Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0001_C19
(639 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 116 5e-26
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 116 5e-26
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 116 5e-26
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 116 5e-26
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 110 5e-24
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 97 5e-20
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 56 8e-08
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 56 8e-08
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 56 8e-08
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 56 8e-08
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 41 0.004
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 41 0.004
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 41 0.004
AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent 15-hydro... 41 0.004
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 41 0.004
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 40 0.006
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 40 0.007
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 40 0.007
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 40 0.010
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 40 0.010
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 40 0.010
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 39 0.013
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 38 0.030
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 38 0.030
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 37 0.053
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 37 0.053
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 37 0.053
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 37 0.053
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 37 0.053
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 37 0.053
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 37 0.053
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 37 0.053
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 37 0.053
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 37 0.053
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 37 0.069
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 36 0.092
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 36 0.092
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 36 0.12
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 36 0.16
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 36 0.16
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 36 0.16
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 35 0.28
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 34 0.37
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 34 0.37
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 34 0.37
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 34 0.37
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 34 0.37
D87717-1|BAA13442.2| 1086|Homo sapiens KIAA0013 protein. 33 0.65
BC063444-1|AAH63444.1| 501|Homo sapiens Rho GTPase activating p... 33 0.65
BC039563-1|AAH39563.1| 1023|Homo sapiens Rho GTPase activating p... 33 0.65
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 32 1.5
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 32 2.0
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 32 2.0
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 32 2.0
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 31 3.4
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 31 3.4
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 31 3.4
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 31 3.4
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 31 4.6
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 31 4.6
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 31 4.6
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 31 4.6
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 31 4.6
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 31 4.6
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 31 4.6
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 30 6.0
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 116 bits (280), Expect = 5e-26
Identities = 64/185 (34%), Positives = 103/185 (55%)
Frame = +1
Query: 85 VNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAK 264
+++ KV LVT ALL + A+ VA +D + G +A L +F +
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALHEQFEPQKTL 59
Query: 265 FIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDERSFKKMIDINFTATVNSTLK 444
FI+CDVAD QL + +V+D + RLD ++NNA V + E++++K + IN + ++ T
Sbjct: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--EKNWEKTLQINLVSVISGTYL 117
Query: 445 GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQVR 624
GLD M GG GG+++NMSSL L P + PVY A+K ++ F+ + M + VR
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177
Query: 625 VLSVC 639
+ ++C
Sbjct: 178 LNAIC 182
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 116 bits (280), Expect = 5e-26
Identities = 64/185 (34%), Positives = 103/185 (55%)
Frame = +1
Query: 85 VNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAK 264
+++ KV LVT ALL + A+ VA +D + G +A L +F +
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALHEQFEPQKTL 59
Query: 265 FIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDERSFKKMIDINFTATVNSTLK 444
FI+CDVAD QL + +V+D + RLD ++NNA V + E++++K + IN + ++ T
Sbjct: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--EKNWEKTLQINLVSVISGTYL 117
Query: 445 GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQVR 624
GLD M GG GG+++NMSSL L P + PVY A+K ++ F+ + M + VR
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177
Query: 625 VLSVC 639
+ ++C
Sbjct: 178 LNAIC 182
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 116 bits (280), Expect = 5e-26
Identities = 64/185 (34%), Positives = 103/185 (55%)
Frame = +1
Query: 85 VNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAK 264
+++ KV LVT ALL + A+ VA +D + G +A L +F +
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTL 59
Query: 265 FIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDERSFKKMIDINFTATVNSTLK 444
FI+CDVAD QL + +V+D + RLD ++NNA V + E++++K + IN + ++ T
Sbjct: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--EKNWEKTLQINLVSVISGTYL 117
Query: 445 GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQVR 624
GLD M GG GG+++NMSSL L P + PVY A+K ++ F+ + M + VR
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177
Query: 625 VLSVC 639
+ ++C
Sbjct: 178 LNAIC 182
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 116 bits (280), Expect = 5e-26
Identities = 64/185 (34%), Positives = 103/185 (55%)
Frame = +1
Query: 85 VNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAK 264
+++ KV LVT ALL + A+ VA +D + G +A L +F +
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTL 59
Query: 265 FIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDERSFKKMIDINFTATVNSTLK 444
FI+CDVAD QL + +V+D + RLD ++NNA V + E++++K + IN + ++ T
Sbjct: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--EKNWEKTLQINLVSVISGTYL 117
Query: 445 GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQVR 624
GLD M GG GG+++NMSSL L P + PVY A+K ++ F+ + M + VR
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177
Query: 625 VLSVC 639
+ ++C
Sbjct: 178 LNAIC 182
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 110 bits (264), Expect = 5e-24
Identities = 59/165 (35%), Positives = 94/165 (56%)
Frame = +1
Query: 85 VNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAK 264
+++ KV LVT ALL + A+ VA +D + G +A L +F +
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTL 59
Query: 265 FIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDERSFKKMIDINFTATVNSTLK 444
FI+CDVAD QL + +V+D + RLD ++NNA V + +++++K + IN + ++ T
Sbjct: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--KKNWEKTLQINLVSVISGTYL 117
Query: 445 GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFS 579
GLD M GG GG+++NMSSL L P + PVY A+K ++ F+
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFT 162
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 97.1 bits (231), Expect = 5e-20
Identities = 53/144 (36%), Positives = 82/144 (56%)
Frame = +1
Query: 85 VNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAK 264
+++ KV LVT ALL + A+ VA +D + G +A L +F +
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTL 59
Query: 265 FIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDERSFKKMIDINFTATVNSTLK 444
FI+CDVAD QL + +V+D + RLD ++NNA V +E++++K + IN + ++ T
Sbjct: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--NNEKNWEKTLQINLVSVISGTYL 117
Query: 445 GLDCMGIDKGGRGGVVVNMSSLLA 516
GLD M GG GG+++NMSSL A
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAA 141
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 56.4 bits (130), Expect = 8e-08
Identities = 52/185 (28%), Positives = 79/185 (42%), Gaps = 7/185 (3%)
Frame = +1
Query: 100 KVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKFIKCD 279
KV +VT RA ++ AR V D G ALE EL A FI CD
Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG------AVFILCD 62
Query: 280 VADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDER-------SFKKMIDINFTATVNST 438
V D + + + ++ RLD V+NNA +R F++++++N T T
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 439 LKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQ 618
L + +G V+N+SSL+ + Y ATK AV + A+ D+ +
Sbjct: 123 KLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 619 VRVLS 633
V +S
Sbjct: 179 VNCIS 183
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 56.4 bits (130), Expect = 8e-08
Identities = 52/185 (28%), Positives = 79/185 (42%), Gaps = 7/185 (3%)
Frame = +1
Query: 100 KVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKFIKCD 279
KV +VT RA ++ AR V D G ALE EL A FI CD
Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG------AVFILCD 62
Query: 280 VADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDER-------SFKKMIDINFTATVNST 438
V D + + + ++ RLD V+NNA +R F++++++N T T
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 439 LKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQ 618
L + +G V+N+SSL+ + Y ATK AV + A+ D+ +
Sbjct: 123 KLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 619 VRVLS 633
V +S
Sbjct: 179 VNCIS 183
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 56.4 bits (130), Expect = 8e-08
Identities = 52/185 (28%), Positives = 79/185 (42%), Gaps = 7/185 (3%)
Frame = +1
Query: 100 KVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKFIKCD 279
KV +VT RA ++ AR V D G ALE EL A FI CD
Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG------AVFILCD 62
Query: 280 VADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDER-------SFKKMIDINFTATVNST 438
V D + + + ++ RLD V+NNA +R F++++++N T T
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 439 LKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQ 618
L + +G V+N+SSL+ + Y ATK AV + A+ D+ +
Sbjct: 123 KLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 619 VRVLS 633
V +S
Sbjct: 179 VNCIS 183
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 56.4 bits (130), Expect = 8e-08
Identities = 52/185 (28%), Positives = 79/185 (42%), Gaps = 7/185 (3%)
Frame = +1
Query: 100 KVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKFIKCD 279
KV +VT RA ++ AR V D G ALE EL A FI CD
Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG------AVFILCD 62
Query: 280 VADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDER-------SFKKMIDINFTATVNST 438
V D + + + ++ RLD V+NNA +R F++++++N T T
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 439 LKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQ 618
L + +G V+N+SSL+ + Y ATK AV + A+ D+ +
Sbjct: 123 KLALPYLRKSQGN----VINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 619 VRVLS 633
V +S
Sbjct: 179 VNCIS 183
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 40.7 bits (91), Expect = 0.004
Identities = 48/181 (26%), Positives = 77/181 (42%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ MAS+ R + +KV LVT R L + A HV ++ R+ ++
Sbjct: 17 VRMASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGA-HVV---VSSRKQQNVDQA 72
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L C V + + + +D +++NAAV + V E
Sbjct: 73 VATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEE 132
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K +DIN A T + M +K G G VV+ +SS+ A +PS Y +KTA+
Sbjct: 133 VWDKTLDINVKAPALMTKAVVPEM--EKRGGGSVVI-VSSIAAFSPSPGFSPYNVSKTAL 189
Query: 568 L 570
L
Sbjct: 190 L 190
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 40.7 bits (91), Expect = 0.004
Identities = 48/181 (26%), Positives = 77/181 (42%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ MAS+ R + +KV LVT R L + A HV ++ R+ ++
Sbjct: 17 VRMASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGA-HVV---VSSRKQQNVDQA 72
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L C V + + + +D +++NAAV + V E
Sbjct: 73 VATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEE 132
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K +DIN A T + M +K G G VV+ +SS+ A +PS Y +KTA+
Sbjct: 133 VWDKTLDINVKAPALMTKAVVPEM--EKRGGGSVVI-VSSIAAFSPSPGFSPYNVSKTAL 189
Query: 568 L 570
L
Sbjct: 190 L 190
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 40.7 bits (91), Expect = 0.004
Identities = 48/181 (26%), Positives = 77/181 (42%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ MAS+ R + +KV LVT R L + A HV ++ R+ ++
Sbjct: 17 VRMASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGA-HVV---VSSRKQQNVDQA 72
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L C V + + + +D +++NAAV + V E
Sbjct: 73 VATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEE 132
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K +DIN A T + M +K G G VV+ +SS+ A +PS Y +KTA+
Sbjct: 133 VWDKTLDINVKAPALMTKAVVPEM--EKRGGGSVVI-VSSIAAFSPSPGFSPYNVSKTAL 189
Query: 568 L 570
L
Sbjct: 190 L 190
>AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 72
Score = 40.7 bits (91), Expect = 0.004
Identities = 25/72 (34%), Positives = 36/72 (50%)
Frame = +1
Query: 85 VNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAK 264
+++ KV LVT ALL + A+ VA +D + G +A L +F +
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTL 59
Query: 265 FIKCDVADGDQL 300
FI+CDVAD QL
Sbjct: 60 FIQCDVADQQQL 71
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 40.7 bits (91), Expect = 0.004
Identities = 48/179 (26%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +1
Query: 58 MASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELI 237
MAS+ R + +KV LVT R L + A HV ++ R+ ++ +
Sbjct: 1 MASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGA-HVV---VSSRKQQNVDQAVA 56
Query: 238 NKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDERSF 393
G L C V + + + +D +++NAAV + V E +
Sbjct: 57 TLQGEGLSVTGTVCHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVW 116
Query: 394 KKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVL 570
K +DIN A T + M +K G G VV+ +SS+ A +PS Y +KTA+L
Sbjct: 117 DKTLDINVKAPALMTKAVVPEM--EKRGGGSVVI-VSSIAAFSPSPGFSPYNVSKTALL 172
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 40.3 bits (90), Expect = 0.006
Identities = 48/179 (26%), Positives = 76/179 (42%), Gaps = 8/179 (4%)
Frame = +1
Query: 58 MASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELI 237
MAS+ R + +KV LVT R L + A HV ++ R+ ++ +
Sbjct: 1 MASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGA-HVV---VSSRKQQNVDQAVA 56
Query: 238 NKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDERSF 393
G L C V + + + +D +++NAAV + V E +
Sbjct: 57 TLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVW 116
Query: 394 KKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVL 570
K +DIN A T + M +K G G VV+ +SS+ A +PS Y +KTA+L
Sbjct: 117 DKTLDINVKAPALMTKAVVPEM--EKRGGGSVVI-VSSIAAFSPSPGFSPYNVSKTALL 172
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 39.9 bits (89), Expect = 0.007
Identities = 47/181 (25%), Positives = 77/181 (42%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ +AS+ R + +KV LVT R L + A HV ++ R+ ++
Sbjct: 15 VRLASSRMTRRDPLTNKVALVTASTDGIGFAIARRLAQDRA-HVV---VSSRKQQNVDQA 70
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L C V + + + +D +++NAAV + V E
Sbjct: 71 VATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEE 130
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K +DIN A T + M +K G G VV+ +SS+ A +PS Y +KTA+
Sbjct: 131 VWDKTLDINVKAPALMTKAVVPEM--EKRGGGSVVI-VSSIAAFSPSPGFSPYNVSKTAL 187
Query: 568 L 570
L
Sbjct: 188 L 188
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 39.9 bits (89), Expect = 0.007
Identities = 48/181 (26%), Positives = 77/181 (42%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ MAS+ R + +KV LVT R L + A HV ++ R+ ++
Sbjct: 17 VRMASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGA-HVV---VSSRKQQNVDQA 72
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L C V + + + +D +++NAAV + V E
Sbjct: 73 VATLQGEGLSVTGTVCMVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEE 132
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K +DIN A T + M +K G G VV+ +SS+ A +PS Y +KTA+
Sbjct: 133 VWDKTLDINVKAPALMTKAVVPEM--EKRGGGSVVI-VSSIAAFSPSPGFSPYNVSKTAL 189
Query: 568 L 570
L
Sbjct: 190 L 190
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 39.5 bits (88), Expect = 0.010
Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
Frame = +1
Query: 274 CDVADGDQLAAAYEQVLDKYRRLDGVINNAAV----LSVDERSFKKMIDINFTATVNSTL 441
CDVA + +E++ R++ ++N A + L V ++ + M+ T + S L
Sbjct: 55 CDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKT-EDMVSQLHTNLLGSML 113
Query: 442 KGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQV 621
M +GG +VN+ S++ L +S VY+A+K ++ FS A+ + K +V
Sbjct: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173
Query: 622 RVLS 633
V++
Sbjct: 174 NVVA 177
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 39.5 bits (88), Expect = 0.010
Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
Frame = +1
Query: 274 CDVADGDQLAAAYEQVLDKYRRLDGVINNAAV----LSVDERSFKKMIDINFTATVNSTL 441
CDVA + +E++ R++ ++N A + L V ++ + M+ T + S L
Sbjct: 55 CDVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKT-EDMVSQLHTNLLGSML 113
Query: 442 KGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQV 621
M +GG +VN+ S++ L +S VY+A+K ++ FS A+ + K +V
Sbjct: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173
Query: 622 RVLS 633
V++
Sbjct: 174 NVVA 177
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 39.5 bits (88), Expect = 0.010
Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
Frame = +1
Query: 274 CDVADGDQLAAAYEQVLDKYRRLDGVINNAAV----LSVDERSFKKMIDINFTATVNSTL 441
CDVA + +E++ R++ ++N A + L V ++ + M+ T + S L
Sbjct: 55 CDVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKT-EDMVSQLHTNLLGSML 113
Query: 442 KGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSIAMGSDDYYMKTQV 621
M +GG +VN+ S++ L +S VY+A+K ++ FS A+ + K +V
Sbjct: 114 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 173
Query: 622 RVLS 633
V++
Sbjct: 174 NVVA 177
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 39.1 bits (87), Expect = 0.013
Identities = 47/181 (25%), Positives = 76/181 (41%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ MAS+ R + +KV L T R L + A HV ++ R+ ++
Sbjct: 17 VRMASSGMTRRDPLANKVALATASTDGIGFAIARRLAQDGA-HVV---VSSRKQQNVDQA 72
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L C V + + + +D +++NAAV + V E
Sbjct: 73 VATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEE 132
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K +DIN A T + M +K G G VV+ +SS+ A +PS Y +KTA+
Sbjct: 133 VWDKTLDINVKAPALMTKAVVPEM--EKRGGGSVVI-VSSIAAFSPSPGFSPYNVSKTAL 189
Query: 568 L 570
L
Sbjct: 190 L 190
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 37.9 bits (84), Expect = 0.030
Identities = 41/189 (21%), Positives = 80/189 (42%), Gaps = 9/189 (4%)
Frame = +1
Query: 97 DKVFLVTXXXXXXXXXXXRALLSENARHVAFL-DIAVREGAALEAELINKFGALRAKFIK 273
D++ LVT RAL+ + + V + E A E + G L +
Sbjct: 11 DRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIP--YR 68
Query: 274 CDVADGDQLAAAYEQVLDKYRRLDGVINNA------AVLSVDERSFKKMIDINFTATVNS 435
CD+++ + + + + + ++ +D INNA +LS +K M ++N A
Sbjct: 69 CDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSIC 128
Query: 436 TLKGLDCMGIDKGGRGGVVVNMSSLLA--LNPSSHLPVYAATKTAVLQFSIAMGSDDYYM 609
T + M ++ G ++N++S+ + P S Y+ATK AV + + +
Sbjct: 129 TREAYQSMK-ERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREA 187
Query: 610 KTQVRVLSV 636
+T +R +
Sbjct: 188 QTHIRATCI 196
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 37.9 bits (84), Expect = 0.030
Identities = 41/189 (21%), Positives = 80/189 (42%), Gaps = 9/189 (4%)
Frame = +1
Query: 97 DKVFLVTXXXXXXXXXXXRALLSENARHVAFL-DIAVREGAALEAELINKFGALRAKFIK 273
D++ LVT RAL+ + + V + E A E + G L +
Sbjct: 11 DRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIP--YR 68
Query: 274 CDVADGDQLAAAYEQVLDKYRRLDGVINNA------AVLSVDERSFKKMIDINFTATVNS 435
CD+++ + + + + + ++ +D INNA +LS +K M ++N A
Sbjct: 69 CDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSIC 128
Query: 436 TLKGLDCMGIDKGGRGGVVVNMSSLLA--LNPSSHLPVYAATKTAVLQFSIAMGSDDYYM 609
T + M ++ G ++N++S+ + P S Y+ATK AV + + +
Sbjct: 129 TREAYQSMK-ERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREA 187
Query: 610 KTQVRVLSV 636
+T +R +
Sbjct: 188 QTHIRATCI 196
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 37.1 bits (82), Expect = 0.053
Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSI 582
N T N MG D+GG+ GV++N +S+ A Y+A+K ++ ++
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180
Query: 583 AMGSD 597
+ D
Sbjct: 181 PIARD 185
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 37.1 bits (82), Expect = 0.053
Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSI 582
N T N MG D+GG+ GV++N +S+ A Y+A+K ++ ++
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180
Query: 583 AMGSD 597
+ D
Sbjct: 181 PIARD 185
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 37.1 bits (82), Expect = 0.053
Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSI 582
N T N MG D+GG+ GV++N +S+ A Y+A+K ++ ++
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180
Query: 583 AMGSD 597
+ D
Sbjct: 181 PIARD 185
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 37.1 bits (82), Expect = 0.053
Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSI 582
N T N MG D+GG+ GV++N +S+ A Y+A+K ++ ++
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180
Query: 583 AMGSD 597
+ D
Sbjct: 181 PIARD 185
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 37.1 bits (82), Expect = 0.053
Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSI 582
N T N MG D+GG+ GV++N +S+ A Y+A+K ++ ++
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180
Query: 583 AMGSD 597
+ D
Sbjct: 181 PIARD 185
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 37.1 bits (82), Expect = 0.053
Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSI 582
N T N MG D+GG+ GV++N +S+ A Y+A+K ++ ++
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180
Query: 583 AMGSD 597
+ D
Sbjct: 181 PIARD 185
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 37.1 bits (82), Expect = 0.053
Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSI 582
N T N MG D+GG+ GV++N +S+ A Y+A+K ++ ++
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180
Query: 583 AMGSD 597
+ D
Sbjct: 181 PIARD 185
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 37.1 bits (82), Expect = 0.053
Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSI 582
N T N MG D+GG+ GV++N +S+ A Y+A+K ++ ++
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180
Query: 583 AMGSD 597
+ D
Sbjct: 181 PIARD 185
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 37.1 bits (82), Expect = 0.053
Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSI 582
N T N MG D+GG+ GV++N +S+ A Y+A+K ++ ++
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180
Query: 583 AMGSD 597
+ D
Sbjct: 181 PIARD 185
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 37.1 bits (82), Expect = 0.053
Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFSI 582
N T N MG D+GG+ GV++N +S+ A Y+A+K ++ ++
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL 180
Query: 583 AMGSD 597
+ D
Sbjct: 181 PIARD 185
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 36.7 bits (81), Expect = 0.069
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Frame = +1
Query: 205 REGAALEAELINKFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV----- 369
+EG ++ + GA R + CD + + + +QV + + +INNA +
Sbjct: 74 KEGNEETCKMAREAGATRVRAYTCDCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKK 133
Query: 370 -LSVDERSFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVY 546
L + +K D+NF A + + L M + G +V +SS L+ + L Y
Sbjct: 134 FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGH---LVCISSSAGLSGVNGLADY 190
Query: 547 AATKTAVLQFSIAMGSDDYYMKTQ-VRVLSVC 639
A+K A F+ ++ + + K + ++ VC
Sbjct: 191 CASKFAAFGFAESVFVETFVQKQKGIKTTIVC 222
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 36.3 bits (80), Expect = 0.092
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 6/115 (5%)
Frame = +1
Query: 241 KFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINN------AAVLSVDERSFKKM 402
K GA + +I D+A + + + LDK LD ++ N A + ++ + +
Sbjct: 75 KLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWL 134
Query: 403 IDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ +NF + V T + L + KG +V +SSLL P+S Y+A K A+
Sbjct: 135 MQVNFVSYVQLTSRALPSLTDSKGS----LVVVSSLLGRVPTSFSTPYSAAKFAL 185
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 36.3 bits (80), Expect = 0.092
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 6/115 (5%)
Frame = +1
Query: 241 KFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINN------AAVLSVDERSFKKM 402
K GA + +I D+A + + + LDK LD ++ N A + ++ + +
Sbjct: 75 KLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWL 134
Query: 403 IDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ +NF + V T + L + KG +V +SSLL P+S Y+A K A+
Sbjct: 135 MQVNFVSYVQLTSRALPSLTDSKGS----LVVVSSLLGRVPTSFSTPYSAAKFAL 185
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 35.9 bits (79), Expect = 0.12
Identities = 28/126 (22%), Positives = 52/126 (41%), Gaps = 15/126 (11%)
Frame = +1
Query: 265 FIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMID 408
F DV + A K+ R+D +N A + + F++++D
Sbjct: 10 FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 69
Query: 409 INFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQFS 579
+N T N MG D+GG+ GV++N +S+ A Y+A+K ++ +
Sbjct: 70 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 129
Query: 580 IAMGSD 597
+ + D
Sbjct: 130 LPIARD 135
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 35.5 bits (78), Expect = 0.16
Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 7/152 (4%)
Frame = +1
Query: 205 REGAALEAELINKFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV----- 369
+EG ++ + GA R CD + + + +QV + + +INNA +
Sbjct: 74 KEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKK 133
Query: 370 -LSVDERSFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVY 546
L + +K D+NF A + + L M + G +V +SS L+ + L Y
Sbjct: 134 FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGH---LVCISSSAGLSGVNGLADY 190
Query: 547 AATKTAVLQFSIAMGSDDYYMKTQ-VRVLSVC 639
A+K A F+ ++ + + K + ++ VC
Sbjct: 191 CASKFAAFGFAESVFVETFVQKQKGIKTTIVC 222
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 35.5 bits (78), Expect = 0.16
Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 7/152 (4%)
Frame = +1
Query: 205 REGAALEAELINKFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV----- 369
+EG ++ + GA R CD + + + +QV + + +INNA +
Sbjct: 74 KEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKK 133
Query: 370 -LSVDERSFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVY 546
L + +K D+NF A + + L M + G +V +SS L+ + L Y
Sbjct: 134 FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGH---LVCISSSAGLSGVNGLADY 190
Query: 547 AATKTAVLQFSIAMGSDDYYMKTQ-VRVLSVC 639
A+K A F+ ++ + + K + ++ VC
Sbjct: 191 CASKFAAFGFAESVFVETFVQKQKGIKTTIVC 222
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 35.5 bits (78), Expect = 0.16
Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 7/152 (4%)
Frame = +1
Query: 205 REGAALEAELINKFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV----- 369
+EG ++ + GA R CD + + + +QV + + +INNA +
Sbjct: 74 KEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKK 133
Query: 370 -LSVDERSFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVY 546
L + +K D+NF A + + L M + G +V +SS L+ + L Y
Sbjct: 134 FLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGH---LVCISSSAGLSGVNGLADY 190
Query: 547 AATKTAVLQFSIAMGSDDYYMKTQ-VRVLSVC 639
A+K A F+ ++ + + K + ++ VC
Sbjct: 191 CASKFAAFGFAESVFVETFVQKQKGIKTTIVC 222
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 34.7 bits (76), Expect = 0.28
Identities = 24/69 (34%), Positives = 37/69 (53%)
Frame = +1
Query: 364 AVLSVDERSFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPV 543
+++ V E + K +DIN A T + M +K G G VV+ +SS+ A +PS
Sbjct: 1 SLMDVTEEVWDKTLDINVKAPALMTKAVVPEM--EKRGGGSVVI-VSSIAAFSPSPGFSP 57
Query: 544 YAATKTAVL 570
Y +KTA+L
Sbjct: 58 YNVSKTALL 66
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 34.3 bits (75), Expect = 0.37
Identities = 30/106 (28%), Positives = 56/106 (52%), Gaps = 6/106 (5%)
Frame = +1
Query: 277 DVADGDQLAAAYEQVLDKYRRLDGVINNAAV----LSVDER--SFKKMIDINFTATVNST 438
D+ D AA + VL ++ R+D ++NN + L +D ++K+I++N+ TV+ T
Sbjct: 111 DLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLT 170
Query: 439 LKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQF 576
L M I++ + G +V ++S+L + Y A+K A+ F
Sbjct: 171 KCVLPHM-IER--KQGKIVTVNSILGIISVPLSIGYCASKHALRGF 213
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 34.3 bits (75), Expect = 0.37
Identities = 30/106 (28%), Positives = 56/106 (52%), Gaps = 6/106 (5%)
Frame = +1
Query: 277 DVADGDQLAAAYEQVLDKYRRLDGVINNAAV----LSVDER--SFKKMIDINFTATVNST 438
D+ D AA + VL ++ R+D ++NN + L +D ++K+I++N+ TV+ T
Sbjct: 111 DLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLT 170
Query: 439 LKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQF 576
L M I++ + G +V ++S+L + Y A+K A+ F
Sbjct: 171 KCVLPHM-IER--KQGKIVTVNSILGIISVPLSIGYCASKHALRGF 213
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 34.3 bits (75), Expect = 0.37
Identities = 30/106 (28%), Positives = 56/106 (52%), Gaps = 6/106 (5%)
Frame = +1
Query: 277 DVADGDQLAAAYEQVLDKYRRLDGVINNAAV----LSVDER--SFKKMIDINFTATVNST 438
D+ D AA + VL ++ R+D ++NN + L +D ++K+I++N+ TV+ T
Sbjct: 61 DLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLT 120
Query: 439 LKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQF 576
L M I++ + G +V ++S+L + Y A+K A+ F
Sbjct: 121 KCVLPHM-IER--KQGKIVTVNSILGIISVPLSIGYCASKHALRGF 163
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 34.3 bits (75), Expect = 0.37
Identities = 30/106 (28%), Positives = 56/106 (52%), Gaps = 6/106 (5%)
Frame = +1
Query: 277 DVADGDQLAAAYEQVLDKYRRLDGVINNAAV----LSVDER--SFKKMIDINFTATVNST 438
D+ D AA + VL ++ R+D ++NN + L +D ++K+I++N+ TV+ T
Sbjct: 111 DLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLT 170
Query: 439 LKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQF 576
L M I++ + G +V ++S+L + Y A+K A+ F
Sbjct: 171 KCVLPHM-IER--KQGKIVTVNSILGIISVPLSIGYCASKHALRGF 213
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 34.3 bits (75), Expect = 0.37
Identities = 30/106 (28%), Positives = 56/106 (52%), Gaps = 6/106 (5%)
Frame = +1
Query: 277 DVADGDQLAAAYEQVLDKYRRLDGVINNAAV----LSVDER--SFKKMIDINFTATVNST 438
D+ D AA + VL ++ R+D ++NN + L +D ++K+I++N+ TV+ T
Sbjct: 61 DLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLT 120
Query: 439 LKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQF 576
L M I++ + G +V ++S+L + Y A+K A+ F
Sbjct: 121 KCVLPHM-IER--KQGKIVTVNSILGIISVPLSIGYCASKHALRGF 163
>D87717-1|BAA13442.2| 1086|Homo sapiens KIAA0013 protein.
Length = 1086
Score = 33.5 bits (73), Expect = 0.65
Identities = 20/62 (32%), Positives = 32/62 (51%)
Frame = -2
Query: 407 SIIFLKERSSTLKTAALFMTPSSLRYLSKTCSYAAASWSPSATSHFINFALRAPNLFISS 228
SI +ER + L + + +TP++ R L S+ +S + H NF L NLF SS
Sbjct: 367 SITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLFNSS 426
Query: 227 AS 222
++
Sbjct: 427 ST 428
>BC063444-1|AAH63444.1| 501|Homo sapiens Rho GTPase activating
protein 11A protein.
Length = 501
Score = 33.5 bits (73), Expect = 0.65
Identities = 20/62 (32%), Positives = 32/62 (51%)
Frame = -2
Query: 407 SIIFLKERSSTLKTAALFMTPSSLRYLSKTCSYAAASWSPSATSHFINFALRAPNLFISS 228
SI +ER + L + + +TP++ R L S+ +S + H NF L NLF SS
Sbjct: 304 SITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLFNSS 363
Query: 227 AS 222
++
Sbjct: 364 ST 365
>BC039563-1|AAH39563.1| 1023|Homo sapiens Rho GTPase activating
protein 11A protein.
Length = 1023
Score = 33.5 bits (73), Expect = 0.65
Identities = 20/62 (32%), Positives = 32/62 (51%)
Frame = -2
Query: 407 SIIFLKERSSTLKTAALFMTPSSLRYLSKTCSYAAASWSPSATSHFINFALRAPNLFISS 228
SI +ER + L + + +TP++ R L S+ +S + H NF L NLF SS
Sbjct: 304 SITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLFNSS 363
Query: 227 AS 222
++
Sbjct: 364 ST 365
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 32.3 bits (70), Expect = 1.5
Identities = 43/181 (23%), Positives = 75/181 (41%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ M+S R + ++V +VT R L + A HV I+ R+ ++
Sbjct: 21 VRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGA-HVV---ISSRKQQNVDRA 76
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L I C V + + L+ +D ++ +A V L E+
Sbjct: 77 MAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQ 136
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K++ +N + + L M R G V+ +SS+ A NP L VY+ +KTA+
Sbjct: 137 IWDKILSVNVKSPAPLLSQLLPYME----NRRGAVILVSSVAAYNPVVALGVYSVSKTAL 192
Query: 568 L 570
L
Sbjct: 193 L 193
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 31.9 bits (69), Expect = 2.0
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +1
Query: 394 KKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQ 573
KKMI+IN + T L M +++ G ++N+SS + P L +Y+ATKT V
Sbjct: 155 KKMININILSVCKMTQLVLPGM-VERSK--GAILNISSGSGMLPVPLLTIYSATKTFVDF 211
Query: 574 FS 579
FS
Sbjct: 212 FS 213
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 31.9 bits (69), Expect = 2.0
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +1
Query: 394 KKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQ 573
KKMI+IN + T L M +++ G ++N+SS + P L +Y+ATKT V
Sbjct: 155 KKMININILSVCKMTQLVLPGM-VERSK--GAILNISSGSGMLPVPLLTIYSATKTFVDF 211
Query: 574 FS 579
FS
Sbjct: 212 FS 213
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 31.9 bits (69), Expect = 2.0
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +1
Query: 394 KKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAVLQ 573
KKMI+IN + T L M +++ G ++N+SS + P L +Y+ATKT V
Sbjct: 20 KKMININILSVCKMTQLVLPGM-VERSK--GAILNISSGSGMLPVPLLTIYSATKTFVDF 76
Query: 574 FS 579
FS
Sbjct: 77 FS 78
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 31.1 bits (67), Expect = 3.4
Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ M+S R + ++V +VT R L + A HV I+ R+ ++
Sbjct: 21 VRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGA-HVV---ISSRKQQNVDRA 76
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L I C V + + L+ +D ++ +A V L E+
Sbjct: 77 MAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQ 136
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K++ +N + + L M R G V+ +SS+ A NP L VY +KTA+
Sbjct: 137 IWDKILSVNVKSPALLLSQLLPYME----NRRGAVILVSSIAAYNPVVALGVYNVSKTAL 192
Query: 568 L 570
L
Sbjct: 193 L 193
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 31.1 bits (67), Expect = 3.4
Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ M+S R + ++V +VT R L + A HV I+ R+ ++
Sbjct: 12 VRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGA-HVV---ISSRKQQNVDRA 67
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L I C V + + L+ +D ++ +A V L E+
Sbjct: 68 MAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQ 127
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K++ +N + + L M R G V+ +SS+ A NP L VY +KTA+
Sbjct: 128 IWDKILSVNVKSPALLLSQLLPYME----NRRGAVILVSSIAAYNPVVALGVYNVSKTAL 183
Query: 568 L 570
L
Sbjct: 184 L 184
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 31.1 bits (67), Expect = 3.4
Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ M+S R + ++V +VT R L + A HV I+ R+ ++
Sbjct: 21 VRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGA-HVV---ISSRKQQNVDRA 76
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L I C V + + L+ +D ++ +A V L E+
Sbjct: 77 MAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQ 136
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K++ +N + + L M R G V+ +SS+ A NP L VY +KTA+
Sbjct: 137 IWDKILSVNVKSPALLLSQLLPYME----NRRGAVILVSSIAAYNPVVALGVYNVSKTAL 192
Query: 568 L 570
L
Sbjct: 193 L 193
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 31.1 bits (67), Expect = 3.4
Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 8/181 (4%)
Frame = +1
Query: 52 LNMASNFGKRSVNIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAE 231
+ M+S R + ++V +VT R L + A HV I+ R+ ++
Sbjct: 21 VRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGA-HVV---ISSRKQQNVDRA 76
Query: 232 LINKFG-ALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAV-------LSVDER 387
+ G L I C V + + L+ +D ++ +A V L E+
Sbjct: 77 MAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQ 136
Query: 388 SFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTAV 567
+ K++ +N + + L M R G V+ +SS+ A NP L VY +KTA+
Sbjct: 137 IWDKILSVNVKSPALLLSQLLPYME----NRRGAVILVSSIAAYNPVVALGVYNVSKTAL 192
Query: 568 L 570
L
Sbjct: 193 L 193
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 30.7 bits (66), Expect = 4.6
Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 7/131 (5%)
Frame = +1
Query: 226 AELINKFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAA--VLSVDER---- 387
AE I+ + I+CDV D D + +++ + VINNAA +S ER
Sbjct: 100 AEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN 159
Query: 388 SFKKMIDINFTATVNSTLK-GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTA 564
++K + DI T TL+ G + K +G ++++++ A S + A+ K
Sbjct: 160 AWKTITDIVLNGTAFVTLEIGKQLI---KAQKGAAFLSITTIYAETGSGFVVPSASAKAG 216
Query: 565 VLQFSIAMGSD 597
V S ++ ++
Sbjct: 217 VEAMSKSLAAE 227
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 30.7 bits (66), Expect = 4.6
Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 7/131 (5%)
Frame = +1
Query: 226 AELINKFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAA--VLSVDER---- 387
AE I+ + I+CDV D D + +++ + VINNAA +S ER
Sbjct: 100 AEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN 159
Query: 388 SFKKMIDINFTATVNSTLK-GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTA 564
++K + DI T TL+ G + K +G ++++++ A S + A+ K
Sbjct: 160 AWKTITDIVLNGTAFVTLEIGKQLI---KAQKGAAFLSITTIYAETGSGFVVPSASAKAG 216
Query: 565 VLQFSIAMGSD 597
V S ++ ++
Sbjct: 217 VEAMSKSLAAE 227
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 30.7 bits (66), Expect = 4.6
Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 7/131 (5%)
Frame = +1
Query: 226 AELINKFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAA--VLSVDER---- 387
AE I+ + I+CDV D D + +++ + VINNAA +S ER
Sbjct: 100 AEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN 159
Query: 388 SFKKMIDINFTATVNSTLK-GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTA 564
++K + DI T TL+ G + K +G ++++++ A S + A+ K
Sbjct: 160 AWKTITDIVLNGTAFVTLEIGKQLI---KAQKGAAFLSITTIYAETGSGFVVPSASAKAG 216
Query: 565 VLQFSIAMGSD 597
V S ++ ++
Sbjct: 217 VEAMSKSLAAE 227
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 30.7 bits (66), Expect = 4.6
Identities = 23/63 (36%), Positives = 32/63 (50%)
Frame = +1
Query: 382 ERSFKKMIDINFTATVNSTLKGLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKT 561
ER +DIN A T + M +K G G VV+ +SS+ A +PS Y +KT
Sbjct: 97 ERLVATTLDINVKAPALMTKAVVPEM--EKRGGGSVVI-VSSIAAFSPSPGFSPYNVSKT 153
Query: 562 AVL 570
A+L
Sbjct: 154 ALL 156
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 30.7 bits (66), Expect = 4.6
Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 7/131 (5%)
Frame = +1
Query: 226 AELINKFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAA--VLSVDER---- 387
AE I+ + I+CDV D D + +++ + VINNAA +S ER
Sbjct: 100 AEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN 159
Query: 388 SFKKMIDINFTATVNSTLK-GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTA 564
++K + DI T TL+ G + K +G ++++++ A S + A+ K
Sbjct: 160 AWKTITDIVLNGTAFVTLEIGKQLI---KAQKGAAFLSITTIYAETGSGFVVPSASAKAG 216
Query: 565 VLQFSIAMGSD 597
V S ++ ++
Sbjct: 217 VEAMSKSLAAE 227
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 30.7 bits (66), Expect = 4.6
Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 7/131 (5%)
Frame = +1
Query: 226 AELINKFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAA--VLSVDER---- 387
AE I+ + I+CDV D D + +++ + VINNAA +S ER
Sbjct: 100 AEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN 159
Query: 388 SFKKMIDINFTATVNSTLK-GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTA 564
++K + DI T TL+ G + K +G ++++++ A S + A+ K
Sbjct: 160 AWKTITDIVLNGTAFVTLEIGKQLI---KAQKGAAFLSITTIYAETGSGFVVPSASAKAG 216
Query: 565 VLQFSIAMGSD 597
V S ++ ++
Sbjct: 217 VEAMSKSLAAE 227
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 30.7 bits (66), Expect = 4.6
Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 7/131 (5%)
Frame = +1
Query: 226 AELINKFGALRAKFIKCDVADGDQLAAAYEQVLDKYRRLDGVINNAA--VLSVDER---- 387
AE I+ + I+CDV D D + +++ + VINNAA +S ER
Sbjct: 100 AEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN 159
Query: 388 SFKKMIDINFTATVNSTLK-GLDCMGIDKGGRGGVVVNMSSLLALNPSSHLPVYAATKTA 564
++K + DI T TL+ G + K +G ++++++ A S + A+ K
Sbjct: 160 AWKTITDIVLNGTAFVTLEIGKQLI---KAQKGAAFLSITTIYAETGSGFVVPSASAKAG 216
Query: 565 VLQFSIAMGSD 597
V S ++ ++
Sbjct: 217 VEAMSKSLAAE 227
>Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 169
Score = 30.3 bits (65), Expect = 6.0
Identities = 35/158 (22%), Positives = 61/158 (38%), Gaps = 15/158 (9%)
Frame = +1
Query: 88 NIEDKVFLVTXXXXXXXXXXXRALLSENARHVAFLDIAVREGAALEAELINKFGALRAKF 267
+++ V ++T L+ + A V LD+ G A +L N F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKLGNN-----CVF 60
Query: 268 IKCDVADGDQLAAAYEQVLDKYRRLDGVINNAAVLSVDE------------RSFKKMIDI 411
DV + A K+ R+D +N A + + F++++D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 412 NFTATVNSTLKGLDCMGI---DKGGRGGVVVNMSSLLA 516
N T N MG D+GG+ GV++N +S+ A
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA 158
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 79,641,046
Number of Sequences: 237096
Number of extensions: 1496168
Number of successful extensions: 2978
Number of sequences better than 10.0: 66
Number of HSP's better than 10.0 without gapping: 2866
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2965
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7028963750
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -