Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0001_D15
(655 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA ... 277 2e-73
UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to 3-hydroxya... 233 2e-60
UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30; Coelom... 218 1e-55
UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella ve... 203 3e-51
UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|R... 190 3e-47
UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 171 9e-42
UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 157 3e-37
UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5; Alphaproteobacter... 152 8e-36
UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 148 1e-34
UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3; ... 144 1e-33
UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain ... 143 4e-33
UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 137 2e-31
UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 126 5e-28
UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 124 1e-27
UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3; ... 124 2e-27
UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 123 3e-27
UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 123 4e-27
UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 - Cl... 119 5e-26
UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 118 2e-25
UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 115 9e-25
UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 113 5e-24
UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 111 1e-23
UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 108 1e-22
UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1; Bre... 107 2e-22
UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 107 3e-22
UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2... 107 3e-22
UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4; S... 107 3e-22
UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 105 1e-21
UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1; ... 104 2e-21
UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 104 2e-21
UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 103 4e-21
UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; A... 102 9e-21
UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 100 3e-20
UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1; ... 100 3e-20
UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 99 8e-20
UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 99 1e-19
UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 99 1e-19
UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; S... 98 2e-19
UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN ful... 97 4e-19
UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 97 4e-19
UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9; B... 97 4e-19
UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6... 96 6e-19
UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 96 6e-19
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 96 7e-19
UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; B... 96 7e-19
UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 95 1e-18
UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1; ... 95 1e-18
UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24; ... 95 1e-18
UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase N... 94 2e-18
UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 93 5e-18
UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precurs... 93 5e-18
UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 92 9e-18
UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,... 92 1e-17
UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 91 2e-17
UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 91 2e-17
UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 90 4e-17
UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 89 1e-16
UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 88 2e-16
UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;... 88 2e-16
UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 87 3e-16
UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 87 5e-16
UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 86 6e-16
UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; H... 86 6e-16
UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4; Trichoco... 86 8e-16
UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3... 85 2e-15
UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 84 2e-15
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 84 3e-15
UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 84 3e-15
UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome. prec... 83 4e-15
UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 83 6e-15
UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 83 7e-15
UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 83 7e-15
UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 83 7e-15
UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA dehydrogenase/3-hydro... 82 1e-14
UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Re... 82 1e-14
UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 81 2e-14
UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 81 2e-14
UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 81 2e-14
UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 81 2e-14
UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like pr... 81 2e-14
UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 81 3e-14
UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 80 4e-14
UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 79 7e-14
UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 79 7e-14
UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 79 1e-13
UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 78 2e-13
UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation m... 78 2e-13
UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 77 3e-13
UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 77 4e-13
UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8... 77 5e-13
UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 77 5e-13
UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 77 5e-13
UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 76 6e-13
UniRef50_O69856 Cluster: Fatty acid oxidation complex alpha-subu... 75 1e-12
UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 75 1e-12
UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 75 1e-12
UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex t... 75 1e-12
UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 74 3e-12
UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 74 3e-12
UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 74 3e-12
UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5; Tri... 73 5e-12
UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; c... 73 5e-12
UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 73 6e-12
UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 73 6e-12
UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 73 8e-12
UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 72 1e-11
UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 72 1e-11
UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9; G... 72 1e-11
UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 72 1e-11
UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 72 1e-11
UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 72 1e-11
UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 71 2e-11
UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 71 2e-11
UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 71 2e-11
UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 71 2e-11
UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subun... 71 3e-11
UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenas... 70 4e-11
UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 70 4e-11
UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase, m... 70 4e-11
UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase; ... 69 7e-11
UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 69 1e-10
UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 69 1e-10
UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; B... 69 1e-10
UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 69 1e-10
UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole gen... 69 1e-10
UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 68 2e-10
UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 68 2e-10
UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB... 68 2e-10
UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein ... 67 3e-10
UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10
UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 66 5e-10
UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular organi... 66 5e-10
UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; P... 66 7e-10
UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 66 9e-10
UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD bi... 65 1e-09
UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 65 2e-09
UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 65 2e-09
UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep... 64 2e-09
UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10; ... 64 2e-09
UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 64 2e-09
UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 64 2e-09
UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 64 3e-09
UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 64 3e-09
UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 64 3e-09
UniRef50_Q5LVG3 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 64 4e-09
UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 64 4e-09
UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 63 5e-09
UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n... 63 6e-09
UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA hydratase/3-hydroxya... 62 9e-09
UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 62 9e-09
UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 62 9e-09
UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 62 9e-09
UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16; ... 62 1e-08
UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:... 62 1e-08
UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8; A... 62 1e-08
UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation m... 62 1e-08
UniRef50_Q5LVD0 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 61 2e-08
UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:... 61 2e-08
UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 61 3e-08
UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA... 60 3e-08
UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 60 3e-08
UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 60 3e-08
UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 60 3e-08
UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 60 5e-08
UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 60 5e-08
UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;... 60 5e-08
UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 60 5e-08
UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit, mit... 60 5e-08
UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA dehydroge... 60 6e-08
UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 59 8e-08
UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 59 8e-08
UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 59 8e-08
UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 59 8e-08
UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;... 59 1e-07
UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48; ... 59 1e-07
UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA dehy... 59 1e-07
UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit ... 59 1e-07
UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2; Alphapr... 59 1e-07
UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 59 1e-07
UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 59 1e-07
UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 59 1e-07
UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 58 2e-07
UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 58 2e-07
UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 58 2e-07
UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified ... 58 2e-07
UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=3... 57 4e-07
UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44; ... 57 4e-07
UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;... 57 4e-07
UniRef50_A2QA05 Cluster: Catalytic activity:; n=4; Trichocomacea... 57 4e-07
UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 56 6e-07
UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 56 7e-07
UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 56 1e-06
UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 56 1e-06
UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit al... 56 1e-06
UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2; Bord... 55 1e-06
UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 55 1e-06
UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella ve... 55 1e-06
UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 55 2e-06
UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 55 2e-06
UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 55 2e-06
UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit al... 54 2e-06
UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 54 3e-06
UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 54 3e-06
UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 54 3e-06
UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius s... 53 5e-06
UniRef50_A3T2M8 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 53 5e-06
UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 53 7e-06
UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2; Si... 53 7e-06
UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 53 7e-06
UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase r... 53 7e-06
UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 52 9e-06
UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep: ... 52 2e-05
UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 52 2e-05
UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA dehydrogena... 52 2e-05
UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 52 2e-05
UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 52 2e-05
UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13; c... 52 2e-05
UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 52 2e-05
UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit al... 52 2e-05
UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit al... 52 2e-05
UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;... 51 2e-05
UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 51 2e-05
UniRef50_Q5P607 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 51 3e-05
UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 4e-05
UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 50 5e-05
UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; V... 50 5e-05
UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 50 6e-05
UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 50 6e-05
UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein NCU043... 50 6e-05
UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 49 9e-05
UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 49 9e-05
UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 49 9e-05
UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;... 49 9e-05
UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 49 9e-05
UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit ... 49 9e-05
UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;... 49 9e-05
UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; X... 49 1e-04
UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 49 1e-04
UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC... 49 1e-04
UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 48 1e-04
UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation c... 48 1e-04
UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 1e-04
UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 48 2e-04
UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 48 2e-04
UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 48 3e-04
UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 48 3e-04
UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 3e-04
UniRef50_A3VIL7 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 48 3e-04
UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 3e-04
UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 47 3e-04
UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 47 5e-04
UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 47 5e-04
UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 47 5e-04
UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 46 6e-04
UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 46 6e-04
UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;... 46 8e-04
UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;... 46 0.001
UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 45 0.001
UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 45 0.001
UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;... 45 0.002
UniRef50_Q1YHC5 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 45 0.002
UniRef50_Q1GNH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=7... 45 0.002
UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1; C... 44 0.002
UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 43 0.006
UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 43 0.007
UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3; Lacto... 42 0.010
UniRef50_A6FFH1 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 42 0.013
UniRef50_Q0UJN7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 42 0.017
UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 41 0.023
UniRef50_Q01UM7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 41 0.023
UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;... 41 0.030
UniRef50_Q08426 Cluster: Peroxisomal bifunctional enzyme (PBE) (... 41 0.030
UniRef50_Q8EYS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=4; L... 40 0.039
UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3; Achol... 40 0.039
UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1; A... 40 0.052
UniRef50_A3TT55 Cluster: Putative fatty acid oxidation complex a... 40 0.052
UniRef50_A1TEA9 Cluster: Putative uncharacterized protein; n=2; ... 40 0.052
UniRef50_Q4FL01 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; B... 40 0.069
UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65; cell... 40 0.069
UniRef50_Q8CXB6 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ... 39 0.091
UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|R... 39 0.091
UniRef50_A6LMV1 Cluster: Putative uncharacterized protein precur... 39 0.12
UniRef50_A5ZCW2 Cluster: Putative uncharacterized protein; n=1; ... 39 0.12
UniRef50_A3LNF8 Cluster: Kynurenine 3-monooxygenase, mitochondri... 39 0.12
UniRef50_Q83EI9 Cluster: Thiamine biosynthesis oxidoreductase Th... 38 0.16
UniRef50_Q6MHW5 Cluster: Glucose-inhibited division protein; n=1... 38 0.16
UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13; Baci... 38 0.16
UniRef50_Q2GH13 Cluster: FAD-dependent oxidoreductase; n=6; Anap... 38 0.21
UniRef50_Q13I86 Cluster: 3-hydroxybutyryl-CoA epimerase; n=11; B... 38 0.21
UniRef50_Q97PL8 Cluster: Oxidoreductase, pyridine nucleotide-dis... 38 0.28
UniRef50_Q0AI36 Cluster: 3-hydroxybutyryl-CoA epimerase; n=3; Ni... 38 0.28
UniRef50_A6TSA3 Cluster: Amine oxidase; n=1; Alkaliphilus metall... 38 0.28
UniRef50_A3XPY3 Cluster: Putative uncharacterized protein; n=1; ... 38 0.28
UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4; Thermococ... 38 0.28
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 38 0.28
UniRef50_P38169 Cluster: Kynurenine 3-monooxygenase; n=4; Saccha... 38 0.28
UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 37 0.37
UniRef50_Q485S6 Cluster: Putative D-amino acid dehydrogenase, sm... 37 0.49
UniRef50_Q490A1 Cluster: UDP-glucose 6-dehydrogenase; n=12; Stre... 37 0.49
UniRef50_Q128W2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 37 0.49
UniRef50_Q0TSZ8 Cluster: Transcriptional regulator, MarR family;... 37 0.49
UniRef50_Q1FP37 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 36 0.64
UniRef50_A3D4X7 Cluster: FAD dependent oxidoreductase; n=3; Shew... 36 0.64
UniRef50_A1SV61 Cluster: FAD dependent oxidoreductase precursor;... 36 0.64
UniRef50_Q6KCB6 Cluster: Dihydrolipoyl dehydrogenase; n=8; Plasm... 36 0.64
UniRef50_A7TI21 Cluster: Putative uncharacterized protein; n=1; ... 36 0.64
UniRef50_Q8RC01 Cluster: UDP-N-acetyl-D-mannosaminuronate dehydr... 36 0.85
UniRef50_Q82W31 Cluster: Phosphoribosylaminoimidazole carboxylas... 36 0.85
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 36 0.85
UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3; Cl... 36 1.1
UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid aminot... 36 1.1
UniRef50_Q8GP50 Cluster: Eps11H; n=13; Lactobacillales|Rep: Eps1... 36 1.1
UniRef50_A6M0T5 Cluster: Amine oxidase; n=6; Clostridium|Rep: Am... 36 1.1
UniRef50_A0UYP0 Cluster: Amine oxidase; n=1; Clostridium cellulo... 36 1.1
UniRef50_Q4J9Z6 Cluster: Conserved Crenarchaeal protein; n=3; Su... 36 1.1
UniRef50_Q8YKN8 Cluster: Zeta-carotene desaturase; n=4; Bacteria... 35 1.5
UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7; Bacte... 35 1.5
UniRef50_Q6MDA0 Cluster: Probable soluble pyridine nucleotide tr... 35 1.5
UniRef50_Q6FF29 Cluster: Putative oxidoreductase; putative flavo... 35 1.5
UniRef50_Q6A6B6 Cluster: Pyridine nucleotide-disulphide oxidored... 35 1.5
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 35 1.5
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;... 35 1.5
UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex,... 35 1.5
UniRef50_A7FX66 Cluster: Pyridine nucleotide-disulphide oxidored... 35 1.5
UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ac... 35 1.5
UniRef50_Q0CYI1 Cluster: Predicted protein; n=1; Aspergillus ter... 35 1.5
UniRef50_Q8TWI7 Cluster: UDP-N-acetylmuramoylalanine-D-glutamate... 35 1.5
UniRef50_Q9X0U4 Cluster: Glutamate synthase, beta subunit; n=5; ... 35 2.0
UniRef50_Q3AEV2 Cluster: Prephenate dehydrogenase; n=1; Carboxyd... 35 2.0
UniRef50_Q2RJ81 Cluster: 4Fe-4S ferredoxin, iron-sulfur binding ... 35 2.0
UniRef50_Q2JD10 Cluster: Prephenate dehydrogenase; n=4; Frankia|... 35 2.0
UniRef50_Q1MF67 Cluster: Putative D-amino acid dehydrogenase pre... 35 2.0
UniRef50_Q99ZM2 Cluster: D-lactate dehydrogenase; n=7; Streptoco... 35 2.0
UniRef50_Q4FKW7 Cluster: D-amino-acid dehydrogenase small chain;... 34 2.6
UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1; Mycop... 34 2.6
UniRef50_Q2LWM5 Cluster: Zinc-binding dehydrogenase; n=1; Syntro... 34 2.6
UniRef50_Q1IUZ3 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 34 2.6
UniRef50_Q1IMR6 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 34 2.6
UniRef50_Q1FMM1 Cluster: Dihydrolipoyl dehydrogenase; n=2; Clost... 34 2.6
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 34 2.6
UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1; ... 34 2.6
UniRef50_A5V9L0 Cluster: FAD dependent oxidoreductase precursor;... 34 2.6
UniRef50_A7RTC7 Cluster: Predicted protein; n=1; Nematostella ve... 34 2.6
UniRef50_P12045 Cluster: Phosphoribosylaminoimidazole carboxylas... 34 2.6
UniRef50_UPI0001597852 Cluster: hypothetical protein RBAM_031240... 34 3.4
UniRef50_Q9JXF8 Cluster: Glycine oxidase ThiO; n=4; Neisseria|Re... 34 3.4
UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8; My... 34 3.4
UniRef50_Q8R9D9 Cluster: Dihydrolipoyl dehydrogenase; n=3; Therm... 34 3.4
UniRef50_Q8F125 Cluster: Cell-division inhibitor; n=3; Bacteria|... 34 3.4
UniRef50_Q39TK4 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 34 3.4
UniRef50_Q4AI87 Cluster: FAD-dependent pyridine nucleotide-disul... 34 3.4
UniRef50_Q2BN82 Cluster: D-amino acid dehydrogenase, small subun... 34 3.4
UniRef50_Q0F8T2 Cluster: Salicylate hydroxylase; n=1; alpha prot... 34 3.4
UniRef50_A4XMY3 Cluster: Prephenate dehydrogenase; n=1; Caldicel... 34 3.4
UniRef50_A0M4X2 Cluster: Kynurenine-3-monooxygenase-like protein... 34 3.4
UniRef50_Q8TZS4 Cluster: Glutamate synthase; n=78; cellular orga... 34 3.4
UniRef50_Q5ZV78 Cluster: Mercuric reductase; n=5; Legionella pne... 33 4.5
UniRef50_Q31JD0 Cluster: Thiamine biosynthesis oxidoreductase; n... 33 4.5
UniRef50_Q0SA65 Cluster: Possible 3-hydroxybutyryl-CoA dehydroge... 33 4.5
UniRef50_Q0C0V2 Cluster: Oxidoreductase, FAD-binding; n=2; Prote... 33 4.5
UniRef50_Q0B0P7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 33 4.5
UniRef50_A3EPX8 Cluster: Dihydrolipoyl dehydrogenase; n=1; Lepto... 33 4.5
UniRef50_Q02670 Cluster: ORF22; n=1; Podospora anserina|Rep: ORF... 33 4.5
UniRef50_A5UMG8 Cluster: Cell wall biosynthesis protein, MurD-li... 33 4.5
UniRef50_A3DNK1 Cluster: Dihydrolipoamide dehydrogenase; n=1; St... 33 4.5
UniRef50_UPI0000510280 Cluster: COG1249: Pyruvate/2-oxoglutarate... 33 6.0
UniRef50_Q9FC18 Cluster: 2,4-dienoyl-CoA reductase [NADPH]; n=5;... 33 6.0
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 33 6.0
UniRef50_Q8G3X6 Cluster: Possible class I pyridine nucleotide-di... 33 6.0
UniRef50_Q87Q19 Cluster: D-amino acid dehydrogenase, small subun... 33 6.0
UniRef50_Q5H1Q2 Cluster: Putative uncharacterized protein; n=6; ... 33 6.0
UniRef50_Q5FJ98 Cluster: Peroxidase; n=8; Lactobacillales|Rep: P... 33 6.0
UniRef50_Q9JPB5 Cluster: Methoxyneurosporene dehydrogenase; n=5;... 33 6.0
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci... 33 6.0
UniRef50_Q021A6 Cluster: FAD-dependent pyridine nucleotide-disul... 33 6.0
UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 33 6.0
UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 6.0
UniRef50_A6CF61 Cluster: Soluble pyridine nucleotide transhydrog... 33 6.0
UniRef50_A4CCE3 Cluster: Putative D-amino acid dehydrogenase, sm... 33 6.0
UniRef50_A4A0Z6 Cluster: Putative transmemembrane reductase oxid... 33 6.0
UniRef50_A1HBS6 Cluster: 2-polyprenyl-6-methoxyphenol hydroxylas... 33 6.0
UniRef50_A0YKN9 Cluster: Putative secreted oxidoreductase; n=1; ... 33 6.0
UniRef50_A0YDQ2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 33 6.0
UniRef50_Q5CRF9 Cluster: Alpha amylase; n=2; Cryptosporidium|Rep... 33 6.0
UniRef50_O28680 Cluster: Putative uncharacterized protein; n=1; ... 33 6.0
UniRef50_P77212 Cluster: Probable pyridine nucleotide-disulfide ... 33 6.0
UniRef50_Q92A98 Cluster: Lin2024 protein; n=13; Listeria|Rep: Li... 33 7.9
UniRef50_Q8R5T2 Cluster: NADH:flavin oxidoreductases, Old Yellow... 33 7.9
UniRef50_Q8ESA1 Cluster: Phosphoribosylaminoimidazole carboxylas... 33 7.9
UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus pla... 33 7.9
UniRef50_Q5WI78 Cluster: NADH peroxidase; n=1; Bacillus clausii ... 33 7.9
UniRef50_Q5L3D7 Cluster: Phosphoribosylaminoimidazole carboxylas... 33 7.9
UniRef50_P73059 Cluster: Mercuric reductase; n=11; Bacteria|Rep:... 33 7.9
UniRef50_Q222Q6 Cluster: FAD dependent oxidoreductase precursor;... 33 7.9
UniRef50_Q1YK26 Cluster: Phosphoribosylaminoimidazole carboxylas... 33 7.9
UniRef50_Q1Q5P1 Cluster: Similar to NAD(P) oxidoreductase, FAD-c... 33 7.9
UniRef50_Q1NYB6 Cluster: FAD-dependent pyridine nucleotide-disul... 33 7.9
UniRef50_A7DM30 Cluster: Multi-sensor hybrid histidine kinase; n... 33 7.9
UniRef50_A7B6H9 Cluster: Putative uncharacterized protein; n=1; ... 33 7.9
UniRef50_A6SY70 Cluster: Uncharacterized conserved protein; n=2;... 33 7.9
UniRef50_A5Z4N7 Cluster: Putative uncharacterized protein; n=1; ... 33 7.9
UniRef50_A3PFJ2 Cluster: NAD binding site:D-amino acid oxidase; ... 33 7.9
UniRef50_A7PXU5 Cluster: Chromosome chr15 scaffold_37, whole gen... 33 7.9
UniRef50_Q2H005 Cluster: Putative uncharacterized protein; n=1; ... 33 7.9
UniRef50_A7EL57 Cluster: Putative uncharacterized protein; n=1; ... 33 7.9
UniRef50_A4YI59 Cluster: Pyridine nucleotide-disulphide oxidored... 33 7.9
UniRef50_P54533 Cluster: Dihydrolipoyl dehydrogenase; n=41; Firm... 33 7.9
UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 33 7.9
>UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA -
Drosophila melanogaster (Fruit fly)
Length = 315
Score = 277 bits (678), Expect = 2e-73
Identities = 131/204 (64%), Positives = 157/204 (76%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 223
K+EKVGIVGSGLIGRSW+MLFASVGYQV L+D++ +Q++ A+ + +L+ LE GLLRG
Sbjct: 4 KNEKVGIVGSGLIGRSWSMLFASVGYQVVLYDILPEQVSTALTATQKELQDLEAKGLLRG 63
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
L A +QF C+ GT DL VK AIFVQEC+PE L+LKK +++ LD VV NTI
Sbjct: 64 KLTAAQQFACISGTNDLKELVKGAIFVQECIPERLDLKKALYKQLDAVVGPNTILSSSTS 123
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
++K+KA V+VSHPVNPPYYVPLVEIVPAPWTKPE KKTRA+MEEIGQ+PV
Sbjct: 124 TFLPSLFSADLKNKANVLVSHPVNPPYYVPLVEIVPAPWTKPEWVKKTRALMEEIGQKPV 183
Query: 584 TLSREIDGFVLNRIQYAILGEVWR 655
TLSREI+GF LNRIQYAIL E WR
Sbjct: 184 TLSREIEGFALNRIQYAILNETWR 207
>UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to
3-hydroxyacyl-coa dehyrogenase; n=5; Coelomata|Rep:
PREDICTED: similar to 3-hydroxyacyl-coa dehyrogenase -
Strongylocentrotus purpuratus
Length = 316
Score = 233 bits (571), Expect = 2e-60
Identities = 106/204 (51%), Positives = 140/204 (68%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 223
+S+K+GIVGSGLIGRSWAM+FAS G+ VT+FD+ Q+++A+ IK QL+ L + G+LRG
Sbjct: 2 ESQKIGIVGSGLIGRSWAMIFASAGFSVTIFDIEPSQVSNALKLIKSQLEELSESGMLRG 61
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
L+ + QF +KG+ + A+ A FVQECV E LE+K+KVF ++ V D I
Sbjct: 62 TLSVEAQFALIKGSNSMEEALAGASFVQECVFEKLEVKQKVFSEMEQYVSDGAILSSSSS 121
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
EN+K + Q I+SHP+NPPYY PLVEI+PAPWT +TR IME +GQ PV
Sbjct: 122 CIMPSQFTENLKRRNQCIISHPINPPYYAPLVEIIPAPWTDQSAIDRTRTIMESVGQVPV 181
Query: 584 TLSREIDGFVLNRIQYAILGEVWR 655
TL +E+ GF NRIQYAI+ EVWR
Sbjct: 182 TLKKEVPGFAANRIQYAIIAEVWR 205
>UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30;
Coelomata|Rep: Lambda-crystallin homolog - Homo sapiens
(Human)
Length = 319
Score = 218 bits (532), Expect = 1e-55
Identities = 99/200 (49%), Positives = 141/200 (70%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V IVGSG+IGRSWAMLFAS G+QV L+D+ ++QI +A+ +I+ ++K LE+ G L+G+L+
Sbjct: 9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSV 68
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
+EQ + G ++ AV+ A+ +QECVPE+LELKKK+F LD+++DD I
Sbjct: 69 EEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMP 128
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+ H Q IV+HPVNPPYY+PLVE+VP P T P +T A+M++IGQ P+ + +
Sbjct: 129 SKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQK 188
Query: 596 EIDGFVLNRIQYAILGEVWR 655
E+ GFVLNR+QYAI+ E WR
Sbjct: 189 EVAGFVLNRLQYAIISEAWR 208
>UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 322
Score = 203 bits (495), Expect = 3e-51
Identities = 98/212 (46%), Positives = 136/212 (64%), Gaps = 3/212 (1%)
Frame = +2
Query: 29 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 208
M S + KV ++GSGLIGR+W+ LF+S GY V L+D V Q+ +A I QL+ LE
Sbjct: 1 MTSSTEKGKVAVIGSGLIGRAWSTLFSSAGYHVALYDTVSSQLVNAKEAIISQLQELESK 60
Query: 209 GLLRGN--LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDN- 379
LL+G A E F+ V T DL A+ +VQEC PENLELKKKVFQNL+ + +
Sbjct: 61 ELLKGRHCKTAQEAFKLVTTTDDLPQALNGVFYVQECTPENLELKKKVFQNLEATLSSSE 120
Query: 380 TIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIM 559
I E+++ + + IV+HP+NPPYYVPLVE++PAPWT V ++T +M
Sbjct: 121 VILASSTSCIMPSKFTESLQLRQRCIVAHPINPPYYVPLVEVIPAPWTDASVIEQTIKLM 180
Query: 560 EEIGQEPVTLSREIDGFVLNRIQYAILGEVWR 655
++IGQ PV L +E +GF++NR+QYA++ E WR
Sbjct: 181 KDIGQSPVLLKKETNGFIVNRLQYALIAEAWR 212
>UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|Rep:
LOC570274 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 327
Score = 190 bits (463), Expect = 3e-47
Identities = 96/207 (46%), Positives = 133/207 (64%)
Frame = +2
Query: 35 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGL 214
S K + + +VGSGLIGRSWAM+F S GY+V L+D Q + AIA+I+ QL+ L++ +
Sbjct: 14 SSLKEKIITVVGSGLIGRSWAMVFLSGGYKVKLYDNKPGQASGAIAEIRKQLEELQQAKM 73
Query: 215 LRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 394
LRGNL+A EQ + DL A+ A FVQE V E+LE K+ VF ++ +V ++ I
Sbjct: 74 LRGNLSATEQLSRLSSHEDLQQALDGAFFVQESVFEDLEAKQSVFHAVEELVSESVILSS 133
Query: 395 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQ 574
++++ + IVSHPVNPPYYV LVE+VP P T P V + ++M ++GQ
Sbjct: 134 STSCLMPSNVFSQVQNRTRCIVSHPVNPPYYVRLVELVPHPETLPAVMEVAYSLMTDVGQ 193
Query: 575 EPVTLSREIDGFVLNRIQYAILGEVWR 655
PV L +EIDGF LNR+QYAI+ E WR
Sbjct: 194 APVRLRKEIDGFALNRVQYAIIAESWR 220
>UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Proteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Acidiphilium cryptum (strain JF-5)
Length = 312
Score = 171 bits (417), Expect = 9e-42
Identities = 83/201 (41%), Positives = 126/201 (62%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
K+ +VG+GL+G +WA++FA G+ V ++D VE AI I +LKTLE+ GL+
Sbjct: 2 KIAVVGAGLVGSAWAIVFARAGHDVAVYDAVEGGADRAIGLIGDRLKTLEEVGLIEDAAA 61
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
A ++ V+ LA AV DA ++QE V E +E K+++F LD VV T+
Sbjct: 62 AGQR---VRVAASLADAVADAAYIQESVFETVEQKRQIFAALDAVVGPETLIGSSSSGIP 118
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+++ + + +++HPVNPPY +P+VE+VPAPWT ++ RA+ME +GQEPV L+
Sbjct: 119 ASAFTDHVGCRERCLIAHPVNPPYLIPVVELVPAPWTAAATVQRVRALMESVGQEPVELT 178
Query: 593 REIDGFVLNRIQYAILGEVWR 655
REI+GF LNR+Q +L E W+
Sbjct: 179 REIEGFALNRLQGLLLAEAWK 199
>UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Oceanicola granulosus HTCC2516
Length = 312
Score = 157 bits (380), Expect = 3e-37
Identities = 84/200 (42%), Positives = 115/200 (57%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KV I+G+GLIG+SWA+ FA G VTL D A+A + L LE+ LL G
Sbjct: 3 KVAIIGAGLIGQSWAIAFARGGCAVTLHDRDHAVADRALAVLPDALAALERMDLLGGE-T 61
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
AD + DLA AV+ AI VQE PE LE+K+ VF LD+ D + +
Sbjct: 62 ADAVGARIDAASDLADAVRGAIHVQENTPETLEVKRSVFAQLDDAADADAVIASSSSALL 121
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ + A+ +V+HP+NPP+ VP VE+VP P T E +TRA+M IGQ P+ S
Sbjct: 122 PSAFTDGLAGAARCLVAHPLNPPHLVPAVELVPGPQTSAETVARTRALMSSIGQSPIETS 181
Query: 593 REIDGFVLNRIQYAILGEVW 652
RE++GFV+NR+Q A+L E +
Sbjct: 182 REVEGFVMNRLQGALLDEAF 201
>UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5;
Alphaproteobacteria|Rep: Mll1034 protein - Rhizobium
loti (Mesorhizobium loti)
Length = 315
Score = 152 bits (368), Expect = 8e-36
Identities = 78/200 (39%), Positives = 115/200 (57%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V IVGSG IGR+WA+ FA G+ V ++D A I+ L L + LLRG +
Sbjct: 4 VAIVGSGFIGRAWAISFARAGHDVRMWDQSPAATGGARDYIEGVLGDLAANDLLRGQ-SV 62
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
D + DLA A+ DA VQE PENL++K++VF +D + TI
Sbjct: 63 DTVLGRIATVGDLAEALADAAHVQENTPENLDVKREVFSLIDRLAGPQTIIASSTSALLP 122
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
++++ + + +V HP+NPPY +P E+VPAPWT E +KTRA + + G P+ + R
Sbjct: 123 SKFTDHLQGRHRCLVVHPINPPYLIPAAEVVPAPWTSAETLEKTRAFLIDAGHAPLVMRR 182
Query: 596 EIDGFVLNRIQYAILGEVWR 655
E+DGF++NR+Q A+L E +R
Sbjct: 183 ELDGFIMNRLQGALLEEAFR 202
>UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Pseudomonas putida W619
Length = 320
Score = 148 bits (358), Expect = 1e-34
Identities = 80/214 (37%), Positives = 121/214 (56%), Gaps = 1/214 (0%)
Frame = +2
Query: 17 LRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT 196
+R +S + + IVG+GLIGR+WA++FA G+ V L D+ + + ++ A I+ +L
Sbjct: 1 MRTTASSATERGPIAIVGAGLIGRAWAIVFARAGHPVRLHDMDLQTMQNSHAYIEARLNE 60
Query: 197 LEKDGLLR-GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVD 373
L + LL L + CV DLA A++D + VQE V E +E K +F +D +
Sbjct: 61 LAEFDLLNDAPLTVLARITCVP---DLADALRDVVLVQENVRETVEAKIDIFSRMDALAP 117
Query: 374 DNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRA 553
+ I +++ + + +V+HP NPPY VPLVE+ PAPWT+ EV +
Sbjct: 118 KDAILASSTSWLPASEFTKDLPGRGRCVVAHPTNPPYLVPLVELCPAPWTESEVMVRAHE 177
Query: 554 IMEEIGQEPVTLSREIDGFVLNRIQYAILGEVWR 655
I GQ PV LSREI GF+LNR+Q A+L E ++
Sbjct: 178 IYTAAGQSPVVLSREIHGFLLNRVQAAVLNECFK 211
>UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 144 bits (350), Expect = 1e-33
Identities = 65/175 (37%), Positives = 106/175 (60%)
Frame = +2
Query: 131 LFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQE 310
++D+ EKQ+ A+ +++ L+ L++ GL RGNL+ADE V T L +K+AI++QE
Sbjct: 1 MYDISEKQLQVALENVEKNLRKLDEHGLQRGNLSADEALLRVSTTTSLNEVMKNAIYMQE 60
Query: 311 CVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYV 490
E+L + + ++ +D + D TI + + +K + ++ HPVNPP ++
Sbjct: 61 SALEDLNFRIQFYKVIDEIADPTTILASSTSTIPASKFTDGLINKERCLIVHPVNPPLFL 120
Query: 491 PLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREIDGFVLNRIQYAILGEVWR 655
PL E+VPAPWT + + IM + QEPV L +E+ GFV+NR+Q+A+L E WR
Sbjct: 121 PLTELVPAPWTSQDTVDRAAEIMRSVKQEPVKLKKEVLGFVVNRLQFALLAETWR 175
>UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain
protein; n=1; uncultured bacterium 582|Rep:
3-hydroxyacyl-CoA dehydrogenase domain protein -
uncultured bacterium 582
Length = 322
Score = 143 bits (346), Expect = 4e-33
Identities = 77/200 (38%), Positives = 114/200 (57%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V +VG+GLIG WA++FA G+QVTL D+ ++ A + VQL+ LE+ L
Sbjct: 17 VSVVGAGLIGCGWAIVFARAGWQVTLQDIDLAKLQGAPKVLAVQLRMLEQHDLCADPAGI 76
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
+ + DL AV + +VQEC PE L LK+++F LD + TI
Sbjct: 77 LAR---ISYESDLKTAVCEVDYVQECGPEVLGLKQELFSELDALTPPETILASSTSGLMA 133
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
++ + + +V+HPVNPP+ VP+VEI P+ WT PE+ + +M +GQ PVT+ +
Sbjct: 134 SQFSAHLAGRHRALVAHPVNPPHLVPVVEISPSEWTDPEIVRVVVDVMTGVGQTPVTVQK 193
Query: 596 EIDGFVLNRIQYAILGEVWR 655
EI GF+LNR+Q A+L E R
Sbjct: 194 EIPGFLLNRLQGALLNEALR 213
>UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Paracoccus denitrificans (strain Pd 1222)
Length = 311
Score = 137 bits (331), Expect = 2e-31
Identities = 74/200 (37%), Positives = 107/200 (53%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+ IVG+GLIGR+WA +FA G+ V ++D+ + + DI + G + +
Sbjct: 4 IAIVGAGLIGRAWAFVFARAGFDVRVWDLDPQVLERLDGDIAAMVAQTAPFG--QAGADP 61
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
D ++ DLA A+ A VQE PE L +K+++F LD + I
Sbjct: 62 DATAARIRAVPDLAGALDGAELVQESGPEVLAIKRELFARLDGLAAAGVILASSSSALMA 121
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
E + ++ +V HPVNPP+ VP+VEI PAP+T P +T + R I GQ PV L R
Sbjct: 122 SAFAEGLPGASRCLVGHPVNPPHLVPVVEIAPAPFTDPVITARARDIYARAGQVPVMLKR 181
Query: 596 EIDGFVLNRIQYAILGEVWR 655
EIDGF+LNR+Q +L E R
Sbjct: 182 EIDGFILNRLQAVVLAESLR 201
>UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Roseovarius sp. HTCC2601
Length = 316
Score = 126 bits (304), Expect = 5e-28
Identities = 67/199 (33%), Positives = 109/199 (54%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
K+ I+GSG+IG SWA+++A G V +++ E A+ ++ L + LLR
Sbjct: 5 KIAILGSGVIGASWAIVYARSGCDVAIYERSEAFRDSAMQRLESSLAS--SASLLRDGET 62
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
+ + L AV A FV EC+ ENL+ K+++F L++ + I
Sbjct: 63 VQDVLARITLHDTLEAAVAGADFVHECIVENLDSKRQIFAALNDAAEPEAILASTTSSFP 122
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
++ + + I+ HP PP+ +P+ EI PAP+T EV+++T A M E GQ PV +
Sbjct: 123 VSHFASDLACRDRCIIVHPATPPHLLPVTEICPAPFTSAEVSERTTAFMRECGQIPVRIK 182
Query: 593 REIDGFVLNRIQYAILGEV 649
+E++GFVLNR+Q A+L E+
Sbjct: 183 KEVEGFVLNRMQAALLVEM 201
>UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Roseobacter denitrificans OCh 114|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Roseobacter
denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 331
Score = 124 bits (300), Expect = 1e-27
Identities = 67/203 (33%), Positives = 108/203 (53%), Gaps = 4/203 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V I+G GLIG++WA +F G +VTL+D + A A + ++ R +L
Sbjct: 19 VAIIGCGLIGQAWATVFLRAGMRVTLYDAASGLVEQAKAQVIERMTEFA-----RFDLVT 73
Query: 236 DEQFQCVKGTCDLAIAVKDAI----FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
E + +LA ++DA+ ++QE E L++K ++ + +D + +
Sbjct: 74 HETLERAPAHIELADTLEDAVSAADYIQESGSEALDVKIELTREIDRFAAPHVVIGSSTS 133
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
E +K + + +V HP+NPP+ VPLVE+VPAPWT ++ IGQ P+
Sbjct: 134 GITASRYSETIKGRERCLVVHPINPPHLVPLVEVVPAPWTAQSAVDTVHDLLSAIGQVPI 193
Query: 584 TLSREIDGFVLNRIQYAILGEVW 652
L+REIDGFV+NR+Q A+L E +
Sbjct: 194 LLNREIDGFVVNRLQGALLREAF 216
>UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 330
Score = 124 bits (298), Expect = 2e-27
Identities = 76/207 (36%), Positives = 117/207 (56%), Gaps = 8/207 (3%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLLRG 223
KV I+G G IG SWA LF + G +V+ FDV E + + +A+ L +L GL++
Sbjct: 6 KVAIIGCGSIGASWAALFLAQGLEVSAFDVNPSAESFLRELVANALPVLSSL---GLVKS 62
Query: 224 N--LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 397
+ AD +F T D+A A+K+A FVQE PE L+ K+K+F+ + N+VD +TI
Sbjct: 63 SQATAADIEF-----TTDMATALKNASFVQENGPERLDFKQKLFRGVANLVDPDTIIATS 117
Query: 398 XXXXXXXXXXENMK--HKAQ-VIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEI 568
+ ++ HK + V+V HP NPP+ +PLVE+V T +T EE+
Sbjct: 118 SSGLTCSSIQQGLEAQHKPERVVVGHPFNPPHLIPLVEVVGGEQTSQATISRTMGFYEEV 177
Query: 569 GQEPVTLSREIDGFVLNRIQYAILGEV 649
G++ V + +E+ G V NR+Q A++ EV
Sbjct: 178 GKKAVHIKKEVVGHVANRLQAALMREV 204
>UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=3; Bordetella|Rep: Putative 3-hydroxyacyl-CoA
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 313
Score = 123 bits (297), Expect = 3e-27
Identities = 72/202 (35%), Positives = 109/202 (53%), Gaps = 2/202 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK-TLEKDGLLRGNLN 232
V ++G G+IG SWA++FA G +VT +VE+ +A + +L +E+ L G
Sbjct: 4 VAVIGGGIIGASWAVVFARRGLEVT---IVERDAA-CLAGLPARLAGMIERSASLLGAGE 59
Query: 233 ADEQFQCVKGTCD-LAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
G D LA AV A +VQE V ENL LK+ +F LD + + +
Sbjct: 60 QPGDVAARIGATDALAAAVGRADYVQEAVSENLALKRTLFAELDALAPAHALLASSTSTY 119
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
E + +A+ +V+HP+ PP+ P+VE+ + WT P+V A M +GQ PV +
Sbjct: 120 GASQFTEALAGRARCLVAHPMTPPHLSPVVEMAASAWTDPQVLAGAEAFMRSLGQHPVRI 179
Query: 590 SREIDGFVLNRIQYAILGEVWR 655
+EI GFVLNR+Q A+L E++R
Sbjct: 180 RKEIPGFVLNRLQGALLMEMFR 201
>UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Rhodobacterales bacterium HTCC2654
Length = 324
Score = 123 bits (296), Expect = 4e-27
Identities = 65/199 (32%), Positives = 107/199 (53%), Gaps = 1/199 (0%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITD-AIADIKVQLKTLEKDGLLRGNL 229
+V +G G +G WA +FA G++V L+D I A+ I+ L+ L ++ + G
Sbjct: 3 RVVCIGVGTVGCGWATVFARAGHEVVLYDADADAIAARALPRIEATLEQLGRE-MPTGET 61
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
AD + + ++ L A+ A VQE V E+L +K+ +F + D+ +
Sbjct: 62 PADIRAR-IRVAGSLEEALSGAEVVQESVREDLAIKRALFDEIGAAAPDDCLLLSSTSAL 120
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
++ H + +V HPVNPP ++PLVE+ P T PE ++ R E G EP+T+
Sbjct: 121 PGSQFLSDIPHPERALVGHPVNPPSHIPLVELCATPLTAPETVERARRFYTEAGMEPITV 180
Query: 590 SREIDGFVLNRIQYAILGE 646
++EIDGF+LNR+QY ++ E
Sbjct: 181 NKEIDGFILNRLQYTLVAE 199
>UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 -
Clostridium kluyveri DSM 555
Length = 319
Score = 119 bits (287), Expect = 5e-26
Identities = 65/199 (32%), Positives = 103/199 (51%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ V ++G+G +G L A G V +F + + IK LK LE+ G ++ N+
Sbjct: 4 KNVAVLGTGTMGNGIVQLCAESGLNVNMFGRTDASLERGFTSIKTSLKNLEEKGKIKTNI 63
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ E + +KG + AV+ FV EC+ E+LELK++VF LD + I
Sbjct: 64 SK-EILKRIKGVKTIEEAVEGVDFVIECIAEDLELKQEVFSKLDEICAPEVILASNTSGL 122
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
N KH +V+++H NPP ++PLVE+VP T + T +E IG++ V +
Sbjct: 123 SPTDIAINTKHPERVVIAHFWNPPQFIPLVEVVPGKHTDSKTVDITMDWIEHIGKKGVKM 182
Query: 590 SREIDGFVLNRIQYAILGE 646
+E GF+ NR+Q A+L E
Sbjct: 183 RKECLGFIGNRLQLALLRE 201
>UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=3; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 318
Score = 118 bits (283), Expect = 2e-25
Identities = 64/199 (32%), Positives = 110/199 (55%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+ IVG+G IG ++A+LFAS G V ++D + A +++ +L+ L K L +
Sbjct: 13 ISIVGAGSIGVAFAVLFASRGASVRIWDALPDAFDRAANELRSRLEMLAKASAL--SEPP 70
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
DE + +LA A+ A VQEC PEN++LK +F+ L ++ D+ +
Sbjct: 71 DEISSRISWHRNLAEALDGADLVQECAPENIDLKVDLFRWLADLTPDHVVLASSSSALIA 130
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+++ + +V+V HP NPPY +P++E+VP+P T + + I +PV + R
Sbjct: 131 SLIAPDIEIRRRVLVGHPGNPPYLIPVIEVVPSPETAQAIIDRAFEIYRNSHLKPVLVRR 190
Query: 596 EIDGFVLNRIQYAILGEVW 652
E++GF+ NR+Q A+L E +
Sbjct: 191 EVEGFIFNRLQGAVLREAY 209
>UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 315
Score = 115 bits (277), Expect = 9e-25
Identities = 66/200 (33%), Positives = 104/200 (52%), Gaps = 2/200 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KV +G+G +G SWA LFA G V ++D + + A A I + TL + + G+ +
Sbjct: 4 KVACIGAGTVGASWASLFAWRGCDVAVYDPFPEALNRAEASIARTVSTLSE--IFSGSED 61
Query: 233 -ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
VK T +L A+K A +VQE E LE+K+ +F+ +D + + TI
Sbjct: 62 DVKSALSRVKFTENLEEALKGAYYVQESAVEKLEVKRDLFEKMDAIAEPETILATSTSGL 121
Query: 410 XXXXXXENM-KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
KH + I +HP NPP+ +PLVE+VP T T+KT ME +G++P+
Sbjct: 122 SISEIQTAARKHPERCITAHPYNPPHLIPLVEVVPRKQTDESCTEKTVEFMERMGKKPIV 181
Query: 587 LSREIDGFVLNRIQYAILGE 646
+ +++ G V NR+ A+ E
Sbjct: 182 VKKDVPGMVANRLAAALWRE 201
>UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Planctomyces maris DSM 8797
Length = 311
Score = 113 bits (271), Expect = 5e-24
Identities = 63/202 (31%), Positives = 105/202 (51%), Gaps = 3/202 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ-LKTLEKDGLL--R 220
+++GI+G+GLIG SWA FA+ G +V +FDV + ++ VQ L+ L L+ +
Sbjct: 2 QEIGILGAGLIGASWATFFAAQGLRVRIFDV-NNTVKQQAQELSVQNLQRLADLELISRK 60
Query: 221 GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
A+E+ V +L + D +VQE V E+ E+K V+Q + + I
Sbjct: 61 DAATAEEKLNVVDSLAEL---LTDVEYVQESVIEDYEIKADVYQQFEQYAPEAAILGSSS 117
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
M+H + +++HP NPP+ +PLVE+VP T E + + + +G+ P
Sbjct: 118 SGLLMTRMQTVMQHPGRALIAHPFNPPHLIPLVELVPGEQTATETMETVKEFFQGLGKHP 177
Query: 581 VTLSREIDGFVLNRIQYAILGE 646
V L+RE+ G + NR+ A+ E
Sbjct: 178 VILNREVPGHIANRLAAAVWRE 199
>UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=1; Treponema denticola|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Treponema denticola
Length = 309
Score = 111 bits (268), Expect = 1e-23
Identities = 66/208 (31%), Positives = 108/208 (51%)
Frame = +2
Query: 29 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 208
M K K KV +VG G +G + +FA G+ V + + + + A+ IK+ L +
Sbjct: 1 MIEKGKKIKVAVVGDGTMGHGISEVFAKAGHTVQIIGLNDASLKSALDRIKLSLNEFVAE 60
Query: 209 GLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIX 388
GL+ + + D + + D+ A +DA V E +PEN++LK + F L+ + +TI
Sbjct: 61 GLVSAS-DIDTIVGRISFSTDIQKA-EDAAIVIEALPENMDLKTETFGKLEKICPQDTIL 118
Query: 389 XXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEI 568
+ +K + +VI +H PP +PLVE+ AP T T +++ I
Sbjct: 119 ATASGHSVSEVIAQ-VKKRDRVIATHFWFPPQLLPLVEVCGAPETSKATIDTTCELLKGI 177
Query: 569 GQEPVTLSREIDGFVLNRIQYAILGEVW 652
G++PV + +EIDGF+ NRIQ+A L E W
Sbjct: 178 GKKPVVIDKEIDGFIGNRIQFAALREAW 205
>UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 314
Score = 108 bits (259), Expect = 1e-22
Identities = 66/203 (32%), Positives = 105/203 (51%), Gaps = 6/203 (2%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V ++G+G IGRS+A LFA GY V +FD + + + +++ ++ + A
Sbjct: 5 VAVIGAGTIGRSFAWLFARSGYPVQVFDP-RPDLAEVVTELQAEVSA---------DAAA 54
Query: 236 DEQFQCVKGTCDLAIAVKDAI----FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+ GT LA +V+ A+ FVQE PE+ + K K+F + + I
Sbjct: 55 HDMLASELGTISLAESVETAVAGASFVQESGPEDPQAKPKLFAQIAAAAPKDAIFATSSS 114
Query: 404 XXXXXXXXENMKHK--AQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQE 577
++ + A+VIV HP NPP+ +PLVE+VPAP T + ++ G+E
Sbjct: 115 TIPASLIARHLPPEVAARVIVGHPFNPPHLMPLVEVVPAPATSSDTVERALEFYRSCGRE 174
Query: 578 PVTLSREIDGFVLNRIQYAILGE 646
PV L+RE+ GFV NR+Q A++ E
Sbjct: 175 PVALNREVRGFVGNRLQNALMKE 197
>UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1;
Brevibacterium sp. HCU|Rep: Hydroxyacyl-CoA
dehydrogenase - Brevibacterium sp. HCU
Length = 316
Score = 107 bits (257), Expect = 2e-22
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 1/200 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VGI G+G IG ++A+LFA G+ V +FD + + I ++ L++ LL N
Sbjct: 7 VGIFGAGSIGTAFALLFADAGFAVRIFDPDPSALERSRHVIDQRITELQRFTLLASN--P 64
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
E + ++ A AI VQE PE+++ K+ +F++L V D TI
Sbjct: 65 SEVRELIEIVSSARTAASGAILVQEAGPEDVQTKQHIFEDLTAVTSDETILASASSAIPS 124
Query: 416 XXXXENMKHKA-QVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ H A + ++ HP NPPY + +VE+V P T+ + + + E+ G V ++
Sbjct: 125 SRFVD--VHSAFRSLIGHPGNPPYLLRVVELVGNPSTEEQTILRAGQLYEQAGLSAVRVN 182
Query: 593 REIDGFVLNRIQYAILGEVW 652
RE+DGFV NRIQ A+L E +
Sbjct: 183 REVDGFVFNRIQGAVLREAY 202
>UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 311
Score = 107 bits (256), Expect = 3e-22
Identities = 69/202 (34%), Positives = 106/202 (52%), Gaps = 2/202 (0%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK-TLEKDGLLRGNL 229
KV I+G+G+IG +WA F + G+ VT FD + A A ++ Q++ LE G G++
Sbjct: 6 KVAILGTGVIGAAWATGFLTAGHTVTAFDPAD----GAEARLRSQVEGNLEVTG--EGDI 59
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ + G+ LA +V DA FVQE PE L++K+ + D+ V + I
Sbjct: 60 TSAMERLHFAGS--LAESVGDADFVQENGPERLDIKQSMLAETDSAVPASAIIASSTSGF 117
Query: 410 XXXXXXENM-KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
H +++V HP NP + VPLVE+VP P T EV K+ I IG++P+
Sbjct: 118 APSELATKATNHPERIVVGHPFNPAHLVPLVELVPTPATPAEVVKRGLEIYRSIGKKPIL 177
Query: 587 LSREIDGFVLNRIQYAILGEVW 652
+ E+ G V NR+Q A+ E +
Sbjct: 178 VRAELPGHVTNRLQAALWQEAY 199
>UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2;
Bifidobacterium longum|Rep: Possible butyryl-CoA
dehydrogenase - Bifidobacterium longum
Length = 319
Score = 107 bits (256), Expect = 3e-22
Identities = 63/196 (32%), Positives = 96/196 (48%)
Frame = +2
Query: 65 VGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADEQ 244
VG+G +G + + FA GY V L E + A+ I+ + + GLL+ D
Sbjct: 14 VGTGTMGHAITLQFALAGYPVHLVGRSEASLEKAMKAIRSDAEDFAEAGLLKAGDTVDTV 73
Query: 245 FQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXX 424
+ G D A V D FV E V ENL++KK V+ +++ + I
Sbjct: 74 LARITGYADYASGVADVDFVIESVAENLDVKKSVWTEVEHAAPKDAILSTNTSGLSPTAL 133
Query: 425 XENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREID 604
M H + +V+H NP +PLVE+VP T P+V T +M +IG++P + +E
Sbjct: 134 QSVMGHPERFVVAHFWNPAQLMPLVEVVPGEKTDPKVVDITFDLMAKIGKKPAKIKKESL 193
Query: 605 GFVLNRIQYAILGEVW 652
GFV NR+Q A+L E +
Sbjct: 194 GFVGNRLQLAVLREAF 209
>UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyacyl-CoA-dehydrogenase -
Sulfolobus solfataricus
Length = 324
Score = 107 bits (256), Expect = 3e-22
Identities = 59/199 (29%), Positives = 102/199 (51%), Gaps = 1/199 (0%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KV ++G+G+IG W L + GY+V L+ ++ + A+A + L L+ G++ N
Sbjct: 10 KVAVIGAGVIGVGWTTLLLAKGYKVNLYTEKKETLEKALAKVSAYLVNLKNLGMI--NEE 67
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
+ + G + A+ + FV E + E+ KK +F+ LD + + I
Sbjct: 68 PESYITNLTGITKIDDAIHNVDFVIEAIIEDYTAKKNLFKLLDTQLPQDIIIASSTSGLL 127
Query: 413 XXXXXENM-KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ M +H + +++HP NPP+ +PLVEIVP T E TR ME++ + V L
Sbjct: 128 MTEIQKAMIRHPERGVIAHPWNPPHLLPLVEIVPGEKTSKETVDLTREFMEKLDRVVVLL 187
Query: 590 SREIDGFVLNRIQYAILGE 646
+E+ GF+ NR+ +A+ E
Sbjct: 188 RKEVPGFIGNRLAFALFRE 206
>UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 317
Score = 105 bits (251), Expect = 1e-21
Identities = 63/197 (31%), Positives = 103/197 (52%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+G+VG+GL+G A A G++ + DV ++ + L L G +
Sbjct: 19 IGVVGTGLMGVGIATQSALHGHRTIVHDVDPARLASVAPKAQAVLDELIDAGRIDPAAK- 77
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
++ +L + + A FV E +PE LELK +++ L ++ D+ I
Sbjct: 78 QAALARIETHAELDV-MASAQFVIEAIPEVLELKHRLYAALTQLLADDAILASNTSGFHP 136
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
++ K + +++H NPP+ +PLVE+VP T PEVT++T A+M IG EPV L++
Sbjct: 137 DQLAAPLRAKDRFVIAHFWNPPHMIPLVEVVPGTATAPEVTQQTAALMSAIGMEPVVLAK 196
Query: 596 EIDGFVLNRIQYAILGE 646
I GFV NR+Q+A+L E
Sbjct: 197 AIPGFVGNRLQFAMLRE 213
>UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG00090.1 - Gibberella zeae PH-1
Length = 320
Score = 104 bits (249), Expect = 2e-21
Identities = 64/200 (32%), Positives = 99/200 (49%), Gaps = 1/200 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V IVG G+IG WA+LF S G +V + D + A +K L+ RGN
Sbjct: 8 VAIVGCGVIGMGWAVLFMSCGLKVIISDPAD----GAHESLKRYLEQARSFFEERGNF-- 61
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLD-NVVDDNTIXXXXXXXXX 412
D+ + D+ + + FVQE PE +E K+ + + LD N I
Sbjct: 62 DKLSSNYEFVDDILPLLPEVDFVQENGPERVEFKQSLMEKLDENTRPGVAIASSSSGLPS 121
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ K +++++ HP NPP+ +PLVE+VP P T +V A + +G++P+ L
Sbjct: 122 SAFIQKCKKDPSRILIGHPFNPPHLIPLVEVVPHPGTSSDVVSSALAFYKSLGKKPILLH 181
Query: 593 REIDGFVLNRIQYAILGEVW 652
+E+ GFV NR+Q AI E +
Sbjct: 182 QEVPGFVSNRLQAAINNEAY 201
>UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=17; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Silicibacter sp. (strain
TM1040)
Length = 491
Score = 104 bits (249), Expect = 2e-21
Identities = 68/207 (32%), Positives = 103/207 (49%), Gaps = 5/207 (2%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLL 217
++ I+G G+IG WA F G+ V +FD E++I D +A+ + L L L
Sbjct: 2 TKTAAIIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGDVLANARRSLPGLGNVALP 61
Query: 218 -RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 394
G+L+ E LA V+ +VQE VPE L+LK+KV+ L+ +
Sbjct: 62 PEGSLSYHET---------LAETVQGVDWVQESVPERLDLKQKVYAELEAHAPGGAVIGS 112
Query: 395 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQ 574
+ + AQ++V+HP NP Y +PLVE+V PE+ K +AI+ EIG
Sbjct: 113 STSGYKPSQLQDGFTNAAQIVVAHPFNPVYLMPLVEVVTTDVNTPEMIAKAKAIITEIGM 172
Query: 575 EPVTLSREIDGFVLNRIQYAILGE-VW 652
P+ L +EID V +R A+ E +W
Sbjct: 173 YPLHLKKEIDAHVADRFLEAVWREALW 199
>UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=16; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Silicibacter pomeroyi
Length = 487
Score = 103 bits (247), Expect = 4e-21
Identities = 64/202 (31%), Positives = 100/202 (49%), Gaps = 5/202 (2%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLL-RGNL 229
I+G G+IG WA F G+ V +FD E++I + +A+ + L L L G L
Sbjct: 6 IIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGEVLANARRSLPGLSDMPLPPEGKL 65
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ DL AV A ++QE VPE L+LK KV++++ D I
Sbjct: 66 SFH---------ADLGEAVTGAAWIQESVPERLDLKLKVYRSIQEACDPGAILGSSTSGF 116
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
E Q++V+HP NP Y +PL+E+V P PE+ ++ + IM +GQ P+ +
Sbjct: 117 KPSELQEGALRPGQIVVTHPFNPVYLLPLIELVTTPENSPEMIERAKEIMRGLGQFPLHV 176
Query: 590 SREIDGFVLNRIQYAILGE-VW 652
+EID + +R A+ E +W
Sbjct: 177 RKEIDAHIADRFLEAVWREALW 198
>UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 668
Score = 102 bits (244), Expect = 9e-21
Identities = 62/209 (29%), Positives = 108/209 (51%), Gaps = 1/209 (0%)
Frame = +2
Query: 5 PLQTLRVV-MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK 181
P + +V+ M + + + V ++G+GL+G A + A GY VT+ D+ ++ + + IK
Sbjct: 2 PRRVKQVINMDVRERIKTVAVLGAGLMGHGIAEVCAMAGYNVTMRDIKQEFVDRGMNMIK 61
Query: 182 VQLKTLEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLD 361
L LE+ G ++ +A+E +K T DL AVKDA V E VPE +E+KK+V++ +D
Sbjct: 62 ESLAKLEQKGKIK---SAEEVLSRIKPTVDLEEAVKDADLVIEAVPEVVEIKKQVWEEVD 118
Query: 362 NVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 541
+ + I + + H NPP + LVE++ T EV
Sbjct: 119 KLAKPDCIFTSNTSTMRITMLADFTSRPEKFAGLHFFNPPVLMRLVEVIRGEKTSDEVMD 178
Query: 542 KTRAIMEEIGQEPVTLSREIDGFVLNRIQ 628
++ IG+ PV + +++ GF++NR+Q
Sbjct: 179 LLVEFVKSIGKTPVRVEKDVPGFIVNRVQ 207
>UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Archaea|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Thermoplasma volcanium
Length = 659
Score = 100 bits (240), Expect = 3e-20
Identities = 60/191 (31%), Positives = 95/191 (49%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KV ++GSG++G A A GY V L D+ + + A A+I L L K G L
Sbjct: 5 KVTVIGSGIMGHGIAETIALAGYDVNLEDISDDVLAKAKAEIDASLDRLVKSGKLSDKTK 64
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
+ + +VKDA V E VPE L++K++VF LD ++ I
Sbjct: 65 VLGRIHYFTSIPE---SVKDADLVIEAVPEILDIKRQVFAQLDQSTKEDAILATNTSNIR 121
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
E +K K +V+ H NPP + LVE++ + +T+ EV + ++IG+ P+ +
Sbjct: 122 LTEIAEGVKKKGKVVGMHFFNPPVVLKLVEVIRSDYTEDEVFEAVYDFSKKIGKIPIKVY 181
Query: 593 REIDGFVLNRI 625
++ GFV+NRI
Sbjct: 182 KDTPGFVVNRI 192
>UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 313
Score = 100 bits (239), Expect = 3e-20
Identities = 61/202 (30%), Positives = 101/202 (50%)
Frame = +2
Query: 41 FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLR 220
F++ K+ +VG+G++G A L+A G+QV L+D +Q+ A I ++ L K+GL
Sbjct: 2 FENWKLLVVGAGVMGSGIAQLYACKGFQVALYDKFPEQLDRAKQLIANNMENLIKEGLAT 61
Query: 221 GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
A+ + +L A V E V EN ++K++ F LD + + I
Sbjct: 62 QE-EAERTKTLISYETELEKCAPQADLVLESVFENADVKRETFAQLDKLCASDCILCSNT 120
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
+ H + I++H NPP+ + LVE+V P T E K ++ + ++G+EP
Sbjct: 121 SASNIFEIAP-VSHPERQIITHYFNPPFIMDLVEVVMGPKTSDETLDKVKSFLIQVGKEP 179
Query: 581 VTLSREIDGFVLNRIQYAILGE 646
L + I GF++NRI AI E
Sbjct: 180 AVLKQYIPGFIVNRIATAITRE 201
>UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Myxococcus xanthus DK 1622|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Myxococcus xanthus
(strain DK 1622)
Length = 321
Score = 99.1 bits (236), Expect = 8e-20
Identities = 59/202 (29%), Positives = 100/202 (49%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+++G+VG G +G A+ A G QV L++ A A ++ L + GLL
Sbjct: 7 KRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERARAKLERDASLLVETGLLAPE- 65
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A ++ T LA A + V E +PE+L LK+++F+ LD + +T+
Sbjct: 66 QAPAAIGRIRRTTVLAEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLATNTTAL 125
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ +V+ +H P + +PLV+I+P T P+ + R +EE+G+ PV
Sbjct: 126 SVTAIARDCTRPERVLSAHYYLPAHLIPLVDIIPGEKTSPDAVETVRRFIEELGKSPVVF 185
Query: 590 SREIDGFVLNRIQYAILGEVWR 655
SR++ G V R+Q A++GE R
Sbjct: 186 SRDVPGSVGPRLQQALIGEAIR 207
>UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 323
Score = 98.7 bits (235), Expect = 1e-19
Identities = 64/202 (31%), Positives = 92/202 (45%), Gaps = 4/202 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGL-LR 220
+V ++G+G IG W LF + GY+V + +E I DA+ L +D L
Sbjct: 11 RVAVIGAGSIGLGWITLFLAHGYRVRVNSTRSNIETVIHDALRLFTPGLPGASRDPADLA 70
Query: 221 GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
G L + DL AV D VQE PENLE+K+ +F L+ T+
Sbjct: 71 GRLEIEP---------DLERAVADVAVVQENTPENLEIKQDLFARLEKHAAAGTLLLSST 121
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
M + + +IV HP NPP+ +PLVE+V + P+ +G+ P
Sbjct: 122 STMLPADLGARMDNPSHLIVGHPFNPPHVIPLVEVVGDTTSDPDAVSAAAEFYRSVGKTP 181
Query: 581 VTLSREIDGFVLNRIQYAILGE 646
V L R I F NR+Q A+L E
Sbjct: 182 VVLRRPIAAFAANRLQSALLQE 203
>UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 303
Score = 98.7 bits (235), Expect = 1e-19
Identities = 63/197 (31%), Positives = 98/197 (49%), Gaps = 2/197 (1%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
+VG+G IG WA LF++ G +V + D D +A + L + + R + D+
Sbjct: 1 MVGAGTIGLGWAALFSAHGLEVRITDP-----RDDLASVVGDAMPLLAESMGR---DPDQ 52
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
++ LA AV DA VQE PE LE K+ +F ++ +
Sbjct: 53 LLAGIEIADSLADAVSDADLVQENGPERLEFKQDLFADIARHAPPRAVLASSSSGIVASA 112
Query: 422 XXENMKHKA--QVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
E++ +++++HP NPP VPLVEIVP T+ VT+ A +G+ PV L +
Sbjct: 113 IAEHLPDDVAGRLLIAHPFNPPQVVPLVEIVPGERTEERVTEAATAFYTALGKTPVRLRK 172
Query: 596 EIDGFVLNRIQYAILGE 646
E+ GFV NR+Q A++ E
Sbjct: 173 EVPGFVANRLQSAVMRE 189
>UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Sulfolobus|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Sulfolobus solfataricus
Length = 384
Score = 97.9 bits (233), Expect = 2e-19
Identities = 61/202 (30%), Positives = 103/202 (50%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+K+G+VG+G +G A + A Y V++ D+ + A I L + G ++
Sbjct: 4 KKIGVVGAGTMGHGIAEVSALANYNVSVVDISWDFLNRAKERIMESLNKFYEKGQIKEK- 62
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
++ + ++ + + ++DA FV E VPE +ELK+KVF+ LD++ +T
Sbjct: 63 -PEDIMKRIEFSTSYDV-MRDADFVIEAVPEIIELKRKVFETLDSITPSHTFLASNTSSI 120
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
E K K ++I H NPP + LVEIVP+ +T E + T + +++ + PV L
Sbjct: 121 PISTIAEVTKRKEKIIGMHFFNPPPIMKLVEIVPSKYTSDETIEVTIDLAKKMNKIPVKL 180
Query: 590 SREIDGFVLNRIQYAILGEVWR 655
E+ GFV NRI ++ E R
Sbjct: 181 KVEVPGFVSNRIFLRLMQEACR 202
>UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN
full-length enriched library, clone:A230106J09
product:crystallin, lamda 1, full insert sequence; n=3;
Euarchontoglires|Rep: Adult male hypothalamus cDNA,
RIKEN full-length enriched library, clone:A230106J09
product:crystallin, lamda 1, full insert sequence - Mus
musculus (Mouse)
Length = 140
Score = 96.7 bits (230), Expect = 4e-19
Identities = 44/85 (51%), Positives = 67/85 (78%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V IVGSGLIGRSWAMLFAS G++V L+D+ ++QITDA+ +I+ ++K+LE+ G L+G+L+A
Sbjct: 9 VVIVGSGLIGRSWAMLFASGGFKVKLYDIEQQQITDALENIRKEMKSLEQSGSLKGSLSA 68
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQE 310
+ Q + G +LA AV+ A+ +Q+
Sbjct: 69 ERQLSLISGCGNLAEAVEGAVHIQQ 93
>UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=3; Staphylococcus|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 321
Score = 96.7 bits (230), Expect = 4e-19
Identities = 62/198 (31%), Positives = 91/198 (45%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
K +VG+G+IG W + G++V D E + +K E+ GL N
Sbjct: 2 KFAVVGTGVIGSGWITRMLAHGHEVIATDPSEGAYERMLTQVKQNWPYAEQMGLAE---N 58
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
A Q + T L AVKDA +QE VPE E+K V + +D
Sbjct: 59 AS--IQNLTFTPHLEEAVKDADHIQENVPEVEEIKDAVLKEIDFYAKPEATIGSSTSGIM 116
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
N+ H +++V+HP +P Y +PLVEIVP T E T K I E IG + + +
Sbjct: 117 PSELQANLSHPERLVVAHPFHPVYILPLVEIVPGKQTSEETTVKAEQIYESIGMDVLHVR 176
Query: 593 REIDGFVLNRIQYAILGE 646
EI+G + +R+ A+ E
Sbjct: 177 HEIEGHIADRLMEALWRE 194
>UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 317
Score = 96.7 bits (230), Expect = 4e-19
Identities = 63/201 (31%), Positives = 93/201 (46%), Gaps = 1/201 (0%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
++V ++G+G+IG SWA LF + G V DV + LE+ GL
Sbjct: 6 KRVAVIGTGVIGASWAALFLAKGLDVAATDVAPDAEARLRQYLDAAWPALEELGLAPAAS 65
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVD-DNTIXXXXXXX 406
A F T DLA AV A VQE PE ++ K+ ++ LD ++ D I
Sbjct: 66 RARLTF-----THDLAEAVAGAGLVQENGPERIDFKRTLYGQLDALLPPDVPIASSSSGL 120
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
H + ++ HP NPP+ +PLVEIV T + +K A +G+ +
Sbjct: 121 TMSEIQTGCPAHPERCVIGHPFNPPHLIPLVEIVSGAQTSEQTVEKVTAFYTSLGKRTIR 180
Query: 587 LSREIDGFVLNRIQYAILGEV 649
L +E+ G V NR+Q A+ EV
Sbjct: 181 LHKEVPGHVANRLQAALWREV 201
>UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6;
Bacillaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 287
Score = 96.3 bits (229), Expect = 6e-19
Identities = 65/201 (32%), Positives = 105/201 (52%), Gaps = 3/201 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
E++ +VGSG++GR A + A G+Q TL D+ ++Q+ A + ++ ++ + G+ RG L
Sbjct: 3 ERLVVVGSGVMGRGIAYVGAVGGFQTTLVDIKQEQLESA----QKEIASIFEQGVARGKL 58
Query: 230 NADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
E+ + + + DLA AV+DA V E VPE LELKK+VF+ +D +
Sbjct: 59 TDSERQEAEARLSYSLDLAAAVRDADLVIEAVPEKLELKKQVFETIDAHAPASCYFATNT 118
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
K +VI H NP + + LVEI+ T E + + E +G+E
Sbjct: 119 STMSPTEIGSFTKRPERVIAMHFFNPVHKMKLVEIIRGLETSDETAQVAKEAAERMGKET 178
Query: 581 VTLSREIDGFVLNRIQYAILG 643
V ++ E GFV +RI A++G
Sbjct: 179 VVVN-EFPGFVTSRIS-ALVG 197
>UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelotomaculum thermopropionicum SI|Rep:
3-hydroxyacyl-CoA dehydrogenase - Pelotomaculum
thermopropionicum SI
Length = 319
Score = 96.3 bits (229), Expect = 6e-19
Identities = 59/197 (29%), Positives = 94/197 (47%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+ I+G+G +G S A G V L DV + A I+ L + G +G
Sbjct: 7 LAIIGAGTMGHSIAAAALQHGVSVRLIDVSAPALETARRKIQSYLASAAGKGGGKGGAVP 66
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
++ ++A V A V E VPE L+LKK++F LD + + I
Sbjct: 67 GHLAGVLETCMEMAAGVTGADMVIEAVPEKLDLKKEIFAQLDKLCPPSVILATNTSGLPI 126
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+V+ +H P Y +PLVE+V + +T P+V T A ++ IG++PV + +
Sbjct: 127 TAIASAAARPERVLGTHFYMPAYLIPLVEVVCSDYTSPDVAGDTVAFLQSIGRKPVLVKK 186
Query: 596 EIDGFVLNRIQYAILGE 646
+I GF+ NR+Q+AI E
Sbjct: 187 DIPGFIGNRLQHAIARE 203
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 95.9 bits (228), Expect = 7e-19
Identities = 55/197 (27%), Positives = 95/197 (48%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+ I+G G +G A A G QV +DV I A + + V L+ G+ +
Sbjct: 5 IAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPSAGV 64
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
V+ T D+ AV A V E VPEN+ +K V++ +D ++ +TI
Sbjct: 65 GT----VRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPI 120
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
++ + +++ H NPP+ +P++E++ T P+ R ++ IG PV + +
Sbjct: 121 TKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIGLLPVVVKK 180
Query: 596 EIDGFVLNRIQYAILGE 646
++ GFV NR+ YA+L E
Sbjct: 181 DVPGFVENRVLYALLRE 197
>UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Burkholderia sp. 383|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 333
Score = 95.9 bits (228), Expect = 7e-19
Identities = 59/199 (29%), Positives = 97/199 (48%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
E VGI+G+G IG SWA LF + G +V ++D + ++ +LE+ GL R
Sbjct: 12 EVVGILGAGTIGASWAALFLAAGLEVDVYDPSPEGEAFVRDYVRHAWPSLERLGLARRGD 71
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+F AV A FVQE VPE +E+K +++ +++ +D I
Sbjct: 72 PGRLRFVATPEE-----AVARAQFVQESVPERIEIKHALYRRIEDHLDPRAIVCSSASGL 126
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
K+ + I+ HP NPP+ +PLVE++ T+P V + G+ + +
Sbjct: 127 LVKEMQAGWKNPGRFILGHPFNPPHLIPLVELLGNEKTEPGVLELAEQFYAACGKITIRV 186
Query: 590 SREIDGFVLNRIQYAILGE 646
++E+ G V NR+Q A+ E
Sbjct: 187 NKEVPGHVANRLQAALWRE 205
>UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=5; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Silicibacter pomeroyi
Length = 317
Score = 95.5 bits (227), Expect = 1e-18
Identities = 64/201 (31%), Positives = 91/201 (45%), Gaps = 3/201 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVT--LFDVVEKQITDAIADIK-VQLKTLEKDGLLRG 223
+V +G G IG WA F + GY VT L D E+ I D + L L GL G
Sbjct: 11 RVTSIGGGPIGGGWAAHFLARGYDVTSYLHDRAEEGAFRTILDTAWISLTAL---GLAPG 67
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
++ DL AV A F+QE PENL +K+ ++ L +V +N +
Sbjct: 68 -----ASLDRLRVVHDLDAAVAGAGFIQESAPENLAMKQALYHRLGRIVPENVVIGSSTS 122
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
N + + ++ HP NPPY +PLVEIV T P + G+ P+
Sbjct: 123 GLMMTDIQANCETPGRTVIGHPFNPPYLLPLVEIVGGERTDPAAVEWAGEFYRVAGKAPL 182
Query: 584 TLSREIDGFVLNRIQYAILGE 646
+ +EI GFV R+Q A+ E
Sbjct: 183 MMKKEIPGFVATRLQEALWRE 203
>UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 308
Score = 95.5 bits (227), Expect = 1e-18
Identities = 55/198 (27%), Positives = 100/198 (50%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KV ++G+G IG S+A + + + I D +D+ ++ G
Sbjct: 7 KVTLIGTGTIGLSFA------AFHLAKLSPSQLTIYDTRSDLSTYIEEFLPKFFESGKSP 60
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
AD ++ L AV D+ +QE PENL++K+K+++ ++ ++ +
Sbjct: 61 AD--LSEIRLAVTLQEAVSDSHIIQESGPENLDVKRKLWKEVEKYAPNDALLWSSTSGIP 118
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
++M+ K +++V HP NPP+ +PL+E+VP+ T V +T+ E G+ P+ +
Sbjct: 119 ASQQAQDMQDKTRLLVVHPYNPPHIMPLLELVPSSETSDTVISRTQDFWRERGRVPIHIK 178
Query: 593 REIDGFVLNRIQYAILGE 646
RE GFV NR+ +A+L E
Sbjct: 179 RETTGFVANRLAFALLRE 196
>UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24;
Burkholderia|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 305
Score = 95.1 bits (226), Expect = 1e-18
Identities = 58/201 (28%), Positives = 101/201 (50%), Gaps = 1/201 (0%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
++ IVG+G+IG SWA + + G+ V D + AD +++ G L+
Sbjct: 5 RIAIVGAGVIGASWAAFYLTQGFDVVATDPAPQ------ADTRLRESLAAFLGERAAELS 58
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNT-IXXXXXXXX 409
A F DL A+ FVQE PE L+LK+ +++ +D+V+ + I
Sbjct: 59 ARLSFDA-----DLVRALDGVDFVQENGPERLDLKRALYRQMDDVLPAHVPIASSSSGLK 113
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
KH + +++HP NPP+ +PLVE+V T +VT + + + +G++ + L
Sbjct: 114 MSDIQTACDKHPERCLIAHPFNPPHLIPLVELVGGDATSQDVTARVKDFYDALGKQTIVL 173
Query: 590 SREIDGFVLNRIQYAILGEVW 652
++E+ G V NR+ A+ EV+
Sbjct: 174 NKEMTGHVANRLAAALFREVY 194
>UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
NAD-dependent; n=9; Clostridiales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase NAD-dependent -
Clostridium perfringens
Length = 282
Score = 94.3 bits (224), Expect = 2e-18
Identities = 60/199 (30%), Positives = 94/199 (47%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
EK+ ++G+G +G FA GY+V + D+ ++ + IA I L L G +
Sbjct: 2 EKIFVIGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVDRGIAGINKGLTKLVSKGKITEE- 60
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ + + GT DL +A D V E EN+E+KK++F LD + + TI
Sbjct: 61 DKEAVLSKITGTTDLGLAA-DCDLVIEAAVENMEIKKQIFAELDKICKEETILASNTSSL 119
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+VI H NP + LVE++ T E K +A+ E IG+ PV +
Sbjct: 120 SITEVASATNRPDRVIGMHFFNPATIMKLVEVIRGMATSQETFDKVKAMSEAIGKTPVEV 179
Query: 590 SREIDGFVLNRIQYAILGE 646
+ E GFV+NRI ++ E
Sbjct: 180 A-EAPGFVVNRILIPMINE 197
>UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=8; Mycobacterium tuberculosis complex|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Mycobacterium tuberculosis
Length = 304
Score = 93.1 bits (221), Expect = 5e-18
Identities = 61/198 (30%), Positives = 103/198 (52%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+ +VG+GL+GR A + AS G V + D +I A A ++ G RG++
Sbjct: 9 RAAVVGAGLMGRRIAGVLASAGLDVAITDT-NAEILHAAA-----VEAARVAGAGRGSVA 62
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
A DLA A+ DA V E V ENL +K+++F+ L + D +
Sbjct: 63 A---------AADLAAAIPDADLVIEAVVENLAVKQELFERLATLAPD-AVLATNTSVLP 112
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
E ++ ++VI +H NPP +P+VE+VP+ T P+ + A++ ++G+ PV +
Sbjct: 113 IGAVTERVEDGSRVIGTHFWNPPDLIPVVEVVPSARTAPDTADRVVALLTQVGKLPVRVG 172
Query: 593 REIDGFVLNRIQYAILGE 646
R++ GF+ NR+Q+A+ E
Sbjct: 173 RDVPGFIGNRLQHALWRE 190
>UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precursor;
n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
precursor - Pseudomonas putida W619
Length = 313
Score = 93.1 bits (221), Expect = 5e-18
Identities = 60/197 (30%), Positives = 107/197 (54%), Gaps = 2/197 (1%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
++G+GL+G A +FA G++V+L+D T +A +V L++ G+ + A+
Sbjct: 9 VIGAGLMGHGIAQVFAQAGHKVSLYD--PDAATLDLAPQRVA-HNLDQMGIASAPILAN- 64
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
+ DL AV +A V E VPE LELK+K+F ++ +T+
Sbjct: 65 ----IALFTDLREAVSNADIVIEAVPERLELKQKLFADIAGFAPPHTVLASNTSVIPITE 120
Query: 422 XXENM--KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
E + + +A+++ +H NPP+ VPLVE+V T V + T +++ +G+ PV ++R
Sbjct: 121 IGEMLGSEARARLVGTHWWNPPHLVPLVEVVRTEHTSLSVFESTFELLQSLGKSPVKVNR 180
Query: 596 EIDGFVLNRIQYAILGE 646
++ GF+ NR+Q+A+ E
Sbjct: 181 DVAGFIGNRLQHAMWRE 197
>UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Bacillus sp. SG-1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bacillus sp. SG-1
Length = 293
Score = 92.3 bits (219), Expect = 9e-18
Identities = 63/201 (31%), Positives = 103/201 (51%), Gaps = 3/201 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+K+ ++GSG++GR A + A G+Q TL DV ++Q+ A + +L ++ + G+ RG L
Sbjct: 13 DKLVVIGSGVMGRGIAYVSAVGGFQTTLVDVEQRQLDSA----QGELTSIFQKGVDRGKL 68
Query: 230 NADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
+ +E + + D+A AV+ A V E VPE E+KK VF+ +D ++
Sbjct: 69 SKEESTDAQGRLSFSTDMAKAVESADLVIEAVPEKTEIKKAVFEKIDEYAQESCYFATNT 128
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
+VI H NP + +PLVEIV T E T+ + +G+E
Sbjct: 129 STMSPTEIASFTGRPKKVIAMHFFNPVHKMPLVEIVRGLETSDETTQFAENAAKRMGKET 188
Query: 581 VTLSREIDGFVLNRIQYAILG 643
V ++ E GFV +RI A++G
Sbjct: 189 VVIN-EFPGFVTSRIS-ALVG 207
>UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Ignicoccus hospitalis KIN4/I|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Ignicoccus hospitalis KIN4/I
Length = 683
Score = 91.9 bits (218), Expect = 1e-17
Identities = 61/203 (30%), Positives = 98/203 (48%), Gaps = 5/203 (2%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KV +VG+G++G A + A G V + D+ ++ + A+ IK L+ L G L+
Sbjct: 25 KVLVVGAGVMGHGIAQVAAMSGLNVRMIDIKQEFLDRAMERIKESLEKLYAKGKLKEPPE 84
Query: 233 AD-EQFQCVKGTCD----LAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 397
++ + + D A A KD FV E VPE LELK+ VF LD + I
Sbjct: 85 EVLKRIETMVANPDDESSYAEAAKDVDFVIEAVPEKLELKRAVFSVLDKYAPPHAILASN 144
Query: 398 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQE 577
+ K +V+ H NPP + LVE+V T E K T + +++G+
Sbjct: 145 TSSIPITEIAKATKRPDKVVGMHFFNPPVILKLVEVVRGKETSDETVKITVELAKKMGKV 204
Query: 578 PVTLSREIDGFVLNRIQYAILGE 646
P+ +++++ GF++NRI L E
Sbjct: 205 PIVVNKDVPGFIVNRIMARFLNE 227
>UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD binding
domain; n=2; Gammaproteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, C-terminal:3-hydroxyacyl-CoA
dehydrogenase, NAD binding domain - Azotobacter
vinelandii AvOP
Length = 307
Score = 91.1 bits (216), Expect = 2e-17
Identities = 59/195 (30%), Positives = 95/195 (48%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
I+G+GL+G A A G+ V L D +++ + L L G D
Sbjct: 8 ILGAGLMGIGIATHLARHGHAVLLRDPAAERLAEVPVMAGSILAELADAGRFE-RAQTDA 66
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
+ + LA V DA + E +PE LELK+ ++ L+ +V T+
Sbjct: 67 TLARLAVSPRLA-DVADARLLIEAIPERLELKRALYAELEALVGTGTVIASNTSGLPPDA 125
Query: 422 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREI 601
E M+H +++++H NPP+ +PLVEIVP T+ E + R ++ + E V L + I
Sbjct: 126 LAEGMRHPERLLIAHFWNPPHLIPLVEIVPGSATRAEHLEAVRTLLAGMELEAVVLDKAI 185
Query: 602 DGFVLNRIQYAILGE 646
GF+ NR+Q+A+L E
Sbjct: 186 PGFIGNRLQFAVLRE 200
>UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Marinomonas sp. MED121|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Marinomonas sp. MED121
Length = 323
Score = 91.1 bits (216), Expect = 2e-17
Identities = 56/199 (28%), Positives = 96/199 (48%), Gaps = 1/199 (0%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KVG++G+G+IG +WA+ + +G +V +D + + T+EK GL G
Sbjct: 12 KVGVIGTGVIGGAWALHYLRMGMEVVAYDPGPNSKEKLLTMVDNIWPTIEKLGLREGA-- 69
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
+ ++ + V LA V+ +QE PE L+ K+ +F +LD +V + +
Sbjct: 70 SKDKLRFVDSLDALANQVE---VIQESTPERLDAKRSLFADLDCIVPADVVIISSTSGFA 126
Query: 413 XXXXXENMKHKA-QVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
++ + + +V HP NPPY VP E+ T EV T A E ++ +
Sbjct: 127 MTDMANELETQPDRFVVGHPFNPPYLVPFCEVCGGERTSQEVVDWTAAFYEATEKQVAKM 186
Query: 590 SREIDGFVLNRIQYAILGE 646
+E+ GF+ NR+Q A+ E
Sbjct: 187 DKELPGFIGNRLQEALWRE 205
>UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 281
Score = 90.2 bits (214), Expect = 4e-17
Identities = 61/192 (31%), Positives = 88/192 (45%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
+E + ++G+G++G A A VG V L+DV E + + +A + L+ K G L
Sbjct: 2 AETIAVIGAGVMGSGIAQTAAMVGKTVYLYDVSEAALQNGLASAEKSLRRFVKTGGL-SE 60
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
A ++ T DLA AV+ A V E VPENL LKK VFQ LD + + I
Sbjct: 61 PEARAALGRIRSTVDLAEAVRGADVVIEAVPENLALKKDVFQQLDQLAKPDAILATNTSE 120
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
VI H NP + L+EIV T + R + E+G+E V
Sbjct: 121 LSVTALAAATNRPENVIGMHWFNPAPVMKLIEIVKGETTSDDTVDAIRRLSVELGKETVV 180
Query: 587 LSREIDGFVLNR 622
+ ++ GFV R
Sbjct: 181 V-KDRQGFVTTR 191
>UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Archaea|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Sulfolobus acidocaldarius
Length = 657
Score = 88.6 bits (210), Expect = 1e-16
Identities = 56/191 (29%), Positives = 93/191 (48%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+VG+VG+G +G A + A G+ V L DV E + +A+ I+ L+ L + ++ N N
Sbjct: 6 RVGVVGAGTMGHGIAEVVAIAGFNVVLTDVNEDILRNALEKIRWSLEKLREKRQIKENPN 65
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
+K T D F+ E E ++K+K+F LD VV + I
Sbjct: 66 T--VLSRIKTTVSFG-DFSDVDFIIEAAIERSDVKRKIFSELDRVVKKDAIFATNTSTIP 122
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
E + + I H +NPP +PLVEI+ T E K T + ++I ++ V +
Sbjct: 123 ISYLAEVTGRQEKFIGLHFMNPPVLMPLVEIIMGNKTAEETLKTTIDLAKKINKDYVVVK 182
Query: 593 REIDGFVLNRI 625
+++ GF++NRI
Sbjct: 183 KDVPGFLINRI 193
>UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 661
Score = 88.2 bits (209), Expect = 2e-16
Identities = 55/190 (28%), Positives = 93/190 (48%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V ++G+G +G + A + A G+ V L DV E Q+ A+ I+ L+ + G + + +
Sbjct: 9 VAVIGAGSMGHAIAEVVAIHGFNVKLMDVSEDQLKRAMEKIEEGLRKSYERGYI--SEDP 66
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
++ + ++ T DL KDA V E +PE +LKKKVF ++ D+TI
Sbjct: 67 EKVLKRIEATADLIEVAKDADLVIEAIPEIFDLKKKVFSEIEQYCPDHTIFATNTSSLSI 126
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
E K + I H NPP + L+EIV T E + +I + + + +
Sbjct: 127 TKLAEATKRPEKFIGMHFFNPPKILKLLEIVWGEKTSEETIRIVEDFARKIDRIIIHVRK 186
Query: 596 EIDGFVLNRI 625
++ GF++NRI
Sbjct: 187 DVPGFIVNRI 196
>UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;
n=3; Rhodobacteraceae|Rep: Putative hydroxlacyl-CoA
dehydrogenase - Sulfitobacter sp. NAS-14.1
Length = 309
Score = 87.8 bits (208), Expect = 2e-16
Identities = 57/200 (28%), Positives = 91/200 (45%), Gaps = 3/200 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLLRGN 226
V ++G GLIG SWA LF G+ V +D +A QL+ + +G
Sbjct: 7 VAVIGCGLIGASWAALFQHAGHTVRAWDPDTGARDGFAARVAGPLAQLQEISAGAAPQGA 66
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
L+ E Q A++D + +QE PEN+ LK +++ ++++V + I
Sbjct: 67 LSTHESLQD---------ALQDVVLIQENAPENVPLKHQLYAQIESIVAPDVIIASSTSA 117
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
M+H ++I +HP NPP+ VPLVE+ P T V +G PV
Sbjct: 118 HPWSDLVPGMQHPDRLITAHPFNPPHLVPLVEVY-GPDT--NVLDWAEGFYRSLGSVPVR 174
Query: 587 LSREIDGFVLNRIQYAILGE 646
L ++ G + NR+ A+ E
Sbjct: 175 LKKDAVGHIANRLSSALWRE 194
>UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Acinetobacter
baumannii (strain ATCC 17978 / NCDC KC 755)
Length = 233
Score = 87.0 bits (206), Expect = 3e-16
Identities = 37/118 (31%), Positives = 65/118 (55%)
Frame = +2
Query: 299 FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNP 478
F+QE PE L+LK+ ++Q + + + T+ ++ H ++ + HP NP
Sbjct: 6 FIQENAPERLDLKQNLYQEITSYCPEKTLIASSSSGLKVSDFQKDATHPERIFLGHPFNP 65
Query: 479 PYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREIDGFVLNRIQYAILGEVW 652
P+ +PLVEIV T P++ KK + +G+ P+ L++E+ G V NR+Q A+ E +
Sbjct: 66 PHLLPLVEIVGGKLTDPQILKKASEFYQSLGKHPIVLNKEVKGHVANRLQAALWREAF 123
>UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=2; Thermoplasmatales|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Thermoplasma acidophilum
Length = 291
Score = 86.6 bits (205), Expect = 5e-16
Identities = 57/190 (30%), Positives = 94/190 (49%), Gaps = 3/190 (1%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK---VQLKTLEKDGLLRGNLN 232
+VGSG++G+ A +FA GY VT+ DV + + +A+ IK L L K G + +
Sbjct: 8 VVGSGVMGQGIAQVFARSGYPVTIIDVRDDILANAVRSIKEGRYGLMNLVKKGTMTES-E 66
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
D+ ++ + ++ DA V E VPENL+LK+KVF +++ V +N I
Sbjct: 67 VDKIMGKIRTSTSYG-SLSDADIVVEAVPENLDLKRKVFIDIEKNVSENAIIASNTSGIT 125
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+++K K + I H NP + L+E+V A T + IG+ PV ++
Sbjct: 126 IAEIAQDLKKKDRAIGMHWFNPAGIMKLIEVVRAKMTSEDTISTVVDFSRRIGKTPVVVA 185
Query: 593 REIDGFVLNR 622
++ GF R
Sbjct: 186 -DVPGFFTTR 194
>UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Caulobacter sp. K31
Length = 348
Score = 86.2 bits (204), Expect = 6e-16
Identities = 60/199 (30%), Positives = 95/199 (47%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ V ++G+GL+G A +FA+ GY V LFD T A I + ++ G
Sbjct: 47 QPVAVLGAGLMGAGIAKVFAAKGYPVFLFDRDLDTATSATRQINGAIAHVD------GGR 100
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ D LA AV DA FV E V E L++K+++F L + +
Sbjct: 101 DVD-------AAGSLAEAVADAAFVFESVSEKLDVKRRIFSALAECARHDAVLASNTSAI 153
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
E + +A+++ SH NP VPLVE+VP T + ++ +G++ V +
Sbjct: 154 PITQIAEGLPCEARIVGSHWWNPADVVPLVEVVPGIATDAHHVEAMMQLLISVGKKAVRI 213
Query: 590 SREIDGFVLNRIQYAILGE 646
R+I GFV NR+Q+A+ E
Sbjct: 214 DRDIPGFVGNRLQFALWRE 232
>UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Halobacteriaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 669
Score = 86.2 bits (204), Expect = 6e-16
Identities = 53/200 (26%), Positives = 93/200 (46%), Gaps = 1/200 (0%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTL-EKDGLLRGN 226
+ + ++G+G +G + A GY V + D+ ++ + D +I+ L L E+D L +
Sbjct: 22 DTIAVLGAGNMGHGITEVAALAGYDVRMRDIKDEFVEDGYDNIEWSLNKLAERDQLTQEE 81
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
AD V D+ AV D V E VPE +E+KK V+ ++ +N I
Sbjct: 82 --ADAALDRVTPLVDVEEAVSDVDVVIEAVPEKMEIKKDVYTEVEEHAPENAIFATNTSS 139
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
E + Q H NPP + LVE++ + + + A+ E+ G+ PV
Sbjct: 140 LSITELSEVTERPEQFCGMHFFNPPVRMQLVEVISGAHSGDDTLEAIEALAEDFGKTPVR 199
Query: 587 LSREIDGFVLNRIQYAILGE 646
+ ++ GF++NRI ++ E
Sbjct: 200 VRKDSPGFIVNRILVPLMNE 219
>UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4;
Trichocomaceae|Rep: RIB40 genomic DNA, SC009 -
Aspergillus oryzae
Length = 337
Score = 85.8 bits (203), Expect = 8e-16
Identities = 60/213 (28%), Positives = 95/213 (44%), Gaps = 14/213 (6%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL-- 229
V I+G+G+IG SW LF + G +V + D + + Q TL + GL G
Sbjct: 12 VAIIGTGVIGASWTALFLARGLKVLVTDPAPNAEKNLETYLNAQWPTLTQIGLSEGASLK 71
Query: 230 ------NADEQFQCVKGTCDLAIAVKDA----IFVQECVPENLELKKKVFQNLDNVVDDN 379
+ D F+ + ++ + + V + PE LE K+ +F LD
Sbjct: 72 NYAFVDSLDNHFEEIDFIQEVPFPFSNTGVILLTVTKNGPERLEFKRTLFAYLDEKARPE 131
Query: 380 TIXXXXXXXXXXXXXXENMKHKAQ-VIVSHPVNPPYYVPLVEIVPAPWTKPE-VTKKTRA 553
I +H + V+V HP NPP+ +PLVE+VP T E V +
Sbjct: 132 VIIASSSSGIPSSEYASACRHHPERVLVGHPFNPPHLIPLVEVVPHRTTDRETVVPRAME 191
Query: 554 IMEEIGQEPVTLSREIDGFVLNRIQYAILGEVW 652
+G++PV + +EI GF+ NR+Q A+ E +
Sbjct: 192 FYRSLGKKPVLIQKEIPGFIANRLQAALSMEAY 224
>UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-coA dehydrogenase -
Clostridium tetani
Length = 282
Score = 84.6 bits (200), Expect = 2e-15
Identities = 57/199 (28%), Positives = 93/199 (46%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+K+ ++G+G +G A FA+ GY+V L D+ ++ + I I+ L L G +
Sbjct: 2 KKICVLGAGTMGAGIAQAFAAKGYEVVLRDIKDEFVERGIKGIEKGLSKLVSKGRM-AQE 60
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ D ++GT DL A D V E EN+E+K+++F LD + TI
Sbjct: 61 DMDSILGRIEGTVDLNKAA-DCDLVVEAAIENMEIKREIFAELDRICKPETILSSNTSSL 119
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+VI H NP + L+EI+ T E + + IG++PV +
Sbjct: 120 SITEIATATNRPDKVIGMHFFNPAPVMKLIEIIRGMATSQETFDAVKEVSVAIGKDPVEV 179
Query: 590 SREIDGFVLNRIQYAILGE 646
+ E GFV+NRI ++ E
Sbjct: 180 A-EAPGFVVNRILIPMINE 197
>UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 287
Score = 84.2 bits (199), Expect = 2e-15
Identities = 59/199 (29%), Positives = 91/199 (45%), Gaps = 1/199 (0%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGNLNAD 238
+VG+G +G AM+ A G+QV L DV + A +++ ++ + +EK ++ A
Sbjct: 6 VVGAGAMGSQIAMVCALAGHQVCLHDVDPAMLERADRELRDRMARQVEKGRRTADDVTAA 65
Query: 239 EQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXX 418
+ V + A A DA V E V E +E+K ++F LD + TI
Sbjct: 66 FERLRVADSLAAAAAAADADLVIEAVVERIEVKSELFAELDRLCPPATILASNSSSFVPS 125
Query: 419 XXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSRE 598
+V H NP + VE+VP P T + ++E +G+ PV L +E
Sbjct: 126 RLAAATGRADRVCNLHFFNPALVMACVEVVPGPETSGQTVASCVDLVESLGKVPVVLEKE 185
Query: 599 IDGFVLNRIQYAILGEVWR 655
I GFV NRI A+ E R
Sbjct: 186 IPGFVANRILNAVRDEAIR 204
>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bordetella parapertussis
Length = 354
Score = 83.8 bits (198), Expect = 3e-15
Identities = 56/199 (28%), Positives = 90/199 (45%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ + +VG+G +G A LFAS G+ V L D + +T A I+ QL D +
Sbjct: 50 QNLAVVGAGAMGSGIAALFASKGFDVVLIDPMAGALTRAAQVIERQLGVYAPDAIAPA-- 107
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
Q ++ L A A V E VPE L LK+ +F LD + D I
Sbjct: 108 -----MQRIRMDAGLEAACS-AQLVIEAVPEKLALKRDIFARLDTLCDPQAIFATNTSGL 161
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ + + + + +H P +PLVE+V T + + ++ G+ PV +
Sbjct: 162 SINDIAQAVTRRDRFVGTHFFTPADVIPLVEVVRNDDTSEQTVARVMGMLRAGGKRPVLV 221
Query: 590 SREIDGFVLNRIQYAILGE 646
++I GF+ NRIQ+A+ E
Sbjct: 222 RKDIPGFIANRIQHALARE 240
>UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Halobacteriaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 654
Score = 83.8 bits (198), Expect = 3e-15
Identities = 52/197 (26%), Positives = 92/197 (46%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V ++G+G +G A + A GY V L D+ + D +I+ L+ L + G L + +
Sbjct: 11 VAVLGAGTMGHGIAEVAAIAGYDVVLRDIDAAIVEDGYDEIEWSLEKLAEKGRL--DEDP 68
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
D+ V T DL AV DA V E PE L +K+ +F+++D + +
Sbjct: 69 DDVAARVATTTDLEAAVSDADLVIEAGPEQLSVKQDIFESVDAAAPADALLATNSSSLSI 128
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+ V+ H NPP + LVE++ T E ++ +E +G+ P+ + +
Sbjct: 129 TEIAAATERPESVLGLHFFNPPVKMDLVEVIYGKATTDETAQRGYEFIESLGKTPIYVRK 188
Query: 596 EIDGFVLNRIQYAILGE 646
++ GFV+N + + E
Sbjct: 189 DVRGFVVNSVLGPFMSE 205
>UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome.
precursor; n=6; Pezizomycotina|Rep: Contig An11c0270,
complete genome. precursor - Aspergillus niger
Length = 599
Score = 83.4 bits (197), Expect = 4e-15
Identities = 62/202 (30%), Positives = 94/202 (46%), Gaps = 1/202 (0%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
S + ++G+G++GR A +FA+ GY V L+D A+ + LKT K +GN
Sbjct: 12 SRPLALLGAGVLGRRIACVFAAAGYNVNLYDPSLSAQQAALDYVTQNLKTYSK--FSKGN 69
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
+F + DL V DA V E VPE+L++K V LD + + I
Sbjct: 70 ----RRFGHCRAFSDLESTVSDAWLVIEAVPEHLQMKIDVMGELDKLAPVDCILASNSSS 125
Query: 407 XXXXXXXENMK-HKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
E + H+ ++ + P +VE++ T PEV ++E++G PV
Sbjct: 126 FKSRFMLEKVGGHRRPLVCNMHFYMPPEKRVVELMTDGETWPEVFPFLTRVLEDVGMVPV 185
Query: 584 TLSREIDGFVLNRIQYAILGEV 649
T RE GFV NR+ AI EV
Sbjct: 186 TARRESTGFVFNRLWAAIKREV 207
>UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=48; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Burkholderia mallei
(Pseudomonas mallei)
Length = 331
Score = 83.0 bits (196), Expect = 6e-15
Identities = 56/209 (26%), Positives = 85/209 (40%)
Frame = +2
Query: 20 RVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTL 199
R MA K + +G+G+IG W + G V +D E A+++ L
Sbjct: 8 RKYMAVITKIDTFAAIGAGVIGSGWVARALANGLDVLAWDPAEDAEMQLRANVENAWPAL 67
Query: 200 EKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDN 379
E+ GL G A F C V DA FVQE PE LK ++ + + +
Sbjct: 68 ERAGLAPGASPARLHFVPTIEAC-----VADADFVQESAPEREALKLELHERISRAAKPD 122
Query: 380 TIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIM 559
I + IV HP NP Y +PLVE++ T P+ I
Sbjct: 123 AIIASSTSGLLPTDFYARAHRPERCIVGHPFNPVYLLPLVEVLGGERTAPDTVDAALGIY 182
Query: 560 EEIGQEPVTLSREIDGFVLNRIQYAILGE 646
+G P+ + +E+ GF+ +R+ A+ E
Sbjct: 183 RALGMRPLRVRKEVPGFIADRLLEALWRE 211
>UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Firmicutes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus sp. NRRL B-14911
Length = 295
Score = 82.6 bits (195), Expect = 7e-15
Identities = 56/199 (28%), Positives = 88/199 (44%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ + +VG+G +G AML A G++ TL D+ EK + A ++ + G L
Sbjct: 8 KNITVVGAGQMGHQIAMLCALGGFETTLHDMQEKALDQAQEKLRGIMDKWAAKGKLPSE- 66
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ F ++ T D AVK A F+ E V E LE+K++VF L+ + + I
Sbjct: 67 QIEAAFSRLRCTSDFGEAVKSADFIIEAVVEKLEVKREVFSMLEEMAPPHAIFATNSSTI 126
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ + H PP + VE+V + T E + + I + V L
Sbjct: 127 VNSLLANAADRPEKTVNMHFFFPPLVMDCVEVVMSSRTSEETAETAMEVCNAINRTAVLL 186
Query: 590 SREIDGFVLNRIQYAILGE 646
+EI GFV NRI A+ E
Sbjct: 187 KKEISGFVANRILGALQRE 205
>UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Roseovarius sp. HTCC2601
Length = 220
Score = 82.6 bits (195), Expect = 7e-15
Identities = 55/203 (27%), Positives = 99/203 (48%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
S ++ +VG+G +G A L+A GY + D + + D V+ GL+ +
Sbjct: 13 SGRICVVGAGFMGCVIATLYAHHGYDAVICDSNQTML-----DTYVERARPIAAGLVEDS 67
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
++ V DLA A++ V E V E+LE+K+ +F L+ + +N +
Sbjct: 68 DASEAMLAGVTLEPDLASAIEGVFLVHEAVQESLEVKQALFAELERICPENVVLATNTSS 127
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
M K +++ H V P + VP++E++ A T E+ +R +++ I V
Sbjct: 128 FLISDIAAQMTRKERMMGIHYVTPGHIVPVIELIHAADTPAELVAWSRMLVQNIEHVGVA 187
Query: 587 LSREIDGFVLNRIQYAILGEVWR 655
+ E GF++NRIQ+A+L E++R
Sbjct: 188 IL-ERPGFLVNRIQFAMLTEIYR 209
>UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding
- Halorubrum lacusprofundi ATCC 49239
Length = 676
Score = 82.6 bits (195), Expect = 7e-15
Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 1/200 (0%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 226
++V ++G+G +G A + A GY V L D+ E+ + I+ L K EKD + G
Sbjct: 20 QRVTVLGAGNMGHGIAEVAALAGYDVALRDIEEEFVQGGYDQIEWSLGKLAEKDRI--GE 77
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
AD V+ DL ++ DA V E VPE + +KK V+ + + +
Sbjct: 78 DEADAALDRVEAFVDLEDSLADADVVVEVVPEKMAIKKDVYDEVVEYAPEEAVFVTNTSS 137
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
E + H NPP + LVE++ T + + + E +G+ PV
Sbjct: 138 LSITELSEVTDRPERFCGMHFFNPPVRMDLVEVISGKHTSEDTLELIEGLAESMGKTPVR 197
Query: 587 LSREIDGFVLNRIQYAILGE 646
+ ++ GF++NRI ++ E
Sbjct: 198 VRKDSPGFIVNRILVPLMNE 217
>UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase; n=19;
cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase -
Aeropyrum pernix
Length = 669
Score = 82.2 bits (194), Expect = 1e-14
Identities = 56/206 (27%), Positives = 102/206 (49%), Gaps = 7/206 (3%)
Frame = +2
Query: 29 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 208
MA + K+ + +VG+G +G A L A G++V L D+ + +A+ I+ L+ L +
Sbjct: 1 MAGEVKT--ITVVGAGTMGHGIAELAAIAGFKVYLADINIDILNNALQRIRWSLEKLAEK 58
Query: 209 GLLRGN----LNADEQFQCVKG---TCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNV 367
G +R + ++ V+ + DLA A+ ++ F+ E +PE LELK+++F D
Sbjct: 59 GRIRESVETVMSRITPIVSVRDGEYSEDLAKALSESDFMIEAIPEKLELKQQLFAFADKH 118
Query: 368 VDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 547
+ I +V+ H NPP +PLVE+V T E T
Sbjct: 119 AKETAILASNTSSLPITEIAAATSRPEKVVGMHFFNPPVLMPLVEVVKGEKTSEETVAAT 178
Query: 548 RAIMEEIGQEPVTLSREIDGFVLNRI 625
+ +++G++ V + +++ GF++NRI
Sbjct: 179 VDLAKKMGKQTVVVKKDVPGFIVNRI 204
>UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Rep:
Blr6087 protein - Bradyrhizobium japonicum
Length = 330
Score = 81.8 bits (193), Expect = 1e-14
Identities = 59/208 (28%), Positives = 98/208 (47%), Gaps = 8/208 (3%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQI-------TDAIADIKVQLKTLEKDGL 214
+ +G+G +GR A+ FA G++VT+ DV + TDA+ +++ +L GL
Sbjct: 7 IACLGAGRMGRGIAVAFAYAGHRVTMIDVKPRSAEDFAKLETDALGEVRKTFASLSNLGL 66
Query: 215 L-RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 391
L +++ V A+ DA V E VPE +ELK++V V +TI
Sbjct: 67 LTEADVDPLVARVSVATASQSGTALADAGMVFEGVPEVVELKREVLGAASRQVKPDTIIA 126
Query: 392 XXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIG 571
+ + + + H +NP Y +PLVE+ P T P + + +A++E IG
Sbjct: 127 STTSTILVDDLSGAIVNPHRFLNVHWLNPAYLIPLVEVSPGKATDPAIIDEVKALLEGIG 186
Query: 572 QEPVTLSREIDGFVLNRIQYAILGEVWR 655
+ PV + GF++ RIQ + E R
Sbjct: 187 KVPVVCA-ATPGFIVPRIQALAMNEAAR 213
>UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Flavobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Dokdonia donghaensis MED134
Length = 394
Score = 81.4 bits (192), Expect = 2e-14
Identities = 57/205 (27%), Positives = 100/205 (48%), Gaps = 3/205 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ +GI+G+G +G A + A+ G V LFDV ++ + A ++ LK L + +G +
Sbjct: 3 KNIGIIGAGTMGSGIAQVAATAGCAVKLFDVNQEALDKAKEALEKVLKRL----IEKGRI 58
Query: 230 NADEQFQCVKGTCDLAIAVKD---AIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
+A E+ + ++ +K+ A E + ENLE+KKKVFQ L+ V D I
Sbjct: 59 DASEKDR-IQANITYVTTLKELANADLTIEAIVENLEVKKKVFQELETYVSDTAIIASNT 117
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
++++ + I H NP + LVE++PA T V A + ++
Sbjct: 118 SSLSIASIAASLQNPERCIGIHFFNPAPLMKLVEVIPAVQTSQNVLDTCVAEITR-WKKV 176
Query: 581 VTLSREIDGFVLNRIQYAILGEVWR 655
V ++++ GF++NR+ GE R
Sbjct: 177 VAIAKDTPGFIVNRVARPFYGEALR 201
>UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase; n=4; Crenarchaeota|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase - Cenarchaeum
symbiosum
Length = 365
Score = 81.4 bits (192), Expect = 2e-14
Identities = 47/182 (25%), Positives = 84/182 (46%)
Frame = +2
Query: 80 IGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADEQFQCVK 259
+G A + A+ GY+V L D+ ++ + A+ I+ L + G + D ++
Sbjct: 1 MGHGIAQVSAASGYEVVLRDIEQRFLDSAMEKIRWSLDKMASKGRITAE-EKDGILNRIR 59
Query: 260 GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMK 439
L A++ A V E VPE ++LK+KV+ LD + +
Sbjct: 60 PVVALGEALEGADLVIEAVPEVMDLKRKVYAELDAAAPEGAAFASNTSTLPITEIAQATS 119
Query: 440 HKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREIDGFVLN 619
+ I H NPP + LVE++P T E T+ T +E +G++ V +++ GF++N
Sbjct: 120 RPERFIGIHFFNPPQLMKLVEVIPGEGTSDETTRMTLEYVESLGKQAVLCRKDVPGFIVN 179
Query: 620 RI 625
R+
Sbjct: 180 RL 181
>UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Burkholderiales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 304
Score = 81.0 bits (191), Expect = 2e-14
Identities = 57/198 (28%), Positives = 99/198 (50%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+V ++G+GL+G A+ F + + V ++D V Q +A+ + + LE G RG
Sbjct: 10 RVAVLGAGLMGHGIALAFMTSDFDVAIWDPVS-QAREAVRERIAE--HLELMGDPRG--- 63
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
D V+ L V+D V E PE++ K+++ + +D +V+ I
Sbjct: 64 VD-----VRVCSTLQDCVRDCDIVVEAAPESVSTKRELIREID-LVNSECIIASNTSVLR 117
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
E +V+ +H NPPY +PLVE+V T+ V K+ + + G+ PV +
Sbjct: 118 ITEIAEGSADPGRVVGTHWWNPPYLMPLVEVVRGELTREGVAKQVSQWLSKAGKTPVDVY 177
Query: 593 REIDGFVLNRIQYAILGE 646
R++ GFV NR+Q+A++ E
Sbjct: 178 RDVPGFVGNRMQFALVRE 195
>UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 288
Score = 81.0 bits (191), Expect = 2e-14
Identities = 54/200 (27%), Positives = 100/200 (50%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
+ ++ + G+G++GR A++ A G++V+L+D A AD+ + N
Sbjct: 3 ASQISVFGAGIMGRGIAVVLADAGHRVSLYD--------ARADVAREAAAAHP------N 48
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
+ A + + AV+ + + E V ENLE+K+ +F ++ ++T
Sbjct: 49 IEASDTIEA---------AVEGSSLLFEAVVENLEVKRDLFAEIERF-SESTPIASNTST 98
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+N+ +++++H NP VPLVE+VP+P T+P+V + + G+ V
Sbjct: 99 FTPSELAKNLCEPGRLVIAHFFNPAEVVPLVEVVPSPDTRPDVVSAVTSALVAAGKTVVP 158
Query: 587 LSREIDGFVLNRIQYAILGE 646
L+RE GFV NR+Q A++ E
Sbjct: 159 LNREAPGFVANRLQAALVRE 178
>UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like
protein; n=1; marine actinobacterium PHSC20C1|Rep:
3-hydroxyacyl-CoA dehydrogenase-like protein - marine
actinobacterium PHSC20C1
Length = 288
Score = 81.0 bits (191), Expect = 2e-14
Identities = 54/195 (27%), Positives = 87/195 (44%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
K+ +VGSG +G L A G V +FDV E + A A + L+ + + +
Sbjct: 5 KLAVVGSGTMGHGIGQLAAMQGIAVRVFDVDEVALDRARASVATSLERFVRKETITDAQS 64
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
+ Q + + T DL A+ E VPE L LK+KVF +LD +
Sbjct: 65 HEIQGR-MDWTTDLDAALVGVEAAIEAVPEVLALKQKVFTDLDERTGPEVMLATNTSQLS 123
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ KH +V+ H NPP + LVEI+ T E+ ++ +++G+E +
Sbjct: 124 ITTIASSAKHPERVVGMHFFNPPVVMRLVEIIRGTMTSDEMLQRAIDFSDQLGKENIVCQ 183
Query: 593 REIDGFVLNRIQYAI 637
R+ GF+ R A+
Sbjct: 184 RDTPGFITTRAIMAL 198
>UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=31;
Proteobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 518
Score = 80.6 bits (190), Expect = 3e-14
Identities = 56/200 (28%), Positives = 92/200 (46%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VG++G+G +G A + A+ G+ V L+D+ E A+A I+ Q L + G L A
Sbjct: 20 VGVIGAGAMGAGIAQVAAAAGHTVLLYDLNEAACDKALAGIRAQFARLAEKGRLE-PAQA 78
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
D ++ +LA A+ V E E L++K+++F L+ VDD +
Sbjct: 79 DAAGARIRAVRELADFAGAALIV-EAAAERLDVKREIFATLERHVDDACLLATNTSSISI 137
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
++ +V H NP + LVE+V T PEV + A G+ PV +++
Sbjct: 138 TSIAAGLRVPQRVAGLHFFNPAPLMALVEVVSGLATAPEVAQVLYATAAAWGKRPV-MAK 196
Query: 596 EIDGFVLNRIQYAILGEVWR 655
GF++NR+ E R
Sbjct: 197 STPGFIVNRVARPYYAEALR 216
>UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 322
Score = 80.2 bits (189), Expect = 4e-14
Identities = 56/204 (27%), Positives = 86/204 (42%), Gaps = 4/204 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V +G G+IG W F G V L D A A I+ + G A
Sbjct: 13 VAAIGGGVIGGGWVAAFLGSGRAVRLHDPAP----GAEARIRAHVTQAWPQMAALGLARA 68
Query: 236 DEQFQCVKGTCDLAIAVKDAI----FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
D+ + G ++DA+ FVQE PE ++K+ +F LD +V + +
Sbjct: 69 DDDWT---GRLSFHETIEDAVEGTDFVQENTPERSDVKRALFAELDRLVPADVLVGSSTS 125
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ A+ ++ HP NP + +PLVE+ T P A +G+EPV
Sbjct: 126 SLPISDLQAGLSTAARFVLGHPFNPVHLIPLVEVGGGDATDPAAVDTALAFYAALGKEPV 185
Query: 584 TLSREIDGFVLNRIQYAILGEVWR 655
L+RE+ G + NR+ A+ E R
Sbjct: 186 RLNREVFGHIGNRLTSAMFREAVR 209
>UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 485
Score = 79.4 bits (187), Expect = 7e-14
Identities = 56/203 (27%), Positives = 95/203 (46%), Gaps = 3/203 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+G++G+G +G A + A+ G++V LFDV + +L TL K G + A
Sbjct: 11 IGVIGAGTMGAGIAQVAAAAGHKVLLFDVASGAAASGLERTAKELATLVKRGKME-QKRA 69
Query: 236 DEQFQCVKGTCDLAIAVKD---AIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
+E + G +A ++D A E + E L++K+KVF L+ ++ ++ I
Sbjct: 70 EE----IIGRITIAEKLEDLAPAALTVEAIVERLDVKQKVFAQLEAILAEDAILATNTSS 125
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+K +++ H NP + LVE+V T PEV + T A G+ V
Sbjct: 126 ISITAIGAALKRPERLVGMHFFNPAPIMKLVEVVSGLATSPEVAQITHATARAWGKTAVH 185
Query: 587 LSREIDGFVLNRIQYAILGEVWR 655
+ + GF++NR+ A GE R
Sbjct: 186 V-KSTPGFIVNRVARAFYGEPLR 207
>UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=3; Geobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Geobacter sp. FRC-32
Length = 289
Score = 79.4 bits (187), Expect = 7e-14
Identities = 56/190 (29%), Positives = 93/190 (48%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VG+ G+G +G A + A G QV + D+ E+ A I L+ + K G +
Sbjct: 9 VGMAGAGSMGAGIAQIAAMAGLQVKVVDMSEEVWGRAKKTIVKSLERVVKKGTITEK-EM 67
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
+E + + D+A ++KD F+ E V E++ +KK++F LD V D+TI
Sbjct: 68 EETLGRISFSTDVA-SLKDVPFIFEAVFEDINVKKELFAKLDAVCGDDTIYATNTSSISI 126
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+K+ A I H NP + LVE++PA T P + ++IG+ +T +
Sbjct: 127 TEMAALVKNPANFIGMHFFNPVPVMKLVEVIPALQTAPATKDLALEMAKKIGKTAIT-CK 185
Query: 596 EIDGFVLNRI 625
+ GFV+NR+
Sbjct: 186 DTPGFVVNRL 195
>UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 301
Score = 78.6 bits (185), Expect = 1e-13
Identities = 56/201 (27%), Positives = 91/201 (45%), Gaps = 1/201 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VG+VGSGL+G A + A GY V L D+ E + A+ I L L + G L +
Sbjct: 10 VGVVGSGLMGSGIAQVAAVAGYAVRLHDIEESALHRALTTIDESLHRLARKGKLS---TS 66
Query: 236 DEQFQCVKGTCDLAIA-VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
D + + T +A + D+ V E V E L++K+ VF L +V N +
Sbjct: 67 DVEAAKARITTTRRLADLADSDVVVEAVYEELDVKRVVFAELAAIVRPNVLLASNTTAIP 126
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ +V+ H +P + L EIV T + + R E +G+ + ++
Sbjct: 127 ITHIASGVSGPQRVVGMHFFSPVPVMQLCEIVRGLQTDDDTVARARRFAESLGKTCIVVN 186
Query: 593 REIDGFVLNRIQYAILGEVWR 655
R++ GFV +R+ A + E R
Sbjct: 187 RDVAGFVTSRLLVAFVNEALR 207
>UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=2; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Jannaschia sp. (strain CCS1)
Length = 466
Score = 78.2 bits (184), Expect = 2e-13
Identities = 63/205 (30%), Positives = 94/205 (45%), Gaps = 5/205 (2%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLL-R 220
K I+G G+IG WA F G+ V ++D E++I + + + + L L L
Sbjct: 2 KTAIIGGGVIGGGWAARFLLNGWNVAIYDPDPEAERKIGEVMDNARRALPGLYDTALPPE 61
Query: 221 GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
G L + T DL AV DA +VQE VPE L++K KV L + +
Sbjct: 62 GTL---------RFTDDLGDAVGDADWVQESVPERLDIKHKVHAELTTLAPGRAVIGSST 112
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
E A+VIV+HP NP Y +PL+E+V + K I+ IG P
Sbjct: 113 SGFKPSELTEK---GARVIVAHPFNPVYLLPLIELV----GDTDHCAKAAEILRGIGMYP 165
Query: 581 VTLSREIDGFVLNRIQYAILGE-VW 652
+ + +EID + +R A+ E +W
Sbjct: 166 LHVRKEIDAHIADRFLEAVWREALW 190
>UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a; n=3;
Magnetospirillum|Rep: Glyoxysomal fatty acid
beta-oxidation multifunctional protein MFP-a -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 703
Score = 77.8 bits (183), Expect = 2e-13
Identities = 60/194 (30%), Positives = 95/194 (48%), Gaps = 3/194 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KVGI+G+G +G AM FA++G VT+ DV ++ + + I+ K E+ + RG+L
Sbjct: 296 KVGIIGAGTMGGGIAMCFANIGIPVTIIDVSDENLQRGLGVIR---KNYERS-VSRGSLT 351
Query: 233 ADE---QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
++ + + + D A A+KDA E V E +ELKK +F LD V+ I
Sbjct: 352 QEQLESRMGLLSASTDYA-ALKDADLAIEAVFEKMELKKDIFAKLDAVLPAGAILGTNTS 410
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
K A VI H +P +PL+EIV T +V T M ++ ++
Sbjct: 411 TLDIDEIANTTKRPADVIGLHFFSPANVMPLLEIVQGKQTAMDVL-LTALDMAKLIKKTG 469
Query: 584 TLSREIDGFVLNRI 625
+S+ GF+ NR+
Sbjct: 470 VVSKVCYGFIGNRM 483
>UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
unidentified eubacterium SCB49|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - unidentified eubacterium SCB49
Length = 403
Score = 77.4 bits (182), Expect = 3e-13
Identities = 54/202 (26%), Positives = 96/202 (47%), Gaps = 2/202 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDGLLRGN-L 229
+GI+G+G +G A + A+ G V LFD+ + + A A + K+ + +EK +
Sbjct: 20 IGIIGAGTMGSGIAQVAATAGCTVKLFDLNQAALDKAKASLEKIMTRLVEKGRVTEEEKA 79
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
E V +LA D+ E + E+L +KKKVFQ L++ V D+ I
Sbjct: 80 RIQENISYVNALKELA----DSDLTIEAIIEDLGIKKKVFQELESYVSDSCIIASNTSSL 135
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+++ + + H NP + LVE++PA T V K + ++ ++ V +
Sbjct: 136 SIASIASSLQKPERCVGIHFFNPAPLMKLVEVIPAIQTSDAVLKISEETIKS-WKKVVAV 194
Query: 590 SREIDGFVLNRIQYAILGEVWR 655
+++ GF++NR+ GE R
Sbjct: 195 AKDTPGFIVNRVARPFYGEALR 216
>UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Sulfolobaceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Metallosphaera sedula DSM 5348
Length = 334
Score = 77.0 bits (181), Expect = 4e-13
Identities = 49/195 (25%), Positives = 103/195 (52%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KV ++GSG++G +FA G++VTL+DV E+ + A+ I+ L+ L++ G ++ +
Sbjct: 2 KVFVIGSGVMGSGIGQVFAMAGHEVTLYDVKEEALKKAMEGIRWSLQKLQEKGSVK---D 58
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
+ + + DL+ A +D + + E V E++++K V + + D+ I
Sbjct: 59 VESVLSRIFTSRDLSEA-RDHLVI-EAVFEDIKVKSDVLGRVSPLTDE--IIASNTSSLP 114
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+++ + + H NPP + LVE++ T E ++ I++ +G+ P+ +
Sbjct: 115 ITELSRAVRNPERFLGMHFFNPPVLMKLVEVIRGDNTSEERFREALDIVKSLGKYPLPVR 174
Query: 593 REIDGFVLNRIQYAI 637
+++ GFV+NRI + +
Sbjct: 175 KDVFGFVVNRILFRL 189
>UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus halodurans
Length = 287
Score = 76.6 bits (180), Expect = 5e-13
Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 4/194 (2%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ-LKTLEKDGLLRGNLN 232
VG+VG+G +G A L A G QV L D+ + Q+ DI Q + T + + +G ++
Sbjct: 6 VGVVGAGTMGSGIANLAAMSGLQVVLLDLDDNQL-----DIAWQKINTFMEKSVAKGKMS 60
Query: 233 ADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
E+ +K T + +A V E V ENL++KK+VF LD + ++TI
Sbjct: 61 EAEKEAALGRIKSTTTYE-ELAEADLVIEAVIENLDVKKEVFHTLDTCLANDTIIATNTS 119
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+V+ H NP + LVE+V T + + + ++ +EP+
Sbjct: 120 SMSITEIAAATNRPDRVVGMHFFNPAQLMKLVEVVRGYQTSDDTVETVKQFARQLKKEPI 179
Query: 584 TLSREIDGFVLNRI 625
+ ++ GF++NRI
Sbjct: 180 EVKKDTPGFIVNRI 193
>UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 282
Score = 76.6 bits (180), Expect = 5e-13
Identities = 57/201 (28%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK---TLEKDGLLRG 223
KVG++G+G +G A +FA GY+V L DV + + +A IK L+ K +G
Sbjct: 5 KVGVIGAGTMGNGIAHVFAKSGYKVVLCDVKREFLDRGLATIKKNLEREVAKNKISQEQG 64
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+ AD + ++ DLA D V E E E+K ++F++LD++ + I
Sbjct: 65 QVAADHIYPTLERK-DLA----DCDIVVEAASERFEIKAELFRDLDSICRPDVILATNTS 119
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
K +VI H NP + LVE++ T E + + + E++ + PV
Sbjct: 120 SISITKIAAVTKRPDKVIGMHFFNPVPVMKLVEVIRGLATSDETYQAVKVLSEKLEKTPV 179
Query: 584 TLSREIDGFVLNRIQYAILGE 646
++ + GFV NR+ +L E
Sbjct: 180 EVN-DAPGFVSNRVLMPLLNE 199
>UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=8; Enterobacteriaceae|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Escherichia coli
(strain K12)
Length = 475
Score = 76.6 bits (180), Expect = 5e-13
Identities = 56/202 (27%), Positives = 88/202 (43%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ V ++GSG +G A + AS G+QV L+D+ + +T AI I +L + G L
Sbjct: 6 QTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAET 65
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ + T A+A D + E E LE+KK +F L V T+
Sbjct: 66 CERTLKRLIPVTDIHALAAADLVI--EAASERLEVKKALFAQLAEVCPPQTLLTTNTSSI 123
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+K+ +V H NP + LVE+V T EV ++ + G++PV
Sbjct: 124 SITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVR- 182
Query: 590 SREIDGFVLNRIQYAILGEVWR 655
GF++NR+ E WR
Sbjct: 183 CHSTPGFIVNRVARPYYSEAWR 204
>UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 287
Score = 76.2 bits (179), Expect = 6e-13
Identities = 54/195 (27%), Positives = 87/195 (44%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
+VG+G +G A L A G++V + D+ + A A I+ L+ + G L D
Sbjct: 8 VVGAGNMGAGIAQLCAQQGFEVVIADISLELSDKAKARIEKGLRKRVEQGKLDA-AQKDA 66
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
++ DL A FV E V E++ +K+KVF LDN+ TI
Sbjct: 67 ILSRIQTAGDLGPAAV-CRFVIESVIEDIAIKRKVFAELDNLSPPETILATNTTSLSISA 125
Query: 422 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREI 601
E + +V+ H NPP + LVEI+P T E + ++G++PV E
Sbjct: 126 MAEATRRPERVVQMHFFNPPVIMKLVEIMPGKKTSRETVEAAAEFARQLGKDPVVCKNEA 185
Query: 602 DGFVLNRIQYAILGE 646
+++R+ +L E
Sbjct: 186 PAGIVSRVLGQLLNE 200
>UniRef50_O69856 Cluster: Fatty acid oxidation complex
alpha-subunit; n=6; Actinobacteria (class)|Rep: Fatty
acid oxidation complex alpha-subunit - Streptomyces
coelicolor
Length = 709
Score = 75.4 bits (177), Expect = 1e-12
Identities = 53/200 (26%), Positives = 92/200 (46%), Gaps = 1/200 (0%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
KVG+VG+GL+ A+LF + V L D+ ++++ + + ++ L G + +
Sbjct: 340 KVGVVGAGLMASQLALLFLRRLEVPVVLTDIDQERVDKGVGYVHAEIDKLLGKGRVNQD- 398
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A+ V G D A DA FV E V E + +K+KVF ++ V + I
Sbjct: 399 KANRLKALVTGVLDKAEGFADADFVIEAVFEEMGVKQKVFAEVEAVAPAHAILATNTSSL 458
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+KH +V+ H NP +PL+EIV T + +++ ++ L
Sbjct: 459 SVSEMASKLKHPERVVGFHFFNPVAILPLLEIVRGEQTDEAALATAFGVAKKL-KKTAVL 517
Query: 590 SREIDGFVLNRIQYAILGEV 649
++ FV+NRI +GE+
Sbjct: 518 VKDAPAFVVNRILTRFMGEI 537
>UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 517
Score = 74.9 bits (176), Expect = 1e-12
Identities = 54/204 (26%), Positives = 95/204 (46%), Gaps = 3/204 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
++G+VG+G +G A + A G+ V L+DV + + A+ ++ L+ G +
Sbjct: 3 RLGVVGAGTMGAGIAQVAAQSGFDVLLYDVDPEALARALGRVESDLQRQAARGRI----- 57
Query: 233 ADEQFQCVKGTCDLAIAVKD---AIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
D Q V G ++ D A FV E PE+LELK+++F+ LD + ++ +
Sbjct: 58 PDAQVAEVLGRITTTTSLGDFAAADFVIEAAPEDLELKRRLFERLDRLCREDVVLATNTS 117
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+V+ H NP + LVE+V + + T ++ E +G+ PV
Sbjct: 118 SLSVTQIGALAGRADRVVGMHFFNPVPAMRLVEVVGGDASGEAALQATVSLAEAMGKVPV 177
Query: 584 TLSREIDGFVLNRIQYAILGEVWR 655
+ R+ GF++NR+ GE R
Sbjct: 178 RV-RDTPGFIVNRVARPFTGEALR 200
>UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 74.9 bits (176), Expect = 1e-12
Identities = 51/200 (25%), Positives = 88/200 (44%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
+ K+ +VGSG +G A + A G +V L DV + + + DGL
Sbjct: 19 ARKIAVVGSGYMGGGIAQVLALGGARVALADVSAEVAQSNYDRLLAESDQFVADGLFPAG 78
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
+ + Q + D+ AV DA F++E VPE + +K + + + I
Sbjct: 79 -STEILKQNLWAARDIEEAVADADFIEEAVPEIIAIKHQTLARISAAARPDAIIGSNTST 137
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
E + + + + H NP ++P VEI+P T R ++ G++
Sbjct: 138 ISIADLSEPVTNPERFLGVHFSNPSPFIPGVEIIPHAGTSATTVGAVRDLVHAAGKQTAV 197
Query: 587 LSREIDGFVLNRIQYAILGE 646
+ +++ GFVLNR+QYA+ E
Sbjct: 198 V-KDVTGFVLNRLQYALFHE 216
>UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)]; n=20;
Rickettsia|Rep: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)] - Rickettsia typhi
Length = 720
Score = 74.9 bits (176), Expect = 1e-12
Identities = 47/194 (24%), Positives = 93/194 (47%), Gaps = 2/194 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+KV ++G+G++G A L A+ ++V L D+++K D +K +K L + L +
Sbjct: 6 KKVCVIGAGVMGSGIAALIANSSHRVVLLDILDKDSNDPNKIVKNAVKNLHRQKLPPLSY 65
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
F + +K+ V E + E L++K +++ + + ++TI
Sbjct: 66 PDKVNFITIGNLEHDLDLIKECNLVIEVIVEKLDIKHQLYNKIIPYLKEDTIIASNTSTL 125
Query: 410 XXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
EN+ + K++ I++H NPP Y+ LVE++ K EV +K + +I + +
Sbjct: 126 PLKKLKENLPNNIKSRFIITHFFNPPRYMELVELIIDNTIKDEVIEKISVFLTKILGKTI 185
Query: 584 TLSREIDGFVLNRI 625
+ GF+ NR+
Sbjct: 186 IKCNDTPGFIANRV 199
>UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Psychrobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Psychrobacter cryohalolentis
(strain K5)
Length = 533
Score = 74.1 bits (174), Expect = 3e-12
Identities = 52/194 (26%), Positives = 91/194 (46%), Gaps = 4/194 (2%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ + I+G+G++G A + A VG QV LFD ++ L+ L G
Sbjct: 4 KSLAIIGTGIMGMGIAQIAAQVGIQVLLFDAKAGAAEQGRQSLQAMLEKLAAKGKF---- 59
Query: 230 NADEQFQCVKGTC----DLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 397
DEQ Q D+A + +A V E + ENLE+K+++F+ L+++V TI
Sbjct: 60 -TDEQLQSTLKNLIVIEDIA-KIAEADVVIEAIIENLEIKQQLFKQLESIVPAETILATN 117
Query: 398 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQE 577
N +H +V H NP + +VE++P TK V + ++ + +G
Sbjct: 118 TSSLAVTAIASNCEHPERVAGFHFFNPVPLMKIVEVIPGISTKSSVVETLTSLAKRMGHL 177
Query: 578 PVTLSREIDGFVLN 619
V ++++ GF++N
Sbjct: 178 GV-VAKDTPGFIVN 190
>UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Caulobacter sp. K31|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Caulobacter sp. K31
Length = 296
Score = 74.1 bits (174), Expect = 3e-12
Identities = 59/210 (28%), Positives = 101/210 (48%), Gaps = 3/210 (1%)
Frame = +2
Query: 35 SKFKSE-KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG 211
S F E K+G+VG+GL+G A++FA G V L D + A+A + L G
Sbjct: 10 SPFAPELKIGVVGAGLMGAEIALVFALGGMDVLLHDRDAAALEKALARLSALLDRGVSRG 69
Query: 212 LLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 391
L A + ++ DL+ D V E V E+LE+K +V LD + +
Sbjct: 70 LYTEGRRATA-LENIRLAPDLS-RFGDRDLVTEAVFESLEVKGQVLAALDEACPEACVIA 127
Query: 392 XXXXXXXXXXXXENM--KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEE 565
+ + + + + +H +P + LVE+VPA T PE T ++++
Sbjct: 128 SNTSTLPISTLGAALSPERRPRFLGAHYFSPVSRMLLVEVVPAFETSPETVAWTTSLLKR 187
Query: 566 IGQEPVTLSREIDGFVLNRIQYAILGEVWR 655
IG++P+ + +++ GF +NR+ +A+L E R
Sbjct: 188 IGKQPIAV-KDVPGFAVNRMLHAMLIEAVR 216
>UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 387
Score = 73.7 bits (173), Expect = 3e-12
Identities = 48/192 (25%), Positives = 86/192 (44%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+K+ ++GSG +G A + GY V + DV ++ + + + +K + L G L
Sbjct: 7 KKIAVIGSGAMGHGIAQVCIMAGYTVVMVDVKQEFLDNGMKKVKESMDFLVGKGKLSAE- 65
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ D + + D AV D V E VPE ++LKKKVF ++ + +
Sbjct: 66 DKDRMMGQLSTSLDNKAAVADVQVVIEAVPEIMDLKKKVFADVSSAAPAEALLASNTSTM 125
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ + + H NP + LVE++ T E + ++IG+ PV +
Sbjct: 126 SITEIATAVTKPERFLGMHFFNPVNRMKLVEVIFGEKTSAENVDLLCELSKKIGKIPVKV 185
Query: 590 SREIDGFVLNRI 625
++ GF++NRI
Sbjct: 186 LKDSPGFIVNRI 197
>UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5;
Trichocomaceae|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 338
Score = 73.3 bits (172), Expect = 5e-12
Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 2/127 (1%)
Frame = +2
Query: 272 LAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQ 451
L A A VQE PEN++ K+ + ++ V + M+ K +
Sbjct: 93 LESACASATIVQEQGPENVDWKQSAWARIEAVAPPSAHLWTSTSGIAASIQQAKMQDKTR 152
Query: 452 VIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIG--QEPVTLSREIDGFVLNRI 625
++V HP NPP +PL+EIVPAP T E + R G PV + +EI GFV NR+
Sbjct: 153 LLVVHPFNPPNIMPLLEIVPAPGTSAERVEFAREYFSLPGSRHRPVVIQKEIPGFVGNRL 212
Query: 626 QYAILGE 646
+A+L E
Sbjct: 213 AFALLRE 219
>UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Halobacterium salinarium (Halobacterium halobium)
Length = 286
Score = 73.3 bits (172), Expect = 5e-12
Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 1/200 (0%)
Frame = +2
Query: 29 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEK 205
M S +E +G+VG+G +G A + A+ GY V + D+ ++ + I+ L + +
Sbjct: 1 MRSLADTETIGVVGAGTMGAGIAQVAATAGYTVVMRDIEQEYVDAGFDSIESSLDRFVSN 60
Query: 206 DGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 385
D L +AD + GT DLA + D V E E++E+K+ +F++LD+ + ++ +
Sbjct: 61 DDL--SEADADAIVDRITGTTDLA-ELADCDVVIEAAVEDMEIKQDIFRDLDDALPEDVV 117
Query: 386 XXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEE 565
++V+ H +NP + VE+V T +V A+ E+
Sbjct: 118 LATNTSTLSITTIASVTDRASRVVGLHFMNPVPIMTGVEVVVGEKTDADVVAFAHALAED 177
Query: 566 IGQEPVTLSREIDGFVLNRI 625
+ +E S + GFV NRI
Sbjct: 178 LDKE-TWESDDKPGFVTNRI 196
>UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 377
Score = 72.9 bits (171), Expect = 6e-12
Identities = 49/196 (25%), Positives = 95/196 (48%), Gaps = 3/196 (1%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
+E+V +VG+G +G A A+ G++V L DV E+ + + ++ L+ + RG
Sbjct: 2 AERVAVVGAGTMGSGIAQSAAACGFEVALVDVSEEALERGMRSVRANLERRVE----RGR 57
Query: 227 LNADEQFQCVKGTCDLAIAVKD---AIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 397
++++E+ V G +++ A V E V E++ +K++VF+ L+ VV + +
Sbjct: 58 ISSEER-DGVLGRISTFTSLESCAGASLVIEAVVEDIGVKREVFRTLERVVGEEAVLATN 116
Query: 398 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQE 577
+ +V+ H NP + LVE+V P + E + +G+
Sbjct: 117 TSSLSVAEISATTRRPERVVGMHFFNPAPVMRLVEVVRGPRSGEEALARAEEAARRMGKT 176
Query: 578 PVTLSREIDGFVLNRI 625
PV +S + GF++NR+
Sbjct: 177 PVRVS-DTPGFIVNRV 191
>UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=12; Actinomycetales|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 723
Score = 72.9 bits (171), Expect = 6e-12
Identities = 56/201 (27%), Positives = 95/201 (47%), Gaps = 2/201 (0%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFA-SVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 226
KVG+VG+GL+ A+LFA + V + D+ + ++ + + ++ K L K +
Sbjct: 350 KVGVVGAGLMASQLALLFARQLKVPVVMTDIDQARVDKGVGYVHAEVDKMLAKKRISADA 409
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
N + V G+ A DA FV E V E L +KK+VF ++ +V I
Sbjct: 410 ANRTKAL--VTGSVSKD-AFADADFVIEAVFEELNVKKQVFAEVEAIVSPECILATNTSS 466
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
++ H +++ H NP +PL+EIV AP T V + + + ++
Sbjct: 467 LSVTAMAADLAHPERLVGFHFFNPVAVMPLLEIVRAPKTDDAVLATAFELAKGL-KKTAV 525
Query: 587 LSREIDGFVLNRIQYAILGEV 649
L ++ FV+NRI ++GEV
Sbjct: 526 LVKDAAAFVVNRILLRLMGEV 546
>UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein; n=19; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein - Croceibacter
atlanticus HTCC2559
Length = 802
Score = 72.5 bits (170), Expect = 8e-12
Identities = 56/213 (26%), Positives = 98/213 (46%), Gaps = 16/213 (7%)
Frame = +2
Query: 35 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDA------IADIKVQLKT 196
+K + K+ ++GSG++G A FA++G +V L D+V +++ + + KV
Sbjct: 2 AKRRINKIAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELNEKEKAKGLTLEDKVVRNR 61
Query: 197 LEKDGL---LRGN----LNADEQFQCVKGTCDLAIA-VKDAIFVQECVPENLELKKKVFQ 352
+ D L ++ + D + G + IA VKD ++ E V E L++KK+VF+
Sbjct: 62 IVNDALQSSIKSKPAPLYHKDFASRISTGNLEDDIAKVKDVDWIIEVVVERLDIKKQVFE 121
Query: 353 NLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQ--VIVSHPVNPPYYVPLVEIVPAPWTK 526
NL+ + T+ E Q +H NPP Y+ L EI+P P T
Sbjct: 122 NLEKHRTEGTLITSNTSGIPINLMSEGRSEDFQKHFCGTHFFNPPRYLELFEIIPGPKTS 181
Query: 527 PEVTKKTRAIMEEIGQEPVTLSREIDGFVLNRI 625
PEV E+ + ++++ F+ NR+
Sbjct: 182 PEVLDFLNGYGEKFLGKTSIVAKDTPAFIGNRV 214
>UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=16;
Bacteroidetes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 298
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/195 (27%), Positives = 82/195 (42%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
I+GSG +G A FA G+QV L D + A+ I L+ G++ + +
Sbjct: 10 IIGSGTMGSGIAHSFAQFGFQVFLCDSNAAALNKAMLQISTNLERQISKGIIPDS-EKET 68
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
+ D A K V E VPE LE+K +F+ LD TI
Sbjct: 69 IISRITPITDFKEAAKTVSLVVEAVPELLEIKADLFKELDMHCPPETILASNTSSISITT 128
Query: 422 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREI 601
+VI H +NP + LVEI+ T E T++ I ++ + PV + +
Sbjct: 129 LASYTSRPEKVIGMHFMNPVPVMQLVEIINGLLTSSETTRRIEEISTQLNKIPVQ-TADY 187
Query: 602 DGFVLNRIQYAILGE 646
GF+ NRI ++ E
Sbjct: 188 PGFISNRILMPMINE 202
>UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 748
Score = 72.1 bits (169), Expect = 1e-11
Identities = 50/188 (26%), Positives = 84/188 (44%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
I+G+G +G AM FA G V + D ++ + + ++ T K G + D+
Sbjct: 349 IIGAGTMGGGIAMCFAGAGIPVVIVDTTQEALDRGMERVRANYATSVKRGSISQE-QVDK 407
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
+ + D A AV DA V E V E++ +KK++F +L+ V T+
Sbjct: 408 RLALITPATDRA-AVADADLVIEAVFEDMAVKKEIFSDLEKRVKPGTVLASNTSALDVDE 466
Query: 422 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREI 601
+ + H +P + L+E+V A + PE A+ +IG+ PV S
Sbjct: 467 IAAALDRPEDFVGMHFFSPANVMKLLEVVQAAKSSPEAILTAMAVGRKIGKVPV-WSGNC 525
Query: 602 DGFVLNRI 625
DGF+ NR+
Sbjct: 526 DGFIGNRM 533
>UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9;
Gammaproteobacteria|Rep: 3-hydroxyacyl CoA dehydrogenase
- Legionella pneumophila (strain Corby)
Length = 284
Score = 72.1 bits (169), Expect = 1e-11
Identities = 51/201 (25%), Positives = 88/201 (43%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 223
K K+ ++G+G +G LFA G+ VTL D ++ Q+ A I L L L
Sbjct: 2 KQTKLTLLGAGTMGSGITQLFAQYGFYVTLIDNLQSQLDKAKDTIAKNLHYLALTQNLES 61
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+ + + T L +K + ++ E + EN E KK ++Q L I
Sbjct: 62 THSIETILASITFTTKLD-ELKQSEYIIENITENWERKKALYQVLKKECSATCILGVNTS 120
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ H +VI H +NP +P+VE++ T +KTR ++E++ ++ +
Sbjct: 121 SIPITKIASLVDHPQRVIGVHFMNPAPMMPMVEVIKGYHTDELTIEKTRTLLEQVHKKMI 180
Query: 584 TLSREIDGFVLNRIQYAILGE 646
+ + GFV NR + E
Sbjct: 181 VVKDSV-GFVSNRAMMIFINE 200
>UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=11; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Deinococcus radiodurans
Length = 347
Score = 71.7 bits (168), Expect = 1e-11
Identities = 51/203 (25%), Positives = 84/203 (41%)
Frame = +2
Query: 35 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGL 214
S + V + GSG++G A A G+ V L+D+ + I A + ++D
Sbjct: 50 SSMSIKTVTVCGSGVLGSQIAFQTAFHGFDVHLYDINDAAIAKARETLGKLQARYQQDLK 109
Query: 215 LRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 394
+ D F + D+A AVK V E +PEN+++K+K + L V D NTI
Sbjct: 110 VDAQQTGDA-FARISFFTDIAEAVKGVDLVIEAIPENMDIKRKFYNQLGEVADPNTIFAT 168
Query: 395 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQ 574
E + + H N + EI+ P T V ++IG
Sbjct: 169 NSSTLLPSQFMEETGRPEKFLALHFANEIWKFNTAEIMRTPRTDDAVFDTVVQFAKDIGM 228
Query: 575 EPVTLSREIDGFVLNRIQYAILG 643
+ + +E G++LN + +LG
Sbjct: 229 VALPMYKEQAGYILNTLLVPLLG 251
>UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 286
Score = 71.7 bits (168), Expect = 1e-11
Identities = 51/197 (25%), Positives = 90/197 (45%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VG+VG+G +G A A G+ V + D + + A + ++ L+ G G A
Sbjct: 9 VGVVGAGTMGAGVAECLAQAGHDVIVVDPDPQAVDQARSRMRDSLRLAILLGRAGGPKPA 68
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
+ + V T ++ ++DA V ECVPE ++LK+KVF LD V + +
Sbjct: 69 EVTAR-VHWTGEMT-DLRDAAVVIECVPERIDLKEKVFAELDRVCAPDALLASCTSGIPV 126
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+ +V+ H +NP VE+V P T P+ + A++ + + + +
Sbjct: 127 DRLADTTTRPERVVGLHFMNPAPLKDTVEVVRGPRTSPQSLDRALALLASLNKTGIVVG- 185
Query: 596 EIDGFVLNRIQYAILGE 646
+ GF+LNR+ + E
Sbjct: 186 DGPGFLLNRVLMLCIAE 202
>UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 309
Score = 71.7 bits (168), Expect = 1e-11
Identities = 49/195 (25%), Positives = 85/195 (43%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
++G+G++G A+ A G Q TL +A+ + + L + L L+ D
Sbjct: 8 VIGTGMMGPGIALTLALGGVQTTLLSRTPAGAERGVAEARRLGRVLVEQELAAA-LDLD- 65
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
+ G+ D ++ A V E PE + K+++F +D V + +
Sbjct: 66 ----IAGSTDFEYSIGQADIVIESGPEEMGWKQELFARMDRVARADAVLASNTSGLSVTA 121
Query: 422 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREI 601
QV+ +H NPP+ VPLVEI+ T P R ++ G+ PV + +
Sbjct: 122 IAAECARPEQVLATHFWNPPHLVPLVEIIQGRATSPAAAAAVRELLTACGKTPVVVKLDR 181
Query: 602 DGFVLNRIQYAILGE 646
G + NR+Q A++ E
Sbjct: 182 PGQLGNRLQMALVRE 196
>UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
root|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Thermobifida fusca (strain YX)
Length = 398
Score = 71.3 bits (167), Expect = 2e-11
Identities = 54/194 (27%), Positives = 88/194 (45%), Gaps = 3/194 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KVG+VG G +G +FA G+ VT ++ + + ++ K+L K + +G L
Sbjct: 7 KVGVVGLGTMGAGIVEVFARAGFTVTGVEIDDAALERGRTHLE---KSLAK-AVAKGKLT 62
Query: 233 ADEQFQCVKGTCDLAIA---VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
DEQ + + G + + DA E VPE L++K+ VF +LD ++ I
Sbjct: 63 EDEQ-RAILGRVTFTTSRDDLADAHLAVEAVPERLDIKRSVFADLDRILPPAAILATNTS 121
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+VI H NP + LVEIV T+P V + ++ +G+ PV
Sbjct: 122 SLSVTEIAALTSRPGKVIGLHFFNPAPVMRLVEIVTTVVTEPHVRETATQVVTRLGKTPV 181
Query: 584 TLSREIDGFVLNRI 625
+ + GFV N +
Sbjct: 182 AVG-DRAGFVANAL 194
>UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Pseudomonas fluorescens PfO-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Pseudomonas fluorescens (strain PfO-1)
Length = 703
Score = 70.9 bits (166), Expect = 2e-11
Identities = 55/194 (28%), Positives = 86/194 (44%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 223
K KV ++G+G +G AM FA VG V L D+ + + + ++ + K G L
Sbjct: 297 KINKVAVIGAGTLGGGIAMSFADVGIPVALMDLDGRTLDRGLKRVRENYQLSVKRGKLSA 356
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+ ++ + + GT D A + DA + E V E +E K +VF L++V I
Sbjct: 357 -VQMQQRMELLFGTLDYA-DLSDADLIIEAVCEKMESKHQVFLALESVCKPGAILATNTS 414
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ + VI H +P + LVEIV T P+V I IG+ PV
Sbjct: 415 SLDIDALAKMVSRPQDVIGMHFFSPANVMRLVEIVLCQTTAPDVVTAVMDIARRIGKLPV 474
Query: 584 TLSREIDGFVLNRI 625
+S G + NR+
Sbjct: 475 -ISGNSAGSIGNRM 487
>UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 295
Score = 70.9 bits (166), Expect = 2e-11
Identities = 54/203 (26%), Positives = 92/203 (45%), Gaps = 3/203 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN- 232
V I+G+G +G A + A G+ V+L D+ + D + I+ L+ +G+ R +
Sbjct: 4 VAILGAGTMGHGIAQVSAMAGHDVSLRDIEADIVDDGLTAIESNLE----EGIAREKVTE 59
Query: 233 --ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
A+ +KGT L AV A V E VPE + +K + +++ VD T+
Sbjct: 60 STAEATIDRLKGTTSLEEAVTGADLVVEAVPEEMAIKHETLTAVESHVDPATLIASNTSS 119
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+ + + I H NP + + LVEIV A T E + R + I + PV
Sbjct: 120 LSLTEIASVLDYPERAIGLHFFNPVHIMALVEIVVAEQTSAETIARAREFVNGIDKTPVE 179
Query: 587 LSREIDGFVLNRIQYAILGEVWR 655
++ + GF +R+ ++ E R
Sbjct: 180 VA-DAPGFASSRLGVSLGVEAMR 201
>UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Archaeoglobus fulgidus
Length = 295
Score = 70.9 bits (166), Expect = 2e-11
Identities = 49/178 (27%), Positives = 84/178 (47%), Gaps = 2/178 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+G+VG+G++G A + A GY V + DV E+ + A+ I+ L + + +G ++
Sbjct: 9 IGVVGAGVMGHGIAQVAARTGYDVVMVDVSEEVLKKAMELIESGPFGLRRL-VEKGKMSE 67
Query: 236 DEQFQCVKG--TCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
DE + T A+KDA F+ E V E +LKKK+F LD + TI
Sbjct: 68 DEAKAVMARIRTSTSLEALKDADFIIEAVTEKADLKKKIFAELDRICKPETIIASNTSAI 127
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
++ K + I H NP + L+E++ T E T + +++G+ P+
Sbjct: 128 MISDLATAVERKDKFIGMHWFNPAPVMRLIEVIRGALTSDETFNITVELSKKMGKIPI 185
>UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subunit
precursor; n=1; Euglena gracilis|Rep:
L-3-hydroxyacyl-CoA dehydrogenase subunit precursor -
Euglena gracilis
Length = 320
Score = 70.5 bits (165), Expect = 3e-11
Identities = 55/204 (26%), Positives = 88/204 (43%), Gaps = 7/204 (3%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLE----KDG---L 214
VG+VG G +G A + A+ GY+V D+ ++ I ++ L + KDG
Sbjct: 25 VGVVGMGAMGHGIAQMTAAAGYKVVAVDIDANMLSKGIKAVEDSLSKVAAKAVKDGKADK 84
Query: 215 LRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 394
NA + + + D+ A+ V E + E+L +KKK F +L V N I
Sbjct: 85 ATAEKNAADVRSRITTSGDIG-ALSSCDLVIESIIEDLNIKKKFFADLGKVAGANAILAS 143
Query: 395 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQ 574
E + + H NP + LVE++ TK +V K A + IG+
Sbjct: 144 NTSSFPITQLGEASGRTSNFLGLHFFNPVQMMKLVEVIKTKDTKEDVYKLGFAFSKSIGK 203
Query: 575 EPVTLSREIDGFVLNRIQYAILGE 646
EPV + GF++NR+ L +
Sbjct: 204 EPVACG-DTPGFIVNRLLVPFLAQ 226
>UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenase;
n=2; Streptomyces|Rep: Putative 3-Hydroxyacyl-CoA
dehydrogenase - Streptomyces coelicolor
Length = 504
Score = 70.1 bits (164), Expect = 4e-11
Identities = 52/194 (26%), Positives = 89/194 (45%), Gaps = 1/194 (0%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRG 223
S V +VG+G +G+ A + G+ V L+D V+ + +A I +L + +EKD L
Sbjct: 7 SSPVAVVGTGTMGQGIAQVALVAGHPVRLYDAVDGRAREAADAIGARLDRLVEKDRLTGA 66
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+A GT + D V E V E L++K+++F+ L++VV D+ +
Sbjct: 67 ERDAARARLVPAGTLG---ELADCALVVEAVVERLDVKQELFRALEDVVGDDCLLATNTS 123
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
++ + + H NP +PLVE+V T P + G+ PV
Sbjct: 124 SLSVTAVGGALRVPGRFVGLHFFNPAPLLPLVEVVSGFATDPASATRAYETARAWGKTPV 183
Query: 584 TLSREIDGFVLNRI 625
+ + GFV+NR+
Sbjct: 184 ACA-DTPGFVVNRV 196
>UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Psychromonas ingrahamii 37|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Psychromonas ingrahamii (strain 37)
Length = 511
Score = 70.1 bits (164), Expect = 4e-11
Identities = 49/196 (25%), Positives = 91/196 (46%)
Frame = +2
Query: 38 KFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLL 217
K + V ++G+G +G A + A GYQV LFD+ + + +A +I+ QL+ K G +
Sbjct: 3 KLLFKTVAVIGAGAMGAGIAQVAAQSGYQVYLFDLAKGKAEEAKENIEKQLERRVKKGRM 62
Query: 218 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 397
+ + + +L+ + A V E + ENLE+K+ +F+ L+ + + I
Sbjct: 63 E-QQTLESTLLRIHCSSELS-EIASANLVIEAIVENLEIKQGLFKELETICSADCILASN 120
Query: 398 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQE 577
+K + I H NP + LVE++ T + + + G++
Sbjct: 121 TSSISITAIASALKSPERFIGLHFFNPAPVMKLVEVIQGVATADNIAETAQQWARSCGKK 180
Query: 578 PVTLSREIDGFVLNRI 625
V L+ I GF++NR+
Sbjct: 181 SV-LACSIPGFIVNRV 195
>UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 589
Score = 70.1 bits (164), Expect = 4e-11
Identities = 54/205 (26%), Positives = 90/205 (43%), Gaps = 3/205 (1%)
Frame = +2
Query: 41 FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT-LEKDGLL 217
++ V I+G+G++GR A ++AS GY V + D +Q D +A +K + E G
Sbjct: 11 YRERPVAILGAGVLGRRIACIWASAGYDVQVRDPSPEQRADCVAYVKQHVVAYAEHTGAA 70
Query: 218 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 397
G + E DL V +A V E VPE ++LK F+ LD + + I
Sbjct: 71 PGEVTTSE---------DLKNTVNNAWLVIEAVPEKIQLKIDTFEQLDKLAPTDCILASN 121
Query: 398 XXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIG 571
+ + K +++ H PP V +VE++ +T P + + +E
Sbjct: 122 SSSYKSSEMLDKVSDSAKPRILNMHYYMPP-QVMVVELMTNGFTDPSIIQFLVERSKEAA 180
Query: 572 QEPVTLSREIDGFVLNRIQYAILGE 646
P +E GF+ NR+ A+ E
Sbjct: 181 TIPYVARKESTGFIFNRLWAAVKRE 205
>UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase,
mitochondrial precursor; n=40; Eukaryota|Rep:
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 314
Score = 70.1 bits (164), Expect = 4e-11
Identities = 51/212 (24%), Positives = 89/212 (41%), Gaps = 4/212 (1%)
Frame = +2
Query: 32 ASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG 211
A K + V ++G GL+G A + A+ G+ V L D E + + I+ L+ + K
Sbjct: 22 AKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKK 81
Query: 212 LLRGNLNADE----QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDN 379
DE + + D A V V E + ENL++K ++F+ LD ++
Sbjct: 82 FAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEH 141
Query: 380 TIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIM 559
TI + + H NP + LVE++ P T + +
Sbjct: 142 TIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFS 201
Query: 560 EEIGQEPVTLSREIDGFVLNRIQYAILGEVWR 655
+ +G+ PV+ ++ GF++NR+ L E R
Sbjct: 202 KALGKHPVS-CKDTPGFIVNRLLVPYLMEAIR 232
>UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase;
n=7; Bacteria|Rep: Beta-hydroxybutyryl-CoA dehydrogenase
- Polyangium cellulosum (Sorangium cellulosum)
Length = 293
Score = 69.3 bits (162), Expect = 7e-11
Identities = 54/200 (27%), Positives = 86/200 (43%), Gaps = 3/200 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VG+VG+G++G A A G+ V L DV E + A I+ L+ + G A
Sbjct: 12 VGVVGAGVMGVGVAQSLAQTGHDVVLVDVSEAALARARMGIRNGLRAVTLFGSAEDKKRA 71
Query: 236 DEQ---FQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
+ + V T D + A FV E V E ++K++V+ L+ V I
Sbjct: 72 GDPKAVLERVAFTTDYG-RLAGADFVVENVTEKWDIKREVYARLEGVCRPEIIFAADTSA 130
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
K +QV+ H +NP P+VE++ T PE + + E+G+ V
Sbjct: 131 ISITRIGSVTKRPSQVVGMHFMNPVPLKPMVEVIRGFHTSPETLGAAKRFLAEMGKTCVV 190
Query: 587 LSREIDGFVLNRIQYAILGE 646
+ + GFV NR+ + E
Sbjct: 191 V-EDAPGFVSNRVLMLTINE 209
>UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=54;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 284
Score = 68.9 bits (161), Expect = 1e-10
Identities = 54/203 (26%), Positives = 86/203 (42%), Gaps = 2/203 (0%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 226
E VG+VG+G +G A A G V + DV + + IA +K L + + KD L
Sbjct: 4 EIVGVVGAGTMGNGIAQTAAVAGLNVVMIDVSDAALEKGIATLKGSLDRLVSKDKL--DA 61
Query: 227 LNADEQFQCVKGTCDLA-IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
D + + D A +A D + E EN+ELK ++ + ++ V I
Sbjct: 62 ATRDAALARITTSTDYAKLAAADIVI--EAATENVELKGRILKQIEAVARAEAIIATNTS 119
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ A+ + H NP +PLVEI+ T R + E + P+
Sbjct: 120 SISITALAAPLADPARFVGMHFFNPVPLMPLVEIIRGLQTSDATASAVRELTERFDKSPI 179
Query: 584 TLSREIDGFVLNRIQYAILGEVW 652
+ R GFV+NRI ++ E +
Sbjct: 180 GV-RNSPGFVVNRILVPMINEAF 201
>UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Lactobacillus reuteri|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Lactobacillus reuteri F275
Length = 294
Score = 68.9 bits (161), Expect = 1e-10
Identities = 52/201 (25%), Positives = 93/201 (46%), Gaps = 4/201 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLF----DVVEKQITDAIADIKVQLKTLEKDGLL 217
+ + I G+G++G A A G+ V+++ D E++I +D + L +K+
Sbjct: 2 KNIMIAGAGVLGSQIAYQTALSGFNVSVYNHHIDTAERRIKALKSDYERDLHLTDKE--F 59
Query: 218 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 397
+ LN + T D+A AVKDA + E +PE+LELK++ ++ + + + TI
Sbjct: 60 QQGLNNIKVI-----TDDVATAVKDADLMIEALPESLELKEQFYEEVSELAPEKTIFASN 114
Query: 398 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQE 577
+ + H N + +VEI+ T PEV ++ EI
Sbjct: 115 SSTFIPSQLAPYTDRPEKFLNMHFANQIWKFNVVEIMGTSQTSPEVIEEATKFAREIKMV 174
Query: 578 PVTLSREIDGFVLNRIQYAIL 640
PV L++E G++LN + +L
Sbjct: 175 PVILNKEQHGYILNSLLIPLL 195
>UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 313
Score = 68.9 bits (161), Expect = 1e-10
Identities = 36/121 (29%), Positives = 58/121 (47%)
Frame = +2
Query: 290 DAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHP 469
D V ECVPE L++K+++F L+ + +K A++I H
Sbjct: 79 DVDLVIECVPERLDIKQELFAKLEKYAKPEAVLASNSTSFPISEIASGLKTAARMIGLHF 138
Query: 470 VNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREIDGFVLNRIQYAILGEV 649
P + VP VE+V T P V +M G PVT+ +++ GF+ NR+Q+A+ E
Sbjct: 139 FMPAHLVPCVEVVYGEKTSPMVGDSLSRLMTACGMVPVTVKKDLPGFLANRLQHALSREA 198
Query: 650 W 652
+
Sbjct: 199 F 199
>UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 275
Score = 68.5 bits (160), Expect = 1e-10
Identities = 56/203 (27%), Positives = 92/203 (45%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
S + +VG G +GR A+ + G++VTL DV E + A A + + RG
Sbjct: 2 STSMVVVGGGTMGRGIAIAALATGFEVTLVDVAEDVLDRAQARVSEHFARHPQPD--RGV 59
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
L+ T LA +++ A V E VPE L LK ++FQ L T+
Sbjct: 60 LHT---------TTSLAGSLETAEVVIEAVPEILPLKTQIFQQLRG-APPGTLLVSNTST 109
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
E ++V+ H NP + +PLVE+V T + + A+ +G++P+
Sbjct: 110 MSISALAEACGGSSRVVGMHFFNPAHRMPLVEVVVGTRTSDDARDRAVALAVRLGKDPIV 169
Query: 587 LSREIDGFVLNRIQYAILGEVWR 655
+ R++ GFV +R+ + E R
Sbjct: 170 V-RDLPGFVTSRLGLILGTEAMR 191
>UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr11 scaffold_13, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 724
Score = 68.5 bits (160), Expect = 1e-10
Identities = 48/191 (25%), Positives = 85/191 (44%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+KV ++G GL+G A + V L +V + + I I+ ++ L G L +
Sbjct: 309 KKVAVIGGGLMGSGIATALITSNIYVVLKEVNSEYLLKGIKTIEANVRGLVTKGKLTQD- 367
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A + +KG D + KD V E V EN+ LK+K+F ++ + + I
Sbjct: 368 KARKALSMLKGVLDYS-EFKDIDMVIEAVIENISLKQKIFSEIEKICSPHCILATNTSTI 426
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
E + ++I +H +P + +PL+E+V T +V + + I + PV +
Sbjct: 427 DLNLVGEKTSSQDRIIGAHFFSPAHVMPLLEVVRTEKTSAQVILDLMTVGKAIKKIPVVV 486
Query: 590 SREIDGFVLNR 622
GF +NR
Sbjct: 487 G-SCTGFAVNR 496
>UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 312
Score = 68.1 bits (159), Expect = 2e-10
Identities = 50/191 (26%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ-LKTLEKDGLLRGNLN 232
+ ++G+G +G + A+LFA+ G++VTL D + A + + L+ LE+ GL +
Sbjct: 5 IAVIGAGTMGAAIALLFANAGFEVTLVDKSRGALRRAEDRHRGESLEELEEAGLRK---- 60
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
D + T +L + D F+ E + E L K ++F+ ++ ++ +
Sbjct: 61 QDNPASLITYTTELRVYECD--FIVEAIVERLRDKIELFRKIEE-INSPAVLATNTSSFM 117
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
++ + ++ + H NPP +PLVE V E ++ + + IG+EPV L
Sbjct: 118 PSEIARHLANPERLTLFHFSNPPILMPLVE-VGGEIVSDETVERAVEMAKSIGKEPVVLR 176
Query: 593 REIDGFVLNRI 625
+E G VLNR+
Sbjct: 177 KECRGHVLNRM 187
>UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 289
Score = 67.7 bits (158), Expect = 2e-10
Identities = 52/192 (27%), Positives = 85/192 (44%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
++V I G+G +GRS + A G +V L+DV E + A + V++ + G L
Sbjct: 7 KRVLIAGAGTMGRSIGLSCAVRGCEVILYDVKEDALEAARRAMAVKIDKMVPAGALTPEA 66
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A+ + T DLA A DA V E VPE+ ++K + F+ L V + TI
Sbjct: 67 -AESIKANITTTTDLAAAGADADLVSESVPEDPDIKGEFFEKLHGVCPERTIFTTNTSSL 125
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ + H +P + LV+++ T E + R E IG P+ L
Sbjct: 126 VPSMFAARTGRPDRFLAFH-FHPGF--KLVDVMGHAGTSAETVETVRRFAERIGHSPIVL 182
Query: 590 SREIDGFVLNRI 625
+E G++ N +
Sbjct: 183 KQEKAGYLFNSL 194
>UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB3;
n=1; Mycobacterium ulcerans Agy99|Rep:
3-hydroxybutyryl-CoA dehydrogenase FadB3 - Mycobacterium
ulcerans (strain Agy99)
Length = 294
Score = 67.7 bits (158), Expect = 2e-10
Identities = 54/201 (26%), Positives = 89/201 (44%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 223
+S V ++G+G +GR A++FAS G V ++ +Q A + L L +D RG
Sbjct: 13 RSRPVAVIGAGTLGRRIALMFASRGGTVRIYARRAEQRAQATQYVADNLPKLLQD---RG 69
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+ V T LA A++ A E VPE LE+K ++ +D +TI
Sbjct: 70 F----GEVGSVTATDCLATALEGAWLAVESVPEKLEIKTALWGQIDQAAPPDTIFATNSS 125
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+N++ K ++ +H PP + L +++ T + ++ E G P
Sbjct: 126 SFPSRLMADNVRDKTRLCNTHFYMPPQFNAL-DLMSDGETDRGLLDTLLTVLPEFGVHPF 184
Query: 584 TLSREIDGFVLNRIQYAILGE 646
RE GF+ NR+ AI E
Sbjct: 185 EARRECTGFIFNRVWAAIKRE 205
>UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein 1;
n=2; Caenorhabditis|Rep: Hydroxy-acyl-coa dehydrogenase
protein 1 - Caenorhabditis elegans
Length = 299
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/197 (26%), Positives = 88/197 (44%), Gaps = 7/197 (3%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK---VQLKTLEKDGLLRGN 226
V I G+G++G A + GY V L+ EK++ +A IK +++ + +K +
Sbjct: 13 VAIFGAGMMGSGIAQVCLQAGYPVNLYGRSEKKLLEARETIKKNLIRVASKKKTDVPMEP 72
Query: 227 LNADE----QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 394
+E Q ++ D+ A +DA E V ENL+LK +FQ + N +
Sbjct: 73 AALEEIAQIQLDLLQIHTDIPSAAEDAAMAIEAVAENLDLKLDIFQTIQKTCPQNCMLIT 132
Query: 395 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQ 574
+++ A H NP + LVE+V T PE T +EI +
Sbjct: 133 NTSSLKLSQMLPVIQNPALFAGLHFFNPVPVMKLVEVVSTDETSPETTNFLFNFCKEIKK 192
Query: 575 EPVTLSREIDGFVLNRI 625
PV +++ GF++NR+
Sbjct: 193 LPVA-AKDTPGFIVNRL 208
>UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 344
Score = 67.3 bits (157), Expect = 3e-10
Identities = 55/202 (27%), Positives = 89/202 (44%), Gaps = 10/202 (4%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVG-YQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
+ + + G+GL+G A + A G + VTL DV +K + + I L + K + +
Sbjct: 42 QNITVFGAGLMGAGIAQVLAHKGKFNVTLSDVTDKALANGQTIISKSLGRIVKKSMAEAS 101
Query: 227 LNADEQFQCVKG-------TCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 385
A+EQ Q VKG T D AVKD V E + EN+ +KK +F LD + +
Sbjct: 102 --AEEQAQYVKGIVDSIKVTTDPEAAVKDTDLVIEAIIENVGIKKDLFGFLDGKAPKDAL 159
Query: 386 XXXXXXXXXXXXXXENMKHKAQVIVS--HPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIM 559
E + + Q + H NP + LVE+V T + +
Sbjct: 160 FASNTSSLSITDVAEAVSAQRQELFGGFHAFNPVPQMKLVEVVRTTKTSNDTFDSLTEVA 219
Query: 560 EEIGQEPVTLSREIDGFVLNRI 625
+ +G+ PV + GF++NR+
Sbjct: 220 KRMGKTPVACI-DSPGFIVNRL 240
>UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep:
3-hydroxybutyryl-coA dehydrogenase - Blastopirellula
marina DSM 3645
Length = 319
Score = 66.5 bits (155), Expect = 5e-10
Identities = 46/201 (22%), Positives = 90/201 (44%), Gaps = 2/201 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL-- 229
VG+VG GL+GR + +QV +D+ + A A + L+ L + + +
Sbjct: 6 VGVVGLGLMGRGICTSLLANNFQVVAYDINPESFAAARAHVASALEELARHPSVAEAIPE 65
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
N FQ T DL+ + D FV E +PE+ +K++ L+ ++ ++T
Sbjct: 66 NWPSHFQL---TADLS-PLGDCDFVIESIPEDPVIKQETIAALERLLPNSTPIASNTSAL 121
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ + ++I H P + +EI+ T + ++G++P +
Sbjct: 122 PISLLQAHCQLPQRIIGMHWAEPCHLTRFLEIIRGEHTDDATADSAANLGRQLGKDPTIV 181
Query: 590 SREIDGFVLNRIQYAILGEVW 652
R++ GF++NR+ YA+ E +
Sbjct: 182 QRDVPGFIVNRLAYAMYREAF 202
>UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 722
Score = 66.5 bits (155), Expect = 5e-10
Identities = 48/192 (25%), Positives = 87/192 (45%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ VG+VG GL+G A G QV L ++ ++ + + I+ L ++ + G + +
Sbjct: 305 KSVGVVGGGLMGSGIATACLLAGIQVVLKEIKQEFLDAGVGRIQSNLTSMVRKGRMTED- 363
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A + VK T + V E V ENL LK+K+F L+ + + I
Sbjct: 364 KARQLMSLVKPTLTDQ-DFRQCDMVIEAVIENLPLKQKIFCELERICKPDCILSTNTSTI 422
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
MK+ +++ +H +P + + L EI+ T ++ T + ++I + PV +
Sbjct: 423 DITKIAAKMKNPERIVGAHFFSPAHVMQLFEIIRTDATPAQILVDTLGLSKQIKKTPVVV 482
Query: 590 SREIDGFVLNRI 625
GF +NRI
Sbjct: 483 G-NCTGFAVNRI 493
>UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 443
Score = 66.1 bits (154), Expect = 7e-10
Identities = 51/191 (26%), Positives = 87/191 (45%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+VG++G+G +G AM FA+VG VT+ D + + ++ + G L
Sbjct: 43 RVGVIGAGTMGGGIAMSFANVGIPVTVCDTDGAALERGLERVRRNYEFSVARGRLDAATM 102
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
A + ++ DL +KDA V E V E++ LK+ +F+ LD +V + I
Sbjct: 103 A-ARLALIRAAVDLQ-DLKDADLVIEAVFEDMALKQDIFRKLDAIVHPDAILATNTSGLD 160
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ V+ +H +P + L+E+V T PEV ++ +G+ V LS
Sbjct: 161 IDEIAVVTRRPQDVVGAHFFSPAHVQKLLEVVRGARTAPEVIATLMSLGRRMGKVSV-LS 219
Query: 593 REIDGFVLNRI 625
R GF+ N +
Sbjct: 220 RIYPGFIGNAL 230
>UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=13;
Clostridia|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Clostridium difficile
Length = 281
Score = 65.7 bits (153), Expect = 9e-10
Identities = 54/198 (27%), Positives = 84/198 (42%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
K+ ++GSG +G FAS G+ V L + I +A + L L G
Sbjct: 2 KLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTKGKWMKATK 61
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
A E V T + +KD + E E++ +KK VF+ LD + ++TI
Sbjct: 62 A-EILSHVSSTTNYE-DLKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILATNTSSLS 119
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ K +VI H NP + LVE++ T + + I + PV +S
Sbjct: 120 ITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVTFDTVFELSKSINKVPVDVS 179
Query: 593 REIDGFVLNRIQYAILGE 646
E GFV+NRI ++ E
Sbjct: 180 -ESPGFVVNRILIPMINE 196
>UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD
binding domain; n=2; Azotobacter vinelandii|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain -
Azotobacter vinelandii AvOP
Length = 208
Score = 65.3 bits (152), Expect = 1e-09
Identities = 46/181 (25%), Positives = 81/181 (44%), Gaps = 3/181 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+ I+GSG +G A A G++V L +Q+ + +A + L GL+ A
Sbjct: 6 IAILGSGSMGVGIATHLARHGHEVLLIYPSMEQLAEVLAMARSILA-----GLVEAGRFA 60
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQ---ECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
EQ + +KD V+ E +PE +ELK+ ++ L+ +VD +
Sbjct: 61 PEQVAATLARLRTSTRLKDVAGVRLLIETLPERIELKRALYAELERIVDAEAVIASDTGG 120
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
E M+H +++++H +PP+ VPLV +V T+ E R ++ E V
Sbjct: 121 LSPERLAEGMRHPGRLLIAHFRSPPHRVPLVAVVAGRQTRSEHLAYVRTLLAGTNLEVVV 180
Query: 587 L 589
+
Sbjct: 181 V 181
>UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=5; Gammaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Serratia proteamaculans 568
Length = 506
Score = 64.9 bits (151), Expect = 2e-09
Identities = 47/201 (23%), Positives = 86/201 (42%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+V ++G+G +G A + A+ G+QV LFD+ A+ + +L+ G + +
Sbjct: 9 RVAVIGAGTMGIGIAQVAAAAGHQVQLFDIAASAARQALGALAQRLRQRVAAG--KADAT 66
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
E + ++ D+ V E V E L +K+ +F+ L+ + T+
Sbjct: 67 TTEALLARIQPAESLNSLADSGLVIEAVAEKLAIKQSLFRELEALCSPATLFASNTSSLS 126
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
++H ++ H NP + LVEIV T E + + + G++ V L
Sbjct: 127 ITAIAGALQHPQRLAGLHFFNPAPLMKLVEIVSGLDTSTETVATLQRLTRQWGKQSV-LC 185
Query: 593 REIDGFVLNRIQYAILGEVWR 655
R GF++NR+ E R
Sbjct: 186 RSTPGFIVNRVARPFYAEALR 206
>UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=2; Aspergillus|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Aspergillus clavatus
Length = 307
Score = 64.9 bits (151), Expect = 2e-09
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 2/199 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG--LLRGNL 229
V ++G G++GR M++A+ G+ V L+ EK A+A +K + L + LL G
Sbjct: 16 VAVIGGGVLGRRLCMMWAAAGHTVQLY---EKSPEVAVAALKYIHEALPQQASKLLLGK- 71
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A V L AV++A V E +PE L LK ++F LD + + I
Sbjct: 72 KAGHGIGHVSPASSLETAVQNAWMVIEAIPELLPLKIELFGQLDQLAPADCILATNSSSY 131
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
E + +A+V +H PP L EI+ +T P + G PV
Sbjct: 132 KSREMLEKVARRARVCNAHYYMPPEQNHL-EIMTCGFTDPAIISFLLEQAAAAGFVPVHA 190
Query: 590 SREIDGFVLNRIQYAILGE 646
E G + NRI AI E
Sbjct: 191 KVESTGLIFNRIWAAIKRE 209
>UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep:
Enoyl-CoA hydratase - Rhodopseudomonas palustris
Length = 699
Score = 64.5 bits (150), Expect = 2e-09
Identities = 52/191 (27%), Positives = 84/191 (43%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+V I+G+G +G AM FA+ G VTL + E+Q+ + ++ + G L +
Sbjct: 297 RVAIIGAGTMGGGIAMSFANAGIPVTLIETGEEQLKRGLGIMQKNWEATAARGGLPPDAP 356
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
A ++ + G L VKDA + E V E + +KK+VF +D +
Sbjct: 357 A-KRMALITGLVGLE-NVKDADLIIEAVFETMAVKKEVFTAVDAHAKPGAVLASNTSYLS 414
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
K V+ H +P + L EIV T P+ +I ++I + PV +
Sbjct: 415 IDEIAATTKRPQDVLGMHFFSPANVMKLCEIVRGAKTAPDALLTAVSIAKKIAKVPVVVG 474
Query: 593 REIDGFVLNRI 625
DGFV NR+
Sbjct: 475 -VCDGFVGNRM 484
>UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Frankia sp. (strain CcI3)
Length = 624
Score = 64.5 bits (150), Expect = 2e-09
Identities = 52/200 (26%), Positives = 87/200 (43%), Gaps = 3/200 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VG+VGSG + A + A G+ V L E+ + +A I+ L + RG L+
Sbjct: 345 VGVVGSGTMAGGIAEVLARSGHDVLLRARSERTLAATLAKIESSLAA----SVARGRLSD 400
Query: 236 DEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
++ V+GT DL + + E V E+L +K+++F +LD + +
Sbjct: 401 ADRLAALARVRGTTDLG-ELGHCELLLEAVVEDLAVKRELFADLDKIAAPGAVLATTTSS 459
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
VI H NP + L+E+VP T +VT A+ G+ PV
Sbjct: 460 LPVIECAMATSRPRDVIGMHWFNPAPAMKLIEVVPTVLTGDDVTATVLALSRAAGRHPV- 518
Query: 587 LSREIDGFVLNRIQYAILGE 646
L + GF++N + + L +
Sbjct: 519 LCADRAGFIVNALLFPYLND 538
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/204 (23%), Positives = 83/204 (40%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 223
+ +VG+VG G +G A + A G +V + + A ++ L + G L
Sbjct: 37 RHRRVGVVGLGTMGAGIAEVLAKAGLEVVGIARDADALARSRARVEHSLDRAGRHGKLDD 96
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+ GT +LA AV D V E + E + K+ +F LD + T+
Sbjct: 97 ATREAVLARMRLGT-ELA-AVADCELVIEAIDERMSAKQALFARLDEICPPATVFLTNTS 154
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+V+ +H NP + LVE+V T P V ++ ++G+ V
Sbjct: 155 SLSVTELAAGTARPERVLGTHWFNPAPVMRLVEVVRTVVTDPTVLAGVIGLVNDVGKTAV 214
Query: 584 TLSREIDGFVLNRIQYAILGEVWR 655
++ + GF++N + + L R
Sbjct: 215 -VAEDRAGFIVNALLFGYLNNAVR 237
>UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 278
Score = 64.5 bits (150), Expect = 2e-09
Identities = 51/200 (25%), Positives = 84/200 (42%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+ ++G+G +GRS A A G++ L D++ + A I+ +L G + A
Sbjct: 7 IAVIGAGTMGRSIAQAAAVGGFRTILEDILPNALRKAEDAIRAELGRAVSTGSVEQR-EA 65
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
D ++ +L A +DA V E VP+ LE K ++F LD V T+
Sbjct: 66 DAALARIEYASNLEDAARDADMVIEAVPDELESKLEIFVLLDKVCRPETMIVSHTQIQSI 125
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+ + I PP +EIV T E A+ + + +EP+ L R
Sbjct: 126 TELASVIYRAPKCIAMWFPKPPQTSVALEIVRGLETSDETATAAVAVAQRMKREPILL-R 184
Query: 596 EIDGFVLNRIQYAILGEVWR 655
E G + R+Q I E ++
Sbjct: 185 ETPGAITARMQALISNEAFK 204
>UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=5; Burkholderiales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 511
Score = 64.5 bits (150), Expect = 2e-09
Identities = 49/188 (26%), Positives = 82/188 (43%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
+VG+G++G A + A G+ V L+D E +A + L L G L +
Sbjct: 17 VVGAGVMGVGIAQVAAQAGHAVMLYDAREGAAAEAKTKLAKSLDALVAKGKLTAQ-GVSQ 75
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
++ LA A A V E + E L++K+ +FQ L+ +V + +
Sbjct: 76 TLSRIEAIASLAAAAP-ARLVIEAIVEKLDVKRGLFQQLEAIVAADCVLATNTSSISVTA 134
Query: 422 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREI 601
++H A+++ H NP + LVE+V T P V + G+ V +R
Sbjct: 135 IANGLQHPARLVGMHFFNPVPQMRLVEVVSGLQTDPAVAALIFDLAGVWGKVAVH-ARST 193
Query: 602 DGFVLNRI 625
GF++NRI
Sbjct: 194 PGFIVNRI 201
>UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 687
Score = 64.1 bits (149), Expect = 3e-09
Identities = 55/194 (28%), Positives = 85/194 (43%), Gaps = 3/194 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
K+ IVG G +G A SVG V L + DAIA + + TL GL RG L+
Sbjct: 284 KIAIVGGGTMGAGIAYACLSVGLPVVLLET----DADAIARAQHNIDTLIGAGLKRGRLD 339
Query: 233 ADEQFQCVKGTCDLA---IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
D ++ L A DA V E E++++KK +F LD V +T+
Sbjct: 340 -DSGAAALRDRLTLTEDYAAASDATLVIEAAFESMDVKKDIFAKLDAAVSPDTVLATNTS 398
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ + ++++ H P + + L+EIV T A+ + + + PV
Sbjct: 399 YLDVDVLAASTRDPSRILGLHFFAPAHIMRLLEIVTGAETSDRALATGYALAKLLKKVPV 458
Query: 584 TLSREIDGFVLNRI 625
L+ DGF+ NRI
Sbjct: 459 -LAGVCDGFIGNRI 471
>UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 287
Score = 64.1 bits (149), Expect = 3e-09
Identities = 47/201 (23%), Positives = 87/201 (43%), Gaps = 1/201 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VG++G+G +G + A GY+V D E+ + A ++ L++ + G L A
Sbjct: 5 VGVLGTGTMGAGIVQVAARAGYRVVACDASEEALGKARRYVRSGLESFARRGALSEE-EA 63
Query: 236 DEQFQCVKGTCDLA-IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
+ V+ T + +A +A+ E + E + KK+ F LD ++ + +
Sbjct: 64 EAALGRVRWTTAMEELAGSEAVI--EAIVERVGPKKEAFAALDALLPPDALLLTNTSSIS 121
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+V +H PP VE+V T E ++ R ++ G+ PV +
Sbjct: 122 ITELASATGRPERVCGAHFFTPPPLREAVEVVRGEQTSDETVERVRRLLSSFGKLPVVVR 181
Query: 593 REIDGFVLNRIQYAILGEVWR 655
+++ GF NR+ +L E R
Sbjct: 182 KDVPGFAANRLLMPVLLEAAR 202
>UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=14; Staphylococcus|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Staphylococcus aureus subsp. aureus JH9
Length = 753
Score = 64.1 bits (149), Expect = 3e-09
Identities = 52/202 (25%), Positives = 89/202 (44%), Gaps = 3/202 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFD-VVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
KV ++G+G +G A LF + G +V L D VV+K + IA K K +K L +L
Sbjct: 5 KVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLIAK-KSYDKITDKKRPLLFDL 63
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
N G D + DA E V E++E+K V+Q + ++ +
Sbjct: 64 NLVSHL--TYGNFDDDLVNDDADLYIEAVKEDIEIKHAVWQQVLQHAKEDALFATNTSGI 121
Query: 410 XXXXXXE--NMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ N K + + H NPP + LVE++P TK + + + + + V
Sbjct: 122 PINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSHTKESIILDVKNFAQNVLGKGV 181
Query: 584 TLSREIDGFVLNRIQYAILGEV 649
+ ++ GFV NR+ + ++
Sbjct: 182 IVVNDVPGFVANRVGTQTMNDI 203
>UniRef50_Q5LVG3 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=2; Rhodobacteraceae|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 681
Score = 63.7 bits (148), Expect = 4e-09
Identities = 57/193 (29%), Positives = 89/193 (46%), Gaps = 2/193 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+V IVG GL+G AM G VT V+E+ A A + ++ L G+ RG ++
Sbjct: 288 RVAIVGGGLMGAGVAMACLGGGLSVT---VIERDAAAAQA-AQERVAGLVAAGVKRGKIS 343
Query: 233 ADEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
D Q + T D DA E V E+L++K+ VF +L V+ + I
Sbjct: 344 PDAQADMLARLATTDTYADASDADLAIEAVFEDLDVKRIVFADLAAVMRPDAILATNTSY 403
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+ + A+ + H +P + + L+EIV P T PEV A+ + + + V
Sbjct: 404 LDPQLVFAGIANPARCLGLHFFSPAHVMKLLEIVKTPDTAPEVLATGFALGKRLRKISV- 462
Query: 587 LSREIDGFVLNRI 625
LS DGF+ NR+
Sbjct: 463 LSGICDGFIGNRM 475
>UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=34;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 298
Score = 63.7 bits (148), Expect = 4e-09
Identities = 53/198 (26%), Positives = 92/198 (46%), Gaps = 4/198 (2%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 223
K ++VG++G+G++G A + A V +F+ + + I L++L++ G+ G
Sbjct: 5 KIQRVGVIGAGIMGAGIAEVCARAHVDVLVFEQTRELAAAGRSRI---LRSLDR-GVSSG 60
Query: 224 NLNADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDD-NTIXX 391
+ E+ Q ++ T DL D V E V E+ ++K ++F LD VV D N +
Sbjct: 61 KITEREREQAAWRLRFTSDLG-DFADRQLVVEAVVEDEKVKSEIFTELDQVVTDPNAVLA 119
Query: 392 XXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIG 571
K +VI H NP +PLVE+V T V+++ A ++
Sbjct: 120 SNTSSIPIMKLGIATKSPERVIGMHFFNPVPVLPLVELVTTLKTSKSVSERAEAFASDVL 179
Query: 572 QEPVTLSREIDGFVLNRI 625
+ V S + GFV+N +
Sbjct: 180 GKQVVRSADRSGFVVNAL 197
>UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 517
Score = 63.3 bits (147), Expect = 5e-09
Identities = 43/188 (22%), Positives = 85/188 (45%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V ++G+G++GR A L A+ G V L D ++ ++ A+ + L G + A
Sbjct: 11 VRVIGTGVMGRGIAQLAAAAGLTVELADARQEAVSAAVDHVGEMFGKLVGKGRMSAE-EA 69
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
D ++ D V E V E+L+ K+++F L+ V + +
Sbjct: 70 DAATARLRPVGDPLAPADSCDLVVEAVREDLDTKRELFAGLEEVCPRHAVLATNTSSLSV 129
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+ +++I H NP + LVE++P T+ +++ ++ +G +PV L+
Sbjct: 130 TAIGAALADPSRLIGLHFFNPVPLMKLVEVIPGARTRQDLSADLVELVRRLGHQPV-LAT 188
Query: 596 EIDGFVLN 619
+ GF++N
Sbjct: 189 DTPGFLVN 196
>UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A277A UniRef100 entry -
Xenopus tropicalis
Length = 666
Score = 62.9 bits (146), Expect = 6e-09
Identities = 52/198 (26%), Positives = 85/198 (42%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KVGIVG+G +G AM FA+VG + +V ++ + + ++ + G L
Sbjct: 292 KVGIVGAGTMGGGIAMNFANVGIPTVVVEVNDETLQRGLGLVRRNYEASAAKGRLTAEQV 351
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
A + ++G D A A+ + V E V EN+ LK+ + L V I
Sbjct: 352 AG-RMALLQGALDYA-ALAECDLVIEAVFENMALKQDICAKLGAVAKPGAIIATNTSTLD 409
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
A V+ H +P + + L+E+V T P+V + IG+ PV +S
Sbjct: 410 VDVLARATGRSADVVGMHFFSPAHVMRLLEVVRGAATAPDVLATIMKLAARIGKVPV-VS 468
Query: 593 REIDGFVLNRIQYAILGE 646
GF+ NR+ + E
Sbjct: 469 GVCYGFIGNRMAEVYMRE 486
>UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme; n=3; Bordetella|Rep: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme - Bordetella pertussis
Length = 705
Score = 62.5 bits (145), Expect = 9e-09
Identities = 46/188 (24%), Positives = 82/188 (43%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
+VG+G +GR A+ A G +V DV + + A+ I+ ++L G + A +
Sbjct: 308 VVGAGTMGRGIAIALADAGLRVRFIDVEQASLDRALEAIRAHYRSLAARGRMT-EAAARD 366
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
+ D+ A +A V E E+L +K+ +F+ LD++V +
Sbjct: 367 AVARISPASDMQ-AAAEADVVVEAAFEDLAIKQAIFRQLDSIVRPGAVLATNTSTLDVDA 425
Query: 422 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREI 601
+ V+ +H +P + L+E+V T P A+ +G+ VT+
Sbjct: 426 IAAATRRPQDVVGTHFFSPANVMRLLEVVRGARTAPRTLGAVLALGRRMGKVCVTVG-VC 484
Query: 602 DGFVLNRI 625
DGFV NR+
Sbjct: 485 DGFVANRM 492
>UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Kineococcus radiotolerans
SRS30216|Rep: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 681
Score = 62.5 bits (145), Expect = 9e-09
Identities = 53/205 (25%), Positives = 93/205 (45%), Gaps = 1/205 (0%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLR 220
K VG+VG+GL+ A+L + V L DV ++ + ++ + L + G +
Sbjct: 317 KVTSVGVVGAGLMASQLALLLLHRLQVPVVLTDVSPDRVEKGVGFVREGVAELLRKGRVS 376
Query: 221 GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
+ A+ V G+ D + A+ DA FV E V E L +K+ V + L+ ++ + +
Sbjct: 377 PD-TANRLSASVSGSVDKS-ALADADFVVEAVFEELAVKQDVLRELEPLLRPDAVIATNT 434
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
++H + + H NP +PLVE+V P T E + T + ++
Sbjct: 435 SSLSVTAMASVLEHPQRFVGFHFFNPVAVLPLVEVVRTPET-DEASLATAFAVGARLKKT 493
Query: 581 VTLSREIDGFVLNRIQYAILGEVWR 655
L ++ FV+NRI + EV R
Sbjct: 494 CVLVQDAPAFVVNRISTRMFDEVVR 518
>UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 765
Score = 62.5 bits (145), Expect = 9e-09
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 2/194 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
EKV ++G+G++G A A+ G +V L DV + A AD ++ + ++ G +
Sbjct: 6 EKVAVLGAGVMGAGIAAHLANAGVRVVLLDVDK-----AAADAGIR-RARDEGGFMDPAF 59
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A + DL++ + DA ++ E +PE L LK+ +++ L + +I
Sbjct: 60 AA--RIATGSTVRDLSL-LADADWIVEALPERLALKQSLYRQLQGIRKPGSILSSNTSTI 116
Query: 410 XXXXXXENMK--HKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
M A +++H NPP + L+E+V P T+PE+ + + V
Sbjct: 117 PLAALVGGMAGDFAADFLITHFFNPPRRMRLLELVAGPATRPEIVALITDFCDRRLGKDV 176
Query: 584 TLSREIDGFVLNRI 625
R+ GF+ NRI
Sbjct: 177 VSCRDTPGFIANRI 190
>UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Picrophilus torridus|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Picrophilus torridus
Length = 273
Score = 62.5 bits (145), Expect = 9e-09
Identities = 49/200 (24%), Positives = 97/200 (48%), Gaps = 2/200 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+V ++G+G +G A +FA ++V L DV + + I+ L+ ++ G ++ +
Sbjct: 2 RVTVIGAGTMGSGIAEVFALNNHEVLLSDVSNDILNNGRKKIEASLEKFKEKGRIK---S 58
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNL--DNVVDDNTIXXXXXXX 406
++ + + D+ D +++ E V E +++K+ V + D+++ NT
Sbjct: 59 VEDVLEKISMNTDINAQESD-LYI-EAVLERIDVKRDVLSRIRSDSIIATNT------SS 110
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+ +++ + I H NPP + L+EIV T E TK+ I +G+ PV
Sbjct: 111 ISITYLSKFVRNPEKFIGMHFFNPPPIMSLIEIVRGNSTSDETTKRIVDISRSLGKTPVE 170
Query: 587 LSREIDGFVLNRIQYAILGE 646
++ + GFV NR+ A+L E
Sbjct: 171 VN-DFPGFVSNRVLMAMLRE 189
>UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16;
Bacillaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 795
Score = 62.1 bits (144), Expect = 1e-08
Identities = 53/213 (24%), Positives = 94/213 (44%), Gaps = 17/213 (7%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIA---------DIKVQLKTLEK 205
+ ++GSG++G A A+VG L D+V +++T ++ +L
Sbjct: 7 RAAVLGSGVMGSGIAAHLANVGIPTLLLDIVPRELTKEEEAKGWTLEHKQVRNRLANQAL 66
Query: 206 DGLLRGN----LNADEQFQCVKGTC-DLAIAVKDAIFVQECVPENLELKKKVFQNLDNVV 370
+ LL+ ++ D G D + + ++ E V E LE+KK+VF +D V
Sbjct: 67 ERLLKQKPAPLMSKDNIALIETGNFEDDFHRLAEVDWIIEAVVEKLEVKKEVFARVDEVR 126
Query: 371 DDNTIXXXXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 544
TI E K + +H NPP Y+ L+EI+P T P+V
Sbjct: 127 TPGTIVSSNTSGISIAAMAEGRSDDFKKHFLGTHFFNPPRYLKLLEIIPTEHTDPDVVAY 186
Query: 545 TRAIMEEIGQEPVTLSREIDGFVLNRI-QYAIL 640
++ E++ + V ++++ F+ NRI Y +L
Sbjct: 187 MKSFGEDVLGKGVVMAKDTPNFIANRIGTYGLL 219
>UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:
Dehydrogenase - Fusarium sporotrichioides
Length = 285
Score = 62.1 bits (144), Expect = 1e-08
Identities = 56/200 (28%), Positives = 88/200 (44%), Gaps = 2/200 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V ++G G++GR A +A+ GY V + D +Q A+ + D +RG++ A
Sbjct: 14 VAVLGGGVLGRRIACGWAASGYDVIIRDPSHEQRVAAVEYCNTSMSKY-PDSNVRGSIQA 72
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
E DL AV A V E VPE L +K F +L+ + ++TI
Sbjct: 73 VE---------DLPEAVAKAWLVIETVPEKLPIKIATFTDLERLTSEDTILCSNSSSYKS 123
Query: 416 XXXXENMK--HKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+++ K +V+ H PP Y +VE++ T + +EEI P
Sbjct: 124 REMVGDLRPDTKRRVLNMHYYLPPDY-RVVELMTDGETDESIFPFLSEKLEEIRFHPYVA 182
Query: 590 SREIDGFVLNRIQYAILGEV 649
+E GF+ NR+ AI EV
Sbjct: 183 RKESTGFIYNRLWAAIKREV 202
>UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Actinosynnema pretiosum subsp. auranticum
Length = 341
Score = 61.7 bits (143), Expect = 1e-08
Identities = 46/198 (23%), Positives = 82/198 (41%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
++G+G++G L S G V L D ++ A AD++ L+T + G+ G L
Sbjct: 62 VLGAGVMGCGITALALSRGLPVLLVDPDADRLDAARADVRAHLRTAQLLGVAAGPLGELT 121
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
G ++ + V E V E+ E K K + V T
Sbjct: 122 TATDTGGP-------REVVAVVEAVTEDAETKAKALTGVCATVPPGTPLVSNTSSIPMGE 174
Query: 422 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREI 601
+ ++ +H +NPPY +P VE+ P T A++ +G+ PV + +
Sbjct: 175 LAPALPRPGDLVGAHFMNPPYLIPAVEVARGPLTSDAAFAGLTALLARLGRAPVQVG-DA 233
Query: 602 DGFVLNRIQYAILGEVWR 655
GFV +R+ + ++ + R
Sbjct: 234 PGFVTSRLLHPMINDAAR 251
>UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation
multifunctional protein (MFP) [Includes: Enoyl-CoA
hydratase/3-2-trans-enoyl-CoA isomerase/3-
hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.3.3.8)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]; n=23; Magnoliophyta|Rep: Peroxisomal fatty
acid beta-oxidation multifunctional protein (MFP)
[Includes: Enoyl-CoA hydratase/3-2-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Oryza sativa subsp.
japonica (Rice)
Length = 726
Score = 61.7 bits (143), Expect = 1e-08
Identities = 50/193 (25%), Positives = 82/193 (42%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 223
K KV ++G GL+G A V L +V + + I L+ L K G L
Sbjct: 308 KIRKVAVIGGGLMGSGIATALLVSNTSVVLKEVNPQFLQRGQKMIAANLEGLVKRGSLTK 367
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+ ++ +KG D + KD V E V E + LK+ +F +L+ V + I
Sbjct: 368 D-KMNKAMSLLKGALDYS-DFKDVDMVIEAVIEKIPLKQSIFSDLEKVCPPHCILATNTS 425
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
E + ++I +H +P + +PL+EIV T P+ + + I + PV
Sbjct: 426 TIDLNVVGEKTNSQDRIIGAHFFSPAHIMPLLEIVRTEKTSPQAILDLITVGKMIKKVPV 485
Query: 584 TLSREIDGFVLNR 622
+ GF +NR
Sbjct: 486 VVG-NCTGFAVNR 497
>UniRef50_Q5LVD0 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=6; Rhodobacterales|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 698
Score = 61.3 bits (142), Expect = 2e-08
Identities = 53/193 (27%), Positives = 82/193 (42%), Gaps = 3/193 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+G++G G +G A G VT+ ++ + A I+ L L RG L A
Sbjct: 292 IGVIGGGTMGAGIATAALLSGLSVTMLEMTPEAAEAAKGRIEGNLS----GALKRGKLTA 347
Query: 236 DEQFQCVKGTCDLAI---AVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
+ LAI A+ DA V E V E++E+KK+VF LD V +
Sbjct: 348 QQFDNLTTKALTLAIDYDALADADLVIEAVFEDMEVKKQVFTKLDAVCKPGAVLASNTSY 407
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
V+ H +P + + L+E+V A T P+V A+ + +G+ V
Sbjct: 408 LDINQIAAVTSRPQDVLGLHFFSPAHVMKLLEVVIADQTAPDVAATGFALGKRLGKVSVR 467
Query: 587 LSREIDGFVLNRI 625
+ DGF+ NRI
Sbjct: 468 -AGVCDGFIGNRI 479
>UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:
PlmT8 - Streptomyces sp. HK803
Length = 571
Score = 61.3 bits (142), Expect = 2e-08
Identities = 52/199 (26%), Positives = 81/199 (40%), Gaps = 1/199 (0%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
+ ++G+VGSG + A A GY TL E + +A+A ++ L + G L
Sbjct: 290 ARRIGVVGSGTMATGIAQACARAGYPTTLVARSEVRAKEALATVENSLNRAVQRGRLTPE 349
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
+ + G L AV V E V E++++K+ VF+ LD V T+
Sbjct: 350 -QLTSSMESLTGVSRLE-AVAACDLVVEAVVEDIDVKRTVFRELDAVCGAQTVLATSTSS 407
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV- 583
V+ H NP + LVE+V T E A +G+ PV
Sbjct: 408 LPVIECAMATGRPEAVVGMHFFNPAPVMKLVEVVRTALTSRETLGVAHATATALGKRPVG 467
Query: 584 TLSREIDGFVLNRIQYAIL 640
L R GF++N + + L
Sbjct: 468 CLDR--SGFIVNALLFPYL 484
Score = 34.7 bits (76), Expect = 2.0
Identities = 31/134 (23%), Positives = 51/134 (38%), Gaps = 5/134 (3%)
Frame = +2
Query: 260 GTCDLAIAVKDAI---FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXE 430
GT DL D + V E VPE ++ K ++ + N +
Sbjct: 54 GTIDLTTRSADIVSADLVIEAVPERMKTKCELLSHAHNACAPGAVFATTTSGLAVTDIAF 113
Query: 431 NMKHKAQVIVSH--PVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREID 604
+ + H P P VE+V P T V +A++ ++GQ PV++ +
Sbjct: 114 GSGRPCRTVGLHLFPQGPMDPATAVEVVGTPLTDGSVLADVQALIRDLGQVPVSVP-DRA 172
Query: 605 GFVLNRIQYAILGE 646
GFV + A L +
Sbjct: 173 GFVGGALTMAYLND 186
>UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=4; Brucella|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 501
Score = 60.9 bits (141), Expect = 3e-08
Identities = 47/191 (24%), Positives = 82/191 (42%), Gaps = 2/191 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KV I+GSG++G A A+ G V LFD Q+ D + K+ L + + RG L
Sbjct: 8 KVAIIGSGVMGAGIAETMAAGGIDVLLFD----QMADKASAAKLALSHRLQSRVERGKLG 63
Query: 233 ADEQFQCVKGTCDLAIA--VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
AD Q ++ + + A V E + ENL +KK + L+ ++ +
Sbjct: 64 ADRAAQILERIVPVQQLDEIVSADLVVEAIVENLTVKKDLVAALEAILPRQAVIATNTSS 123
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+ K+ ++ H NP + +VE++ T V + + +G PV
Sbjct: 124 LSVTAIAASAKYPERIAGFHFFNPVPLMRVVEVIKGALTGDAVVDALKELAVRVGHRPVN 183
Query: 587 LSREIDGFVLN 619
+ + GF++N
Sbjct: 184 -ATDTPGFIIN 193
>UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase; n=18;
Bacteria|Rep: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase - Deinococcus
radiodurans
Length = 708
Score = 60.5 bits (140), Expect = 3e-08
Identities = 48/192 (25%), Positives = 85/192 (44%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ GI+G+G +G AM F +VG VT+ + ++ + + I+ + K G + +
Sbjct: 308 KSAGIIGAGTMGGGIAMNFLNVGIPVTIVETSQEALDRGLGVIRKNYENTAKKGRMTQD- 366
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ +++ + T + + A + E V EN+++KK +F LD + I
Sbjct: 367 DVEKRMGLLTPTLKME-DLAGADIIIEAVFENMDVKKDIFTRLDKIAKPGAILASNTSTL 425
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
QVI H +P + L+EIV A T V + A+ + I + V +
Sbjct: 426 DVNEIASVTGRPEQVIGLHFFSPANVMKLLEIVRADKTSDSVLATSLALAKRIKKVGVVV 485
Query: 590 SREIDGFVLNRI 625
DGFV NR+
Sbjct: 486 G-VCDGFVGNRM 496
>UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n=1;
Geobacter metallireducens GS-15|Rep: 3-hydroxyacyl-CoA
dehydrogenase-like - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 290
Score = 60.5 bits (140), Expect = 3e-08
Identities = 55/207 (26%), Positives = 92/207 (44%), Gaps = 5/207 (2%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+KV I+G+G++G A+ A GY V L +V + I+ L + G L +
Sbjct: 5 KKVAILGAGMMGSDIALSCALAGYDVLLKEVSLDLAAAGVERIRGSLAKWSEKGRLA--V 62
Query: 230 NADEQFQCVKGTC--DLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+A++Q V D D V E + E+L++K + F+ L+ V + I
Sbjct: 63 DAEQQKSAVARITPVDNFSGFGDVDLVIEAIFEDLDVKSQNFRQLEEVCKPSCIIASNTS 122
Query: 404 XXXXXXXX---ENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQ 574
+ + K++ + H +P + LVE+V T E + A IG+
Sbjct: 123 SLPITKLGACFSSAERKSRFVGMHFFSPAAIMKLVEVVNGEDTSAETVETACAFCTSIGK 182
Query: 575 EPVTLSREIDGFVLNRIQYAILGEVWR 655
EP+ ++ + GFV+NRI AI E R
Sbjct: 183 EPIKVN-DCAGFVVNRILGAINDEAIR 208
>UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Polynucleobacter sp.
QLW-P1DMWA-1|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 310
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/116 (29%), Positives = 59/116 (50%)
Frame = +2
Query: 302 VQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPP 481
V E V ENL LK+ +F +LD + + ++ ++ +H P
Sbjct: 79 VIESVSENLGLKRLIFSDLDQRLPSHIPIGSNTSGFPISDITASLPTAHRMFNTHYFMPA 138
Query: 482 YYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREIDGFVLNRIQYAILGEV 649
+ VPLVE+V + PE+ K + + ++PV + ++I GF+ NRIQ+A++ EV
Sbjct: 139 HIVPLVEVVLGKTSDPELAKTVCQLFQAHHKKPVLVKKDIPGFLANRIQHALMREV 194
>UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 293
Score = 60.5 bits (140), Expect = 3e-08
Identities = 50/201 (24%), Positives = 89/201 (44%), Gaps = 3/201 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VG++G G +G +FA+ G V + + + +I +A I L T G+ +G L+
Sbjct: 11 VGVLGLGTMGAGITQVFAASGRDVVVLEADQDRIDAGLASISAFLDT----GVAKGKLSE 66
Query: 236 DEQ---FQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
++ + T D+ + D V E V EN E+KK + + VV NT
Sbjct: 67 TDKSGLLARITATTDVT-DLADVDLVVESVTENAEVKKDLLGRVAAVVGVNTPICTNTSA 125
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+ + ++V H NP VE+V A T E+ + A+++ +G +
Sbjct: 126 LSVTELAAALPNPSRVAGLHFFNPAPLQRTVEVVRALQTGEELVDRLVALVDTLGNKDPI 185
Query: 587 LSREIDGFVLNRIQYAILGEV 649
+ ++ GF+LN + L +V
Sbjct: 186 VVKDRPGFLLNALLLPYLNDV 206
>UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 336
Score = 60.1 bits (139), Expect = 5e-08
Identities = 53/220 (24%), Positives = 98/220 (44%), Gaps = 11/220 (5%)
Frame = +2
Query: 29 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 208
M++ + ++ ++G+G +G+ A++FA G VTL D + DA+ +T ++
Sbjct: 1 MSAAAEVTRIHVLGAGRMGQGIALVFAFAGIDVTLIDFKRR---DAVGQSAFDDRTRDEI 57
Query: 209 G------LLRGNLNADEQFQCVKGTCDLAI-----AVKDAIFVQECVPENLELKKKVFQN 355
+ G ++A + V +A AV+DA V E +PE L+ K +
Sbjct: 58 ARPLHAQVALGRIDAAQADAVVARIAIVARDGAAEAVRDADIVFEALPEVLDAKADALRW 117
Query: 356 LDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 535
L VD ++ +++ +H +NP +PLVEI + T V
Sbjct: 118 LGEHVDARATIASTTSTFVVTELQRHVVRPERMLNAHWLNPALLMPLVEISRSDATDQSV 177
Query: 536 TKKTRAIMEEIGQEPVTLSREIDGFVLNRIQYAILGEVWR 655
A++E +G++PV + G+++ RIQ + E R
Sbjct: 178 VDALAALLERVGKKPV-ICGPAPGYIVPRIQALAMNEAAR 216
>UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 283
Score = 60.1 bits (139), Expect = 5e-08
Identities = 46/197 (23%), Positives = 83/197 (42%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+ ++G G IG S A A G+ V + + E + A + L
Sbjct: 6 IAVIGGGNIGSSLAFDCALRGHNVVVVEKDEPSCEQSRARVLETAGYAPLFSPLAKGKKP 65
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
+ ++ + +L A+ D FV E +PEN+ELK+ ++ + + N +
Sbjct: 66 QDILDNIRWSNELG-AISDCAFVVENIPENIELKQALYTRMAEFIAPNAVLAANTSCIPI 124
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
K AQVI H +NP Y VE++ T + + ++ +G++ V + +
Sbjct: 125 TKLGSFHKTSAQVIGVHFMNPVYLKHTVEVILGLNTSEQTKDRCLEMLAMLGKKAVVV-K 183
Query: 596 EIDGFVLNRIQYAILGE 646
+ GFV NRI + + E
Sbjct: 184 DGPGFVSNRISHLFMNE 200
>UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;
n=4; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - gamma proteobacterium HTCC2207
Length = 718
Score = 60.1 bits (139), Expect = 5e-08
Identities = 52/208 (25%), Positives = 97/208 (46%), Gaps = 4/208 (1%)
Frame = +2
Query: 29 MASKFKSEKV-GIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEK 205
+ASK K G++G+G++G A A GY V + D+ + + I + K L K
Sbjct: 310 LASKLPEIKTAGVIGAGIMGGGIAYQNAIRGYSVVMKDINQPALDLGIQEAN---KLLAK 366
Query: 206 DGLLRGNLNADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDD 376
G+ RG L ++ Q +K + + + + V E V E +KK V ++ ++D+
Sbjct: 367 -GVKRGKLTEEKAGQILSLIKPSLEDSDVAPCNMLV-EAVVELESVKKMVLPAVEALLDN 424
Query: 377 NTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAI 556
+ + E+++ H NP + +PLVEI+ T E A
Sbjct: 425 SAVITSNTSTISINRLAESLERPQNFCGMHFFNPVHAMPLVEIIRGENTSDETIAAVCAY 484
Query: 557 MEEIGQEPVTLSREIDGFVLNRIQYAIL 640
+G++P+ ++ + GF++NR+ +A+L
Sbjct: 485 ALGLGKKPIVVN-DCPGFLVNRVLFAML 511
>UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Vibrio cholerae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Vibrio cholerae
Length = 284
Score = 60.1 bits (139), Expect = 5e-08
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 4/202 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVV--EKQITDAIADIKVQLKTLEKDGLLRGN 226
KV +VG+G++G+ + + +V + +IA + + + K +
Sbjct: 2 KVAVVGNGVMGKGIVEILLCYTKLAGIESIVWISRDTESSIASTSLLSRKVVKFLKTKSE 61
Query: 227 LN--ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
++ E ++ T D + A+K A V E V E+ ++K + + VVDD TI
Sbjct: 62 IDFPPSESMAALQITSDFS-ALKSAELVIEAVSEDKDVKHDIMAKIAAVVDDTTIVASNT 120
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
N + + H NP + LVE+V T + +K IG+EP
Sbjct: 121 SSLSITELAANFRKPENFLGLHFFNPAPMMSLVEVVRGLTTCESIIEKAVVFSRSIGKEP 180
Query: 581 VTLSREIDGFVLNRIQYAILGE 646
V ++ E GFV+NR+ ++ E
Sbjct: 181 VVVN-EAPGFVVNRMLIPMINE 201
>UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit,
mitochondrial-like protein; n=6; Trypanosomatidae|Rep:
Trifunctional enzyme alpha subunit, mitochondrial-like
protein - Leishmania major
Length = 726
Score = 60.1 bits (139), Expect = 5e-08
Identities = 45/204 (22%), Positives = 90/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGNL 229
+VG++G+G++G FA V + D+ E+ + I +++ + + + + ++ L
Sbjct: 309 RVGVIGAGVMGSGIVHYFAKNNIPVAVKDLTEESVKQGITNVRAEFERAVRRKRMVTAEL 368
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNL--DNVVDDNTIXXXXXX 403
D + V G + +DA + E E +++KKKV Q L D ++ ++
Sbjct: 369 --DGKMALVTGGTTNEV-FRDADVIVEAAVEVMDIKKKVIQQLEKDGILHSKSLFATNTS 425
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
K ++ H NP +PLVE++ T E + + G+ P+
Sbjct: 426 SLSLTEMQTVAKCPHNIVGMHFFNPVSKMPLVEVIKGKSTSTEAAAAIFNLALKTGKIPI 485
Query: 584 TLSREIDGFVLNRIQYAILGEVWR 655
++ + GF++NRI + E R
Sbjct: 486 IVN-DGPGFLVNRILGVYMAEAGR 508
>UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative; n=1; Filobasidiella
neoformans|Rep: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 342
Score = 59.7 bits (138), Expect = 6e-08
Identities = 52/208 (25%), Positives = 96/208 (46%), Gaps = 4/208 (1%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFD--VVEKQITDAIADIKVQLKTLEKDGLL 217
K E++ + G+GL+G A + A G +V L D + + + I+ ++ + +
Sbjct: 35 KVEELTVFGAGLMGAGIAQVGAQNGLKVELTDDPAILRNGINIISKSLARVAKKKSPDDI 94
Query: 218 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 397
G N + + T D + AV++A V E + E++++K+ +F LD + I
Sbjct: 95 EGFTN--NVLKNISTTTDSSQAVENADLVVEAIIESIKVKRDLFGFLDGKAKSDCIFATN 152
Query: 398 XXXXXXXXXXE--NMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIG 571
E + + +A+ H NP + LVEI+ P T E + R + ++G
Sbjct: 153 TSSLSVTEIAEACSPERQAKFAGLHFFNPVPAMKLVEIIRTPQTSQETYETLREVTLQMG 212
Query: 572 QEPVTLSREIDGFVLNRIQYAILGEVWR 655
+ PVT + + GF++NR+ L E R
Sbjct: 213 KSPVTCN-DTPGFIVNRLLVPYLLEAIR 239
>UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Marinomonas sp. MED121|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Marinomonas sp. MED121
Length = 545
Score = 59.3 bits (137), Expect = 8e-08
Identities = 45/202 (22%), Positives = 86/202 (42%), Gaps = 2/202 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+G+VG+G +G A + + G++V L+D Q +A K + L + +G +
Sbjct: 17 IGVVGAGAMGAGIAQVASQAGHKVFLYD----QNEEASFRAKESISLLLNKKVAKGTITR 72
Query: 236 DEQFQCVKGTCDL--AIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ C+ L +K A + E + E LE+K+ +F+ L+ + I
Sbjct: 73 EHYDTCIANIIPLHSLDELKSADLIIEAIVETLEIKQSLFRALELICKPECILASNTSSI 132
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+K+ + + H NP +PLVE++ + + K+ G+ PV
Sbjct: 133 SITAIASCLKYPERFLGLHFFNPAPVMPLVEVISGLASDQLIAKQLYDTCLLWGKTPVK- 191
Query: 590 SREIDGFVLNRIQYAILGEVWR 655
++ GF++NR+ E R
Sbjct: 192 TKSTPGFIVNRVARPFYAEALR 213
>UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 296
Score = 59.3 bits (137), Expect = 8e-08
Identities = 49/192 (25%), Positives = 86/192 (44%), Gaps = 3/192 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V ++G+G +G A + A G++ L+D+ E + I + +K L G L+A
Sbjct: 12 VAVLGAGTMGSGIATVMARAGHRTILYDINEANLERGIDTVH---GFFDKSVRL-GKLDA 67
Query: 236 DEQFQCVKGTCDLAIAVKDAI---FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
Q K + + +KD V E V E+L LKK+ F LD++V T+
Sbjct: 68 TAG-QAAKDSLSGSTELKDLAPCDVVVEAVFEDLSLKKETFGRLDDIVPPTTLFHTNTST 126
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+ + +V+ +H NP + LVE+ T K T + +G+ V
Sbjct: 127 LSVTGIASGSRLRERVVGTHYCNPAPLMKLVEVANGRHTADWAHKATLEFLASLGKTSV- 185
Query: 587 LSREIDGFVLNR 622
++++ GF++NR
Sbjct: 186 VTKDRPGFIVNR 197
>UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Comamonas testosteroni KF-1
Length = 706
Score = 59.3 bits (137), Expect = 8e-08
Identities = 55/194 (28%), Positives = 87/194 (44%), Gaps = 3/194 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+VGI+G+G +G AM FA+ G V L + + + +A I+ + + RG L
Sbjct: 307 RVGILGAGTMGGGIAMAFANAGIPVVLCEREQAALDRGMAMIERNYQI----SVSRGGLT 362
Query: 233 AD---EQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
A+ E+ Q ++ T DL+ A + V E V E++ +K+ VF LD + TI
Sbjct: 363 AEAVKERMQHIQQTLDLS-AFAEVDLVIEAVFEDMAIKRDVFVQLDRICRKGTILATNTS 421
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ VI H +P + L+E+V T V + IG+ PV
Sbjct: 422 RLNINEIAAVTQRPEDVIGLHFFSPANVMKLLEVVRGERTCDAVIASCMQMAVAIGKIPV 481
Query: 584 TLSREIDGFVLNRI 625
L +GFV NR+
Sbjct: 482 -LVGVCEGFVGNRM 494
>UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=65; Bacteria|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Bacillus subtilis
Length = 287
Score = 59.3 bits (137), Expect = 8e-08
Identities = 47/200 (23%), Positives = 87/200 (43%), Gaps = 1/200 (0%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 226
+++ + G+G +G A A G+ V ++DV + + +K QL + EK
Sbjct: 4 KQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKRLKKQLARDAEKGKRTETE 63
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
+ + + T + A + A V E + EN+ K ++F+ LD + +TI
Sbjct: 64 VKSVINRISISQTLEEA---EHADIVIEAIAENMAAKTEMFKTLDRICPPHTILASNTSS 120
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+VI H +NP + LVE++ T E A+ E++G+ V
Sbjct: 121 LPITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATSEETALDVMALAEKMGKTAVE 180
Query: 587 LSREIDGFVLNRIQYAILGE 646
++ + GFV NR+ ++ E
Sbjct: 181 VN-DFPGFVSNRVLLPMINE 199
>UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;
n=9; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - Coxiella burnetii
Length = 642
Score = 58.8 bits (136), Expect = 1e-07
Identities = 51/208 (24%), Positives = 98/208 (47%), Gaps = 1/208 (0%)
Frame = +2
Query: 35 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDG 211
+++ +++ ++G+G++G A A G +VTL D ++I AI K L+
Sbjct: 269 TRYLPQQIHVIGAGVMGGDIAAWCALRGIRVTLHDKSAEKIAPAIKRAHALYEKKLKIPR 328
Query: 212 LLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 391
L++ ++ E V+GT VK A + E V E++++K++V ++ + I
Sbjct: 329 LIQAAMDRLEPD--VEGT-----GVKKADLIIEAVFEDIKVKQEVLSAIEPQLKPEAILA 381
Query: 392 XXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIG 571
+K+ +++ H NP +PLVE+ + T ++ +K A + I
Sbjct: 382 TNTSSLSLDELSSVLKNPERLVAIHFFNPVAKLPLVEVASSQQTSADIAEKALAFVGAID 441
Query: 572 QEPVTLSREIDGFVLNRIQYAILGEVWR 655
+ P+ +S GF++NR A L E R
Sbjct: 442 KLPLAVSSS-PGFLVNRALMAYLLEANR 468
>UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 849
Score = 58.8 bits (136), Expect = 1e-07
Identities = 45/206 (21%), Positives = 87/206 (42%), Gaps = 2/206 (0%)
Frame = +2
Query: 14 TLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK 193
T+R S F KV ++G+G++G A + V LFD+ K+ +K ++
Sbjct: 33 TIRRHPVSNFLIRKVAVLGAGVMGAQIAAHLINARVPVLLFDLPAKEGPKNAIALKA-IE 91
Query: 194 TLEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVD 373
+L+K + D ++ D + + V E + E ++ K +++ + +
Sbjct: 92 SLKKLSPAPFGVKDDAKYLEAANYEDDIAKLAECDVVIEAIAERMDWKHDLYKKVAPHIA 151
Query: 374 DNTIXXXXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 547
N I E K++ H NPP Y+ LVE++P T+PE+ +
Sbjct: 152 PNAIFATNTSGLSITKLSEGFSDELKSRFCGVHFFNPPRYMHLVELIPTAHTRPEILDQL 211
Query: 548 RAIMEEIGQEPVTLSREIDGFVLNRI 625
+ I + V +++ F+ NR+
Sbjct: 212 ETFLTSIVGKGVVRAKDTPNFIANRV 237
>UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA
dehydrogenase and acyl-CoA-binding protein; n=11;
Francisella tularensis|Rep: Fusion product of
3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding
protein - Francisella tularensis subsp. tularensis
(strain FSC 198)
Length = 898
Score = 58.8 bits (136), Expect = 1e-07
Identities = 43/194 (22%), Positives = 83/194 (42%), Gaps = 2/194 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+K+ ++G+G +G A FA+ + V LFD+ +Q A I+ L L K
Sbjct: 118 DKIAVLGAGTMGAQIAAHFANAKFPVVLFDLKSQQ-GSANVIIEDSLAKLTKLNPAPFGS 176
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
++ D + D + E V E +++K+ ++ + + + +N I
Sbjct: 177 KDSIKYITPANYEDNLELLADCDLIIEAVAERIDIKESLYTKISSHIKENAILASNTSGL 236
Query: 410 XXXXXXENMKHKAQVIVS--HPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ + +V H NPP Y+PLVE++P T E+ K + E + +
Sbjct: 237 SITKLAQVLPENLKVNFCGVHFFNPPRYMPLVELIPHADTNSEILDKLETFLVEKLGKSI 296
Query: 584 TLSREIDGFVLNRI 625
+++ F+ NR+
Sbjct: 297 IRAKDTPNFIANRL 310
>UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit
FadB; n=1; Blastopirellula marina DSM 3645|Rep: Fatty
oxidation complex, alpha subunit FadB - Blastopirellula
marina DSM 3645
Length = 724
Score = 58.8 bits (136), Expect = 1e-07
Identities = 44/204 (21%), Positives = 88/204 (43%), Gaps = 1/204 (0%)
Frame = +2
Query: 38 KFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLL 217
K K E V ++G+G++G A G TL D + + +A + ++ ++D
Sbjct: 314 KTKIESVSVIGAGIMGAGIAAASIRRGILTTLSDANAEALRRGVAGV-LEEAAYDRDAGK 372
Query: 218 RGNLNADEQFQCVKGTC-DLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 394
+ A E + + D +A + E + ENLE+K+K++ L+ + D+ I
Sbjct: 373 KTIAKAVEGAAMLNASISDSEVAASKLVI--EAIVENLEVKRKIYARLEPQLADDAILAS 430
Query: 395 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQ 574
N+ + + H NP + LVE++ T A + +G+
Sbjct: 431 NTSTLPITQLAANLAKPERFVGIHFFNPVRKMKLVEVIRGAQTSDATVASAVAFAKRLGK 490
Query: 575 EPVTLSREIDGFVLNRIQYAILGE 646
P+ ++ + GF++NR+ + + E
Sbjct: 491 FPIVVN-DGPGFLVNRLLFPYMNE 513
>UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2;
Alphaproteobacteria|Rep: Acetoacetyl-CoA reductase -
Rhodobacterales bacterium HTCC2150
Length = 780
Score = 58.8 bits (136), Expect = 1e-07
Identities = 43/195 (22%), Positives = 90/195 (46%), Gaps = 3/195 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKV-QLKTLEKDGLLRGN 226
+++ ++G+G +G A A+ G++V L D+ K + + + V +L + L+
Sbjct: 7 KRIAVIGAGTMGSGIAGQIANAGHEVLLLDLPGKNSRNEVTENAVTRLLKSDPPALMHKK 66
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
A + ++ D + + ++ E + E L++KK ++Q L++V+ +
Sbjct: 67 RAALIKVGNIEDDFD---KLAECDWIVEAIVERLDIKKALYQRLNDVISPECVVTSNTST 123
Query: 407 XXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
E+M +A+ ++H NP Y+ L+E+V T P V + +EI +
Sbjct: 124 IPIKLLVEDMPQDFRARFAITHYFNPVRYMRLLELVRGADTNPAVMDRLARYNDEILGKG 183
Query: 581 VTLSREIDGFVLNRI 625
V + GF+ NR+
Sbjct: 184 VVQCGDTPGFLGNRV 198
>UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Psychromonas|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychromonas ingrahamii
(strain 37)
Length = 724
Score = 58.8 bits (136), Expect = 1e-07
Identities = 47/198 (23%), Positives = 83/198 (41%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+ ++G+G++G A LF+ V L D+ ++ + L+K + N
Sbjct: 326 QAAVLGAGVMGGGIAWLFSKNEIPVRLKDIEWDAVSKGYQTAALYYGQLKKVHKINEN-K 384
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
+ + GT + K V E V ENLE+KK V + ++ + I
Sbjct: 385 IRVKMNYIAGTVNYN-GFKRIDLVVEAVSENLEVKKTVLEEVEAQLSKQAILASNTSSLS 443
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
N++ I H NP +PLVEI+P T + + ++ G+ P+ ++
Sbjct: 444 ITEMAVNLQRPENFIGMHFFNPVNRMPLVEIIPGEKTSQQTIVTLVKLAKKAGKTPIVVA 503
Query: 593 REIDGFVLNRIQYAILGE 646
GF++NRI + L E
Sbjct: 504 -NCAGFLVNRILISFLNE 520
>UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Geobacter lovleyi SZ|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor - Geobacter
lovleyi SZ
Length = 285
Score = 58.8 bits (136), Expect = 1e-07
Identities = 44/199 (22%), Positives = 81/199 (40%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+G+ G+G +G A L A G++V L+ + DA I+ L L + GL+
Sbjct: 8 IGVAGAGSMGAGIAQLAAMAGFRVRLYARHASALADAAGRIETSLAKLHEKGLIG---EE 64
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
+ C +A+ D V E + E + K ++ L V+ I
Sbjct: 65 PTVIRARISNCHEPVALSDCDLVIEAIAEQMAAKCELLAELGAVLGKEAILASSTSSLSI 124
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+ I H +NP + LVE++ T P R ++ +G++ V S+
Sbjct: 125 TALGAASGIPQRFIGMHFMNPVPLMELVELIAGSETSPRTIDIARQMVTALGKQSV-CSK 183
Query: 596 EIDGFVLNRIQYAILGEVW 652
+ GF++ R+ ++ E +
Sbjct: 184 DQPGFIITRLLCVLINEAF 202
>UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 304
Score = 58.8 bits (136), Expect = 1e-07
Identities = 48/194 (24%), Positives = 86/194 (44%), Gaps = 2/194 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
EK+G+VG GL+G FA G +V DV E+++ + IK L++ + +G +
Sbjct: 3 EKIGVVGFGLMGTQITQFFAQQGLEVVAIDVSEERLRKGMEAIKAGRFGLQR-LVEKGKI 61
Query: 230 NADEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+E + T A+KD V E V E++ LK KV + +D V D +
Sbjct: 62 TEEEMNAVLSRISTSTSHSALKDCDLVIEAVFEDVNLKLKVLREIDAVTD--AVIGSNTS 119
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ + + + H NP LVE+V + ++ R ++G+ P+
Sbjct: 120 SISITKLSSAVSNPERFLGIHFFNPAQIQKLVELVKGLLSDEKLVNGIRDWFLKLGKVPI 179
Query: 584 TLSREIDGFVLNRI 625
++ + GF +R+
Sbjct: 180 VVN-DSPGFATSRL 192
>UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Sphingomonas wittichii RW1
Length = 489
Score = 58.0 bits (134), Expect = 2e-07
Identities = 44/190 (23%), Positives = 83/190 (43%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+ +VG+G +G A++ A G+ V + D + + + L +L K G + A
Sbjct: 9 IAVVGAGTMGAGIALVAAQAGHAVRVIDTQDAALDRGRQSVARSLASLVKRGTI-DEAGA 67
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
+ + + D+A A A+ + E + E +++K +F+ L V I
Sbjct: 68 AAIAERIGWSTDVADAAPAALAI-EAIVERMDVKTGLFETLARHVAPGAILASNTSSLSI 126
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+ + H NP + LVE++P+ T P V A+M + PV + R
Sbjct: 127 EAMASAVPGPERFAGLHFFNPVPAMKLVELIPSSRTAPTVVDDLEALMRAWKKLPVRV-R 185
Query: 596 EIDGFVLNRI 625
++ GF++NR+
Sbjct: 186 DVPGFIVNRV 195
>UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=5; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacter sphaeroides ATCC 17025
Length = 673
Score = 58.0 bits (134), Expect = 2e-07
Identities = 46/191 (24%), Positives = 80/191 (41%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
++G++G G +G A A+ G + TL + + I ++ + G L
Sbjct: 292 RIGVIGGGTMGSGIAAAIAAAGLEATLAETGPDALEAGIKRVRAIFEAQVTRG-LTDRAG 350
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
A ++ V GT L + D V E V E+L +K++VF++L + + I
Sbjct: 351 AADRLARVSGTVGLG-PLADCDLVIEAVFEDLAVKRRVFEDLTRLCRPDAILATNTSYLD 409
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ + + I H +P + L+EIVP T A+ +G+ PV
Sbjct: 410 PERIVAGLPNPDRFIALHFFSPAQVMKLLEIVPLVATTSRTLATGFALAARLGKIPVQAG 469
Query: 593 REIDGFVLNRI 625
+GF+ NRI
Sbjct: 470 NG-EGFIGNRI 479
>UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 304
Score = 57.6 bits (133), Expect = 2e-07
Identities = 48/195 (24%), Positives = 83/195 (42%), Gaps = 3/195 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+KV I+G+G +G+ L A+ G++ ++D+ + A K +L+ L + R L
Sbjct: 10 KKVLILGAGSMGQQIGFLCAAKGFETAIYDLSPPLLDTA----KKRLEKLAGRFVSRHRL 65
Query: 230 NADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
+E V T D A +A F+ E V E++E+K +VF+ + I
Sbjct: 66 TGEEAAAAMARVTLTPDSEQAAANADFISESVTESVEIKCRVFETFHPLCPARAIFTTNT 125
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
+ + H N +V+I+P P T PE + RA +GQ P
Sbjct: 126 SSLIPSMLTHAVGRPDRFAAFHFHNT-LTSDIVDIMPHPGTTPETAETIRAFALRLGQVP 184
Query: 581 VTLSREIDGFVLNRI 625
+ +E G+ N +
Sbjct: 185 IVFKKENHGYAFNAL 199
>UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified
Gammaproteobacteria (miscellaneous)|Rep: Enoyl-CoA
hydratase - marine gamma proteobacterium HTCC2080
Length = 699
Score = 57.6 bits (133), Expect = 2e-07
Identities = 50/190 (26%), Positives = 78/190 (41%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VGI+G+G +G AM FA G VTL D+ ++ + + I K G L +
Sbjct: 296 VGIIGAGTMGGGIAMCFAQAGIAVTLVDMTDEAVKGGLEKIAKNYAISVKKGRL--TVAQ 353
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
+ T + + V E V ENLE+KK+VF LD + +
Sbjct: 354 TDAILANITTSSSFDDLANVDMVIEAVFENLEVKKEVFGKLDVICKPGAVLASNTSYQSI 413
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
V+ H +P + L+E+V + V A+ ++IG+ V LS
Sbjct: 414 DAIAAATSRPESVLGMHFFSPANVMKLLEVVKGASSSDIVIATAMAVGKKIGKVSV-LSG 472
Query: 596 EIDGFVLNRI 625
GF+ NR+
Sbjct: 473 MCYGFIGNRM 482
>UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=32;
Proteobacteria|Rep: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE -
Brucella melitensis
Length = 565
Score = 56.8 bits (131), Expect = 4e-07
Identities = 43/190 (22%), Positives = 80/190 (42%), Gaps = 2/190 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+ IVG+G++G A + A G +FD E ++ + L L + +G ++A
Sbjct: 48 IAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASLDRLASTLAKLAE----KGKISA 103
Query: 236 DEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
++ V C + D V E + E L+ K+ +F L+ VV N I
Sbjct: 104 EDAQTAVSRIEICSSIQELADCDLVVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSL 163
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+H +V H NP + +VE++ T P V + + +G +
Sbjct: 164 SVTSIARVCRHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAVGDALLVLAKRMGHHGIR- 222
Query: 590 SREIDGFVLN 619
++++ GF++N
Sbjct: 223 AKDMPGFIIN 232
>UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 710
Score = 56.8 bits (131), Expect = 4e-07
Identities = 50/198 (25%), Positives = 82/198 (41%)
Frame = +2
Query: 32 ASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG 211
AS E++G+VG G +G A+ G VT+ + E + A ++ L G
Sbjct: 299 ASARPVERIGVVGGGTMGAGIAVSALDAGLPVTMIERDEASLARGRAHVEKVYDGLVAKG 358
Query: 212 LLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 391
+ +A + GT A+A D + E V E++ +KK VF L V +
Sbjct: 359 RMTPAAHAARLARFKGGTSYDALAQADVVI--EAVFEDMAVKKAVFAELARVCKPGAVLA 416
Query: 392 XXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIG 571
++ A VI H +P + L+EIV +V A+ +++
Sbjct: 417 TNTSYLDIDELAASIDRPADVIGLHFFSPANVMKLLEIVVPARVSADVVATAFALAKQLK 476
Query: 572 QEPVTLSREIDGFVLNRI 625
+ PV + DGF+ NRI
Sbjct: 477 KTPVR-AGVCDGFIGNRI 493
>UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Salinibacter ruber (strain DSM 13855)
Length = 719
Score = 56.8 bits (131), Expect = 4e-07
Identities = 44/161 (27%), Positives = 71/161 (44%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ VG++G+GL+G A + A G V L D + I + E G++
Sbjct: 319 DTVGVLGAGLMGSGIAQVSAQNGLDVVLTDQSLALAAEGKKAIWSAVTEQEDKGIIN-TF 377
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
D+ + V T D A ++ A V E VPE+L +K V ++ VVD +T+
Sbjct: 378 TRDQIVERVAPTADYA-PLQAADVVIEAVPEDLSIKHAVLSEVETVVDADTVLASNTSAL 436
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 532
E + ++V+ H +P +PL+EIV T E
Sbjct: 437 PISTIAEGVDDPSRVLGMHYFSPVPDIPLLEIVVTEETSDE 477
>UniRef50_A2QA05 Cluster: Catalytic activity:; n=4;
Trichocomaceae|Rep: Catalytic activity: - Aspergillus
niger
Length = 622
Score = 56.8 bits (131), Expect = 4e-07
Identities = 52/214 (24%), Positives = 88/214 (41%), Gaps = 2/214 (0%)
Frame = +2
Query: 14 TLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK 193
T + KS + I+G+G++GR A +F+S GY V + D + A I +
Sbjct: 3 TTNTTITHPSKSRPIVIIGAGILGRRIAAVFSSAGYSVHISDPSPSALDSARTYISTHIH 62
Query: 194 TLEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVD 373
+ R +L+ + + AV A + E VPE L +K+ +F +L
Sbjct: 63 EFTTH-IPRPSLSPGP----ISTFTSVPEAVATAWLIVEAVPEILPIKQSLFADLHAHSP 117
Query: 374 DNTIXXXXXXXXXXXXXXENMKHKAQVIV--SHPVNPPYYVPLVEIVPAPWTKPEVTKKT 547
+ I ++ +V++ H PP + VE++ T V
Sbjct: 118 ADCILASNSSSYKSRLIGGHLPLPRRVLLLNMHFTMPP-AIRTVELMTCGDTHERVFPML 176
Query: 548 RAIMEEIGQEPVTLSREIDGFVLNRIQYAILGEV 649
++ E G PVT +E GF+ NR+ AI E+
Sbjct: 177 SGVLSECGVIPVTARKESTGFIFNRLWAAIKREI 210
>UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 293
Score = 56.4 bits (130), Expect = 6e-07
Identities = 43/192 (22%), Positives = 85/192 (44%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ VG++G GL+G A A+ G+ V + + ++ + ++ L + G + +
Sbjct: 4 KSVGVIGCGLMGSGIAQAAATAGFPVIVLEAEQRFLDRGFTGVERSLAKFAEKGTITESP 63
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+A +KGT ++ + D + E + EN+ K K++ L+ V + I
Sbjct: 64 DAIRAR--LKGTTNVE-DLADCDIIIEAILENVPEKHKMYAALEKVAKPDAIFASNTSSI 120
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
K + I H NP + LVE++ T EV + ++G+ PV
Sbjct: 121 SITELMAATKRPERFIGLHFFNPVPLMKLVEVIRTIATSDEVFEAAVDFGTKLGKVPVR- 179
Query: 590 SREIDGFVLNRI 625
+++ GF++NR+
Sbjct: 180 TKDSSGFIVNRL 191
>UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 304
Score = 56.0 bits (129), Expect = 7e-07
Identities = 47/189 (24%), Positives = 77/189 (40%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+V +VG G +GR A A+ GY VT++D+ + + I L +G ++
Sbjct: 8 QVLVVGGGTMGRQIAFQCAAHGYFVTIYDISAEVLQATQKRIGAYADYLVAEGHIQPQA- 66
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
A + + D A +A + E VPE+ LK +VF D TI
Sbjct: 67 AKRAINRISISTD-ARQAANADLLCEAVPEDPALKGEVFARFDRYCPQRTIFSTNASLLV 125
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ + + H P + L +++P T EV K + I Q P+ L+
Sbjct: 126 PSQIAKATGRPDRFLALHFHQPVWVGNLADVMPHAGTSSEVVKVVHDFAKSINQIPLVLN 185
Query: 593 REIDGFVLN 619
+E G+V N
Sbjct: 186 KENFGYVFN 194
>UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 801
Score = 55.6 bits (128), Expect = 1e-06
Identities = 49/204 (24%), Positives = 87/204 (42%), Gaps = 10/204 (4%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEK---DGL 214
K +K ++GSG++G A L AS G + L D+V +TD + K D +
Sbjct: 4 KIKKAAVIGSGVMGGGIAALLASAGVETLLLDIVPFDLTDEQKKDPAARNRIVKFGYDTI 63
Query: 215 LRGNLNA-----DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDN 379
+ A D + D + D ++ E V ENL++K+++F+ ++ V
Sbjct: 64 MMSRPAALMHSSDAALISIGNLEDDFDKLADCDWIVEVVVENLKIKQQLFKRIEPVRKKG 123
Query: 380 TIXXXXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRA 553
+I E + K + +H NP Y+ L+EI+ T EV + A
Sbjct: 124 SIISSNTSGIPLKAMSEGLSSDFKQHFLGTHFFNPVRYMHLLEIIKGEETSEEVLRFMAA 183
Query: 554 IMEEIGQEPVTLSREIDGFVLNRI 625
E+ + + +++ F+ NRI
Sbjct: 184 FGEKRLGKGIVWAKDTPNFIGNRI 207
>UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Shewanella woodyi ATCC 51908|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Shewanella woodyi ATCC 51908
Length = 696
Score = 55.6 bits (128), Expect = 1e-06
Identities = 50/205 (24%), Positives = 89/205 (43%)
Frame = +2
Query: 11 QTLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL 190
Q L +S VG+VG+G +G A F G + + E+ + + +++
Sbjct: 293 QKLATSTSSTRTINTVGVVGAGNMGVGIARCFIDAGMDLIWIEQTEEALLRGMDNLRKGY 352
Query: 191 KTLEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVV 370
++ G + + D++ Q VKG+ + + V E E+LE+KK +F+ LD
Sbjct: 353 QSKITKGHMTEQ-DLDDKMQLVKGST-VYDRLAPCDLVVEAAFEDLEVKKIIFKALDQHC 410
Query: 371 DDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 550
D+ I + QV+ H +P + + L+EIV A T +V K
Sbjct: 411 KDSAILATNTSYLDINSIAKVTSRPDQVVGLHFFSPAHVMKLIEIVRAENTADDVIKTML 470
Query: 551 AIMEEIGQEPVTLSREIDGFVLNRI 625
A+ ++ + PV + GF NR+
Sbjct: 471 ALGVKLRKYPVEVG-VCFGFAANRM 494
>UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=16;
Gammaproteobacteria|Rep: Fatty acid oxidation complex
subunit alpha [Includes: Enoyl-CoA
hydratase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 731
Score = 55.6 bits (128), Expect = 1e-06
Identities = 50/199 (25%), Positives = 84/199 (42%), Gaps = 1/199 (0%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGY-QVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+VGI+G GL+G A + A+ G V + D+ E+ I A+ QL T
Sbjct: 324 RVGILGGGLMGGGIASVTATRGQLPVRIKDINEQGINHALK-YNWQLLTKRVQSKRMKPT 382
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ G+ D + A V E V E+L LK+++ +++ +TI
Sbjct: 383 ERQRLMTLISGSTDYR-GFEHADIVIEAVFEDLALKRQMITEIEDHAAPHTIFASNTSSL 441
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
E + V+ H +P +PLVE++P T E T A+ + G+ + +
Sbjct: 442 PIHQIAEGARRPQLVVGLHYFSPVDKMPLVEVIPHAHTSAETVATTVALARKQGKTAIVV 501
Query: 590 SREIDGFVLNRIQYAILGE 646
+ GF +NRI + E
Sbjct: 502 G-DSAGFYVNRILAPYINE 519
>UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2;
Bordetella|Rep: Putative enoyl-CoA isomerase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 694
Score = 55.2 bits (127), Expect = 1e-06
Identities = 45/197 (22%), Positives = 82/197 (41%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
E+V +VG+G +G + A G V DV ++ A + + L L
Sbjct: 288 EQVAVVGAGTMGTGIVICLADAGLPVIWHDVDADRLAQGRAQVCQHFERLAARKRLTSR- 346
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A+++ V T ++A + A E V E++ +K VF+ LD V+ I
Sbjct: 347 QAEQRVAAVATTGEMA-GIAQADLAIEAVFEDMAVKCAVFRELDRVLKPGAILGTNTSTL 405
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ + V+ H +P +PL+EIV T +V + + + ++ +
Sbjct: 406 DVDRIAHSTRRPQDVVGLHFFSPAPVMPLLEIVRGAATHADVVAAAQGLARRL-RKTAVV 464
Query: 590 SREIDGFVLNRIQYAIL 640
+ DGF+ NR+ + L
Sbjct: 465 AGVCDGFIGNRMWHQYL 481
>UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 284
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/193 (26%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ VG+VG G +G A +FA++G V + + +++ A+ + L + G L G++
Sbjct: 7 KNVGVVGGGRMGAGIAQVFATLGSTVIIAESGDREA--AVKRVSDGLDRAHERGKL-GDV 63
Query: 230 NADEQFQCVKGTCDLAIAVKDAI-FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
+ V T A+ A+ V E VPE ++LK V ++ V T+
Sbjct: 64 DPATILGRVS-TVAAPDALPPALDLVVEAVPELVDLKLSVLSLVEKTVSPTTVIASNTSS 122
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+ A++I H NP LVEIV AP T V +K R + ++G+ V
Sbjct: 123 ISIAELGSALGDPARLIGMHFFNPVPASSLVEIVRAPATDAGVVEKVREWVAQLGKTEV- 181
Query: 587 LSREIDGFVLNRI 625
L + GF +R+
Sbjct: 182 LVNDSPGFATSRL 194
>UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 310
Score = 55.2 bits (127), Expect = 1e-06
Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 1/170 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V ++G+GL+G A A G +V L+D Q + ++ +Q +K+ L R + A
Sbjct: 8 VAVIGAGLMGTCIAGELAYHGARVNLYDR-SAQAMEKSKEMLIQ----QKEQLKREEVMA 62
Query: 236 DEQFQCVKGTCD-LAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
F C+ L AV ++ + E ENLE+KK VF+++ N +
Sbjct: 63 TSDFIGTVAFCESLEEAVVNSGLIFEATIENLEVKKSVFKSISQFCRTNAVIATNTLALD 122
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIME 562
E++ + + + + P Y +P VEI T PE +K + +E
Sbjct: 123 TSVVAEHVTNPERCLGIRFLYPVYSIPEVEITLGSQTSPETIQKVQQFLE 172
>UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=10; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 509
Score = 54.8 bits (126), Expect = 2e-06
Identities = 44/190 (23%), Positives = 80/190 (42%), Gaps = 2/190 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
+ IVG+G++G A + A G +FD E A A + +L + +G ++A
Sbjct: 8 IAIVGAGVMGTGIAQIAAQAGLVTQIFDARE----GAAAASRDRLASTLAKLAEKGKISA 63
Query: 236 DEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
++ V C + D V E + E L+ K+ +F L+ VV N I
Sbjct: 64 EDAQTAVSRIEICSSIQELADCDLVVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSL 123
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+H +V H NP + +VE++ T P V + + +G +
Sbjct: 124 SVTSIARVCRHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAVGDALLVLAKRMGHHGIR- 182
Query: 590 SREIDGFVLN 619
++++ GF++N
Sbjct: 183 AKDMPGFIIN 192
>UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 281
Score = 54.8 bits (126), Expect = 2e-06
Identities = 56/201 (27%), Positives = 90/201 (44%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
KV ++G+GL+GR A+ AS ++V L DV EK + A I +L L K
Sbjct: 2 KVFVIGAGLMGRGIAIAIAS-KHEVVLQDVSEKALEAAREQIPEEL--LSK--------- 49
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
++ T L VKD V E V E+L K +V + ++ + N
Sbjct: 50 -------IEFTTTLE-KVKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSVIS 99
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
E + ++ + H +NPP+ +PLVEIV + +T + + E+G+E V
Sbjct: 100 VDDIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVVVCK 159
Query: 593 REIDGFVLNRIQYAILGEVWR 655
+ ++NR A+L E R
Sbjct: 160 GQ---SLVNRFNAAVLSEASR 177
>UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=92;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bradyrhizobium japonicum
Length = 293
Score = 54.8 bits (126), Expect = 2e-06
Identities = 48/201 (23%), Positives = 85/201 (42%), Gaps = 2/201 (0%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL--KTLEKDGLLRG 223
+KVG++G+G +G A + A G+ V L DV ++ +A I L + +K
Sbjct: 6 KKVGVIGAGQMGNGIAHVAALAGFDVVLNDVSADRLKSGMATINGNLARQVSKKVVTEEA 65
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
A + + DLA D V E E E+K+K+F L V+ I
Sbjct: 66 KTKALSRIVAAEKLDDLA----DCDLVIETAVEKEEVKRKIFHELCAVLKPEAIVASDTS 121
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ I H +NP + LVE++ T + ++ + ++G++ V
Sbjct: 122 SISITRLAAATDRPERFIGIHFMNPVPLMELVELIRGIATDDATFEASKEFVAKLGKQ-V 180
Query: 584 TLSREIDGFVLNRIQYAILGE 646
+S + F++NRI ++ E
Sbjct: 181 AVSEDFPAFIVNRILLPMINE 201
>UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=116; cellular
organisms|Rep: Fatty acid oxidation complex subunit
alpha [Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Yersinia pestis
Length = 729
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/197 (22%), Positives = 89/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQI----TDAIADIKVQLKTLEKDGLLRGNL 229
++G+G++G A A V + D+ E + +A + QL+ + DGL ++
Sbjct: 318 VLGAGIMGGGIAYQSALKSVPVIMKDINENSLDLGMNEAAKLLNKQLERGKVDGLKMASI 377
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A ++ T D A ++ A + E V EN ++K V ++ ++ ++T+
Sbjct: 378 LAT-----IRPTLDYA-GIERAQVIVEAVVENPKVKAAVLAEVEALIGEDTVLASNTSTI 431
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+++K H NP + +PLVEI+ T + A ++G+ P+ +
Sbjct: 432 PIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGAKTSDKTLAAVVAYATQMGKTPIVV 491
Query: 590 SREIDGFVLNRIQYAIL 640
+ + GF +NR+ + L
Sbjct: 492 N-DCPGFFVNRVLFPYL 507
>UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Pseudoalteromonas haloplanktis (strain TAC 125)
Length = 281
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/201 (22%), Positives = 89/201 (44%), Gaps = 3/201 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+V I+GSG + + + +V+ +++ + A+A K + + L R
Sbjct: 2 EVSIIGSGTMATGITQVLC-LSNEVSKVNLIARTEEKALASKSTCAKNISR--LARKGKI 58
Query: 233 ADEQ--FQCVKGTCDLA-IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+DEQ F K C+ +AV ++ + E + E+ K +F L ++D+ I
Sbjct: 59 SDEQASFALEKLYCNAELVAVVNSDLIIEAIVEDFTAKMVLFSKLAEFINDSVIVASNTS 118
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ + V+ H NP + LVEI+ T P + + + + +G+ PV
Sbjct: 119 SLSITAFASVLPNPQNVVGLHFFNPAPIMELVEIIVGHETAPAKIQLLQGLTKNLGKVPV 178
Query: 584 TLSREIDGFVLNRIQYAILGE 646
+ +E GFV+NR+ ++ E
Sbjct: 179 VV-QEAPGFVVNRMLIPMINE 198
>UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=104; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 736
Score = 54.0 bits (124), Expect = 3e-06
Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 8/203 (3%)
Frame = +2
Query: 41 FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDV-VE-----KQITDAIAD--IKVQLKT 196
+++ KVG++G+G++G A A G +V L DV VE K ++ + D I T
Sbjct: 322 YRAVKVGVLGAGMMGAGIAYSCARSGMEVVLKDVAVESAEKGKAYSEKLLDKAIAKGRST 381
Query: 197 LEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDD 376
EK L G + A + G CDL I +A+F E+ LK++VF + VD
Sbjct: 382 EEKKAELLGRITATADAADLAG-CDLVI---EAVF------EDPSLKQQVFAEIAPYVDQ 431
Query: 377 NTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAI 556
+ + + A I H +P +PLVEI+ T K +
Sbjct: 432 DALLCSNTSTLPITELASGVDRPADFIGLHFFSPVDKMPLVEIIRGAKTSDVALAKAYDV 491
Query: 557 MEEIGQEPVTLSREIDGFVLNRI 625
+++I + P+ ++ + GF +R+
Sbjct: 492 VQQIRKTPIVVN-DSRGFYTSRV 513
>UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=9; Actinomycetales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Arthrobacter sp. (strain FB24)
Length = 290
Score = 54.0 bits (124), Expect = 3e-06
Identities = 51/201 (25%), Positives = 83/201 (41%), Gaps = 1/201 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK-VQLKTLEKDGLLRGNLN 232
VG++G G +G A F G V + + E A ++ K++E+ G GNL
Sbjct: 14 VGVLGGGRMGAGIAHAFLINGANVLVVERDEASAEAARERVESAAAKSIER-GATDGNL- 71
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
DE + T D KD V E VPE+ ELK + ++ + D+
Sbjct: 72 -DEMVSRLSVTVDYD-DFKDRELVVEAVPEDWELKVASLREIEARLSDDAYLASNTSSLS 129
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+K + H NP L+E+V T P++ + +E +G+ V ++
Sbjct: 130 VNGLARELKRPGNFLGLHFFNPVPASTLIEVVLGEQTSPDLAAAAKRWVEALGKTAVVVN 189
Query: 593 REIDGFVLNRIQYAILGEVWR 655
+ GF +R+ AI E R
Sbjct: 190 -DAPGFASSRLGVAIALEAMR 209
>UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius sp.
HTCC2601|Rep: Enoyl-CoA hydratase - Roseovarius sp.
HTCC2601
Length = 634
Score = 53.2 bits (122), Expect = 5e-06
Identities = 52/199 (26%), Positives = 76/199 (38%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+ +VG+ G AM FA G V L D QI A A I G + G
Sbjct: 293 RAAVVGADSAGAGIAMCFARAGLPVVLIDTDAAQIERARARIAELWDQARDGGGIDGPTL 352
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
++ + T A A D + V E++ +++F LD + I
Sbjct: 353 VAQRARLELSTELHAAASADVVVA--AVSEDMTQTQEIFSALDRICKPGAILVNNGATLD 410
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ + VI H + P V L+E+V T PEV A+ + ++PV L
Sbjct: 411 LDSIAQATRRPGDVIGMHFLQPDGAVRLLEVVRGARTAPEVIATVMALAPRLDKQPV-LV 469
Query: 593 REIDGFVLNRIQYAILGEV 649
DG V NR+ A EV
Sbjct: 470 GVCDGLVGNRMVRAFGREV 488
>UniRef50_A3T2M8 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=4; cellular organisms|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Sulfitobacter sp. NAS-14.1
Length = 695
Score = 53.2 bits (122), Expect = 5e-06
Identities = 53/199 (26%), Positives = 84/199 (42%), Gaps = 6/199 (3%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
+E +VG G +G + A A+ G VT VVE+ + A K L+ L G+ RG
Sbjct: 286 AETAIVVGGGNMGAAIAYTLATAGISVT---VVERSASSAEWASK-NLQKLIDQGISRGI 341
Query: 227 LNADEQFQCVKGTCDLAIAVK--DAI----FVQECVPENLELKKKVFQNLDNVVDDNTIX 388
L+ D K D + V DA+ E E+ +K + L+ + TI
Sbjct: 342 LSVD----AAKTVEDRLVTVSGYDALPPTDLAIEAAFEDFAVKTAILTELEGALPPETII 397
Query: 389 XXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEI 568
+ +KH A+ + H +P + + L+E+V + T + +
Sbjct: 398 ATNTSYLDVNRLSDGLKHPARFVGMHFFSPAHIMKLLEVVRSDRTSDGTLGAALVLAHRL 457
Query: 569 GQEPVTLSREIDGFVLNRI 625
G+ PV LS DGF+ NRI
Sbjct: 458 GKIPV-LSGVCDGFIGNRI 475
>UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=5; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Xanthobacter sp. (strain Py2)
Length = 789
Score = 52.8 bits (121), Expect = 7e-06
Identities = 48/200 (24%), Positives = 91/200 (45%), Gaps = 5/200 (2%)
Frame = +2
Query: 41 FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITD--AIADIKVQLKTLEKDGL 214
F +KV ++G+G++G A A+ G +V L D+V + + AIA+ V+ K L+ D
Sbjct: 16 FDIKKVAVIGAGVMGAGIAAHVANAGIEVLLLDIVPEGAANRNAIAEKAVE-KLLKADPA 74
Query: 215 LRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 394
+ A + +L+ + ++ E V E L++K+ ++ ++ +
Sbjct: 75 AFMSKRAAKLVTAGNIEDNLS-DLASCDWIVEAVIERLDIKQALYAKIEAARRPGSAVSS 133
Query: 395 XXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKP-EVTKKTRAIMEE 565
+ + +++H NPP Y+ L+EIV P T P V R +
Sbjct: 134 NTSTIPLGDLTAGLPESFRRDFLITHFFNPPRYMRLLEIVAGPETNPATVAAVARFADVK 193
Query: 566 IGQEPVTLSREIDGFVLNRI 625
+G+ VT ++ GF+ NR+
Sbjct: 194 LGKTVVT-CKDTPGFIANRL 212
>UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2;
Sinorhizobium|Rep: 3-hydroxybutyryl-CoA epimerase -
Sinorhizobium medicae WSM419
Length = 442
Score = 52.8 bits (121), Expect = 7e-06
Identities = 45/198 (22%), Positives = 82/198 (41%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
++G G +G A + G + + + E A+A ++ K + L A E
Sbjct: 49 VIGGGTMGTGIAAALCNAGLPLVIVERDEAAREGAVARLRAIFDGAVKRRRISAGLAA-E 107
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
+ V G D A+ + +A + E V E+L++K+ VF+ + + +
Sbjct: 108 RLARVTGATDYAV-LAEADLIIEAVFEDLDVKRDVFRKVAAACRHDAVLATNTSYLNPER 166
Query: 422 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREI 601
+ + + + H +P + L+EIVP T PE A+ + + PV
Sbjct: 167 IADGIASPERFLGLHFFSPAQVMKLLEIVPTGATAPEALATGFALARMLNKIPVRAGIS- 225
Query: 602 DGFVLNRIQYAILGEVWR 655
DGF+ NRI + G+ R
Sbjct: 226 DGFIGNRILKVMRGQAER 243
>UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 733
Score = 52.8 bits (121), Expect = 7e-06
Identities = 47/189 (24%), Positives = 82/189 (43%), Gaps = 8/189 (4%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT----LEKDG-- 211
E+V I+G+G++G A + A GYQV L D+ ++ + +A + QL+ L+ G
Sbjct: 333 ERVAILGAGMMGAGLAYICADAGYQVVLKDINQEALDKGVAHFEAQLRKRKRHLDDAGRQ 392
Query: 212 LLRGNLNADEQFQCV--KGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 385
+R L + + G DL I +A+F ENL+LK +V + + + + I
Sbjct: 393 AIRDRLTPSLELSALSDNGGTDLII---EAVF------ENLDLKHRVTRETEPTLSADGI 443
Query: 386 XXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEE 565
+ H + I H +P +PL+EIV P T +
Sbjct: 444 WASNTSAIPIGDLAKVSAHADRFIGLHYFSPVEVMPLLEIVVGPETSERTLARCLDFCRR 503
Query: 566 IGQEPVTLS 592
I + P+ ++
Sbjct: 504 IKKLPIVVN 512
>UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
related protein; n=3; Thermoplasmatales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase related protein -
Thermoplasma acidophilum
Length = 314
Score = 52.8 bits (121), Expect = 7e-06
Identities = 29/113 (25%), Positives = 57/113 (50%), Gaps = 5/113 (4%)
Frame = +2
Query: 302 VQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPP 481
V E EN ++K ++F ++ ++ ++ I +K ++ H NPP
Sbjct: 115 VIEAAFENQDVKNRIFSDISDL-SEHAIIASNTSSLSITEMSSRLKRPENALILHFFNPP 173
Query: 482 YYVPLVEIVPAPWTKPEVTKKTRAIMEEI-----GQEPVTLSREIDGFVLNRI 625
Y +PLVE+VP+ +T E +++ + G PV +++E +GF++NR+
Sbjct: 174 YLLPLVEVVPSLYTSDEAKNTAVSLISRMKNHREGMVPV-MAKEREGFIVNRL 225
>UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=6; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Roseiflexus sp. RS-1
Length = 807
Score = 52.4 bits (120), Expect = 9e-06
Identities = 52/209 (24%), Positives = 91/209 (43%), Gaps = 17/209 (8%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLE-KDGLLRGN 226
+KV ++G+G +G A + G QV L D V +T + L++ E ++ +R
Sbjct: 5 KKVAVIGAGTMGGGIAAHCINAGLQVVLLDTVPSSLTPEEEKRGLTLESKEVRNRFVRAG 64
Query: 227 L----NA------DEQF--QCVKGTC--DLAIAVKDAIFVQECVPENLELKKKVFQNLDN 364
L NA D Q + V G DLA+ + DA ++ E + E LE K+ + + ++
Sbjct: 65 LERIKNARPAALFDPQSISRIVTGNVEDDLAL-IADADWIVEAIIEQLEPKRALMEKIEQ 123
Query: 365 VVDDNTIXXXXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVT 538
V +I + + +H NPP Y+ L+E++P P T P+V
Sbjct: 124 VRKPGSIVSSNTSGIPIAAIAAGRSDDFRRHFLGTHFFNPPRYLYLLEVIPTPDTDPQVV 183
Query: 539 KKTRAIMEEIGQEPVTLSREIDGFVLNRI 625
+ + V + ++ F+ NRI
Sbjct: 184 AAISRFADVTLGKGVVICKDRPNFIGNRI 212
>UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep:
Blr2428 protein - Bradyrhizobium japonicum
Length = 715
Score = 51.6 bits (118), Expect = 2e-05
Identities = 48/190 (25%), Positives = 84/190 (44%), Gaps = 1/190 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDGLLRGNLN 232
V ++G+G +G A A G +V+L D+ + I A+ ++ K + K +R L
Sbjct: 343 VHVIGAGAMGGDIAAWCAGQGLRVSLADMKAEPIAGAVKRAAELYGKIIRKPTEVRDAL- 401
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
D + G V++A V E VPE LELK+KV+ L+ + I
Sbjct: 402 -DRLIPDMDGE-----GVRNADLVIEAVPEKLELKQKVYAGLEPKMKPGAILATNTSSIP 455
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ +++ H NP + LVE+V +V ++ A + I + P+ +
Sbjct: 456 LQDLRTTLARPDRLVGLHFFNPVSRLQLVEVVSHDGNDAQVLREALAFVGAIDRLPLAV- 514
Query: 593 REIDGFVLNR 622
+ GF++NR
Sbjct: 515 KSSPGFLVNR 524
>UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=20; Proteobacteria|Rep:
Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 797
Score = 51.6 bits (118), Expect = 2e-05
Identities = 48/201 (23%), Positives = 84/201 (41%), Gaps = 4/201 (1%)
Frame = +2
Query: 35 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQ-ITDAIADIKVQLKTLEKDG 211
SK KV ++G+G++G A A+ V LFD+ K + + D + T
Sbjct: 2 SKLIIRKVAVLGAGVMGAQIAAHCANADVPVVLFDLPAKDGPPNRVVDRAIGGLTKLDPA 61
Query: 212 LLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 391
L + A DL ++D V E + E LE K+ ++ + + I
Sbjct: 62 PLAAAVRASH-IDAANYDSDLE-RLRDCDLVIEAIAEKLEWKRDLYAKAAPYLRPDAIFA 119
Query: 392 XXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRA-IME 562
E + +++ H NPP Y+ LVE++PAP T P + A ++
Sbjct: 120 SNTSGLSIATLAEGLPEALRSRFCGVHFFNPPRYMALVELIPAPATDPLMLDALEAWLVT 179
Query: 563 EIGQEPVTLSREIDGFVLNRI 625
+G+ + +++ FV NR+
Sbjct: 180 RLGKS-IVRAKDTPNFVANRV 199
>UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA
dehydrogenase,possibly related to diterpenoid
metabolism; n=6; Proteobacteria|Rep: DitN-like
3-hydroxyacyl-CoA dehydrogenase,possibly related to
diterpenoid metabolism - Azoarcus sp. (strain EbN1)
(Aromatoleum aromaticum (strain EbN1))
Length = 299
Score = 51.6 bits (118), Expect = 2e-05
Identities = 42/198 (21%), Positives = 80/198 (40%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
EK+ +VG+GL+G A A GY++ L D + A+ I + K G L
Sbjct: 5 EKIIVVGAGLMGTGIAYSCAISGYRILLVDANPSALDKAVGQINSLVAAGVKLGKL-VEA 63
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
+ ++ +L DA + E E +++K + D ++ I
Sbjct: 64 AGKAALERLEAAIELDGRASDAALLIETATEKIDIKLAIIGKADELLPPEAIIASNTSAL 123
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ Q H NP + + LVE++ T ++ +A+ +G+ + +
Sbjct: 124 SISELAAATRRPTQFAGMHFFNPVHKMKLVELIRGIETTQATVERLKAVTAALGKTSIVV 183
Query: 590 SREIDGFVLNRIQYAILG 643
+ E GF +R+ A++G
Sbjct: 184 N-EAPGFTTSRMS-ALMG 199
>UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Acidobacteria bacterium
Ellin345|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Acidobacteria bacterium (strain
Ellin345)
Length = 806
Score = 51.6 bits (118), Expect = 2e-05
Identities = 47/197 (23%), Positives = 84/197 (42%), Gaps = 5/197 (2%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLE--KDGLLRG 223
EKV ++G+G +G A FA+ G LFD+V D A K+ L+ K
Sbjct: 6 EKVAVLGAGTMGARIAAHFANAGIPSYLFDIVPPD-ADGPARNKIAAAGLDAAKKSKPAA 64
Query: 224 NLNAD-EQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
+ D + V D + + ++ E V ENLELK+ + + ++ V ++
Sbjct: 65 FFHPDLAKLVTVGNFEDDLKKLGECDWIIEAVVENLELKRALLKKVEAVRKPGSLITTNT 124
Query: 401 XXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQ 574
E + +H NPP Y+ L+E++P P T P+ + + +
Sbjct: 125 SGLPVSKISEGFSEDFRRNWFGTHFFNPPRYMRLLELIPTPDTDPKAMEAVAHLGDVQLG 184
Query: 575 EPVTLSREIDGFVLNRI 625
+ + +++ F+ NRI
Sbjct: 185 KGIVHAKDTPNFIGNRI 201
>UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Mesorhizobium sp. (strain BNC1)
Length = 677
Score = 51.6 bits (118), Expect = 2e-05
Identities = 47/194 (24%), Positives = 83/194 (42%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
++G++G+G +G A+ + G V L D + +T A A +K L LE+ G L+
Sbjct: 287 RLGVIGAGTMGVGLAVSLLAAGKSVVLIDKDDLALTRASAAVKSGLARLERGGKLKE--A 344
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
D + + +L+ AV++ V E V E+ E+K V +L + +
Sbjct: 345 PDAALARLVASKELS-AVENCEVVIEAVVESFEVKSAVLSDLHARLSPGAMVVSNTSYLD 403
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+ + H P + LVE+VP P T ++ ++G+ V +
Sbjct: 404 IAELARASGRPDRFLGLHFFAPVPVMTLVEVVPLPETSSHTLTVATQLVRDMGKVAVR-A 462
Query: 593 REIDGFVLNRIQYA 634
+GF+ NRI A
Sbjct: 463 GPCNGFLGNRIYAA 476
>UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13;
cellular organisms|Rep: 3-hydroxybutyryl-CoA epimerase -
Pseudomonas putida W619
Length = 423
Score = 51.6 bits (118), Expect = 2e-05
Identities = 45/208 (21%), Positives = 89/208 (42%), Gaps = 2/208 (0%)
Frame = +2
Query: 29 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 208
+++ + ++ ++G+G +GR + A G V D + T+A + Q +
Sbjct: 12 VSTSYNVQQTAVIGAGTMGRGIVISLARAGLPVLWLDN-DPSATEAGLAMLAQTWAQQVG 70
Query: 209 GLLRGNLNADEQFQCVKGTCDLAIAVK--DAIFVQECVPENLELKKKVFQNLDNVVDDNT 382
+G ++ + C+ + + +A V E V ENL LK+++F+ LD+ +
Sbjct: 71 ---KGRIDQAQADACLARVRQVTAYTELAEADLVIEAVYENLALKQEIFRALDSTLKPEA 127
Query: 383 IXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIME 562
I QV+ H +P + + L+E+V T P V A+ +
Sbjct: 128 ILASNTSALDIDAIAAVTGRPEQVLGLHFFSPAHVMKLLEVVRGQLTAPAVLDAAVALGQ 187
Query: 563 EIGQEPVTLSREIDGFVLNRIQYAILGE 646
+G+E V ++ GF+ NR+ + E
Sbjct: 188 RMGKE-VVVAGNCPGFIGNRMLRTYVAE 214
>UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Paracoccus denitrificans PD1222|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 371
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/199 (23%), Positives = 83/199 (41%), Gaps = 2/199 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG-LLRGNLN 232
+ ++G G +G A +A+ G+ V D V + A+ ++ L + G L + +L+
Sbjct: 4 IAVIGLGTMGLGIAQTYAAAGFAVLATDAVPEARETALGRLRAGLAPRVRAGKLAQADLD 63
Query: 233 AD-EQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A + V G A+ D E V E + +K+ +F L+ VV + +
Sbjct: 64 AILARITVVDGP--KAMGATDLAI--EAVVERMPVKQSLFAALEAVVAPDAVLASNTSSL 119
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
E + +++ H NP + LVE+V P T + R + E G+ +
Sbjct: 120 SMAAMAEGLARPERLLGLHFFNPAPVMKLVELVAHPGTGAAALDRARRLTEAAGKTVIPC 179
Query: 590 SREIDGFVLNRIQYAILGE 646
+ GF++NR GE
Sbjct: 180 P-DRPGFIVNRCARPFYGE 197
>UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=95; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase (EC
4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase
(EC 1.1.1.35)] - Yersinia pseudotuberculosis
Length = 753
Score = 51.6 bits (118), Expect = 2e-05
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 1/202 (0%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+VG++G GL+G A + A+ G V + D+ + I A+ L + +R
Sbjct: 317 RVGVLGGGLMGGGIANVTATRAGLPVRIKDINPQGINQALKYTWDALGKRVRSKRMRPT- 375
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
Q + G+ D + V E V E+L LK+++ +++ +TI
Sbjct: 376 EQQRQMMLISGSTDYR-GFERVDIVVEAVFEDLSLKQQMVADIERFGAAHTIFASNTSSL 434
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ QVI H +P +PLVE++P T E T A+ + G+ + +
Sbjct: 435 PISQIAALAQRPEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIATTVALARKQGKTAIVV 494
Query: 590 SREIDGFVLNRIQYAILGEVWR 655
+ + GF +NRI + E R
Sbjct: 495 A-DRAGFYVNRILAPYINEAAR 515
>UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=42; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Salmonella typhimurium
Length = 729
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/195 (23%), Positives = 85/195 (43%), Gaps = 1/195 (0%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDGLLRGN 226
++ ++G+G++G A A G V + D+ +K + + + K+ K LE+ G + G
Sbjct: 314 KQAAVLGAGIMGGGIAYQSAWKGVPVIMKDINDKSLNLGMTEAAKLLNKQLER-GKIDG- 371
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
L + T D A + + V E V EN ++KK V + V T+
Sbjct: 372 LKLAGVISTIHPTLDYAGFDRVDVVV-EAVVENPKVKKAVLAETEQKVRPETVLASNTST 430
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
++ H NP + +PLVEI+ + E K A ++G+ P+
Sbjct: 431 IPIGELASALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIV 490
Query: 587 LSREIDGFVLNRIQY 631
++ + GF +NR+ +
Sbjct: 491 VN-DCPGFFVNRVLF 504
>UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;
n=3; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Nitrococcus mobilis Nb-231
Length = 726
Score = 51.2 bits (117), Expect = 2e-05
Identities = 51/201 (25%), Positives = 90/201 (44%), Gaps = 3/201 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 226
+VG++G+GL+G + + A+ V L DV K + + I ++ + L + + R
Sbjct: 331 RVGVLGAGLMGAGISFVTAARAKVPVRLKDVEPKGLASGLKYIDERIDQRLSRHAISRFE 390
Query: 227 LNADEQFQC-VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
E+ +C V T D + + V E V E+LELK ++ + ++ + + I
Sbjct: 391 A---ERARCRVTPTLDFS-GCRSLDLVIEAVFEDLELKHRMIREVEANCNADVIFASNTS 446
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ + VI H +P +PL+E++ T PEV A G+ P+
Sbjct: 447 SLPLARIAQAAERPQNVIGLHYFSPVDRMPLLEVIAHERTAPEVIATAMAFGRAQGKTPI 506
Query: 584 TLSREIDGFVLNRIQYAILGE 646
+ R+ GF +NRI L E
Sbjct: 507 VV-RDGVGFYVNRILAPYLNE 526
>UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 681
Score = 51.2 bits (117), Expect = 2e-05
Identities = 49/198 (24%), Positives = 83/198 (41%), Gaps = 2/198 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQLKTL-EKDGLLRGN 226
KVGIVG+GL+ A LF + V + D+ + + + + L EK L G
Sbjct: 318 KVGIVGAGLMASQLAQLFIERLEVPVVMKDISPEALEKGCGQVVEGFRRLGEKGKLTEG- 376
Query: 227 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
A V GT D D FV E V E + +KK+V L+ ++ + +
Sbjct: 377 -KARHLAGLVSGTLDFR-DFSDCDFVIEAVFEEMAVKKQVLGELEPLLRPDAVIATNTSS 434
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
++ +++ H NP +PLVE++ T E + ++ + V
Sbjct: 435 LSVTEMASVLRVPGRMLGFHFFNPVAVLPLVEVIRTAQTSGEALATAFDLARKLRKTGV- 493
Query: 587 LSREIDGFVLNRIQYAIL 640
L ++ F++NRI +L
Sbjct: 494 LVKDAPAFLVNRILVKML 511
>UniRef50_Q5P607 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=2; Proteobacteria|Rep: Fusion
of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 671
Score = 50.8 bits (116), Expect = 3e-05
Identities = 44/192 (22%), Positives = 83/192 (43%), Gaps = 2/192 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASV--GYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
V ++G+G IG S ++TL DV + + A+ G +
Sbjct: 21 VAVIGAGTIGPDIGYYLKSALPELKLTLVDVSQAALDRALQRFHDYAAKAVAKGKM-SEA 79
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
A + GT D + DA +V E EN+ LK+++F +++ VV + +
Sbjct: 80 EARAVTANLAGTLDYG-DIADADWVLEAATENIALKRRIFADVEAVVRPDALITSNTSSL 138
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
++H + V+H P + P+VE+V +P V + R + G+ P+ +
Sbjct: 139 PAAQIFAELRHPERATVTHFFAPAWRNPVVEVVRWEKAEPAVVEYLRWLFCSTGKVPL-V 197
Query: 590 SREIDGFVLNRI 625
+ ++ F+L+RI
Sbjct: 198 TDDVVCFMLDRI 209
>UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=7; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 723
Score = 50.4 bits (115), Expect = 4e-05
Identities = 48/197 (24%), Positives = 85/197 (43%), Gaps = 3/197 (1%)
Frame = +2
Query: 44 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 223
K KVGI+G+G++G A + A G V L D I A K L+K + RG
Sbjct: 321 KVSKVGILGAGMMGAGIAYVSAKAGIDVVLLDT---SIEAAEKGKDYSSKLLDK-AIARG 376
Query: 224 NLNADEQFQCVKGTCDLAIA---VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 394
+ +++ Q + + A ++D + E V E++++K +N + V+ + I
Sbjct: 377 R-STEQKKQALLDKINTTTAYDDLEDCDLIIEAVFEDIDIKAACTRNTEAVIAETAIYAS 435
Query: 395 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQ 574
+ K Q I H +P +PLVEI+ T K + +I +
Sbjct: 436 NTSTLPITELAKASKRPNQFIGLHFFSPVDKMPLVEIIVGEETDDATLAKGFDYVGQIAK 495
Query: 575 EPVTLSREIDGFVLNRI 625
P+ ++ + GF +R+
Sbjct: 496 TPIVVN-DSRGFYTSRV 511
>UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 723
Score = 50.0 bits (114), Expect = 5e-05
Identities = 47/201 (23%), Positives = 87/201 (43%), Gaps = 1/201 (0%)
Frame = +2
Query: 47 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 226
+ +VG++G GL+G + + A+ G V + + + A+ ++ L K +
Sbjct: 328 ARRVGVLGGGLMGSGISFVTANAGIPVRIRERDDAAAGKALGSVRALLDERVKRRSI-DR 386
Query: 227 LNADEQFQCVKGTCDLA-IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
L DE+ + V T D + A D + E V E+L LK+++ + + V+ I
Sbjct: 387 LERDERMRLVTATTDWSGYAAVDVLI--EAVFEDLALKQEMVRAFE-AVNPTGIFASNTS 443
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
E H V+ H +P +PL+EI+ T E T A+ ++ G+ +
Sbjct: 444 SIPITKIAEASAHPETVLGMHYFSPVQKMPLLEIIVTEKTSKEATATAVALGKKQGKTVI 503
Query: 584 TLSREIDGFVLNRIQYAILGE 646
+ + GF +RI + E
Sbjct: 504 VVG-DGPGFYTSRILAPYMNE 523
>UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Verminephrobacter eiseniae (strain
EF01-2)
Length = 319
Score = 50.0 bits (114), Expect = 5e-05
Identities = 42/186 (22%), Positives = 73/186 (39%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 241
++G+G++G + A G V ++D+ E+ + A + D + +
Sbjct: 9 VLGAGVLGGQISWHSAFKGKSVVVYDISEEALARCRAAQAHYAAIYQTDAVGASEADVAG 68
Query: 242 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 421
Q + DLA AV A V E VPE ++K V+Q + ++ +T+
Sbjct: 69 ARQRLTFATDLASAVASADLVIEAVPEIPQVKTSVYQQMAPLLPAHTLIATNSSTFLPSD 128
Query: 422 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREI 601
+ H N + LVEI+P T E G P+ + +E
Sbjct: 129 FAAATGRPDKFCALHYANYIWAANLVEIMPHAATARTTLDDVTRFAIETGMVPIPVGKEH 188
Query: 602 DGFVLN 619
+G+VLN
Sbjct: 189 NGYVLN 194
>UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Corynebacterium efficiens|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 755
Score = 49.6 bits (113), Expect = 6e-05
Identities = 48/193 (24%), Positives = 87/193 (45%), Gaps = 5/193 (2%)
Frame = +2
Query: 62 IVGSGLIGRSWAMLFASVGYQVTLFD--VVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
++G+G +G A L A+ G VTL D + + + +A+ ++ + +++ R ++
Sbjct: 17 VIGAGSMGAGIATLLANAGITVTLLDRHSGDPEDPNRLAESGLE-RQIQRGAFYRPEFSS 75
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
Q D A+ A ++ E V E+L +K F+ ++ ++
Sbjct: 76 RIQ---TGNIVDDTAALTRADWIIEAVFEDLTVKHDTFRLIEEHRSPGSLVSSNTSTIPL 132
Query: 416 XXXXENM--KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV-TKKTRAIMEEIGQEPVT 586
E M + + H NPP + LVE+V P T P+ T TR I +++G+ V
Sbjct: 133 AQLTEVMGTPMRLDFAIVHFFNPPTTMRLVELVTGPDTTPKTATDLTRIIEQQLGKV-VL 191
Query: 587 LSREIDGFVLNRI 625
R+ GF+ NRI
Sbjct: 192 HCRDTPGFIANRI 204
>UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=1; Plesiocystis
pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Plesiocystis pacifica SIR-1
Length = 789
Score = 49.6 bits (113), Expect = 6e-05
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 269 DLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKA 448
DL AV ++ V E + E L++K+ VF+ + + TI E + A
Sbjct: 71 DLERAVAESDIVIEAIIERLDIKQTVFKKVAAAAKETTILASNTSGIPIADIAEALDEGA 130
Query: 449 Q--VIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREIDGFVLNR 622
+ + H NPP ++ L+E++P+ +T + + +E+ + V L R+ F+ NR
Sbjct: 131 RERFLGLHFFNPPRWMHLLEVIPSKYTAKKYVDEVAKFSDEVLGKGVVLCRDTPNFIGNR 190
Query: 623 I 625
I
Sbjct: 191 I 191
>UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein
NCU04393.1; n=2; Sordariales|Rep: Putative
uncharacterized protein NCU04393.1 - Neurospora crassa
Length = 420
Score = 49.6 bits (113), Expect = 6e-05
Identities = 52/211 (24%), Positives = 93/211 (44%), Gaps = 19/211 (9%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVE-------KQITDAIADIKVQLKT---- 196
+ V I+G+G IGR A+++AS VT++D+ + + ITD +A ++ T
Sbjct: 93 QPVLIMGAGHIGRRVALVWASALRPVTVYDISKNALRSSTEYITDNLAKYCLEHGTHPGP 152
Query: 197 LEKDGLLRGNLNADEQ------FQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNL 358
+ LR A ++ F T + K V EC+PENL LK +
Sbjct: 153 VHFTSDLREATTAGKRHGLKLDFSAAHDTEPKSTRKKGPWMVIECLPENLSLKIAALAEI 212
Query: 359 DNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVT 538
+ ++ +N I +++H ++I +H PP V +VE++ + T +
Sbjct: 213 ERLLPENCIIASNSSSLMTSEMAPHLQHPGRLINTHYYIPPRNV-MVEVMSSSHTYEGIF 271
Query: 539 KKTRAIMEEIGQEPVTLSREI--DGFVLNRI 625
M+ +G P+ + + GF+ NRI
Sbjct: 272 PFLTREMKNMGLTPMVVPPGVQSQGFIFNRI 302
>UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 296
Score = 49.2 bits (112), Expect = 9e-05
Identities = 48/197 (24%), Positives = 81/197 (41%), Gaps = 1/197 (0%)
Frame = +2
Query: 59 GIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK-TLEKDGLLRGNLNA 235
GIVG+G GR A L A+ G +V + E+++ A + + L+ +EK L + A
Sbjct: 7 GIVGTGPSGRGIAQLVATQGLEVIMVGRSEEELEQARRQLDLALQHEIEKWALTQSEKRA 66
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
+ T D+ K + V E E K++F+ LD V I
Sbjct: 67 --ILARISMTTDINELAKADFVIATLVVEIAE-DKEIFRTLDQVCRREVILASNTSTLSI 123
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+VI H + P +V++V T E + A+ME +G+ V +
Sbjct: 124 TEMASATNRPDKVIGCHFLQPIPRTRVVQVVRGLKTSDETVSQVMALMERLGRTGVEVF- 182
Query: 596 EIDGFVLNRIQYAILGE 646
E G++ R+ ++ E
Sbjct: 183 ESPGYITTRLIVPLINE 199
>UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=7; Streptococcus agalactiae|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Streptococcus agalactiae
serotype Ia
Length = 377
Score = 49.2 bits (112), Expect = 9e-05
Identities = 31/115 (26%), Positives = 50/115 (43%)
Frame = +2
Query: 281 AVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIV 460
AV DA V E VPE + +K+ ++ L V TI + + +
Sbjct: 168 AVSDADLVIEAVPETVSIKEDFYKQLAKVAPSKTIFATNSSTLVPSQFADITGRPDKFLA 227
Query: 461 SHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREIDGFVLNRI 625
H N + +VEI+ T EV K+ ++IG P+ + +E G++LN I
Sbjct: 228 MHFANNIWQNNIVEIMGHKGTDDEVIKEALTFSKDIGMVPLHIHKEQPGYILNSI 282
>UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=23; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 733
Score = 49.2 bits (112), Expect = 9e-05
Identities = 47/191 (24%), Positives = 78/191 (40%), Gaps = 8/191 (4%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVE------KQITDAIAD--IKVQLKTLEK 205
+KVGI+G+G++G A + A G +V L D + K ++ + D +K T EK
Sbjct: 328 KKVGIIGAGMMGAGIAYVSALAGIEVVLIDAAQDSADRGKAYSEGLLDKGMKRGKVTEEK 387
Query: 206 DGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 385
+ G + A + + G CDL + +A+F V + K + N D + NT
Sbjct: 388 KAKVLGQITATTDYDALNG-CDLIV---EAVFEDPKVKAEVTAKAEAAMNADGIFATNTS 443
Query: 386 XXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEE 565
E Q I H +P + LVEI+ T K + +
Sbjct: 444 TLPITMLAKASSRAE------QFIGIHFFSPVDKMALVEIIKGKQTGDVAVAKALDFVRQ 497
Query: 566 IGQEPVTLSRE 598
I + P+ ++ E
Sbjct: 498 IRKTPIVVNDE 508
>UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Sphingomonas sp. SKA58
Length = 722
Score = 49.2 bits (112), Expect = 9e-05
Identities = 49/206 (23%), Positives = 90/206 (43%), Gaps = 3/206 (1%)
Frame = +2
Query: 38 KFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFD---VVEKQITDAIADIKVQLKTLEKD 208
KF+++KVG++G+G++G A + A+ G V L D ++ D A KV K +EK
Sbjct: 310 KFEAKKVGVLGAGMMGAGIAFVSANAGIDVVLIDRDTATAQKGKDYSA--KVLGKLVEKG 367
Query: 209 GLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIX 388
L + AD + T D A+ + V E V E+ +K + + + V+ I
Sbjct: 368 KLTQD--KADAVLARITPTDDFAL-LDGCDMVVEAVFEDTAIKAETTKKAEAVLPAQAIF 424
Query: 389 XXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEI 568
+ + Q I H +P + LVE++ T E K + ++
Sbjct: 425 ASNTSTLPISQLAQASRSPDQFIGLHFFSPVDRMGLVEVIMGKQTSKETLAKGLDFIAQL 484
Query: 569 GQEPVTLSREIDGFVLNRIQYAILGE 646
+ P+ ++ + GF +R+ ++ E
Sbjct: 485 RKTPIVVN-DSRGFYTSRVFQMLIHE 509
>UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Ralstonia metallidurans
(strain CH34 / ATCC 43123 / DSM 2839)
Length = 714
Score = 49.2 bits (112), Expect = 9e-05
Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 3/195 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
++VGI+G+G++G A A G + L DV D K+ + L + G+ +G +
Sbjct: 316 KRVGILGAGMMGAGIAYASAMRGIEAVLKDV----SLDHAGKGKLHSEKLLEKGVSKGKI 371
Query: 230 N---ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 400
+ DE Q + T D A + + E V E ELK +V + + + +N +
Sbjct: 372 SPSKRDEVLQRITPTAD-ASGLAGCDIIIEAVYEKRELKAEVTREAEPHLAENGLFASNT 430
Query: 401 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEP 580
E I H +P +PLVEI+ T +++IG+ P
Sbjct: 431 STLPITGLAEASASPENFIGLHFFSPVDRMPLVEIIKGKKTSSRTLAHAIDFVKQIGKTP 490
Query: 581 VTLSREIDGFVLNRI 625
+ ++ + GF +R+
Sbjct: 491 IVVN-DSRGFFTSRV 504
>UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit
FadJ; n=2; Cystobacterineae|Rep: Fatty oxidation
complex, alpha subunit FadJ - Myxococcus xanthus (strain
DK 1622)
Length = 746
Score = 49.2 bits (112), Expect = 9e-05
Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 2/201 (0%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASV-GYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRG 223
+KV ++G GL+G A + + + G V + D + + A+ ++ L + +++ L R
Sbjct: 350 KKVAVLGGGLMGGGIAYVTSVLQGVPVRVKDKDDAGVGRAMKQVQSILDERVKRRSLTRR 409
Query: 224 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
A V D + K A V E V E+L+LK ++ ++ V D TI
Sbjct: 410 EATAKSAL--VTAGTDYS-GFKSADLVIEAVFEDLKLKHRIIAEVEAVTGDQTIFASNTS 466
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+ + AQVI H +P + +PL+EI+ T VT + + G+ +
Sbjct: 467 SIPITELAKGSRRPAQVIGMHYFSPVHKMPLLEIITHAGTADWVTATCVEVGRKQGKTVI 526
Query: 584 TLSREIDGFVLNRIQYAILGE 646
++ + GF +RI + E
Sbjct: 527 VVN-DGPGFYTSRILAPYMNE 546
>UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein ech-8 - Caenorhabditis elegans
Length = 437
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/192 (21%), Positives = 80/192 (41%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
+ V ++G G +GR A+ F G++ L +V K ++++ K EK +
Sbjct: 40 KSVAVIGGGTMGRGIAIAFCLSGFETYLVEVNNKAAEFCKNELEITYKR-EKAFRRLNDS 98
Query: 230 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
++ + ++ T D + + + E V E+++LKK++F LD + + I
Sbjct: 99 KVEKLRKNLQITTDFQ-KLNNCDLIVEAVFEDMKLKKELFTKLDKICKPSCIFGTNTSSL 157
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
++ +V+ H NP + +VE++ T + I + PV L
Sbjct: 158 DLNEMSSVLRDPTKVVGIHFFNPANLIRMVEVIYGSKTSSKAVATAFEACRSIKKLPV-L 216
Query: 590 SREIDGFVLNRI 625
FV NR+
Sbjct: 217 VGNCPAFVFNRL 228
>UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Xanthomonadaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 693
Score = 48.8 bits (111), Expect = 1e-04
Identities = 51/198 (25%), Positives = 87/198 (43%), Gaps = 1/198 (0%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V ++G G++G A A G+ VTL D ++ I A+ KD R + A
Sbjct: 320 VHVIGVGVMGGDIAAWAAYKGFDVTLQDREQRFIDTALTRGGELFAKRVKDDAKRPAVAA 379
Query: 236 DEQFQCVKGTCDLAIA-VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
++G DLA A V A V E + EN + K+ ++Q+++ + + +
Sbjct: 380 R-----LRG--DLAGAGVTQADLVIEAIIENPQAKRDLYQSIEPQLKPDALLTTNTSSIP 432
Query: 413 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLS 592
+++ AQ H NP +PLVEIV P + A + + + PV ++
Sbjct: 433 LTDLRGHIQRPAQFAGLHYFNPVAMMPLVEIVQHDGLDPANVARLAAFCKTLDKFPVPVA 492
Query: 593 REIDGFVLNRIQYAILGE 646
GF++NR+ + L E
Sbjct: 493 -GTPGFLVNRVLFPYLLE 509
>UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Photobacterium profundum 3TCK|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Photobacterium profundum 3TCK
Length = 713
Score = 48.8 bits (111), Expect = 1e-04
Identities = 41/191 (21%), Positives = 84/191 (43%), Gaps = 1/191 (0%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+VG++G+G++G A + A G V + D+ + + + + L + G + L
Sbjct: 314 EVGVIGAGIMGGGIAYVTADKGADVVMKDINKAGLALGLTEANKLLAAQVERGRKKP-LA 372
Query: 233 ADEQFQCVKGTC-DLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
E ++ T + + D I E V EN ++K+ V L+ V + T+
Sbjct: 373 MGETLNRIQSTLYNQPLTSNDLII--EAVVENPKIKEAVLAELEQVSPNATLASNTSTLM 430
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ +K H NP + +PLVE++ T + + + ++G+ P+ +
Sbjct: 431 ISGLA-QALKKPENFCGIHFFNPVHKMPLVEVIRGEQTSDQTITQAVKYVSQLGKTPIVV 489
Query: 590 SREIDGFVLNR 622
+ + GF++NR
Sbjct: 490 N-DCAGFLVNR 499
>UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC
17978|Rep: PaaC - Acinetobacter baumannii (strain ATCC
17978 / NCDC KC 755)
Length = 435
Score = 48.8 bits (111), Expect = 1e-04
Identities = 35/125 (28%), Positives = 56/125 (44%)
Frame = +2
Query: 281 AVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIV 460
A++DA V E V E E+K+ +F+ L + TI + H +V+
Sbjct: 7 ALRDADLVIEAVVEKKEVKQSLFKQLAEICSAQTIFASNTSSISVTAISAGIAHPERVVG 66
Query: 461 SHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSREIDGFVLNRIQYAIL 640
H NP + LVEIV T + + +M + + PV L++ GF++NRI
Sbjct: 67 LHFFNPAPVMKLVEIVQGLKTPNSLCLALKNLMLDWKKIPV-LTKSTPGFIVNRIARPFY 125
Query: 641 GEVWR 655
E +R
Sbjct: 126 AEGFR 130
>UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Symbiobacterium thermophilum|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Symbiobacterium
thermophilum
Length = 190
Score = 48.4 bits (110), Expect = 1e-04
Identities = 41/184 (22%), Positives = 74/184 (40%), Gaps = 2/184 (1%)
Frame = +2
Query: 50 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 229
E++ ++G + G A L A GY L + + + +A ++ +L + +G G
Sbjct: 2 ERITVIGGTVAGVEIAALMARAGYATCLHEPDQAALAEAGRRLQDRLLGRQGEG---GGA 58
Query: 230 NADEQFQCVKGTCDLA--IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 403
+ Q V+ + +AV DA V E +L K+++F LD+ + I
Sbjct: 59 ASVAQLAAVRVRLEAVPEVAVADADLVIEASSVDLPGKRELFARLDSFAPAHAILATCSP 118
Query: 404 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPV 583
+V+ +PP P V ++ P PEV ++ G+EP+
Sbjct: 119 TISSAYLAAATSRPDRVVSLGFFSPPLAPPAVAVIQEPHLAPEVVAAVAEVVWRTGREPL 178
Query: 584 TLSR 595
L R
Sbjct: 179 LLRR 182
>UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation
complex; n=5; Betaproteobacteria|Rep: Alpha-subunit of
fatty acid oxidation complex - Azoarcus sp. (strain
EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 678
Score = 48.4 bits (110), Expect = 1e-04
Identities = 48/197 (24%), Positives = 87/197 (44%), Gaps = 6/197 (3%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+V +VG+G++G A + A G VTL D ++I A+ K E+ LRG+
Sbjct: 318 RVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGR---AAKLFERK--LRGD-T 371
Query: 233 ADEQFQCVKGTCDLAI------AVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 394
A + Q V+ D I + A V E + ENL+ K+ +F L+ + +
Sbjct: 372 ATKARQ-VRFALDRLIPDPHGHGARRADVVIEAIFENLDAKRALFAQLERRARPDAVLAT 430
Query: 395 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQ 574
+ + A+++ H NP +PLVE+V + + + A + + +
Sbjct: 431 NTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDADALYRAAAFVRRLDK 490
Query: 575 EPVTLSREIDGFVLNRI 625
P+ + R GF++N +
Sbjct: 491 LPLPV-RSAPGFLVNAV 506
>UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Magnetococcus sp. MC-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Magnetococcus sp. (strain MC-1)
Length = 717
Score = 48.4 bits (110), Expect = 1e-04
Identities = 46/200 (23%), Positives = 88/200 (44%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V +VG G++GR+ A+ A G QV+L + + + A+ + + D L +L
Sbjct: 312 VHVVGDGVMGRAIAVWCALQGMQVSLQGLSTELLGRALQEATQLARKKRLDRLATRDL-L 370
Query: 236 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 415
D +G V A V E + E++ K++++ L+ + ++ +
Sbjct: 371 DRLMPDQRGD-----GVCHADLVIEAIFEDVTAKQQLYAALEPRMREHALLATNTSAIPL 425
Query: 416 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTLSR 595
+ +K Q++ H NP +PLVE+V P T + + + I + P+ + +
Sbjct: 426 QTLAQGLKRPQQLLGLHFFNPVARMPLVEVVEGPQTSMQALQMGYRFVHAIQRLPLPV-K 484
Query: 596 EIDGFVLNRIQYAILGEVWR 655
GF++NR+ L E R
Sbjct: 485 SRPGFLVNRVLMPYLMEAVR 504
>UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Geobacter sp. FRC-32|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Geobacter sp. FRC-32
Length = 311
Score = 48.0 bits (109), Expect = 2e-04
Identities = 47/196 (23%), Positives = 78/196 (39%), Gaps = 5/196 (2%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEK-----DGLL 217
K I+G+G++GR W A G++V D + + +A + T K D
Sbjct: 2 KFAILGTGIMGRGWITQCAMSGHEVHCHDASPQTLAGTVAGCEKLAATAAKKFKHDDPNF 61
Query: 218 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 397
N + KG A K E + E+L+LK V + + + +
Sbjct: 62 VSNAMGKIRVHNEKGA--FIDAAKGCDVFLEVIFEDLKLKCSVLADYLPQLPPSVVFWSN 119
Query: 398 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQE 577
+ + IV+H +NP +P VE+VP T E + TR + + +
Sbjct: 120 SSSLDIDPMAQAGGRPDRSIVTHGMNPVPLMPGVEVVPGAKTSSETIEFTRQTLLNMKKA 179
Query: 578 PVTLSREIDGFVLNRI 625
P L+ I GF +NR+
Sbjct: 180 PF-LAPNIPGFWVNRL 194
>UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Reinekea sp. MED297|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Reinekea sp. MED297
Length = 705
Score = 48.0 bits (109), Expect = 2e-04
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 2/193 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
++G+VG+G++G A AS G V L D + + K + L RG L+
Sbjct: 315 RIGVVGAGMMGAGIAWACASKGLPVVLVDTEQSRAEQG----KGYSERLVAKRFERGRLS 370
Query: 233 ADEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 406
A+E + + + + V E V E+ LK V+Q + +VV TI
Sbjct: 371 AEEGTALLNRITPTESMSELAECDLVIEAVFEDRALKADVYQLIQSVVSPETIIASNTST 430
Query: 407 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+ Q I H +P +PL+EI+ T A +I + P+
Sbjct: 431 LPISSLAGMVDRPDQFIGLHFFSPVDKMPLLEIIRGEQTSKSTVNAALAFSHQITKTPIV 490
Query: 587 LSREIDGFVLNRI 625
++ + GF +R+
Sbjct: 491 VN-DGRGFYTSRV 502
>UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Frankia alni ACN14a|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Frankia alni
(strain ACN14a)
Length = 234
Score = 47.6 bits (108), Expect = 3e-04
Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 2/127 (1%)
Frame = +2
Query: 281 AVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIV 460
AV A V E VPE+L LK +VF+ LD V + +V+
Sbjct: 70 AVAGAAVVIEAVPEDLALKVRVFRELDRVAAAGAVLATNSSGFPVGALAAATDRPTRVLG 129
Query: 461 SHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL--SREIDGFVLNRIQYA 634
H +P + EIV T P+ + +G+ PV + + G+V NR+ +A
Sbjct: 130 WHWSSPAQIMRFAEIVVTEHTDPDAVATVTRLAHGLGKNPVVVRDAPMAWGYVANRVYWA 189
Query: 635 ILGEVWR 655
+ E R
Sbjct: 190 AVAEARR 196
>UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=2;
Cystobacterineae|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Stigmatella aurantiaca DW4/3-1
Length = 797
Score = 47.6 bits (108), Expect = 3e-04
Identities = 48/203 (23%), Positives = 91/203 (44%), Gaps = 12/203 (5%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVV-------EKQITDAIADIKVQLKTLEKDG 211
KV ++G+G++G A A+ G + L D+V E + A + K L L
Sbjct: 7 KVAVLGAGVMGSGIAAHLANSGVRALLLDIVPPKAGPGEDTSSKAFRN-KFVLGALANLR 65
Query: 212 LLRGNLNADEQ-FQCVK-GTCDLAIA-VKDAIFVQECVPENLELKKKVFQNLDNVVDDNT 382
+ + EQ F ++ G + IA + + +V E V E+L +K+ +F+ ++ + +
Sbjct: 66 KQKPSPIVSEQVFASLEVGNLEDDIARIAECDWVIEVVKEDLAVKQALFEKVEKHLRKDA 125
Query: 383 IXXXXXXXXXXXXXXENM--KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAI 556
I + + + + +V+H NP Y+ L+E+V P T P V + A
Sbjct: 126 IVSSNTSGLSIAGMLQGRGPEFRKRFLVTHFFNPVRYMKLLELVAGPETDPAVVRTLHAF 185
Query: 557 MEEIGQEPVTLSREIDGFVLNRI 625
E + + + ++ F+ NRI
Sbjct: 186 GEGVLGKGIVYGKDTTNFIANRI 208
>UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Solibacter usitatus
Ellin6076|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Solibacter usitatus (strain
Ellin6076)
Length = 778
Score = 47.6 bits (108), Expect = 3e-04
Identities = 43/193 (22%), Positives = 78/193 (40%), Gaps = 2/193 (1%)
Frame = +2
Query: 53 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 232
+V ++G+G +G A FA+ G+ V L D+V A +++ K + +
Sbjct: 7 RVAVLGAGTMGARIAAHFANAGFPVDLLDLVLPDKPQRNALALAGIESAAKQRPVGFFTD 66
Query: 233 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 412
A + D V ++ E V ENLE+K+ ++Q + + I
Sbjct: 67 AAKTLITPGNFEDDLGRVGRCEWIVEAVAENLEIKRALWQRVAALRAPGAILSTNTSGIP 126
Query: 413 XXXXXENM--KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVT 586
+ + + +H NPP Y+ L E++P T PEV + + + V
Sbjct: 127 LAQISAGFDSEFRRHFLGTHFFNPPRYLHLAEVIPGAETNPEVLDWVSSFCDLHLGKGVV 186
Query: 587 LSREIDGFVLNRI 625
++ F+ NRI
Sbjct: 187 RCKDTPNFIANRI 199
>UniRef50_A3VIL7 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacterales bacterium HTCC2654
Length = 695
Score = 47.6 bits (108), Expect = 3e-04
Identities = 49/195 (25%), Positives = 78/195 (40%), Gaps = 2/195 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
VG+VG+G + R AM G VT V + AI ++ +++ D + G L+
Sbjct: 302 VGVVGAGALARDVAMAALKAGVPVT----VALEDDTAITRVRGRIERAFGDAVEAGTLSG 357
Query: 236 DEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
E+ ++ T D A+ D + E + E+ K + L V +TI
Sbjct: 358 RERDDRLRRLNTADDYGALDDKDVIIEALAEDSVRKTQALGQLSQVAAGHTIFASSTAEC 417
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+ H + P LVEI PA T+PE + +G+ PV L
Sbjct: 418 DIETLAGASGRPDRFAAMHFIAPADANRLVEIAPARGTRPEALMTLIRLARAMGKGPV-L 476
Query: 590 SREIDGFVLNRIQYA 634
+ G V NR++ A
Sbjct: 477 TGARQGLVYNRMRQA 491
>UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Serratia proteamaculans 568|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding - Serratia
proteamaculans 568
Length = 509
Score = 47.6 bits (108), Expect = 3e-04
Identities = 41/192 (21%), Positives = 86/192 (44%), Gaps = 2/192 (1%)
Frame = +2
Query: 56 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 235
V ++G+G +GR A L A G + L++ + A D ++ + DG G ++
Sbjct: 11 VAVIGAGTMGRGIAYLLAQNGIRTLLYNRSGNNLNQA-RDYIIRDLDKKIDG---GKISP 66
Query: 236 DEQFQCVKGTCDLAI--AVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 409
++ + + I A+ D+ V E + E+ K ++ + V I
Sbjct: 67 QKKGEILANLVFSPIFEAIADSDLVIETIAEHEATKHEILAAIAATVKKEAIIATNTSSL 126
Query: 410 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTRAIMEEIGQEPVTL 589
+++ A+ I H NP + L+EI+P+ +T + + + ++ IG++ V +
Sbjct: 127 SLNKLAAGVENNARFIGLHFFNPAPLMKLIEIIPSYFTSRATSLRCQQLVTAIGKQFV-V 185
Query: 590 SREIDGFVLNRI 625
+ GF++NR+
Sbjct: 186 CKATPGFIVNRM 197
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 649,863,813
Number of Sequences: 1657284
Number of extensions: 12681989
Number of successful extensions: 42922
Number of sequences better than 10.0: 409
Number of HSP's better than 10.0 without gapping: 41087
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42672
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49173558301
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -