Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0001_H19
(643 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P25782 Cluster: Digestive cysteine proteinase 2 precurs... 51 3e-05
UniRef50_A5HJW4 Cluster: Cathepsin L; n=3; Coelomata|Rep: Cathep... 48 3e-04
UniRef50_P07711 Cluster: Cathepsin L precursor (EC 3.4.22.15) (M... 48 3e-04
UniRef50_Q3YPH2 Cluster: Cathepsin L-like cysteine proteinase; n... 47 4e-04
UniRef50_O02586 Cluster: Cysteine proteinase; n=3; Spirometra er... 47 4e-04
UniRef50_Q26636 Cluster: Cathepsin L precursor (EC 3.4.22.15) [C... 46 6e-04
UniRef50_Q8WQZ8 Cluster: Cysteine proteinase; n=2; Acanthamoeba|... 46 0.001
UniRef50_A2I407 Cluster: Putative cathepsin L-like cysteine prot... 46 0.001
UniRef50_O60911 Cluster: Cathepsin L2 precursor; n=42; Coelomata... 45 0.001
UniRef50_UPI00015B62BC Cluster: PREDICTED: similar to cathepsin ... 45 0.002
UniRef50_O18456 Cluster: Cathepsin S-like cysteine proteinase pr... 45 0.002
UniRef50_O96086 Cluster: Cathepsin L-like tick cysteine proteina... 44 0.002
UniRef50_UPI0000E224BB Cluster: PREDICTED: hypothetical protein;... 44 0.003
UniRef50_Q6A1I0 Cluster: Cathepsin L; n=3; Metazoa|Rep: Cathepsi... 44 0.003
UniRef50_UPI0000501FDB Cluster: UPI0000501FDB related cluster; n... 44 0.004
UniRef50_UPI0000D566EF Cluster: PREDICTED: similar to cathepsin ... 43 0.005
UniRef50_UPI0000D55A76 Cluster: PREDICTED: similar to Cathepsin ... 43 0.005
UniRef50_P25774 Cluster: Cathepsin S precursor; n=78; Euteleosto... 43 0.005
UniRef50_Q80UB0 Cluster: Testin-2 precursor [Contains: Testin-1]... 42 0.010
UniRef50_Q24940 Cluster: Cathepsin L-like proteinase precursor; ... 42 0.010
UniRef50_Q9JIA9 Cluster: Cathepsin R precursor; n=30; Muridae|Re... 42 0.013
UniRef50_Q568D6 Cluster: Cathepsin K; n=13; Euteleostomi|Rep: Ca... 41 0.022
UniRef50_Q3ZCX6 Cluster: Cathepsin L-like cysteine proteinase; n... 41 0.022
UniRef50_A4KBK6 Cluster: Cathepsin L-like cysteine protease; n=3... 41 0.022
UniRef50_Q4TI44 Cluster: Chromosome undetermined SCAF2412, whole... 41 0.029
UniRef50_Q5DAH1 Cluster: SJCHGC06231 protein; n=1; Schistosoma j... 41 0.029
UniRef50_Q0PZI3 Cluster: Cathepsin L 2; n=1; Diaprepes abbreviat... 41 0.029
UniRef50_Q69G21 Cluster: Cathepsin L-like protein; n=2; Tenebrio... 40 0.039
UniRef50_Q5BL90 Cluster: LOC594890 protein; n=9; Xenopus tropica... 40 0.051
UniRef50_Q70EW9 Cluster: Cathepsin L-like proteinase precursor; ... 40 0.067
UniRef50_Q1MTY8 Cluster: Silicatein a3; n=15; root|Rep: Silicate... 40 0.067
UniRef50_Q0WYD8 Cluster: Cathepsin L-like proteinase; n=2; Platy... 39 0.089
UniRef50_UPI0000E46171 Cluster: PREDICTED: hypothetical protein;... 39 0.12
UniRef50_Q2M437 Cluster: Cathepsin-like cysteine protease; n=1; ... 39 0.12
UniRef50_A2GD33 Cluster: Clan CA, family C1, cathepsin L-like cy... 39 0.12
UniRef50_P04989 Cluster: Cysteine proteinase 2 precursor; n=2; D... 39 0.12
UniRef50_O17473 Cluster: Cathepsin L-like precursor; n=9; Onchoc... 39 0.12
UniRef50_Q9XY38 Cluster: Cysteine proteinase; n=1; Acanthamoeba ... 38 0.16
UniRef50_Q5BTK3 Cluster: SJCHGC00358 protein; n=1; Schistosoma j... 38 0.16
UniRef50_UPI0001554DAA Cluster: PREDICTED: similar to ferritin h... 38 0.21
UniRef50_UPI0000E492F4 Cluster: PREDICTED: similar to cathepsin ... 38 0.21
UniRef50_Q9VNK6 Cluster: CG11459-PA; n=1; Drosophila melanogaste... 38 0.21
UniRef50_Q70TB1 Cluster: Silicatein beta; n=3; Demospongiae|Rep:... 38 0.21
UniRef50_Q54TR1 Cluster: Counting factor associated protein; n=1... 38 0.21
UniRef50_Q27645 Cluster: Cysteine proteinase; n=7; Entamoeba|Rep... 38 0.21
UniRef50_Q967D5 Cluster: Cathepsin; n=1; Geodia cydonium|Rep: Ca... 38 0.27
UniRef50_Q7SXQ7 Cluster: Cathepsin; n=1; Petromyzon marinus|Rep:... 37 0.36
UniRef50_Q75PZ5 Cluster: Cahepsin L-like cysteine protease; n=2;... 37 0.36
UniRef50_A4VEB9 Cluster: Putative uncharacterized protein; n=1; ... 37 0.48
