Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0001_N01
(624 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant Gau... 56 2e-12
AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant prot... 56 2e-12
D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator pr... 56 2e-12
M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein. 56 2e-12
J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein. 56 2e-12
J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator pr... 56 2e-12
BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant Gau... 56 2e-12
BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant Gau... 56 2e-12
BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant Gau... 56 2e-12
BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant Gau... 56 2e-12
AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant Gau... 56 2e-12
AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant Gau... 56 2e-12
CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein. 56 9e-12
M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate activ... 56 2e-11
M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate activ... 56 3e-11
M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate activ... 56 4e-11
X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate activ... 56 1e-07
BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein. 56 1e-07
DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein... 48 4e-05
BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein. 48 4e-05
AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens ... 48 4e-05
X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate activ... 36 0.15
M24461-1|AAB59541.1| 381|Homo sapiens pulmonary surfactant-asso... 32 1.4
DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant pu... 32 1.4
AF400074-1|AAK77913.1| 381|Homo sapiens surfactant, pulmonary-a... 32 1.4
BC039729-1|AAH39729.1| 516|Homo sapiens RIOK3 protein protein. 31 2.5
BC028360-1|AAH28360.1| 424|Homo sapiens RIO kinase 3 (yeast) pr... 31 2.5
AF013591-1|AAC26080.1| 519|Homo sapiens homolog of the Aspergil... 31 2.5
>AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 559
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant
protein.
Length = 530
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 298 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 356
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 357 KSLSEECQEVVDTYGSSILSILLEEVSP 384
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 399 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 458
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 459 QFVAEYEPVLIEILVEVMDPS 479
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 66 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 125
Query: 575 QEI 583
E+
Sbjct: 126 GEM 128
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLV--ADLKPAAICKMIGICAGNATDVPVSPLLPK 205
C + G D C + QY + ++ D +P IC ++G C ++P+ L+P
Sbjct: 233 CDRLGPGMADICKNYISQYSEIAIQMMMHMQDQQPKEICALVGFC-DEVKEMPMQTLVPA 291
Query: 206 ELIIKAITPSSKLI 247
++ K + P+ +L+
Sbjct: 292 KVASKNVIPALELV 305
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 341 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 396
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 453 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 488
>D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator
proteins protein.
Length = 527
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 295 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 353
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 354 KSLSEECQEVVDTYGSSILSILLEEVSP 381
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 396 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 455
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 456 QFVAEYEPVLIEILVEVMDPS 476
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLV--ADLKPAAICKMIGICAGNATDVPVSPLLPK 205
C + G D C + QY + ++ D +P IC ++G C ++P+ L+P
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMMHMQDQQPKEICALVGFC-DEVKEMPMQTLVPA 288
Query: 206 ELIIKAITPSSKLI 247
++ K + P+ +L+
Sbjct: 289 KVASKNVIPALELV 302
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 338 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 393
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 450 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 485
>M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein.
Length = 524
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator
precursor protein.
Length = 524
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) v protein.
Length = 524
Score = 56.4 bits (130), Expect(2) = 2e-12
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 2e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 54.4 bits (125), Expect(2) = 9e-12
Identities = 25/88 (28%), Positives = 52/88 (59%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG ++ ++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSIPSILLEEVSP 378
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 35.1 bits (77), Expect(2) = 9e-12
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +2
Query: 35 CKQTGE-FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNATDVPVSPLLPKEL 211
C + G D C + QY + ++ ++P IC ++G C ++P+ L+P ++
Sbjct: 230 CDRLGPGMADICKNYISQYSEIAIQMMM-HMQPKEICALVGFC-DEVKEMPMQTLVPAKV 287
Query: 212 IIKAITPSSKLI 247
K + P+ +L+
Sbjct: 288 ASKNVIPALELV 299
Score = 32.3 bits (70), Expect = 1.4
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIPSILLEEVSPELVCSMLHLCSG 390
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 526
Score = 56.4 bits (130), Expect(2) = 2e-11
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 294 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 352
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 353 KSLSEECQEVVDTYGSSILSILLEEVSP 380
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 395 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 454
