TVA VTV +AVE
Sbjct: 64 RVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQ 123
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGGVTLLRAAAKNH RVTV+C+P DY V+ EM+ S+ TS ETR++LALKAFTHT+
Sbjct: 124 IDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTA 183
Query: 560 EYDLAISD 583
+YD AISD
Sbjct: 184 QYDEAISD 191
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 215 bits (524), Expect = 8e-55
Identities = 107/165 (64%), Positives = 124/165 (75%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
ALLSVSDKTGL+ K L ++GL LV SGGTA LR+AG +V DVS++T PEMLGGRVK
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVK 60
Query: 209 TLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENIDI 388
TLHPAVH GILAR S D DM++ + +I VVVCNLYPFV+TV+ VTV DAVE IDI
Sbjct: 61 TLHPAVHGGILARKSPADTADMEKLGYSLIRVVVCNLYPFVKTVSNPSVTVEDAVEQIDI 120
Query: 389 GGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETR 523
GGVTLLRAAAKNH RVTV+CDP DY + EM+ S T + TR
Sbjct: 121 GGVTLLRAAAKNHARVTVVCDPADYPRVAEEMEGSGSRDTPSRTR 165
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 196 bits (477), Expect = 4e-49
Identities = 97/185 (52%), Positives = 126/185 (68%)
Frame = +2
Query: 26 LALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRV 205
L L SVSDKTGL L G + SGGTA L+ AG+ V +VS+ T +PE+LGGRV
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRV 62
Query: 206 KTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
KTLHP +H GILAR + D+ ++K F I +V+ NLYPF +T++ D T +D +ENID
Sbjct: 63 KTLHPMIHGGILARDTKEDRAELKALGFSGIDIVIANLYPFEKTISSPDSTESDCIENID 122
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGGV LLRAAAKN+ RVTVICDP DYD + +E++ K + S R+RLA+KAF + Y
Sbjct: 123 IGGVALLRAAAKNYSRVTVICDPADYDEVSSEIE--KTGEISLSLRKRLAIKAFDLCTRY 180
Query: 566 DLAIS 580
D AI+
Sbjct: 181 DAAIT 185
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 189 bits (461), Expect = 4e-47
Identities = 92/186 (49%), Positives = 132/186 (70%), Gaps = 1/186 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K ALLSVSDKTG++ + L +G++++ +GGTA LR+A + V DVS++T PEM+GGR
Sbjct: 3 KRALLSVSDKTGIVEFARGLEALGVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGR 62
Query: 203 VKTLHPAVHAGILA-RLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP +H G+L R S E+ +++ +I ++ NLYPF TV++ +V + +A+EN
Sbjct: 63 VKTLHPRIHGGLLCLRESKEQMEEAAKEDISLIDLIAVNLYPFEITVSRENVELEEAIEN 122
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG TLLR+AAKN+ VTV+ DP+DY I+ E++ S S +TR LA+KAF HT+
Sbjct: 123 IDIGGPTLLRSAAKNYRSVTVLSDPSDYGRILKELRSS--GIISDKTRAELAVKAFRHTA 180
Query: 560 EYDLAI 577
+YD AI
Sbjct: 181 DYDAAI 186
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 188 bits (457), Expect = 1e-46
Identities = 97/185 (52%), Positives = 129/185 (69%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
ALLSVSDKTG++ + L + G++L+ +GGTA L L V++VSD T PEM+ GRVK
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVK 68
Query: 209 TLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENIDI 388
TLHP VH GIL R TD M++ E I +VV NLYPF TVAK D T+ADAVENIDI
Sbjct: 69 TLHPKVHGGILGR-RGTDDAIMQQHGIEGIDMVVVNLYPFAATVAKPDCTLADAVENIDI 127
Query: 389 GGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEYD 568
GG T++R+AAKNH V ++ + +D++ I+ EM Q ++ T ETR LA+KAF HT++YD
Sbjct: 128 GGPTMVRSAAKNHKDVAIVVNNHDFNAILAEMDQHQNSLT-FETRFDLAIKAFEHTAQYD 186
Query: 569 LAISD 583
I++
Sbjct: 187 SMIAN 191
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 186 bits (454), Expect = 3e-46
Identities = 95/185 (51%), Positives = 125/185 (67%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
ALLSVSDK G++ +ALS+ G++L+ +GGTA L +AGL V +VSD T PEM+ GRVK
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVK 69
Query: 209 TLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENIDI 388
TLHP VH GIL R D M + + I +VV NLYPF QTVA+ D ++ DAVENIDI
Sbjct: 70 TLHPKVHGGILGR-RGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDI 128
Query: 389 GGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEYD 568
GG T++R+AAKNH V ++ +DY II E+ + D + TR LA+KAF HT+ YD
Sbjct: 129 GGPTMVRSAAKNHKDVAIVVKSSDYPAIITEL-DNNDGSLTYPTRFNLAIKAFEHTAAYD 187
Query: 569 LAISD 583
I++
Sbjct: 188 SMIAN 192
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 186 bits (452), Expect = 4e-46
Identities = 100/190 (52%), Positives = 130/190 (68%), Gaps = 5/190 (2%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
AL+SVSDK G+L + L+ +G++L+ +GGTA LR+AGL V DVS+ T PEML GRVK
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVK 65
Query: 209 TLHPAVHAGILARLSNTDQED-MKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHP VH GILAR + D + + I +VV NLYPF TVA+ D T+ DA+ENID
Sbjct: 66 TLHPKVHGGILARRDLAEHMDTIAAHDISRIDLVVVNLYPFQATVARPDCTLEDAIENID 125
Query: 386 IGGVTLLRAAAKNHDR----VTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTH 553
IGG T++RAAAKNH V ++ DP DY I+ E+K + + S +TR LA+KAFTH
Sbjct: 126 IGGPTMVRAAAKNHGTEAGGVGIVTDPEDYAGIVAELK-ANANTLSYKTRFALAVKAFTH 184
Query: 554 TSEYDLAISD 583
T+ YD AIS+
Sbjct: 185 TARYDSAISN 194
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 182 bits (444), Expect = 4e-45
Identities = 95/185 (51%), Positives = 124/185 (67%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
ALLSVSDKTGL+ L +AL ++L+ +GGTAT +R AGL V DV+D+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVK 70
Query: 209 TLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENIDI 388
TLHP VH G+L R + D M + I +++ NLYPF Q AK D T+ADAV+ IDI
Sbjct: 71 TLHPMVHGGLLGR-AGIDDAVMAKHGIAPIDLLILNLYPFEQITAKKDCTLADAVDTIDI 129
Query: 389 GGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEYD 568
GG +LR+AAKN RV V P+ Y ++ E+ Q+ Q SAE R LA+ AF H ++YD
Sbjct: 130 GGPAMLRSAAKNFARVAVATSPDQYPDLLAEL-QAHHGQLSAEKRFALAVAAFNHVAQYD 188
Query: 569 LAISD 583
AIS+
Sbjct: 189 AAISN 193
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 182 bits (442), Expect = 7e-45
Identities = 92/186 (49%), Positives = 127/186 (68%), Gaps = 1/186 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
ALLSVSDKTGL+ ++L+ G++L+ +GGTA A+ +AGL V DVSD+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVK 70
Query: 209 TLHPAVHAGILARLSNTDQ-EDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHP VH G+LA N + E MK I ++V NLYPF TV +S +D +ENID
Sbjct: 71 TLHPKVHGGLLAIRGNDEHAEAMKTHGIAPIDLLVVNLYPFEATVERS-APFSDCIENID 129
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG ++RAA+KNH+ V V+ D NDYD ++ ++ + + T+ R+RLA KA+ T+ Y
Sbjct: 130 IGGPAMIRAASKNHEDVAVVVDVNDYDAVLEDLAR-HEGSTTLLLRRRLAAKAYARTAAY 188
Query: 566 DLAISD 583
D AIS+
Sbjct: 189 DAAISN 194
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 182 bits (442), Expect = 7e-45
Identities = 94/190 (49%), Positives = 126/190 (66%), Gaps = 6/190 (3%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
ALLSV +K+G++ K LS G L+ +GGTA +L + GL V VSD+T+ PEML GRVK
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVK 62
Query: 209 TLHPAVHAGILARLSNTD-QEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHP +H G+LAR Q D+ + N + IS+VV NLYPFV+TV+K T+ +A+ENID
