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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= I10A02NGRL0001_F17
         (623 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP], mitoch...   282   4e-75
UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular organ...   265   7e-70
UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein; ...   257   2e-67
UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5; ...   247   1e-64
UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial...   232   6e-60
UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1; ...   184   1e-45
UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridi...   180   3e-44
UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2; ...   108   1e-22
UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase...   105   7e-22
UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4; Eukaryot...    94   3e-18
UniRef50_Q9H302 Cluster: NADP+-specific isocitrate dehydrogenase...    81   3e-14
UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase...    80   5e-14
UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3...    64   2e-09
UniRef50_P40495 Cluster: Homoisocitrate dehydrogenase, mitochond...    42   0.012
UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5; B...    42   0.016
UniRef50_Q0SI24 Cluster: 3-isopropylmalate dehydrogenase; n=9; B...    41   0.021
UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5; Gammapro...    41   0.021
UniRef50_Q89XA0 Cluster: 3-isopropylmalate dehydrogenase 1; n=3;...    40   0.064
UniRef50_Q80DL8 Cluster: Nuclear antigen 3C; n=1; Cercopithecine...    39   0.11 
UniRef50_UPI000065FA45 Cluster: DNA topoisomerase 2-binding prot...    37   0.34 
UniRef50_Q8E9N3 Cluster: 3-isopropylmalate dehydrogenase; n=148;...    37   0.34 
UniRef50_Q8LG77 Cluster: Isocitrate dehydrogenase [NAD] catalyti...    37   0.45 
UniRef50_A0ZF75 Cluster: 3-isopropylmalate dehydrogenase; n=2; N...    36   0.79 
UniRef50_Q6L2P9 Cluster: Isocitrate dehydrogenase [NADP]; n=2; T...    36   1.0  
UniRef50_Q4P4L8 Cluster: Putative uncharacterized protein; n=1; ...    35   1.4  
UniRef50_P18583 Cluster: SON protein; n=79; cellular organisms|R...    35   1.4  
UniRef50_Q81T67 Cluster: 3-isopropylmalate dehydrogenase; n=9; B...    35   1.8  
UniRef50_UPI0000E7FA5C Cluster: PREDICTED: similar to TAF4 RNA p...    34   2.4  
UniRef50_Q89RM2 Cluster: 3-isopropylmalate dehydrogenase; n=3; P...    34   2.4  
UniRef50_Q7S3X3 Cluster: Putative uncharacterized protein NCU022...    34   3.2  
UniRef50_Q67LW7 Cluster: Tartrate dehydrogenase; n=2; Bacteria|R...    33   4.2  
UniRef50_Q55ME2 Cluster: Putative uncharacterized protein; n=1; ...    33   4.2  
UniRef50_Q12545 Cluster: 3-isopropylmalate dehydrogenase; n=2; H...    33   4.2  
UniRef50_A0Q405 Cluster: 3-isopropylmalate dehydrogenase; n=5; F...    33   5.6  
UniRef50_Q1L2C8 Cluster: Argonaute long form; n=3; Toxoplasma go...    33   5.6  
UniRef50_Q8YCX4 Cluster: 3-isopropylmalate dehydrogenase; n=126;...    33   5.6  
UniRef50_UPI0000E4A818 Cluster: PREDICTED: similar to 1-alpha dy...    32   9.7  
UniRef50_UPI000023DC9B Cluster: hypothetical protein FG02430.1; ...    32   9.7  
UniRef50_Q85286 Cluster: Molluscum contagiosum virus type 1 ORF1...    32   9.7  
UniRef50_Q02AT8 Cluster: Putative esterase precursor; n=1; Solib...    32   9.7  
UniRef50_A5CDH3 Cluster: Isocitrate dehydrogenase, NADP-dependen...    32   9.7  
UniRef50_Q1E6M8 Cluster: Predicted protein; n=1; Coccidioides im...    32   9.7  
UniRef50_A2QHF7 Cluster: Contig An03c0200, complete genome; n=10...    32   9.7  
UniRef50_Q6CWK2 Cluster: Autophagy-related protein 13; n=1; Kluy...    32   9.7  

>UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP],
           mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
           decarboxylase) (IDH) (NADP(+)-specific ICDH); n=493;
           cellular organisms|Rep: Isocitrate dehydrogenase [NADP],
           mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
           decarboxylase) (IDH) (NADP(+)-specific ICDH) - Homo
           sapiens (Human)
          Length = 452

 Score =  282 bits (692), Expect = 4e-75
 Identities = 126/189 (66%), Positives = 147/189 (77%), Gaps = 1/189 (0%)
 Frame = +2

Query: 2   RFKDIFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGFVWACKNYDGDVQSDVV 181
           RFKDIF+E++   YK  FD  KIWYEHRLIDDMVAQ +K SGGFVWACKNYDGDVQSD++
Sbjct: 261 RFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDIL 320

Query: 182 AQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHYRMHQQGKPTSTNPVASIYAWTRGLV 361
           AQG+GSLG+MTSVL+CPDG+T+E+EAAHGTVTRHYR HQ+G+PTSTNP+ASI+AWTRGL 
Sbjct: 321 AQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLE 380

Query: 362 HRAKLDGTPXXXXXXXXXXXXCVECIDSGKMTKDLVICIHGLANTK-EGMYLNTEDFLQA 538
           HR KLDG              CVE ++SG MTKDL  CIHGL+N K    +LNT DFL  
Sbjct: 381 HRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDT 440

Query: 539 IADQLERKL 565
           I   L+R L
Sbjct: 441 IKSNLDRAL 449


>UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular
           organisms|Rep: F12P19.10 protein - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 410

 Score =  265 bits (649), Expect = 7e-70
 Identities = 117/189 (61%), Positives = 148/189 (78%)
 Frame = +2

Query: 2   RFKDIFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGFVWACKNYDGDVQSDVV 181
           RFKDIF+EVY++ +K ++D A IWYEHRLIDDMVA A+K  GG+VWACKNYDGDVQSD +
Sbjct: 222 RFKDIFQEVYEASWKSKYDAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFL 281

Query: 182 AQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHYRMHQQGKPTSTNPVASIYAWTRGLV 361
           AQG+GSLG+MTSVL+CPDG+T+E+EAAHGTVTRH+R+HQ+G  TSTN +ASI+AWTRGL 
Sbjct: 282 AQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLA 341

Query: 362 HRAKLDGTPXXXXXXXXXXXXCVECIDSGKMTKDLVICIHGLANTKEGMYLNTEDFLQAI 541
           HRAKLD               CV  ++SGKMTKDL + IHG +      YLNTE+F+ A+
Sbjct: 342 HRAKLDDNAKLLDFTEKLEAACVGTVESGKMTKDLALIIHG-SKLSRDTYLNTEEFIDAV 400

Query: 542 ADQLERKLS 568
           A +L+ +L+
Sbjct: 401 AAELKERLN 409


>UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein;
           n=6; core eudicotyledons|Rep: Isocitrate
           dehydrogenase-like protein - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 485

 Score =  257 bits (629), Expect = 2e-67
 Identities = 112/185 (60%), Positives = 147/185 (79%)
 Frame = +2

Query: 2   RFKDIFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGFVWACKNYDGDVQSDVV 181
           RFKDIF+EVY++++K++F++  IWYEHRLIDDMVA A+K  GG+VWACKNYDGDVQSD++
Sbjct: 293 RFKDIFQEVYEANWKQKFEEHSIWYEHRLIDDMVAYAVKSEGGYVWACKNYDGDVQSDLL 352

Query: 182 AQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHYRMHQQGKPTSTNPVASIYAWTRGLV 361
           AQG+GSLG+MTSVL+  DG+T+ESEAAHGTVTRH+R+HQ+G+ TSTN +ASI+AWTRGL 
Sbjct: 353 AQGFGSLGLMTSVLLSADGKTLESEAAHGTVTRHFRLHQKGQETSTNSIASIFAWTRGLE 412

Query: 362 HRAKLDGTPXXXXXXXXXXXXCVECIDSGKMTKDLVICIHGLANTKEGMYLNTEDFLQAI 541
           HRAKLD               CV  +++GKMTKDL + IHG       ++LNTE+F+ A+
Sbjct: 413 HRAKLDKNEKLMDFVKKLESSCVNTVETGKMTKDLALLIHG-PKVSRDLFLNTEEFIDAV 471

Query: 542 ADQLE 556
           A +L+
Sbjct: 472 ASKLK 476


>UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5;
           Eukaryota|Rep: Putative uncharacterized protein - Oryza
           sativa subsp. indica (Rice)
          Length = 475

 Score =  247 bits (605), Expect = 1e-64
 Identities = 118/207 (57%), Positives = 146/207 (70%), Gaps = 18/207 (8%)
 Frame = +2

Query: 2   RFKDIFEEVYQSDYKKQFDDAKIW------------------YEHRLIDDMVAQAIKGSG 127
           RFKDIF+E Y++ ++ +FDDA IW                  YEHRLIDDMVA A+K  G
Sbjct: 265 RFKDIFQENYETKWRAKFDDAGIWNMEPYFPPLCPNHFCCGRYEHRLIDDMVAYALKSEG 324

Query: 128 GFVWACKNYDGDVQSDVVAQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHYRMHQQGK 307
           G+VWACKNYDGDVQSD++AQG+GSLG+MTSVL+CPDGRT+E+EAAHGTVTRHYR+HQ+G 
Sbjct: 325 GYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTIEAEAAHGTVTRHYRVHQKGG 384

Query: 308 PTSTNPVASIYAWTRGLVHRAKLDGTPXXXXXXXXXXXXCVECIDSGKMTKDLVICIHGL 487
            TSTN +ASI+AWT GL HRAKLD               CV  ++SGKMTKDL + +HG 
Sbjct: 385 ETSTNSIASIFAWTTGLGHRAKLDDNKRLLDFVQKLEAACVGTVESGKMTKDLALLVHG- 443

Query: 488 ANTKEGMYLNTEDFLQAIADQLERKLS 568
            N     YLNT +F+ A+A+ L  +LS
Sbjct: 444 PNVSRDKYLNTVEFIDAVAEDLRTRLS 470


>UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial;
           n=2; Eurotiomycetidae|Rep: Isocitrate dehydrogenase,
           mitochondrial - Aspergillus terreus (strain NIH 2624)
          Length = 466

 Score =  232 bits (567), Expect = 6e-60
 Identities = 107/191 (56%), Positives = 136/191 (71%), Gaps = 1/191 (0%)
 Frame = +2

Query: 2   RFKDIFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGFVWACKNYDGDVQSDVV 181
           RFKDIF+E+Y+++YKK+FD   IWYEHRLIDDMVAQ IK  GGF+ A KNYDGDVQSD+V
Sbjct: 277 RFKDIFQEIYEAEYKKEFDAKGIWYEHRLIDDMVAQMIKSEGGFIMALKNYDGDVQSDIV 336

Query: 182 AQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHYRMHQQGKPTSTNPVASIYAWTRGLV 361
           AQG+GSLG+MTS L  PDG   ESEAAHGTVTRHYR HQ+G+ TSTNP+ASI+AWTRGLV
Sbjct: 337 AQGFGSLGLMTSTLTTPDGSAFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLV 396

Query: 362 HRAKLDGTPXXXXXXXXXXXXCVECI-DSGKMTKDLVICIHGLANTKEGMYLNTEDFLQA 538
            R +LD TP            C+E + + G MTKDL +        +   ++ T +++ A
Sbjct: 397 QRGQLDNTPDVVTFAEELERACIEVVNEEGIMTKDLAL---SCGRKEREAWVTTREYMAA 453

Query: 539 IADQLERKLSN 571
           +  +L+  L +
Sbjct: 454 VERRLKANLKS 464


>UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 417

 Score =  184 bits (449), Expect = 1e-45
 Identities = 89/188 (47%), Positives = 123/188 (65%)
 Frame = +2

Query: 2   RFKDIFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGFVWACKNYDGDVQSDVV 181
           +FK++F+ V+ +++K +F++A + Y + LIDD+VA+ +K  GGF+WACKNYDGDV SD+V
Sbjct: 235 KFKEVFQTVFDTEFKDRFEEAGLTYFYSLIDDIVARVMKAEGGFIWACKNYDGDVMSDMV 294