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 455 QFVAEYEPVLIEILVEVMDPS 475
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 337 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 392
Score = 31.9 bits (69), Expect(2) = 2e-11
Identities = 14/56 (25%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Frame = +2
Query: 83 QYYPVIYNFLV-ADLKPAAICKMIGICAGNATDVPVSPLLPKELIIKAITPSSKLI 247
QY + ++ D +P IC ++G C ++P+ L+P ++ K + P+ +L+
Sbjct: 247 QYSEIAIQMMMHMDQQPKEICALVGFC-DEVKEMPMQTLVPAKVASKNVIPALELV 301
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 449 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 484
>M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 527
Score = 56.4 bits (130), Expect(2) = 3e-11
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 295 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 353
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 354 KSLSEECQEVVDTYGSSILSILLEEVSP 381
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 396 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 455
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 456 QFVAEYEPVLIEILVEVMDPS 476
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 338 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 393
Score = 31.5 bits (68), Expect(2) = 3e-11
Identities = 12/43 (27%), Positives = 25/43 (58%)
Frame = +2
Query: 119 DLKPAAICKMIGICAGNATDVPVSPLLPKELIIKAITPSSKLI 247
D +P IC ++G C ++P+ L+P ++ K + P+ +L+
Sbjct: 261 DQQPKEICALVGFC-DEVKEMPMQTLVPAKVASKNVIPALELV 302
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 450 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 485
>M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 524
Score = 56.4 bits (130), Expect(2) = 4e-11
Identities = 25/88 (28%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Frame = +2
Query: 338 IVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLP 505
++PAL PI++ V ++ V C C++ + + + +++ E ++ A + C LP
Sbjct: 292 VIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP 350
Query: 506 ASVNAECKEFVDQYGPAVIALLVQEIDP 589
S++ EC+E VD YG +++++L++E+ P
Sbjct: 351 KSLSEECQEVVDTYGSSILSILLEEVSP 378
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 453 QFVAEYEPVLIEILVEVMDPS 473
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 575 QEI 583
E+
Sbjct: 123 GEM 125
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 335 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 390
Score = 31.1 bits (67), Expect(2) = 4e-11
Identities = 11/46 (23%), Positives = 27/46 (58%)
Frame = +2
Query: 110 LVADLKPAAICKMIGICAGNATDVPVSPLLPKELIIKAITPSSKLI 247
++ ++P IC ++G C ++P+ L+P ++ K + P+ +L+
Sbjct: 255 MMMHMQPKEICALVGFC-DEVKEMPMQTLVPAKVASKNVIPALELV 299
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 447 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 482
>X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate
activator protein.
Length = 210
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 90 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 149
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 150 QFVAEYEPVLIEILVEVMDPS 170
Score = 54.4 bits (125), Expect = 3e-07
Identities = 19/69 (27%), Positives = 43/69 (62%)
Frame = +2
Query: 383 QNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 562
++ V C C++ + + + +++ E ++ A + C LP S++ EC+E VD YG +++
Sbjct: 7 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 66
Query: 563 ALLVQEIDP 589
++L++E+ P
Sbjct: 67 SILLEEVSP 75
Score = 33.1 bits (72), Expect = 0.82
Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLC-KQTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAG 166
E E +C K +EC + + Y I + L+ ++ P +C M+ +C+G
Sbjct: 32 EKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG 87
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 144 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 179
>BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein.
Length = 240
Score = 56.0 bits (129), Expect = 1e-07
Identities = 25/81 (30%), Positives = 43/81 (53%)
Frame = +2
Query: 350 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 529
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 109 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 168
Query: 530 EFVDQYGPAVIALLVQEIDPS 592
+FV +Y P +I +LV+ +DPS
Sbjct: 169 QFVAEYEPVLIEILVEVMDPS 189
Score = 30.7 bits (66), Expect = 4.4
Identities = 11/36 (30%), Positives = 19/36 (52%)
Frame = +2
Query: 53 FKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGIC 160
++ +C +Y PV+ LV + P+ +C IG C
Sbjct: 163 YQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 198
>DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein 1
protein.
Length = 521
Score = 47.6 bits (108), Expect = 4e-05
Identities = 24/68 (35%), Positives = 34/68 (50%)
Frame = +2
Query: 392 VVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALL 571
V C C + L L + E +T A+ C V+PAS+ EC VD Y P+++ L
Sbjct: 292 VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-L 350
Query: 572 VQEIDPSK 595
V +I P K
Sbjct: 351 VAKITPEK 358
Score = 41.5 bits (93), Expect = 0.002
Identities = 19/64 (29%), Positives = 27/64 (42%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQ 577
C+ C+ L L + + A C +LP +CK FV QY P +I L
Sbjct: 396 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 455
Query: 578 EIDP 589
+DP
Sbjct: 456 MMDP 459
Score = 37.9 bits (84), Expect = 0.029
Identities = 15/38 (39%), Positives = 20/38 (52%)
Frame = +2
Query: 62 ECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNAT 175
+C H QY PV+ L + P A+CK +G C G T
Sbjct: 437 QCKHFVTQYEPVLIESLKDMMDPVAVCKKVGACHGPRT 474
Score = 32.3 bits (70), Expect = 1.4
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLCK-QTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGN 169
EL L+ +C EC+ L + Y P + LVA + P +CK I +C GN
Sbjct: 314 ELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-LVAKITPEKVCKFIRLC-GN 368
>BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein.
Length = 543
Score = 47.6 bits (108), Expect = 4e-05
Identities = 24/68 (35%), Positives = 34/68 (50%)
Frame = +2
Query: 392 VVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALL 571
V C C + L L + E +T A+ C V+PAS+ EC VD Y P+++ L
Sbjct: 314 VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-L 372
Query: 572 VQEIDPSK 595
V +I P K
Sbjct: 373 VAKITPEK 380
Score = 41.5 bits (93), Expect = 0.002
Identities = 19/64 (29%), Positives = 27/64 (42%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQ 577
C+ C+ L L + + A C +LP +CK FV QY P +I L
Sbjct: 418 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 477
Query: 578 EIDP 589
+DP
Sbjct: 478 MMDP 481
Score = 37.9 bits (84), Expect = 0.029
Identities = 15/38 (39%), Positives = 20/38 (52%)
Frame = +2
Query: 62 ECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNAT 175
+C H QY PV+ L + P A+CK +G C G T
Sbjct: 459 QCKHFVTQYEPVLIESLKDMMDPVAVCKKVGACHGPRT 496
Score = 32.3 bits (70), Expect = 1.4
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLCK-QTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGN 169
EL L+ +C EC+ L + Y P + LVA + P +CK I +C GN
Sbjct: 336 ELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-LVAKITPEKVCKFIRLC-GN 390
>AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens
cDNA FLJ40379 fis, clone TESTI2035262, weakly similar to
PROACTIVATOR POLYPEPTIDE PRECURSOR. ).
Length = 241
Score = 47.6 bits (108), Expect = 4e-05
Identities = 24/68 (35%), Positives = 34/68 (50%)
Frame = +2
Query: 392 VVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALL 571
V C C + L L + E +T A+ C V+PAS+ EC VD Y P+++ L
Sbjct: 24 VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-L 82
Query: 572 VQEIDPSK 595
V +I P K
Sbjct: 83 VAKITPEK 90
Score = 41.5 bits (93), Expect = 0.002
Identities = 19/64 (29%), Positives = 27/64 (42%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQ 577
C+ C+ L L + + A C +LP +CK FV QY P +I L
Sbjct: 128 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 187
Query: 578 EIDP 589
+DP
Sbjct: 188 MMDP 191
Score = 37.9 bits (84), Expect = 0.029
Identities = 15/38 (39%), Positives = 20/38 (52%)
Frame = +2
Query: 62 ECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGNAT 175
+C H QY PV+ L + P A+CK +G C G T
Sbjct: 169 QCKHFVTQYEPVLIESLKDMMDPVAVCKKVGACHGPRT 206
Score = 32.3 bits (70), Expect = 1.4
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Frame = +2
Query: 2 ELEFYKVLQGLCK-QTGEFKDECLHLAEQYYPVIYNFLVADLKPAAICKMIGICAGN 169
EL L+ +C EC+ L + Y P + LVA + P +CK I +C GN
Sbjct: 46 ELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-LVAKITPEKVCKFIRLC-GN 100
>X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate
activator protein.
Length = 67
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 574
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 5 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 64
Query: 575 QEI 583
E+
Sbjct: 65 GEM 67
>M24461-1|AAB59541.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Frame = +2
Query: 395 VCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASV-NAECKEFVDQYGPAVIALL 571
+C C+ +H L ++ + + + C VLP + +C + +D Y P VI
Sbjct: 68 LCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127
Query: 572 VQEID 586
+ID
Sbjct: 128 QNQID 132
>DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant
pulmonary-associated protein B protein.
Length = 147
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Frame = +2
Query: 395 VCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASV-NAECKEFVDQYGPAVIALL 571
+C C+ +H L ++ + + + C VLP + +C + +D Y P VI
Sbjct: 64 LCQECEDIVHILNKMAKEAIFQDTMREFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 123
Query: 572 VQEID 586
+ID
Sbjct: 124 QNQID 128
>AF400074-1|AAK77913.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Frame = +2
Query: 395 VCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASV-NAECKEFVDQYGPAVIALL 571
+C C+ +H L ++ + + + C VLP + +C + +D Y P VI
Sbjct: 68 LCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127
Query: 572 VQEID 586
+ID
Sbjct: 128 QNQID 132
>BC039729-1|AAH39729.1| 516|Homo sapiens RIOK3 protein protein.
Length = 516
Score = 31.5 bits (68), Expect = 2.5
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +2
Query: 308 VIGEAEPEPGIVPALPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNA 487
++G A PEPG A + ++PQN + CS L EL EA V V
Sbjct: 3 LVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKEL-QLEEEAAVFPEVAV 61
Query: 488 ACG 496
A G
Sbjct: 62 AEG 64
>BC028360-1|AAH28360.1| 424|Homo sapiens RIO kinase 3 (yeast)
protein.
Length = 424
Score = 31.5 bits (68), Expect = 2.5
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +2
Query: 308 VIGEAEPEPGIVPALPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNA 487
++G A PEPG A + ++PQN + CS L EL EA V V
Sbjct: 3 LVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKEL-QLEEEAAVFPEVAV 61
Query: 488 ACG 496
A G
Sbjct: 62 AEG 64
>AF013591-1|AAC26080.1| 519|Homo sapiens homolog of the Aspergillus
nidulans sudD gene product protein.
Length = 519
Score = 31.5 bits (68), Expect = 2.5
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +2
Query: 308 VIGEAEPEPGIVPALPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNA 487
++G A PEPG A + ++PQN + CS L EL EA V V
Sbjct: 3 LVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKEL-QLEEEAAVFPEVAV 61
Query: 488 ACG 496
A G
Sbjct: 62 AEG 64
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 83,521,302
Number of Sequences: 237096
Number of extensions: 1679353
Number of successful extensions: 3767
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 3538
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3767
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6747805200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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