Sbjct: 63 TLHPKIHGGLLARPELAHHQADLNKYNIKPISIVVVNLYPFVETVSKESTTLEEAIENID 122
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKD-----HQTSAETRQRLALKAFT 550
IGG TL+RA++KN V +I DP+DY I ++ S D + E R++LALKAF
Sbjct: 123 IGGHTLIRASSKNFQNVLIIVDPSDYKWIGERIQSSTDSTNVLSSITLEERKKLALKAFQ 182
Query: 551 HTSEYDLAIS 580
H YD A+S
Sbjct: 183 HGCSYDAAVS 192
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 180 bits (437), Expect = 3e-44
Identities = 88/188 (46%), Positives = 126/188 (67%), Gaps = 1/188 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+SVSDK G++ + L++ G +++ +GGT AL AG++ + + D+T PEM+ GR
Sbjct: 3 KRALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGR 62
Query: 203 VKTLHPAVHAGILARLS-NTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP +H G+LAR ++ + +I +VV NLYPF +T+ + DVT AVEN
Sbjct: 63 VKTLHPKIHGGLLARRDLDSHLQAANDHEIGLIDLVVVNLYPFKETILRPDVTYDLAVEN 122
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG ++LR+AAKNH VTV+ DP DY ++ E+ ++ +TS TRQRLA K F HT+
Sbjct: 123 IDIGGPSMLRSAAKNHASVTVVVDPADYPTVLGEI--AEQGETSYATRQRLAAKVFRHTA 180
Query: 560 EYDLAISD 583
YD I+D
Sbjct: 181 AYDALIAD 188
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 179 bits (436), Expect = 4e-44
Identities = 85/188 (45%), Positives = 127/188 (67%), Gaps = 1/188 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+SVSDKT L+ K L+E+G++++ +GGT L+ G+ V+ +S++T PE++ GR
Sbjct: 4 KRALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQENGVDVIGISEVTGFPEIMDGR 63
Query: 203 VKTLHPAVHAGILARLSNTDQ-EDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
+KTLHP +H G+LA N + + + I +VV NLYPF +T++K DVT +A+EN
Sbjct: 64 LKTLHPNIHGGLLAVRGNEEHMAQINEHGIQPIDLVVVNLYPFKETISKEDVTYEEAIEN 123
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG +LRAA+KNH VTVI DP DY ++N++K+ + S + ++ LA K F HT+
Sbjct: 124 IDIGGPGMLRAASKNHQDVTVIVDPADYSPVLNQIKE--EGSVSLQKKRELAAKVFRHTA 181
Query: 560 EYDLAISD 583
YD I+D
Sbjct: 182 AYDALIAD 189
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 177 bits (431), Expect = 2e-43
Identities = 94/186 (50%), Positives = 126/186 (67%), Gaps = 1/186 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
ALLSVSDKTGL ALS+ G++LV +GGT AL AGL+V +VS++T+ PEM+ GRVK
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVK 119
Query: 209 TLHPAVHAGILARLSNTD-QEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHPAVH G+LA N + Q + I ++V NLYPF +T+ K+ D VENID
Sbjct: 120 TLHPAVHGGLLAVRDNPEHQAALAAHGIGAIDLLVVNLYPFEETL-KAGKAYDDCVENID 178
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
+GG ++RAAAKNH V V+ D +DY I+ E+ + D +A TR+RLA KAF+ T+ Y
Sbjct: 179 VGGPAMIRAAAKNHADVAVVVDVSDYGAILAELAE-HDGNLTATTRRRLAQKAFSRTASY 237
Query: 566 DLAISD 583
D AI++
Sbjct: 238 DAAIAN 243
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 176 bits (428), Expect = 4e-43
Identities = 90/186 (48%), Positives = 122/186 (65%), Gaps = 1/186 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K A+LSVS+KTG++ KAL+++ +L +GGT L A + V VSD+T PE++ GR
Sbjct: 2 KKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGR 61
Query: 203 VKTLHPAVHAGILARLSNTDQ-EDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHPAVH GILA + ++ Q+ ++I +VV NLYPF QTVA DVT+ +A+EN
Sbjct: 62 VKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIEN 121
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG T+LRAAAKN+ VT I P DY ++ + ++ RQ L +K F HT+
Sbjct: 122 IDIGGPTMLRAAAKNYKHVTTIVHPADYHEVLTRL---RNDSLDESYRQSLMIKVFEHTA 178
Query: 560 EYDLAI 577
EYD AI
Sbjct: 179 EYDEAI 184
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 175 bits (425), Expect = 8e-43
Identities = 92/189 (48%), Positives = 126/189 (66%), Gaps = 2/189 (1%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKAL-SEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGG 199
+LALLSVSDK+G++ L + L +E L+ SGGTA L+ AG+ V VSD T APE+LGG
Sbjct: 3 RLALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGG 62
Query: 200 RVKTLHPAVHAGILARLS-NTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVE 376
RVKTLHP +H GILAR +DQ D++ + + +VV NLYPF QT+AK VTVA+AVE
Sbjct: 63 RVKTLHPRIHGGILARRDLPSDQADLEANDIRPLDLVVVNLYPFEQTIAKPGVTVAEAVE 122
Query: 377 NIDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHT 556
IDIGG ++RA AKN TV+ +PN Y+ + +++ + RQ+ A +AF T
Sbjct: 123 QIDIGGPAMIRATAKNFAHTTVLTNPNQYEAYLQALQE--QGEIPLALRQQFAGEAFALT 180
Query: 557 SEYDLAISD 583
+ YD AI++
Sbjct: 181 NAYDQAIAN 189
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 174 bits (424), Expect = 1e-42
Identities = 96/188 (51%), Positives = 119/188 (63%), Gaps = 2/188 (1%)
Frame = +2
Query: 26 LALLSVSDKTGLLILGKAL-SEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
LALLSVSDKTGL+ L +AL E G QL+ SGGTA AL AG+ V VS+ T APE+LGGR
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGR 68
Query: 203 VKTLHPAVHAGILARLSNT-DQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP +H GILARL D+ D++ I +VV N YPF QTVA++ V++ +A E
Sbjct: 69 VKTLHPRIHGGILARLERREDRADLEALGIPPIQLVVVNFYPFEQTVARAGVSLEEAFEQ 128
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG TL RAAAKN+ VTV+ DP+ Y + + R + A +AF
Sbjct: 129 IDIGGPTLARAAAKNYPHVTVLTDPSQYPQYLQLLSSPSSEAERLAFRFQCARRAFEQVL 188
Query: 560 EYDLAISD 583
YD AI D
Sbjct: 189 AYDRAIVD 196
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 173 bits (421), Expect = 3e-42
Identities = 90/192 (46%), Positives = 122/192 (63%), Gaps = 2/192 (1%)
Frame = +2
Query: 14 SNGKLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEML 193
S K AL+S+SDKT L LG L E+G +V +GGT++AL AG+SV V ++T+ PEML
Sbjct: 86 SGRKQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRFPEML 145
Query: 194 GGRVKTLHPAVHAGILARLSNT-DQEDMKRQNFEMISVVVCNLYPFVQTVAKSD-VTVAD 367
GRVKTLHP+VH GILAR E +++ VVV NLYPF V+ S ++ D
Sbjct: 146 DGRVKTLHPSVHGGILARRDQEHHMEALEKHEIGTFDVVVVNLYPFYAKVSSSSGISFED 205
Query: 368 AVENIDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAF 547
+ENIDIGG ++RAAAKNH V V+ D DY ++ ++ D Q + R++LA KAF
Sbjct: 206 GIENIDIGGPAMIRAAAKNHRDVLVVVDSEDYPALLEFLRGDNDDQ---QFRRKLAWKAF 262
Query: 548 THTSEYDLAISD 583
H + YD A+S+
Sbjct: 263 QHVASYDSAVSE 274
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 173 bits (420), Expect = 3e-42
Identities = 97/189 (51%), Positives = 120/189 (63%), Gaps = 2/189 (1%)
Frame = +2
Query: 17 NGKLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLG 196
N K AL+SVSDK GL+ K L + G++++ +GGTA L +AG+ V VSD+T PE+LG
Sbjct: 2 NIKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILG 61
Query: 197 GRVKTLHPAVHAGILARLSNTDQEDMKRQNF-EMISVVVCNLYPFVQTVAKS-DVTVADA 370
GRVKTLHP + GILA L + R NF E I +VV NLYPF + K+ D V
Sbjct: 62 GRVKTLHPKIFGGILADLGDKSHVKDLRDNFIEPIDLVVVNLYPFDEVQKKTRDEDV--L 119
Query: 371 VENIDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFT 550
+ENIDIGGV LLRAAAKNH V V+CDP DYD +I + D Q R+ ALKAF
Sbjct: 120 IENIDIGGVALLRAAAKNHRNVVVVCDPADYDKVIKSIDLCGDVQ--LHDRRMFALKAFY 177
Query: 551 HTSEYDLAI 577
HT +YD I
Sbjct: 178 HTMKYDATI 186
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 168 bits (408), Expect = 1e-40
Identities = 83/188 (44%), Positives = 118/188 (62%), Gaps = 1/188 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+SVSDKT ++ K L E G +++ +GGT ++ AG+ V V ++T PEML GR
Sbjct: 3 KRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGR 62
Query: 203 VKTLHPAVHAGILARLSNTDQ-EDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP +H G+L + SN + M+ I +V NLYPF +TV K DV+ D +EN
Sbjct: 63 VKTLHPMIHGGLLGKRSNHEHLSQMEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDIIEN 122
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG ++LR+AAKN + V V+ P DY+ ++ + D + E RQ+LA K F HT+
Sbjct: 123 IDIGGPSMLRSAAKNFEDVLVVTGPTDYNRVLAAITSETD---TYEFRQQLAAKVFRHTA 179
Query: 560 EYDLAISD 583
YD I++
Sbjct: 180 SYDAMIAN 187
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 167 bits (407), Expect = 1e-40
Identities = 94/186 (50%), Positives = 119/186 (63%), Gaps = 2/186 (1%)
Frame = +2
Query: 26 LALLSVSDKTGLLILGKAL-SEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
LALLSVSDKTGL+ L ++L E G QL+ SGGTA AL AG+ V VS T APE+LGGR
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGR 76
Query: 203 VKTLHPAVHAGILARLS-NTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP +H GILARL + D+ D++ I +VV N YPF QTVA++ V++ +A E
Sbjct: 77 VKTLHPRIHGGILARLECSEDRADLEALGIPPIQLVVVNFYPFEQTVAQAGVSLEEAFEQ 136
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG TL RAAAKN+ VTV+ DP+ Y + + + R + A +AF
Sbjct: 137 IDIGGPTLARAAAKNYPYVTVLTDPSQYPRYLQLLSGAYGETERLAFRFQCARRAFEQVL 196
Query: 560 EYDLAI 577
YD AI
Sbjct: 197 AYDRAI 202
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 167 bits (407), Expect = 1e-40
Identities = 89/186 (47%), Positives = 117/186 (62%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+SVSDKTG++ L + G +L+ +GGT L AG+ V VSD+T PEML GR
Sbjct: 3 KRALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGR 62
Query: 203 VKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENI 382
VKTLHPA+H GILAR + Q+ I +V NLYPF +TVA+ + +ENI
Sbjct: 63 VKTLHPAIHGGILARREAGHLGQLAAQDIGTIDLVCVNLYPFRETVARG-APDPEVIENI 121
Query: 383 DIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSE 562
DIGG ++R+AAKNHD V V+ DP DY + + + + S R+RLA KA+ HTSE
Sbjct: 122 DIGGPAMIRSAAKNHDAVLVLVDPADYALALQD-------EVSPAERRRLAAKAYRHTSE 174
Query: 563 YDLAIS 580
YD AI+
Sbjct: 175 YDAAIT 180
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 167 bits (406), Expect = 2e-40
Identities = 85/184 (46%), Positives = 122/184 (66%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
AL+SVSDK+ L +L + L ++++ +GGT AL G++V+ VS+ T APE+L GRVK
Sbjct: 17 ALVSVSDKSKLDVLAEILIAHKVEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVK 76
Query: 209 TLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENIDI 388
TLHP +H GILA + Q +++ + I +V+ NLYPF +T+AK + ADA+ENIDI
Sbjct: 77 TLHPKIHGGILALPTEAHQRELELHDIAPIDLVIVNLYPFRETIAKPGCSFADAIENIDI 136
Query: 389 GGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEYD 568
GG T++RAAAKN +RV VI DP DY ++E+ + R+ +A KAF HT+ YD
Sbjct: 137 GGPTMVRAAAKNWNRVAVIVDPEDYS-SLSEVLGETEGTLPESFRRNMARKAFAHTAAYD 195
Query: 569 LAIS 580
AI+
Sbjct: 196 AAIA 199
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 166 bits (404), Expect = 3e-40
Identities = 89/185 (48%), Positives = 117/185 (63%), Gaps = 1/185 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
AL+SV DKTGL L K L E G+++V +G TA + AG+ V +V ++T +PEML GRVK
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVK 73
Query: 209 TLHPAVHAGILA-RLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHP VH GILA R E + E +VV NLYPFV+TV KS D VE ID
Sbjct: 74 TLHPRVHGGILADRRVPAHMETLAGMEIEAFDLVVVNLYPFVETV-KSGAAQDDVVEQID 132
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG ++R+AAKNH V ++ DPN Y ++ + + + +TRQRLA KAF HT+ Y
Sbjct: 133 IGGPAMVRSAAKNHAAVAIVTDPNFYGDVV---RAAAEGGFDLKTRQRLAAKAFAHTASY 189
Query: 566 DLAIS 580
D A++
Sbjct: 190 DTAVA 194
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 166 bits (404), Expect = 3e-40
Identities = 91/185 (49%), Positives = 123/185 (66%), Gaps = 1/185 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
A++SV K G+ L KAL E+G ++V +GGTA LR G+SV +VS+IT PE+L GRVK
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVK 62
Query: 209 TLHPAVHAGILAR-LSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHP VH GIL R D+E++++ + I VVV NLYPF + + K +T D +E ID
Sbjct: 63 TLHPVVHGGILFRDWVEKDKEEIEKHGIKPIDVVVVNLYPFEEKL-KEGLTDKDLMEFID 121
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG TL+RAAAKN RV ++ DP DYD +I ++K+ + + R LA KAF+HT+ Y
Sbjct: 122 IGGPTLIRAAAKNFFRVVILVDPEDYDWVIEKLKKG---NLTLQDRAYLAWKAFSHTAYY 178
Query: 566 DLAIS 580
D IS
Sbjct: 179 DGVIS 183
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 166 bits (403), Expect = 4e-40
Identities = 86/187 (45%), Positives = 121/187 (64%), Gaps = 1/187 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+SVSDK+GL L +AL+ +++V +G TA +R + V DVS++T E+L GR
Sbjct: 8 KRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGR 67
Query: 203 VKTLHPAVHAGILA-RLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP +HA ILA S + +++ + +VV NLYPF + S+ +D +E
Sbjct: 68 VKTLHPKIHAPILADTTSQMHRAQLQQLGVDAFDLVVVNLYPFFEISKNSEAEFSDVIEQ 127
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG L+RAAAKNH RV VI DP+DY +IN +++ + R +LA+KA++HTS
Sbjct: 128 IDIGGSALIRAAAKNHTRVVVIVDPSDYIHVINSLERG----APSRLRHQLAIKAYSHTS 183
Query: 560 EYDLAIS 580
EYDL IS
Sbjct: 184 EYDLHIS 190
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 166 bits (403), Expect = 4e-40
Identities = 84/187 (44%), Positives = 123/187 (65%), Gaps = 1/187 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+SVSDK+GL+ K L++ G++++ +GGT L++ G++ + + D T PE+L GR
Sbjct: 5 KRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGR 64
Query: 203 VKTLHPAVHAGILARLSN-TDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP VH G+L +SN ++ M+ I +VV NLYPF++TV+K +V + +A+EN
Sbjct: 65 VKTLHPKVHGGLLGVISNPAHKQKMEELKIPKIDLVVVNLYPFLKTVSKPEVQLEEAIEN 124
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG +++R+AAKN+ V+ DPNDY I N + S S E KAF+HT+
Sbjct: 125 IDIGGPSMIRSAAKNYKHTLVLTDPNDYKKIQNLISSS---GISEEISASYMRKAFSHTA 181
Query: 560 EYDLAIS 580
YD AIS
Sbjct: 182 MYDAAIS 188
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 165 bits (402), Expect = 5e-40
Identities = 87/186 (46%), Positives = 121/186 (65%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+S +DK GL+ L G++++ +GGTA L+ L V+DV T PE++ GR
Sbjct: 12 KRALISTADKIGLIEFISQLVTCGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGR 71
Query: 203 VKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENI 382
VKTLHP +HAG+LAR D++ + + + I ++V NLYPFVQTV+ S+ ++ AVE I
Sbjct: 72 VKTLHPKIHAGLLAR-RGIDEKTLDQHAIKPIDLLVVNLYPFVQTVSASNCSLEKAVEQI 130
Query: 383 DIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSE 562
DIGG ++LRAAAKN VTV+ DP DY I+ E+K + T+ TR+RLA K F H S
Sbjct: 131 DIGGPSMLRAAAKNFAAVTVVVDPEDYSRILEEIK-THHGSTTLSTRKRLAQKTFEHLSY 189
Query: 563 YDLAIS 580
YD I+
Sbjct: 190 YDAHIA 195
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 165 bits (401), Expect = 7e-40
Identities = 92/185 (49%), Positives = 121/185 (65%), Gaps = 1/185 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
AL+SV DKTG+L L K L G +++ SGGT T L+NAG+ ++VS++T E+LGGRVK
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVK 62
Query: 209 TLHPAVHAGILARLS-NTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHPA+H GIL R D E++K + E I +VV NLYPF + + K + VE ID
Sbjct: 63 TLHPAIHGGILFREDVEKDLEEIKENSIEPIDIVVVNLYPFEKKM-KELKDIDALVEFID 121
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG TL+RAAAKNH RV+V+ D DY I ++K + S + R+ LALKAF TS Y
Sbjct: 122 IGGPTLVRAAAKNHKRVSVLTDIEDYGWFIEKLKM---NAVSQQDRKYLALKAFWLTSYY 178
Query: 566 DLAIS 580
D I+
Sbjct: 179 DAVIA 183
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 164 bits (399), Expect = 1e-39
Identities = 88/186 (47%), Positives = 122/186 (65%)
Frame = +2
Query: 26 LALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRV 205
LALLSV DKTG+L L +AL + ++ SGGTA ALR AG+ DVS+ T+ PEM+ GRV
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRV 62
Query: 206 KTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
KTLHP VH G+L R D + MK E I ++ NLYPF + ++K ++ + + +E ID
Sbjct: 63 KTLHPKVHGGLLGR-RGIDDDVMKAHFIEPIDILCVNLYPF-EEMSKKNLPLEELIEFID 120
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG ++RAA+KN+ V V+ DP+DY + I +K ++E + RLA KAFT T+ Y
Sbjct: 121 IGGPAMIRAASKNYKDVAVLTDPSDYPMAIEAIKTG---GFTSEQKLRLATKAFTRTAAY 177
Query: 566 DLAISD 583
D AIS+
Sbjct: 178 DAAISN 183
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 163 bits (396), Expect = 3e-39
Identities = 83/181 (45%), Positives = 119/181 (65%), Gaps = 1/181 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
AL+SVSDKTG++ L +++V +GGTA LR AG+ V DVSD+T PEM+ GRVK
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVK 74
Query: 209 TLHPAVHAGIL-ARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHP +H G+L R S + + M+ E I +VV +LYPF +T+ + V++A+A+E ID
Sbjct: 75 TLHPKIHGGLLGVRDSPSHESSMREHGIEPIDMVVIDLYPFERTIKGAAVSLAEAIEQID 134
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG ++R+AAKN V VI + ++Y I E++ + D S TR+RLA AF T++Y
Sbjct: 135 IGGPAMIRSAAKNFHSVAVITNTSEYGPIAEELR-AHDCSLSLHTRRRLAEIAFQRTAQY 193
Query: 566 D 568
D
Sbjct: 194 D 194
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 161 bits (391), Expect = 1e-38
Identities = 81/186 (43%), Positives = 119/186 (63%), Gaps = 1/186 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
ALLSVSDK G++ GK L +G +++ +GGT L+ G+ V++VSD TK+PE+ GRVK
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVK 62
Query: 209 TLHPAVHAGILARLSNTDQEDMKRQNFEM-ISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHP +H GIL + S+ + ++N + I +V NLYPF +T SD + +ENID
Sbjct: 63 TLHPKIHGGILHKRSDENHIKQAKENEILGIDLVCVNLYPFKKTTIMSD-DFDEIIENID 121
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG ++R+AAKN+ V V+CDP DY+ +I +K+ Q R L +KA+ HT+ Y
Sbjct: 122 IGGPAMIRSAAKNYKDVMVLCDPLDYEKVIETLKKG---QNDENFRLNLMIKAYEHTANY 178
Query: 566 DLAISD 583
D I++
Sbjct: 179 DAYIAN 184
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 157 bits (380), Expect = 2e-37
Identities = 79/188 (42%), Positives = 127/188 (67%), Gaps = 1/188 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+SVSDK L L + L++ ++L+ SGGT ++ +VS+ T +PE+LGGR
Sbjct: 12 KKALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGR 71
Query: 203 VKTLHPAVHAGILA-RLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP +HAGIL+ R + +++K ++ I +V+ N YPF +T+ ++ + +EN
Sbjct: 72 VKTLHPKIHAGILSKRNDKSHTKELKANQYDEIDLVIVNFYPFEKTLDQT-TNHSKIIEN 130
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
ID+GG T++RAAAKN++ VTVI + Y+ +INE++ +K TS E R++++L+AF+ T+
Sbjct: 131 IDVGGPTMVRAAAKNYNDVTVITSSDQYETLINELENNKG-STSIEFREKMSLEAFSETA 189
Query: 560 EYDLAISD 583
YD IS+
Sbjct: 190 YYDAVISN 197
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 155 bits (376), Expect = 7e-37
Identities = 85/187 (45%), Positives = 117/187 (62%), Gaps = 1/187 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+SV DKTGL L +AL E G+++V +G TA + AG++V V D+T PE+L GR
Sbjct: 17 KRALISVYDKTGLEDLARALGEAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGR 76
Query: 203 VKTLHPAVHAGILA-RLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP +H+GILA + +E + + + +VVCNLYPF TVA S + + VE
Sbjct: 77 VKTLHPFIHSGILADQRKAAHREQIAQLGIQAFDLVVCNLYPFQDTVA-SGASFDECVEQ 135
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG +++RAAAKNH V V+ P Y + + + E R+ LA +AF HT+
Sbjct: 136 IDIGGPSMVRAAAKNHPSVAVVTSPERYADVAEAV---AGEGFTLEQRRVLAAEAFAHTA 192
Query: 560 EYDLAIS 580
YDLAI+
Sbjct: 193 TYDLAIA 199
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 155 bits (376), Expect = 7e-37
Identities = 86/188 (45%), Positives = 120/188 (63%), Gaps = 1/188 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+SV DK G+L L K L + ++++ SGGT L+ + V ++S+IT PEML GR
Sbjct: 3 KRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGR 62
Query: 203 VKTLHPAVHAGILARLSNTD-QEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP VHAGILA N + + ++ + I VV NLYPF + V + D++ + VE
Sbjct: 63 VKTLHPLVHAGILAIRDNKEHMKTLEEREINTIDYVVVNLYPFFEKV-REDLSFEEKVEF 121
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG T+LRAAAKN V V+ D DY+ ++NE+K+ ++ S + R+ LA K F S
Sbjct: 122 IDIGGPTMLRAAAKNFKDVVVLSDKKDYEKVMNEIKE--NNCVSFKLRKTLAGKVFNLMS 179
Query: 560 EYDLAISD 583
YD AIS+
Sbjct: 180 AYDAAISN 187
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 153 bits (371), Expect = 3e-36
Identities = 79/186 (42%), Positives = 115/186 (61%), Gaps = 1/186 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
AL+SV K G+ +L +A + G ++V +G TA L G+ V +VSD+T PE L GRVK
Sbjct: 11 ALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVK 70
Query: 209 TLHPAVHAGILARLSNTDQ-EDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHP +HAGILA ++N + + ++ + +VV NLYPF TV +S AD +E ID
Sbjct: 71 TLHPYIHAGILADMTNPEHAKQLEEFGIKPFDLVVVNLYPFADTV-RSGANEADTIEKID 129
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG +++R AAKNH V ++ DP DY ++ + + S + R+ LA KAF HT+ Y
Sbjct: 130 IGGPSMVRGAAKNHATVAIVTDPADYALVASRVADGTGF--SLDERKWLAAKAFAHTAAY 187
Query: 566 DLAISD 583
D I++
Sbjct: 188 DATINE 193
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 148 bits (359), Expect = 8e-35
Identities = 80/185 (43%), Positives = 112/185 (60%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
AL+SV DK+ LL K+LS +G++L+ + GTA L NAGL+V +SD T PE++ G+VK
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVK 69
Query: 209 TLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENIDI 388
TLH + AGIL+R N D+ + + + I +V+ N YPF + +E IDI
Sbjct: 70 TLHHKICAGILSR-KNLDESIIHKYGIQPIDMVIVNFYPFHLILQNKQHDSEKILEYIDI 128
Query: 389 GGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEYD 568
GG ++RAAAKN+ +I D NDYD I+NE+ + S TR LA KAF + +YD
Sbjct: 129 GGPNMVRAAAKNYKNTVIIVDNNDYDNILNEI-NTLHGSISLNTRLNLAAKAFKYIKQYD 187
Query: 569 LAISD 583
ISD
Sbjct: 188 TMISD 192
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 148 bits (358), Expect = 1e-34
Identities = 79/182 (43%), Positives = 114/182 (62%)
Frame = +2
Query: 32 LLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVKT 211
L+SVSD +GL L L + + + GT L ++G+ +SDIT ++L GRVKT
Sbjct: 4 LVSVSDTSGLTDL---LRHLNGDVYATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKT 60
Query: 212 LHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENIDIG 391
LHPAV +GIL+R + D+KR N+ +V+CNLY F + KS + D +ENIDIG
Sbjct: 61 LHPAVFSGILSRRDEQSEADLKRYNYFDFDIVICNLYNFESYIDKS---IEDMIENIDIG 117
Query: 392 GVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEYDL 571
G++L+RAAAKN+ VTV P DY++II ++ +D + S TR+ LAL+AF + YD+
Sbjct: 118 GLSLIRAAAKNYQHVTVASSPEDYNIIIKDL---RDGEISLRTRETLALRAFARAAYYDM 174
Query: 572 AI 577
I
Sbjct: 175 II 176
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 147 bits (356), Expect = 2e-34
Identities = 81/187 (43%), Positives = 112/187 (59%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K ALLSV DKTG++ L +AL + ++ SGGT TAL AG+ +VS T PEM+ GR
Sbjct: 32 KWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGR 91
Query: 203 VKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENI 382
VKTLHP VH G+L R D M + I ++V NLYPF + +++ + + +E I
Sbjct: 92 VKTLHPKVHGGLLGR-RQIDDAIMAKYGINRIGLLVVNLYPF-ERMSRESLPLEKLIEYI 149
Query: 383 DIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSE 562
D+GG ++RAAAKN V V+ DP+DY ++ + S + S E R A KAF T+
Sbjct: 150 DVGGPAMIRAAAKNFKDVAVVVDPSDYPEVVKTL--SSNVGFSHEQRLIFAKKAFARTAA 207
Query: 563 YDLAISD 583
YD AIS+
Sbjct: 208 YDAAISN 214
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 146 bits (353), Expect = 4e-34
Identities = 79/186 (42%), Positives = 109/186 (58%), Gaps = 1/186 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
ALLSV+DK+GL+ L++ G++LV +GGT L AGL V VS +T PE++GGRVK
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVK 121
Query: 209 TLHPAVHAGILARLSNTDQ-EDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHP +H GILA N + +K ++ NLY F A+ + + AVE +D
Sbjct: 122 TLHPHIHGGILADKDNPEHLATLKELGIRTFDLICVNLYNFADAAARG-LDLRGAVEEVD 180
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG +LRA AKN + V+ DP DY + EM+ + D + RQ +A+K F TS Y
Sbjct: 181 IGGPCMLRATAKNFHSMLVLPDPADYQAAMQEMRDN-DMRVGLAMRQAMAVKTFRATSAY 239
Query: 566 DLAISD 583
D I+D
Sbjct: 240 DGMIAD 245
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 140 bits (340), Expect = 2e-32
Identities = 81/185 (43%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
ALLSVSDKTGLL L K L+ ++L+ SGGTA AL AGL V V ++ E GR+K
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMK 66
Query: 209 TLHPAVHAGIL-ARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
T+ + + +L R D E I +VV NLYPF T+ K + +ENID
Sbjct: 67 TISFEIASSLLFRRQDENDVRQAAELGIEPIDLVVVNLYPFHATLQK-QAGFEECIENID 125
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG TLLRA AKN VTV+CDP+ Y + E + T+ E RQ+ A +T T+ Y
Sbjct: 126 IGGPTLLRAGAKNFHSVTVLCDPSQYSEFLKEF-NGNNGSTTWEFRQKCAAAVYTMTAFY 184
Query: 566 DLAIS 580
D+AI+
Sbjct: 185 DMAIA 189
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 136 bits (330), Expect = 3e-31
Identities = 72/185 (38%), Positives = 110/185 (59%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
+ AL+SVSDKTG+ L K L + ++L+ + GT L G+ VS+ PE++ GR
Sbjct: 9 RCALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGR 68
Query: 203 VKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENI 382
VKTLHP +H GIL+ N ++ K N + I +V+ N YPF + V K ++ + + ++NI
Sbjct: 69 VKTLHPKIHGGILSNNKNINEN--KNLNIKKIDMVITNFYPFKKKVKKENIKIENIIDNI 126
Query: 383 DIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSE 562
DIGGV L R+AAKN+ VTV+ + N Y + +EM ++ S +TR + AF ++
Sbjct: 127 DIGGVALARSAAKNYKYVTVVVNINQYSKLSSEMDKNSG-SVSFKTRFYFSTLAFQYSYS 185
Query: 563 YDLAI 577
YD I
Sbjct: 186 YDKEI 190
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 133 bits (322), Expect = 3e-30
Identities = 86/192 (44%), Positives = 110/192 (57%), Gaps = 8/192 (4%)
Frame = +2
Query: 32 LLSVSDKTGLLILGKALSEMG--LQLVGSGGTATALR----NAGLSVL-DVSDITKAPEM 190
L+SVSDKTGL L + + + +GGT + +A SVL VSD T PE
Sbjct: 19 LISVSDKTGLEEFVTRLVRINPDVHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPET 78
Query: 191 LGGRVKTLHPAVHAGILARLSNTDQ-EDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVAD 367
GG VKTL ++ G+L N DMKR I +VV NLYPF QTVA+ DVT
Sbjct: 79 QGGLVKTLDFKIYLGLLTETYNESHARDMKRTGAVAIDMVVVNLYPFSQTVARPDVTPEQ 138
Query: 368 AVENIDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAF 547
A NIDIGG ++RA+AKN RV + DP DY+ + +EM + + S +TR LA KAF
Sbjct: 139 ARGNIDIGGPCMVRASAKNFLRVASVVDPADYNTVADEM-EHRQGALSLDTRFELAQKAF 197
Query: 548 THTSEYDLAISD 583
HT+ YD AI+D
Sbjct: 198 DHTAAYDRAIAD 209
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 132 bits (318), Expect = 8e-30
Identities = 74/188 (39%), Positives = 112/188 (59%), Gaps = 1/188 (0%)
Frame = +2
Query: 17 NGKLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLG 196
N K A++SV DKT L L L G++++ + GT L+ G+ + ++D PE+LG
Sbjct: 2 NIKRAIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILG 61
Query: 197 GRVKTLHPAVHAGILARLSN-TDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAV 373
GRVK++ P + GILA+ ++ +EDM N + I +VV N +P + +AK +
Sbjct: 62 GRVKSIDPKLAGGILAKSNDKKHEEDMINYNIKRIDMVVGN-FPTFEEIAKKTKNEETLL 120
Query: 374 ENIDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTH 553
ENIDIGG +LLRAAAKN+ V + DP DY +I+ ++ D + R++LALK F
Sbjct: 121 ENIDIGGYSLLRAAAKNYKDVVALADPKDYQTVIDNLEDCGD--VPLQLRRKLALKVFFS 178
Query: 554 TSEYDLAI 577
TS+YD +I
Sbjct: 179 TSKYDASI 186
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 132 bits (318), Expect = 8e-30
Identities = 66/182 (36%), Positives = 111/182 (60%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K L+SVSD + ++ K+L ++L + GTA L+ + D+++ T PE++ GR
Sbjct: 8 KNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGR 67
Query: 203 VKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENI 382
+KTLH ++A ILA+ + D++ +++ N ++ +VV N YPF + +++ + D +E+I
Sbjct: 68 IKTLHHKIYASILAQPKH-DKKTIEKYNIILMDIVVINFYPFEEASNNTNLHLNDIIEHI 126
Query: 383 DIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSE 562
DIGG ++RAAAKN+ V V+ PN Y I+NEM + ++ S T+ + A AF HT
Sbjct: 127 DIGGPAIVRAAAKNYKNVLVVTQPNLYQSIVNEMNLN-NNIISETTKLKFATIAFKHTMN 185
Query: 563 YD 568
YD
Sbjct: 186 YD 187
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 128 bits (309), Expect = 1e-28
Identities = 73/184 (39%), Positives = 108/184 (58%), Gaps = 1/184 (0%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVK 208
AL+SV K GL + L+ G++ V +GGT + + G + V D+T+ P MLGGRVK
Sbjct: 11 ALISVYHKEGLAEILAELNRQGVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVK 70
Query: 209 TLHPAVHAGILARLSN-TDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
TLHP + GILAR + +D ++ +I +V+ +LYPF TVA S + D +E ID
Sbjct: 71 TLHPMIFGGILARRGHESDVREVGEYGLPLIDLVIVDLYPFEATVA-SGASEEDIIEKID 129
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
IGG++L+R AAKN + V +I Y + +K+ + +TS R+ A +AF +S Y
Sbjct: 130 IGGISLIRGAAKNFEDVVIISSRAQYAGFYSLLKE-QGARTSLAERRHYAREAFAVSSAY 188
Query: 566 DLAI 577
D AI
Sbjct: 189 DSAI 192
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 127 bits (307), Expect = 2e-28
Identities = 73/186 (39%), Positives = 108/186 (58%), Gaps = 1/186 (0%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K AL+SV K GL + L E G++ + +GGT + + G V D+T P +LGGR
Sbjct: 8 KTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGR 67
Query: 203 VKTLHPAVHAGILARLS-NTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVEN 379
VKTLHP + GIL R D + +++ I +V+ +LYPF TVA S + AD +E
Sbjct: 68 VKTLHPKIFGGILCRRDLEQDIQQIEKYEIPEIDLVIVDLYPFEATVA-SGASEADIIEK 126
Query: 380 IDIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTS 559
IDIGG++L+RAAAKN++ V ++ Y ++ +M +S E R+ +A +AF +S
Sbjct: 127 IDIGGISLIRAAAKNYNDVIIVASQAQYKPLL-DMLMEHGATSSLEERRWMAKEAFAVSS 185
Query: 560 EYDLAI 577
YD AI
Sbjct: 186 HYDSAI 191
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 105 bits (252), Expect = 8e-22
Identities = 67/185 (36%), Positives = 98/185 (52%)
Frame = +2
Query: 26 LALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRV 205
LA+L+VSDK + L L +G +V + GT LR+ G++V VSD+ P +LGGRV
Sbjct: 2 LAVLAVSDKRNIEELATGLLGLGWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRV 61
Query: 206 KTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
KTL ++ GILAR D+ +++R + +V CN Y + E ID
Sbjct: 62 KTLTVSLMGGILARDEPADRAEVERHGLTRVHLVCCNYYRLPD--PQPAQPFERFRELID 119
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEY 565
+GG +LRAAAKN V + DP+DY + +K D R LA KAF ++ Y
Sbjct: 120 VGGPAMLRAAAKNCAHVVPLSDPDDYAGV---LKALADGGVDRRQRLDLARKAFAVSAAY 176
Query: 566 DLAIS 580
D +++
Sbjct: 177 DTSVA 181
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 85.4 bits (202), Expect = 9e-16
Identities = 46/107 (42%), Positives = 59/107 (55%), Gaps = 1/107 (0%)
Frame = +2
Query: 11 ASNGKLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEM 190
AS K AL+S+S+K L LG +L +G ++V GGT AL NA +S V +T P++
Sbjct: 18 ASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKI 77
Query: 191 LGGRVKTLHPAVHAGILARLSNT-DQEDMKRQNFEMISVVVCNLYPF 328
L G VKTLHP + GIL R E + VVV NLYPF
Sbjct: 78 LDGHVKTLHPNIQGGILPRRDQKHHMEALNEHGIGTFDVVVVNLYPF 124
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 74.1 bits (174), Expect = 2e-12
Identities = 37/79 (46%), Positives = 49/79 (62%)
Frame = +2
Query: 11 ASNGKLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEM 190
AS K AL+S+S+K L LG +L +G ++V GGT AL NA +S V +T P++
Sbjct: 18 ASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKI 77
Query: 191 LGGRVKTLHPAVHAGILAR 247
L G VKTLHP + GIL R
Sbjct: 78 LDGHVKTLHPNIQGGILPR 96
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 70.1 bits (164), Expect = 4e-11
Identities = 66/182 (36%), Positives = 84/182 (46%)
Frame = +2
Query: 23 KLALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGR 202
K L+S+ +K L + + L E G ++ S GTA L++ G+ DVS IT +LGG
Sbjct: 2 KRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGL 61
Query: 203 VKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENI 382
VKTLHP + AGIL D VV +LYP +I
Sbjct: 62 VKTLHPEIFAGILGPEPRWD-------------VVFVDLYP---------------PPDI 93
Query: 383 DIGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSE 562
DIGGV LLRAAAKN +V D + I E+ ETR+ LA F TS
Sbjct: 94 DIGGVALLRAAAKNWKKVKPAFDMETLKLAI-EIDDE-------ETRKYLAGMTFAFTSV 145
Query: 563 YD 568
YD
Sbjct: 146 YD 147
>UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n=1;
Archaeoglobus fulgidus|Rep: Inosine monophosphate
cyclohydrolase - Archaeoglobus fulgidus
Length = 157
Score = 59.3 bits (137), Expect = 7e-08
Identities = 59/184 (32%), Positives = 90/184 (48%)
Frame = +2
Query: 32 LLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVKT 211
L+S S K G+ L K L+EMG +++ + GTA L+ G++ L +S+IT E +KT
Sbjct: 4 LISSSVKEGIECLAKRLAEMGYEILATEGTADYLQEKGVNALKLSEITGIAE--SKSIKT 61
Query: 212 LHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENIDIG 391
LHP ++ I + E+ +VVV P+ ++ ENIDIG
Sbjct: 62 LHPKIYEMIFSG--------------EIKAVVV---IPY-------NLRENPCRENIDIG 97
Query: 392 GVTLLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQTSAETRQRLALKAFTHTSEYDL 571
G++LLRAAAK V D + ++ E+ + K +AE F TSEYD
Sbjct: 98 GISLLRAAAK--AGVPAAYDLKSFQKLV-EVLEGKKRYNAAE--------VFRFTSEYDR 146
Query: 572 AISD 583
I++
Sbjct: 147 TIAE 150
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 52.8 bits (121), Expect = 6e-06
Identities = 39/150 (26%), Positives = 67/150 (44%), Gaps = 1/150 (0%)
Frame = -2
Query: 574 GEVILGGVCKSLEGQSLSGFC*GLVIFALFHFINNHIIVIRITDNSDSIVILSRSPEESH 395
G V+ GV L GQ+ G +FH + +H ++ + D+ D V+L E
Sbjct: 358 GAVVGCGVLIHLHGQTEIGLARHAAA-GVFHLVQDHCVIGVVNDDGDVAVVLGCGAEHGR 416
Query: 394 TTYIYIFNSVRNSDV*FSNCLNERIKVANDHAYHFKVLTLHILLI-GVRKSSQYAGVNSR 218
I + + + + V F + ER++V + H + LH+ + V ++ A VN R
Sbjct: 417 AADIDVLDGILHGAVLFRDGRLERVEVYHHHVDGLDAVLLHLGYVRRVLAHAEDAAVNLR 476
Query: 217 M*GLHTASKHFRRFSNI*DVKDRKSCVPQR 128
+ GL A +H + DV D S + Q+
Sbjct: 477 VQGLDPAVQHLGETGELGDVLDGDSRLTQK 506
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 52.4 bits (120), Expect = 8e-06
Identities = 27/64 (42%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +2
Query: 188 MLGGRVKTLHPAVHAGILARLSNT-DQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVA 364
ML G VKTLHP +H GILAR E + VVV NLYPF V+ +
Sbjct: 1 MLDGHVKTLHPNIHGGILARRDQKHHMEALNEHGIGTFDVVVVNLYPFYDKVSLGGIEFE 60
Query: 365 DAVE 376
D +E
Sbjct: 61 DEIE 64
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 41.1 bits (92), Expect = 0.019
Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 3/150 (2%)
Frame = -2
Query: 487 FHFINNHIIVIRITDNSDSIVILSRSPEESHTTYIYIFNSVRNSDV*FSNCLNERIKVAN 308
FH + + ++ R+ D+ V+L R + + + + V V N L+ERI+V +
Sbjct: 697 FHLVEHDRVIGRVDDDRHVAVVLRRRAQHRRAADVDVLDRVGERAVVLRNRLDERIQVHD 756
Query: 307 ---DHAYHFKVLTLHILLIGVRKSSQYAGVNSRM*GLHTASKHFRRFSNI*DVKDRKSCV 137
D + LH+L G + + A V+ R+ LH +HFR + D ++ V
Sbjct: 757 EQVDRRNPVRFERLHVL--GQVAAGEDAAVHLRVQRLHAPIEHFREAGVVGHFGDGQARV 814
Query: 136 PQRSRCATATN*LKTHFRQSFA*NQQARLI 47
++ R A L Q F A L+
Sbjct: 815 GEQFRGAARRQQLDAERGQRFREVDDAGLV 844
>UniRef50_A5WHB8 Cluster: Short-chain dehydrogenase/reductase SDR;
n=11; Gammaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
Length = 258
Score = 37.1 bits (82), Expect = 0.30
Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Frame = +2
Query: 20 GKLALLSVSDKTG--LLILGKALSEMGL---QLVGSGGTATALRNAGLSVLDVSDITKAP 184
G++A L+ + K G +L+LGK LS++ ++ +GG A+ L SD+ +
Sbjct: 36 GRVAALTYA-KYGATVLLLGKTLSKLEAVYDEIEAAGGKQPAIMPMNLESASYSDMQQLA 94
Query: 185 EMLGGRVKTLHPAVH-AGILARLSNTDQEDM 274
++ + TLH +H AGIL L+ + D+
Sbjct: 95 NLIQSEIGTLHGVLHNAGILGALTPLEMYDV 125
>UniRef50_A5WES0 Cluster: UvrD/REP helicase; n=1; Psychrobacter sp.
PRwf-1|Rep: UvrD/REP helicase - Psychrobacter sp. PRwf-1
Length = 1496
Score = 35.9 bits (79), Expect = 0.70
Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 1/119 (0%)
Frame = +2
Query: 206 KTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENID 385
K + P+ G+LAR ++D+KR E++ + V T+ SDV++ + + D
Sbjct: 736 KPIQPS-DIGVLARA----KKDLKRVEDELVKLNVA-------TLTTSDVSIFETIMAED 783
Query: 386 IGGVTLLRAAAKNHDRVTVICDPNDYDVIINEMK-QSKDHQTSAETRQRLALKAFTHTS 559
+ + HD + + + Y + I E+K DH++ A+K HT+
Sbjct: 784 VAALLSAMLYPYRHDMINRVLTSHLYGLSIKEVKAMMTDHESGVAQSDEAAVKVAAHTN 842
>UniRef50_A6W2K1 Cluster: Carbamoyl-phosphate synthase, large subunit
precursor; n=16; cellular organisms|Rep:
Carbamoyl-phosphate synthase, large subunit precursor -
Marinomonas sp. MWYL1
Length = 1071
Score = 35.5 bits (78), Expect = 0.93
Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
Frame = +2
Query: 5 DMASNGKLALLSVSD--KTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITK 178
++ ++G+ A +SV D K G + + + L+E+G LVG+ GTA L G+ V V+ + +
Sbjct: 937 ELPTSGR-AFISVRDMDKEGAVEVARRLAELGFDLVGTEGTAKYLTERGVEVRKVNKVNE 995
>UniRef50_A6PN14 Cluster: D-alanine--D-alanine ligase precursor;
n=1; Victivallis vadensis ATCC BAA-548|Rep:
D-alanine--D-alanine ligase precursor - Victivallis
vadensis ATCC BAA-548
Length = 702
Score = 35.5 bits (78), Expect = 0.93
Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Frame = +2
Query: 62 LILGKALSEMGLQLVGSGGTATALRNAG--LSVLDVSDITKAPEMLGGRVKTLHPAVHAG 235
L+LG A +E + L A ALRN G ++V DV++ PEM V ++P +H G
Sbjct: 319 LLLGGASNEREISLKSGSAVAQALRNGGFDVTVTDVTECRLLPEMREADV--VYPVLHGG 376
>UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IMP
cyclohydrolase PurH (only IMP cyclohydrolase domain in
Aful); n=1; Magnetospirillum magnetotacticum MS-1|Rep:
COG0138: AICAR transformylase/IMP cyclohydrolase PurH
(only IMP cyclohydrolase domain in Aful) -
Magnetospirillum magnetotacticum MS-1
Length = 50
Score = 35.1 bits (77), Expect = 1.2
Identities = 19/40 (47%), Positives = 22/40 (55%)
Frame = +2
Query: 29 ALLSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGL 148
ALLSVSDKTGL AL G++LV + AGL
Sbjct: 4 ALLSVSDKTGLTDFAAALIGQGVELVSTAAPIARXHRAGL 43
>UniRef50_UPI000034F4E7 Cluster: unknown protein; n=1; Arabidopsis
thaliana|Rep: unknown protein - Arabidopsis thaliana
Length = 1231
Score = 34.3 bits (75), Expect = 2.2
Identities = 15/34 (44%), Positives = 19/34 (55%)
Frame = +2
Query: 401 LLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDH 502
L + K HDRVTV +PND D E + KD+
Sbjct: 576 LFKYVHKGHDRVTVTVEPNDQDTAKKEKDEVKDY 609
>UniRef50_A5BDL1 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 800
Score = 34.3 bits (75), Expect = 2.2
Identities = 23/73 (31%), Positives = 37/73 (50%)
Frame = +2
Query: 122 ATALRNAGLSVLDVSDITKAPEMLGGRVKTLHPAVHAGILARLSNTDQEDMKRQNFEMIS 301
+T LR L ++ D + P M G +++ L P+ A + LS+ D + K NF IS
Sbjct: 490 STPLRAPNLVIVSQGD-AEFPPMGGFQIEGLSPSKMAKVCEVLSSLDIKTKKITNFRPIS 548
Query: 302 VVVCNLYPFVQTV 340
++ C LY + V
Sbjct: 549 LITC-LYKLIAKV 560
>UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase
pyrimidine-specific large chain; n=32; Firmicutes|Rep:
Carbamoyl-phosphate synthase pyrimidine-specific large
chain - Lactobacillus plantarum
Length = 1058
Score = 34.3 bits (75), Expect = 2.2
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Frame = +2
Query: 14 SNGKLAL-LSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEM 190
S+G + L + DK + L K +G QL+ + GTATAL GL V V I
Sbjct: 934 SHGNVLLTVRDEDKPETVALAKRFHALGYQLLATRGTATALTTHGLPVTTVDKID----- 988
Query: 191 LGGRVKTLHPAVHAGILARLSNTDQEDMKRQN 286
G LH + AG + + NT ++ + +N
Sbjct: 989 -SGERDLLH-RMEAGEIQVVINTVSDEEQAEN 1018
>UniRef50_Q28PE6 Cluster: Methyltransferase type 12; n=1; Jannaschia
sp. CCS1|Rep: Methyltransferase type 12 - Jannaschia sp.
(strain CCS1)
Length = 203
Score = 33.9 bits (74), Expect = 2.8
Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Frame = +2
Query: 107 GSGGTATALRNAGLSVLDVSDITKAPEMLG-GRVKTLHPAVHAGI 238
G+G + ALR AG + +D +DI +PEML R K L+ +H GI
Sbjct: 65 GTGLSGAALRAAGFARIDGTDI--SPEMLDVARYKALYDTLHLGI 107
>UniRef50_A4X3R2 Cluster: Putative uncharacterized protein; n=1;
Salinispora tropica CNB-440|Rep: Putative
uncharacterized protein - Salinispora tropica CNB-440
Length = 471
Score = 33.9 bits (74), Expect = 2.8
Identities = 19/67 (28%), Positives = 33/67 (49%)
Frame = +2
Query: 185 EMLGGRVKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVA 364
E L G + A+H G L L T ++D++R F+M+S + + + F +T + V
Sbjct: 57 ERLVGVTDEVIAALHPGNLRDLPFTTKDDLRRAQFDMLSRPLSDAWIFYETTGTTGVATP 116
Query: 365 DAVENID 385
N+D
Sbjct: 117 CPRTNVD 123
>UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chain;
n=38; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Zymomonas mobilis
Length = 1112
Score = 33.9 bits (74), Expect = 2.8
Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
Frame = +2
Query: 44 SDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVKTLHPA 223
SDK ++ KAL+++G++LV + GTA L++ G+ V V+ + + + +K
Sbjct: 988 SDKAQIVEPIKALTDLGIKLVATDGTARYLQSKGVPVERVNKVREGRPHIVDLIKD---- 1043
Query: 224 VHAGILARLSNTDQEDMKRQNFEMI-SVVVCNLYPFVQTVAKSDVTVADAV 373
G ++ + NT + Q+ I S VV P+ T A + + A+A+
Sbjct: 1044 ---GAISLVVNTTEGWQSLQDSASIRSSVVLAPVPYFTTAAAA-IVAAEAI 1090
>UniRef50_A6NS15 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 1098
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/50 (30%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Frame = +2
Query: 47 DKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKA-PEML 193
DK ++ + + +++MG++++ + GTA AL AG+ V+ +++A P +L
Sbjct: 980 DKGEIVGIARGMADMGIEILATSGTADALEAAGVQCRRVARVSEAHPNIL 1029
>UniRef50_Q5A9A3 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 102
Score = 33.5 bits (73), Expect = 3.8
Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Frame = -3
Query: 222 AGCKVFTRPPSISGALVISETSRTESPAFLSAVAVPPLPTS*RPISDKA-LPKIS-KPVL 49
AGC + + S +GAL S+ + + S LSA A+ +P +P + A LP I PV
Sbjct: 34 AGCWLSSASSSSAGALEKSDPNNSTSLLILSAAALIGIPVQWKPNGNNALLPFILWNPVA 93
Query: 48 SDTLSN 31
+ TL N
Sbjct: 94 NSTLDN 99
>UniRef50_A6Q2L8 Cluster: Flagellar P-ring protein FlgI; n=1;
Nitratiruptor sp. SB155-2|Rep: Flagellar P-ring protein
FlgI - Nitratiruptor sp. (strain SB155-2)
Length = 363
Score = 33.1 bits (72), Expect = 5.0
Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +2
Query: 230 AGILARLS-NTDQEDMKRQNFEMISVVVCNLYPFVQTVAKSDVTVADAVENIDIGGVTLL 406
A +L ++ N D +D+K +N + +V L PF ++ DVTV+ + DIG L+
Sbjct: 62 ANMLKKMGINIDPKDVKTKNAAAV-IVTAKLPPFAKSGMTVDVTVSSMGDAKDIGNGVLI 120
Query: 407 RAAAKNHDR 433
R D+
Sbjct: 121 RTPLFGPDK 129
>UniRef50_A4BEW0 Cluster: Putative uncharacterized protein; n=1;
Reinekea sp. MED297|Rep: Putative uncharacterized
protein - Reinekea sp. MED297
Length = 328
Score = 33.1 bits (72), Expect = 5.0
Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Frame = +2
Query: 146 LSVLD-VSDITKAPEMLGGRVKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLY 322
+S +D +SD+ +APEML ++L ++ + + LS D +RQ +M+ + L
Sbjct: 119 VSAMDRLSDLIEAPEMLSIERQSLDVSMLSDLNRSLSYCDVRIARRQAMQMVETI--RLQ 176
Query: 323 PFVQTVAKSDVT 358
F+Q +A D T
Sbjct: 177 AFLQPLAGDDET 188
>UniRef50_UPI00015545E8 Cluster: PREDICTED: similar to smooth muscle
myosin heavy chain 11 isoform SM1-like; n=3;
Mammalia|Rep: PREDICTED: similar to smooth muscle myosin
heavy chain 11 isoform SM1-like - Ornithorhynchus
anatinus
Length = 1077
Score = 32.7 bits (71), Expect = 6.6
Identities = 20/77 (25%), Positives = 34/77 (44%)
Frame = +2
Query: 158 DVSDITKAPEMLGGRVKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFVQT 337
D+SD + L +K H + S D E K + FE++ V ++ PF QT
Sbjct: 612 DISDTNQVEAALKISLKNNH-VTSQKVSPSESGLDGEQCKTEQFELLKVREYDVLPFKQT 670
Query: 338 VAKSDVTVADAVENIDI 388
+K +D + +D+
Sbjct: 671 SSKVQEECSDTMGEVDL 687
>UniRef50_A1ANW7 Cluster: Glycosyl transferase, group 1; n=2;
Desulfuromonadales|Rep: Glycosyl transferase, group 1 -
Pelobacter propionicus (strain DSM 2379)
Length = 399
Score = 32.7 bits (71), Expect = 6.6
Identities = 21/49 (42%), Positives = 27/49 (55%)
Frame = +2
Query: 50 KTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLG 196
K +L +G+A E + LVGS A + R +SV V DI APE LG
Sbjct: 216 KLRILYVGRASEEKRVHLVGSIAAACSQRGLAVSVTLVGDI--APETLG 262
>UniRef50_A5BSI2 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 588
Score = 32.7 bits (71), Expect = 6.6
Identities = 23/76 (30%), Positives = 35/76 (46%)
Frame = +2
Query: 152 VLDVSDITKAPEMLGGRVKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNLYPFV 331
++ V D E + G+ + P G+ + S+ D ED + QNF + ++YP
Sbjct: 242 LIPVKDKETETEAVSGKSSSSSPGDVLGLGSYASDDDDEDDEVQNFSALDSRENSVYPQS 301
Query: 332 QTVAKSDVTVADAVEN 379
SD V DAVEN
Sbjct: 302 SMKXFSD-NVPDAVEN 316
>UniRef50_A4S0E5 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 816
Score = 32.7 bits (71), Expect = 6.6
Identities = 22/61 (36%), Positives = 30/61 (49%)
Frame = +2
Query: 86 EMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVKTLHPAVHAGILARLSNTDQ 265
E+ LQL+G + + + V V K E++ GRVK LH V GIL RL +
Sbjct: 77 ELQLQLLGEDLSMSLEERSREGVARVPKAVKEIEVVEGRVKRLHEEVR-GILDRLDEVES 135
Query: 266 E 268
E
Sbjct: 136 E 136
>UniRef50_A7EYF3 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 1515
Score = 32.7 bits (71), Expect = 6.6
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 401 LLRAAAKNHDRVTVICDPNDYDVIINEMKQSKDHQT-SAETRQRLALKAFTHTSEYDLAI 577
LLR+A N D + +C + + ++ + KDHQ TR+R +L F S +I
Sbjct: 1248 LLRSALVNADFLAFLCMEMSIEQYVTDLTEGKDHQIHETHTRRRFSLVNFLRHSSATFSI 1307
>UniRef50_Q2JDI9 Cluster: Glycine--tRNA ligase; n=21; cellular
organisms|Rep: Glycine--tRNA ligase - Frankia sp.
(strain CcI3)
Length = 1017
Score = 32.3 bits (70), Expect = 8.7
Identities = 18/56 (32%), Positives = 27/56 (48%)
Frame = +2
Query: 59 LLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKAPEMLGGRVKTLHPAV 226
L +LG+ + + + + +G T R AG LDV + PE+L R L P V
Sbjct: 470 LALLGETVVPVTVSTLAAGRTTRGHRRAGSPPLDVPSASGYPELLAARSILLDPVV 525
>UniRef50_O14102 Cluster: Spliceosome-associated protein 49; n=2;
Ascomycota|Rep: Spliceosome-associated protein 49 -
Schizosaccharomyces pombe (Fission yeast)
Length = 335
Score = 32.3 bits (70), Expect = 8.7
Identities = 19/62 (30%), Positives = 32/62 (51%)
Frame = -3
Query: 204 TRPPSISGALVISETSRTESPAFLSAVAVPPLPTS*RPISDKALPKISKPVLSDTLSNAN 25
T PP S A + TS +PA ++A ++PP+P + A+P +S P + + +
Sbjct: 209 TLPPGFSPATP-APTSAANTPATIAATSIPPVPNVPLVGATTAVPPLSIPNVLPFTAAQH 267
Query: 24 FP 19
FP
Sbjct: 268 FP 269
>UniRef50_O27077 Cluster: Carbamoyl-phosphate synthase large chain;
n=34; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Methanobacterium
thermoautotrophicum
Length = 1060
Score = 32.3 bits (70), Expect = 8.7
Identities = 31/135 (22%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Frame = +2
Query: 5 DMASNGKLAL-LSVSDKTGLLILGKALSEMGLQLVGSGGTATALRNAGLSVLDVSDITKA 181
D+ + GK+ + + DK + + K E+G +++ + GTA A V D++DI
Sbjct: 926 DLLNEGKVFISVRDQDKDKIADIVKKADELGFRIMATRGTARA-------VSDIADIEVV 978
Query: 182 PEMLGGRVKTLHPAVHAGILARLSNTDQEDMKRQNFEMISVVVCNL-YPFVQTVAKSDVT 358
++ G + A+ G + + NT + +I + L P+V T+A +
Sbjct: 979 RKVSQGS-PNIRDAILDGEVGLIINTPSGKQSADDGYLIRRMAVELGIPYVTTLAGARAA 1037
Query: 359 VADAVENIDIGGVTL 403
+ +A+E + +G +T+
Sbjct: 1038 L-NAIEAVRMGKITV 1051
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 537,690,617
Number of Sequences: 1657284
Number of extensions: 9649291
Number of successful extensions: 30872
Number of sequences better than 10.0: 77
Number of HSP's better than 10.0 without gapping: 29880
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30763
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 40820699206
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -