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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= I10A02NGRL0001_J10
         (489 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X59498-1|CAA42087.1|  147|Homo sapiens transthyretin protein.          61   2e-09
U19780-1|AAA73473.1|  147|Homo sapiens transthyretin precursor p...    61   2e-09
M11844-1|AAA60013.1|  147|Homo sapiens protein ( Human prealbumi...    61   2e-09
M11518-1|AAA98771.1|  147|Homo sapiens prealbumin protein.             61   2e-09
M10605-1|AAA60012.1|  147|Homo sapiens prealbumin protein.             61   2e-09
K02091-1|AAA60011.1|  147|Homo sapiens TTR protein.                    61   2e-09
CR456908-1|CAG33189.1|  147|Homo sapiens TTR protein.                  61   2e-09
BT007189-1|AAP35853.1|  147|Homo sapiens transthyretin (prealbum...    61   2e-09
BC020791-1|AAH20791.1|  147|Homo sapiens transthyretin (prealbum...    61   2e-09
BC005310-1|AAH05310.1|  147|Homo sapiens transthyretin (prealbum...    61   2e-09
AF162690-1|AAD45014.1|  147|Homo sapiens transthyretin precursor...    61   2e-09
M11714-1|AAA61181.1|  117|Homo sapiens transthyretin protein.          61   2e-09
M15517-1|AAA60018.1|  147|Homo sapiens prealbumin protein.             60   4e-09
D00096-1|BAA00059.1|  147|Homo sapiens prealbumin protein.             60   4e-09
BC054492-1|AAH54492.1|  997|Homo sapiens RABGAP1 protein protein.      31   1.6  
AL365338-3|CAH70298.1|  997|Homo sapiens RAB GTPase activating p...    31   1.6  
AK131449-1|BAD18594.1|  599|Homo sapiens d) (GAPCENA).  protein.       31   1.6  
AJ011679-1|CAB40267.2|  997|Homo sapiens Rab6 GTPase activating ...    31   1.6  
AF161357-1|AAF28917.1|  308|Homo sapiens HSPC094 protein.              31   1.6  
BC011524-1|AAH11524.1|  356|Homo sapiens family with sequence si...    29   6.5  
AL512750-1|CAC21673.1|  118|Homo sapiens hypothetical protein pr...    29   6.5  
AK001989-1|BAA92023.1|  356|Homo sapiens protein ( Homo sapiens ...    29   6.5  

>X59498-1|CAA42087.1|  147|Homo sapiens transthyretin protein.
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>U19780-1|AAA73473.1|  147|Homo sapiens transthyretin precursor
           protein.
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>M11844-1|AAA60013.1|  147|Homo sapiens protein ( Human prealbumin
           gene, complete cds. ).
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>M11518-1|AAA98771.1|  147|Homo sapiens prealbumin protein.
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVPGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>M10605-1|AAA60012.1|  147|Homo sapiens prealbumin protein.
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>K02091-1|AAA60011.1|  147|Homo sapiens TTR protein.
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>CR456908-1|CAG33189.1|  147|Homo sapiens TTR protein.
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>BT007189-1|AAP35853.1|  147|Homo sapiens transthyretin (prealbumin,
           amyloidosis type I) protein.
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>BC020791-1|AAH20791.1|  147|Homo sapiens transthyretin (prealbumin,
           amyloidosis type I) protein.
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>BC005310-1|AAH05310.1|  147|Homo sapiens transthyretin (prealbumin,
           amyloidosis type I) protein.
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>AF162690-1|AAD45014.1|  147|Homo sapiens transthyretin precursor
           protein.
          Length = 147

 Score = 61.3 bits (142), Expect = 2e-09
 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>M11714-1|AAA61181.1|  117|Homo sapiens transthyretin protein.
          Length = 117

 Score = 60.9 bits (141), Expect = 2e-09
 Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 3/107 (2%)
 Frame = +3

Query: 30  LSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEGVYKL 206
           L   VLD   G PA+ + V +++K  D +W  + +  TS  G +    +++   EG+YK+
Sbjct: 2   LMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKV 61

Query: 207 KFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           + +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 62  EIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 108


>M15517-1|AAA60018.1|  147|Homo sapiens prealbumin protein.
          Length = 147

 Score = 60.1 bits (139), Expect = 4e-09
 Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + + +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>D00096-1|BAA00059.1|  147|Homo sapiens prealbumin protein.
          Length = 147

 Score = 60.1 bits (139), Expect = 4e-09
 Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
 Frame = +3

Query: 18  SRPVLSTHVLDISTGIPAVGLFVELYKKK-DTSWTLWHNTVTSGDGRIQFPFSKDSMAEG 194
           S+  L   VLD   G PA+ + + +++K  D +W  + +  TS  G +    +++   EG
Sbjct: 28  SKCPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG 87

Query: 195 VYKLKFNVSDYYKKTNTETLYPFVEITFHTKEGA--HYHIPLLLSPYGYST 341
           +YK++ +   Y+K       +   E+ F   +     Y I  LLSPY YST
Sbjct: 88  IYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYST 138


>BC054492-1|AAH54492.1|  997|Homo sapiens RABGAP1 protein protein.
          Length = 997

 Score = 31.5 bits (68), Expect = 1.6
 Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +3

Query: 135 VTSGDGRIQFPFSKDSMAEGVY-KLKFNVSDYYKKTNTETLYPFV 266
           V S + R+ +PFSK S  E  + KLK  +    +K NT+TLY  V
Sbjct: 360 VCSPNERLFWPFSKRSTTENFFLKLK-QIKQRERKNNTDTLYEVV 403


>AL365338-3|CAH70298.1|  997|Homo sapiens RAB GTPase activating
           protein 1 protein.
          Length = 997

 Score = 31.5 bits (68), Expect = 1.6
 Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +3

Query: 135 VTSGDGRIQFPFSKDSMAEGVY-KLKFNVSDYYKKTNTETLYPFV 266
           V S + R+ +PFSK S  E  + KLK  +    +K NT+TLY  V
Sbjct: 360 VCSPNERLFWPFSKRSTTENFFLKLK-QIKQRERKNNTDTLYEVV 403


>AK131449-1|BAD18594.1|  599|Homo sapiens d) (GAPCENA).  protein.
          Length = 599

 Score = 31.5 bits (68), Expect = 1.6
 Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +3

Query: 135 VTSGDGRIQFPFSKDSMAEGVY-KLKFNVSDYYKKTNTETLYPFV 266
           V S + R+ +PFSK S  E  + KLK  +    +K NT+TLY  V
Sbjct: 364 VCSPNERLFWPFSKRSTTENFFLKLK-QIKQRERKNNTDTLYEVV 407


>AJ011679-1|CAB40267.2|  997|Homo sapiens Rab6 GTPase activating
           protein, GAPCenA protein.
          Length = 997

 Score = 31.5 bits (68), Expect = 1.6
 Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +3

Query: 135 VTSGDGRIQFPFSKDSMAEGVY-KLKFNVSDYYKKTNTETLYPFV 266
           V S + R+ +PFSK S  E  + KLK  +    +K NT+TLY  V
Sbjct: 360 VCSPNERLFWPFSKRSTTENFFLKLK-QIKQRERKNNTDTLYEVV 403


>AF161357-1|AAF28917.1|  308|Homo sapiens HSPC094 protein.
          Length = 308

 Score = 31.5 bits (68), Expect = 1.6
 Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +3

Query: 135 VTSGDGRIQFPFSKDSMAEGVY-KLKFNVSDYYKKTNTETLYPFV 266
           V S + R+ +PFSK S  E  + KLK  +    +K NT+TLY  V
Sbjct: 261 VCSPNERLFWPFSKRSTTENFFLKLK-QIKQRERKNNTDTLYEVV 304


>BC011524-1|AAH11524.1|  356|Homo sapiens family with sequence
           similarity 105, member A protein.
          Length = 356

 Score = 29.5 bits (63), Expect = 6.5
 Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = +3

Query: 195 VYKL-KFNVSDYYKKTNTETLYPFVEITFHTKEGAHYHIPL 314
           V++L KFN  D+      E L  + EI+  T+   HYHIP+
Sbjct: 315 VFRLFKFNSRDFEVCYPEEPLRDWPEISLLTENDRHYHIPV 355


>AL512750-1|CAC21673.1|  118|Homo sapiens hypothetical protein
           protein.
          Length = 118

 Score = 29.5 bits (63), Expect = 6.5
 Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = +3

Query: 195 VYKL-KFNVSDYYKKTNTETLYPFVEITFHTKEGAHYHIPL 314
           V++L KFN  D+      E L  + EI+  T+   HYHIP+
Sbjct: 77  VFRLFKFNSRDFEVCYPEEPLRDWPEISLLTENDRHYHIPV 117


>AK001989-1|BAA92023.1|  356|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11127 fis, clone PLACE1006225. ).
          Length = 356

 Score = 29.5 bits (63), Expect = 6.5
 Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = +3

Query: 195 VYKL-KFNVSDYYKKTNTETLYPFVEITFHTKEGAHYHIPL 314
           V++L KFN  D+      E L  + EI+  T+   HYHIP+
Sbjct: 315 VFRLFKFNSRDFEVCYPEEPLRDWPEISLLTENDRHYHIPV 355


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 74,628,155
Number of Sequences: 237096
Number of extensions: 1550621
Number of successful extensions: 6327
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 6241
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6299
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4366354454
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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