UniRef50_A3EXS2 Cluster: Cathepsin L-like cysteine proteinase-li... 36 0.63
UniRef50_Q1LUB5 Cluster: Novel protein similar to vertebrate cat... 36 0.83
UniRef50_A1VZU0 Cluster: Cation efflux family protein; n=12; Cam... 36 0.83
UniRef50_UPI0000F2B3F1 Cluster: PREDICTED: similar to cathepsin ... 36 1.1
UniRef50_Q7YXL2 Cluster: Cathepsin-L-like midgut cysteine protei... 36 1.1
UniRef50_Q2FUP2 Cluster: Uncharacterized membrane protein requir... 36 1.1
UniRef50_A2F139 Cluster: Clan CA, family C1, cathepsin L-like cy... 35 1.5
UniRef50_Q6QRP7 Cluster: Digestive cysteine proteinase intestain... 35 1.9
UniRef50_Q4C5V5 Cluster: Protein kinase; n=1; Crocosphaera watso... 33 4.4
UniRef50_Q6R3Q1 Cluster: Cathepsin L-like cysteine proteinase; n... 33 4.4
UniRef50_A2E346 Cluster: Clan CA, family C1, cathepsin L-like cy... 33 4.4
UniRef50_Q9BJX3 Cluster: Putative ATPase; n=1; Trypanosoma cruzi... 33 5.9
UniRef50_UPI0000E4A202 Cluster: PREDICTED: similar to Transmembr... 33 7.7
UniRef50_A4Y8H0 Cluster: Putative uncharacterized protein; n=1; ... 33 7.7
UniRef50_Q09FA3 Cluster: Heme maturase; n=2; Tetrahymena|Rep: He... 33 7.7
UniRef50_Q8H166 Cluster: Thiol protease aleurain precursor; n=18... 33 7.7
>UniRef50_P25782 Cluster: Digestive cysteine proteinase 2 precursor;
n=3; Metazoa|Rep: Digestive cysteine proteinase 2
precursor - Homarus americanus (American lobster)
Length = 323
Score = 50.8 bits (116), Expect = 3e-05
Identities = 21/26 (80%), Positives = 24/26 (92%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYPLV 80
D GYIKM+RNRNN+CGIA+ ASYPLV
Sbjct: 298 DAGYIKMSRNRNNNCGIATVASYPLV 323
>UniRef50_A5HJW4 Cluster: Cathepsin L; n=3; Coelomata|Rep: Cathepsin
L - Misgurnus mizolepis (Mud loach)
Length = 337
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/26 (76%), Positives = 23/26 (88%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYPLV 80
D GYI MA++R NHCGIA+AASYPLV
Sbjct: 312 DKGYIYMAKDRKNHCGIATAASYPLV 337
>UniRef50_P07711 Cluster: Cathepsin L precursor (EC 3.4.22.15)
(Major excreted protein) (MEP) [Contains: Cathepsin L
heavy chain; Cathepsin L light chain]; n=19;
Eukaryota|Rep: Cathepsin L precursor (EC 3.4.22.15)
(Major excreted protein) (MEP) [Contains: Cathepsin L
heavy chain; Cathepsin L light chain] - Homo sapiens
(Human)
Length = 333
Score = 47.6 bits (108), Expect = 3e-04
Identities = 19/24 (79%), Positives = 22/24 (91%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY+KMA++R NHCGIASAASYP V
Sbjct: 310 GYVKMAKDRRNHCGIASAASYPTV 333
>UniRef50_Q3YPH2 Cluster: Cathepsin L-like cysteine proteinase;
n=21; Bilateria|Rep: Cathepsin L-like cysteine
proteinase - Globodera pallida
Length = 379
Score = 46.8 bits (106), Expect = 4e-04
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI+MARNR N+CGIAS ASYPLV
Sbjct: 356 GYIRMARNRKNNCGIASHASYPLV 379
>UniRef50_O02586 Cluster: Cysteine proteinase; n=3; Spirometra
erinaceieuropaei|Rep: Cysteine proteinase - Spirometra
erinaceieuropaei (Tapeworm)
Length = 336
Score = 46.8 bits (106), Expect = 4e-04
Identities = 20/24 (83%), Positives = 21/24 (87%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY+KMARNRNN CGIAS ASYP V
Sbjct: 313 GYLKMARNRNNMCGIASMASYPTV 336
>UniRef50_Q26636 Cluster: Cathepsin L precursor (EC 3.4.22.15)
[Contains: Cathepsin L heavy chain; Cathepsin L light
chain]; n=71; Coelomata|Rep: Cathepsin L precursor (EC
3.4.22.15) [Contains: Cathepsin L heavy chain; Cathepsin
L light chain] - Sarcophaga peregrina (Flesh fly)
(Boettcherisca peregrina)
Length = 339
Score = 46.4 bits (105), Expect = 6e-04
Identities = 19/24 (79%), Positives = 22/24 (91%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYIKMARN+NN CGIA+A+SYP V
Sbjct: 316 GYIKMARNQNNQCGIATASSYPTV 339
>UniRef50_Q8WQZ8 Cluster: Cysteine proteinase; n=2;
Acanthamoeba|Rep: Cysteine proteinase - Acanthamoeba
healyi
Length = 330
Score = 45.6 bits (103), Expect = 0.001
