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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= I10A02NGRL0001_M17
         (606 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AL583862-8|CAI14893.1|  247|Homo sapiens hydroxypyruvate isomera...   126   5e-29
AY775560-1|AAV84474.1|  229|Homo sapiens endothelial cell apopto...   124   2e-28
BC019041-1|AAH19041.1|  174|Homo sapiens HYI protein protein.          74   5e-13
BC006140-1|AAH06140.1|  217|Homo sapiens HYI protein protein.          74   5e-13
AL583862-5|CAI14890.1|  204|Homo sapiens hydroxypyruvate isomera...    74   5e-13
AF284751-1|AAG59853.1|  174|Homo sapiens HT036 protein.                74   5e-13
AF284750-1|AAG59852.1|  204|Homo sapiens HT036-ISO protein.            74   5e-13
AL583862-7|CAI14892.1|  165|Homo sapiens hydroxypyruvate isomera...    56   1e-07
AL583862-4|CAI14889.1|  180|Homo sapiens hydroxypyruvate isomera...    50   6e-06
AL583862-6|CAI14891.1|  229|Homo sapiens hydroxypyruvate isomera...    49   1e-05

>AL583862-8|CAI14893.1|  247|Homo sapiens hydroxypyruvate isomerase
           homolog (E. coli) protein.
          Length = 247

 Score =  126 bits (305), Expect = 5e-29
 Identities = 70/180 (38%), Positives = 107/180 (59%), Gaps = 7/180 (3%)
 Frame = +3

Query: 48  MKFCANLSFMFAEASSILERYALARDAGFKAVESGFPFGCTLEQVKQAKENAGVEQVCIN 227
           ++F ANLS++F E S +  R   A  +GF+AVE  +P+  T E + +A   AG+  V IN
Sbjct: 4   LRFSANLSWLFPELSGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLIN 63

Query: 228 LKTGDTTKGEVGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK----- 392
              GD  KGE+G+ +VPG++  F++ L+  + YAKA+   +IH+MAG V +   +     
Sbjct: 64  TPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKA 123

Query: 393 HWE-TFESNLKYAVDVLKGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSPNLKI 566
             E  F  NL++A  VL  E L+GL+EPIN + + P YFL    +A  IL ++  PNL++
Sbjct: 124 EMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 183


>AY775560-1|AAV84474.1|  229|Homo sapiens endothelial cell apoptosis
           protein E-CE1 protein.
          Length = 229

 Score =  124 bits (300), Expect = 2e-28
 Identities = 69/180 (38%), Positives = 106/180 (58%), Gaps = 7/180 (3%)
 Frame = +3

Query: 48  MKFCANLSFMFAEASSILERYALARDAGFKAVESGFPFGCTLEQVKQAKENAGVEQVCIN 227
           ++F ANLS++F E   +  R   A  +GF+AVE  +P+  T E + +A   AG+  V IN
Sbjct: 4   LRFSANLSWLFPELPGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLIN 63

Query: 228 LKTGDTTKGEVGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK----- 392
              GD  KGE+G+ +VPG++  F++ L+  + YAKA+   +IH+MAG V +   +     
Sbjct: 64  TPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKA 123

Query: 393 HWE-TFESNLKYAVDVLKGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSPNLKI 566
             E  F  NL++A  VL  E L+GL+EPIN + + P YFL    +A  IL ++  PNL++
Sbjct: 124 EMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 183


>BC019041-1|AAH19041.1|  174|Homo sapiens HYI protein protein.
          Length = 174

 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 41/110 (37%), Positives = 66/110 (60%), Gaps = 7/110 (6%)
 Frame = +3

Query: 258 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWE-TFESNL 419
           +G+ +VPG++  F++ L+  + YAKA+   +IH+MAG V +   +       E  F  NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60

Query: 420 KYAVDVLKGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSPNLKI 566
           ++A  VL  E L+GL+EPIN + + P YFL    +A  IL ++  PNL++
Sbjct: 61  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 110


>BC006140-1|AAH06140.1|  217|Homo sapiens HYI protein protein.
          Length = 217

 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 41/110 (37%), Positives = 66/110 (60%), Gaps = 7/110 (6%)
 Frame = +3

Query: 258 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWE-TFESNL 419
           +G+ +VPG++  F++ L+  + YAKA+   +IH+MAG V +   +       E  F  NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60

Query: 420 KYAVDVLKGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSPNLKI 566
           ++A  VL  E L+GL+EPIN + + P YFL    +A  IL ++  PNL++
Sbjct: 61  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 110


>AL583862-5|CAI14890.1|  204|Homo sapiens hydroxypyruvate isomerase
           homolog (E. coli) protein.
          Length = 204

 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 41/110 (37%), Positives = 66/110 (60%), Gaps = 7/110 (6%)
 Frame = +3

Query: 258 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWE-TFESNL 419
           +G+ +VPG++  F++ L+  + YAKA+   +IH+MAG V +   +       E  F  NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60

Query: 420 KYAVDVLKGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSPNLKI 566
           ++A  VL  E L+GL+EPIN + + P YFL    +A  IL ++  PNL++
Sbjct: 61  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 110


>AF284751-1|AAG59853.1|  174|Homo sapiens HT036 protein.
          Length = 174

 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 41/110 (37%), Positives = 66/110 (60%), Gaps = 7/110 (6%)
 Frame = +3

Query: 258 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWE-TFESNL 419
           +G+ +VPG++  F++ L+  + YAKA+   +IH+MAG V +   +       E  F  NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60

Query: 420 KYAVDVLKGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSPNLKI 566
           ++A  VL  E L+GL+EPIN + + P YFL    +A  IL ++  PNL++
Sbjct: 61  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 110


>AF284750-1|AAG59852.1|  204|Homo sapiens HT036-ISO protein.
          Length = 204

 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 41/110 (37%), Positives = 66/110 (60%), Gaps = 7/110 (6%)
 Frame = +3

Query: 258 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWE-TFESNL 419
           +G+ +VPG++  F++ L+  + YAKA+   +IH+MAG V +   +       E  F  NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60

Query: 420 KYAVDVLKGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSPNLKI 566
           ++A  VL  E L+GL+EPIN + + P YFL    +A  IL ++  PNL++
Sbjct: 61  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 110


>AL583862-7|CAI14892.1|  165|Homo sapiens hydroxypyruvate isomerase
           homolog (E. coli) protein.
          Length = 165

 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 37/110 (33%), Positives = 61/110 (55%), Gaps = 7/110 (6%)
 Frame = +3

Query: 258 VGVTSVPGKENEFKDNLKTTIDYAKAVNARKIHIMAGIVDKPTPK-----HWET-FESNL 419
           +G+ +VPG++  F++ L+  +         +IH+MAG V +   +       E  F  NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAV---------RIHLMAGRVPQGADRIAVKAEMEAVFLENL 51

Query: 420 KYAVDVLKGESLLGLIEPIN-QYSMPNYFLSDYGRAFGILDRINSPNLKI 566
           ++A  VL  E L+GL+EPIN + + P YFL    +A  IL ++  PNL++
Sbjct: 52  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 101


>AL583862-4|CAI14889.1|  180|Homo sapiens hydroxypyruvate isomerase
           homolog (E. coli) protein.
          Length = 180

 Score = 50.0 bits (114), Expect = 6e-06
 Identities = 31/80 (38%), Positives = 46/80 (57%), Gaps = 7/80 (8%)
 Frame = +3

Query: 348 KIHIMAGIVDKPTPK-----HWET-FESNLKYAVDVLKGESLLGLIEPIN-QYSMPNYFL 506
           +IH+MAG V +   +       E  F  NL++A  VL  E L+GL+EPIN + + P YFL
Sbjct: 37  RIHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFL 96

Query: 507 SDYGRAFGILDRINSPNLKI 566
               +A  IL ++  PNL++
Sbjct: 97  DTPQQAAAILQKVGRPNLQL 116


>AL583862-6|CAI14891.1|  229|Homo sapiens hydroxypyruvate isomerase
           homolog (E. coli) protein.
          Length = 229

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 31/79 (39%), Positives = 45/79 (56%), Gaps = 7/79 (8%)
 Frame = +3

Query: 351 IHIMAGIVDKPTPK-----HWET-FESNLKYAVDVLKGESLLGLIEPIN-QYSMPNYFLS 509
           IH+MAG V +   +       E  F  NL++A  VL  E L+GL+EPIN + + P YFL 
Sbjct: 57  IHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLD 116

Query: 510 DYGRAFGILDRINSPNLKI 566
              +A  IL ++  PNL++
Sbjct: 117 TPQQAAAILQKVGRPNLQL 135


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,523,847
Number of Sequences: 237096
Number of extensions: 1612752
Number of successful extensions: 3348
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3204
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3329
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6410414940
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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