Query: 182 AQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHYRMHQQGKPTSTNPVASIYAWTRGLV 361
           +  +GSL MMTSVL+ P G   E EAAHGTV RHY  H +GK TSTN VA+I+AWT  L 
Sbjct: 295 SSAFGSLAMMTSVLVSPQG-YYEYEAAHGTVQRHYYRHLEGKETSTNSVATIFAWTGALR 353

Query: 362 HRAKLDGTPXXXXXXXXXXXXCVECIDSGKMTKDLVICIHGLANTKEGMYLNTEDFLQAI 541
            R +LDG               +  I+SGKMTKDL +    +   +    LN+ DF+ AI
Sbjct: 354 KRGELDGNQKLEEFADKLEKATLSTIESGKMTKDLAL----ITTIENPTVLNSRDFILAI 409

Query: 542 ADQLERKL 565
            + LE+ L
Sbjct: 410 RESLEKML 417


>UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridium
           kluyveri DSM 555
          Length = 401

 Score =  180 bits (437), Expect = 3e-44
 Identities = 89/185 (48%), Positives = 119/185 (64%)
 Frame = +2

Query: 2   RFKDIFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGFVWACKNYDGDVQSDVV 181
           RFKDIF+E+Y ++Y  +F+DA I Y + LIDD VA+ +K  GGF+WACKNYDGDV SD+V
Sbjct: 221 RFKDIFQEIYDTEYDAKFNDAGIEYFYTLIDDAVARVVKSEGGFIWACKNYDGDVMSDMV 280

Query: 182 AQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHYRMHQQGKPTSTNPVASIYAWTRGLV 361
           A  +GSL MMTSVL+ P+G   E EAAHGTV +HY  H +G+ TSTN +A+++AWT  L 
Sbjct: 281 ATAFGSLAMMTSVLVSPEG-YYEYEAAHGTVQKHYYQHLKGQLTSTNSMATLFAWTGALR 339

Query: 362 HRAKLDGTPXXXXXXXXXXXXCVECIDSGKMTKDLVICIHGLANTKEGMYLNTEDFLQAI 541
            R ++DG               +  I+ G MTKDL      L+  +    +NTE+FL  I
Sbjct: 340 KRGEIDGINELVEFADRLENTSIRTIEEGIMTKDLA----SLSELENKKIVNTEEFLLEI 395

Query: 542 ADQLE 556
             +LE
Sbjct: 396 KKRLE 400


>UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. indica (Rice)
          Length = 371

 Score =  108 bits (259), Expect = 1e-22
 Identities = 44/62 (70%), Positives = 54/62 (87%)
 Frame = +2

Query: 2   RFKDIFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGFVWACKNYDGDVQSDVV 181
           RFKDIF+EVY+  +K++F++  IWYEHRLIDDMVA A+K  GG+VWACKNYDGDVQSD +
Sbjct: 96  RFKDIFQEVYEEKWKEKFEENSIWYEHRLIDDMVAYAVKSEGGYVWACKNYDGDVQSDFL 155

Query: 182 AQ 187
           AQ
Sbjct: 156 AQ 157



 Score = 33.1 bits (72), Expect = 5.6
 Identities = 12/23 (52%), Positives = 19/23 (82%)
 Frame = +2

Query: 2   RFKDIFEEVYQSDYKKQFDDAKI 70
           RFKDIF+EVY+  +K++F++  I
Sbjct: 192 RFKDIFQEVYEEKWKEKFEENSI 214


>UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase
           protein; n=2; Rhodobacteraceae|Rep: NADP-dependent
           isocitrate dehydrogenase protein - Sagittula stellata
           E-37
          Length = 459

 Score =  105 bits (253), Expect = 7e-22
 Identities = 59/155 (38%), Positives = 82/155 (52%)
 Frame = -2

Query: 466 QILSHFPTIDAFHTGLFKGECKPLQFWSTVQLSTVNQTPRPSVYRGDGVRGRRLPLLVHA 287
           Q+L H   +        +   K LQ    VQL  V Q   P + R DGV G RL LLV  
Sbjct: 80  QVLGHVAGLHGLDDHPLQRLGKVLQRRVAVQLRAVLQPAGPGIDRRDGVGGGRLALLVLT 139

Query: 286 IVPSHGAVSGFRLHRPSVRTHQY*RHHSQRTVTLRYYIGLHVTVVILTGPYESTGSFYRL 107
           ++  H AV   RLH P++R HQ   HH QR   LR+ + LHV V++L GP E      R 
Sbjct: 140 VMARHRAVRRLRLHDPAIRRHQLRGHHPQRPEALRHRVRLHVAVIVLAGPDELAVPLERA 199

Query: 106 CDHIINQPMLIPNLCVIKLLLVITLIYFFKDVLEP 2
             H+++QP+L+P+   ++LL  + L+   + VLEP
Sbjct: 200 GHHVVDQPVLVPDALRLELLGKLRLVDLLEQVLEP 234


>UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4;
           Eukaryota|Rep: Isocitrate dehydrogenase - Saltugilia
           latimeri
          Length = 158

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 47/121 (38%), Positives = 58/121 (47%)
 Frame = +2

Query: 2   RFKDIFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGFVWACKNYDGDVQSDVV 181
           RFKDIF+EVY+  +K +++ A IWYEHRLIDDM                           
Sbjct: 38  RFKDIFQEVYEKSWKSKYEAAGIWYEHRLIDDMXXXXXXXXXXXXXXXXXXXXXXXXXXX 97

Query: 182 AQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHYRMHQQGKPTSTNPVASIYAWTRGLV 361
                                    AAHG VTRHYR+HQ+G   STN +ASI+AW+RGL 
Sbjct: 98  XXXXXXXXXXXXXXXXXXXXXXXXXAAHGAVTRHYRVHQKGGEASTNSIASIFAWSRGLA 157

Query: 362 H 364
           H
Sbjct: 158 H 158


>UniRef50_Q9H302 Cluster: NADP+-specific isocitrate dehydrogenase;
           n=1; Homo sapiens|Rep: NADP+-specific isocitrate
           dehydrogenase - Homo sapiens (Human)
          Length = 127

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 38/85 (44%), Positives = 52/85 (61%)
 Frame = +2

Query: 314 STNPVASIYAWTRGLVHRAKLDGTPXXXXXXXXXXXXCVECIDSGKMTKDLVICIHGLAN 493
           STNP+ASI+AWTRGL  RAK D               C+E I++G MTKDL  CI GL +
Sbjct: 4   STNPIASIFAWTRGLALRAKTDNNKELAFFANALEEVCIETIEAGFMTKDLAACIKGLPS 63

Query: 494 TKEGMYLNTEDFLQAIADQLERKLS 568
            +   YLNT +F++ + + L+ KL+
Sbjct: 64  AQCSDYLNTFEFMEKLGENLKIKLA 88


>UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase
           protein; n=1; Rhizobium etli CFN 42|Rep: NADP-dependent
           isocitrate dehydrogenase protein - Rhizobium etli
           (strain CFN 42 / ATCC 51251)
          Length = 437

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 50/154 (32%), Positives = 77/154 (50%)
 Frame = -2

Query: 466 QILSHFPTIDAFHTGLFKGECKPLQFWSTVQLSTVNQTPRPSVYRGDGVRGRRLPLLVHA 287
           Q+L H    +     LF+   +  +F   V+L  V +T  P   R + VR   L LL+  
Sbjct: 49  QVLGHEAGFNGVDADLFQRRGELGKFGIVVELGAVGETTGPGEDRCNRVRRGFLTLLMLT 108

Query: 286 IVPSHGAVSGFRLHRPSVRTHQY*RHHSQRTVTLRYYIGLHVTVVILTGPYESTGSFYRL 107
           IV  H  +SGF   R ++   Q   H  +R   LR  IGL V VV+L GP  ++G     
Sbjct: 109 IVAGHRTMSGFGFDRLAIGRQQNRGHQPERAEALRDGIGLDVAVVVLAGPDVASGPLQGR 168

Query: 106 CDHIINQPMLIPNLCVIKLLLVITLIYFFKDVLE 5
            DH+++Q + + +   ++L+L   L+ F +DVLE
Sbjct: 169 GDHVVDQTVFVGDPGFLELILEFGLVDFLEDVLE 202


>UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3;
           Ostreococcus|Rep: COG0538: Isocitrate dehydrogenases -
           Ostreococcus tauri
          Length = 429

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 60/195 (30%), Positives = 88/195 (45%), Gaps = 11/195 (5%)
 Frame = +2

Query: 5   FKDIFEEVYQSDYKKQFDDAKIWYE-----HRLIDDMVAQAIKG-SGGFVWACKNYDGDV 166
           F  I   V+  ++K QF  A +  E     H L D    + ++   GGF  A  NYDGDV
Sbjct: 244 FWQIMRTVFDEEFKAQFVAAGVMKEGEELVHLLSDAATMKLVQWRQGGFGMAAHNYDGDV 303

Query: 167 QSDVVAQGYGSLGMMTSVL--MCPDGRTV-ESEAAHGTVTRHYRMHQQGKPTSTNPVASI 337
            +D +AQ + S G +TS L  +  DG  + E EA+HGTV        +G+ TS NP+  +
Sbjct: 304 LTDELAQVHKSPGFITSNLVGVHEDGTLIKEFEASHGTVADMDEARLRGEETSLNPLGMV 363

Query: 338 YAWTRGLVHRAKLDGTPXXXXXXXXXXXXCV--ECIDSGKMTKDLVICIHGLANTKEGMY 511
                 + H A +                 V  +    GK T+DL  C  G +       
Sbjct: 364 EGLIGAMNHAADVHNIDRDRTHAFTTKMRTVIHQLFREGKGTRDL--C--GPSG------ 413

Query: 512 LNTEDFLQAIADQLE 556
           L TE F+ A+A++L+
Sbjct: 414 LTTEQFIDAVAERLD 428


>UniRef50_P40495 Cluster: Homoisocitrate dehydrogenase,
           mitochondrial precursor; n=33; Dikarya|Rep:
           Homoisocitrate dehydrogenase, mitochondrial precursor -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 371

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
 Frame = +2

Query: 5   FKDIFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVV 181
           F++I +EVY+S+  K     +I Y  +++D MV +  +    F V    N  GD+ SD  
Sbjct: 217 FREICKEVYESNKDKY---GQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGA 273

Query: 182 AQGYGSLGMMTSVLMCPDGRTVESEAAHGT 271
           A   GSLG++ S  + P+   V  E  HG+
Sbjct: 274 AALVGSLGVVPSANVGPE--IVIGEPCHGS 301


>UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5;
           Bacteria|Rep: 3-isopropylmalate dehydrogenase -
           Symbiobacterium thermophilum
          Length = 357

 Score = 41.5 bits (93), Expect = 0.016
 Identities = 43/136 (31%), Positives = 59/136 (43%), Gaps = 5/136 (3%)
 Frame = +2

Query: 74  YEHRLIDDMVAQAI-KGSGGFVWACKNYDGDVQSDVVAQGYGSLGMMTSVLMCPD----G 238
           Y+ +LID   A  I + +   V  C N DGD+ SD+V   YGS+    S+L+  D     
Sbjct: 206 YDPQLIDAAYALLIARATRPLVIPCLNRDGDILSDLVLALYGSIAGSESLLIAFDEQFNP 265

Query: 239 RTVESEAAHGTVTRHYRMHQQGKPTSTNPVASIYAWTRGLVHRAKLDGTPXXXXXXXXXX 418
           R V +EA HGT         QGK    NP+A   A   G + +   D  P          
Sbjct: 266 RVVMAEAPHGTAP-----SLQGK-NLANPLAMQLA--AGALLKQMPD--PEYQRAGAAIQ 315

Query: 419 XXCVECIDSGKMTKDL 466
             C++ +  G  T DL
Sbjct: 316 EACLQAVAQGVRTADL 331


>UniRef50_Q0SI24 Cluster: 3-isopropylmalate dehydrogenase; n=9;
           Bacteria|Rep: 3-isopropylmalate dehydrogenase -
           Rhodococcus sp. (strain RHA1)
          Length = 365

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 1/105 (0%)
 Frame = +2

Query: 5   FKDIFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVV 181
           F+D+  EV Q DY     D +I  EH  +D M A  ++    F V   +N  GD+ SD+ 
Sbjct: 205 FRDVCREVGQRDYP----DVRIDDEH--VDAMTAHLVRRGRDFDVVVTENMFGDILSDLT 258

Query: 182 AQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHYRMHQQGKPTS 316
            +  GSLG   S+        V ++AAHG        H +  PT+
Sbjct: 259 GELSGSLGTAPSI--NSSETKVMAQAAHGAAP-DIAGHNRANPTA 300


>UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5;
           Gammaproteobacteria|Rep: Isocitrate dehydrogenase -
           Marinobacter sp. ELB17
          Length = 582

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
 Frame = +2

Query: 134 VWACKNYDGDVQSDVVAQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHY--RMHQQGK 307
           ++  +N DGD+ SD+ A   GSL   +S++      T+  EA HGT    Y   +   GK
Sbjct: 440 LYPAQNLDGDIFSDISAALGGSLATASSIIESKSS-TMLFEAPHGTAHDLYLKYLESNGK 498

Query: 308 PTSTNPVASIYAWTRGL 358
               NP A IYA    L
Sbjct: 499 DAHFNPSALIYALANAL 515


>UniRef50_Q89XA0 Cluster: 3-isopropylmalate dehydrogenase 1; n=3;
           Bacteria|Rep: 3-isopropylmalate dehydrogenase 1 -
           Bradyrhizobium japonicum
          Length = 379

 Score = 39.5 bits (88), Expect = 0.064
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
 Frame = +2

Query: 14  IFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVVAQG 190
           ++ E   + ++ +F D ++   H  +D+   Q ++    F V    N  GD+ SD  A  
Sbjct: 206 LWREEVTALHEAEFSDVEL--THLYVDNAAMQIVRAPSQFDVMVTCNIFGDILSDCAAMA 263

Query: 191 YGSLGMMTSVLMCPDGRTVESEAAHGTV 274
            GSLGM+ SV + P  R    +A +  V
Sbjct: 264 SGSLGMLPSVSLGPPDRLGRRKALYEPV 291


>UniRef50_Q80DL8 Cluster: Nuclear antigen 3C; n=1; Cercopithecine
           herpesvirus 12|Rep: Nuclear antigen 3C - Cercopithecine
           herpesvirus 12 (CeHV-12) (Baboon herpesvirus)
          Length = 975

 Score = 38.7 bits (86), Expect = 0.11
 Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 4/113 (3%)
 Frame = -1

Query: 431 PHRPLQGRVQTAPVLEYRPA*HGEPNPSSKRISRRRGSWTSASLVGACDSAE---SRCRE 261
           P  P Q R    P++         PN  S+ +S R G    A  V  CD  E       +
Sbjct: 450 PPEPTQQRQAELPIITVHEPPREHPNGPSEGVSERAGRRRGACAVYDCDVIEVIDVESSD 509

Query: 260 RLQTPPSVRQDTSVLT-SSFPANRNPALLHRTARHRRNSYRPIRIHRILLSPV 105
              TPP  RQ T+V T  S  ++  P         R+   +  R+ R   +PV
Sbjct: 510 EEVTPPQKRQGTAVSTPGSMTSSSMPRPTQANEAQRQRKSKASRLERRQRAPV 562


>UniRef50_UPI000065FA45 Cluster: DNA topoisomerase 2-binding protein 1
            (DNA topoisomerase II-binding protein 1) (DNA
            topoisomerase IIbeta-binding protein 1) (TopBP1).; n=1;
            Takifugu rubripes|Rep: DNA topoisomerase 2-binding
            protein 1 (DNA topoisomerase II-binding protein 1) (DNA
            topoisomerase IIbeta-binding protein 1) (TopBP1). -
            Takifugu rubripes
          Length = 1412

 Score = 37.1 bits (82), Expect = 0.34
 Identities = 26/102 (25%), Positives = 42/102 (41%), Gaps = 7/102 (6%)
 Frame = -1

Query: 359  PNPSSKRISRRRGSWTSASLV--GACDSAESRCRERLQTPPSVRQDTSVLTS-----SFP 201
            P P+++   + R S T + LV   ACD  +    ++  TPP+  Q+  +LT      +FP
Sbjct: 1124 PPPTTETCPQFRDSMTDSELVEMAACDVIDQHMGQKFTTPPTKEQENDLLTPEAPSIAFP 1183

Query: 200  ANRNPALLHRTARHRRNSYRPIRIHRILLSPVRPYHQSAYAH 75
                P       R +         H   LS + P  +  Y+H
Sbjct: 1184 LANPPVAPEPEVRSKDLRDNCQHFHTFQLSSLSPQERIDYSH 1225


>UniRef50_Q8E9N3 Cluster: 3-isopropylmalate dehydrogenase; n=148;
           Bacteria|Rep: 3-isopropylmalate dehydrogenase -
           Shewanella oneidensis
          Length = 364

 Score = 37.1 bits (82), Expect = 0.34
 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
 Frame = +2

Query: 53  FDDAKIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVVAQGYGSLGMMTSVLMC 229
           F D ++  EH  ID+   Q ++    F V  C N  GD+ SD +A   GS+G+++S  M 
Sbjct: 214 FPDVEL--EHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDEIAMLTGSMGLLSSASMN 271

Query: 230 PDG 238
             G
Sbjct: 272 STG 274


>UniRef50_Q8LG77 Cluster: Isocitrate dehydrogenase [NAD] catalytic
           subunit 6, mitochondrial precursor (EC 1.1.1.41)
           (Isocitric dehydrogenase 6) (NAD(+)-specific ICDH 6);
           n=10; cellular organisms|Rep: Isocitrate dehydrogenase
           [NAD] catalytic subunit 6, mitochondrial precursor (EC
           1.1.1.41) (Isocitric dehydrogenase 6) (NAD(+)-specific
           ICDH 6) - Arabidopsis thaliana (Mouse-ear cress)
          Length = 374

 Score = 36.7 bits (81), Expect = 0.45
 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
 Frame = +2

Query: 65  KIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVVAQGYGSLGMMTSVLMCPDGR 241
           +I+YE  +ID+     +K    F V    N  GD+ SD+ A   G LG+  S+ +  DG 
Sbjct: 236 EIYYEKVVIDNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLVGGLGLTPSMNIGEDGI 295

Query: 242 TVESEAAHGT 271
            + +EA HG+
Sbjct: 296 AL-AEAVHGS 304


>UniRef50_A0ZF75 Cluster: 3-isopropylmalate dehydrogenase; n=2;
           Nostocaceae|Rep: 3-isopropylmalate dehydrogenase -
           Nodularia spumigena CCY 9414
          Length = 422

 Score = 35.9 bits (79), Expect = 0.79
 Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
 Frame = +2

Query: 50  QFDDAKIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVVAQGYGSLGMMTSVLM 226
           QF D  +  E  L+D++  Q +     F V    N  GD+ SD+     GSLG++ S  +
Sbjct: 261 QFPDVIV--EPMLVDNLAMQMVMNPQRFDVILASNLFGDILSDIGGALVGSLGLLGSASL 318

Query: 227 CPDGRTVESEAAHGT 271
             DG  +  EA HGT
Sbjct: 319 NADGFGL-YEAIHGT 332


>UniRef50_Q6L2P9 Cluster: Isocitrate dehydrogenase [NADP]; n=2;
           Thermoplasmatales|Rep: Isocitrate dehydrogenase [NADP] -
           Picrophilus torridus
          Length = 392

 Score = 35.5 bits (78), Expect = 1.0
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
 Frame = +2

Query: 35  SDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVVAQGYGSLGMM 211
           SDY  + DD KI     + D+M  Q I     + +    N DGD  SD      G++G +
Sbjct: 236 SDYVSRDDDKKIIINDIIADNMFQQIITRPDEYQLILAPNVDGDYISDAAGALIGNIGTL 295

Query: 212 TSVLMCPDGRTVESEAAHGTVTRH 283
               +  +G     EA HGT  ++
Sbjct: 296 GGANIGDNGAMF--EAVHGTAPKY 317


>UniRef50_Q4P4L8 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 577

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
 Frame = +2

Query: 44  KKQFDDAKIWYEHRLIDDMVAQAIKGSGGFVWACKNYDGDVQSDVVAQ-GYGSLGMMTSV 220
           K++ +D+K   + +  D      ++G    V AC + D D  +DV  Q      G  T  
Sbjct: 81  KERTEDSKEDSDVQAEDTQPEHEVRGQRASVTACSSTDADRSADVPKQMDAAGDGECTPE 140

Query: 221 LMCPDGRTVESEAAHGTVTRHYRMHQQGKPTSTNPVASIYAWTRG 355
            + P    ++S +  G V  +Y     G+   T P+AS  + T+G
Sbjct: 141 DLLPGWIPIKSRSGQGEV--YYYNEDTGESRWTKPIASSQSGTKG 183


>UniRef50_P18583 Cluster: SON protein; n=79; cellular organisms|Rep:
            SON protein - Homo sapiens (Human)
          Length = 2426

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
 Frame = -1

Query: 353  PSSKRISRRRGSWTSASLVGACDSAESRCRERLQTPPSVRQDTSVLTSSFPANRN--PAL 180
            PS +R SR  G   S S+     S  SR   R    PS R  T    S  P+ R+  P+ 
Sbjct: 1934 PSRRRRSRSVGRRRSFSI---SPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990

Query: 179  LHRTARHRRNSYRPIRIHRILLSPVR 102
              RT   RR S   +R     +SPVR
Sbjct: 1991 RSRTPSRRRRSRSVVRRRSFSISPVR 2016


>UniRef50_Q81T67 Cluster: 3-isopropylmalate dehydrogenase; n=9;
           Bacillus cereus group|Rep: 3-isopropylmalate
           dehydrogenase - Bacillus anthracis
          Length = 354

 Score = 34.7 bits (76), Expect = 1.8
 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
 Frame = +2

Query: 77  EHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVVAQGYGSLGMMTSVLMCPDGRTVES 253
           EH L+D    + I+  G F V   +N  GD+ SD  +   GSLGM+ S      G ++  
Sbjct: 210 EHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-Y 268

Query: 254 EAAHGT 271
           E  HG+
Sbjct: 269 EPIHGS 274


>UniRef50_UPI0000E7FA5C Cluster: PREDICTED: similar to TAF4 RNA
           polymerase II, TATA box binding protein (TBP)-associated
           factor, 135kDa; n=2; Gallus gallus|Rep: PREDICTED:
           similar to TAF4 RNA polymerase II, TATA box binding
           protein (TBP)-associated factor, 135kDa - Gallus gallus
          Length = 1437

 Score = 34.3 bits (75), Expect = 2.4
 Identities = 16/37 (43%), Positives = 19/37 (51%)
 Frame = -1

Query: 209 SFPANRNPALLHRTARHRRNSYRPIRIHRILLSPVRP 99
           S P    PA LHRT  H R  +RP++    L  PV P
Sbjct: 30  SGPVGPAPACLHRTRSHYRCGWRPVQARLRLAGPVNP 66


>UniRef50_Q89RM2 Cluster: 3-isopropylmalate dehydrogenase; n=3;
           Proteobacteria|Rep: 3-isopropylmalate dehydrogenase -
           Bradyrhizobium japonicum
          Length = 365

 Score = 34.3 bits (75), Expect = 2.4
 Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
 Frame = +2

Query: 86  LIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVVAQGYGSLGMMTSVLMCPDGRTVESEAA 262
           L+D M+A  ++    F V    N  GD+ SD+ A+  GSLG+  S+ +    R   ++AA
Sbjct: 226 LVDAMMAHVVRNPDRFDVIVATNMFGDILSDLTAELSGSLGLGGSLNV--GDRYAMAQAA 283

Query: 263 HGT 271
           HG+
Sbjct: 284 HGS 286


>UniRef50_Q7S3X3 Cluster: Putative uncharacterized protein
           NCU02216.1; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein NCU02216.1 - Neurospora crassa
          Length = 493

 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/85 (28%), Positives = 37/85 (43%)
 Frame = +2

Query: 119 GSGGFVWACKNYDGDVQSDVVAQGYGSLGMMTSVLMCPDGRTVESEAAHGTVTRHYRMHQ 298
           G+ G+ W    YDGDV +    Q   +L   T+ L+     T E EA    VT +     
Sbjct: 383 GTCGYRWNVGKYDGDVSNGPAGQEMSALAAFTTYLI-----TEEHEAVKPLVTNNTGGQS 437

Query: 299 QGKPTSTNPVASIYAWTRGLVHRAK 373
           +G P +    A++ + +  L  R K
Sbjct: 438 RGNPNAGGTPATVMSMSE-LTERDK 461


>UniRef50_Q67LW7 Cluster: Tartrate dehydrogenase; n=2; Bacteria|Rep:
           Tartrate dehydrogenase - Symbiobacterium thermophilum
          Length = 359

 Score = 33.5 bits (73), Expect = 4.2
 Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
 Frame = +2

Query: 17  FEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVVAQGY 193
           ++E++    +++F +   W  H  ID + A  +     F V    N  GD+ +D+     
Sbjct: 200 WDEIFNEIGEREFPEVNRWLCH--IDALAANFVLKPDEFDVVVASNLFGDILTDLGGAIM 257

Query: 194 GSLGMMTSVLMCPDGRTVES-EAAHGTVTRHYRMHQQGKPTSTNPVASIYAWTRGLVHRA 370
           GS+GM  S  + P+ R     E  HG+          G+  + NPV  I++ +  L H  
Sbjct: 258 GSIGMAASANINPERRYPSMFEPVHGSAP-----DIAGRGIA-NPVGQIWSVSLMLEHLG 311

Query: 371 KLD 379
           + D
Sbjct: 312 RAD 314


>UniRef50_Q55ME2 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 529

 Score = 33.5 bits (73), Expect = 4.2
 Identities = 16/36 (44%), Positives = 20/36 (55%)
 Frame = +2

Query: 128 GFVWACKNYDGDVQSDVVAQGYGSLGMMTSVLMCPD 235
           G   ACKN DGD + +   +G  S  M TS L+ PD
Sbjct: 52  GTTMACKNEDGDEEEEADVEGILSPTMDTSTLLSPD 87


>UniRef50_Q12545 Cluster: 3-isopropylmalate dehydrogenase; n=2;
           Hypocreales|Rep: 3-isopropylmalate dehydrogenase -
           Cephalosporium acremonium (Acremonium chrysogenum)
          Length = 380

 Score = 33.5 bits (73), Expect = 4.2
 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
 Frame = +2

Query: 14  IFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGF--VWACKNYDGDVQSDVVAQ 187
           ++  +    + K+F D  I  +H+L D M    ++    F  V    N  GD+ SD+   
Sbjct: 205 LWRRITSDIFAKEFPD--ITLQHQLADSMAMLMVRDPRRFNGVIHTDNTFGDILSDISGA 262

Query: 188 GYGSLGMMTSVLMC 229
             G+LG+M S  +C
Sbjct: 263 ITGTLGLMPSASLC 276


>UniRef50_A0Q405 Cluster: 3-isopropylmalate dehydrogenase; n=5;
           Francisella tularensis|Rep: 3-isopropylmalate
           dehydrogenase - Francisella tularensis subsp. novicida
           (strain U112)
          Length = 359

 Score = 33.1 bits (72), Expect = 5.6
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
 Frame = +2

Query: 35  SDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVVAQGYGSLGMM 211
           ++  K +   K+   H  +D+   Q +     F V    N  GD+ SD+ +   GS+G++
Sbjct: 209 NEVAKDYPSVKV--NHMYVDNCAMQMVLNPSQFDVMVTGNLFGDIISDLASVLPGSIGLV 266

Query: 212 TSVLMCPDGRTVESEAAHGTVTRHYRMHQQGKPTSTNPVASI 337
            S+ +  DG  +  E + G+    Y +  QGK    NP+A I
Sbjct: 267 PSISLNKDGFGL-YEPSGGSA---YDIKGQGK---ANPIAQI 301


>UniRef50_Q1L2C8 Cluster: Argonaute long form; n=3; Toxoplasma
           gondii|Rep: Argonaute long form - Toxoplasma gondii
          Length = 743

 Score = 33.1 bits (72), Expect = 5.6
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = -1

Query: 416 QGRVQTAPVLEYRPA*HGEPNPSSKRISRRRGSW 315
           QGRV  +P+++YR    G P  SSK +   +G W
Sbjct: 264 QGRVLESPLIKYREVPGGGPGRSSKTVRPAQGDW 297


>UniRef50_Q8YCX4 Cluster: 3-isopropylmalate dehydrogenase; n=126;
           Bacteria|Rep: 3-isopropylmalate dehydrogenase - Brucella
           melitensis
          Length = 370

 Score = 33.1 bits (72), Expect = 5.6
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
 Frame = +2

Query: 62  AKIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSDVVAQGYGSLGMMTSV-LMCPD 235
           A +  EH L D    Q ++    F V    N  GD+ SDV A   GSLGM+ S  L   D
Sbjct: 216 ADVQLEHMLADAGGMQLVRWPKQFDVILTDNLFGDLLSDVAAMLTGSLGMLPSASLGAAD 275

Query: 236 GRTVESEAAHGTVTRHYRMHQQGKPTSTNPVASI 337
            +T + +A +  V  H            NP+A I
Sbjct: 276 SKTGKRKALYEPV--HGSAPDIAGKGIANPIAMI 307


>UniRef50_UPI0000E4A818 Cluster: PREDICTED: similar to 1-alpha
           dynein heavy chain; n=4; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to 1-alpha dynein
           heavy chain - Strongylocentrotus purpuratus
          Length = 2880

 Score = 32.3 bits (70), Expect = 9.7
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
 Frame = +2

Query: 269 TVTRHYRMHQQGKPTSTN--PVASIYAWTRGLVHRAK 373
           TV   ++ +Q   P S N  PVA   AW R L HR K
Sbjct: 713 TVQALFKQYQHNPPVSKNQPPVAGAIAWERSLFHRIK 749


>UniRef50_UPI000023DC9B Cluster: hypothetical protein FG02430.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG02430.1 - Gibberella zeae PH-1
          Length = 636

 Score = 32.3 bits (70), Expect = 9.7
 Identities = 24/69 (34%), Positives = 35/69 (50%)
 Frame = -1

Query: 605 LIIVTRTISRVSLIVCVPADRRLPVGSPRCLSTCPL*CSPSRECKSPNP*SFSHYRCIPH 426
           +I V  T   +++ V   A RRLP G P   ++C +  +P+  C+ P+   FSH    P 
Sbjct: 542 IICVIITSGLMAVAVFTTALRRLPTGMP-VAASCSVAIAPA--CRQPD--GFSHPEEAPL 596

Query: 425 RPLQGRVQT 399
            PLQ  V T
Sbjct: 597 LPLQWGVMT 605


>UniRef50_Q85286 Cluster: Molluscum contagiosum virus type 1 ORF1
           and ORF2 DNA; n=1; Molluscum contagiosum virus subtype
           1|Rep: Molluscum contagiosum virus type 1 ORF1 and ORF2
           DNA - Molluscum contagiosum virus subtype 1 (MOCV)
           (MCVI)
          Length = 121

 Score = 32.3 bits (70), Expect = 9.7
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
 Frame = -1

Query: 317 WTSASLVGACDSAESR---CRERLQTPPSVR-QDTSVLTSSFPANRNPALLHRTARHRRN 150
           W       A D   SR   CR+R+Q+    R   +S + ++ PA R P+   RT R R N
Sbjct: 36  WLEKCCALASDHTRSRTGTCRQRMQSTALFRAHSSSSVAAAMPARRRPSTRSRT-RVRAN 94

Query: 149 SYRPIR 132
           + +P R
Sbjct: 95  ARKPRR 100


>UniRef50_Q02AT8 Cluster: Putative esterase precursor; n=1;
           Solibacter usitatus Ellin6076|Rep: Putative esterase
           precursor - Solibacter usitatus (strain Ellin6076)
          Length = 536

 Score = 32.3 bits (70), Expect = 9.7
 Identities = 13/37 (35%), Positives = 22/37 (59%)
 Frame = -2

Query: 226 HQY*RHHSQRTVTLRYYIGLHVTVVILTGPYESTGSF 116
           H Y     +R  T+  Y+G H  +++ +GP E+TG+F
Sbjct: 60  HGYDADTRERDNTMAAYVGTHDLILVDSGPVETTGTF 96


>UniRef50_A5CDH3 Cluster: Isocitrate dehydrogenase, NADP-dependent;
           n=6; Rickettsiales|Rep: Isocitrate dehydrogenase,
           NADP-dependent - Orientia tsutsugamushi (strain Boryong)
           (Rickettsia tsutsugamushi)
          Length = 519

 Score = 32.3 bits (70), Expect = 9.7
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
 Frame = +2

Query: 2   RFKD-IFEEVYQSDYKKQFDDAKIWYEHRLIDDMVAQAIKGSGGF-VWACKNYDGDVQSD 175
           +F D IF + + ++   Q+ + ++  +H LID   A+ I     F V    N  GD+ SD
Sbjct: 180 KFTDGIFHKTF-NEIASQYSNIQV--DHYLIDIGSARLISSPQKFDVIVTSNLYGDILSD 236

Query: 176 VVAQGYGSLGMMTSVLMCPDGRTVESEAAHGT 271
           + A+  GS+G+  S  +  D      EA HG+
Sbjct: 237 IAAKISGSIGLAGSANIGKD--YAMFEAVHGS 266


>UniRef50_Q1E6M8 Cluster: Predicted protein; n=1; Coccidioides
           immitis|Rep: Predicted protein - Coccidioides immitis
          Length = 147

 Score = 32.3 bits (70), Expect = 9.7
 Identities = 26/113 (23%), Positives = 48/113 (42%), Gaps = 3/113 (2%)
 Frame = -1

Query: 347 SKRISRRRGSWTSASLVGACDSAESRCRERLQTPPSVRQDTSVLTSSFPANRNPALLHRT 168
           +K I R    W + ++  +  S ++  + RL  P    Q TS  +  F  +  P+     
Sbjct: 10  TKHIQRLLTRWPTDAIRPSSVSVQTYLQSRLTPPAPETQSTSRWSQLFRKSSPPSQPSTA 69

Query: 167 ARHRRNSYRPIRIHR---ILLSPVRPYHQSAYAHTKSLRHQTASCNHFDILLQ 18
               ++S  P+   +    L S +   +Q  Y    SLR+  +  ++FD LL+
Sbjct: 70  TSSTQSSEEPLLSSQNVNALYSLLENRYQKKYPLPNSLRYPASQSDYFDKLLK 122


>UniRef50_A2QHF7 Cluster: Contig An03c0200, complete genome; n=10;
           Eurotiomycetidae|Rep: Contig An03c0200, complete genome
           - Aspergillus niger
          Length = 551

 Score = 32.3 bits (70), Expect = 9.7
 Identities = 14/40 (35%), Positives = 23/40 (57%)
 Frame = -1

Query: 491 SPSRECKSPNP*SFSHYRCIPHRPLQGRVQTAPVLEYRPA 372
           SPS    SP    +++Y+ +PH PL  + +T P L+  P+
Sbjct: 348 SPSSPAPSPPSPQYTNYKWVPHVPLPPQHKTPPPLQIPPS 387


>UniRef50_Q6CWK2 Cluster: Autophagy-related protein 13; n=1;
           Kluyveromyces lactis|Rep: Autophagy-related protein 13 -
           Kluyveromyces lactis (Yeast) (Candida sphaerica)
          Length = 684

 Score = 32.3 bits (70), Expect = 9.7
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
 Frame = -1

Query: 287 DSAESRCRERLQTPPSVRQDTSVLTSSFPANRNPALLHRTARHRRNSYRPI--RIHRILL 114
           ++  S   + + +P S+R   S+  SS+P N+ P L H    H   S      + H+  +
Sbjct: 587 NAGTSTTEQVMGSPRSIR---SISVSSYPRNQLP-LKHLNLSHPTTSATTTHAKFHKSEM 642

Query: 113 SPVRPYHQSAYAHTKSLRHQTASCNHFD 30
           SP   + + A  HT S  H ++  N  D
Sbjct: 643 SPDPLHTEGAQPHTSSQHHNSSQKNDED 670


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 668,653,417
Number of Sequences: 1657284
Number of extensions: 15253045
Number of successful extensions: 43521
Number of sequences better than 10.0: 44
Number of HSP's better than 10.0 without gapping: 41419
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 43477
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 45636850930
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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