Identities = 18/22 (81%), Positives = 22/22 (100%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYP 74
GYIKM+RN+NN+CGIA+AASYP
Sbjct: 307 GYIKMSRNQNNNCGIATAASYP 328
>UniRef50_A2I407 Cluster: Putative cathepsin L-like cysteine
protease; n=1; Maconellicoccus hirsutus|Rep: Putative
cathepsin L-like cysteine protease - Maconellicoccus
hirsutus (hibiscus mealybug)
Length = 339
Score = 45.6 bits (103), Expect = 0.001
Identities = 17/24 (70%), Positives = 23/24 (95%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI+MARN+NNHCGIA++AS P++
Sbjct: 316 GYIRMARNKNNHCGIATSASVPML 339
>UniRef50_O60911 Cluster: Cathepsin L2 precursor; n=42;
Coelomata|Rep: Cathepsin L2 precursor - Homo sapiens
(Human)
Length = 334
Score = 45.2 bits (102), Expect = 0.001
Identities = 17/24 (70%), Positives = 23/24 (95%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY+K+A+++NNHCGIA+AASYP V
Sbjct: 311 GYVKIAKDKNNHCGIATAASYPNV 334
>UniRef50_UPI00015B62BC Cluster: PREDICTED: similar to cathepsin
L-like protease; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to cathepsin L-like protease -
Nasonia vitripennis
Length = 353
Score = 44.8 bits (101), Expect = 0.002
Identities = 17/24 (70%), Positives = 21/24 (87%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY K+ARNR NHCGIA+AA YP++
Sbjct: 330 GYFKVARNRRNHCGIAAAAVYPVI 353
>UniRef50_O18456 Cluster: Cathepsin S-like cysteine proteinase
precursor; n=2; Bilateria|Rep: Cathepsin S-like cysteine
proteinase precursor - Heterodera glycines (Soybean cyst
nematode worm)
Length = 353
Score = 44.8 bits (101), Expect = 0.002
Identities = 17/24 (70%), Positives = 22/24 (91%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI++ARN+ NHCGIA+ ASYP+V
Sbjct: 330 GYIRIARNKQNHCGIATMASYPVV 353
>UniRef50_O96086 Cluster: Cathepsin L-like tick cysteine proteinase
B; n=1; Haemaphysalis longicornis|Rep: Cathepsin L-like
tick cysteine proteinase B - Haemaphysalis longicornis
(Bush tick)
Length = 332
Score = 44.4 bits (100), Expect = 0.002
Identities = 19/26 (73%), Positives = 22/26 (84%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYPLV 80
D GYI M RN++N CGIAS+ASYPLV
Sbjct: 307 DEGYIYMTRNQDNQCGIASSASYPLV 332
>UniRef50_UPI0000E224BB Cluster: PREDICTED: hypothetical protein;
n=1; Pan troglodytes|Rep: PREDICTED: hypothetical
protein - Pan troglodytes
Length = 143
Score = 44.0 bits (99), Expect = 0.003
Identities = 18/24 (75%), Positives = 22/24 (91%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYIKMA++R N+CGIA+AASYP V
Sbjct: 120 GYIKMAKDRRNNCGIATAASYPTV 143
>UniRef50_Q6A1I0 Cluster: Cathepsin L; n=3; Metazoa|Rep: Cathepsin L
- Suberites domuncula (Sponge)
Length = 324
Score = 44.0 bits (99), Expect = 0.003
Identities = 18/24 (75%), Positives = 21/24 (87%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI M+RNR N+CGIAS ASYP+V
Sbjct: 301 GYIMMSRNRRNNCGIASQASYPIV 324
>UniRef50_UPI0000501FDB Cluster: UPI0000501FDB related cluster; n=1;
Rattus norvegicus|Rep: UPI0000501FDB UniRef100 entry -
Rattus norvegicus
Length = 338
Score = 43.6 bits (98), Expect = 0.004
Identities = 16/24 (66%), Positives = 22/24 (91%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY+K+A++RNNHCGIA+ A YP+V
Sbjct: 315 GYMKIAKDRNNHCGIATFAQYPIV 338
>UniRef50_UPI0000D566EF Cluster: PREDICTED: similar to cathepsin S
preproprotein; n=2; Tribolium castaneum|Rep: PREDICTED:
similar to cathepsin S preproprotein - Tribolium
castaneum
Length = 525
Score = 43.2 bits (97), Expect = 0.005
Identities = 15/23 (65%), Positives = 20/23 (86%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPL 77
GY+K+ARNRNNHCGI + +YP+
Sbjct: 501 GYVKIARNRNNHCGITNRITYPI 523
>UniRef50_UPI0000D55A76 Cluster: PREDICTED: similar to Cathepsin K
precursor (Cathepsin O) (Cathepsin X) (Cathepsin O2);
n=2; Tribolium castaneum|Rep: PREDICTED: similar to
Cathepsin K precursor (Cathepsin O) (Cathepsin X)
(Cathepsin O2) - Tribolium castaneum
Length = 332
Score = 43.2 bits (97), Expect = 0.005
Identities = 17/23 (73%), Positives = 20/23 (86%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPL 77
GY+KMARNR N CGIA+ ASYP+
Sbjct: 309 GYVKMARNRRNQCGIATHASYPV 331
>UniRef50_P25774 Cluster: Cathepsin S precursor; n=78;
Euteleostomi|Rep: Cathepsin S precursor - Homo sapiens
(Human)
Length = 331
Score = 43.2 bits (97), Expect = 0.005
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYP 74
GYI+MARN+ NHCGIAS SYP
Sbjct: 308 GYIRMARNKGNHCGIASFPSYP 329
>UniRef50_Q80UB0 Cluster: Testin-2 precursor [Contains: Testin-1];
n=11; Eutheria|Rep: Testin-2 precursor [Contains:
Testin-1] - Mus musculus (Mouse)
Length = 333
Score = 42.3 bits (95), Expect = 0.010
Identities = 16/24 (66%), Positives = 22/24 (91%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYIK+A++ NNHCGIA+ A+YP+V
Sbjct: 310 GYIKIAKDWNNHCGIATLATYPIV 333
>UniRef50_Q24940 Cluster: Cathepsin L-like proteinase precursor;
n=35; Fasciola|Rep: Cathepsin L-like proteinase
precursor - Fasciola hepatica (Liver fluke)
Length = 326
Score = 42.3 bits (95), Expect = 0.010
Identities = 19/26 (73%), Positives = 21/26 (80%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV*R 86
GYI+MARNR N CGIAS AS P+V R
Sbjct: 299 GYIRMARNRGNMCGIASLASLPMVAR 324
>UniRef50_Q9JIA9 Cluster: Cathepsin R precursor; n=30; Muridae|Rep:
Cathepsin R precursor - Mus musculus (Mouse)
Length = 334
Score = 41.9 bits (94), Expect = 0.013
Identities = 15/24 (62%), Positives = 21/24 (87%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY+K+A+++NNHCGIAS A YP +
Sbjct: 311 GYMKLAKDKNNHCGIASYAHYPTI 334
>UniRef50_Q568D6 Cluster: Cathepsin K; n=13; Euteleostomi|Rep:
Cathepsin K - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 333
Score = 41.1 bits (92), Expect = 0.022
Identities = 16/24 (66%), Positives = 21/24 (87%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY+ MARNRNN CGIA+ AS+P++
Sbjct: 310 GYVLMARNRNNACGIANLASFPVM 333
>UniRef50_Q3ZCX6 Cluster: Cathepsin L-like cysteine proteinase; n=3;
Bilateria|Rep: Cathepsin L-like cysteine proteinase -
Longidorus elongatus
Length = 358
Score = 41.1 bits (92), Expect = 0.022
Identities = 17/26 (65%), Positives = 21/26 (80%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYPLV 80
D GYI M+R +NN+CGIA+ ASYP V
Sbjct: 331 DDGYILMSRRKNNNCGIATMASYPFV 356
>UniRef50_A4KBK6 Cluster: Cathepsin L-like cysteine protease; n=3;
Bilateria|Rep: Cathepsin L-like cysteine protease -
Neobenedenia melleni
Length = 335
Score = 41.1 bits (92), Expect = 0.022
Identities = 15/24 (62%), Positives = 21/24 (87%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI M+RN++N CG+A+ ASYP+V
Sbjct: 312 GYILMSRNKDNQCGVATVASYPIV 335
>UniRef50_Q4TI44 Cluster: Chromosome undetermined SCAF2412, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF2412,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 123
Score = 40.7 bits (91), Expect = 0.029
Identities = 17/24 (70%), Positives = 20/24 (83%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI MARNR N CGIA+ ASYP++
Sbjct: 100 GYILMARNRGNLCGIANLASYPIM 123
>UniRef50_Q5DAH1 Cluster: SJCHGC06231 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06231 protein - Schistosoma
japonicum (Blood fluke)
Length = 372
Score = 40.7 bits (91), Expect = 0.029
Identities = 16/26 (61%), Positives = 21/26 (80%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYPLV 80
D GY+K+ ++ N CG+ASAASYPLV
Sbjct: 347 DKGYVKILKDSKNMCGVASAASYPLV 372
>UniRef50_Q0PZI3 Cluster: Cathepsin L 2; n=1; Diaprepes
abbreviatus|Rep: Cathepsin L 2 - Diaprepes abbreviatus
(Sugarcane rootstalk borer weevil)
Length = 348
Score = 40.7 bits (91), Expect = 0.029
Identities = 16/24 (66%), Positives = 20/24 (83%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYP 74
D GYI+MA+++NN CGIA ASYP
Sbjct: 323 DQGYIRMAKDKNNQCGIALMASYP 346
>UniRef50_Q69G21 Cluster: Cathepsin L-like protein; n=2;
Tenebrionidae|Rep: Cathepsin L-like protein - Tenebrio
molitor (Yellow mealworm)
Length = 336
Score = 40.3 bits (90), Expect = 0.039
Identities = 16/22 (72%), Positives = 17/22 (77%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYP 74
GY K+ARN NNHCGIA AS P
Sbjct: 313 GYFKIARNANNHCGIAGVASVP 334
>UniRef50_Q5BL90 Cluster: LOC594890 protein; n=9; Xenopus
tropicalis|Rep: LOC594890 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 355
Score = 39.9 bits (89), Expect = 0.051
Identities = 16/26 (61%), Positives = 21/26 (80%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYPLV 80
D GYIKMARN +N+CGIA+ +P+V
Sbjct: 330 DEGYIKMARNHHNNCGIANFGCFPVV 355
>UniRef50_Q70EW9 Cluster: Cathepsin L-like proteinase precursor;
n=6; Chrysomelidae|Rep: Cathepsin L-like proteinase
precursor - Diabrotica virgifera virgifera (western corn
rootworm)
Length = 326
Score = 39.5 bits (88), Expect = 0.067
Identities = 15/24 (62%), Positives = 20/24 (83%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI M+RN+NN CGIA+ A+YP +
Sbjct: 303 GYIWMSRNKNNQCGIATDATYPTI 326
>UniRef50_Q1MTY8 Cluster: Silicatein a3; n=15; root|Rep: Silicatein
a3 - Lubomirskia baicalensis
Length = 344
Score = 39.5 bits (88), Expect = 0.067
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYIKM RN+ N CGIAS A YP++
Sbjct: 321 GYIKMVRNKYNQCGIASDALYPML 344
>UniRef50_Q0WYD8 Cluster: Cathepsin L-like proteinase; n=2;
Platyhelminthes|Rep: Cathepsin L-like proteinase -
Echinococcus multilocularis
Length = 338
Score = 39.1 bits (87), Expect = 0.089
Identities = 16/24 (66%), Positives = 20/24 (83%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI MAR++ N CGIA+ ASYPL+
Sbjct: 315 GYIWMARDKGNMCGIATMASYPLI 338
>UniRef50_UPI0000E46171 Cluster: PREDICTED: hypothetical protein;
n=4; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 892
Score = 38.7 bits (86), Expect = 0.12
Identities = 16/22 (72%), Positives = 18/22 (81%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYP 74
GYI +ARNRNN CGIA+ A YP
Sbjct: 868 GYINIARNRNNMCGIATDAIYP 889
>UniRef50_Q2M437 Cluster: Cathepsin-like cysteine protease; n=1;
Phytophthora infestans|Rep: Cathepsin-like cysteine
protease - Phytophthora infestans (Potato late blight
fungus)
Length = 376
Score = 38.7 bits (86), Expect = 0.12
Identities = 14/24 (58%), Positives = 21/24 (87%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI M+RN++N CGIA+ A+YP++
Sbjct: 331 GYIMMSRNKDNQCGIATDATYPIM 354
>UniRef50_A2GD33 Cluster: Clan CA, family C1, cathepsin L-like
cysteine peptidase; n=2; Trichomonas vaginalis G3|Rep:
Clan CA, family C1, cathepsin L-like cysteine peptidase
- Trichomonas vaginalis G3
Length = 234
Score = 38.7 bits (86), Expect = 0.12
Identities = 15/24 (62%), Positives = 20/24 (83%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYIKM+RN++N CGIA+ A PL+
Sbjct: 210 GYIKMSRNKDNQCGIATEAVIPLI 233
>UniRef50_P04989 Cluster: Cysteine proteinase 2 precursor; n=2;
Dictyostelium discoideum|Rep: Cysteine proteinase 2
precursor - Dictyostelium discoideum (Slime mold)
Length = 376
Score = 38.7 bits (86), Expect = 0.12
Identities = 15/23 (65%), Positives = 20/23 (86%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPL 77
GYI M+++R N+CGIAS +SYPL
Sbjct: 353 GYILMSKDRKNNCGIASVSSYPL 375
>UniRef50_O17473 Cluster: Cathepsin L-like precursor; n=9;
Onchocercidae|Rep: Cathepsin L-like precursor - Brugia
pahangi (Filarial nematode worm)
Length = 395
Score = 38.7 bits (86), Expect = 0.12
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPL 77
GY+ MARNR N C IASAAS+P+
Sbjct: 373 GYVYMARNRGNMCHIASAASFPI 395
>UniRef50_Q9XY38 Cluster: Cysteine proteinase; n=1; Acanthamoeba
culbertsoni|Rep: Cysteine proteinase - Acanthamoeba
culbertsoni
Length = 482
Score = 38.3 bits (85), Expect = 0.16
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYP 74
D GY+ MARN+NN+CGIAS A P
Sbjct: 348 DDGYVYMARNKNNNCGIASLAVLP 371
>UniRef50_Q5BTK3 Cluster: SJCHGC00358 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC00358 protein - Schistosoma
japonicum (Blood fluke)
Length = 78
Score = 38.3 bits (85), Expect = 0.16
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYPLV 80
D GYIK+ARN +N C IAS A YP++
Sbjct: 53 DQGYIKLARNHSNMCHIASYAYYPVI 78
>UniRef50_UPI0001554DAA Cluster: PREDICTED: similar to ferritin
heavy chain; n=3; Amniota|Rep: PREDICTED: similar to
ferritin heavy chain - Ornithorhynchus anatinus
Length = 338
Score = 37.9 bits (84), Expect = 0.21
Identities = 12/24 (50%), Positives = 20/24 (83%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY+++ + NNHCG+AS AS+P++
Sbjct: 315 GYMRLLKGANNHCGVASVASFPVL 338
>UniRef50_UPI0000E492F4 Cluster: PREDICTED: similar to cathepsin
L-like proteinase; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to cathepsin L-like
proteinase - Strongylocentrotus purpuratus
Length = 329
Score = 37.9 bits (84), Expect = 0.21
Identities = 16/24 (66%), Positives = 18/24 (75%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYP 74
D GYI +ARN NN CGIA+ A YP
Sbjct: 303 DNGYINIARNHNNMCGIATDAIYP 326
>UniRef50_Q9VNK6 Cluster: CG11459-PA; n=1; Drosophila
melanogaster|Rep: CG11459-PA - Drosophila melanogaster
(Fruit fly)
Length = 336
Score = 37.9 bits (84), Expect = 0.21
Identities = 14/22 (63%), Positives = 17/22 (77%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYP 74
GY+K+ARN NN CG+AS YP
Sbjct: 313 GYLKLARNANNMCGVASLPQYP 334
>UniRef50_Q70TB1 Cluster: Silicatein beta; n=3; Demospongiae|Rep:
Silicatein beta - Suberites domuncula (Sponge)
Length = 383
Score = 37.9 bits (84), Expect = 0.21
Identities = 15/22 (68%), Positives = 19/22 (86%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYP 74
GY K+ARN+ N CGIA+AAS+P
Sbjct: 360 GYGKLARNKGNKCGIATAASFP 381
>UniRef50_Q54TR1 Cluster: Counting factor associated protein; n=1;
Dictyostelium discoideum AX4|Rep: Counting factor
associated protein - Dictyostelium discoideum AX4
Length = 531
Score = 37.9 bits (84), Expect = 0.21
Identities = 14/23 (60%), Positives = 19/23 (82%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPL 77
GY+ MARN NN CG++S A+YP+
Sbjct: 505 GYVYMARNDNNLCGVSSQATYPI 527
>UniRef50_Q27645 Cluster: Cysteine proteinase; n=7; Entamoeba|Rep:
Cysteine proteinase - Entamoeba histolytica
Length = 320
Score = 37.9 bits (84), Expect = 0.21
Identities = 15/22 (68%), Positives = 18/22 (81%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYP 74
GYI M+RN+NN CGIA+ A YP
Sbjct: 291 GYILMSRNKNNQCGIANDAIYP 312
>UniRef50_Q967D5 Cluster: Cathepsin; n=1; Geodia cydonium|Rep:
Cathepsin - Geodia cydonium (Sponge)
Length = 322
Score = 37.5 bits (83), Expect = 0.27
Identities = 15/24 (62%), Positives = 21/24 (87%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
G + M+RNR+N+CGIA+ ASYP+V
Sbjct: 296 GDMMMSRNRDNNCGIATMASYPVV 319
>UniRef50_Q7SXQ7 Cluster: Cathepsin; n=1; Petromyzon marinus|Rep:
Cathepsin - Petromyzon marinus (Sea lamprey)
Length = 333
Score = 37.1 bits (82), Expect = 0.36
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI M RN++N CGIAS YP++
Sbjct: 310 GYIYMIRNKDNQCGIASIGIYPII 333
>UniRef50_Q75PZ5 Cluster: Cahepsin L-like cysteine protease; n=2;
Brugia malayi|Rep: Cahepsin L-like cysteine protease -
Brugia malayi (Filarial nematode worm)
Length = 371
Score = 37.1 bits (82), Expect = 0.36
Identities = 15/24 (62%), Positives = 18/24 (75%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY+K+ARN+ N CGI A YPLV
Sbjct: 343 GYLKLARNQENMCGIGFYACYPLV 366
>UniRef50_A4VEB9 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 175
Score = 36.7 bits (81), Expect = 0.48
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
Frame = -2
Query: 399 LFNFIKNICKCVITSSIRYDSLFKI*QL--TLGAVILLTFIYLRDVIIFFSLLLFCNYFF 226
LFN K IC+ SI ++ I L L +ILL F++ + FF +L C +F
Sbjct: 36 LFNLKKIICRQFYFKSIYECIIYNIIYLFFQLKCLILLAFLFQNKINGFFIFILICGFFV 95
Query: 225 LILFRIPDVK-YNVYV 181
L F+ +K +N ++
Sbjct: 96 LFYFKSSCLKGFNTFL 111
>UniRef50_A3EXS2 Cluster: Cathepsin L-like cysteine proteinase-like
protein; n=1; Maconellicoccus hirsutus|Rep: Cathepsin
L-like cysteine proteinase-like protein -
Maconellicoccus hirsutus (hibiscus mealybug)
Length = 253
Score = 36.3 bits (80), Expect = 0.63
Identities = 14/24 (58%), Positives = 19/24 (79%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY+++ARNRNN CGIA YP++
Sbjct: 229 GYMRLARNRNNLCGIAHIFYYPVL 252
>UniRef50_Q1LUB5 Cluster: Novel protein similar to vertebrate
cathepsin L; n=4; Danio rerio|Rep: Novel protein similar
to vertebrate cathepsin L - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 334
Score = 35.9 bits (79), Expect = 0.83
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY++M RN N CGIAS A YP++
Sbjct: 311 GYMRMIRNGKNTCGIASYALYPII 334
>UniRef50_A1VZU0 Cluster: Cation efflux family protein; n=12;
Campylobacter|Rep: Cation efflux family protein -
Campylobacter jejuni subsp. jejuni serotype O:23/36
(strain 81-176)
Length = 295
Score = 35.9 bits (79), Expect = 0.83
Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 7/92 (7%)
Frame = -2
Query: 498 FIFYSSKLKITY----KDKGICFHF*NSVLII*DFLVLF-NFIKNICKCVITSS--IRYD 340
FIFY S LKI Y KD + LI+ FLVLF N++ K +I S + Y
Sbjct: 91 FIFYESILKIYYKEEIKDLNSSIYVMIFALIMTFFLVLFLNYVAKKTKSLIIESDALHYK 150
Query: 339 SLFKI*QLTLGAVILLTFIYLRDVIIFFSLLL 244
+ TLGA++L+ F L + F +++
Sbjct: 151 TDCLTNACTLGALVLIYFTNLHIIDAIFGIVI 182
>UniRef50_UPI0000F2B3F1 Cluster: PREDICTED: similar to cathepsin L
preproprotein; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to cathepsin L preproprotein -
Monodelphis domestica
Length = 356
Score = 35.5 bits (78), Expect = 1.1
Identities = 14/26 (53%), Positives = 20/26 (76%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYPLV 80
D GYI + ++R N CGIAS A+YP++
Sbjct: 331 DRGYIYIPKDRYNQCGIASNANYPIL 356
>UniRef50_Q7YXL2 Cluster: Cathepsin-L-like midgut cysteine
proteinase; n=4; Tenebrio molitor|Rep: Cathepsin-L-like
midgut cysteine proteinase - Tenebrio molitor (Yellow
mealworm)
Length = 330
Score = 35.5 bits (78), Expect = 1.1
Identities = 14/22 (63%), Positives = 17/22 (77%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYP 74
GY + RN N+CGIA+AASYP
Sbjct: 307 GYWRQVRNYGNNCGIATAASYP 328
>UniRef50_Q2FUP2 Cluster: Uncharacterized membrane protein required
for N-linked glycosylation- like precursor; n=1;
Methanospirillum hungatei JF-1|Rep: Uncharacterized
membrane protein required for N-linked glycosylation-
like precursor - Methanospirillum hungatei (strain JF-1
/ DSM 864)
Length = 808
Score = 35.5 bits (78), Expect = 1.1
Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Frame = -2
Query: 405 LVLFNFIKNICKCVITSSIRYDSLFKI*QLTLGAVILLTFIYLRDVIIF-FSLLLFCNYF 229
++LF I + +IT +++S L G V +LT I +R I+F L L YF
Sbjct: 369 VMLFLLIPALILLLITGIRKHNSNIVYLLLWTGFVGVLTIINIRFEILFAVPLTLTSAYF 428
Query: 228 FLILFRIPDVKYNVYVN*ESDQSSRKRYVNMRNR 127
LF D + +Y N ES Q+S + +N + R
Sbjct: 429 LDWLFHFNDQRTEIY-NEESCQNSTYKIINWKKR 461
>UniRef50_A2F139 Cluster: Clan CA, family C1, cathepsin L-like
cysteine peptidase; n=2; Trichomonas vaginalis G3|Rep:
Clan CA, family C1, cathepsin L-like cysteine peptidase
- Trichomonas vaginalis G3
Length = 291
Score = 35.1 bits (77), Expect = 1.5
Identities = 12/23 (52%), Positives = 20/23 (86%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPL 77
GY+++A+++NN CG+A+ AS PL
Sbjct: 267 GYMRLAKDKNNMCGVATMASIPL 289
>UniRef50_Q6QRP7 Cluster: Digestive cysteine proteinase intestain;
n=9; Cucujiformia|Rep: Digestive cysteine proteinase
intestain - Leptinotarsa decemlineata (Colorado potato
beetle)
Length = 326
Score = 34.7 bits (76), Expect = 1.9
Identities = 13/24 (54%), Positives = 18/24 (75%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GY ++ R+ NN CGIA ASYP++
Sbjct: 303 GYFRIKRDANNLCGIADKASYPIL 326
>UniRef50_Q4C5V5 Cluster: Protein kinase; n=1; Crocosphaera watsonii
WH 8501|Rep: Protein kinase - Crocosphaera watsonii
Length = 590
Score = 33.5 bits (73), Expect = 4.4
Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Frame = -2
Query: 444 FHF*NSVLII*DFLVLFNFIKNICKCVITSSIRYDSLFKI*QLTLGAVILLTFIY-LRDV 268
F F +++ L+++NF K K S Y K + + L + +
Sbjct: 366 FLFVTHIILSPGLLIIYNFQKRYRKIRYLSRKLYRKFKKTYLPQIAMIFFLMILRSFLSI 425
Query: 267 IIFFSLLLFCNYFFLILFRI 208
IF + LFC+Y LILF++
Sbjct: 426 SIFIGIYLFCSYLVLILFKL 445
>UniRef50_Q6R3Q1 Cluster: Cathepsin L-like cysteine proteinase; n=2;
Taeniidae|Rep: Cathepsin L-like cysteine proteinase -
Taenia solium (Pork tapeworm)
Length = 339
Score = 33.5 bits (73), Expect = 4.4
Identities = 13/24 (54%), Positives = 18/24 (75%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAASYPLV 80
GYI MA++ +N CG+AS A +P V
Sbjct: 316 GYIMMAKDYHNMCGVASLADFPYV 339
>UniRef50_A2E346 Cluster: Clan CA, family C1, cathepsin L-like
cysteine peptidase; n=9; Trichomonas vaginalis|Rep: Clan
CA, family C1, cathepsin L-like cysteine peptidase -
Trichomonas vaginalis G3
Length = 306
Score = 33.5 bits (73), Expect = 4.4
Identities = 11/19 (57%), Positives = 16/19 (84%)
Frame = +3
Query: 9 GYIKMARNRNNHCGIASAA 65
GY++M RN+NN CG+A+ A
Sbjct: 282 GYVRMIRNKNNQCGVATEA 300
>UniRef50_Q9BJX3 Cluster: Putative ATPase; n=1; Trypanosoma
cruzi|Rep: Putative ATPase - Trypanosoma cruzi
Length = 201
Score = 33.1 bits (72), Expect = 5.9
Identities = 14/27 (51%), Positives = 20/27 (74%)
Frame = -2
Query: 294 LTFIYLRDVIIFFSLLLFCNYFFLILF 214
L F++L ++FFSLLLFC+Y F + F
Sbjct: 61 LFFVFL---LLFFSLLLFCHYLFFVCF 84
>UniRef50_UPI0000E4A202 Cluster: PREDICTED: similar to Transmembrane
protein 39a; n=3; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Transmembrane protein 39a -
Strongylocentrotus purpuratus
Length = 526
Score = 32.7 bits (71), Expect = 7.7
Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 7/81 (8%)
Frame = -2
Query: 429 SVLII*DFLVLFNFIKN---ICKCVITSSIRYDSLFKI*QLTLGAVILLTFIYLRD---- 271
S+L+ ++ VLF +++ + K + +R +LF L LG + ++ +R
Sbjct: 431 SLLLFCNYYVLFKLLRSRFILGKFMFHDPLRVLNLFVF--LQLGVIATQLYLLIRHSHWH 488
Query: 270 VIIFFSLLLFCNYFFLILFRI 208
+I SLLLFCNY+ +LF++
Sbjct: 489 YVISLSLLLFCNYY--VLFKL 507
>UniRef50_A4Y8H0 Cluster: Putative uncharacterized protein; n=1;
Shewanella putrefaciens CN-32|Rep: Putative
uncharacterized protein - Shewanella putrefaciens CN-32
Length = 382
Score = 32.7 bits (71), Expect = 7.7
Identities = 21/55 (38%), Positives = 33/55 (60%)
Frame = -2
Query: 429 SVLII*DFLVLFNFIKNICKCVITSSIRYDSLFKI*QLTLGAVILLTFIYLRDVI 265
S+LI+ FL+LF FI +I + +++IR+ LF + LG + FIYL V+
Sbjct: 149 SILILNRFLILFIFISSIIVYLCSANIRFKKLFVV---ILGVIF---FIYLFGVL 197
>UniRef50_Q09FA3 Cluster: Heme maturase; n=2; Tetrahymena|Rep: Heme
maturase - Tetrahymena malaccensis
Length = 519
Score = 32.7 bits (71), Expect = 7.7
Identities = 21/84 (25%), Positives = 44/84 (52%)
Frame = -2
Query: 429 SVLII*DFLVLFNFIKNICKCVITSSIRYDSLFKI*QLTLGAVILLTFIYLRDVIIFFSL 250
+++++ F +LF ++++I ++ + I + F I ++L+ ++ I FFS
Sbjct: 31 NLILLKSFFILFYYVESIYVSILNNLINLNYNFII-------ILLIFLLFFNQKIKFFSY 83
Query: 249 LLFCNYFFLILFRIPDVKYNVYVN 178
+LF FF+I F + YN +N
Sbjct: 84 ILF---FFIIFFELL-TSYNYTIN 103
>UniRef50_Q8H166 Cluster: Thiol protease aleurain precursor; n=18;
Magnoliophyta|Rep: Thiol protease aleurain precursor -
Arabidopsis thaliana (Mouse-ear cress)
Length = 358
Score = 32.7 bits (71), Expect = 7.7
Identities = 15/26 (57%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DLGYIKMARNRNNHCGIASAASYPLV 80
D GY KM +N CGIA+ ASYP+V
Sbjct: 333 DKGYFKMEMGKNM-CGIATCASYPVV 357
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 411,632,798
Number of Sequences: 1657284
Number of extensions: 6253141
Number of successful extensions: 13865
Number of sequences better than 10.0: 65
Number of HSP's better than 10.0 without gapping: 13371
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 13850
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48126133708
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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