Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0001_L08
(596 letters)
Database: spombe
5004 sequences; 2,362,478 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SPBC1D7.04 |mlo3||RNA annealing factor Mlo3|Schizosaccharomyces ... 57 2e-09
SPBC106.12c |||THO complex subunit |Schizosaccharomyces pombe|ch... 46 3e-06
SPAC328.05 |||RNA-binding protein involved in export of mRNAs|Sc... 46 6e-06
SPAC19G12.07c |rsd1||RNA-binding protein Rsd1|Schizosaccharomyce... 43 3e-05
SPAC19A8.13 |usp101|snp1|U1 snRNP-associated protein Usp101 |Sch... 42 5e-05
SPAC22E12.02 |||RNA-binding protein|Schizosaccharomyces pombe|ch... 40 3e-04
SPAC343.07 |mug28||RNA-binding protein Mug28|Schizosaccharomyces... 40 4e-04
SPBC4F6.14 |||RNA-binding protein|Schizosaccharomyces pombe|chr ... 36 0.006
SPBC29A3.07c |||U2 snRNP-associated protein Sf3b14 homolog |Schi... 36 0.006
SPAC3G6.04 |rnp24||RNA-binding protein Rnp24|Schizosaccharomyces... 34 0.014
SPCC126.11c |||RNA-binding protein, rrm type|Schizosaccharomyces... 34 0.014
SPBC887.05c |cwf29||RNA-binding protein Cwf29|Schizosaccharomyce... 33 0.024
SPAC57A7.04c |pabp||mRNA export shuttling protein |Schizosacchar... 33 0.024
SPBP22H7.02c |||RNA-binding protein Mrd1 |Schizosaccharomyces po... 33 0.032
SPBC18H10.03 |tif35||translation initiation factor eIF3g|Schizos... 32 0.073
SPBC17G9.05 |rct1|cyp6|RRM-containing cyclophilin regulating tra... 31 0.097
SPBC4B4.07c |usp102|mud1|U1 snRNP-associated protein Usp102|Schi... 30 0.29
SPAC23A1.09 |||RNA-binding protein|Schizosaccharomyces pombe|chr... 29 0.52
SPAC13G6.06c |||glycine cleavage complex subunit P|Schizosacchar... 29 0.68
SPBC29A10.02 |spo5|mrb1, mug12, SPBC365.18|meiotic RNA-binding p... 28 0.90
SPBC56F2.08c |||RNA-binding protein|Schizosaccharomyces pombe|ch... 28 1.2
SPAC3A11.14c |pkl1|klp1, SPAC3H5.03c|kinesin-like protein Pkl1|S... 27 2.1
SPAC3F10.06c |||initiator methionine tRNA 2'-O-ribosyl phosphate... 26 3.6
SPACUNK4.16c |||alpha,alpha-trehalose-phosphate synthase |Schizo... 26 3.6
SPBC15D4.11c |||sequence orphan|Schizosaccharomyces pombe|chr 2|... 26 4.8
SPCC23B6.04c |||sec14 cytosolic factor family|Schizosaccharomyce... 25 8.4
>SPBC1D7.04 |mlo3||RNA annealing factor Mlo3|Schizosaccharomyces
pombe|chr 2|||Manual
Length = 199
Score = 56.8 bits (131), Expect = 2e-09
Identities = 28/75 (37%), Positives = 46/75 (61%), Gaps = 1/75 (1%)
Frame = +1
Query: 373 AITTGPSKLLVSNLDFGVSDSDIQELF-SEFGILKSAAVHYDRSGRSLGTADVVFERRAD 549
++ + SK++VSNL V+++ ++ELF G K ++ Y +GRS G A ++F R D
Sbjct: 49 SVISEESKIIVSNLPTDVTEAQVKELFVKSIGPCKRVSLAYGPNGRSKGIATIIFSRPGD 108
Query: 550 ALKAMKQYNGVPLDG 594
A +A +QY G +DG
Sbjct: 109 ATRAYEQYEGRLVDG 123
>SPBC106.12c |||THO complex subunit |Schizosaccharomyces pombe|chr
2|||Manual
Length = 274
Score = 46.4 bits (105), Expect = 3e-06
Identities = 25/64 (39%), Positives = 34/64 (53%)
Frame = +1
Query: 403 VSNLDFGVSDSDIQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADALKAMKQYNGV 582
V NL + V + D+ LF F ++ ++YDR+GRS G+ DV FE DA A K
Sbjct: 89 VENLHYQVLEKDVLSLFENFHPIR-VIMNYDRAGRSEGSCDVYFETSQDAEDAQKTLQST 147
Query: 583 PLDG 594
L G
Sbjct: 148 NLKG 151
>SPAC328.05 |||RNA-binding protein involved in export of
mRNAs|Schizosaccharomyces pombe|chr 1|||Manual
Length = 434
Score = 45.6 bits (103), Expect = 6e-06
Identities = 22/66 (33%), Positives = 37/66 (56%)
Frame = +1
Query: 397 LLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADALKAMKQYN 576
+ V NL + SD ++ +LF++ G + A + Y+ +GRS G V FE DA ++++ N
Sbjct: 282 IYVGNLPWATSDRNLLDLFTDIGSVIRARIAYEPTGRSKGFGVVQFENENDAASSIEKLN 341
Query: 577 GVPLDG 594
G G
Sbjct: 342 GYRYGG 347
Score = 31.1 bits (67), Expect = 0.13
Identities = 16/61 (26%), Positives = 30/61 (49%)
Frame = +1
Query: 412 LDFGVSDSDIQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADALKAMKQYNGVPLD 591
L + V D+++LF + G + A + ++ GRS G VV +A+ A++ +
Sbjct: 190 LPYNVRWQDLKDLFRQAGSVIRADIQMNQEGRSRGIGIVVMSSMKEAMHAIQMLHNTDFM 249
Query: 592 G 594
G
Sbjct: 250 G 250
>SPAC19G12.07c |rsd1||RNA-binding protein Rsd1|Schizosaccharomyces
pombe|chr 1|||Manual
Length = 604
Score = 43.2 bits (97), Expect = 3e-05
Identities = 20/67 (29%), Positives = 35/67 (52%)
Frame = +1
Query: 394 KLLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADALKAMKQY 573
+L VSN+ F ++D D++ +F FG ++ + D RS G + + A A+++
Sbjct: 341 RLCVSNIHFNLTDEDVKAIFEPFGDIEFVHLQRDDQNRSKGFGYIQYRNPISARNALEKM 400
Query: 574 NGVPLDG 594
NG L G
Sbjct: 401 NGFDLAG 407
>SPAC19A8.13 |usp101|snp1|U1 snRNP-associated protein Usp101
|Schizosaccharomyces pombe|chr 1|||Manual
Length = 261
Score = 42.3 bits (95), Expect = 5e-05
Identities = 23/67 (34%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Frame = +1
Query: 397 LLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDR-SGRSLGTADVVFERRADALKAMKQY 573
+ +S L + +SDI+ F+ +G ++ V ++ +G+S+G A VVFER D A K
Sbjct: 102 MFLSRLSYDTKESDIEREFTRYGPIERIRVVRNKVTGKSMGYAFVVFERERDLKVAYKAS 161
Query: 574 NGVPLDG 594
G+ L+G
Sbjct: 162 AGLMLNG 168
>SPAC22E12.02 |||RNA-binding protein|Schizosaccharomyces pombe|chr
1|||Manual
Length = 219
Score = 39.9 bits (89), Expect = 3e-04
Identities = 22/62 (35%), Positives = 32/62 (51%)
Frame = +1
Query: 394 KLLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADALKAMKQY 573
+L V NL V+D + + FSE+ L V DR G++ G V F+ LKA ++
Sbjct: 31 RLFVGNLGNDVNDESLYQAFSEYPSLVKTKVVRDREGKTRGFGFVSFKDSDQFLKAWREK 90
Query: 574 NG 579
NG
Sbjct: 91 NG 92
>SPAC343.07 |mug28||RNA-binding protein Mug28|Schizosaccharomyces
pombe|chr 1|||Manual
Length = 609
Score = 39.5 bits (88), Expect = 4e-04
Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 3/71 (4%)
Frame = +1
Query: 379 TTGPSKLLVSNLDFGV--SDSDIQELFSEFGILKSAAV-HYDRSGRSLGTADVVFERRAD 549
T P L V NLD + + ++ELFS+FG +KS + Y + S G V F +
Sbjct: 415 TIDPCNLFVKNLDDNIVGNTQQLEELFSKFGRIKSCTLASYPSTEISKGYGFVSFSHPFE 474
Query: 550 ALKAMKQYNGV 582
A++A+ NGV
Sbjct: 475 AVQAINTLNGV 485
Score = 26.2 bits (55), Expect = 3.6
Identities = 19/72 (26%), Positives = 28/72 (38%), Gaps = 6/72 (8%)
Frame = +1
Query: 397 LLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDRSGRSLGT------ADVVFERRADALK 558
+ V NL SD+ ELF FG + + +S + A + FE + A
Sbjct: 22 IYVGNLPSTCQSSDLHELFEPFGNFSKFHMLSRKKNKSTDSKSPTLFAFITFENKCSADN 81
Query: 559 AMKQYNGVPLDG 594
A+ NG G
Sbjct: 82 AIASLNGSSFQG 93
>SPBC4F6.14 |||RNA-binding protein|Schizosaccharomyces pombe|chr
2|||Manual
Length = 674
Score = 35.5 bits (78), Expect = 0.006
Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +1
Query: 394 KLLVSNLDFGVSDSD-IQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADALKAMKQ 570
+L++ NL + + ++ FS+FG ++ + GR G A V + R A +AM
Sbjct: 108 RLIIRNLPWSIKKPQHLEPHFSKFGKVREIKIPTKGGGRMCGFAFVWMKDRKAAEEAMNS 167
Query: 571 YNGVPLDG 594
NG +DG
Sbjct: 168 LNGTEIDG 175
>SPBC29A3.07c |||U2 snRNP-associated protein Sf3b14 homolog
|Schizosaccharomyces pombe|chr 2|||Manual
Length = 137
Score = 35.5 bits (78), Expect = 0.006
Identities = 18/63 (28%), Positives = 36/63 (57%)
Frame = +1
Query: 391 SKLLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADALKAMKQ 570
S L + NL F ++ ++ +LF +G ++ + + ++ GTA VV+E DA +A ++
Sbjct: 12 SILFIKNLSFKITAEEMYDLFGRYGPVRQ--IRLGNTVQTRGTAFVVYENVQDARRACEK 69
Query: 571 YNG 579
+G
Sbjct: 70 LSG 72
>SPAC3G6.04 |rnp24||RNA-binding protein Rnp24|Schizosaccharomyces
pombe|chr 1|||Manual
Length = 369
Score = 34.3 bits (75), Expect = 0.014
Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Frame = +1
Query: 388 PSKLL-VSNLDFGVSDSDIQELFSEFG-ILKSAAVHYDRSGRSLGTADVVFERRADALKA 561
PS +L V NLDF +D+D++E F + G I + + ++ +G+ G V F +KA
Sbjct: 226 PSSILFVGNLDFETTDADLKEHFGQVGQIRRVRLMTFEDTGKCKGFGFVDFPDIDTCMKA 285
Query: 562 MK 567
M+
Sbjct: 286 ME 287
>SPCC126.11c |||RNA-binding protein, rrm type|Schizosaccharomyces
pombe|chr 3|||Manual
Length = 183
Score = 34.3 bits (75), Expect = 0.014
Identities = 21/70 (30%), Positives = 35/70 (50%)
Frame = +1
Query: 385 GPSKLLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADALKAM 564
GP+ +++ NL G S D+ FG + + V+ D G+ A V F A A + +
Sbjct: 98 GPTNVVIENLAPGTSSDDVAATLLNFGEILNCQVN-DSQGKV--RASVRFSTLASAQQVV 154
Query: 565 KQYNGVPLDG 594
++ +GV DG
Sbjct: 155 QKLDGVTADG 164
>SPBC887.05c |cwf29||RNA-binding protein Cwf29|Schizosaccharomyces
pombe|chr 2|||Manual
Length = 217
Score = 33.5 bits (73), Expect = 0.024
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Frame = +1
Query: 397 LLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDR-SGRSLGTADVVFERRADALKAMKQY 573
+ + NLDF +++ DI +FSEFG + D+ +G+S G A + +E + + A+
Sbjct: 33 IYIGNLDFDLNEDDILCVFSEFGEPVDINLVRDKETGKSKGFAFLKYEDQRSTVLAVDNM 92
Query: 574 NGVPL 588
V L
Sbjct: 93 TNVKL 97
>SPAC57A7.04c |pabp||mRNA export shuttling protein
|Schizosaccharomyces pombe|chr 1|||Manual
Length = 653
Score = 33.5 bits (73), Expect = 0.024
Identities = 16/68 (23%), Positives = 35/68 (51%)
Frame = +1
Query: 373 AITTGPSKLLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADA 552
A+ + + + NLD +++ + +LF +FG + S ++ D++ + G V + A
Sbjct: 255 ALKANFTNVYIKNLDTEITEQEFSDLFGQFGEITSLSLVKDQNDKPRGFGFVNYANHECA 314
Query: 553 LKAMKQYN 576
KA+ + N
Sbjct: 315 QKAVDELN 322
>SPBP22H7.02c |||RNA-binding protein Mrd1 |Schizosaccharomyces
pombe|chr 2|||Manual
Length = 833
Score = 33.1 bits (72), Expect = 0.032
Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 6/72 (8%)
Frame = +1
Query: 397 LLVSNLDFGVSDSDIQELFSEFGILKSAAVHYD----RSGR--SLGTADVVFERRADALK 558
+ V NL+F + Q++F SA + R G+ S+G V F+ +A A+
Sbjct: 621 IYVKNLNFSTKQEEFQKVFKPLEGYLSAVIRAKPDPKRPGKYLSMGFGFVEFKDKASAVA 680
Query: 559 AMKQYNGVPLDG 594
AM NG LDG
Sbjct: 681 AMHAMNGFVLDG 692
Score = 27.1 bits (57), Expect = 2.1
Identities = 12/25 (48%), Positives = 15/25 (60%)
Frame = +1
Query: 397 LLVSNLDFGVSDSDIQELFSEFGIL 471
LLV N +G S ++ LFS FG L
Sbjct: 508 LLVKNFPYGTSAEELTSLFSPFGEL 532
>SPBC18H10.03 |tif35||translation initiation factor
eIF3g|Schizosaccharomyces pombe|chr 2|||Manual
Length = 282
Score = 31.9 bits (69), Expect = 0.073
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Frame = +1
Query: 397 LLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDR-SGRSLGTADVVFERRADALKAMKQY 573
L V+NL + ++++LF FG ++ + D+ +GR+ G A V + R A+KA +
Sbjct: 204 LRVTNLSDDTREEELRDLFRRFGGIQRVYLAKDKETGRAKGFAFVSYYDRDCAIKARDRL 263
Query: 574 NG 579
+G
Sbjct: 264 DG 265
>SPBC17G9.05 |rct1|cyp6|RRM-containing cyclophilin regulating
transcription Rct1|Schizosaccharomyces pombe|chr
2|||Manual
Length = 432
Score = 31.5 bits (68), Expect = 0.097
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Frame = +1
Query: 397 LLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDR-SGRSLGTADVVFERRADALKAMKQY 573
L V L+ D D++ +FS FG + S V D+ +G SL A + F+ + KA +
Sbjct: 246 LFVCKLNPVTQDEDLELIFSRFGKIISCQVIRDKETGDSLQYAFIEFDNKESVEKAYFKM 305
Query: 574 NGVPLD 591
V +D
Sbjct: 306 QNVLID 311
>SPBC4B4.07c |usp102|mud1|U1 snRNP-associated protein
Usp102|Schizosaccharomyces pombe|chr 2|||Manual
Length = 249
Score = 29.9 bits (64), Expect = 0.29
Identities = 18/52 (34%), Positives = 27/52 (51%)
Frame = +1
Query: 439 IQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADALKAMKQYNGVPLDG 594
++ LF +G K V ++ R G A VVF+ +A +A+K G PL G
Sbjct: 46 LEHLFGSYG--KVIDVQARKTLRMRGQAFVVFDNLENASRALKDLQGYPLYG 95
>SPAC23A1.09 |||RNA-binding protein|Schizosaccharomyces pombe|chr
1|||Manual
Length = 121
Score = 29.1 bits (62), Expect = 0.52
Identities = 17/66 (25%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Frame = +1
Query: 397 LLVSNLDFGVSDSDIQELFSEFGILKSAAVHYD-RSGRSLGTADVVFERRADALKAMKQY 573
++V+ + ++ +++LF++FG +K+ ++ D R+G G A + + A KA+ +
Sbjct: 12 IIVTGVHPEATEEQVEDLFADFGPVKNLHLNLDRRTGYVKGYALIEYATLEQAQKAVDEK 71
Query: 574 NGVPLD 591
N LD
Sbjct: 72 NLSLLD 77
>SPAC13G6.06c |||glycine cleavage complex subunit
P|Schizosaccharomyces pombe|chr 1|||Manual
Length = 1017
Score = 28.7 bits (61), Expect = 0.68
Identities = 15/28 (53%), Positives = 17/28 (60%)
Frame = +1
Query: 409 NLDFGVSDSDIQELFSEFGILKSAAVHY 492
+LD V D DIQ LFS F I KS +Y
Sbjct: 473 SLDETVCDKDIQALFSIFNINKSVDQYY 500
>SPBC29A10.02 |spo5|mrb1, mug12, SPBC365.18|meiotic RNA-binding
protein 1|Schizosaccharomyces pombe|chr 2|||Manual
Length = 567
Score = 28.3 bits (60), Expect = 0.90
Identities = 19/70 (27%), Positives = 31/70 (44%)
Frame = +1
Query: 382 TGPSKLLVSNLDFGVSDSDIQELFSEFGILKSAAVHYDRSGRSLGTADVVFERRADALKA 561
T + L +SNL ++SDI LF I+ + + D +S G + R A
Sbjct: 381 TESTNLYISNLPLHWNESDISTLFKPSKIISNRVLR-DSKEQSRGVGFARMQDRKTAEDI 439
Query: 562 MKQYNGVPLD 591
+ ++N LD
Sbjct: 440 INKFNNFVLD 449
>SPBC56F2.08c |||RNA-binding protein|Schizosaccharomyces pombe|chr
2|||Manual
Length = 661
Score = 27.9 bits (59), Expect = 1.2
Identities = 14/26 (53%), Positives = 16/26 (61%)
Frame = +1
Query: 397 LLVSNLDFGVSDSDIQELFSEFGILK 474
L VSNL G S S I LFS +G +K
Sbjct: 2 LYVSNLPVGTSSSAIHALFSAYGNVK 27
>SPAC3A11.14c |pkl1|klp1, SPAC3H5.03c|kinesin-like protein
Pkl1|Schizosaccharomyces pombe|chr 1|||Manual
Length = 832
Score = 27.1 bits (57), Expect = 2.1
Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 3/37 (8%)
Frame = -3
Query: 537 FKH---NICCT*RSSRSIIMNSCTLKNSKFREQFLNV 436
+KH NIC + R + +I SCT K +F+E+ L++
Sbjct: 291 YKHEYANICESLRRALVLIQGSCTEKILRFKEKILDL 327
>SPAC3F10.06c |||initiator methionine tRNA 2'-O-ribosyl phosphate
transferase |Schizosaccharomyces pombe|chr 1|||Manual
Length = 453
Score = 26.2 bits (55), Expect = 3.6
Identities = 11/30 (36%), Positives = 17/30 (56%)
Frame = -2
Query: 259 CLAILHLSGYYEIHHHVLVFCLYQIFCQHH 170
CLA++ L YY++H H+L + Q H
Sbjct: 381 CLALMILCLYYDLHMHLLAHPISLSASQSH 410
>SPACUNK4.16c |||alpha,alpha-trehalose-phosphate synthase
|Schizosaccharomyces pombe|chr 1|||Manual
Length = 944
Score = 26.2 bits (55), Expect = 3.6
Identities = 9/26 (34%), Positives = 16/26 (61%)
Frame = -3
Query: 384 CCDSTTSWNLPFTKIIEHVMFPCAVN 307
CC+S ++N+P + I++ M C N
Sbjct: 833 CCESVNNFNVPCSATIQNDMVVCRSN 858
>SPBC15D4.11c |||sequence orphan|Schizosaccharomyces pombe|chr
2|||Manual
Length = 263
Score = 25.8 bits (54), Expect = 4.8
Identities = 11/27 (40%), Positives = 16/27 (59%)
Frame = +2
Query: 317 HGNMTCSMILVKGRFQEVVLSQQVPQS 397
HG + C++IL KG +S Q PQ+
Sbjct: 149 HGTILCALILCKGMLHFDSISFQSPQN 175
>SPCC23B6.04c |||sec14 cytosolic factor family|Schizosaccharomyces
pombe|chr 3|||Manual
Length = 1008
Score = 25.0 bits (52), Expect = 8.4
Identities = 13/36 (36%), Positives = 18/36 (50%)
Frame = +1
Query: 400 LVSNLDFGVSDSDIQELFSEFGILKSAAVHYDRSGR 507
LV FGV++ D E+ E K + YD+ GR
Sbjct: 660 LVWRRHFGVNNMDPDEIQEENATGKQVLLGYDKDGR 695
Database: spombe
Posted date: Oct 4, 2007 10:57 AM
Number of letters in database: 2,362,478
Number of sequences in database: 5004
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 2,342,510
Number of Sequences: 5004
Number of extensions: 46313
Number of successful extensions: 132
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 131
length of database: 2,362,478
effective HSP length: 69
effective length of database: 2,017,202
effective search space used: 260219058
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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