Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0001_A14
(545 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q402E3 Cluster: Ebony; n=4; Neoptera|Rep: Ebony - Papil... 254 1e-66
UniRef50_Q9GSP4 Cluster: Mutant e4 ebony; n=2; Drosophila|Rep: M... 200 1e-50
UniRef50_O76858 Cluster: Ebony protein; n=18; Diptera|Rep: Ebony... 200 1e-50
UniRef50_UPI0000DB6BFA Cluster: PREDICTED: similar to ebony CG33... 168 6e-41
UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2; Cyanobacte... 124 1e-27
UniRef50_Q08787 Cluster: Surfactin synthetase subunit 3; n=9; Ba... 124 1e-27
UniRef50_Q0LPK1 Cluster: Amino acid adenylation; n=1; Herpetosip... 121 9e-27
UniRef50_A1KQR7 Cluster: RhiB protein; n=1; Burkholderia rhizoxi... 121 9e-27
UniRef50_Q8VQF9 Cluster: Peptide synthetase XpsA; n=1; Xenorhabd... 120 2e-26
UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular... 119 4e-26
UniRef50_Q8VQF8 Cluster: Peptide synthetase XpsB; n=1; Xenorhabd... 119 4e-26
UniRef50_Q4C3C2 Cluster: Amino acid adenylation; n=1; Crocosphae... 119 4e-26
UniRef50_Q0B1F6 Cluster: Amino acid adenylation domain; n=2; Bac... 119 4e-26
UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibio... 118 7e-26
UniRef50_Q2N3S9 Cluster: Hybrid nonribosomal peptide synthetase/... 118 7e-26
UniRef50_Q84BC8 Cluster: NcpA; n=5; Cyanobacteria|Rep: NcpA - No... 118 9e-26
UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3; ... 117 2e-25
UniRef50_Q0LIS9 Cluster: Amino acid adenylation; n=1; Herpetosip... 117 2e-25
UniRef50_Q4KCD8 Cluster: Nonribosomal peptide synthase; n=2; cel... 116 3e-25
UniRef50_Q1DBW4 Cluster: Non-ribosomal peptide synthetase; n=3; ... 116 3e-25
UniRef50_O68006 Cluster: Bacitracin synthetase 1 (BA1) [Includes... 116 3e-25
UniRef50_Q2VQ15 Cluster: Nonribosomal peptide synthetase C; n=3;... 116 4e-25
UniRef50_Q4ZT67 Cluster: Amino acid adenylation; n=15; Bacteria|... 116 5e-25
UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 116 5e-25
UniRef50_UPI000038CB2F Cluster: COG1020: Non-ribosomal peptide s... 115 6e-25
UniRef50_Q93H59 Cluster: Non-ribosimal peptide synthetase; n=1; ... 115 6e-25
UniRef50_Q7N7D0 Cluster: Complete genome; segment 5/17; n=1; Pho... 115 6e-25
UniRef50_Q3M5N4 Cluster: Amino acid adenylation; n=1; Anabaena v... 115 6e-25
UniRef50_Q93N89 Cluster: Peptide synthetase; n=1; Streptomyces l... 115 6e-25
UniRef50_Q4C3C3 Cluster: Non-ribosomal peptide synthase:Amino ac... 115 6e-25
UniRef50_Q1D6A0 Cluster: Non-ribosomal peptide synthetase; n=7; ... 115 6e-25
UniRef50_Q0SKF6 Cluster: Non-ribosomal peptide synthetase; n=2; ... 115 6e-25
UniRef50_A7BXM0 Cluster: Non-ribosomal peptide synthetase; n=2; ... 115 6e-25
UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine syn... 115 6e-25
UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C ... 115 6e-25
UniRef50_Q83DF1 Cluster: Peptide synthetase, putative; n=6; Coxi... 115 8e-25
UniRef50_Q70C47 Cluster: Polyketide non-ribosomal peptide syntha... 115 8e-25
UniRef50_Q2VQ13 Cluster: Nonribosomal peptide synthetase E; n=1;... 115 8e-25
UniRef50_Q8L334 Cluster: Peptide synthetase; n=14; Nostocaceae|R... 114 1e-24
UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2; Bac... 114 1e-24
UniRef50_A5N8Z4 Cluster: Predicted hybrid nonribosomal peptide s... 114 1e-24
UniRef50_A3YFF7 Cluster: Amino acid adenylation; n=1; Marinomona... 114 1e-24
UniRef50_A3INW9 Cluster: Amino acid adenylation; n=1; Cyanothece... 114 1e-24
UniRef50_A7T272 Cluster: Predicted protein; n=1; Nematostella ve... 114 1e-24
UniRef50_A0UUS4 Cluster: Amino acid adenylation domain; n=1; Clo... 114 1e-24
UniRef50_O31782 Cluster: Polyketide synthase of type I; n=2; Bac... 113 2e-24
UniRef50_A5FI48 Cluster: Amino acid adenylation domain; n=2; cel... 113 2e-24
UniRef50_A3INW8 Cluster: Peptide synthetase; n=3; Chroococcales|... 113 2e-24
UniRef50_Q4KES9 Cluster: Nonribosomal peptide synthetase; n=6; B... 113 3e-24
UniRef50_Q4ZT69 Cluster: Amino acid adenylation; n=8; cellular o... 113 3e-24
UniRef50_A7IZW1 Cluster: OciA; n=1; Planktothrix agardhii NIVA-C... 113 3e-24
UniRef50_A0ZF79 Cluster: Non-ribosomal peptide synthase; n=6; Cy... 113 3e-24
UniRef50_Q0AY10 Cluster: Non-ribosomal peptide synthetase module... 112 4e-24
UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC 71... 112 6e-24
UniRef50_Q333V5 Cluster: NRPS protein; n=2; Actinomycetales|Rep:... 112 6e-24
UniRef50_Q18BS4 Cluster: Putative nonribosomal peptide synthetas... 112 6e-24
UniRef50_Q0RI59 Cluster: Non-ribosomal peptide synthetase; n=3; ... 112 6e-24
UniRef50_Q08MM0 Cluster: Linear gramicidin synthetase subunit B;... 112 6e-24
UniRef50_A0UVH5 Cluster: Amino acid adenylation domain; n=2; Bac... 112 6e-24
UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep... 112 6e-24
UniRef50_Q3M5M7 Cluster: Amino acid adenylation; n=1; Anabaena v... 111 8e-24
UniRef50_O07944 Cluster: Pristinamycin I synthase 3 and 4; n=2; ... 111 8e-24
UniRef50_A6ASZ6 Cluster: Enterobactin synthetase component F; n=... 111 8e-24
UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1;... 111 1e-23
UniRef50_A3KFG5 Cluster: PstC protein; n=2; Actinomycetales|Rep:... 111 1e-23
UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1; Alca... 111 1e-23
UniRef50_UPI000038DECD Cluster: COG1020: Non-ribosomal peptide s... 110 2e-23
UniRef50_Q93N87 Cluster: Peptide synthetase; n=12; Bacteria|Rep:... 110 2e-23
UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide synthetase/polyke... 110 2e-23
UniRef50_A4PHL4 Cluster: Non ribosomal peptide synthetase for vi... 110 2e-23
UniRef50_Q8PKR8 Cluster: ATP-dependent serine activating enzyme;... 110 2e-23
UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3; ... 110 2e-23
UniRef50_Q5Z1T0 Cluster: Putative non-ribosomal peptide syntheta... 110 2e-23
UniRef50_Q2ANW8 Cluster: Non-ribosomal peptide synthase:Amino ac... 110 2e-23
UniRef50_UPI000038CDA7 Cluster: COG1020: Non-ribosomal peptide s... 109 3e-23
UniRef50_Q5YPH7 Cluster: Putative non-ribosomal peptide syntheta... 109 3e-23
UniRef50_Q3M3K1 Cluster: Amino acid adenylation precursor; n=2; ... 109 3e-23
UniRef50_Q1RS73 Cluster: NRPS/PKS protein; n=5; Bacteria|Rep: NR... 109 3e-23
UniRef50_Q0LLT6 Cluster: Amino acid adenylation; n=1; Herpetosip... 109 3e-23
UniRef50_A3DGP7 Cluster: Amino acid adenylation domain; n=1; Clo... 109 3e-23
UniRef50_Q3M1N0 Cluster: Amino acid adenylation; n=2; Bacteria|R... 109 4e-23
UniRef50_Q2SKF9 Cluster: Non-ribosomal peptide synthetase module... 109 4e-23
UniRef50_Q04747 Cluster: Surfactin synthetase subunit 2; n=9; Ba... 109 4e-23
UniRef50_O68008 Cluster: Bacitracin synthetase 3 (BA3) [Includes... 109 4e-23
UniRef50_Q84DH9 Cluster: Peptide synthase; n=3; Streptomyces|Rep... 109 5e-23
UniRef50_Q1RS70 Cluster: Hybrid NRPS/PKS; n=4; cellular organism... 109 5e-23
UniRef50_A0ZL90 Cluster: Non-ribosomal peptide synthase; n=1; No... 109 5e-23
UniRef50_Q8GN23 Cluster: Peptide synthetase; n=1; Fischerella sp... 108 7e-23
UniRef50_Q84BC7 Cluster: NcpB; n=3; Cyanobacteria|Rep: NcpB - No... 108 7e-23
UniRef50_Q333U8 Cluster: NRPS protein; n=1; Micromonospora sp. M... 108 7e-23
UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosip... 108 7e-23
UniRef50_A3IZW4 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 108 7e-23
UniRef50_A0PTU8 Cluster: Non-ribosomal peptide synthetase MbtE; ... 108 7e-23
UniRef50_O30409 Cluster: Tyrocidine synthetase 3 (Tyrocidine syn... 108 7e-23
UniRef50_Q93H68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 108 9e-23
UniRef50_Q87WM7 Cluster: Non-ribosomal peptide synthetase, termi... 108 9e-23
UniRef50_Q5ZTI3 Cluster: Peptide synthetase, non-ribosomal; n=2;... 108 9e-23
UniRef50_A6E8C1 Cluster: Amino acid adenylation; n=1; Pedobacter... 108 9e-23
UniRef50_A3WXS1 Cluster: Probable non-ribosomal peptide syntheta... 108 9e-23
UniRef50_A0ZF81 Cluster: Amino acid adenylation protein; n=3; Ba... 108 9e-23
UniRef50_P27206 Cluster: Surfactin synthetase subunit 1; n=15; B... 108 9e-23
UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomona... 107 1e-22
UniRef50_Q1D3K4 Cluster: Non-ribosomal peptide synthase; n=2; My... 107 1e-22
UniRef50_Q0RMQ5 Cluster: Putative non-ribosomal peptide syntheta... 107 1e-22
UniRef50_A5IDB4 Cluster: Peptide synthetase; n=4; Legionella pne... 107 1e-22
UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5; roo... 107 1e-22
UniRef50_Q5JCL8 Cluster: Putative non-ribosomal peptide syntheta... 107 2e-22
UniRef50_Q1D3K7 Cluster: Non-ribosomal peptide synthase; n=1; My... 107 2e-22
UniRef50_Q08XI8 Cluster: Beta-lactamase, putative; n=3; Bacteria... 107 2e-22
UniRef50_A4PHM3 Cluster: Hybrid non ribosomal peptide synthetase... 107 2e-22
UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1; Clo... 107 2e-22
UniRef50_Q881Q3 Cluster: Non-ribosomal peptide synthetase, termi... 107 2e-22
UniRef50_Q2Y7Z5 Cluster: Amino acid adenylation; n=2; Nitrosospi... 107 2e-22
UniRef50_Q50857 Cluster: Saframycin Mx1 synthetase B; n=1; Myxoc... 107 2e-22
UniRef50_A4C379 Cluster: Non-ribosomal peptide synthetase, termi... 107 2e-22
UniRef50_P45745 Cluster: Dimodular nonribosomal peptide syntheta... 107 2e-22
UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces... 106 3e-22
UniRef50_Q0S1Z9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 106 3e-22
UniRef50_A5FI40 Cluster: Amino acid adenylation domain; n=1; Fla... 106 3e-22
UniRef50_A3DGP4 Cluster: Amino acid adenylation domain; n=1; Clo... 106 3e-22
UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular orga... 106 4e-22
UniRef50_Q4C9F4 Cluster: Non-ribosomal peptide synthase:Amino ac... 106 4e-22
UniRef50_Q1D3L3 Cluster: Non-ribosomal peptide synthase; n=1; My... 106 4e-22
UniRef50_Q0PH94 Cluster: MassC; n=1; Pseudomonas fluorescens|Rep... 106 4e-22
UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin s... 106 4e-22
UniRef50_A3I9A7 Cluster: Peptide synthetase; n=1; Bacillus sp. B... 106 4e-22
UniRef50_Q83Z53 Cluster: Putisolvin synthetase; n=3; Bacteria|Re... 105 5e-22
UniRef50_Q70P97 Cluster: MelC protein; n=4; Cystobacteraceae|Rep... 105 5e-22
UniRef50_A4JPB0 Cluster: Amino acid adenylation domain; n=1; Bur... 105 5e-22
UniRef50_A4FE18 Cluster: Non-ribosomal peptide synthetase; n=3; ... 105 5e-22
UniRef50_A4BRH4 Cluster: Probable peptide synthetase protein; n=... 105 5e-22
UniRef50_A1ZSC1 Cluster: Mixed type I polyketide synthase-peptid... 105 5e-22
UniRef50_A1G2S8 Cluster: Amino acid adenylation domain; n=1; Sal... 105 5e-22
UniRef50_P40806 Cluster: Putative polyketide synthase pksJ; n=9;... 105 5e-22
UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1; ... 105 7e-22
UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Re... 105 7e-22
UniRef50_Q70C52 Cluster: Non-ribosomal peptide synthase; n=1; Xa... 105 7e-22
UniRef50_Q6YK39 Cluster: Bacillomycin D synthetase C; n=4; Bacil... 105 7e-22
UniRef50_Q4U445 Cluster: DszC; n=3; Proteobacteria|Rep: DszC - P... 105 7e-22
UniRef50_Q44103 Cluster: Peptide-synthetase; n=1; Amycolatopsis ... 105 7e-22
UniRef50_A7BRU4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 105 7e-22
UniRef50_A4CG27 Cluster: Amino acid adenylation; n=2; Pseudoalte... 105 7e-22
UniRef50_A0YGI5 Cluster: Peptide synthetase; n=1; marine gamma p... 105 7e-22
UniRef50_A0UVJ0 Cluster: Amino acid adenylation domain; n=2; Clo... 105 7e-22
UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide syntheta... 105 9e-22
UniRef50_Q89T13 Cluster: Bll2237 protein; n=2; Bradyrhizobium|Re... 105 9e-22
UniRef50_Q4ZV19 Cluster: Non-ribosomal peptide synthase:Amino ac... 105 9e-22
UniRef50_Q2JA66 Cluster: Amino acid adenylation; n=15; Bacteria|... 105 9e-22
UniRef50_Q2JA64 Cluster: Amino acid adenylation; n=3; Actinomyce... 105 9e-22
UniRef50_Q0SEB1 Cluster: Non-ribosomal peptide synthetase; n=2; ... 105 9e-22
UniRef50_Q9RFK5 Cluster: MtaG; n=4; Cystobacteraceae|Rep: MtaG -... 105 9e-22
UniRef50_Q847C8 Cluster: NdaB; n=32; Cyanobacteria|Rep: NdaB - N... 105 9e-22
UniRef50_Q4CA71 Cluster: Amino acid adenylation; n=1; Crocosphae... 105 9e-22
UniRef50_Q211M6 Cluster: Amino acid adenylation; n=1; Rhodopseud... 105 9e-22
UniRef50_Q0B1F5 Cluster: Amino acid adenylation domain; n=1; Bur... 105 9e-22
UniRef50_Q08MR4 Cluster: Linear gramicidin synthetase subunit D;... 105 9e-22
UniRef50_A6LQ10 Cluster: Amino acid adenylation domain; n=1; Clo... 105 9e-22
UniRef50_A1G7W6 Cluster: Amino acid adenylation domain; n=2; Sal... 105 9e-22
UniRef50_UPI000045C11E Cluster: COG1020: Non-ribosomal peptide s... 104 1e-21
UniRef50_Q2SHZ4 Cluster: Non-ribosomal peptide synthetase module... 104 1e-21
UniRef50_Q0PH95 Cluster: MassB; n=2; Pseudomonas fluorescens|Rep... 104 1e-21
UniRef50_Q0LP44 Cluster: Amino acid adenylation; n=1; Herpetosip... 104 1e-21
UniRef50_A6YEH8 Cluster: CmnG; n=1; Saccharothrix mutabilis subs... 104 1e-21
UniRef50_A4FCX9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 104 1e-21
UniRef50_A3IP47 Cluster: Peptide synthetase; n=2; Cyanobacteria|... 104 1e-21
UniRef50_UPI000045BE69 Cluster: COG1020: Non-ribosomal peptide s... 104 2e-21
UniRef50_Q0SE34 Cluster: Non-ribosomal peptide synthetase; n=1; ... 104 2e-21
UniRef50_A4F3K7 Cluster: Non-ribosomal peptide synthetase; n=3; ... 104 2e-21
UniRef50_Q2SFM4 Cluster: Non-ribosomal peptide synthetase module... 103 2e-21
UniRef50_Q6E7J8 Cluster: JamL; n=4; Bacteria|Rep: JamL - Lyngbya... 103 2e-21
UniRef50_Q5MP00 Cluster: OnnI; n=1; symbiont bacterium of Theone... 103 2e-21
UniRef50_Q3WDU5 Cluster: Amino acid adenylation; n=1; Frankia sp... 103 2e-21
UniRef50_Q1D6B8 Cluster: Non-ribosomal peptide synthetase; n=5; ... 103 2e-21
UniRef50_Q1D3K9 Cluster: Non-ribosomal peptide synthase; n=1; My... 103 2e-21
UniRef50_O87314 Cluster: FxbC; n=5; Mycobacterium smegmatis|Rep:... 103 2e-21
UniRef50_A3HT12 Cluster: Non-ribosomal peptide synthase; n=1; Al... 103 2e-21
UniRef50_A0ZL89 Cluster: Non-ribosomal peptide synthase; n=1; No... 103 2e-21
UniRef50_Q8CJX2 Cluster: CDA peptide synthetase III; n=3; Strept... 103 3e-21
UniRef50_Q7N3S1 Cluster: Complete genome; segment 9/17; n=1; Pho... 103 3e-21
UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4; Ph... 103 3e-21
UniRef50_Q20CI8 Cluster: CesB; n=7; cellular organisms|Rep: CesB... 103 3e-21
UniRef50_Q1IA18 Cluster: Putative non-ribosomal peptide syntheta... 103 3e-21
UniRef50_Q0K0K4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 103 3e-21
UniRef50_Q08N46 Cluster: Condensation domain protein; n=3; Stigm... 103 3e-21
UniRef50_A0NTU6 Cluster: Putative non-ribosomal peptide syntheta... 103 3e-21
UniRef50_UPI00005F995E Cluster: COG1020: Non-ribosomal peptide s... 103 4e-21
UniRef50_Q9F9L4 Cluster: Micrococcin P1 peptide synthetase; n=1;... 103 4e-21
UniRef50_Q70AZ6 Cluster: Non-ribosomal peptide synthetase; n=6; ... 103 4e-21
UniRef50_Q0S7I5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 103 4e-21
UniRef50_A7IZW2 Cluster: OciB; n=1; Planktothrix agardhii NIVA-C... 103 4e-21
UniRef50_A4KVL5 Cluster: Non-ribosomal peptide synthetase module... 103 4e-21
UniRef50_A3KFG6 Cluster: PstD protein; n=1; Actinoplanes friulie... 103 4e-21
UniRef50_A0ZF82 Cluster: Non-ribosomal peptide synthase; n=2; No... 103 4e-21
UniRef50_Q8YTR5 Cluster: Peptide synthetase; n=7; Cyanobacteria|... 102 5e-21
UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7; Pseudomona... 102 5e-21
UniRef50_Q9K5M1 Cluster: Peptide synthetase; n=8; Bacteria|Rep: ... 102 5e-21
UniRef50_Q6HXY8 Cluster: AMP-binding enzyme; n=10; Bacillus cere... 102 5e-21
UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces... 102 5e-21
UniRef50_Q0YRD8 Cluster: Amino acid adenylation; n=2; cellular o... 102 5e-21
UniRef50_A0V6U0 Cluster: Amino acid adenylation domain; n=1; Del... 102 5e-21
UniRef50_Q2SW14 Cluster: Peptide synthetase, putative; n=1; Burk... 102 6e-21
UniRef50_Q7BQ70 Cluster: Putative peptide synthetase/polyketide ... 102 6e-21
UniRef50_Q70JX4 Cluster: FenD protein; n=18; Bacillus|Rep: FenD ... 102 6e-21
UniRef50_Q0YRE2 Cluster: Amino acid adenylation; n=1; Chlorobium... 102 6e-21
UniRef50_Q0LKI8 Cluster: Amino acid adenylation; n=1; Herpetosip... 102 6e-21
UniRef50_A3IZB3 Cluster: Amino acid adenylation; n=2; Chroococca... 102 6e-21
UniRef50_A0UXC9 Cluster: Amino acid adenylation domain; n=2; Bac... 102 6e-21
UniRef50_A0JZK7 Cluster: Amino acid adenylation domain; n=1; Art... 102 6e-21
UniRef50_Q8YTR8 Cluster: Peptide synthetase; n=2; Nostocaceae|Re... 101 8e-21
UniRef50_Q8CQA8 Cluster: Surfactin synthetase; n=14; Staphylococ... 101 8e-21
UniRef50_Q63CQ6 Cluster: Multifunctional nonribosomal peptide sy... 101 8e-21
UniRef50_Q63CQ5 Cluster: Multifunctional nonribosomal peptide sy... 101 8e-21
UniRef50_Q9Z5F4 Cluster: Ta1; n=4; Bacteria|Rep: Ta1 - Myxococcu... 101 8e-21
UniRef50_Q2ANX0 Cluster: Non-ribosomal peptide synthase:Amino ac... 101 8e-21
UniRef50_Q1D8L0 Cluster: Non-ribosomal peptide synthetase; n=1; ... 101 8e-21
UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1; My... 101 8e-21
UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8; Ba... 101 8e-21
UniRef50_Q0VZ70 Cluster: Non ribosomal peptide synthase; n=1; Ch... 101 8e-21
UniRef50_A7BKL9 Cluster: Non-ribosomal peptide synthetase; n=2; ... 101 8e-21
UniRef50_A5W120 Cluster: Amino acid adenylation domain; n=3; Bac... 101 8e-21
UniRef50_A5EHY7 Cluster: Non ribosomal peptide synthase; n=1; Br... 101 8e-21
UniRef50_A3YGI9 Cluster: Amino acid adenylation; n=1; Marinomona... 101 8e-21
UniRef50_Q88JT4 Cluster: Antibiotic biosynthesis protein, putati... 101 1e-20
UniRef50_Q6VT95 Cluster: Mixed type I polyketide synthase/nonrib... 101 1e-20
UniRef50_Q1D3T0 Cluster: Non-ribosomal peptide synthase MxaA; n=... 101 1e-20
UniRef50_Q0SKF9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 101 1e-20
UniRef50_A6P624 Cluster: Nonribosomal peptide synthetase; n=1; M... 101 1e-20
UniRef50_A4FEM4 Cluster: Non-ribosomal peptide synthetase module... 101 1e-20
UniRef50_A0UXD5 Cluster: Amino acid adenylation domain; n=1; Clo... 101 1e-20
UniRef50_UPI00015978D8 Cluster: NrsC; n=1; Bacillus amyloliquefa... 101 1e-20
UniRef50_Q3M3K2 Cluster: Amino acid adenylation; n=2; Nostocacea... 101 1e-20
UniRef50_Q6WZB2 Cluster: Nonribosomal peptide synthetase; n=1; S... 101 1e-20
UniRef50_Q5J1Q7 Cluster: NocA; n=1; Nocardia uniformis subsp. ts... 101 1e-20
UniRef50_Q1IBI9 Cluster: Putative non-ribosomal peptide syntheta... 101 1e-20
UniRef50_Q1DCS5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 101 1e-20
UniRef50_Q1D593 Cluster: Non-ribosomal peptide synthetase; n=4; ... 101 1e-20
UniRef50_Q0S6F2 Cluster: Non-ribosomal peptide synthetase; n=2; ... 101 1e-20
UniRef50_A5FI38 Cluster: Amino acid adenylation domain; n=2; Bac... 101 1e-20
UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide syntheta... 101 1e-20
UniRef50_A0V6U3 Cluster: Amino acid adenylation domain; n=1; Del... 101 1e-20
UniRef50_Q5YPH6 Cluster: Putative non-ribosomal peptide syntheta... 100 2e-20
UniRef50_Q47NR9 Cluster: Non-ribosomal peptide synthase:Amino ac... 100 2e-20
UniRef50_Q5IW58 Cluster: Phosphinothricin tripeptide synthetase ... 100 2e-20
UniRef50_Q5DIV7 Cluster: PvdI; n=5; Pseudomonas aeruginosa|Rep: ... 100 2e-20
UniRef50_Q4H1C8 Cluster: Non-ribosomal peptide synthetase B; n=1... 100 2e-20
UniRef50_A5YBV1 Cluster: Fusaricidin synthetase; n=1; Paenibacil... 100 2e-20
UniRef50_Q8YTR9 Cluster: Peptide synthetase; n=2; Nostocaceae|Re... 100 3e-20
UniRef50_Q4ZVI3 Cluster: Amino acid adenylation; n=3; Pseudomona... 100 3e-20
UniRef50_Q311J0 Cluster: Amino acid adenylation; n=2; Bacteria|R... 100 3e-20
UniRef50_Q9FB27 Cluster: Peptide synthetase NRPS9-8; n=2; Actino... 100 3e-20
UniRef50_Q5DIP4 Cluster: PvdJ; n=19; root|Rep: PvdJ - Pseudomona... 100 3e-20
UniRef50_Q216S9 Cluster: Amino acid adenylation; n=1; Rhodopseud... 100 3e-20
UniRef50_Q0LLQ8 Cluster: Amino acid adenylation; n=2; Herpetosip... 100 3e-20
UniRef50_Q094I7 Cluster: Aminotransferase, class III family; n=9... 100 3e-20
UniRef50_A6VYF8 Cluster: Amino acid adenylation domain; n=1; Mar... 100 3e-20
UniRef50_A0UVH3 Cluster: Amino acid adenylation domain; n=1; Clo... 100 3e-20
UniRef50_Q2UIN6 Cluster: Non-ribosomal peptide synthetase module... 100 3e-20
UniRef50_UPI00005F935B Cluster: COG1020: Non-ribosomal peptide s... 99 3e-20
UniRef50_Q87WM8 Cluster: Non-ribosomal peptide synthetase, initi... 99 3e-20
UniRef50_Q3JS97 Cluster: Unnamed protein product; n=10; Burkhold... 99 3e-20
UniRef50_O31827 Cluster: Plipastatin synthetase; n=7; Bacillus|R... 99 3e-20
UniRef50_Q643C7 Cluster: Mannopeptimycin peptide synthetase MppA... 99 3e-20
UniRef50_Q4CA68 Cluster: Amino acid adenylation; n=1; Crocosphae... 99 3e-20
UniRef50_O69146 Cluster: Peptide synthetase; n=1; Bacillus subti... 99 3e-20
UniRef50_A5MZS0 Cluster: Predicted nonribosomal peptide syntheta... 99 3e-20
UniRef50_A1G504 Cluster: Amino acid adenylation domain; n=1; Sal... 99 3e-20
UniRef50_A1FGJ0 Cluster: Amino acid adenylation; n=2; cellular o... 99 3e-20
UniRef50_A0V6T7 Cluster: Amino acid adenylation domain; n=2; Com... 99 3e-20
UniRef50_Q9AKS6 Cluster: Siderophore non-ribosomal peptide synth... 100 4e-20
UniRef50_Q93N86 Cluster: Peptide synthetase; n=2; Actinomycetale... 100 4e-20
UniRef50_Q216S7 Cluster: Amino acid adenylation; n=1; Rhodopseud... 100 4e-20
UniRef50_Q1ER08 Cluster: Cereulide synthetase 1; n=6; Bacillus|R... 100 4e-20
UniRef50_Q0LN70 Cluster: Amino acid adenylation; n=1; Herpetosip... 100 4e-20
UniRef50_Q47NS1 Cluster: Amino acid adenylation; n=1; Thermobifi... 99 6e-20
UniRef50_Q3JQV3 Cluster: Nonribosomal peptide synthetase; n=24; ... 99 6e-20
UniRef50_Q5J1Q6 Cluster: NocB; n=1; Nocardia uniformis subsp. ts... 99 6e-20
UniRef50_Q0VZ71 Cluster: Non ribosomal peptide synthase; n=1; Ch... 99 6e-20
UniRef50_Q0MYM1 Cluster: Nonribosomal peptide synthetase; n=2; L... 99 6e-20
UniRef50_A2R200 Cluster: Contig An13c0090, complete genome; n=1;... 99 6e-20
UniRef50_O68007 Cluster: Bacitracin synthetase 2 (BA2) [Includes... 99 6e-20
UniRef50_Q8YTS0 Cluster: Microcystin synthetase B; n=3; Nostocac... 99 8e-20
UniRef50_Q6N4J8 Cluster: Possible McyE polykeitde synthase and p... 99 8e-20
UniRef50_Q8KSQ1 Cluster: Peptide synthetase ScpsA; n=1; Saccharo... 99 8e-20
UniRef50_Q0S3K6 Cluster: Non-ribosomal peptide synthetase; n=2; ... 99 8e-20
UniRef50_A7BWG0 Cluster: Non-ribosomal peptide synthetase; n=2; ... 99 8e-20
UniRef50_A4XD37 Cluster: Amino acid adenylation domain; n=2; Sal... 99 8e-20
UniRef50_A4D936 Cluster: CrpD; n=2; Nostocaceae|Rep: CrpD - Nost... 99 8e-20
UniRef50_A3X327 Cluster: Non-ribosomal siderophore peptide synth... 99 8e-20
UniRef50_Q8YTR4 Cluster: All2649 protein; n=3; Nostocaceae|Rep: ... 98 1e-19
UniRef50_Q7N7D7 Cluster: Similarities with probable non-ribosoma... 98 1e-19
UniRef50_Q2T5X0 Cluster: Peptide synthetase, putative; n=11; pse... 98 1e-19
UniRef50_Q9FB18 Cluster: Peptide synthetase NRPS2-1; n=1; Strept... 98 1e-19
UniRef50_Q8G982 Cluster: Peptide synthetase; n=102; Cyanobacteri... 98 1e-19
UniRef50_Q3WHQ1 Cluster: Non-ribosomal peptide synthase:Amino ac... 98 1e-19
UniRef50_Q0LN68 Cluster: Amino acid adenylation; n=1; Herpetosip... 98 1e-19
UniRef50_A4C382 Cluster: Amino acid adenylation; n=1; Pseudoalte... 98 1e-19
UniRef50_A1FGJ5 Cluster: Amino acid adenylation; n=1; Pseudomona... 98 1e-19
UniRef50_A0Z9R9 Cluster: Putative uncharacterized protein; n=1; ... 98 1e-19
UniRef50_Q5DIU0 Cluster: PvdI; n=3; cellular organisms|Rep: PvdI... 98 1e-19
UniRef50_Q0RMQ8 Cluster: Non-ribosomal peptide synthetase; n=1; ... 98 1e-19
UniRef50_A6V024 Cluster: Amino acid adenylation domain; n=1; Pse... 98 1e-19
UniRef50_Q12HS0 Cluster: Amino acid adenylation; n=1; Shewanella... 97 2e-19
UniRef50_A7IJ33 Cluster: Amino acid adenylation domain; n=1; Xan... 97 2e-19
UniRef50_Q62C03 Cluster: Nonribosomal peptide synthetase DhbF; n... 97 2e-19
UniRef50_Q0LP26 Cluster: Amino acid adenylation; n=1; Herpetosip... 97 2e-19
UniRef50_O52803 Cluster: PCZA361.18; n=3; cellular organisms|Rep... 97 2e-19
UniRef50_A6VYG2 Cluster: Amino acid adenylation domain; n=1; Mar... 97 2e-19
UniRef50_A6EWZ1 Cluster: Peptide synthetase; n=1; Marinobacter a... 97 2e-19
UniRef50_A6E8C2 Cluster: Non-ribosomal peptide synthetase/polyke... 97 2e-19
UniRef50_A4ZPY5 Cluster: DepE; n=2; cellular organisms|Rep: DepE... 97 2e-19
UniRef50_A1EX06 Cluster: Bacitracin synthetase 3; n=1; Coxiella ... 97 2e-19
UniRef50_A0PRJ7 Cluster: Peptide synthetase Nrp; n=1; Mycobacter... 97 2e-19
UniRef50_Q09164 Cluster: Cyclosporine synthetase; n=8; Fungi/Met... 97 2e-19
UniRef50_A1D6D2 Cluster: Nonribosomal peptide synthase GliP2; n=... 97 2e-19
UniRef50_Q68RS4 Cluster: PrnA; n=1; Prochloron didemni|Rep: PrnA... 97 3e-19
UniRef50_Q06YZ2 Cluster: Nonribosomal peptide synthetase; n=1; S... 97 3e-19
UniRef50_A5EJ32 Cluster: Putative non-ribosomal peptide synthase... 97 3e-19
UniRef50_A4ZPY4 Cluster: DepD; n=3; Chromobacterium violaceum|Re... 97 3e-19
UniRef50_A4C380 Cluster: Putative uncharacterized protein; n=1; ... 97 3e-19
UniRef50_A0FCL0 Cluster: MerP; n=2; Streptomyces|Rep: MerP - Str... 97 3e-19
UniRef50_Q2T5Y9 Cluster: Peptide synthetase, putative; n=10; pse... 96 4e-19
UniRef50_Q939Z1 Cluster: Peptide synthetase; n=7; Actinomycetale... 96 4e-19
UniRef50_Q2XNF8 Cluster: Nonribosomal peptide synthetase-polyket... 96 4e-19
UniRef50_Q09E86 Cluster: AMP-binding enzyme domain protein; n=1;... 96 4e-19
UniRef50_A7DBD7 Cluster: Non-ribosomal peptide synthetase; n=4; ... 96 4e-19
UniRef50_A5FI53 Cluster: Amino acid adenylation domain; n=2; Bac... 96 4e-19
UniRef50_A4KVL6 Cluster: Non-ribosomal peptide synthetase module... 96 4e-19
UniRef50_A1ZVW4 Cluster: Linear gramicidin synthetase subunit B;... 96 4e-19
UniRef50_A1EX07 Cluster: Linear gramicidin synthetase subunit C;... 96 4e-19
UniRef50_A1EWJ3 Cluster: Peptide syntetase, degenerate; n=3; Cox... 96 4e-19
UniRef50_A0QH53 Cluster: Linear gramicidin synthetase subunit D;... 96 4e-19
UniRef50_Q93H69 Cluster: Non-ribosomal peptide synthetase; n=1; ... 96 5e-19
UniRef50_Q8KLL4 Cluster: StaB; n=1; Streptomyces toyocaensis|Rep... 96 5e-19
UniRef50_Q840C8 Cluster: Catechol siderophore synthase DhbF-like... 96 5e-19
UniRef50_Q2AZG3 Cluster: Non-ribosomal peptide synthase:Amino ac... 96 5e-19
UniRef50_Q08QA2 Cluster: Linear gramicidin synthetase subunit B;... 96 5e-19
UniRef50_A5EHY6 Cluster: Non-ribosomal peptide synthase; n=2; ce... 96 5e-19
UniRef50_Q93GZ0 Cluster: Non-ribosomal peptide synthetase; n=1; ... 95 7e-19
UniRef50_Q8DTJ7 Cluster: Putative surfactin synthetase; n=1; Str... 95 7e-19
UniRef50_Q7NVV9 Cluster: Synthetase CbsF; n=3; cellular organism... 95 7e-19
UniRef50_Q7N5R5 Cluster: Similar to antibiotic synthetase; n=1; ... 95 7e-19
UniRef50_Q8GGP3 Cluster: Hybrid nonribosomal peptide synthetase ... 95 7e-19
UniRef50_Q7DAG9 Cluster: Peptide synthetase, putative; n=10; Myc... 95 7e-19
UniRef50_Q6E7J5 Cluster: JamO; n=1; Lyngbya majuscula|Rep: JamO ... 95 7e-19
UniRef50_Q45R85 Cluster: Peptide synthetase; n=2; Actinomycetale... 95 7e-19
UniRef50_Q2VQ17 Cluster: Nonribosomal peptide synthetase A; n=1;... 95 7e-19
UniRef50_Q0VNL6 Cluster: Non-ribosomal peptide synthase; n=1; Al... 95 7e-19
UniRef50_A5XI24 Cluster: Non-ribosomal peptide synthase; n=23; B... 95 7e-19
UniRef50_A5P2I4 Cluster: Amino acid adenylation domain; n=6; Alp... 95 7e-19
UniRef50_A4Z4I9 Cluster: McnE; n=5; Cyanobacteria|Rep: McnE - Mi... 95 7e-19
UniRef50_A3N9X4 Cluster: Non-ribosomal peptide synthetase module... 95 7e-19
UniRef50_Q9LAS7 Cluster: Putative uncharacterized protein; n=1; ... 95 9e-19
UniRef50_Q3EYR3 Cluster: Peptide synthetase; n=3; Bacillus cereu... 95 9e-19
UniRef50_A3YGJ0 Cluster: Amino acid adenylation; n=1; Marinomona... 95 9e-19
UniRef50_A3JMY8 Cluster: Non-ribosomal peptide synthetase; n=4; ... 95 9e-19
UniRef50_A2C8M5 Cluster: Putative uncharacterized protein; n=1; ... 95 9e-19
UniRef50_A1TTJ0 Cluster: Amino acid adenylation domain; n=1; Aci... 95 9e-19
UniRef50_A1B557 Cluster: Amino acid adenylation domain; n=2; Pro... 95 9e-19
UniRef50_A5ABE0 Cluster: Contig An11c0010, complete genome; n=1;... 95 9e-19
UniRef50_Q2SGN2 Cluster: Non-ribosomal peptide synthetase module... 95 1e-18
UniRef50_Q6SK65 Cluster: Peptide synthetase; n=5; cellular organ... 95 1e-18
UniRef50_Q5V8A8 Cluster: LtxA; n=1; Lyngbya majuscula|Rep: LtxA ... 95 1e-18
UniRef50_Q3EYD4 Cluster: Peptide synthetase; n=2; Bacillus thuri... 95 1e-18
UniRef50_Q110E8 Cluster: Amino acid adenylation domain; n=1; Tri... 95 1e-18
UniRef50_Q0YRE6 Cluster: Amino acid adenylation; n=1; Chlorobium... 95 1e-18
UniRef50_Q0YRE1 Cluster: Amino acid adenylation; n=1; Chlorobium... 95 1e-18
UniRef50_Q02HM1 Cluster: Putative non-ribosomal peptide syntheta... 95 1e-18
UniRef50_A4X8P7 Cluster: Amino acid adenylation domain; n=1; Sal... 95 1e-18
UniRef50_A1BDX6 Cluster: Amino acid adenylation domain; n=1; Chl... 95 1e-18
UniRef50_A0ZF80 Cluster: Peptide synthetase; n=3; Nostocaceae|Re... 95 1e-18
UniRef50_Q9AMR5 Cluster: ID930; n=1; Bradyrhizobium japonicum|Re... 94 2e-18
UniRef50_Q7D791 Cluster: Peptide synthetase; n=18; Mycobacterium... 94 2e-18
UniRef50_Q50JA3 Cluster: Nonribosomal peptide synthetase; n=2; C... 94 2e-18
UniRef50_Q0K0K6 Cluster: Non-ribosomal peptide synthetase module... 94 2e-18
UniRef50_Q09D72 Cluster: Linear gramicidin synthetase subunit D;... 94 2e-18
UniRef50_P94873 Cluster: Alpha-aminoadipyl-cysteinyl-valine synt... 94 2e-18
UniRef50_A4XWA8 Cluster: Amino acid adenylation domain; n=1; Pse... 94 2e-18
UniRef50_A3YGJ1 Cluster: Amino acid adenylation; n=1; Marinomona... 94 2e-18
UniRef50_A3KI35 Cluster: Putative peptide synthetase; n=1; Strep... 94 2e-18
UniRef50_Q9RK14 Cluster: Putative peptide synthetase; n=1; Strep... 94 2e-18
UniRef50_Q9HYR8 Cluster: Probable non-ribosomal peptide syntheta... 94 2e-18
UniRef50_Q5YVZ9 Cluster: Putative non-ribosomal peptide syntheta... 94 2e-18
UniRef50_Q2T5W7 Cluster: Nonribosomal peptide synthetase, putati... 94 2e-18
UniRef50_Q9L8H4 Cluster: Actinomycin synthetase III; n=1; Strept... 94 2e-18
UniRef50_Q643C6 Cluster: Mannopeptimycin peptide synthetase MppB... 94 2e-18
UniRef50_Q0S5D8 Cluster: Non-ribosomal peptide synthetase; n=2; ... 94 2e-18
UniRef50_Q0P7K0 Cluster: Putative non-ribosomal peptide synthase... 94 2e-18
UniRef50_O68487 Cluster: Actinomycin synthetase II; n=1; Strepto... 94 2e-18
UniRef50_A7IJ32 Cluster: Amino acid adenylation domain; n=1; Xan... 94 2e-18
UniRef50_Q98JF4 Cluster: Peptide synthetase; n=1; Mesorhizobium ... 93 3e-18
UniRef50_Q93H04 Cluster: Non-ribosomal peptide synthetase; n=1; ... 93 3e-18
UniRef50_Q8YWG6 Cluster: Peptide synthetase; n=3; Nostocaceae|Re... 93 3e-18
UniRef50_Q2JYI9 Cluster: Vicibactin biosynthesis non-ribosomal p... 93 3e-18
UniRef50_Q9F5J4 Cluster: SimH; n=5; Streptomyces|Rep: SimH - Str... 93 3e-18
UniRef50_Q7CT27 Cluster: AGR_L_2309p; n=2; Agrobacterium tumefac... 93 3e-18
UniRef50_Q45R83 Cluster: Peptide synthetase; n=3; Actinobacteria... 93 3e-18
UniRef50_Q2L5R6 Cluster: Putative peptide synthetase; n=1; Clost... 93 3e-18
UniRef50_Q1D591 Cluster: Nonribosomal peptide synthetase; n=1; M... 93 3e-18
UniRef50_Q183T6 Cluster: D-alanine--poly(Phosphoribitol) ligase ... 93 3e-18
UniRef50_Q0S5F4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 93 3e-18
UniRef50_A7BKG9 Cluster: Peptide synthetase; n=2; Beggiatoa|Rep:... 93 3e-18
UniRef50_A6UN01 Cluster: Amino acid adenylation domain; n=1; Sin... 93 3e-18
UniRef50_A6UN00 Cluster: Amino acid adenylation domain; n=1; Sin... 93 3e-18
UniRef50_Q8CUZ9 Cluster: Monomodular nonribosomal peptide synthe... 93 4e-18
UniRef50_Q4KAY8 Cluster: Pyochelin synthetase F; n=1; Pseudomona... 93 4e-18
UniRef50_Q2Y7Z2 Cluster: Amino acid adenylation; n=1; Nitrosospi... 93 4e-18
UniRef50_Q8GAQ3 Cluster: BarG; n=1; Lyngbya majuscula|Rep: BarG ... 93 4e-18
UniRef50_Q0S6F3 Cluster: Non-ribosomal peptide synthetase; n=2; ... 93 4e-18
UniRef50_A6GK66 Cluster: Non-ribosomal peptide synthetase; n=1; ... 93 4e-18
UniRef50_A4C385 Cluster: Amino acid adenylation; n=6; Pseudoalte... 93 4e-18
UniRef50_A4BRH6 Cluster: Amino acid adenylation; n=1; Nitrococcu... 93 4e-18
UniRef50_A1TTI9 Cluster: Amino acid adenylation domain; n=1; Aci... 93 4e-18
UniRef50_A1G2S7 Cluster: Amino acid adenylation domain; n=1; Sal... 93 4e-18
UniRef50_Q70LM7 Cluster: Linear gramicidin synthetase subunit A ... 93 4e-18
UniRef50_Q8U9P4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 93 5e-18
UniRef50_Q9R686 Cluster: Gramicidin S synthetase 2, GRSB; n=1; B... 93 5e-18
UniRef50_Q0LP45 Cluster: Amino acid adenylation; n=1; Herpetosip... 93 5e-18
UniRef50_Q0LKI6 Cluster: Amino acid adenylation; n=1; Herpetosip... 93 5e-18
UniRef50_A6VVR6 Cluster: Amino acid adenylation domain; n=1; Mar... 93 5e-18
UniRef50_A1FGJ4 Cluster: Amino acid adenylation; n=1; Pseudomona... 93 5e-18
UniRef50_A0QHN3 Cluster: Syringomycin synthetase; n=3; Mycobacte... 93 5e-18
UniRef50_Q8U9Q1 Cluster: Peptide synthetase; n=1; Agrobacterium ... 92 7e-18
UniRef50_Q39GN5 Cluster: Non-ribosomal peptide synthase; n=16; B... 92 7e-18
UniRef50_Q2T5X7 Cluster: Peptide synthetase, putative; n=9; Burk... 92 7e-18
UniRef50_Q9FB33 Cluster: Peptide synthetase NRPS11-10; n=1; Stre... 92 7e-18
UniRef50_Q54298 Cluster: Pipecolate incorporating enzyme; n=4; c... 92 7e-18
UniRef50_Q21E99 Cluster: Amino acid adenylation; n=2; Bacteria|R... 92 7e-18
UniRef50_Q0SK68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 92 7e-18
UniRef50_A5A9U3 Cluster: Mps2 protein; n=2; Mycobacterium|Rep: M... 92 7e-18
UniRef50_A0UWE6 Cluster: Amino acid adenylation domain; n=1; Clo... 92 7e-18
UniRef50_A0PTU7 Cluster: Non-ribosomal peptide synthetase MbtF; ... 92 7e-18
UniRef50_A0ACQ7 Cluster: Putative peptide synthetase; n=1; Strep... 92 7e-18
UniRef50_P29698 Cluster: Enterobactin synthetase component F; n=... 92 7e-18
UniRef50_Q63CQ7 Cluster: Multifunctional nonribosomal peptide sy... 92 9e-18
UniRef50_Q4JTA1 Cluster: Non-ribosomal peptide synthetase; n=1; ... 92 9e-18
UniRef50_Q9FB24 Cluster: Peptide synthetase NRPS6; n=8; cellular... 92 9e-18
UniRef50_Q1D592 Cluster: Non-ribosomal peptide synthase/polyketi... 92 9e-18
UniRef50_Q1D4E9 Cluster: Non-ribosomal peptide synthase/polyketi... 92 9e-18
UniRef50_Q197G2 Cluster: Nonribosomal peptide synthetase; n=2; S... 92 9e-18
UniRef50_Q0LP42 Cluster: Amino acid adenylation; n=1; Herpetosip... 92 9e-18
UniRef50_A6VYF6 Cluster: Amino acid adenylation domain; n=1; Mar... 92 9e-18
UniRef50_A5W126 Cluster: Amino acid adenylation domain; n=2; Pse... 92 9e-18
UniRef50_A0U0U6 Cluster: Amino acid adenylation domain; n=5; Bur... 92 9e-18
UniRef50_P39845 Cluster: Peptide synthetase 1; n=8; Bacillus|Rep... 92 9e-18
UniRef50_Q6VT93 Cluster: Mixed type I polyketide synthase-peptid... 91 1e-17
UniRef50_Q1D3S3 Cluster: Non-ribosomal peptide synthase; n=3; Ba... 91 1e-17
UniRef50_A5FI45 Cluster: Amino acid adenylation domain; n=1; Fla... 91 1e-17
UniRef50_A4F9A4 Cluster: CDA peptide synthetase I; n=1; Saccharo... 91 1e-17
UniRef50_A3INW7 Cluster: Amino acid adenylation; n=1; Cyanothece... 91 1e-17
UniRef50_Q8GGR4 Cluster: Nonribosomal peptide synthetase; n=1; S... 91 2e-17
UniRef50_Q847C7 Cluster: NdaA; n=5; cellular organisms|Rep: NdaA... 91 2e-17
UniRef50_Q9FDB0 Cluster: Six-domain nonribosomal peptide synthet... 91 2e-17
UniRef50_Q2AZ45 Cluster: Amino acid adenylation; n=2; Bacillus c... 91 2e-17
UniRef50_Q0W980 Cluster: Non-ribosomal peptide synthetase; n=2; ... 91 2e-17
UniRef50_A1TG57 Cluster: Non-ribosomal peptide synthetase; n=3; ... 91 2e-17
UniRef50_A0ADQ3 Cluster: Putative non-ribosomal peptide syntheta... 91 2e-17
UniRef50_Q2SHZ1 Cluster: Non-ribosomal peptide synthetase module... 90 3e-17
UniRef50_Q5ZPA8 Cluster: TubD protein; n=4; cellular organisms|R... 90 3e-17
UniRef50_Q12IB9 Cluster: Amino acid adenylation; n=3; cellular o... 90 3e-17
UniRef50_Q0X0B9 Cluster: Putative non-ribosomal peptide syntheta... 90 3e-17
UniRef50_A4X8R2 Cluster: Amino acid adenylation domain; n=1; Sal... 90 3e-17
UniRef50_A4C386 Cluster: Amino acid adenylation; n=1; Pseudoalte... 90 3e-17
UniRef50_A1TTI8 Cluster: Amino acid adenylation domain; n=1; Aci... 90 3e-17
UniRef50_Q9I157 Cluster: PvdL; n=23; root|Rep: PvdL - Pseudomona... 90 4e-17
UniRef50_Q4ZV22 Cluster: Amino acid adenylation; n=3; Pseudomona... 90 4e-17
UniRef50_Q12Q14 Cluster: Amino acid adenylation; n=1; Shewanella... 90 4e-17
UniRef50_Q12IB7 Cluster: Amino acid adenylation; n=1; Shewanella... 90 4e-17
UniRef50_Q0TGF7 Cluster: Probable peptide synthetase protein; n=... 90 4e-17
UniRef50_Q0LN53 Cluster: Amino acid adenylation; n=1; Herpetosip... 90 4e-17
UniRef50_A4XD41 Cluster: Amino acid adenylation domain precursor... 90 4e-17
UniRef50_P26046 Cluster: N-(5-amino-5-carboxypentanoyl)-L-cystei... 90 4e-17
UniRef50_Q81DB7 Cluster: Peptide synthetase; n=4; Bacillus cereu... 89 5e-17
UniRef50_Q4ZVI2 Cluster: Amino acid adenylation; n=4; Pseudomona... 89 5e-17
UniRef50_Q2T4N2 Cluster: Thiotemplate mechanism natural product ... 89 5e-17
UniRef50_Q8G983 Cluster: Peptide synthetase; n=118; cellular org... 89 5e-17
UniRef50_Q0RI62 Cluster: Putative siderophore related no-ribosom... 89 5e-17
UniRef50_A3VRW5 Cluster: Probable peptide synthetase protein; n=... 89 5e-17
UniRef50_UPI00005F40EE Cluster: hypothetical protein VchoR_02002... 89 6e-17
UniRef50_Q8PKR7 Cluster: ATP-dependent serine activating enzyme;... 89 6e-17
UniRef50_Q6N4J7 Cluster: Peptide synthetase; n=1; Rhodopseudomon... 89 6e-17
UniRef50_Q52379 Cluster: Amino acid-adenylating enzyme; n=3; Pse... 89 6e-17
UniRef50_Q45R84 Cluster: Peptide synthetase; n=3; Bacteria|Rep: ... 89 6e-17
UniRef50_Q0LIS7 Cluster: Amino acid adenylation; n=1; Herpetosip... 89 6e-17
UniRef50_A6YEH2 Cluster: CmnA; n=1; Saccharothrix mutabilis subs... 89 6e-17
UniRef50_A1FGJ1 Cluster: Amino acid adenylation; n=1; Pseudomona... 89 6e-17
UniRef50_P27743 Cluster: N-(5-amino-5-carboxypentanoyl)-L-cystei... 89 6e-17
UniRef50_Q982I6 Cluster: Peptide synthetase; n=1; Mesorhizobium ... 89 8e-17
UniRef50_Q4ZMD3 Cluster: Amino acid adenylation; n=5; Proteobact... 89 8e-17
UniRef50_Q5IW60 Cluster: Phosphinothricin tripeptide synthetase ... 89 8e-17
UniRef50_Q4C639 Cluster: Amino acid adenylation; n=1; Crocosphae... 89 8e-17
UniRef50_Q2MFA3 Cluster: Putative nonribosomal peptide synthetas... 89 8e-17
UniRef50_Q02HM0 Cluster: Putative non-ribosomal peptide syntheta... 89 8e-17
UniRef50_A3IRQ7 Cluster: Amino acid adenylation; n=2; Chroococca... 89 8e-17
UniRef50_A1TW55 Cluster: Amino acid adenylation domain; n=1; Aci... 89 8e-17
UniRef50_A2QIQ8 Cluster: Remark: the terminal NRPS; n=2; Aspergi... 89 8e-17
UniRef50_A1CLY8 Cluster: Hybrid NRPS/PKS enzyme, putative; n=1; ... 89 8e-17
UniRef50_Q4ZV21 Cluster: Non-ribosomal peptide synthase:Amino ac... 88 1e-16
UniRef50_Q1D437 Cluster: Non-ribosomal peptide synthetase/polyke... 88 1e-16
UniRef50_A1G7D3 Cluster: Amino acid adenylation domain; n=3; Act... 88 1e-16
UniRef50_Q6Q883 Cluster: SirP; n=2; Ascomycota|Rep: SirP - Lepto... 88 1e-16
>UniRef50_Q402E3 Cluster: Ebony; n=4; Neoptera|Rep: Ebony - Papilio
xuthus
Length = 861
Score = 254 bits (622), Expect = 1e-66
Identities = 119/181 (65%), Positives = 143/181 (79%)
Frame = +3
Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHN 182
Q+ I T+PIG P+ N +YLLDE M RE EPGEV VAG NLA GYV G+ P +F +N
Sbjct: 352 QLDIHPTIPIGKPVDNCAIYLLDEEMNPAREAEPGEVWVAGSNLAAGYVGGQAPEKFCYN 411
Query: 183 PHNTHPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
PH +HP+F KLYRTGDFG+L KG+ILYAGR DSQVKIRGHRVDL EV+ AVS + ++
Sbjct: 412 PHASHPDFGKLYRTGDFGVLHKGMILYAGRTDSQVKIRGHRVDLLEVETAVSAVEGIEKA 471
Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIETVPVLVNGK 542
VVLCYG+E NPE+LAFVTI+P+AR+SA +IEA L +SLT YM+PQVI IE VP+LVNGK
Sbjct: 472 VVLCYGLERGNPEVLAFVTISPDARLSAHHIEAALKNSLTHYMLPQVIVIEAVPLLVNGK 531
Query: 543 V 545
V
Sbjct: 532 V 532
>UniRef50_Q9GSP4 Cluster: Mutant e4 ebony; n=2; Drosophila|Rep:
Mutant e4 ebony - Drosophila melanogaster (Fruit fly)
Length = 735
Score = 200 bits (489), Expect = 1e-50
Identities = 96/182 (52%), Positives = 123/182 (67%), Gaps = 1/182 (0%)
Frame = +3
Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHN 182
Q+ ++ VPIG+P+SN VYLLD + R V+ GE GE+ +G NLA GYV G+DP RF+ N
Sbjct: 216 QLSLYDNVPIGIPLSNTVVYLLDADYRPVKNGEIGEIFASGLNLAAGYVNGRDPERFLEN 275
Query: 183 PHNTHPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
P +A+LYRTGD+G L G I+Y GR DSQVKIRGHRVDL EV+ V+ +P VD
Sbjct: 276 PLAVEKKYARLYRTGDYGSLKNGSIMYEGRTDSQVKIRGHRVDLSEVEKNVAELPLVDKA 335
Query: 363 VVLCYGVESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQVIEIETVPVLVNG 539
+VLCY + ILAFV + +A M + +EA L L DYM PQV+ +E VP+LVNG
Sbjct: 336 IVLCYHAGQVDQAILAFVKLRDDAPMVTETQMEARLKDKLADYMTPQVVILEHVPLLVNG 395
Query: 540 KV 545
KV
Sbjct: 396 KV 397
>UniRef50_O76858 Cluster: Ebony protein; n=18; Diptera|Rep: Ebony
protein - Drosophila melanogaster (Fruit fly)
Length = 879
Score = 200 bits (489), Expect = 1e-50
Identities = 96/182 (52%), Positives = 123/182 (67%), Gaps = 1/182 (0%)
Frame = +3
Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHN 182
Q+ ++ VPIG+P+SN VYLLD + R V+ GE GE+ +G NLA GYV G+DP RF+ N
Sbjct: 360 QLSLYDNVPIGIPLSNTVVYLLDADYRPVKNGEIGEIFASGLNLAAGYVNGRDPERFLEN 419
Query: 183 PHNTHPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
P +A+LYRTGD+G L G I+Y GR DSQVKIRGHRVDL EV+ V+ +P VD
Sbjct: 420 PLAVEKKYARLYRTGDYGSLKNGSIMYEGRTDSQVKIRGHRVDLSEVEKNVAELPLVDKA 479
Query: 363 VVLCYGVESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQVIEIETVPVLVNG 539
+VLCY + ILAFV + +A M + +EA L L DYM PQV+ +E VP+LVNG
Sbjct: 480 IVLCYHAGQVDQAILAFVKLRDDAPMVTETQMEARLKDKLADYMTPQVVILEHVPLLVNG 539
Query: 540 KV 545
KV
Sbjct: 540 KV 541
>UniRef50_UPI0000DB6BFA Cluster: PREDICTED: similar to ebony
CG3331-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
to ebony CG3331-PA - Apis mellifera
Length = 860
Score = 168 bits (409), Expect = 6e-41
Identities = 76/173 (43%), Positives = 113/173 (65%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
VPIG P+ N +Y+++++MR + +GE GE+ VAG NLA GY+ + +F NP+
Sbjct: 354 VPIGKPLDNCVIYIVNKDMRLIPQGEVGELIVAGRNLATGYIHNNESRKFQDNPYTIDLE 413
Query: 204 FAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGV 383
++++Y TGD+ + KGVI+Y GR DSQ+K+RGHRVDL EV+ +S I +D +VLCY
Sbjct: 414 YSRIYCTGDYAKISKGVIMYEGRVDSQIKVRGHRVDLTEVEKVISRISEIDGVIVLCYKP 473
Query: 384 ESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIETVPVLVNGK 542
+ ++AFVTI ++ IE L S L YM+P+VI +E +P+L NGK
Sbjct: 474 GELSQSLVAFVTIAKDSSTCVSKIETFLQSMLPIYMLPRVIIVENIPLLTNGK 526
>UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2;
Cyanobacteria|Rep: Amino acid adenylation - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 2791
Score = 124 bits (300), Expect = 1e-27
Identities = 62/179 (34%), Positives = 109/179 (60%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194
++PIG PISN +Y+L+ +++ V G PGE+ + GF +++GY+ + +FI +P +
Sbjct: 2569 SIPIGRPISNTQIYILNSHLQPVPIGTPGEIYIGGFGVSKGYLNRPELTIEKFIPDPFSK 2628
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
PN A+LY+TGD L G I + GR D Q+K+RG+R++L E++ + P V +V+
Sbjct: 2629 QPN-ARLYKTGDQARYLSNGNIEFIGRIDHQIKLRGYRIELGEIEAVLQQHPQVKQAIVI 2687
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545
+S N +++A++ + + + L + L +YMIP VI +I+T+P+ NGK+
Sbjct: 2688 ARNSDSENQQLVAYIVPSQTQDSLTNELRSFLQTKLPNYMIPSVILQIDTLPLTPNGKI 2746
Score = 87.4 bits (207), Expect = 2e-16
Identities = 53/156 (33%), Positives = 84/156 (53%), Gaps = 4/156 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG I+N +Y+LD++++ V G PGE+ + G +ARGY+ +FI NP + +
Sbjct: 1463 VPIGRAIANTQIYILDKHLQPVPIGVPGELHIGGVGVARGYLNQPQLTAEKFIVNPFSNN 1522
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
N +LY+TGD G I Y GR D QVK+RG R++L E++ ++ P V VV+
Sbjct: 1523 SN-NRLYKTGDLARYHTDGSIEYLGRLDDQVKLRGFRIELTEIESVLTQHPDVRKAVVVM 1581
Query: 375 YGVESSNPEILAFVTINPEARMSAKN-IEAELTSSL 479
+ +++ N +N ++ ELT L
Sbjct: 1582 RETSAVKRQVVLNPPENNSEITDLRNFLKGELTEEL 1617
Score = 47.2 bits (107), Expect = 2e-04
Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNT 194
+ V G P+++ + ++D + + + + GE+ VAG ++A+GY + +
Sbjct: 372 ILVGCGQPLADLKIVIVDPQTLSACSDRQVGEIWVAGASVAQGYWHQPEQTESTFKAYTK 431
Query: 195 HPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV 335
RTGD G L G + GR + IRG Q++++ V
Sbjct: 432 DTKEGPFLRTGDLGFLQDGELFITGRLKDLIIIRGRNYYPQDIENTV 478
Score = 33.9 bits (74), Expect = 2.5
Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Frame = +3
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
VES+ +++A+ + + + L L DYMIP I ++ +PV NGK+
Sbjct: 1619 VESTTKQLIAYCVCRHQPAPNITKLRRFLGEKLPDYMIPATFIMLDALPVTANGKL 1674
>UniRef50_Q08787 Cluster: Surfactin synthetase subunit 3; n=9;
Bacillus|Rep: Surfactin synthetase subunit 3 - Bacillus
subtilis
Length = 1274
Score = 124 bits (299), Expect = 1e-27
Identities = 71/179 (39%), Positives = 106/179 (59%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++PIG PISN VY+L+E + G GE+C++G +++GYV D +FI NP
Sbjct: 776 SLPIGKPISNASVYILNEQSQLQPFGAVGELCISGMGVSKGYVNRADLTKEKFIENPFKP 835
Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
LYRTGD L G I YAGR D QVKIRGHR++L+E++ + P V + VV+
Sbjct: 836 GET---LYRTGDLARWLPDGTIEYAGRIDDQVKIRGHRIELEEIEKQLQEYPGVKDAVVV 892
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
ES + I A++ +N ++SA++++A L L YM+PQ ++ +P+ NGKV
Sbjct: 893 ADRHESGDASINAYL-VN-RTQLSAEDVKAHLKKQLPAYMVPQTFTFLDELPLTTNGKV 949
>UniRef50_Q0LPK1 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1714
Score = 121 bits (292), Expect = 9e-27
Identities = 65/179 (36%), Positives = 104/179 (58%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+PIG PI N ++LD M+ V G GE+ + G LARGY R D RF+ +P +T
Sbjct: 333 TIPIGYPIDNLTTWVLDAQMQPVAVGRSGELYIGGMGLARGYQRQPDRSAERFVPDPFST 392
Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +LY+TGD +L G +L+ R D Q+K+RG+R++L E+ + P + VV+
Sbjct: 393 QPG-TRLYKTGDRVRLLANGALLFLDRIDQQIKLRGYRIELGEIQAGLERHPQIRQSVVV 451
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ +++A+V PEAR+ + + A L + L YM+P + +E +P+L NGK+
Sbjct: 452 GQLDQTKTLQLVAYVVPMPEARIPIEQLRALLKAQLPRYMLPSAFVILERLPLLANGKL 510
Score = 93.5 bits (222), Expect = 3e-18
Identities = 57/177 (32%), Positives = 92/177 (51%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG I VY+LD ++ + G G++ +AG LA GY+ D F+ NP + P
Sbjct: 1402 PIGRAIQQMAVYVLDRELQPMPTGVIGDIYIAGIGLALGYIAKPDLTAEVFLPNPLSAEP 1461
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YR+GD G L G +++ GR+D QVKIRG R++L E+ V V VV Y
Sbjct: 1462 GM-RMYRSGDRGRYLADGSLMFVGRSDRQVKIRGMRIELNEIRTCVLQHAQVHEAVVNIY 1520
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ NP+I+A+V ++ ++ + L M PQ + ++ +P+ N K+
Sbjct: 1521 NDQPDNPQIVAYVVPTKGQLLTEASLRTYIGQKLPLAMQPQAFVLLDRLPLTANDKL 1577
>UniRef50_A1KQR7 Cluster: RhiB protein; n=1; Burkholderia
rhizoxina|Rep: RhiB protein - Burkholderia rhizoxina
Length = 6722
Score = 121 bits (292), Expect = 9e-27
Identities = 67/177 (37%), Positives = 103/177 (58%), Gaps = 4/177 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI N +Y+LD + V GE GE+C+ G LARGY+ + +FI +P +
Sbjct: 256 VPIGRPIDNIQIYILDSEAKPVPIGETGELCIGGLGLARGYLNRPELTAEKFIRDPFSGE 315
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A+LYRTGD L G I GR DSQVK+RG R++L E++ A+ + P +D+ VL
Sbjct: 316 AG-ARLYRTGDKARFLSNGEIELLGRFDSQVKLRGFRIELGEIESALKSHPAIDDAAVLV 374
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGK 542
S++P+++AFV + K + + + L +YM+P ++ I+ +PV +GK
Sbjct: 375 KDPGSADPKLVAFVVAQ---GLDKKAVRDFIKARLPEYMVPNLVSFIDQIPVTAHGK 428
>UniRef50_Q8VQF9 Cluster: Peptide synthetase XpsA; n=1; Xenorhabdus
bovienii|Rep: Peptide synthetase XpsA - Xenorhabdus
bovienii
Length = 1089
Score = 120 bits (290), Expect = 2e-26
Identities = 67/183 (36%), Positives = 109/183 (59%), Gaps = 4/183 (2%)
Frame = +3
Query: 9 HIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN 182
HI L VPIG PI N +Y+LD++ + V G GE+ +AG +ARGY+ + RFI +
Sbjct: 797 HIGL-VPIGHPIDNTQIYILDKHDQPVPIGVIGEIYIAGAGVARGYLNKPELTAERFIRD 855
Query: 183 PHNTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359
P + HP+ ++Y+TGD G L G I Y GR D QVKIRG+R++L E++ ++ V N
Sbjct: 856 PFSQHPDM-RMYKTGDIGRWLADGSIDYLGRNDFQVKIRGNRIELGEIEARLAQSDGVQN 914
Query: 360 CVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536
+V+ ++ + ++A++ P +S + ++ SL DYMIP + ++ P+ +N
Sbjct: 915 VIVIAREYDAGDTRLVAYLIPKPGVTLSIPALREQVGGSLPDYMIPSAFVMLDAFPLTLN 974
Query: 537 GKV 545
GK+
Sbjct: 975 GKL 977
>UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular
organisms|Rep: CDA peptide synthetase I - Streptomyces
coelicolor
Length = 7463
Score = 119 bits (287), Expect = 4e-26
Identities = 63/178 (35%), Positives = 101/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P +N VY+LD +R V G GE+ +AG LARGY+ RF NPH++
Sbjct: 4565 VPIGRPFANTQVYVLDSALRPVAPGVTGELYLAGEQLARGYLGRPALTAERFTANPHSST 4624
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YRTGD + G + Y GRAD Q+K+RGHR++ E++ ++ + V
Sbjct: 4625 PG-ARMYRTGDLAHWNHHGHLTYDGRADHQIKLRGHRIEPGEIEATLTAQTGITQATVQL 4683
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + ++A++ +N K + LTS+L DYM+P ++ ++ +P+ NGK+
Sbjct: 4684 REDQPGDQRLVAYLVVNDSTEYDEKTVRDALTSALPDYMVPSALVTLDALPLTPNGKL 4741
Score = 111 bits (266), Expect = 1e-23
Identities = 65/177 (36%), Positives = 100/177 (56%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHP 200
PIG P++N+ VY+LD +R V G PGE+ AG +LARGY R RF+ NP P
Sbjct: 3070 PIGSPVANSAVYVLDAALRPVPPGVPGELYAAGAHLARGYHDRRALTAERFVANPFG-EP 3128
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++LYRTGD G + Y GRAD+QVKIRG R++ E++ ++ P + V+
Sbjct: 3129 G-SRLYRTGDLVRWRPDGQLEYLGRADTQVKIRGLRIEPTEIEAVITERPHLARAAVIVR 3187
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V P A + + A L +L D+MIP + ++ +P+ +NGK+
Sbjct: 3188 EDRPGDRRLVAYVVPEPGATVDTAELRAALRETLPDHMIPTAFVVLDALPLTLNGKL 3244
Score = 110 bits (264), Expect = 2e-23
Identities = 61/178 (34%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P +N VY+LD +R V G GE+ +AG LARGY+ RF NPH++
Sbjct: 5605 VPIGRPFANTQVYVLDSALRPVAPGVTGELYLAGEQLARGYLGRPALTAERFTANPHSST 5664
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YRTGD + G + Y GRAD Q+K+RGHR++ E++ ++ + V
Sbjct: 5665 PG-ARMYRTGDLAHWNHDGHLTYDGRADHQIKLRGHRIEPGEIETTLTAQTGITQTTVQL 5723
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A++ +N + L S+L DYM P + ++ +P+ NGK+
Sbjct: 5724 REDTPGDQRLVAYLVVNDSTEYDEPTLRDALASALPDYMRPSAYVTLDALPLTPNGKL 5781
Score = 91.1 bits (216), Expect = 2e-17
Identities = 59/178 (33%), Positives = 93/178 (52%), Gaps = 6/178 (3%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT--H 197
IGV I + VY+LD+ +R G GE+ VAG LARGY+ RF +P+
Sbjct: 2004 IGVNIPDLRVYVLDDRLRPTAPGVTGEMYVAGAGLARGYLGRPALTADRFPADPYAALFG 2063
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G + Y GRAD QVKIRG R++ E++ ++ P VD+ V+
Sbjct: 2064 ERGTRMYRTGDLARRRTDGGLDYLGRADQQVKIRGFRIEPGEIEAVLAAHPAVDDVAVVA 2123
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+P ++A+V A +A+ + L D+M+P + ++ +P+ NGK+
Sbjct: 2124 REDVQGDPRLVAYVVTGSGA--TARALHDHAAGHLPDHMLPSAFVTLDVLPLTPNGKL 2179
Score = 90.2 bits (214), Expect = 3e-17
Identities = 56/181 (30%), Positives = 95/181 (52%), Gaps = 6/181 (3%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++P+G N Y+LD ++ V G PGE+ ++G LARGY+ D RF+ +P+
Sbjct: 6685 SLPVGRATGNTRAYVLDRYLQPVPAGVPGELFISGSGLARGYLDRPDLTCERFVADPYG- 6743
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ ++YRTGD + G + Y RAD QVKIRG RV+L E++ ++T P + V+
Sbjct: 6744 -GSGERMYRTGDLVRYNAAGELEYLARADDQVKIRGFRVELGEIEAVLATRPELAQAAVV 6802
Query: 372 CYGVESSNPEILAFV--TINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542
+ ++ +V + + + A +L DYM+P + + T+P+ NGK
Sbjct: 6803 VREDRPGDRRLVGYVVAAAGRDGEVDPDALRAFSRQALPDYMVPSAFVVLGTLPLTANGK 6862
Query: 543 V 545
+
Sbjct: 6863 L 6863
Score = 85.4 bits (202), Expect = 8e-16
Identities = 50/133 (37%), Positives = 75/133 (56%), Gaps = 3/133 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
VPIG P+ N +Y+LD +R V G PGE+ +AG LARGY+ RF +PH
Sbjct: 792 VPIGRPVWNTRMYVLDAALRPVPAGVPGELYIAGVQLARGYLGRPALSAERFTADPHGA- 850
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +++YRTGD + G + Y GRAD QVK+RG R++L E++ A+ P + V+
Sbjct: 851 PG-SRMYRTGDLARWNHDGSLDYLGRADHQVKLRGFRIELGEIEAALVRQPEIAQAAVVL 909
Query: 375 YGVESSNPEILAF 413
+ ++A+
Sbjct: 910 REDRPGDQRLVAY 922
>UniRef50_Q8VQF8 Cluster: Peptide synthetase XpsB; n=1; Xenorhabdus
bovienii|Rep: Peptide synthetase XpsB - Xenorhabdus
bovienii
Length = 3316
Score = 119 bits (287), Expect = 4e-26
Identities = 61/179 (34%), Positives = 108/179 (60%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+ IG PI+N +Y+LD + V G GE+ + G +ARGY+ + RF+ +P++
Sbjct: 3011 TLSIGRPIANTRIYILDTRGQPVPTGVTGEIYIGGAGVARGYLNRPELTTERFVSDPYSE 3070
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
PN A++YRTGD G G I+Y GR D QVK+RG R++L E++ ++ V + VV+
Sbjct: 3071 QPN-ARMYRTGDLGCWQPDGTIVYLGRNDFQVKLRGFRIELGEIETQLAACLGVKDAVVV 3129
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ + ++A+V P+A + A ++ +L++ LT+YM+P + ++ P+ +GK+
Sbjct: 3130 AREEDAGDKRLVAYVIPQPDASLDAASLREQLSTHLTEYMLPSAFVILDAFPLTPSGKL 3188
Score = 117 bits (282), Expect = 2e-25
Identities = 63/178 (35%), Positives = 108/178 (60%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI+N +Y+LD+ + V G GE+ ++G +ARGY+ + RFI +P +
Sbjct: 832 IPIGRPIANTRIYILDQRGQPVPIGVNGEIHISGSGVARGYLNRSELTAERFIQDPFSDI 891
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++Y+TGD G L G I Y+GR D QVKIRG R++L E++ ++T V + VV+
Sbjct: 892 PG-ARMYKTGDLGRWLPDGTISYSGRNDFQVKIRGFRIELGEIEAQLATCAGVKDAVVIV 950
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ + ++A++ A ++A ++ +L+ +L DYM+P + +E P+ NGK+
Sbjct: 951 REDDNGDKRLVAYLIPQSGAILNAASLREQLSVNLADYMLPSAFVTLEAFPLNQNGKI 1008
Score = 107 bits (257), Expect = 2e-22
Identities = 57/179 (31%), Positives = 102/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++ IG P+ N +VY+LD + V G GE+ + G +ARGY+ + RF+ +P
Sbjct: 1905 SLSIGRPLINTHVYILDTQGQPVPIGVTGEIYIGGAGVARGYLNRPELTAERFVSDPFRE 1964
Query: 195 HPNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P+ A++YRTGD G G I+Y GR D QVKIRG R++L E++ ++ V + VV+
Sbjct: 1965 QPH-ARMYRTGDLGCWRPDGTIVYLGRNDFQVKIRGFRIELGEIESQLAACTGVSDAVVV 2023
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
S + ++A++ + + A ++ ++++ L +YM+P + ++ P+ NGK+
Sbjct: 2024 AREEGSGDKRLVAYLVPKSDVTLDAASLREQVSTHLAEYMLPSAFVILDAFPLNPNGKL 2082
>UniRef50_Q4C3C2 Cluster: Amino acid adenylation; n=1; Crocosphaera
watsonii WH 8501|Rep: Amino acid adenylation -
Crocosphaera watsonii
Length = 1539
Score = 119 bits (287), Expect = 4e-26
Identities = 64/179 (35%), Positives = 103/179 (57%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PI+N Y+LD N++ V G PGE+ + G LARGY+ + RFI NP
Sbjct: 777 SVPIGRPIANTQTYILDVNLQPVPVGVPGELYLGGVQLARGYLNRPELTAERFIENPFRE 836
Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ +++LY+TGD L G I Y GR D+QVKIRG R++L E++ ++ V VV+
Sbjct: 837 NFGYSRLYKTGDLVCYLPDGNIEYLGRLDNQVKIRGLRIELGEIEAQIAQYETVKEAVVI 896
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A++ E+ +++ + L L +YMIP + +E +P+ NGK+
Sbjct: 897 AREEIAGDKRLVAYLVPQEESTVNSSKLRKFLREKLPNYMIPSAFVTLEELPLTPNGKI 955
>UniRef50_Q0B1F6 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain -
Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 3018
Score = 119 bits (287), Expect = 4e-26
Identities = 63/178 (35%), Positives = 102/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPHNTH 197
VP+G PI N +Y++D M G PGE+CV+G + RGY+ + R F+ +P
Sbjct: 762 VPVGKPIRNVRIYVVDPQMNLCPIGVPGELCVSGVAVGRGYLNNEAGTREAFLEDPFRAE 821
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRT D G L G I+ GR D Q+KIRG+R++L E+D+A++ IP + L
Sbjct: 822 SG-VRMYRTRDIGCYLPDGSIVLHGRKDHQLKIRGYRIELGEIDNALAAIPEIRQAAALD 880
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
Y ++ + A+V A +S I A L+++L DYM+P + + ++ +P+ NGK+
Sbjct: 881 YRDDAGRAALCAYVAFRAGASLSDAEIAAALSATLPDYMVPGIYVVLDALPLSGNGKI 938
Score = 98.3 bits (234), Expect = 1e-19
Identities = 57/178 (32%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPHNTH 197
+PIG PI N VY++D +M G GE+C+ G + RGY+ + R F +P +
Sbjct: 2275 IPIGRPIENLRVYVVDADMNLCPVGVKGEICIGGAGVGRGYLFDEARTRAVFRDDPFSPE 2334
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LYRTGD G G + + GR D QVKIRG+R++L E++ A++ + + N VV+
Sbjct: 2335 PG-ARLYRTGDVGCFGSDGNLHFFGRRDFQVKIRGYRIELGEIETALTGLAGISNAVVVV 2393
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ + + + + K + L L +M+P + + +PV+ NGK+
Sbjct: 2394 RDTPDAEKTLCGYAS---GTGWTPKRLRDALRDKLPAHMVPDTLMLLSALPVMPNGKI 2448
>UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibiotic
biosynthesis; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to proteins involved in antibiotic
biosynthesis - Photorhabdus luminescens subsp. laumondii
Length = 3270
Score = 118 bits (285), Expect = 7e-26
Identities = 67/179 (37%), Positives = 105/179 (58%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+ IG PI N ++LLD+N + V G GE+CVAG +ARGY+ + RFI NP +
Sbjct: 1902 TLSIGHPIQNTAIFLLDKNQQLVPFGAVGEICVAGDGVARGYINKEQLTRERFIDNPFVS 1961
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ KLYRTGD G G I Y GR D QVKIRG R++L E++ + ++P + + VV+
Sbjct: 1962 --RYPKLYRTGDLGRYSLAGDIQYYGRDDHQVKIRGFRIELGEIETRLRSLPTIRDAVVI 2019
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E ++ + A++T++ + +++ I L+ L YM+P + +E +P+ N KV
Sbjct: 2020 AREDEPAHKYLAAYITLDGQQKVA--EIRHLLSQQLPSYMVPAAFVVLEEIPLTANRKV 2076
Score = 106 bits (254), Expect = 4e-22
Identities = 58/178 (32%), Positives = 100/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V IG+P++N +YLLDE ++ V G GE+ + G LA GY + +D R I+ +
Sbjct: 845 VTIGLPLNNTTIYLLDEQLKPVPFGAVGELYIGGDGLAEGYFKREDLTTERLINLTFSDG 904
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
AK+Y+TGD +G ++Y GR D QVK+RGHR++L E++ ++ P + VV+
Sbjct: 905 LT-AKVYKTGDLARYTTEGSLVYLGRNDYQVKLRGHRIELGEIEQVINLFPQITRSVVVA 963
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + + +V + + A + L L YM+P+ +I++ET+P+ +N K+
Sbjct: 964 LNDQQTQQYLAGYVVAEQQIDIDA--LRQHLEQKLPAYMLPRAIIQLETLPLTLNNKI 1019
Score = 82.6 bits (195), Expect = 5e-15
Identities = 58/176 (32%), Positives = 90/176 (51%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFA 209
IG + N Y+LDE ++ V G GE+ +AG L+RGY + P +
Sbjct: 2985 IGRSLPNVAGYILDEYLQPVPMGAIGELYLAGDCLSRGYY--QQPQLTAERYLDCDWVLG 3042
Query: 210 K-LYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGV 383
K +YRTGD G I Y GR D VKIRG R++L +++ +S + VV+
Sbjct: 3043 KRVYRTGDLASFHQNGEINYFGRNDHLVKIRGFRIELGDIEAQLSKFDGITGTVVIAIDT 3102
Query: 384 ESSNPEILA-FVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E+ + +++A F+ NP + I+ L++SL DYM+P + + P+ NGKV
Sbjct: 3103 EAGDKQLIAYFIAANP---LDLSEIKTYLSASLPDYMLPSAYVRMAAFPLNTNGKV 3155
>UniRef50_Q2N3S9 Cluster: Hybrid nonribosomal peptide
synthetase/polyketide synthase; n=2; Proteobacteria|Rep:
Hybrid nonribosomal peptide synthetase/polyketide
synthase - Polyangium cellulosum (Sorangium cellulosum)
Length = 4641
Score = 118 bits (285), Expect = 7e-26
Identities = 66/178 (37%), Positives = 103/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LDE R VR + GE+ +AG LARGY+ + RF+ +P +
Sbjct: 1318 VPIGRPIANIRLYILDEQQRPVRPDQTGELYIAGVGLARGYLNRPELTAERFVRDPFDPS 1377
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++Y+TGD L G I + GR D Q+K+RG R++L E++ A+ V V
Sbjct: 1378 PG-ARMYKTGDRAAWLPDGNIDFLGRMDGQIKLRGLRIELGEIEAALLGHEAVREAAVAV 1436
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+S +P ++A+V + A S + + L SSL YM+P Q +++ +PV +GK+
Sbjct: 1437 RDADSGDPRLVAYVVLRDGASFSPQVMRRFLESSLPRYMVPNQFVQVAGIPVTAHGKM 1494
>UniRef50_Q84BC8 Cluster: NcpA; n=5; Cyanobacteria|Rep: NcpA - Nostoc
sp. ATCC 53789
Length = 3735
Score = 118 bits (284), Expect = 9e-26
Identities = 66/184 (35%), Positives = 103/184 (55%), Gaps = 10/184 (5%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP---- 185
+ IG PISN +Y+LD+N++ V G PGE+ + G LARGY++ + +FI NP
Sbjct: 1898 ISIGRPISNTQIYILDQNLQPVPIGVPGELHIGGAGLARGYLKRPELTQEKFIPNPFEEA 1957
Query: 186 --HNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVD 356
++LY+TGD L G I Y GR D+QVKIRG R++L E++ A+S P V
Sbjct: 1958 GGRGQEAGGSRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHPHVQ 2017
Query: 357 NCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLV 533
V+ + ++A++ P+ ++ + + L L DYM+P I I E++P+
Sbjct: 2018 ASCVIAREDTPGDKRLVAYIVPQPQVTLTISELRSNLKEKLPDYMVPSAIVILESLPLTP 2077
Query: 534 NGKV 545
NGK+
Sbjct: 2078 NGKI 2081
Score = 111 bits (266), Expect = 1e-23
Identities = 64/186 (34%), Positives = 101/186 (54%), Gaps = 12/186 (6%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI N +Y+LD+N++ V G PGE+ + G LA+GY+ + +FI NP
Sbjct: 2979 IPIGRPIDNTQIYILDQNLQPVPVGVPGELHIGGAGLAKGYLNLPELTQEKFIPNPFQGS 3038
Query: 198 PNFA--------KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPC 350
+LY+TGD L G I Y GR D+QVKIRG R++L E++ A+S
Sbjct: 3039 RGAGEQGSRGRERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHSD 3098
Query: 351 VDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPV 527
V VV+ N ++A+V P+ + + + L L +YM+P ++ +E++P+
Sbjct: 3099 VQTSVVIVREDIPGNKRLVAYVVPQPQITPTVSQLRSFLKEKLPEYMVPSAIVTLESLPL 3158
Query: 528 LVNGKV 545
NGK+
Sbjct: 3159 TPNGKI 3164
Score = 108 bits (259), Expect = 9e-23
Identities = 63/186 (33%), Positives = 100/186 (53%), Gaps = 12/186 (6%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+ IG PI+N +Y+LD ++ V G PGE+ + G +ARGY+ + +FI NP +
Sbjct: 835 ITIGRPIANAEIYILDSQLQPVPIGVPGELHIGGAGVARGYLNRNELTQQKFIPNPFSRS 894
Query: 198 PNFA--------KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPC 350
+LY+TGD L G I Y GR D+QVKIRG R++L E++ +S P
Sbjct: 895 RGAGEQGSRGRERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEATLSQHPH 954
Query: 351 VDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPV 527
V V+ + ++A++ + PE + K + + L L +YM+P I I E++P+
Sbjct: 955 VQASCVIAREDIPGDKRLIAYIVLQPEQTATVKELRSFLKEKLPEYMVPSAIAILESLPL 1014
Query: 528 LVNGKV 545
NGK+
Sbjct: 1015 TPNGKI 1020
>UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3;
cellular organisms|Rep: Non-ribosomal peptide synthetase
- Erwinia carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 7048
Score = 117 bits (282), Expect = 2e-25
Identities = 63/180 (35%), Positives = 101/180 (56%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
LTVPIG PI+N+ +Y+LD R GE+ + G +ARGY+ D RFI +P +
Sbjct: 5135 LTVPIGHPIANSQIYILDPQGRPTLLNVAGEIYIGGAGVARGYLNRPDLTAERFIPDPFS 5194
Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
+ P A++Y+TGD L G I Y GR D QVK+RG R++L E++ + +P V VV
Sbjct: 5195 SSPE-ARMYKTGDLARWLPDGNIDYLGRNDFQVKVRGFRIELGEIESRLMQLPGVQEAVV 5253
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A++ P+A ++ + +L L +YM+P + ++T P+ NGK+
Sbjct: 5254 AAREDIPGDTRLVAYLRSQPDAELNPTELRQQLAEHLAEYMVPSAFVTLDTFPLTPNGKI 5313
Score = 107 bits (258), Expect = 1e-22
Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD + V G GE+ + G +ARGY+ D RFI +P +
Sbjct: 6220 VPIGRPIANTQLYILDTLGQPVPLGVAGELHIGGVGVARGYLNRPDLTAERFIPDPFSNQ 6279
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A+LY+TGD L G + Y GR D QVK+RG R++L E++ + P V VV+
Sbjct: 6280 HG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVA 6338
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A++ P + + +L++ L DYMIP + ++T P+ NGK+
Sbjct: 6339 REDSPGDTRLVAYLCPQPSIELMPAELRQQLSTHLADYMIPSAFVMLDTFPLTPNGKL 6396
Score = 103 bits (248), Expect = 2e-21
Identities = 61/176 (34%), Positives = 96/176 (54%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+ + YLLD + + V G GE+ + G +ARGY+ D RFI +P + P
Sbjct: 825 IGRPLPDLRAYLLDPHGQPVPVGVAGELYIGGAGVARGYLNRPDLTAERFIVDPFSDSPA 884
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LY+TGD L G + Y GR D QVK+RG R++L E++ + P V VVL
Sbjct: 885 -TRLYKTGDLARWLPDGTLDYLGRNDFQVKVRGFRIELGEIESRLVQCPGVQEAVVLARE 943
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A++ P+A + ++ +L++ L DYMIP + +E P+ NGK+
Sbjct: 944 DVPGDTRLVAYIQPQPKAVLEPADLRQQLSTHLADYMIPAAFVTLEAFPLTPNGKL 999
Score = 101 bits (243), Expect = 8e-21
Identities = 57/178 (32%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI N +VY+LD + G GE+ + G +ARGY+ + RFI +P++
Sbjct: 1902 LPIGKPIDNTHVYILDAKGQLAPLGVAGEMYLGGVGIARGYLNRPELTAERFIPDPYSDQ 1961
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++Y+TGD G L G I Y GR D Q+K+RG R++ E++ + V + VV+
Sbjct: 1962 PG-ARMYKTGDLGRWLADGNIEYLGRNDFQIKLRGFRIEPGEIEARLMGCSGVQDAVVIV 2020
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ ++A++ + A + + +L+ L +YM+P + +E P+ NGK+
Sbjct: 2021 REDNPNDKRLVAYIRPHVGAEIEPAALRLQLSQHLAEYMLPAAFVTLEQFPLTPNGKL 2078
Score = 101 bits (243), Expect = 8e-21
Identities = 60/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD + V G GE+ + G +ARGY+ D RFI +P
Sbjct: 2981 VPIGRPIANTQLYILDTLDQPVPLGVAGELHIGGVGVARGYLNRPDLTAERFIPDPFINQ 3040
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LY+TGD L G + Y GR D QVK+RG R++L E++ + P V VV+
Sbjct: 3041 PG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVA 3099
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A++ P ++ +L L +YM+P + ++ P+ NGK+
Sbjct: 3100 REDSPGDTRLVAYLCPQPGITPDPADLRQQLGQHLAEYMVPGAFVTLDAFPLTPNGKL 3157
Score = 99.5 bits (237), Expect = 4e-20
Identities = 56/176 (31%), Positives = 91/176 (51%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P++N +Y+LD + V G GE+ + G +ARGY+ + FI +P P+
Sbjct: 4057 IGRPLANTRIYILDPQGKLVPIGATGEIHIGGVGVARGYLNRPELTAEHFIADPFTDDPD 4116
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LY+TGD G L+ G I Y GR D QVK+RG R++L E++ + V V +
Sbjct: 4117 -ARLYKTGDLGRWLNDGNIDYLGRNDFQVKVRGFRIELGEIEARLIQCSGVKEAVAIARE 4175
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A++ P + + +L L +YM+P + +E P+ NGK+
Sbjct: 4176 DTPGETRLVAYLIAQPGVELVPAELRQQLAHHLAEYMVPSAFVTMEAFPLTPNGKL 4231
>UniRef50_Q0LIS9 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1816
Score = 117 bits (282), Expect = 2e-25
Identities = 65/179 (36%), Positives = 101/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVP+G P+ N +Y+LD M+ +G PGE+ V G + RGY+ D RF+ NP +T
Sbjct: 817 TVPLGRPLGNVQIYVLDRRMQPTPQGVPGELYVGGAGVGRGYIGRPDLTAERFVPNPFST 876
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A+LYR+GD G I + GR D QVKIRG+RV+L E++ A+ V N VV+
Sbjct: 877 EAG-ARLYRSGDLVRYQPDGAIEFLGRIDLQVKIRGYRVELSEIETAIQAQAQVANSVVI 935
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A++ ++ +I L +SL DYM+P +E++ +P+ NGK+
Sbjct: 936 LREDTPGDKRLVAYIVPEAGQSLNIGSIREALRNSLPDYMVPTAFVELDGLPLNPNGKI 994
>UniRef50_Q4KCD8 Cluster: Nonribosomal peptide synthase; n=2;
cellular organisms|Rep: Nonribosomal peptide synthase -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 6675
Score = 116 bits (280), Expect = 3e-25
Identities = 66/177 (37%), Positives = 102/177 (57%), Gaps = 4/177 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI N +++LD V G+ GE+C+ G LARGY+ + +FI +P
Sbjct: 356 VPIGRPIDNIQIHILDAESHPVPIGQTGELCIGGVGLARGYLNRPELTAEKFIRDPFCAQ 415
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+ A+LYRTGD LD G I GR DSQVK+RG R++L E+++ + + P + + VVL
Sbjct: 416 PD-ARLYRTGDEARFLDDGQIEVLGRFDSQVKLRGFRIELGEIENTLKSHPGISDAVVLV 474
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGK 542
S +P+++A+V + K I + + L +YM P ++ +E +PV +GK
Sbjct: 475 QDPGSEDPKLVAYVVAQ---GLDKKTIRDFVKARLPEYMTPNRVQFVEQIPVTAHGK 528
>UniRef50_Q1DBW4 Cluster: Non-ribosomal peptide synthetase; n=3;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Myxococcus xanthus (strain DK 1622)
Length = 5544
Score = 116 bits (280), Expect = 3e-25
Identities = 68/179 (37%), Positives = 100/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T PIG PIS ++LLDE++ V G PG V + G ARGY+ D RFI +P T
Sbjct: 4992 TFPIGRPISRVRIHLLDEHLEPVLPGLPGRVYIGGAAPARGYLGAPDMTAERFIPDPFAT 5051
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A++Y TGD +L G + + GRAD Q+KIRG RV+L E++ + P V+ VVL
Sbjct: 5052 EPG-ARMYHTGDLARMLPDGRLRFLGRADHQIKIRGFRVELAEIEACLRQFPGVEEAVVL 5110
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
S ++ AF+ P+ + A + + + L YM+P ++ +E +P+ NGKV
Sbjct: 5111 ARAGGSGQTQLQAFLQAPPQ-HVRADALREHVAARLPSYMVPAALVVLEALPINANGKV 5168
Score = 113 bits (273), Expect = 2e-24
Identities = 66/178 (37%), Positives = 104/178 (58%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD +R V G PGE+ + G +ARGY R + RF+ +P ++
Sbjct: 3934 VPIGRPIANTRLYVLDAALRPVPAGVPGELYIGGEGVARGYWRRPELTAERFVPDPFSSV 3993
Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YRTGD + V+ Y GR D QVK+RGHRV+ EV+ A+ +P V + VV+
Sbjct: 3994 PG-ARMYRTGDRVRLRPSDVLEYLGRVDFQVKVRGHRVEPGEVEAALIELPGVASAVVVL 4052
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++ P ++ +VT +A + + A L L +M+P ++ + +P+ NGKV
Sbjct: 4053 REDGTTGPRLVGYVT-GHDAMPETEPLRASLAQRLPAHMVPSALVALAQLPLTANGKV 4109
Score = 96.7 bits (230), Expect = 3e-19
Identities = 64/179 (35%), Positives = 103/179 (57%), Gaps = 6/179 (3%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG P +N VY+LD+ ++ V G GE+ + G +ARGYV D RF+ +P + P
Sbjct: 774 PIGTPKANMEVYVLDDALQPVPVGIVGELYLGGLGVARGYVGRADLTAERFVPHPFSATP 833
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LYR+GD G L GV+ + RAD QVK+RG R++L EV+ A++++P V + V
Sbjct: 834 G-ARLYRSGDLGRWLPDGVLQFVSRADLQVKVRGMRIELGEVEAALASLPGVRSAAVTVQ 892
Query: 378 GVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQ--VIEIETVPVLVNGKV 545
S+ + A+V +P+A +++A L L +M+P V+ + +P+ GK+
Sbjct: 893 RRGPSDSWLAAWVVPASPDA--DVHSLQAALARLLPAFMLPSRWVLRAQ-LPLTSTGKL 948
Score = 95.9 bits (228), Expect = 5e-19
Identities = 62/180 (34%), Positives = 101/180 (56%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+ PIG P +N VY+LD+ ++ + G PGE+ + G + RGYV D RFI +P +T
Sbjct: 1832 STPIGTPKANLEVYVLDDALQPLPPGVPGELYIGGTGVGRGYVGRADLTAERFIPHPFST 1891
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LYRTGD G + G + + GR D QVK+RG R++L EV+ A++++P V + V
Sbjct: 1892 MPG-ARLYRTGDRGRWNADGTLGFLGRVDFQVKVRGMRIELGEVEAALASLPGVRSAAVT 1950
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ--VIEIETVPVLVNGKV 545
S+ + A+V + +++A L L +M+P V+ + +P+ GK+
Sbjct: 1951 VQRRGPSDSWLAAWV-VPASPDTDVHSLQAALARLLPAFMLPSRWVLRAQ-LPLTSTGKL 2008
Score = 77.4 bits (182), Expect = 2e-13
Identities = 57/178 (32%), Positives = 90/178 (50%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V +G P+ +Y+LD N V G PGE+ + G L RGY D RFI + +
Sbjct: 2877 VRLGRPLDRCRLYVLDANGAPVPPGVPGELYIGGTCLGRGYRDRPDLTAERFIPDAFSGR 2936
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD + G + + GR D QVK+RG RV+L+EV+ A+ P V V+
Sbjct: 2937 EG-GRLYRTGDRVRWNGDGSLGFLGRTDFQVKVRGVRVELEEVEAALLRQPGVRQASVVV 2995
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIET-VPVLVNGKV 545
G + + + AF+ + A + L+ +L + ++P + T +P+ +GKV
Sbjct: 2996 RGTQ-RDARLEAFLVLEGTAAGVESRLREGLSRALPEALVPSRFTVLTALPMTTSGKV 3052
>UniRef50_O68006 Cluster: Bacitracin synthetase 1 (BA1) [Includes:
ATP-dependent isoleucine adenylase (IleA) (Isoleucine
activase); ATP-dependent cysteine adenylase (CysA)
(Cysteine activase); ATP-dependent leucine adenylase
(LeuA) (Leucine activase); ATP-dependent glutamate
adenylase (GluA) (Glutamate activase); ATP-dependent
isoleucine adenylase (IleA) (Isoleucine activase);
Glutamate racemase (EC 5.1.1.3)]; n=7; cellular
organisms|Rep: Bacitracin synthetase 1 (BA1) [Includes:
ATP-dependent isoleucine adenylase (IleA) (Isoleucine
activase); ATP-dependent cysteine adenylase (CysA)
(Cysteine activase); ATP-dependent leucine adenylase
(LeuA) (Leucine activase); ATP-dependent glutamate
adenylase (GluA) (Glutamate activase); ATP-dependent
isoleucine adenylase (IleA) (Isoleucine activase);
Glutamate racemase (EC 5.1.1.3)] - Bacillus licheniformis
Length = 5255
Score = 116 bits (280), Expect = 3e-25
Identities = 68/178 (38%), Positives = 105/178 (58%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI N VY+L+++++ G GE+C+AG LARGYV + +FI NP
Sbjct: 2424 IPIGKPIDNVKVYILNKDLQLCPLGASGELCIAGEGLARGYVNRPELTREKFIGNPF--V 2481
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD +L G I + GR D QVKIRG+R++ E+++ + ++ V+
Sbjct: 2482 PG-ERMYRTGDLAKMLPDGNIQFLGRVDQQVKIRGYRIEPGEIENRLLKYEKIEEAAVIA 2540
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+P + A+VT+ E + + I A L SL DYMIPQ ++++ +P+ VNGKV
Sbjct: 2541 REDGDHDPYLCAYVTVKKE--VEPEKIRAFLKKSLPDYMIPQYFVQLDGLPLTVNGKV 2596
Score = 111 bits (266), Expect = 1e-23
Identities = 66/179 (36%), Positives = 103/179 (57%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+PIG P++N V ++DE + V G PGE+C+AG L++GY+ ++ +FI PH
Sbjct: 346 TIPIGSPLANTSVLIMDEAGKLVPIGVPGELCIAGDGLSKGYLNREELTAEKFI--PHPF 403
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +LY+TGD L G I + GR D QVKIRG R++L E++ + ++ +V
Sbjct: 404 IPG-ERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVT 462
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E S P I A++T N E +S ++ L L +YMIP ++++ +P+ NGKV
Sbjct: 463 VREDEESRPYICAYITANRE--ISLDELKGFLGEKLPEYMIPAYFVKLDKLPLTKNGKV 519
Score = 111 bits (266), Expect = 1e-23
Identities = 66/179 (36%), Positives = 103/179 (57%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+PIG P++N V ++DE + + G PGE+C+AG L++GY+ ++ +FI PH
Sbjct: 4973 TIPIGSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFI--PHPF 5030
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +LY+TGD L G I + GR D QVKIRG R++L E++ + ++ +V
Sbjct: 5031 IPG-ERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVT 5089
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E S P I A++T N E +S ++ L L DYMIP ++++ +P+ NGKV
Sbjct: 5090 VREDEESRPYICAYITANRE--ISLDELKGFLGEKLPDYMIPAYFVKMDKLPLTKNGKV 5146
Score = 110 bits (264), Expect = 2e-23
Identities = 61/179 (34%), Positives = 102/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNT 194
++P G P++N +Y+L++N + G GE+ + G +A GY+ K H FI
Sbjct: 1385 SIPYGKPLANQKIYVLNQNKQLCPVGVEGELYIGGAGVASGYIHDQEKTEHSFIQ----- 1439
Query: 195 HPNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
H +Y+TGD+G+L + G + + GR DSQVKIRG+RV++ E+++ + + + V+
Sbjct: 1440 HQELGYIYKTGDYGVLKEDGYVEFLGRKDSQVKIRGYRVEMGEIENTLVSHQEITKASVI 1499
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
Y + AFV E +S +++ L +L DYMIP + ++IE +P+ VNGKV
Sbjct: 1500 DYTSPDGIKNLYAFVV--AENAISQLDVKEFLQKTLPDYMIPAKFVQIEEIPLTVNGKV 1556
Score = 105 bits (252), Expect = 7e-22
Identities = 60/179 (33%), Positives = 103/179 (57%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++PIG P+ N +Y++D+ +R + G GE+C+AG +ARGYV + +F+ +P
Sbjct: 3464 SIPIGRPLLNTSIYIVDKELRPLPVGIAGELCIAGEGVARGYVNRPELTAEKFVDHPF-- 3521
Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P K+Y+TGD + L G I + GRAD QVKIRG+R++L EV+ + T + V+
Sbjct: 3522 EPG-KKMYKTGDLAMWLPDGQIEFLGRADHQVKIRGYRIELGEVEQQLLTHEKIKEAAVI 3580
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++ N + A++ + E + A ++ L + DYMIP ++++ +P +GKV
Sbjct: 3581 AGKDQNGNSYLCAYIASDKE--LPAADVRQFLEREMPDYMIPSYFVKLDRLPRTPSGKV 3637
>UniRef50_Q2VQ15 Cluster: Nonribosomal peptide synthetase C; n=3;
Brevibacillus texasporus|Rep: Nonribosomal peptide
synthetase C - Brevibacillus texasporus
Length = 4617
Score = 116 bits (279), Expect = 4e-25
Identities = 64/178 (35%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P++N VY+L+EN + G PGE+CV G +ARGY+ + RF+ NP
Sbjct: 1811 VPIGRPLNNTSVYILNENNQPQPIGVPGELCVGGAGIARGYLNRPELTAERFVDNPFLVG 1870
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD L G I Y GR D QVKIRGHR++L E++ ++ P + V++
Sbjct: 1871 D---RMYRTGDMARFLPDGNIEYIGRMDEQVKIRGHRIELGEIEKSLLEYPAISEAVLVA 1927
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E + + A+V + + + + +L +YM+P +E+E +P+ NGKV
Sbjct: 1928 KRDEQGHSYLCAYVVSTDQ--WTVAKVRQHILEALPEYMVPSYFVELEKLPLTSNGKV 1983
Score = 112 bits (269), Expect = 6e-24
Identities = 63/178 (35%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P++N VY+L+EN + G PGE+CV G +ARGY+ + RF+ NP +
Sbjct: 2846 VPIGRPLNNTSVYVLNENNQLQPIGVPGELCVGGAGIARGYLNRPELTAERFVENPFVSG 2905
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD L G + Y GR D QVK+RG+R++L E++ + P + V+L
Sbjct: 2906 D---RMYRTGDLARWLPDGSMEYLGRMDEQVKVRGYRIELGEIETRLLEHPSISAAVLLA 2962
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E + + A++ N + + L+ +L +YM+P +E+E +P NGKV
Sbjct: 2963 KQDEQGHSYLCAYIVAN--GVWTVAELRKHLSEALPEYMVPTYFVELEQIPFTSNGKV 3018
Score = 97.9 bits (233), Expect = 1e-19
Identities = 60/179 (33%), Positives = 93/179 (51%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PI+N Y+++ + + G GE+C+ G +A GY+ + F+ NP
Sbjct: 775 SVPIGRPINNTKAYIVNTDGQPQPIGVVGELCIGGEGVACGYLNRPELTKKHFVDNPFVL 834
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
++Y TGD L G I Y GR D QVKIRGHR++L E++ + P + V+L
Sbjct: 835 GE---RMYCTGDLARFLPDGNIEYIGRMDEQVKIRGHRIELGEIEKVLLQHPAISETVLL 891
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E + + A++ + + + L SL +YM+P IEIE +P+ NGKV
Sbjct: 892 AKRDEQGHSYLCAYIV--GQVFWTVTELRQHLMESLPEYMVPSYFIEIEKLPLTANGKV 948
Score = 91.1 bits (216), Expect = 2e-17
Identities = 60/176 (34%), Positives = 88/176 (50%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPHNTHPN 203
IG P+ N Y+++ N + G PGE+C+ G +A GY + R F+ NP
Sbjct: 3874 IGKPVLNKKAYIINPNYQLQPIGVPGELCIGGVGIAPGYWNRPELTREKFVDNPF---AQ 3930
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++Y+TGD L G I + GR D QVKIRGHR++L E++ + V VVL
Sbjct: 3931 GERMYKTGDLVRWLPDGNIEFLGRIDDQVKIRGHRIELGEIETRLLEHEQVIEAVVLARE 3990
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E + A++ E + + L +L DYMIP IE+E P+ +GKV
Sbjct: 3991 DEQGQAYLCAYLVAADE--WTVAELRKHLGKTLPDYMIPAYFIELEEFPLTPSGKV 4044
>UniRef50_Q4ZT67 Cluster: Amino acid adenylation; n=15; Bacteria|Rep:
Amino acid adenylation - Pseudomonas syringae pv.
syringae (strain B728a)
Length = 13537
Score = 116 bits (278), Expect = 5e-25
Identities = 65/178 (36%), Positives = 104/178 (58%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTH 197
+PIG PI N+ VY+LD + V G GE+ + G +A+GY+ + + +F+ NP +
Sbjct: 855 IPIGRPIGNSQVYVLDTLRQPVAVGVAGELYIGGQGVAKGYLNRPELNATQFVANPFSDD 914
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A LYRTGD G + G++ Y GR D QVKIRG R++L E++ + P V VVL
Sbjct: 915 AG-ALLYRTGDLGRWNADGIVEYLGRNDDQVKIRGFRIELGEIEARLVECPGVREAVVLA 973
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
ES++ ++A+V + +SA + EL +SL +YM+P + +++ P+ NGK+
Sbjct: 974 RQDESAHKRLVAYVVGEENSALSAVELRRELAASLAEYMVPSAFMVLDSFPLTANGKL 1031
Score = 111 bits (267), Expect = 1e-23
Identities = 64/177 (36%), Positives = 97/177 (54%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+ N YLLDE + V G GE+ + G +ARGY+ D RF+ +P + P
Sbjct: 1929 IGKPVGNTRFYLLDEQQQPVPLGVAGEIYIGGAGVARGYLNRDDLTAERFLLDPFSQQPA 1988
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD G L G I Y GR D QVKIRG R++L E+D ++ P V VV
Sbjct: 1989 -ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTARE 2047
Query: 381 VESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ T ++ + N+ + L L +YM+P + + +E +P+ NGK+
Sbjct: 2048 DIPGDKRLVAYYTLVSGHTSVDIDNLRSHLQEKLPEYMVPAIYVLLEAMPLTPNGKL 2104
Score = 110 bits (265), Expect = 2e-23
Identities = 59/176 (33%), Positives = 101/176 (57%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTHPN 203
IG P++N +YLLDE+ + V G GE+ + G +ARGY+ ++ + RF+ +P + P+
Sbjct: 10575 IGKPMANTRIYLLDEHQQPVPYGVAGEIFIGGDGVARGYLNLEEVNAERFLADPFSNSPD 10634
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++Y+TGD + G I Y GR D QVK+RG R++L E++ + V VV+
Sbjct: 10635 -ARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCKGVKEAVVIARE 10693
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+V P+A + A ++ AEL L +YM+P + ++ +P+ N K+
Sbjct: 10694 DNPGEKRLVAYVIAQPQANLDAASLRAELAPQLAEYMLPSAFVLLDALPLTPNRKL 10749
Score = 110 bits (264), Expect = 2e-23
Identities = 67/177 (37%), Positives = 97/177 (54%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200
PIG I + +Y+LD V G GE+ V G +ARGY+ + RFI NP NT P
Sbjct: 4094 PIGRRIPDLQLYVLDARGEPVPVGVVGELYVGGAGVARGYLNREALTAERFIDNPFNTAP 4153
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LYRTGD G L G + Y GR D QVKIRG R++L E++ + V + +VL
Sbjct: 4154 G-ARLYRTGDLGRWLADGSLEYLGRNDEQVKIRGFRIELGEIEAQLVACDGVQDAMVLVR 4212
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E + ++A+V A + A ++ +L SL +YM+P + +E P+ NGK+
Sbjct: 4213 EDEPGDKRLVAYVIGTAGAELDATHLREQLRLSLAEYMLPSAFVSLEAFPLTANGKL 4269
Score = 107 bits (257), Expect = 2e-22
Identities = 63/177 (35%), Positives = 98/177 (55%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200
PIGV I + +Y+LD V G GE+ V G +ARGY+ + RF+ NP + P
Sbjct: 5181 PIGVRIPDLQLYVLDARREPVPVGVVGELYVGGAGVARGYLNREALTAERFLANPFSKEP 5240
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LYRTGD G + G + Y GR D QVKIRG R++L E+ ++ V +VL
Sbjct: 5241 Q-ARLYRTGDLGRWMADGSLDYLGRNDDQVKIRGFRIELGEIQAVLAACNTVREALVLVR 5299
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+V P + A ++ A+L SL D+M+P + +++ P+ NGK+
Sbjct: 5300 EDQPGDKRLVAYVIAAPGHEIVAADLRAQLLLSLADHMVPSAFVALDSFPLTANGKL 5356
Score = 107 bits (257), Expect = 2e-22
Identities = 64/177 (36%), Positives = 96/177 (54%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+ N YLLDE + V G GE+ + G +ARGY+ D RF+ +P + +P
Sbjct: 7346 IGKPVGNTQFYLLDEQQQPVPLGVSGEIYIGGAGVARGYLNRDDLTAERFLKDPFSQNPA 7405
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD G L G I Y GR D QVKIRG R++L E+D ++ P V VV
Sbjct: 7406 -ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTARE 7464
Query: 381 VESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A+ T++ A + ++ L L YMIP + ++ +P+ NGK+
Sbjct: 7465 DVPGDKRLVAYYTLSAGHASVDIDSLRGWLQEQLPAYMIPVAYVLLDALPLTPNGKL 7521
Score = 107 bits (257), Expect = 2e-22
Identities = 63/178 (35%), Positives = 102/178 (57%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200
PIG I + +Y+LD V G GE+ V G +ARGY+ + RF+ NP + H
Sbjct: 8433 PIGRRIPDLQLYVLDARGEPVPVGVVGELYVGGAGVARGYLNREALTAERFLDNPFS-HT 8491
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A++YRTGD G L G + Y GR D QVKIRG R++L E++ ++ P V + VVLC
Sbjct: 8492 ADARMYRTGDLGRWLADGSLEYLGRNDEQVKIRGFRIELGEIEARLAEYPDVRDAVVLCR 8551
Query: 378 GVESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+VT PE+ + +++ L +L ++M+P ++++ +P+ NGK+
Sbjct: 8552 EDVPGDKRLVAYVTAQQPESLLDIESLREHLQGALPEHMVPAAYVQLDELPLTANGKL 8609
Score = 107 bits (256), Expect = 2e-22
Identities = 63/177 (35%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+ N YLLDE + V G GE+ + G +ARGY+ D RF+ +P + P
Sbjct: 9506 IGKPVGNTQFYLLDEQQQPVPLGVAGEIYIGGAGVARGYLNRDDLTAERFVKDPFSPQPA 9565
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD G L G I Y GR D QVKIRG R++L E+D ++ P + VV
Sbjct: 9566 -ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAIHEAVVAARE 9624
Query: 381 VESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A+ T++ A + ++ L L YMIP + ++ +P+ NGK+
Sbjct: 9625 DVPGDKRLVAYYTLSAGHASVDIDSLRGWLQEQLPAYMIPVAYVLLDALPLTPNGKL 9681
Score = 106 bits (255), Expect = 3e-22
Identities = 58/176 (32%), Positives = 100/176 (56%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTHPN 203
IG P++N +YLLD + + V G GE+ + G +ARGY+ ++ + RF+ +P + P
Sbjct: 11643 IGKPMANTRIYLLDAHQQPVPYGVAGEIFIGGDGVARGYLNLEEVNAERFLADPFSNSPE 11702
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++Y+TGD + G I Y GR D QVK+RG R++L E++ + V VV+
Sbjct: 11703 -ARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCTGVKEAVVIARE 11761
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V P+A + A ++ AEL L +YM+P + ++ +P+ N K+
Sbjct: 11762 DTPGDKRLVAYVVGQPQASLDAASLHAELAPQLAEYMLPSAFVILDALPLTPNRKL 11817
Score = 103 bits (248), Expect = 2e-21
Identities = 62/177 (35%), Positives = 96/177 (54%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+ N YLLDE + V G GE+ + G +ARGY+ + RF+ +P + P
Sbjct: 3006 IGKPVGNTQFYLLDEQQQPVPLGVAGEIYIGGAGVARGYLNRDELTAERFLTDPFSQQPA 3065
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD G L G I Y GR D QVKIRG R++L E+D ++ P V VV
Sbjct: 3066 -ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTARE 3124
Query: 381 VESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ T++ A + + ++ L L +MIP + ++ +P+ NGK+
Sbjct: 3125 DIPGDKRLVAYYTLSAGHASVDSDSLRGWLQEQLPAHMIPAAYVLLDAMPLTPNGKL 3181
Score = 103 bits (248), Expect = 2e-21
Identities = 62/180 (34%), Positives = 101/180 (56%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PI+N +++LD + G GE+ + G +ARGY+ D RFI +P ++
Sbjct: 6268 SVPIGRPIANIQMHVLDALGQLQPLGVAGELHIGGIGVARGYLNQPDLSAERFIADPFSS 6327
Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LY+TGD G L G + Y GR D QVKIRG R+++ E++ A++ P V VV
Sbjct: 6328 DPQ-ARLYKTGDVGRWLANGALEYLGRNDFQVKIRGLRIEIGEIEAALAKHPAVHEAVVT 6386
Query: 372 CYGVESSNPEILAFVTINPE-ARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ T + E + + + L L +YM+P + + +E +P+ NGK+
Sbjct: 6387 AREDIPGDKRLVAYYTQSAEHTAVDIETLRGHLQQQLPEYMVPAIYVLLEAMPLTSNGKL 6446
Score = 98.3 bits (234), Expect = 1e-19
Identities = 62/181 (34%), Positives = 99/181 (54%), Gaps = 5/181 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
L++PIG P +N +YLLD V G GE+ + G +A GY+ + RF +P +
Sbjct: 12692 LSLPIGKPNANVRIYLLDVCGEPVPMGSVGEIYIGGVGVALGYLNRPELSAERFSDDPFS 12751
Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
A+LYRTGD L G + Y R D QVK+RG RV+L EV+ ++ V N VV
Sbjct: 12752 QQAG-ARLYRTGDLARWLPDGNLEYLARNDGQVKVRGFRVELGEVESSLHGCDGVRNSVV 12810
Query: 369 LCYGVESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542
+ + ++A+ T++ + + + A+L++ L +YM+P V I + +P+ +NGK
Sbjct: 12811 VAREDSPGDTRLVAYYTVHADVEAPEPEALRAQLSAGLPEYMVPSVFICLPDLPLTLNGK 12870
Query: 543 V 545
V
Sbjct: 12871 V 12871
>UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2;
Cystobacterineae|Rep: Non-ribosomal peptide synthase -
Stigmatella aurantiaca DW4/3-1
Length = 1443
Score = 116 bits (278), Expect = 5e-25
Identities = 71/185 (38%), Positives = 104/185 (56%), Gaps = 11/185 (5%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI N +Y+LD + + V G PGE+ + G LARGY+R D RFI NP +
Sbjct: 847 IPIGRPIDNTQLYILDRHRQPVPIGVPGELHIGGTGLARGYLRRPDLTAERFIPNPFQSE 906
Query: 198 PNFA---KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
+ + +LYRTGD L G I + GR DSQ+KIRGHRV+ E++ A++ P V
Sbjct: 907 TSGSGGDRLYRTGDLARYLPDGRIEFLGRVDSQLKIRGHRVEAGEIEAALARHPRVVQAA 966
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAE----LTSSLTDYMIPQVIEI-ETVPVL 530
V+ V +S P ++A+V A A ++ E L + DYMIP E+ + +P+
Sbjct: 967 VVLRHVPNSPPRLVAYVQAKALAEGDAAVLKEEFRKFLRGQIPDYMIPGAFEVLDELPLT 1026
Query: 531 VNGKV 545
+GK+
Sbjct: 1027 PSGKI 1031
>UniRef50_UPI000038CB2F Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal
peptide synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 918
Score = 115 bits (277), Expect = 6e-25
Identities = 62/177 (35%), Positives = 104/177 (58%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNTHP 200
PIG PI+N +++LD+N++ V GE GE+ + G LARGY+ + +FI NP ++ P
Sbjct: 358 PIGRPITNAEIHILDDNLQPVPAGESGELHIGGIGLARGYLNRPELTIDKFIFNPFSSEP 417
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LY+TGD L G I + GR D QVKIRG R++L E++ + P + +V+
Sbjct: 418 G-ARLYKTGDLARYLSDGNIEFLGRIDDQVKIRGFRIELGEIEAILGQHPALTQTLVIAR 476
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + +++A++ + E S + L S L +YM+P + ++T+P+ NGK+
Sbjct: 477 DDVNGDKQLVAYIVASAEQIPSRVELRRFLQSQLPEYMVPAYFVFLDTLPLNPNGKI 533
>UniRef50_Q93H59 Cluster: Non-ribosimal peptide synthetase; n=1;
Streptomyces avermitilis|Rep: Non-ribosimal peptide
synthetase - Streptomyces avermitilis
Length = 1709
Score = 115 bits (277), Expect = 6e-25
Identities = 68/178 (38%), Positives = 100/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG P+ N VY+LD ++ V G GE+ V G +ARGY D RF+ +P+ T
Sbjct: 1406 LPIGRPLPNMRVYVLDPALQPVPVGVAGELYVGGTGVARGYANRPDLTADRFLPDPYGTG 1465
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YRTGD L G + + GR D QVKIRG+RV+L E+ ++ P V + VV
Sbjct: 1466 PG-ARMYRTGDLVRHLPDGNVAFLGRVDDQVKIRGYRVELGEIQAVLTAHPAVRDAVVTV 1524
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545
+ E+ P + A V + +A ++ A + L +YMIP ++T+PV NGKV
Sbjct: 1525 HRPENGEPTLAAHV-VPADAAAPLPDLAAHCAARLPEYMIPATFTALDTIPVNANGKV 1581
Score = 94.3 bits (224), Expect = 2e-18
Identities = 61/178 (34%), Positives = 88/178 (49%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P+ V +L N V G PGE+ G +ARGY D RF+ +P+ T
Sbjct: 317 VPIGRPLPGMRVLVLGPNGVPVPVGVPGELYAGGVGVARGYAGRPDLTADRFVPDPYATE 376
Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LYRTGD + Y GR D QVK+ G R++ EV+ A++ P V VV
Sbjct: 377 PG-ARLYRTGDQVRWRSDRTLEYLGRLDHQVKVNGVRIEPAEVEAALAAHPAVTGAVVTP 435
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
Y + + A++T++ EA + L L D +P + ++ P+ NGKV
Sbjct: 436 YEADGGGKRLAAYLTVSGEA--DPAGLRGFLAERLPDSHVPSFLHTLDAFPLTANGKV 491
>UniRef50_Q7N7D0 Cluster: Complete genome; segment 5/17; n=1;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 5/17 - Photorhabdus luminescens subsp.
laumondii
Length = 1060
Score = 115 bits (277), Expect = 6e-25
Identities = 73/184 (39%), Positives = 109/184 (59%), Gaps = 11/184 (5%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200
P+G PI N +YLLDE +R VR GE GE+ + G ++ARGY+ G RF+ +P +T P
Sbjct: 324 PLGKPIVNAEMYLLDEMLRPVRPGERGEIYIGGQSVARGYLYQPGLTSLRFLPDPFSTQP 383
Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN-CVVLC 374
A+++ TGD G+L G+I + GR D QVK+RGHRV+L EV+HA+ + V CVVL
Sbjct: 384 G-ARMFATGDEGVLSNDGLIEFVGRLDDQVKVRGHRVELAEVEHAIKSCQDVSAVCVVLN 442
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAE------LTSSLTDYMIP-QVIEIETVPVLV 533
+ +++A T + + + KN + E + + L YM P Q I+ E +P+
Sbjct: 443 IDSDRHVEQLVAHYTTHID-HTTHKNTDVEQAIITRVQTLLPSYMWPSQFIQHEQLPLTS 501
Query: 534 NGKV 545
+GKV
Sbjct: 502 SGKV 505
>UniRef50_Q3M5N4 Cluster: Amino acid adenylation; n=1; Anabaena
variabilis ATCC 29413|Rep: Amino acid adenylation -
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length = 1345
Score = 115 bits (277), Expect = 6e-25
Identities = 64/176 (36%), Positives = 102/176 (57%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+N +YLLD+ + V G PGE+ + G +ARGY+ + RFI NP + PN
Sbjct: 786 IGRPIANTQLYLLDDKQKLVPIGVPGELYIGGAGVARGYLNRPELTQQRFIPNPFSDEPN 845
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++LY+TGD L G I Y GR D QVKIRG R++L+E++ ++ P V+ V+
Sbjct: 846 -SRLYKTGDLARYLPDGNIEYLGRIDHQVKIRGFRIELEEIESLLAQHPLVNAVTVIARE 904
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++ ++ +A S++ + L S L +YMIP + +E +P+ +GKV
Sbjct: 905 DQPGDKRLVGYIVPKEQAPTSSE-LRQFLQSKLPEYMIPSAFVMLEVIPLTTHGKV 959
>UniRef50_Q93N89 Cluster: Peptide synthetase; n=1; Streptomyces
lavendulae|Rep: Peptide synthetase - Streptomyces
lavendulae
Length = 2116
Score = 115 bits (277), Expect = 6e-25
Identities = 65/179 (36%), Positives = 106/179 (59%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+PIG P++N ++++LD+++R V G GE+ +AG LARGY++ G RF+ P
Sbjct: 298 LPIGHPLTNRHIHVLDDSLRRVAPGVTGELYIAGAGLARGYLKRAGLSAERFVACP---F 354
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ ++YRTGD D G + +AGRAD+QVKIRG RV+L EV+ A++ P V VV+
Sbjct: 355 ADGERMYRTGDLARWTDDGELAFAGRADAQVKIRGFRVELGEVEAALAAQPAVAQAVVVA 414
Query: 375 YGVESSNPEILAFVTINPEARMSAKNI-EAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ ++ P+ + ++ A L +L DYM+P + ++ +P+ VNGKV
Sbjct: 415 REDRPGEKRLVGYLV--PDGHQADSDVLRARLAQTLPDYMVPAAFVVLDALPLTVNGKV 471
Score = 90.2 bits (214), Expect = 3e-17
Identities = 59/176 (33%), Positives = 93/176 (52%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+ V++LD +R V G GE+ V G +ARGY+ HRFI +P
Sbjct: 1350 IGGPIARAGVHVLDGFLRPVPPGVTGELYVTGTGVARGYLNRPTLTAHRFIADPRTRG-- 1407
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++YRTGD G +++ GRAD QVK+RGHR++L EV+ A++ P V+ V +
Sbjct: 1408 -GRMYRTGDLVRHTHGGELVFVGRADEQVKLRGHRIELGEVEAALADHPDVEQAVAAIH- 1465
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++ +V + A + L DYM+P V+ ++ +P+ NGK+
Sbjct: 1466 ----DARLIGYVVPADGRVPDPSALRAHASRMLPDYMLPAAVVVLDELPLTPNGKL 1517
>UniRef50_Q4C3C3 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Crocosphaera watsonii WH 8501|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Crocosphaera watsonii
Length = 1518
Score = 115 bits (277), Expect = 6e-25
Identities = 67/179 (37%), Positives = 101/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVPIG P+ N +YLLDE ++ V PGE+ + G NL+RGY + RFI NP +
Sbjct: 772 TVPIGRPLDNTQIYLLDEYLQPVPLLTPGEIYIGGANLSRGYYNRPELTEERFIINPFD- 830
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LY+TGD G L G I + GR+D QVKIRG R++L E++ +S P V VV
Sbjct: 831 --QSTRLYKTGDVGRYLPDGSIEFLGRSDRQVKIRGFRIELGEIEAVLSQHPSVKQAVVT 888
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E N ++A+V + + +++ + L YM+P + + ++T+PV NGK+
Sbjct: 889 VPKDEKGNQRLVAYVVLGSH---NTDHLQDFMRIRLPQYMVPHRFVTLKTIPVTANGKI 944
>UniRef50_Q1D6A0 Cluster: Non-ribosomal peptide synthetase; n=7;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Myxococcus xanthus (strain DK 1622)
Length = 11939
Score = 115 bits (277), Expect = 6e-25
Identities = 64/185 (34%), Positives = 103/185 (55%), Gaps = 4/185 (2%)
Frame = +3
Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFI 176
Q + +VP+G PI N VY+LD +R V G PGE+C+ G + RGY+ D RF+
Sbjct: 5041 QGRVSASVPLGRPIPNARVYVLDAYLRPVPVGVPGELCIGGRTVGRGYLGRVDLTAERFV 5100
Query: 177 HNPHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353
+ + P A++YRTGD +L G + + GR D Q+K+RG+RV++ EV+ A+ P V
Sbjct: 5101 PDAYAEDPG-ARMYRTGDRARLLADGRVEFLGRTDDQLKVRGYRVEMGEVEAALERHPSV 5159
Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVL 530
VV+ + + ++ + P + + L +L DYM+PQ ++ +E +P+
Sbjct: 5160 RESVVVAHESGTDGKRLVGYAVPKPGHTLEVDALRDFLGQTLPDYMVPQALVVLEALPLT 5219
Query: 531 VNGKV 545
NGKV
Sbjct: 5220 PNGKV 5224
Score = 112 bits (270), Expect = 4e-24
Identities = 66/179 (36%), Positives = 100/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+V IG P+ N VY+LD MR V G PGE+ V G LA GYV + RF+ NP+
Sbjct: 10346 SVSIGRPVKNTVVYVLDAGMRPVPVGVPGELYVGGDGLAMGYVGRPELTAERFVPNPYG- 10404
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ +LYRTGD L G + + GRAD+QVK+RG+R++L +V+ A++ V VV+
Sbjct: 10405 --DGERLYRTGDVVRWLRNGTLEFLGRADTQVKVRGYRIELGDVEAALAQHSGVSEAVVV 10462
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+VT A + A + + + L +YM+P + +E +P+ NGKV
Sbjct: 10463 AREDGGEGKRLVAYVTAQEGATLDAGALRSHMKQRLPEYMVPSAYVVLEALPLTPNGKV 10521
Score = 111 bits (266), Expect = 1e-23
Identities = 65/179 (36%), Positives = 101/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+V IG P+ N Y+LD MR V G PGE+ V G LA GYV + RF+ NP+
Sbjct: 1866 SVSIGRPVKNTVAYVLDGVMRPVPVGVPGELYVGGDGLAVGYVGRPELTAERFVPNPYGE 1925
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V+ VV+
Sbjct: 1926 GE---RLYRTGDMVRWLGNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHGGVNEAVVV 1982
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+VT A +++ + + + L +YM+P + +E++P+ NGKV
Sbjct: 1983 AREDGGEGKRLVAYVTAQEGAELASSALRSHMKQRLPEYMVPSAYVVLESLPLTPNGKV 2041
Score = 109 bits (263), Expect = 3e-23
Identities = 64/179 (35%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+V IG P+ N VY+LD MR V G PGE+ V G LA GYV + RF+ NP+
Sbjct: 7167 SVSIGRPVKNTVVYVLDAGMRPVPVGVPGELYVGGDGLAMGYVGRPELTAERFVPNPYGE 7226
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V+ V +
Sbjct: 7227 GE---RLYRTGDVVRWLGNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHGGVNEAVAV 7283
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+VT + + + + + L +YM+P + +E +P+ NGKV
Sbjct: 7284 TREDGGEGKRLVAYVTARTGTSLESSALRSHMKQRLPEYMVPSAYVVLEALPLTPNGKV 7342
Score = 109 bits (263), Expect = 3e-23
Identities = 64/179 (35%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+V IG P+ N Y+LD MR V G PGE+ V G LA GYV + RF+ NP+
Sbjct: 9287 SVSIGRPVKNTVAYVLDMGMRPVPVGVPGELYVGGDGLAVGYVGRPELTAERFVPNPYGE 9346
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V VV+
Sbjct: 9347 GE---RLYRTGDVVRWLSNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHSGVSEAVVV 9403
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+VT + + + + + L +YM+P + +E++P+ NGKV
Sbjct: 9404 AREDGGEGKRLVAYVTARTGTSLESSALRSHMKQRLPEYMVPSAYVVLESLPLTPNGKV 9462
Score = 107 bits (256), Expect = 2e-22
Identities = 64/180 (35%), Positives = 98/180 (54%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
++V IG P+ N Y+LD MR V G PGE+ V G LA GYV + RF+ +P
Sbjct: 3983 VSVSIGRPVKNTVAYVLDAGMRPVPVGVPGELYVGGDGLAVGYVGRPELTAERFVPSPFG 4042
Query: 192 THPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
+LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V+ VV
Sbjct: 4043 EGE---RLYRTGDVVRWLGNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHGGVNEAVV 4099
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+VT A + + + + L +YM+P + +E +P+ NGKV
Sbjct: 4100 VAREDGGEGKRLVAYVTAQEGASLDTGALRSHMKQRLPEYMVPSAYVVLEALPLTPNGKV 4159
Score = 106 bits (255), Expect = 3e-22
Identities = 64/179 (35%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+V IG P+ N Y+LD MR V G PGE+ V G LA GYV + RF+ +P
Sbjct: 6107 SVSIGRPVKNTVAYVLDMGMRPVPVGVPGELYVGGDGLAVGYVGRPELTAERFVPSPFGE 6166
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A+LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V+ V +
Sbjct: 6167 G---ARLYRTGDVVRWLGNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHGGVNEAVAV 6223
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
S ++A+VT + + + + L +YM+P + +E++P+ NGKV
Sbjct: 6224 TREDGSEGKRLVAYVTAQEGVSLETGALRSHMKQRLPEYMVPSAYVVLESLPLTPNGKV 6282
Score = 105 bits (251), Expect = 9e-22
Identities = 64/180 (35%), Positives = 98/180 (54%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHN 191
++V IG P+ N Y+LD MR V G PGE+ V G LA GYV RF+ +P
Sbjct: 8227 VSVSIGRPVKNTVAYVLDAGMRPVPVGVPGELYVGGDGLAVGYVGRPALTAERFVPSPFG 8286
Query: 192 THPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
+LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V+ VV
Sbjct: 8287 EGE---RLYRTGDVVRWLRNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHGGVNEAVV 8343
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+VT A + + + L +YM+P + +E++P+ NGKV
Sbjct: 8344 VAREDGNEGKRLVAYVTAQEGASLDTGALRNHVKQRLPEYMVPSAYVVLESLPLTPNGKV 8403
Score = 102 bits (244), Expect = 6e-21
Identities = 65/178 (36%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V IG P++N +Y+LD + V G GE+ V G +ARGY+ + RF+ P
Sbjct: 809 VAIGRPLTNVRIYVLDGELEPVPAGVVGELYVGGEGVARGYLGRPELTAERFVPAPQG-- 866
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ A+LYRTGD + GV+ Y GR DSQVK+RGHR++ EV+ A+ P V +V+
Sbjct: 867 -DGARLYRTGDKARWRRDGVLEYLGRGDSQVKVRGHRIEPGEVESALLGQPGVREVLVVV 925
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+V + + A L S L +M+PQ V+ +E +P+L NGKV
Sbjct: 926 REDAPGDKRLVAYVVPRDGRLLEGGEVRAGLESRLPRFMVPQAVVVLERLPLLPNGKV 983
Score = 99.5 bits (237), Expect = 4e-20
Identities = 66/178 (37%), Positives = 96/178 (53%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI+N Y+LD + V G PGE+ V G LARGYV D RF+ + P
Sbjct: 2926 PIGRPIANTQAYVLDAQGQPVPVGVPGELFVGGDGLARGYVGRPDLTAERFVPDALGRMP 2985
Query: 201 NFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LYRTGD G + + GR D+QVK+RGHRV+ EV+ ++ P V VV+
Sbjct: 2986 G-ARLYRTGDQVRWRSGGSLEFLGRVDTQVKVRGHRVEPGEVEVVLAEHPAVHVAVVVSR 3044
Query: 378 GVESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
S+ ++A+V + + A + A L L M+P + +E++P+L +GKV
Sbjct: 3045 KDASNETRLVAYVVPGDASGAVDATALRAFLAERLPSAMVPSWFVVLESLPLLPSGKV 3102
Score = 96.3 bits (229), Expect = 4e-19
Identities = 59/176 (33%), Positives = 92/176 (52%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
+G PI Y+LD + V +G GE+ + G LARGYV + RF+ + + P
Sbjct: 11403 VGRPIEGTRAYVLDALGQPVPQGVAGELYLGGAGLARGYVDRPELTAERFVPDAFSPQPG 11462
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LYRTGD L GV+ Y GR D QVK+RG R++L E++ + P V VV+
Sbjct: 11463 -ARLYRTGDSARWLPDGVLQYLGRIDQQVKVRGFRIELGEIEAVLRRHPDVREAVVVVRD 11521
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
S ++A++ + A + + L D+M+P V+ + ++P+ NGKV
Sbjct: 11522 DGSEGRRLVAYIVPQSDRVPDATALRRFVKEGLPDFMVPSVVMVLASLPLTPNGKV 11577
>UniRef50_Q0SKF6 Cluster: Non-ribosomal peptide synthetase; n=2;
Nocardiaceae|Rep: Non-ribosomal peptide synthetase -
Rhodococcus sp. (strain RHA1)
Length = 10372
Score = 115 bits (277), Expect = 6e-25
Identities = 67/180 (37%), Positives = 104/180 (57%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
+TVPIG P+ N V++LD + V G GE+ +AG LARGY+ D RF+ NPH
Sbjct: 9807 VTVPIGRPVWNTQVHVLDSRLHPVPNGVAGELYLAGDQLARGYLNRPDLSADRFVANPHV 9866
Query: 192 THPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
++YRTGD GV+ Y GR D QVK+RG R++L E++ A+ P V VV
Sbjct: 9867 AG---GRMYRTGDLVRRRADGVLEYVGRTDFQVKLRGQRIELGEIEAALEAHPDVSQAVV 9923
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + + ++A++ + P A ++ A L++ + YMIP QV+ ++T+P+ NGK+
Sbjct: 9924 VVHRDDRGEEALVAYL-VGPRA-ADWSDVRAHLSARVPSYMIPAQVVHLDTLPLSANGKL 9981
Score = 104 bits (249), Expect = 2e-21
Identities = 61/178 (34%), Positives = 91/178 (51%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIGVP N Y+LD + V G PGE+ + G LARGY+ D RF+ NP
Sbjct: 4484 VPIGVPEWNTQAYVLDSRLHPVPVGVPGELYLGGAQLARGYLGRVDLTSDRFVANPFGRT 4543
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G ++Y GR D QVK RG R++L E++ + + P V VV
Sbjct: 4544 GE--RMYRTGDLVRWTSSGALVYIGRTDFQVKFRGQRIELGEIETVLRSHPAVTGAVVSV 4601
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
Y + ++A+V P + + + + SL YM+P I + + P+ +GK+
Sbjct: 4602 YSDTTVGDHLVAYVVGTP-GELDVAELRRQASESLPSYMVPSAITVLDEFPLNTSGKL 4658
Score = 102 bits (244), Expect = 6e-21
Identities = 63/179 (35%), Positives = 93/179 (51%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVPIGVP N VY+LD + V G GE+ +AG LARGY+ D RF+ NP
Sbjct: 1872 TVPIGVPEWNTQVYVLDSRLHPVPPGVAGELYLAGEQLARGYLGRVDLTSDRFVANPFT- 1930
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD G + Y GR D QVK RG R++L E++ + P V + VL
Sbjct: 1931 -PGL-RMYRTGDLVRWTSAGALEYIGRTDFQVKFRGQRIELGEIEFVLRAQPSVTSAAVL 1988
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + ++A+V P + + +SL YMIP ++ ++ P+ +GK+
Sbjct: 1989 VHSDPGTGDRLVAYVVPEPGHDLDTTRLRECAAASLPAYMIPAALMVVDEFPLNTSGKL 2047
Score = 99.1 bits (236), Expect = 6e-20
Identities = 62/182 (34%), Positives = 102/182 (56%), Gaps = 7/182 (3%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVPIG P N V++LD + V G GE+ +AG LARGYV D RF+ NP
Sbjct: 8743 TVPIGGPEWNTQVFVLDARLNPVPVGVAGELYLAGEQLARGYVARADLTAERFVANPFGA 8802
Query: 195 HPNFAKLYRTGD---FGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
+ ++LYRTGD + + D +GV+ Y R+D QVK+RG R++L E++ A+ + V
Sbjct: 8803 --SGSRLYRTGDVVRWHVRDSRGVLEYLERSDFQVKVRGFRIELGEIESALVSSAGVGQA 8860
Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539
VV+ + + ++ +V A + + AE+ +++ YM+P ++ + +P+ NG
Sbjct: 8861 VVVAHQHPHTGTTLIGYVVPEDGATVDFAAVLAEVGAAVPSYMVPAALVVLAQLPLTSNG 8920
Query: 540 KV 545
K+
Sbjct: 8921 KL 8922
Score = 92.3 bits (219), Expect = 7e-18
Identities = 55/178 (30%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V +G P+ N Y+LD+ + G GE+ +AG ++RGY D RF+ NP +
Sbjct: 2935 VTVGTPVWNTRAYVLDQRLHPSPAGVTGELYLAGTQVSRGYAGRPDLTAERFVANPFDA- 2993
Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD +G + Y GR D QVK+RG R++L E++ + + V VV
Sbjct: 2994 PG-TRMYRTGDRLRWTGRGELEYLGRNDFQVKLRGLRIELGEIEAVLESADSVAQAVVTV 3052
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
Y +S +++A++ R+ + + A S L +YM+P + ++ P+ +GK+
Sbjct: 3053 YSGAASE-QLVAYLVARAGTRVDIEALTAYAASRLPEYMVPDGFVTLDAFPLNASGKL 3109
Score = 87.4 bits (207), Expect = 2e-16
Identities = 58/182 (31%), Positives = 97/182 (53%), Gaps = 8/182 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V +G P + +LD +R V G GE+ V G +LARGYVR G RF+ +P T
Sbjct: 806 VTVGSPTVGVDLVVLDHRLRPVPAGVRGELYVLGSSLARGYVRRAGLTAERFVASPFGTG 865
Query: 198 PNFAKLYRTGD---FGILDKG--VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
++YRTGD + G V+ + GR+D QVKIRG R++L E+D A++ P V+
Sbjct: 866 ---GRMYRTGDVVRWVTAPDGPPVLEFLGRSDFQVKIRGFRIELGEIDAALTAHPVVEFA 922
Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539
+ Y S + ++++V P + + + + L YM+P ++ ++++P+ G
Sbjct: 923 YTVGYDDGSGSSRLVSYVLPVPATDVETRVLSEFVGERLPGYMVPSSIMMLDSLPLTPAG 982
Query: 540 KV 545
K+
Sbjct: 983 KL 984
Score = 85.4 bits (202), Expect = 8e-16
Identities = 56/180 (31%), Positives = 89/180 (49%), Gaps = 8/180 (4%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG P+ ++LD + V G PGE+ ++G LARGY + G RF+ NPH P
Sbjct: 5542 IGAPVRGVEAFVLDARLHPVSPGVPGELYISGPALARGYHQRLGLTAERFVANPHGA-PG 5600
Query: 204 FAKLYRTGDF-----GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
++YRTGD VI Y GR+D QVKIRG RV+L E+D V
Sbjct: 5601 -RRMYRTGDLVRWVESRTGTYVIEYVGRSDFQVKIRGFRVELGEIDSVFRAHSAVGFAAT 5659
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + ES ++ +V + ++ A + L +M+P ++ ++++P+ GK+
Sbjct: 5660 IAHDTESGVTALVTYVCAASGNDVDVDDLTAFVGGVLPAHMVPGSIMVLDSIPLTPAGKL 5719
Score = 81.0 bits (191), Expect = 2e-14
Identities = 55/178 (30%), Positives = 90/178 (50%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V IG P +LD +R V G PGE+ V G +LARGY+ G RF+ +P+
Sbjct: 7680 VTIGGPSRGVRALVLDGRLRPVPVGVPGELYVGGPSLARGYLGRPGLTAERFVADPYGEP 7739
Query: 198 PNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ +YRTGD + +L + GR D QVKIRG R++L E+D A++ P ++ +
Sbjct: 7740 GDL--MYRTGDLVRWRENRVLDFVGRTDHQVKIRGFRIELGEIDAALTAHPQIEYATTIG 7797
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
Y + ++A+V + + + +L YM+P V ++ +P+ GK+
Sbjct: 7798 YEHPNGETSLVAYVLPFTGEDVDRVEVANFVGRTLPAYMVPASVTLLDALPLTPAGKL 7855
Score = 77.4 bits (182), Expect = 2e-13
Identities = 60/193 (31%), Positives = 93/193 (48%), Gaps = 19/193 (9%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+ IG P+ +LD +R V G GE+ + G LARGY HRF+ +P
Sbjct: 6602 ITIGGPLPGVAAVVLDSRLRPVPVGVVGELYLLGPALARGYHERAALTAHRFVASPFEAA 6661
Query: 198 PNFAKLYRTGDF-----------GILDKGV-----ILYAGRADSQVKIRGHRVDLQEVDH 329
A++YRTGD G + G I Y GR+D QVK+RG R++L E+D
Sbjct: 6662 G--ARMYRTGDIVRWRAVHSGVTGSMTDGTFPGHAIEYLGRSDHQVKVRGLRIELGEIDA 6719
Query: 330 AVSTIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VI 506
A++ P V+ L Y + + + V + A + A L +L YM+P ++
Sbjct: 6720 ALNAHPDVEFAATLGY-ESPAETRLASHVLVGAGADRDPAALLAFLRQALPGYMVPSALV 6778
Query: 507 EIETVPVLVNGKV 545
++T+P+ NGK+
Sbjct: 6779 FLDTIPLTPNGKL 6791
>UniRef50_A7BXM0 Cluster: Non-ribosomal peptide synthetase; n=2;
Beggiatoa|Rep: Non-ribosomal peptide synthetase -
Beggiatoa sp. PS
Length = 662
Score = 115 bits (277), Expect = 6e-25
Identities = 63/180 (35%), Positives = 101/180 (56%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PI+N +Y++D + + V G GE+ + G +ARGY+ D FI NP N
Sbjct: 210 SVPIGRPIANTQIYIVDHDYQPVPIGVIGELYIGGDGVARGYLNRPDLTAETFIPNPFNQ 269
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
LY+TGD L +G I Y GR D+QV+IRG RV+L E++ ++ P V VV+
Sbjct: 270 DGKNGPLYKTGDLARYLPEGNIEYLGRIDNQVQIRGFRVELGEIEKVLTQHPAVRESVVI 329
Query: 372 CYGVESSNPEILAF-VTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
N ++A+ + + E ++ + + +L DYM+P +++ET+P+ NGK+
Sbjct: 330 VKEEPEQNQRLIAYIIPVASEDKIDISELRRFIAETLPDYMVPSFFVKMETIPLTPNGKI 389
>UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine
synthetase II) [Includes: ATP- dependent proline
adenylase (ProA) (Proline activase); ATP-dependent
phenylalanine adenylase (PheA) (Phenylalanine activase);
ATP-dependent D-phenylalanine adenylase (D-PheA)
(D-phenylalanine activase); Phenylalanine racemase
[ATP-hydrolyzing] (EC 5.1.1.11)]; n=5;
Paenibacillaceae|Rep: Tyrocidine synthetase 2 (Tyrocidine
synthetase II) [Includes: ATP- dependent proline
adenylase (ProA) (Proline activase); ATP-dependent
phenylalanine adenylase (PheA) (Phenylalanine activase);
ATP-dependent D-phenylalanine adenylase (D-PheA)
(D-phenylalanine activase); Phenylalanine racemase
[ATP-hydrolyzing] (EC 5.1.1.11)] - Brevibacillus
parabrevis
Length = 3587
Score = 115 bits (277), Expect = 6e-25
Identities = 64/176 (36%), Positives = 102/176 (57%), Gaps = 4/176 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PISN +Y+LDE ++ EG GE+ ++G N+ RGY+ + +F+ NP+ P
Sbjct: 781 PIGKPISNTGIYILDEGLQLKPEGIVGELYISGANVGRGYLHQPELTAEKFLDNPY--QP 838
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD + L G + + GR D QVKIRGHR++L E++ + P + VV+
Sbjct: 839 G-ERMYRTGDLALWLPDGQLEFLGRIDHQVKIRGHRIELGEIESRLLNHPAIKEAVVIDR 897
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542
E+ + A+V + + +S + + A L +L +YMIP + +E +PV NGK
Sbjct: 898 ADETGGKFLCAYVVL--QKALSDEEMRAYLAQALPEYMIPSFFVTLERIPVTPNGK 951
Score = 104 bits (250), Expect = 1e-21
Identities = 61/179 (34%), Positives = 96/179 (53%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+ IG PI N +Y++D+ ++ G+ GE+C++G +LARGY + +F+ NP
Sbjct: 2847 TITIGKPIQNTKLYIVDDQLQLKAPGQMGELCISGLSLARGYWNRPELTAEKFVDNPF-- 2904
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P K+YRTGD L G I Y GR D QVKIRGHRV+L EV+ + V +
Sbjct: 2905 VPG-TKMYRTGDLARWLPDGTIEYLGRIDHQVKIRGHRVELGEVESVLLRYDTVKEAAAI 2963
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + + A+ EA + + A + + L +YM+P I++E +P+ N K+
Sbjct: 2964 THEDDRGQAYLCAYYVAEGEA--TPAQLRAYMENELPNYMVPAFFIQLEKMPLTPNDKI 3020
Score = 101 bits (242), Expect = 1e-20
Identities = 55/178 (30%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+ IG PI+N +Y++D++ + + G GE+C+ G LARGY + + +F+ NP
Sbjct: 1815 ITIGRPIANTAIYIVDQHHQLLPVGVVGEICIGGHGLARGYWKKPELTAEKFVANP--AV 1872
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++Y+TGD G L G I + GR D Q+K+RG+R+++ E++ + + +V+
Sbjct: 1873 PG-ERMYKTGDLGRWLHDGTIDFIGRVDDQIKVRGYRIEVGEIEAVLLAYDQTNEAIVVA 1931
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
Y + + + A+VT + + + A L L YM+P +I+++ P+ NGKV
Sbjct: 1932 YQDDRGDSYLAAYVT--GKTAIEESELRAHLLRELPAYMVPTYLIQLDAFPLTPNGKV 1987
>UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C
[Includes: ATP-dependent valine adenylase (ValA) (Valine
activase); ATP-dependent D-valine adenylase (D-ValA)
(D-valine activase); Valine racemase [ATP-hydrolyzing]
(EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA)
(Tryptophan activase); ATP-dependent D-leucine adenylase
(D-LeuA) (D-leucine activase); Leucine racemase
[ATP-hydrolyzing] (EC 5.1.1.-); ATP- dependent
tryptophan/phenylalanine/tyrosine adenylase
(Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine
activase); ATP-dependent D-leucine adenylase (D-LeuA)
(D-leucine activase); Leucine racemase [ATP- hydrolyzing]
(EC 5.1.1.-)]; n=11; cellular organisms|Rep: Linear
gramicidin synthetase subunit C [Includes: ATP-dependent
valine adenylase (ValA) (Valine activase); ATP-dependent
D-valine adenylase (D-ValA) (D-valine activase); Valine
racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent
tryptophan adenylase (TrpA) (Tryptophan activase);
ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine
activase); Leucine racemase [ATP-hydrolyzing] (EC
5.1.1.-); ATP- dependent
tryptophan/phenylalanine/tyrosine adenylase
(Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine
activase); ATP-dependent D-leucine adenylase (D-LeuA)
(D-leucine activase); Leucine racemase [ATP- hydrolyzing]
(EC 5.1.1.-)] - Brevibacillus parabrevis
Length = 7756
Score = 115 bits (277), Expect = 6e-25
Identities = 64/177 (36%), Positives = 101/177 (57%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PISN VY+LD++ + V G GE+ + G LA GY+ + RF+ NP +
Sbjct: 781 PIGRPISNTTVYVLDKHKQPVPYGAAGELYIGGDGLALGYLNNAELTAERFVENPFDPQK 840
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++LYRTGD L G I + GR D+QVKIRG R++L EV+ A++ P V VV+
Sbjct: 841 G-SRLYRTGDLVRYLPNGTIEFIGRIDNQVKIRGFRIELGEVEAALALHPEVSETVVMAR 899
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + A+VT+ + +++A L + L +YM+P + ++ +P+ NGK+
Sbjct: 900 ENDRGEKHLTAYVTVAKDDAPEVADLQAWLKTKLPEYMVPSAYVFLDAMPLTANGKI 956
Score = 112 bits (269), Expect = 6e-24
Identities = 66/179 (36%), Positives = 102/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+ PIG P++N +Y+LD N + V G PGE+ + G LARGY + RFI +P
Sbjct: 3365 SAPIGRPLANATLYVLDANQKPVPVGVPGELYIGGKGLARGYWNRPELTAERFIAHPFGA 3424
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LYRTGD L G + + GR D+QVKIRG+R++L E++ A+S P + VV+
Sbjct: 3425 KGE--RLYRTGDLVRYLPDGNLEFLGRIDTQVKIRGYRIELGEIESALSQHPAIQEAVVI 3482
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + A++ EA+ +A+ + L +L DYMIP + ++ +P+ VNGKV
Sbjct: 3483 AW-----EQRLAAYMVAAGEAQPAAEELARYLKETLPDYMIPAGFVFMDAIPLTVNGKV 3536
Score = 111 bits (266), Expect = 1e-23
Identities = 64/177 (36%), Positives = 100/177 (56%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI+N VY+LD +++ V G PGE+ + G +ARGY + RFI +P
Sbjct: 5946 PIGRPIANTTVYVLDAHLQPVPIGVPGELYIGGKGVARGYWNRPELTAERFIADPFGQAD 6005
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+LYRTGD L+ G + + GR D QVKIRG+R++L E+++A+ P V N VV+
Sbjct: 6006 E--RLYRTGDLVRYLENGELEFLGRIDDQVKIRGYRIELGEIENALRQHPAVQNVVVIAR 6063
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + + A++ + + L S+L +YM+P + +E +P+ VNGKV
Sbjct: 6064 QEGAGDKRLAAYLVAATGQQPDEAELVRYLKSTLPEYMVPAGYVWLEKIPLTVNGKV 6120
Score = 109 bits (261), Expect = 5e-23
Identities = 65/176 (36%), Positives = 94/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI N VY+LDE + V G GE+ +AG +LARGY + D RF+ NP +
Sbjct: 7007 IGRPIDNVQVYILDEQRQPVPIGVTGELYIAGSSLARGYYKRPDLTQERFVDNPFTANRG 7066
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
AK+YRTGD L G I + GR+D QV IRG RV+L E++ + P V +VL
Sbjct: 7067 -AKMYRTGDLVRYLPDGQIEFIGRSDDQVSIRGFRVELGEIESVLYQHPAVKEAIVLARE 7125
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ A+V + + A ++ L L +YM+P + ++ +P+ NGKV
Sbjct: 7126 DMPGVKRLAAYVVVAEDDAEQADDLRGYLKEKLPEYMVPAAFVTLKALPLTPNGKV 7181
Score = 104 bits (250), Expect = 1e-21
Identities = 61/177 (34%), Positives = 95/177 (53%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PISN VY+LD+N + V G GE+ + G LA GY+ + RF+ NP +
Sbjct: 1846 PIGRPISNTTVYVLDKNRQPVPLGVAGELYIGGDGLASGYLNNPELTAERFVDNPFDPQ- 1904
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++LYRTGD L G I + GR D+QVKIRG R++L E++ A+ P V ++
Sbjct: 1905 KASRLYRTGDLVRYLPDGAIEFIGRIDNQVKIRGFRIELGEIETALLRHPAVQEAFLMVR 1964
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + A++ + + + L L +YMIP +++++ P+ NGKV
Sbjct: 1965 EDAPGDKRLAAYLVFAGGQTVEPVEMRSYLKDKLPEYMIPSAFVQMDSFPLTPNGKV 2021
Score = 99.1 bits (236), Expect = 6e-20
Identities = 66/180 (36%), Positives = 99/180 (55%), Gaps = 8/180 (4%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI N VY+LDE ++ V G GE+ +AG +LARGY+ D RFI NP+
Sbjct: 4423 IGRPIDNVQVYVLDEKLQPVPIGVAGELYIAGDSLARGYLHRPDLTRERFIANPYGQKAG 4482
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++Y+TGD L G I + GRAD QV IRG RV+L E++ A+ + P V +VL
Sbjct: 4483 -ARMYKTGDLVRYLPDGNIEFIGRADDQVSIRGFRVELGEIETALYSHPAVKETIVLVRE 4541
Query: 381 VESSNPEILAFVTINPEAR----MSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A++ + E + + A + + L L +YM+P + + +P+ NGKV
Sbjct: 4542 DMPGMKRLVAYI-VQREGQEGQAVQAGDFRSYLKELLPEYMVPAAFVFMADLPLTPNGKV 4600
>UniRef50_Q83DF1 Cluster: Peptide synthetase, putative; n=6;
Coxiella burnetii|Rep: Peptide synthetase, putative -
Coxiella burnetii
Length = 446
Score = 115 bits (276), Expect = 8e-25
Identities = 66/180 (36%), Positives = 102/180 (56%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVPIG + N+ +Y++DEN R V +GE GE+ + G ++A GY + + RFI NP +
Sbjct: 252 TVPIGQAVRNSRLYVVDENNRPVEQGEVGELLIGGASVACGYYKAPELTRERFIKNPFSA 311
Query: 195 HPNFAKLYRTGDF--GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
+ LYRTGD + DK LY GR D+QVKI G+ V+L EV++ + +++ +
Sbjct: 312 EDDI--LYRTGDLVKQLPDKS-FLYLGRIDNQVKINGYLVELNEVEYCLLRQTSIEHAYI 368
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
L E + + A+V + P+A + I L+ L +MIPQ I+ +P+ NGKV
Sbjct: 369 LAKKHEDGHQSLEAYVVLKPQATFNEAEIRNRLSQQLPQFMIPQHYYLIDRIPLTPNGKV 428
>UniRef50_Q70C47 Cluster: Polyketide non-ribosomal peptide synthase;
n=2; Xanthomonas albilineans|Rep: Polyketide
non-ribosomal peptide synthase - Xanthomonas albilineans
Length = 6879
Score = 115 bits (276), Expect = 8e-25
Identities = 69/178 (38%), Positives = 103/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG PI+N VY+LD +R V G GE+ V +ARGY G RFI +P++
Sbjct: 4087 VPIGAPIANTEVYVLDRQLRQVPIGVMGELHVHSVGMARGYWNRPGLTASRFIAHPYSEE 4146
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +LY+TGD L G + Y GR D +VK+RGHRVD ++V+ A+ P V VV
Sbjct: 4147 PG-TRLYKTGDMVRRLADGTLEYLGRQDFEVKVRGHRVDTRQVEAALRAQPAVAEAVVSG 4205
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ V+ + +++A+V SA ++ +L++ L YM+P V + +E +P L NGK+
Sbjct: 4206 HRVD-GDMQLVAYVVAREGQAPSAGELKQQLSAQLPTYMLPTVYQWLEQLPRLSNGKL 4262
Score = 115 bits (276), Expect = 8e-25
Identities = 69/178 (38%), Positives = 103/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG PI+N VY+LD +R V G GE+ V +ARGY G RFI +P++
Sbjct: 6165 VPIGAPIANTEVYVLDRQLRQVPIGVMGELHVHSVGMARGYWNRPGLTASRFIAHPYSEE 6224
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +LY+TGD L G + Y GR D +VK+RGHRVD ++V+ A+ P V VV
Sbjct: 6225 PG-TRLYKTGDMVRRLADGTLEYLGRQDFEVKVRGHRVDTRQVEAALRAQPAVAEAVVSG 6283
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ V+ + +++A+V SA ++ +L++ L YM+P V + +E +P L NGK+
Sbjct: 6284 HRVD-GDMQLVAYVVAREGQAPSAGELKQQLSAQLPTYMLPTVYQWLEQLPRLSNGKL 6340
Score = 43.2 bits (97), Expect = 0.004
Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Frame = +3
Query: 90 REGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAKLYRTGDFGILDKGVILYAG 269
R E GE+ V +ARGY+ K + N H + + +RTGD G + G + G
Sbjct: 446 RPDEIGEIWVKSPAIARGYLFAKPADQRQFNCSIRHTDDSGYFRTGDLGFIADGCLYVTG 505
Query: 270 RADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVESSNPE-ILAFVTIN 425
R + IRG ++ +++ + + + +E + E + A + +N
Sbjct: 506 RVKEVLIIRGKNHYPAHIEASIAATASPGALMPVVFSIERQDEERVAAVIAVN 558
>UniRef50_Q2VQ13 Cluster: Nonribosomal peptide synthetase E; n=1;
Brevibacillus texasporus|Rep: Nonribosomal peptide
synthetase E - Brevibacillus texasporus
Length = 2526
Score = 115 bits (276), Expect = 8e-25
Identities = 66/176 (37%), Positives = 101/176 (57%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P N Y+LD+ G PGE+CV G +ARGY+ + +F+++P+ PN
Sbjct: 766 IGTPTVNKRAYILDQYGHIQPIGVPGELCVGGEGVARGYLHRPELTDEKFVNDPYV--PN 823
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++Y+TGD L G I + GR D QVKIRG R++L E++ ++ P V VVL
Sbjct: 824 -GRMYKTGDLARWLPDGTIEFLGRMDGQVKIRGFRIELGEIEARLNQAPSVKQAVVLARS 882
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E + A++ + + ++SA + EL+ +L DYMIP I++E +PV VNGK+
Sbjct: 883 GEQKQVYLCAYLVTDNDLKVSA--LRKELSQTLPDYMIPSFFIKVEKIPVTVNGKI 936
Score = 103 bits (246), Expect = 4e-21
Identities = 62/178 (34%), Positives = 100/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+ IG P N VY+++EN + G PGE+C+AG L+RGY+ + +F++NP
Sbjct: 1789 ITIGKPFPNQKVYIINENQQLQPIGVPGELCIAGAGLSRGYLNRPELTQEKFVNNPF--A 1846
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++Y+TGD L G I YAGR D QVK+RG+RV+L EV + T P + VV+
Sbjct: 1847 PG-ERMYKTGDVARWLPDGNIEYAGRMDDQVKVRGNRVELGEVTSQLLTHPSITEAVVVP 1905
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ A+ + E +++ ++ L +L ++MIP I+++ +P+ NGKV
Sbjct: 1906 IVDTHGATTLCAYFIEDKEVKVN--DLRHHLAKALPEFMIPTYFIKVDHIPLTGNGKV 1961
>UniRef50_Q8L334 Cluster: Peptide synthetase; n=14; Nostocaceae|Rep:
Peptide synthetase - Aphanizomenon ovalisporum
Length = 1869
Score = 114 bits (275), Expect = 1e-24
Identities = 68/182 (37%), Positives = 101/182 (55%), Gaps = 8/182 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VP+G P+ N VY+LDE + V GE GE+C+ G LARGY D +FI NP T+
Sbjct: 379 VPVGRPLHNVQVYILDEAQQPVPVGEEGELCIGGIGLARGYHNLPDLTNEKFIPNPFGTN 438
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
N KLYRTGD L G I + GR D QVKIRG RV+L E++ +++ V C V+
Sbjct: 439 GNAKKLYRTGDLARYLPDGTIEHLGRIDHQVKIRGFRVELGEIESVLTSHQAVRECAVVA 498
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAEL----TSSLTDYMIP-QVIEIETVPVLVNG 539
+ + + +++ ++ +S +E L + L +YMIP + I I +P+ +G
Sbjct: 499 REI-AGHTQLVGYILAKDTPNLSFDKLEPILRQYSEAVLPEYMIPTRFINISNMPLTPSG 557
Query: 540 KV 545
K+
Sbjct: 558 KL 559
>UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain -
Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 3176
Score = 114 bits (275), Expect = 1e-24
Identities = 71/179 (39%), Positives = 100/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TV IG PI+N VY+LD+ +R V G PGE+C+AG LARGY + D +F+ +P
Sbjct: 562 TVLIGRPIANTRVYMLDDALRPVPLGVPGEICIAGDGLARGYHQRPDVTAAKFVEHP--- 618
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A++YRTGD G L G I GR D QVKIRGHRV+L E++ A++ V V+
Sbjct: 619 FPGEARIYRTGDIGRWLPDGQIQCYGRVDDQVKIRGHRVELGEIEAALTAHEDVVGAAVM 678
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ A+V A ++ ++ A L L DYM+P + I P+ NGK+
Sbjct: 679 LRESAHGVRKLAAYV--KGSANLNVADLRAFLAGKLPDYMVPSDIFPIAEFPLNANGKL 735
Score = 102 bits (245), Expect = 5e-21
Identities = 62/179 (34%), Positives = 103/179 (57%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N VY++D ++ V G GE+ + G + RGY + +FI +P +
Sbjct: 1610 VPIGRPIANTRVYIVDAQLQPVPVGVAGELLIGGTPVGRGYHGEPELSAEKFIADPFSAD 1669
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A+LYRTGD G I + GR D Q+K+RG R++ E++ A+ P VD+CVV+
Sbjct: 1670 SQ-ARLYRTGDLARYRPDGNIEFLGRIDHQIKLRGLRIEPGEIEAALREHPSVDDCVVIA 1728
Query: 375 YGVESSNPEILAFV-TINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + ++A+V T +P+ ++ L+ L DYM+P + + +E++P+L NGK+
Sbjct: 1729 -KTDGARTFLIAYVATASPD----LADLRGYLSGKLADYMVPSKFVTLESLPLLPNGKI 1782
>UniRef50_A5N8Z4 Cluster: Predicted hybrid nonribosomal peptide
synthetase/polyketide synthase; n=1; Clostridium kluyveri
DSM 555|Rep: Predicted hybrid nonribosomal peptide
synthetase/polyketide synthase - Clostridium kluyveri DSM
555
Length = 2001
Score = 114 bits (275), Expect = 1e-24
Identities = 60/178 (33%), Positives = 101/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+ IG PISN +Y++D+N + G GE+C+ G +ARGY+ KD +F +NP+ +
Sbjct: 1531 ISIGKPISNTQIYIIDKNNKLQPIGVSGELCIGGDGVARGYLNRKDLTKEKFFNNPYKVN 1590
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
K+YRTGD G + + GR D+QVKIRG+R++L E++ ++ T + CVV+
Sbjct: 1591 ---EKIYRTGDLAKWQPDGTVEFLGRIDNQVKIRGYRIELSEIEKSLGTCKGIKECVVIS 1647
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + ++A+ + E +S + + L DYMIP + I+ +P+ NGK+
Sbjct: 1648 RENSTGDKYLIAYYVADMEIGVS--KLREHMLKELPDYMIPSYFVPIKCMPLTPNGKI 1703
>UniRef50_A3YFF7 Cluster: Amino acid adenylation; n=1; Marinomonas sp.
MED121|Rep: Amino acid adenylation - Marinomonas sp.
MED121
Length = 3118
Score = 114 bits (275), Expect = 1e-24
Identities = 72/191 (37%), Positives = 107/191 (56%), Gaps = 10/191 (5%)
Frame = +3
Query: 3 QMHIF-LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRF 173
+MHI ++ IG PI NN +Y+LDE + V+ GE GE+ VAG N+ GY+ +F
Sbjct: 1425 EMHIQEKSIHIGYPIPNNRLYVLDEAKKPVKLGEIGELYVAGANVGLGYLNNPALTQLKF 1484
Query: 174 IHNPHNTHPNFAK-LYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP 347
+P H N K +Y+TGD I D G I AGRAD Q+KI G R++ E++H + +
Sbjct: 1485 TQDPFVDHQNVKKRMYQTGDLAIQRDDGAIELAGRADFQIKINGFRIEAGEIEHCILSHQ 1544
Query: 348 CVDNCVVLCYGVESSNPEILAFVTIN----PEARMSAKNIEAELTSSLTDYMIPQVI-EI 512
+ +V+ ES+ I+A++ N + KNI+A L +SL YM P +I +
Sbjct: 1545 GITQALVVQQQDESAGDLIIAYIIPNKASLSQTESLIKNIKARLATSLPTYMQPSLIMPL 1604
Query: 513 ETVPVLVNGKV 545
ET P+ NGK+
Sbjct: 1605 ETFPLTQNGKI 1615
Score = 94.3 bits (224), Expect = 2e-18
Identities = 57/180 (31%), Positives = 93/180 (51%), Gaps = 6/180 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNTH 197
VPIGV I + ++ EN + +GE GE+ ++G +LA GY+ + RF
Sbjct: 328 VPIGVAIGQTSILIIKENNKIALKGEKGELYLSGPSLAEGYLNDAVQTEKRFTFRADLGA 387
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ Y+TGD +L D + Y GR D QVKIRGHRV++ E+DH + T P +
Sbjct: 388 NSQNLWYKTGDLVVLNDNNEVDYLGRLDDQVKIRGHRVEVGEIDHYLLTHPYIKEAATFG 447
Query: 375 YGVESSNPEILAFVTINPEAR--MSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
++ +++ +N E +S ++++ L SL YM+P I I + +P+ N K+
Sbjct: 448 VSQSLGEKDLYSYLVLNQENNNALSKQDVKEYLKHSLPSYMLPHRIFITDKMPLTANQKL 507
>UniRef50_A3INW9 Cluster: Amino acid adenylation; n=1; Cyanothece sp.
CCY 0110|Rep: Amino acid adenylation - Cyanothece sp. CCY
0110
Length = 1092
Score = 114 bits (275), Expect = 1e-24
Identities = 62/179 (34%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVP+G P+ N +Y+LD ++ V G GE+ + G NL+RGY+ + RFI NP +
Sbjct: 786 TVPLGTPLPNTQMYILDRYLQPVPIGVTGELYIGGDNLSRGYLNQPELTEERFIENPFDK 845
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
KLY+TGD G I + GR+D Q+KIRG R++L EV+ + P + VV
Sbjct: 846 Q---TKLYKTGDLARYFPDGTIEFLGRSDRQIKIRGFRIELGEVEGTLRQHPQIQEAVVT 902
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ NP ++A++ + E + + + L L+D+MIP + ++T P+ NGK+
Sbjct: 903 SWEASPGNPRLVAYLISSEEEKPENEILNHFLAQKLSDFMIPSHFLWLDTFPLTPNGKI 961
>UniRef50_A7T272 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 705
Score = 114 bits (275), Expect = 1e-24
Identities = 63/178 (35%), Positives = 106/178 (59%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
P+G + + ++D+ M+ + G PGE+ V G LARGY+ + RFI P +
Sbjct: 334 PVGKLLPGVQIVIMDKKMKPLPVGLPGEIFVGGPTLARGYLNRPELNKERFISRPASVPA 393
Query: 201 NFA-KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ +LY TGD+G +L G + GR DS VKIRG+ +++Q V+ A+ +P ++ CVVL
Sbjct: 394 SVGERLYSTGDWGYMLSSGALEICGRCDSMVKIRGYSIEIQAVEAALLQLPMINACVVLA 453
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
G E ++ ++A+V PE +++ K+I A L + L YMIP + ++++PV +GK+
Sbjct: 454 LGEEGTDKYLVAYVV--PEGKVTKKDIRATLKTRLPFYMIPAHFVLLQSIPVAPSGKL 509
>UniRef50_A0UUS4 Cluster: Amino acid adenylation domain; n=1;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 2752
Score = 114 bits (274), Expect = 1e-24
Identities = 65/179 (36%), Positives = 103/179 (57%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++PIG PI N + ++D+NM+ G GE+C+ G LAR Y+ + +FI NP+
Sbjct: 2027 SIPIGKPIDNTKLLIMDKNMQLQPVGVTGELCIGGNCLAREYLNKPEMTDEKFIPNPYK- 2085
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
PN +LYRTGD + G I Y GR D QVKIRG R++L E++ ++ P V CVV+
Sbjct: 2086 -PN-ERLYRTGDLAKWRRDGNIEYLGRIDFQVKIRGLRIELGEIEKQLTAHPDVKECVVV 2143
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+V + I++ L SL DYM+P++ + +E +P+ NGK+
Sbjct: 2144 AWKKGEGDIHLVAYVVCENSMQAEQGGIQSFLEKSLPDYMVPRIYVFLEMMPLSPNGKI 2202
>UniRef50_O31782 Cluster: Polyketide synthase of type I; n=2; Bacillus
subtilis|Rep: Polyketide synthase of type I - Bacillus
subtilis
Length = 5488
Score = 113 bits (273), Expect = 2e-24
Identities = 66/177 (37%), Positives = 101/177 (57%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200
PIG P+SN +Y++D++++ V G+PGE+C+AG LARGY + G +FI NP +
Sbjct: 790 PIGKPVSNTKIYIVDQHLKPVPIGKPGELCIAGAGLARGYFKKPGLTAEKFIDNPFESG- 848
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
KLY++GD L G I Y GR DSQVKIRG RV+L ++ + P + + V+
Sbjct: 849 --TKLYKSGDSARWLPDGNIEYLGRIDSQVKIRGFRVELGAIETKLGEFPGILDQAVVVK 906
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+E + + A + K++ L SSL +YMIP I ++ +P+ +GKV
Sbjct: 907 QLEGHQQLAAYYTEESGHASANPKDLRLHLKSSLPEYMIPSHFIRLDELPLSPSGKV 963
>UniRef50_A5FI48 Cluster: Amino acid adenylation domain; n=2; cellular
organisms|Rep: Amino acid adenylation domain -
Flavobacterium johnsoniae UW101
Length = 2894
Score = 113 bits (273), Expect = 2e-24
Identities = 68/179 (37%), Positives = 101/179 (56%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V IG P++N VY+L EN++ G GE+C++G L++GY+ + +FI NP
Sbjct: 1557 VSIGKPVANTQVYILSENLKLQPVGVIGELCISGIGLSKGYLNQPELTKEKFIQNPFEPE 1616
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTI-PCVDNCVVL 371
KLY+TGD L G + Y GR D+QVKIRG+RV+L E+++ + + N VVL
Sbjct: 1617 ---EKLYKTGDLARWLPDGNLEYVGRKDNQVKIRGNRVELGEIEYVIREFDSAISNAVVL 1673
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
V+ + P I+A+ T + K + L L DYMIP +E+ET+ + NGKV
Sbjct: 1674 VKEVK-NEPFIIAYYTTGKS--VDKKELRKYLKDKLADYMIPAYYVELETLQLNANGKV 1729
Score = 93.1 bits (221), Expect = 4e-18
Identities = 56/181 (30%), Positives = 93/181 (51%), Gaps = 4/181 (2%)
Frame = +3
Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH 188
+ T+PIG ISN Y+LDE ++ V G G++ ++G +A GY+ + +FI NP
Sbjct: 523 YQTIPIGKAISNTQAYILDEELQLVPMGTIGKLYLSGDGIANGYLNKPELTAAKFIENP- 581
Query: 189 NTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
K+Y TGD + G + + GR D Q+K+RG+R++L+E+++ +S+ +N
Sbjct: 582 --FAEGHKMYDTGDLVKWMPDGNLAFLGRKDHQIKLRGYRIELEEIENVISSFS--ENIG 637
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGK 542
V +N E +S ++ A L L YMIP +E +P+ NGK
Sbjct: 638 QAVVAVRKNNGEDFLAAYFTEIENVSKTDLRAYLEKQLPAYMIPSYFTAVEKIPLTPNGK 697
Query: 543 V 545
+
Sbjct: 698 I 698
Score = 75.8 bits (178), Expect = 6e-13
Identities = 53/176 (30%), Positives = 88/176 (50%), Gaps = 2/176 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
+P+G + V+LLDEN + + GE+ L+ GY+ ++ + N
Sbjct: 2606 MPLGKSVEETKVFLLDENNKPKGIYQTGEIVFKSDYLSLGYLNRQELTDKVFTTDPLTGN 2665
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++Y++GD G+ L G I + R DSQVKI G R++L E+++ + I ++ VVL
Sbjct: 2666 -GRVYKSGDIGMMLPSGEIEFLQRKDSQVKINGLRIELSEIEYQLEQIEFINEAVVLLKE 2724
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ N I A+V E + I+ L L YMIP + I +E P+ GK+
Sbjct: 2725 LQ-ENSYITAYV--RSEEILDVTKIKLLLGKILPKYMIPAIYISMENFPLTRTGKI 2777
>UniRef50_A3INW8 Cluster: Peptide synthetase; n=3; Chroococcales|Rep:
Peptide synthetase - Cyanothece sp. CCY 0110
Length = 1876
Score = 113 bits (273), Expect = 2e-24
Identities = 67/178 (37%), Positives = 102/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+ IG PI+N +Y+LD +++ V G PGE+ + G LARGYV +D RFI++P N
Sbjct: 796 ITIGRPINNTQIYILDNHLQPVPIGIPGELYIGGDGLARGYVNRRDLTEERFINSPFN-- 853
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P K+Y+TGD L G + Y GR+D QVKIRG R++L E++ ++ V N VV+
Sbjct: 854 PG-KKIYKTGDIAKYLPNGKVEYIGRSDYQVKIRGFRIELGEIESQLNQHLGVKNAVVVA 912
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
S ++A+ E+ ++ +N+ L L DYM+P V I + P+ NGK+
Sbjct: 913 KKEASGINPLVAYYVSQKESNVTDENLRDFLKKKLPDYMMPLVFISLAEFPLTPNGKI 970
>UniRef50_Q4KES9 Cluster: Nonribosomal peptide synthetase; n=6;
Bacteria|Rep: Nonribosomal peptide synthetase -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 4887
Score = 113 bits (272), Expect = 3e-24
Identities = 62/176 (35%), Positives = 96/176 (54%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P++N +YLLD R V G GE+ V G +ARGY+ RF+ +P + P
Sbjct: 853 IGRPVANARIYLLDSQQRPVPIGVAGELYVGGAGVARGYLNRPQLTAERFLDDPFSDQPE 912
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YR+GD L G I Y GR D QVKIRG R++L E++ + P + V+L
Sbjct: 913 -ARMYRSGDLARWLADGRIDYLGRNDDQVKIRGVRIELGEIETRLCQFPGIQEAVLLARE 971
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ NP ++A+ T + + + A L + L DYM+P + ++ +P+ NGK+
Sbjct: 972 DQPGNPRLVAYFTQQQDVALDVAQLRAHLLAQLPDYMVPVAYVRLDALPLTANGKL 1027
Score = 106 bits (254), Expect = 4e-22
Identities = 60/176 (34%), Positives = 95/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+N +YLLD R V G GE+ V G +ARGY+ + RF+ +P +T P
Sbjct: 1897 IGRPIANARIYLLDPQQRPVPIGVAGELYVGGAGVARGYLNRPELTAERFLEDPFSTVPG 1956
Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YR+GD G I Y GR D QVK+RG R++L E++ ++ +P + V+L
Sbjct: 1957 -ARMYRSGDLARWRADGRIDYLGRNDDQVKVRGVRIELGEIETCLNRLPGIREAVLLARE 2015
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ + P A S + L L +YM+P + + +P+ NGK+
Sbjct: 2016 DQPGQTRLVAYFSATPGAEPSPAELRRRLLEQLPEYMVPAAYVHLAALPLTANGKL 2071
Score = 105 bits (252), Expect = 7e-22
Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200
PIG PI+N +YLLD M+ V G GE+ + G +ARGY+ + RF+ +P + P
Sbjct: 2955 PIGKPIANTRIYLLDAQMQPVPRGVVGELYIGGVQVARGYLNREQLSAERFLKDPFSQEP 3014
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LYRTGD L G I Y GR D QVKIRG R++L E+ ++ + V VVL
Sbjct: 3015 G-ARLYRTGDLARYLADGTIEYLGRNDDQVKIRGLRIELGEIQARLTQLEGVKEAVVLAR 3073
Query: 378 GVESSNPEILA-FVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A + T+ + ++ + + L L ++M+P + + + +P+ NGK+
Sbjct: 3074 EDVPGDQRLVAYYTTVAGQPALAVEQLRRALLEHLPEFMVPALFMHLAALPLSPNGKL 3131
Score = 87.4 bits (207), Expect = 2e-16
Identities = 56/184 (30%), Positives = 97/184 (52%), Gaps = 9/184 (4%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG P+SN VY+LD + + G GE+ + G +A GY+ D +F+ +P +
Sbjct: 4031 SVPIGRPLSNTRVYVLDALGQPLPVGVVGELYIGGDGVALGYLNRPDLSAQKFLIDPFHQ 4090
Query: 195 HPNF----AKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359
A +YRTGD G L+ G++ GR D QVKIRG R++ E+ ++ P + +
Sbjct: 4091 QTQGTAAPALMYRTGDLGRWLENGLLECIGRNDEQVKIRGLRIEPGEIQAQLARFPGLRD 4150
Query: 360 CVVLCYGVESSNPEILAFVTINPEA-RMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLV 533
V+ + ++A+ T++ A+ + + L L DYM+P + ++ +P+
Sbjct: 4151 GAVVVREDSPGDKRLVAYYTLHEHTPAPDAEQLRSHLQQQLPDYMVPLAYVHLQALPLTR 4210
Query: 534 NGKV 545
NGK+
Sbjct: 4211 NGKL 4214
>UniRef50_Q4ZT69 Cluster: Amino acid adenylation; n=8; cellular
organisms|Rep: Amino acid adenylation - Pseudomonas
syringae pv. syringae (strain B728a)
Length = 5372
Score = 113 bits (271), Expect = 3e-24
Identities = 69/184 (37%), Positives = 104/184 (56%), Gaps = 9/184 (4%)
Frame = +3
Query: 21 TVP-IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
T+P IG P++N +YLLDE+MR V G GE+ + G +ARGY+ D RFI +P
Sbjct: 1900 TLPSIGQPVANTRIYLLDEHMRPVPVGVAGELYIGGVCVARGYLNRDDLTADRFIADPFA 1959
Query: 192 THPN---FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359
T + A+LY+TGD G D G I+Y GR D Q+KIRG R++L E++ + P + +
Sbjct: 1960 TREDGNPCARLYKTGDLGCWQDDGNIIYMGRNDDQIKIRGFRIELGEIEARLGQYPGLRD 2019
Query: 360 CVVLCYGVESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLV 533
VL ++A+ ++ +A A ++ L + L DYMIP + +E +PV
Sbjct: 2020 AAVLAREDVPGEKRLVAYFSVQAGQALPEADHMRLHLQAVLPDYMIPAAYVHLEKLPVSP 2079
Query: 534 NGKV 545
NGK+
Sbjct: 2080 NGKL 2083
Score = 110 bits (265), Expect = 2e-23
Identities = 66/180 (36%), Positives = 100/180 (55%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++ IG PI+N VYLLDE+ + V G GE+ VAG +ARGY+ + RF+ +P +
Sbjct: 4024 SLDIGKPITNTRVYLLDEHQQLVPLGVAGELYVAGEGVARGYLNRPEMTAERFLRDPFHC 4083
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ A++YRTGD + G + Y GR D QVKIRG RV+L E++ +S +P ++ +VL
Sbjct: 4084 DAD-ARMYRTGDLARWNADGTLDYLGRNDDQVKIRGLRVELGEIEAQLSQLPGIEEALVL 4142
Query: 372 CYGVESSNPEILA-FVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E P + A F+ + M + A L + L YM+P + + P+ NGKV
Sbjct: 4143 AREDEPGQPRLAAYFIERDGSLSMPVSELRAALLAVLPGYMVPSAFVRLAAWPLTANGKV 4202
Score = 108 bits (259), Expect = 9e-23
Identities = 62/177 (35%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+ N YLLDE + V G GE+ + G +ARGY+ D RF+ + + HP
Sbjct: 5100 IGKPVGNTQFYLLDEQQQLVPLGVAGEIYIGGAGVARGYLNRDDLTAERFLADTFSRHPQ 5159
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD G L G I Y GR D QVKIRG R++L E+D ++ P V VV
Sbjct: 5160 -ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTARE 5218
Query: 381 VESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A+ T+ + + + ++ L L YM+P + ++ +P+ NGK+
Sbjct: 5219 DVPGDKRLVAYYTVLSAQTEPAIDSLRGWLLGQLPAYMVPVAYVRLDAMPLTPNGKL 5275
Score = 107 bits (257), Expect = 2e-22
Identities = 61/180 (33%), Positives = 103/180 (57%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194
++PIG P+ N+ +Y+LD + G GE+ + G +ARGY+ + +F+ +P ++
Sbjct: 2980 SIPIGKPVGNSRLYVLDNQGQPAPLGVGGELYIGGQGVARGYLHRDELTLEKFVADPFDS 3039
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LYRTGD G + Y GR D QVKIRG RV+L E++ ++ V VVL
Sbjct: 3040 DPQ-ARLYRTGDLVRWRADGNLEYLGRNDEQVKIRGFRVELGEIEARLAEHAEVREAVVL 3098
Query: 372 CYGVESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
C + ++A+VT PE + +++ + L L DYM+P ++++++P+ NGK+
Sbjct: 3099 CRQDAPGDKRLVAYVTAQQPETALDIEHLRSHLQGLLPDYMVPAAYVQLDSLPLTANGKL 3158
Score = 95.1 bits (226), Expect = 9e-19
Identities = 60/177 (33%), Positives = 95/177 (53%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTHP 200
PIG I + +YLLD + G GE+ V G +ARGY+ + + RF+ +P + P
Sbjct: 806 PIGKRIPDLQLYLLDAYGHPLPPGAVGELYVGGAGVARGYLNRDELNTTRFLDDPFASAP 865
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A++YR+GD G L G + Y GR D QVKIRG R++L E++ +S V + VV+
Sbjct: 866 G-ARMYRSGDLGRWLPDGSLEYLGRNDEQVKIRGFRIELGEIEARLSACEGVRDAVVVVR 924
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E + ++A+V A + +L SL ++M+P + +E P+ NGK+
Sbjct: 925 EDEPGDQRLVAYVIGTAGQEPDATWLREQLRLSLAEHMLPSAFVSLEAFPLTANGKL 981
>UniRef50_A7IZW1 Cluster: OciA; n=1; Planktothrix agardhii NIVA-CYA
116|Rep: OciA - Planktothrix agardhii NIVA-CYA 116
Length = 3477
Score = 113 bits (271), Expect = 3e-24
Identities = 61/178 (34%), Positives = 101/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V IG P+ N +Y+LD ++ V G PGE+ + G LAR Y+ + +FI NP + +
Sbjct: 2109 VSIGRPVPNTQIYILDSYLQPVPIGVPGELHIGGAGLARSYLNRPELTQEKFIPNPFSNY 2168
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+ ++LY+TGD L G I Y GR D+QVKIRG R++L E++ ++ P V + V++
Sbjct: 2169 PD-SRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIETVLTQNPQVQSSVIIA 2227
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
N ++A++ +A + + L L +YMIP + +E++P+ NGK+
Sbjct: 2228 CEDTPGNKRLVAYIVPQKDATPTPNELRQFLKEKLPEYMIPSAFVILESLPLTPNGKI 2285
Score = 109 bits (262), Expect = 4e-23
Identities = 63/176 (35%), Positives = 100/176 (56%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+ + VYLLD+ ++ V G PGE+ V G +A+GY+ + RFI +P H N
Sbjct: 3195 IGRPLPDLQVYLLDQYLQPVPVGVPGEMYVGGAGVAKGYLNRPELTTERFISSPFE-HSN 3253
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
KLY+TGD G + Y GR D+QVKIRG R++L E++ +++ P + VVL +
Sbjct: 3254 --KLYKTGDLARYWPNGELEYLGRIDNQVKIRGFRIELGEIEALLASHPQIWETVVLVWD 3311
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A++ PE + I L + L DYM+P + +E +P+ NGK+
Sbjct: 3312 DTAGDKRLVAYIVPQPEITIIIDEIRQFLKAKLPDYMVPNAFVILEALPLTTNGKI 3367
>UniRef50_A0ZF79 Cluster: Non-ribosomal peptide synthase; n=6;
Cyanobacteria|Rep: Non-ribosomal peptide synthase -
Nodularia spumigena CCY 9414
Length = 2195
Score = 113 bits (271), Expect = 3e-24
Identities = 70/183 (38%), Positives = 106/183 (57%), Gaps = 8/183 (4%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFI----HN 182
T+PIG PISN +Y+L+E ++ V G PGE+ + G LARGY+ + RFI HN
Sbjct: 353 TLPIGRPISNTQIYILNEQLQPVPVGTPGEIYIGGDGLARGYLNRPELTAERFISHPFHN 412
Query: 183 PHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359
P + N KLY+TGD L G I + GR D+QVKIRG R++L EV+ A+S P +
Sbjct: 413 PKSKIQN-PKLYKTGDLARYLPDGNIEFVGRVDNQVKIRGFRIELGEVEAALSQHPDIQQ 471
Query: 360 CVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536
VV+ + ++A+V + +A ++A ++ L L YM+P + ++ +P+ N
Sbjct: 472 AVVIVREDIPGDKRLVAYVVPDQKA-VTATTFKSFLEDKLPAYMVPTAWMLLDFLPLTPN 530
Query: 537 GKV 545
GKV
Sbjct: 531 GKV 533
Score = 92.7 bits (220), Expect = 5e-18
Identities = 63/180 (35%), Positives = 98/180 (54%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+V IG PISN VY+LD+ + V G PGE+ + G LARGY + + +FI NT
Sbjct: 1440 SVSIGKPISNAQVYILDQYQQTVPIGVPGELHIGGAGLARGYWQRPELTAEKFI---ENT 1496
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
N +LY+TGD + G + Y GR D+QVKIRG R++L E++ + P V VV+
Sbjct: 1497 EGN--RLYKTGDLVKFRRDGNLEYLGRVDNQVKIRGFRIELGEIETVLRQHPQVSQAVVI 1554
Query: 372 CYGVESSNPEILA-FVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A F+ P+ + + L L +YMIP + ++++P+ N KV
Sbjct: 1555 AHQEITGQKRLVAYFLPQGPQPTID--ELRQFLKQKLPNYMIPAAFMVLDSIPMTPNQKV 1612
>UniRef50_Q0AY10 Cluster: Non-ribosomal peptide synthetase modules and
related proteins-like protein; n=1; Syntrophomonas wolfei
subsp. wolfei str. Goettingen|Rep: Non-ribosomal peptide
synthetase modules and related proteins-like protein -
Syntrophomonas wolfei subsp. wolfei (strain Goettingen)
Length = 2638
Score = 112 bits (270), Expect = 4e-24
Identities = 58/182 (31%), Positives = 106/182 (58%), Gaps = 5/182 (2%)
Frame = +3
Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD---PHRFIHNP 185
+ VPIG P+SN +Y+LD+ R + G PGE+C++G+ ++RGY+ G+D +++ NP
Sbjct: 947 YANVPIGKPLSNTDLYILDKQGRQMPVGVPGELCISGYQVSRGYL-GRDDLTAEQYVANP 1005
Query: 186 HNTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
+N + + Y+TGD L G + + GR D QVKIRG RV+L E++ + P + +
Sbjct: 1006 YNRAEGYERYYKTGDVCRWLPDGNMEFVGRRDFQVKIRGFRVELSEIEGKIREYPGILDA 1065
Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNG 539
V+ Y + A++ + + +++ ++ + L YM+P V +++ ++P+ NG
Sbjct: 1066 TVVAYDEAGGGKYVAAYIVADHQVKIA--DLNDFIAQDLPAYMVPAVTMQLASIPLNQNG 1123
Query: 540 KV 545
KV
Sbjct: 1124 KV 1125
Score = 83.0 bits (196), Expect = 4e-15
Identities = 56/178 (31%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+ IG P+SN +Y+++EN + + G PGE+ +AG + RGYV + +FI
Sbjct: 1971 ITIGKPMSNVQIYMINENHKILPAGAPGELVIAGAGVGRGYVNKPEMTAEKFI------T 2024
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
N + YR+GD + G I + GR D QVK+RG RV+L E++ ++ + + +V+
Sbjct: 2025 INGRRAYRSGDLARWNFNGEIEFHGRIDDQVKLRGLRVELGEIEKVMNDYEGILSSIVV- 2083
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + A+ T +A + L +LT YM+P V I+++ +P+ NGKV
Sbjct: 2084 VKENQAGQFLCAYFTAQGIVDKAA--LTQHLADTLTYYMVPSVLIQLDKLPLTNNGKV 2139
>UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC
7120|Rep: All1695 protein - Anabaena sp. (strain PCC
7120)
Length = 1449
Score = 112 bits (269), Expect = 6e-24
Identities = 67/180 (37%), Positives = 103/180 (57%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++PIG PI+N VY+LD+ ++ V G GE+ + G LARGY+ D +FI +P +
Sbjct: 343 SIPIGRPIANTQVYILDDVLQLVPIGIAGELYIGGDGLARGYLNKPDLTAEKFIPHPFSD 402
Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
PN ++LY+TGD L G I + GR D QVKIRG RV+L E++ ++ P V + VVL
Sbjct: 403 KPN-SRLYKTGDRVRWLPDGTIEFLGRIDFQVKIRGFRVELGEIEAILAQHPSVRSAVVL 461
Query: 372 CYGVESSNPEILAFVTINPEAR-MSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++ ++A+ T ++ + L L +YMIP I +E +P+ NGKV
Sbjct: 462 AQEYQPADKRLVAYFTREENCNTVAPSELRHFLQQKLPNYMIPSAFISLEKLPLNANGKV 521
>UniRef50_Q333V5 Cluster: NRPS protein; n=2; Actinomycetales|Rep:
NRPS protein - Micromonospora sp. ML1
Length = 596
Score = 112 bits (269), Expect = 6e-24
Identities = 66/178 (37%), Positives = 101/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+ IG P S N VY+LDE +R V G GE+ +AG LARGY+ G RF+ +P
Sbjct: 313 ITIGTPWSGNRVYVLDERLRPVPNGRDGELYLAGNGLARGYLNRPGLTASRFVLDPFG-- 370
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YR+GD G G +++A R D QVKIRG RV+L EV+ ++ P VD V+
Sbjct: 371 PPGGRMYRSGDRGHRRADGQLVFASRGDDQVKIRGFRVELGEVEARLAAHPAVDVAAVVV 430
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
G + + + AFV+ +SA + A +L ++M+P +++ + +PV NGK+
Sbjct: 431 VG-DLAGARLAAFVSTVAGTGVSAAELSAHSAETLPEHMVPSSVQVLQRLPVTANGKI 487
>UniRef50_Q18BS4 Cluster: Putative nonribosomal peptide synthetase;
n=3; Clostridium difficile|Rep: Putative nonribosomal
peptide synthetase - Clostridium difficile (strain 630)
Length = 729
Score = 112 bits (269), Expect = 6e-24
Identities = 63/180 (35%), Positives = 101/180 (56%), Gaps = 6/180 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
+PIG PI N Y Y+LD+ + G PGE+C++G ++RGY+ +G F+ NP+ T
Sbjct: 543 IPIGKPIFNTYAYVLDKKNKLCPIGAPGELCLSGIQISRGYLNKKGLTEQVFVKNPYKTC 602
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ +YRTGD LD G + Y GR D+QVKI R++L E+++ ++ I + + V +
Sbjct: 603 EHNKLMYRTGDLVRWLDDGNLDYIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCIS 662
Query: 375 YGVESSNPEILAFVTINPE--ARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545
+ + I A+ I+ E +++ + I L L YMIP +I I+ +PV GKV
Sbjct: 663 RTNDDGDMYICAYYVIDEEDSGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKV 722
>UniRef50_Q0RI59 Cluster: Non-ribosomal peptide synthetase; n=3;
cellular organisms|Rep: Non-ribosomal peptide synthetase
- Frankia alni (strain ACN14a)
Length = 1531
Score = 112 bits (269), Expect = 6e-24
Identities = 63/178 (35%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VP+G P++N ++LDEN+R G PGE+ + G LARGY+ G RF+ +P+
Sbjct: 759 VPVGSPVANTTCHVLDENLRLAPLGVPGELYIGGAQLARGYLNRPGLSASRFVADPYG-- 816
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LYRTGD L G + + GR D QVKIRGHRV+L E++ + P V V
Sbjct: 817 PPGARLYRTGDLMRRLPSGALQFLGRVDDQVKIRGHRVELGEIESVLLAAPGVAQATVAA 876
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ A++ + A+ A + A ++L D+M+P + + +P+ +GKV
Sbjct: 877 RTDGPGGRYLAAYLVLADGAQPDAAALRAHAAATLPDHMVPATLTFLPALPLSPSGKV 934
>UniRef50_Q08MM0 Cluster: Linear gramicidin synthetase subunit B;
n=1; Stigmatella aurantiaca DW4/3-1|Rep: Linear
gramicidin synthetase subunit B - Stigmatella aurantiaca
DW4/3-1
Length = 746
Score = 112 bits (269), Expect = 6e-24
Identities = 64/178 (35%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VP+GVP+ VY+LDE M+ V EG GE+ G LARGYV + +F+ NP+
Sbjct: 435 VPLGVPLDGTDVYVLDEEMQPVPEGVVGELYTGGDGLARGYVGRPELTAEKFVPNPYGKQ 494
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD G + + GRAD+QVK+RG R+++ EV+ A+ + P V V+
Sbjct: 495 AG-QRLYRTGDLARWRGDGSLEFVGRADTQVKVRGFRIEIGEVEGALESHPEVKAAAVVV 553
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
G + ++ FV + ++ + L L +YM+P ++E+E +P+ NGKV
Sbjct: 554 QGEGAEGKRLVGFV-VGGGRKVEVGEVRGYLEKRLPEYMVPSLLVEVEKLPLTGNGKV 610
>UniRef50_A0UVH5 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain - Clostridium
cellulolyticum H10
Length = 2193
Score = 112 bits (269), Expect = 6e-24
Identities = 67/178 (37%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI N +Y+LD N + V G GE+ VAG LA+GY+ + RF+ NP++T
Sbjct: 1896 VPIGRPIDNTEIYILDSNKQLVPIGVAGELYVAGDGLAKGYLNRPELTKERFVPNPYDTS 1955
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+YR GD L G I Y GR D+QVKIRG RV+ E++ + P V VV+
Sbjct: 1956 ---GLMYRMGDMARYLPDGNIEYLGRGDNQVKIRGIRVESGEIESVLLKFPSVKEAVVVS 2012
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
YG + + A++ N + + + L++YMIP I +E +P+L NGK+
Sbjct: 2013 YGEAKGDVRLAAYIVPNVTV-PEVDELRSFIRGYLSEYMIPASINFVEHMPLLPNGKI 2069
Score = 111 bits (268), Expect = 8e-24
Identities = 68/179 (37%), Positives = 99/179 (55%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI N +Y+LD N + V G GE+ VAG LA+GY+ + RF+ NP++T
Sbjct: 836 VPIGRPIDNTEIYILDSNKQPVPIGVAGELYVAGDGLAKGYLNRPELTEERFVPNPYDTS 895
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+YR GD L G I Y GR D+QVKIRG RV+L E++ + P V VV+
Sbjct: 896 ---GLMYRMGDMARYLPDGNIEYLGRGDNQVKIRGIRVELGEIESVLLKFPSVKEAVVVS 952
Query: 375 YGVESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
YG + + A++ P+ + + + + L +YMIP I +E +P+L NGK+
Sbjct: 953 YGELKGDVRLAAYIV--PDVTVPEVDELRSFIRGYLPEYMIPVSINFVEHIPLLPNGKI 1009
>UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep:
Peptide synthetase 2 - Bacillus subtilis
Length = 2560
Score = 112 bits (269), Expect = 6e-24
Identities = 61/176 (34%), Positives = 98/176 (55%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+S +++D +M G PGE+ + G +ARGY+ + RF+ NP+
Sbjct: 1815 IGRPLSTLQAHVMDAHMNLQPTGVPGELYIGGEGVARGYLNRDELTADRFVSNPYLPGD- 1873
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LYRTGD L G + Y GR D QVK+RGHR++L E+ A+ P + V+
Sbjct: 1874 --RLYRTGDLAKRLSNGELEYLGRIDEQVKVRGHRIELGEIQAALLQYPMIKEAAVITRA 1931
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E I A++ I + + +I L ++L D+M+P ++I+I+++PV VNGK+
Sbjct: 1932 DEQGQTAIYAYMVIKDQQAANISDIRTYLKNALPDFMLPARMIQIDSIPVTVNGKL 1987
Score = 104 bits (250), Expect = 1e-21
Identities = 64/178 (35%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
+ IG PI N V++L N + G GE+C++G LARGY + ++ + HP
Sbjct: 776 ITIGHPIRNTKVFVLHGN-QMQPIGAAGELCISGAGLARGYYKQQE---LTQKAFSDHPF 831
Query: 204 FA--KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD G L G I Y GR D QVKIRG+R++L+E++ + P V VL
Sbjct: 832 LEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIRGYRIELREIETVLRQAPGVKEAAVLA 891
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
V + E++A++ PE S ++ L +L YMIP +I I +P+ +GK+
Sbjct: 892 RDVSAEEKELVAYIV--PEKGNSLPDLYQHLAGTLPSYMIPASIINISQMPLTSSGKL 947
>UniRef50_Q3M5M7 Cluster: Amino acid adenylation; n=1; Anabaena
variabilis ATCC 29413|Rep: Amino acid adenylation -
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length = 1786
Score = 111 bits (268), Expect = 8e-24
Identities = 58/176 (32%), Positives = 102/176 (57%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+N +Y+LD++++ V G GE+ + G LA+GY+ + +FI +P + P
Sbjct: 1485 IGRPIANTQIYILDQHLQPVPIGVTGELHIGGNGLAQGYLHRPELTAEKFIAHPFSNQPT 1544
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LY+TGD G I + GR D QVKIRG R++L E++ A++ P V CVV+
Sbjct: 1545 -ARLYKTGDLARYRSDGTIEFIGRIDHQVKIRGFRIELGEIETALNQHPQVRECVVIASD 1603
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++ ++ A++ + + ++ + + L L +YMIP ++E +P+ N K+
Sbjct: 1604 DQLAHQQLQAYIVFHQQLKVDSSELHRFLKQKLPEYMIPTSFFQLENIPLTPNAKI 1659
>UniRef50_O07944 Cluster: Pristinamycin I synthase 3 and 4; n=2;
Streptomyces|Rep: Pristinamycin I synthase 3 and 4 -
Streptomyces pristinaespiralis
Length = 4848
Score = 111 bits (268), Expect = 8e-24
Identities = 67/182 (36%), Positives = 101/182 (55%), Gaps = 8/182 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNTH 197
VPIG P+ N Y+LDE +R V G GE+ +AG LARGY + RF +PH H
Sbjct: 4307 VPIGRPLDNTRAYVLDERLRPVPPGVTGELYIAGAGLARGYWDQSARTAERFTADPH-AH 4365
Query: 198 ---PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
++YRTGD D GV+ + GRAD QVKIRG R++ E++ A++ P V
Sbjct: 4366 LFGDTGGRMYRTGDLARRDADGVLHFCGRADQQVKIRGFRIEPGEIETALAAHPDVTRAA 4425
Query: 366 VLCYGVESSNPEILAFVTINPEA-RMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNG 539
V+ + + ++A++ P+A +A+ + A L + L DYM+P + + +PV NG
Sbjct: 4426 VVARPGRAGDKVLVAYLVTAPDAGDTTAEQLRAGLETQLPDYMVPAAFVALPALPVTPNG 4485
Query: 540 KV 545
K+
Sbjct: 4486 KL 4487
Score = 109 bits (263), Expect = 3e-23
Identities = 64/179 (35%), Positives = 104/179 (58%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNT 194
+ PIG P+ ++ VY+LD +R V G GE+ +AG +ARGY+ RF+ +P+
Sbjct: 3252 SAPIGRPVDHDRVYVLDSALRPVPPGVTGELYLAGAGVARGYLHRPRTTAERFVADPYAP 3311
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A++YRTGD G + +G + +AGRAD QVKIRG RV+ EV+ A++ P + VL
Sbjct: 3312 RPG-ARMYRTGDLGRWNTRGELEFAGRADHQVKIRGFRVEPGEVEAALTAHPRITQAAVL 3370
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+G ++A+V + ++ + L + L D+M+P + +E +P+ VNGK+
Sbjct: 3371 AHG-----DRLVAYVVTTADRDLT--GVREHLAARLPDFMVPTAYVRLEALPLTVNGKL 3422
Score = 107 bits (256), Expect = 2e-22
Identities = 59/177 (33%), Positives = 102/177 (57%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200
P+G P+S VY+LD +R V G GE+ +AG ++RGY+ RF+ +P+ P
Sbjct: 772 PLGRPVSGARVYVLDSALRPVAPGVTGELYLAGAGVSRGYLNRPVLTAERFVADPYAPSP 831
Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A++YRTGD G + +G + +AGRAD QVKIRG R++ E++ A++ +P V V+
Sbjct: 832 G-ARMYRTGDLGRWNTRGELEFAGRADHQVKIRGFRIEPGEIEAALTDLPAVARAAVVVR 890
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A+ E + A + + L +L D+M+P ++ ++ +P+ NGK+
Sbjct: 891 EDRPGDKRLVAYAVPAGEG-LDAAAVRSRLARTLPDFMVPAAIVALDALPLTPNGKL 946
Score = 84.6 bits (200), Expect = 1e-15
Identities = 49/136 (36%), Positives = 78/136 (57%), Gaps = 5/136 (3%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT-- 194
PIG P+++ VY+LDE +R V G GE+ V+G +ARGY+ RF+ +P+
Sbjct: 1811 PIGRPVAHARVYVLDERLRPVPPGVTGEMYVSGAGVARGYLHRPALTAQRFVPDPYALLF 1870
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
++YRTGD LD G + +AGRAD QVKIRG R++ E++ ++ P V V+
Sbjct: 1871 GETGTRMYRTGDLARLDADGRLHFAGRADQQVKIRGFRIEPGEIETVLTAHPAVAAGAVI 1930
Query: 372 CYGVESSNPEILAFVT 419
+ +++A++T
Sbjct: 1931 AREDTPGDKQLVAYLT 1946
>UniRef50_A6ASZ6 Cluster: Enterobactin synthetase component F; n=2;
Vibrio harveyi|Rep: Enterobactin synthetase component F -
Vibrio harveyi HY01
Length = 1315
Score = 111 bits (268), Expect = 8e-24
Identities = 62/180 (34%), Positives = 101/180 (56%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++PIG P+ N +Y+LD+ + V G G + +AG LA+GY + RFI NP
Sbjct: 777 SIPIGRPVWNTQIYILDDALNPVPPGVVGHLYIAGRQLAQGYYGQPELTAERFIDNPFG- 835
Query: 195 HPNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +++Y +GD + G I Y GR+D QVKIRG R++L+E+++A++ P V VL
Sbjct: 836 -PQGSRMYLSGDLARWREDGAIEYCGRSDFQVKIRGFRIELEEIENALANHPSVAQVAVL 894
Query: 372 CYGVESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+VT N E + + ++ L L +YM+P +E+E P+ NGK+
Sbjct: 895 AQEYNDGDKRLVAYVTAENTEQGIDSNALQTYLAEPLPEYMVPSYFVELEAFPLTPNGKL 954
>UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1;
Brevibacillus texasporus|Rep: Nonribosomal peptide
synthetase F - Brevibacillus texasporus
Length = 2491
Score = 111 bits (267), Expect = 1e-23
Identities = 67/178 (37%), Positives = 100/178 (56%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI+N+ VY+LD+N G PGE+CV+G LARGY+ + RF+ NP P
Sbjct: 768 PIGKPITNHSVYILDQNRHLQPIGIPGELCVSGAGLARGYLNQPELTVERFVDNPF--VP 825
Query: 201 NFAKLYRTGDF--GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD +D G I Y GR D QVKIRG+R++L E++ + P + +V+
Sbjct: 826 G-ERMYRTGDLVRWRID-GSIEYLGRIDEQVKIRGYRIELGEIETKLLEHPSISEALVVA 883
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E + A+V S ++ L +L +YMIP ++E+E +P+ NGK+
Sbjct: 884 RNDEQGYTYLCAYVVAT--GAWSVSSLREHLIETLPEYMIPAYMMEVEKMPLTANGKI 939
Score = 101 bits (241), Expect = 1e-20
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG P+ N V++L + + G GE+CV+G LARGY+ + RF+ NP
Sbjct: 1802 IPIGRPLHNTTVHILSADDKLQPIGVIGELCVSGEGLARGYLNLPELTMERFVENPFR-- 1859
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD L GV+ Y GR D QVKIRGHR++L E++ + P + V+L
Sbjct: 1860 PG-ERMYRTGDLARWLPDGVLEYVGRKDEQVKIRGHRIELSEIETRILEHPAISETVLLA 1918
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E + + A++ + + + + + + L ++M+P I ++ +P+ NGKV
Sbjct: 1919 KRNEQGSSYLCAYIVAH--GQWNIQELRKHVRDVLPEHMVPSYFIGLDKLPLTSNGKV 1974
>UniRef50_A3KFG5 Cluster: PstC protein; n=2; Actinomycetales|Rep: PstC
protein - Actinoplanes friuliensis
Length = 6661
Score = 111 bits (267), Expect = 1e-23
Identities = 65/176 (36%), Positives = 98/176 (55%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG PI+N VY+LD +R V G PGEV +AG + RGY + RF+ NP+ T
Sbjct: 2813 IGTPIANTQVYVLDAALRPVPAGVPGEVYIAGDGVVRGYWQRPALTAQRFVANPYGT--T 2870
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++ YRTGD G G + Y RAD QVK+RG+R++L E++ ++ P V VL
Sbjct: 2871 GSRFYRTGDIGRWAADGTLEYLSRADDQVKLRGYRIELGEIEAVLAADPAVVQAAVLVRE 2930
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A+V R SA + + SL +YM+P ++E++T P+ NGK+
Sbjct: 2931 DRPGDKRLVAYV------RGSADGLRERIARSLPEYMVPAAIVELDTFPLTPNGKL 2980
Score = 109 bits (262), Expect = 4e-23
Identities = 67/178 (37%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P N Y+LDE +R V G GE+ VAG LARGY + G RF+ NP
Sbjct: 1782 VPIGRPFWNTQAYVLDERLRPVPPGVTGELYVAGVVLARGYWQRPGLTAERFVANPFGAA 1841
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD + G ++YAGRAD+QVK+RG R++L E++ ++T P V VL
Sbjct: 1842 GT--RLYRTGDRARWNADGNLVYAGRADAQVKVRGFRIELGEIEAVLTTDPAVTQAAVLV 1899
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+V R S + + +L DYM+P + ++ P+ NGK+
Sbjct: 1900 REDQPGDKRLVAYV------RGSVDGLRERVAQALPDYMVPAAFVALDEFPLTPNGKL 1951
Score = 104 bits (250), Expect = 1e-21
Identities = 63/176 (35%), Positives = 96/176 (54%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG PI+N VY+LD +R V G GEV +AG + RGY + G RF+ NP+ T
Sbjct: 4855 IGSPIANTQVYVLDAALRPVPAGVAGEVYIAGDGVVRGYWQRPGLTAQRFVANPYGT--T 4912
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++ YRTGD G G++ Y RAD QVK+RGHR++L E++ ++ V V+
Sbjct: 4913 GSRFYRTGDIGRWAADGMLEYLSRADDQVKLRGHRIELGEIEAVLAADAAVAQAAVIVRE 4972
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V R SA + ++L YM+P +E++T P+ NGK+
Sbjct: 4973 DRPGDKRLVAYV------RGSADGLRDRAAAALPGYMVPAAFVELDTFPLTPNGKL 5022
Score = 103 bits (247), Expect = 3e-21
Identities = 64/178 (35%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P N Y+LD ++ V G GE+ VAG LARGY + G RF+ NP
Sbjct: 3826 VPIGRPFWNTQAYVLDAALQPVSAGVTGELYVAGVVLARGYWQRPGLTAERFVANPFGA- 3884
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +LYRTGD + G ++Y GRAD QVK+RG R++L E++ ++T P V V+
Sbjct: 3885 PG-TRLYRTGDLVRWNADGTLVYLGRADGQVKLRGFRIELGEIEAVLTTDPAVTQAAVVV 3943
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+V R S + + +L DYM+P + ++ P+ NGK+
Sbjct: 3944 REDQPGDKRLVAYV------RGSVDGLRERVAQALPDYMVPSAFVALDEFPLTPNGKL 3995
Score = 102 bits (245), Expect = 5e-21
Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VP+G P N VY+LD +R V G PGE +AG LARGY R G RF+ NP +
Sbjct: 764 VPVGRPFWNTRVYVLDAGLRPVPAGVPGEAYIAGTGLARGYWRRPGLSAERFVANPFD-G 822
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YRTGD + G + + GR D QVK+RG+R++L E++ ++ V VL
Sbjct: 823 PG-ARMYRTGDVVRWNTDGQLEFVGRGDGQVKLRGYRIELGEIESVIAADDAVTQAAVLV 881
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V R +A + + L DYM+P + ++ P+ NGK+
Sbjct: 882 REDRPGDKRLVAYV------RGNADGLRERVAELLPDYMVPAAFVVLDVFPLTPNGKL 933
Score = 100 bits (240), Expect = 2e-20
Identities = 58/178 (32%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P+ N VY+LDE ++ V G GE+ +AG +ARGY+ G RF+ +P
Sbjct: 5898 VPIGAPLWNTRVYVLDERLQPVAPGVKGELYLAGAGVARGYLGRPGLTGQRFVADPFTGS 5957
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD D G +++AGR D QVK+RG RV+ E++ + P V V+
Sbjct: 5958 GE--RMYRTGDVVSWDADGRLIFAGRVDDQVKLRGFRVEPGEIEAVLRQRPEVAEAAVIL 6015
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+V ++ + ++L DY++P V+ ++ +P+ NGK+
Sbjct: 6016 REDRPGDKRLVAYVVTAAAFSAHPDDLRRHVAATLPDYLVPSAVVLVDVLPLTANGKL 6073
>UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1;
Alcanivorax borkumensis SK2|Rep: Peptide synthetase,
putative - Alcanivorax borkumensis (strain SK2 / ATCC
700651 / DSM 11573)
Length = 3600
Score = 111 bits (266), Expect = 1e-23
Identities = 66/179 (36%), Positives = 108/179 (60%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVPIG PISN +Y+LD ++ V G PGE+ +AG LARGY D RF+ NP+
Sbjct: 3312 TVPIGAPISNIQLYVLDTDLNPVPRGVPGELYLAGIGLARGYFGRSDLTAERFVPNPYGD 3371
Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+++YRTGD G+I Y GR D QVKIRG R++L E++ + +P V++ VV+
Sbjct: 3372 AG--SRMYRTGDQVRQRGDGIIEYLGRLDHQVKIRGLRIELGEIEQQLKQLPDVNDAVVV 3429
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ + +++A+V+ + + R + + L +L +YM+P + + +E +P+ NGK+
Sbjct: 3430 ADHSDTGD-QLVAYVSADSDNR---EVWQQALADALPEYMVPALFMVLEALPLSPNGKL 3484
Score = 89.0 bits (211), Expect = 6e-17
Identities = 61/178 (34%), Positives = 92/178 (51%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAG-FNLARGYVRGKD--PHRFIHNPHNTH 197
PIG + +Y+LD+++ V G GE+ + LARGY + D RF+ +P
Sbjct: 2267 PIGHAVGPRKLYVLDQDLNRVPVGVAGELYIGNEVGLARGYHQRPDLTAERFLPDPFG-E 2325
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD D GV+ Y GR D QVKIRG R++L E++ + P V VVL
Sbjct: 2326 PG-ERMYRTGDLVKYRDDGVMEYLGRVDQQVKIRGFRIELGEIESRLLAHPQVREAVVLA 2384
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ ++ P +S + A L SL DYM+P ++ +E +P+ GKV
Sbjct: 2385 Q-PSPGGDRLVGYLV--PRGPLSTDALIATLAESLPDYMVPSHLLTLEAMPLTPAGKV 2439
Score = 81.8 bits (193), Expect = 9e-15
Identities = 59/183 (32%), Positives = 93/183 (50%), Gaps = 10/183 (5%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAG-FNLARGYVRGKD--PHRFIHNPHNTH 197
PIG + +Y+LD+++ V G GE+ + LARGY + D RF+ +P
Sbjct: 786 PIGHAVGPRKLYVLDQDLNRVPVGVAGELYIGNEVGLARGYHQRPDLTAERFLPDPFG-E 844
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD D GV+ Y GR D QVKIRG R++L E++ + + V+
Sbjct: 845 PG-ERMYRTGDLVKYRDDGVMEYLGRVDQQVKIRGFRIELGEIESQLLGHEQIREAAVVA 903
Query: 375 YGVESSNPEILAFVTINPEARM-----SAKNIEAELTSSLTDYMIP-QVIEIETVPVLVN 536
+ ++ ++ + A + I A L+ SL DYM+P Q+I +E +P+
Sbjct: 904 Q-PSPTGDRLVGYIVMRNAAHSVPREHDPQTILAALSESLPDYMVPSQLITLEAMPLTPA 962
Query: 537 GKV 545
GKV
Sbjct: 963 GKV 965
>UniRef50_UPI000038DECD Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal
peptide synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 1141
Score = 110 bits (265), Expect = 2e-23
Identities = 60/180 (33%), Positives = 101/180 (56%), Gaps = 7/180 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V IG P+ + VY+LDE+++ V GE GE+C+ G + +GYV + +F+ NP
Sbjct: 338 VTIGKPLPDYSVYILDEHLQEVPLGEIGEICIGGIGVTQGYVNLPEQTASKFVTNPFEQS 397
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
K+YR+GD G + G I + GR D QVKIRG+R++L E++ + ++N +V
Sbjct: 398 HKGEKIYRSGDLGRVTPDGEIEFLGRIDHQVKIRGYRLELTEIEAILLENQEIENAIVSL 457
Query: 375 YGVESSNPEILAFVTIN---PEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGK 542
+ + E+ A++T++ + ++ L+S L YM+P I+I + +P L NGK
Sbjct: 458 VSINDAVKELAAYITLHIPVTDPEALKYSLYTSLSSRLPSYMVPAFIDILDAIPTLPNGK 517
>UniRef50_Q93N87 Cluster: Peptide synthetase; n=12; Bacteria|Rep:
Peptide synthetase - Streptomyces lavendulae
Length = 4898
Score = 110 bits (265), Expect = 2e-23
Identities = 64/178 (35%), Positives = 103/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+P+G P++N VY+LD ++ V G GE+ +AG LARGY++ G RF+ P
Sbjct: 2260 LPVGSPLANRQVYVLDAFLQPVPPGVAGELYIAGAGLARGYLKRAGLSAERFVACPF--- 2316
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ ++YRTGD D G + +AGRAD+QVKIRG RV+L EV+ A++ P V VV+
Sbjct: 2317 ADGERMYRTGDLARWTDDGELAFAGRADAQVKIRGFRVELGEVEAALAAQPAVAQAVVVA 2376
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ ++ + + + + A L +L DYM+P ++ ++ +P+ VNGKV
Sbjct: 2377 REGRPGEKRLVGYL-VPHGGQPDSDVLRARLAQTLPDYMVPAALVVLDALPLTVNGKV 2433
Score = 98.3 bits (234), Expect = 1e-19
Identities = 60/178 (33%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+P+G P+ N VY+LD + V G GE+ +AG LARGY++ G RF+ P
Sbjct: 765 LPVGRPLGNRQVYVLDAYLHPVAPGVTGELYIAGAGLARGYLKRAGLSSERFVACP---F 821
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ ++YRTGD G +++ GRAD+QVK+RG RV+L EV+ A++ V + VV
Sbjct: 822 ADGERMYRTGDLVRWTSDGELVFVGRADAQVKVRGFRVELGEVEAALAAEAGVGHAVVTA 881
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ +V + E + + + L L +YM+P +I ++ +P+ NGKV
Sbjct: 882 REDRPGERRLIGYVLPDGE-DVDTELLREHLAKVLPEYMVPAALIVLDALPLTANGKV 938
Score = 86.2 bits (204), Expect = 4e-16
Identities = 50/119 (42%), Positives = 72/119 (60%), Gaps = 3/119 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
VP+G PI+N Y+LD +R V G GE+ VAG LARGY+ G RF+ +P
Sbjct: 3783 VPVGRPIANGRTYVLDPFLRPVPPGVTGELYVAGAGLARGYLGQGGLTATRFVPDPFT-- 3840
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD G++++AGRAD+QVK+RGHR++ EV+ ++ P V V+
Sbjct: 3841 PG-ERMYRTGDLARWTHDGLLVFAGRADAQVKVRGHRIEPGEVEAVLAEHPGVAQAAVV 3898
>UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide synthetase/polyketide
synthase; n=27; root|Rep: Non-ribosomal peptide
synthetase/polyketide synthase - Myxococcus xanthus
(strain DK 1622)
Length = 14274
Score = 110 bits (265), Expect = 2e-23
Identities = 65/179 (36%), Positives = 97/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG P+SN Y+LD ++ V G PGE+ V G L RGYV D RFI P T
Sbjct: 6127 SVPIGRPVSNTQAYVLDSQLQLVPVGVPGELYVGGEGLGRGYVSRPDLTAERFIPAPFAT 6186
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LYRTGD G + + GR D+QVK+RG R++L +V+ A+ T P V +
Sbjct: 6187 QPG-ARLYRTGDLVRWRPDGTLEFIGRIDNQVKVRGFRIELADVEAALRTQPGVLEAAAV 6245
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ +A + + A + L +YM+P V + + T+P+ +GKV
Sbjct: 6246 VREDIPGDKRLVAYAMGRDDAPLDVAALRAGMRQRLPEYMVPSVFVVLPTLPLSTSGKV 6304
Score = 106 bits (255), Expect = 3e-22
Identities = 67/179 (37%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNT 194
+V IG PI+N VY+LD MR G PGEV + G LARGY+ RF+ NP
Sbjct: 4001 SVSIGRPIANTQVYVLDPAMRAAPVGVPGEVFIGGDGLARGYLGQPALTAERFVPNPFG- 4059
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LYR+GD L G + + GR D QVK+RG R++L E++ A+ + V+ + L
Sbjct: 4060 -PPGARLYRSGDRARWLADGTLQFLGRVDFQVKLRGFRIELGEIETALRSHSEVETAIAL 4118
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+VT PE + ++ L L +YM+P V+ + T+P+ NGKV
Sbjct: 4119 VREDSPGDRRLVAYVT--PE-DVDTASLREHLRQRLPEYMVPNAVVVLSTLPLSPNGKV 4174
Score = 102 bits (244), Expect = 6e-21
Identities = 66/180 (36%), Positives = 98/180 (54%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
L+VPIG PI N VY+LD + V G PGE+C+ G LARGY+ D F+ +P +
Sbjct: 2941 LSVPIGRPIDNTEVYVLDPALCPVPVGVPGELCLGGPGLARGYLNRPDLTAECFVPHPFS 3000
Query: 192 THPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
P A+LYRTGD GV+ + GR D QVK+RG R++L E++ + P V V
Sbjct: 3001 AVPG-ARLYRTGDRVRWRPDGVLEFLGRLDHQVKVRGFRIELGEIEAVLRAHPFVAEATV 3059
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ S + ++A+V + P+ ++ + L L DYM+P I ++ P+ GKV
Sbjct: 3060 VVREDGSGSNRLVAYV-VPPQPDVAP--LREYLHQHLPDYMLPSAFIGLDAFPLTPTGKV 3116
Score = 101 bits (243), Expect = 8e-21
Identities = 62/181 (34%), Positives = 99/181 (54%), Gaps = 4/181 (2%)
Frame = +3
Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH 188
F VPIG P++N +Y+LD + + G PGE+ + G + RGY + RFI +
Sbjct: 9474 FHRVPIGRPVANTVLYVLDTHGQPAPVGIPGELHIGGVQVGRGYWQRPQLTAERFIPDAF 9533
Query: 189 NTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
+ P A+LYRTGD L G + Y GRAD QVK+RG R++L E++ A+ P V + V
Sbjct: 9534 SGIPG-ARLYRTGDVARWLPDGTLEYLGRADFQVKLRGFRIELGEIETALRMHPGVRDAV 9592
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542
+ + ++A+VT A + A+ + A+L L +M+P + + +P+ +GK
Sbjct: 9593 AVVREETRGDARLVAYVT-GDSAPLEAETLRAQLLKQLPQHMVPSTFVHLGVLPLTPSGK 9651
Query: 543 V 545
V
Sbjct: 9652 V 9652
Score = 98.3 bits (234), Expect = 1e-19
Identities = 65/181 (35%), Positives = 99/181 (54%), Gaps = 4/181 (2%)
Frame = +3
Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH 188
F VPIG P++N +Y+LD + + G PGE+ + G + RGY + RFI +
Sbjct: 5059 FHRVPIGRPVANTVLYVLDVHGQPAPVGIPGELHIGGVQVGRGYWQRPQLTAERFIPDAF 5118
Query: 189 NTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
+ P A+LYRTGD L G + Y GRAD QVK+RG R++L EV+ A+ V + V
Sbjct: 5119 SGIPG-ARLYRTGDVARWLADGTLEYLGRADFQVKLRGFRIELGEVEAALRAHLDVFDAV 5177
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGK 542
+ + ++A+VT P ++A + A L L +M+P IE + ++P+ NGK
Sbjct: 5178 AVVREDAPGDQRLVAYVTGEPALDVAA--LRARLVEQLPAHMVPTAIETLPSLPLSPNGK 5235
Query: 543 V 545
V
Sbjct: 5236 V 5236
Score = 95.9 bits (228), Expect = 5e-19
Identities = 62/176 (35%), Positives = 94/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG PI VY+LD + G GE+C+AG +ARGY G RFI + + P
Sbjct: 12673 IGRPIVGTRVYVLDSRQQLAPLGTAGELCIAGEGVARGYFGRPGLTAERFIPDAFSGQPG 12732
Query: 204 FAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LYRTGD G + Y GR D QVK+RG R++L E++ A+ T V + VVL
Sbjct: 12733 -ARLYRTGDKARWRHDGTLEYLGRLDFQVKVRGFRIELGEIEAALRTHGQVQDAVVLARE 12791
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V + ++A+++ L L +YM+P V + + +P+ GKV
Sbjct: 12792 DVPGDKRLVAYVVGD---FITAESLRQHLLQRLPEYMVPSVFVPLAALPLTSTGKV 12844
Score = 91.9 bits (218), Expect = 9e-18
Identities = 55/152 (36%), Positives = 88/152 (57%), Gaps = 3/152 (1%)
Frame = +3
Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH 188
F VPIG P++N +Y+LD + + G PGE+ + G + RGY + RFI +
Sbjct: 1468 FHRVPIGRPVANTVLYVLDVHGQPAPVGIPGELHIGGVQVGRGYWQRPQLTAERFIPDAF 1527
Query: 189 NTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
+ P A+LYRTGD L G + Y GRAD QVK+RG R++L E++ A++ P V + V
Sbjct: 1528 SGIPG-ARLYRTGDVARWLPDGTLEYLGRADFQVKLRGFRIELGEIEAALAADPAVHDSV 1586
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEA 461
VL + + ++A+V ++ A +A+ ++A
Sbjct: 1587 VLAREDSTGDQRLVAYVVLDDAA--AAQEVDA 1616
Score = 91.5 bits (217), Expect = 1e-17
Identities = 58/181 (32%), Positives = 100/181 (55%), Gaps = 7/181 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG ++N +Y+LD + V G PGE+ + G+ +ARGY+ + RF+ +P
Sbjct: 11609 VPIGRALTNVRMYVLDRELEPVPPGVPGELFIGGWGVARGYLGRPELTAERFVPSP---F 11665
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ +LYRTGD + G + Y GR D+QVK+RG R++ E++ A+ P V + VV
Sbjct: 11666 VDSERLYRTGDLARWRRDGNLEYLGRGDTQVKVRGVRIEPGEIEAALRAHPTVHDAVVHV 11725
Query: 375 YGVESSNPEILAFVTIN--PEA-RMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGK 542
+ + ++A+V + P A ++ A + L +L +YM+P + + +P+ +GK
Sbjct: 11726 REDVAGDKRLVAYVVPSSAPSAGQLEASALREHLRGNLPEYMVPGAFVSLAALPLTPSGK 11785
Query: 543 V 545
V
Sbjct: 11786 V 11786
Score = 90.6 bits (215), Expect = 2e-17
Identities = 62/179 (34%), Positives = 93/179 (51%), Gaps = 7/179 (3%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHNTHP 200
IG PI Y+LD R G GE+ ++G LARGY +G+ RFI + + P
Sbjct: 10538 IGRPIQGTRAYVLDARQRVAPAGIAGELYLSGDGLARGY-QGQPQLTAERFIPDAFSGTP 10596
Query: 201 NFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LYRTGD G + Y GR D QVK+RG R++L E++ + T V VVL
Sbjct: 10597 G-ARLYRTGDKARWRHDGTLEYLGRLDFQVKLRGFRIELGEIEAVLRTHDQVQEAVVLVR 10655
Query: 378 GVESSNPEILAF--VTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ V + PEA ++A+ + L +YM+P + + T+P+ GKV
Sbjct: 10656 EDVPGDKRLVAYVVVVVTPEAPVTAELLRQHAQERLPEYMVPSAFVLMGTLPLTPTGKV 10714
Score = 85.8 bits (203), Expect = 6e-16
Identities = 56/176 (31%), Positives = 91/176 (51%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG P++ ++LD + G GE+ +AG LARGY+ G RF+ +P + P
Sbjct: 13732 IGKPLAGTRAFVLDARQQLAPLGTAGELYLAGDGLARGYLGQPGLTAERFVPHPFASTPG 13791
Query: 204 FAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LYRTGD G + Y GR D QVK+RG R++L E++ A+ V + VVL
Sbjct: 13792 -ERLYRTGDKARWRHDGTLEYLGRLDFQVKLRGFRIELGEIEAALRAHEAVQDAVVLARE 13850
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A++ + A + A + L L +YM+P + + +P+ +GKV
Sbjct: 13851 DVPGDKRLVAYI-VGGSATVEA--LRQHLQQRLPEYMVPPAFVSLPALPLNPSGKV 13903
Score = 40.3 bits (90), Expect = 0.028
Identities = 34/132 (25%), Positives = 59/132 (44%), Gaps = 4/132 (3%)
Frame = +3
Query: 33 GVPISNNYVYLLDENMRC-VREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFA 209
G ++ + ++D R G+ GE+ V+G ++A+GY R + I
Sbjct: 376 GSTLAEQRLLIVDPESRVPCAPGQVGEIWVSGGSVAQGYWRKPEDSVDIFQAVPVGAEAG 435
Query: 210 KLY-RTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTI-PCVDNCVVLCYG 380
Y RTGD G +L+ G ++ GR + +RG + Q+V+ V V + +
Sbjct: 436 PKYLRTGDLGLLLEDGQLIVTGRRKDLIILRGRNLYPQDVESIVERAHRKVRPGCIAAFA 495
Query: 381 VESSNPEILAFV 416
+E+ E LA V
Sbjct: 496 IETPEGEALAVV 507
>UniRef50_A4PHL4 Cluster: Non ribosomal peptide synthetase for
virginiamycin S; n=3; Actinomycetales|Rep: Non ribosomal
peptide synthetase for virginiamycin S - Streptomyces
virginiae
Length = 2671
Score = 110 bits (265), Expect = 2e-23
Identities = 64/179 (35%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194
TVPIG P+ N ++LD+ +R V G GE+ + G LARGY+ D RF+ +P T
Sbjct: 1892 TVPIGSPLDNTTCHVLDQRLRPVPPGVTGELYIGGARLARGYLGRPDATAERFVADPSGT 1951
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A++YRTGD G++ + GRAD QVK+RG R++L E++ + P V VL
Sbjct: 1952 -PG-ARMYRTGDLVRRRADGILEFLGRADHQVKVRGFRIELGEIESVIGRHPTVAQSAVL 2009
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + A+V A A + + +SL DYM+P V+ ++ +P+ NGK+
Sbjct: 2010 VREDRPGDKRVTAYVVPAAAAAADAGELRRHVAASLPDYMVPAAVVLLDRLPLTPNGKL 2068
Score = 81.8 bits (193), Expect = 9e-15
Identities = 54/177 (30%), Positives = 88/177 (49%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
+G P+++ ++LD +R G GE+ VAG LARGY+ RF+ +P +
Sbjct: 831 VGAPLADLRAHVLDGALRPAPPGVTGELYVAGPGLARGYLGLPALTAERFVADPFAPAGD 890
Query: 204 F-AKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A++YRTGD G + Y GRAD QVKIRG R++L E++ A++ +P V + V
Sbjct: 891 TGARMYRTGDLVRRRADGTLEYVGRADHQVKIRGFRIELGEIEAALAALPSVAHAAVTAR 950
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + A+ EL + L + +P ++ +P+ VNGK+
Sbjct: 951 EDTPGDRRLAAYAVPADGVPADPAAWRRELAAVLPAHQLPASFTPLDAIPLTVNGKL 1007
>UniRef50_Q8PKR8 Cluster: ATP-dependent serine activating enzyme; n=1;
Xanthomonas axonopodis pv. citri|Rep: ATP-dependent
serine activating enzyme - Xanthomonas axonopodis pv.
citri
Length = 1566
Score = 110 bits (264), Expect = 2e-23
Identities = 61/179 (34%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+PIG PI N VYLLD N + V G GE+C+AG + RGY+ + RF+ +P T
Sbjct: 795 TIPIGRPIDNMRVYLLDANRQTVPAGVAGELCIAGSQVTRGYLNRPELTEQRFVVDPFGT 854
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++Y +GD + G + Y GR D Q+K+RG R++ EV + P V + V+
Sbjct: 855 GPE-QRMYCSGDLARWMPDGTLEYLGRNDDQIKLRGFRIEPAEVSSRILDNPLVADAAVV 913
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ S ++A+ ++ ++A+ + +L L DYM+P V I ++ +P+ NGK+
Sbjct: 914 IHTAASGEKCLVAYY-VSDAPEVTAERLREQLQQRLPDYMVPAVYIRMDLLPMTPNGKL 971
>UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3;
Bacteria|Rep: Non-ribosomal peptide synthetase - Erwinia
carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 7523
Score = 110 bits (264), Expect = 2e-23
Identities = 61/179 (34%), Positives = 100/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T PIG PI+N +Y+LDE + V G GE+ + G +ARGY+ + RFI +P
Sbjct: 4007 TPPIGRPIANTQIYILDEQKQPVPLGVAGEIYIGGAGVARGYLNRPELTAERFIADPFTD 4066
Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P+ A+LY+TGD G L G I Y GR D Q+K+RG R++L E++ + V VV+
Sbjct: 4067 TPD-ARLYKTGDLGRWLPNGDIDYLGRNDFQIKLRGFRIELGEIETHLIQCSGVGEAVVI 4125
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A++ P A + ++ +L+ L +YM+P + ++ P+ NGK+
Sbjct: 4126 AREDSTGDARLVAYLCPQPGAELHPTDLRQQLSRHLAEYMVPSAFVVLDVFPLTSNGKL 4184
Score = 107 bits (257), Expect = 2e-22
Identities = 59/176 (33%), Positives = 98/176 (55%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P++N +Y+LD + V G GE+ + G +ARGY+ D RFI +P + P
Sbjct: 5085 IGKPLANTRLYILDAQDQPVPIGVTGELHIGGAGVARGYLHRPDLTAERFIPDPFSADPA 5144
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++Y+TGD L G I Y GR D Q+K+RG R++ E++ + P V + VV+
Sbjct: 5145 -ARIYKTGDLARWLPDGNIDYLGRNDFQIKVRGFRIEAGEIESRLLRCPGVQDAVVIARE 5203
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A++ P+A + + +L +SL DYMIP + ++ +P+ NGK+
Sbjct: 5204 DSPGDTRLVAYLCARPDAELHPAALRQQLAASLADYMIPSAFVTLDALPLTPNGKL 5259
Score = 106 bits (255), Expect = 3e-22
Identities = 61/183 (33%), Positives = 100/183 (54%), Gaps = 7/183 (3%)
Frame = +3
Query: 18 LTVP---IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN 182
LT P IG PI+N +Y+LD R V G GE+ +AG + RGY+ D RFI +
Sbjct: 7212 LTTPTPYIGHPIANTQIYILDAQGRVVPLGVAGEIHIAGAGVVRGYLGRPDLTAERFITD 7271
Query: 183 PHNTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359
P + P A++Y+TGD G L G + Y GR D QVK+RG R++L E++ ++ V +
Sbjct: 7272 PFSGAPE-ARMYKTGDLGRWLPDGTLEYLGRNDFQVKVRGFRIELGEIETRLARCHGVHD 7330
Query: 360 CVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536
VV+ + ++A++ P+ + ++ L+ + +YMIP + ++ P+ N
Sbjct: 7331 AVVIAREDSPGDKRLVAYLLAQPDTVLEPADLRQRLSEGVAEYMIPSAFVTLDAFPLTPN 7390
Query: 537 GKV 545
GK+
Sbjct: 7391 GKL 7393
Score = 102 bits (244), Expect = 6e-21
Identities = 60/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD + V G GE+ + G +ARGY+ D RFI +P
Sbjct: 6141 VPIGRPIANTQLYILDTLGQPVPLGVAGELHIGGVGVARGYLNRPDLTAERFIPDPFINQ 6200
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LY+TGD L G + Y GR D QVK+RG R++L E++ + P V VV+
Sbjct: 6201 PG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVA 6259
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A++ P ++ +L L +YM+P + ++ P+ NGK+
Sbjct: 6260 REDSPGDTRLVAYLCPQPGVTPDPADLRQQLGQHLAEYMVPGAFVTLDAFPLTPNGKL 6317
Score = 101 bits (241), Expect = 1e-20
Identities = 57/178 (32%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD + G GE+ + G +ARGY+ D RFI +P +
Sbjct: 1873 VPIGRPIANTCIYILDAKGQPAPVGVAGEIYIGGAGVARGYLNRPDLTAERFIADPFSDS 1932
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
N A++Y+TGD G L G I Y GR D Q+K+RG R++ E++ + P V +V+
Sbjct: 1933 EN-AQIYKTGDLGRWLPDGNIEYLGRNDFQIKVRGFRIEPGEIEARLMAYPGVREALVIA 1991
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A++ P + + + L L +YM+P + ++ P+ NGK+
Sbjct: 1992 REDSPGDIRLVAYLIAQPGSELIPSVLRKALALHLAEYMVPSAFVTLDAFPLTPNGKL 2049
Score = 100 bits (239), Expect = 3e-20
Identities = 58/176 (32%), Positives = 93/176 (52%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P++N VY+L + V G GE+ + G +ARGY+ D RFI NP
Sbjct: 795 IGRPLTNTEVYILGTQGQPVPIGVTGEIYIGGAGVARGYLNRPDLTAERFITNPFVDEQE 854
Query: 204 FAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LY+TGD G G I Y GR D QVK+RG R++L E++ + P + VV+
Sbjct: 855 -ARLYKTGDLGYWRHDGSITYLGRNDFQVKLRGFRLELGEIETLLIQYPGIQEAVVILRE 913
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ P+ + + ++ +L+ L +YMIP + ++ P+ NGK+
Sbjct: 914 DIPGDKRLVAYFQAQPDTQPTPADLRLQLSQRLAEYMIPSAFVALDAFPLTPNGKL 969
Score = 99.5 bits (237), Expect = 4e-20
Identities = 59/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD + V G GE+ + G +ARGY+ D RFI +P +
Sbjct: 2932 VPIGRPIANTQLYILDTLGQPVPLGVAGELHIGGVGVARGYLNRPDLTVERFIPDPFSNQ 2991
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LY+TGD L G + Y GR D QVK+RG R++L E++ + P V VV+
Sbjct: 2992 PG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVA 3050
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A++ ++ +L L +YM+P + ++ P+ NGK+
Sbjct: 3051 REDSPGDTRLVAYLCPQLGVTPDPADLRQQLGQHLAEYMVPGAFVTLDAFPLTPNGKL 3108
>UniRef50_Q5Z1T0 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Nocardia farcinica|Rep: Putative non-ribosomal
peptide synthetase - Nocardia farcinica
Length = 1701
Score = 110 bits (264), Expect = 2e-23
Identities = 69/182 (37%), Positives = 101/182 (55%), Gaps = 8/182 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIGVP N Y Y+LDE ++ V G GE+ + G LARGY+ + RF+ +P
Sbjct: 796 VPIGVPNRNVYTYVLDEALQLVPAGVVGELYLGGDQLARGYLGRPELTAQRFVADPFT-- 853
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LYRTGD + G + + GRAD QVK+RG R++L EV+ AV+T P V +CVV+
Sbjct: 854 PG-ARLYRTGDLVRRNHFGELEFVGRADEQVKVRGFRIELGEVEAAVATHPAVGHCVVVV 912
Query: 375 YGVESSNPEILAFVTINPE----ARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNG 539
+ P + A+V + + + + A + L YM+P I +P+ VNG
Sbjct: 913 AEDPAVGPMLAAYVVPAADEIAGGEIDLEEVRAHAAAVLPQYMVPSAFAVIPEIPLTVNG 972
Query: 540 KV 545
K+
Sbjct: 973 KL 974
>UniRef50_Q2ANW8 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Bacillus weihenstephanensis KBAB4|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Bacillus weihenstephanensis KBAB4
Length = 4080
Score = 110 bits (264), Expect = 2e-23
Identities = 61/179 (34%), Positives = 101/179 (56%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197
+P+G P++N +Y+LDENM + G GE+ + G LARGY+ +FI +P+ +
Sbjct: 2297 IPVGKPLANRRIYILDENMHPLPIGVKGEIFIGGIPLARGYINNSKLTKDKFIRDPY--Y 2354
Query: 198 PNFAK-LYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
N+ K LY+TGD G +L G I GR D Q KIRGHR+D+ E++ ++ + N +V+
Sbjct: 2355 HNYGKMLYKTGDMGKLLCDGNIEVLGRKDDQTKIRGHRIDIGEIEVVLNKCDNIKNSIVV 2414
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+++ ++AF + +I L L +YMIP I++ ++P+ NGK+
Sbjct: 2415 VKNGVANDKYLVAFYDSPSNGTNNQCSIRGFLRKKLPEYMIPSYFIQLGSLPLSPNGKI 2473
Score = 100 bits (240), Expect = 2e-20
Identities = 59/179 (32%), Positives = 103/179 (57%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TV +G PISN Y+LD++ G PGE+ +AG + RGY+ + +F+++P N
Sbjct: 771 TVSLGRPISNVRCYILDKDKNISPIGVPGELYIAGDGVGRGYLNLPEFTNEKFMNDPFN- 829
Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
PN ++Y+TGD G L G I + GR D QVKIRG+R++L E+ + + +++ V+
Sbjct: 830 -PN-DRMYKTGDLGRWLPNGEIEFLGREDHQVKIRGYRIELSEIHNLILKRNYIEDVAVI 887
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + + I A++ + + M + ++ L L DYM+P I++E++P+ GK+
Sbjct: 888 DWEINNGKKVICAYIVSHVQVNM--EELKGFLAKELPDYMLPSYYIQLESLPLTSIGKL 944
Score = 90.6 bits (215), Expect = 2e-17
Identities = 53/176 (30%), Positives = 95/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+ N +++LD + V G GE+C+ G + GY+ D +FI H
Sbjct: 3349 IGKPVDNTKIFILDRGQKLVPLGMAGEICIGGVGVTEGYLNQIDLNSEKFITVSPLGHEK 3408
Query: 204 FAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
KLYRTGD G L + + GR D+Q+KIRG+RV+L+E++ + + + +V+
Sbjct: 3409 I-KLYRTGDLGRLTCHQEVEFLGRIDNQLKIRGYRVELEEINSVLLQHDMILDAIVVPKK 3467
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ +N + A++ + + + I L+S + YM+P + I+++ +P+ NGK+
Sbjct: 3468 DKENNNILCAYIVL--KENENGWGIREYLSSKIPYYMMPSIFIKLDRIPLTPNGKL 3521
>UniRef50_UPI000038CDA7 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide
synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 1075
Score = 109 bits (263), Expect = 3e-23
Identities = 67/184 (36%), Positives = 97/184 (52%), Gaps = 9/184 (4%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVP+G P++N +YLLDE ++ V G PGE+ + G LARGY+ D +FI NP
Sbjct: 769 TVPLGRPLANTQIYLLDEQLQPVPVGVPGELYIGGAGLARGYLNQSDLTAAQFIPNPFAD 828
Query: 195 HPNFA-----KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVD 356
A +LY+TGD L G I + GR D QVKIRG R++L E++ + P V
Sbjct: 829 TGLIASKPGSRLYKTGDLARYLPDGNIEFLGRVDHQVKIRGFRIELGEIETTLCQHPQVQ 888
Query: 357 NCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLV 533
V E N ++A+V + +S + L L +YM+P I ++ +P+
Sbjct: 889 QAVASIREEEFGNKSLVAYVVPKQQQTLSVSELYRFLREKLPEYMMPATFIMLKALPLTP 948
Query: 534 NGKV 545
NGKV
Sbjct: 949 NGKV 952
>UniRef50_Q5YPH7 Cluster: Putative non-ribosomal peptide synthetase;
n=2; cellular organisms|Rep: Putative non-ribosomal
peptide synthetase - Nocardia farcinica
Length = 8426
Score = 109 bits (263), Expect = 3e-23
Identities = 66/180 (36%), Positives = 105/180 (58%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVP+G P+ N Y+LD +R V G PGE+ +AG LARGY+ D RF+ +P +
Sbjct: 2581 TVPMGRPVWNTRAYVLDARLRPVPVGVPGELYLAGAQLARGYLGRADLTGDRFVADPFD- 2639
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD ++ G + Y GR D QVK+RG R++L E++ A+ +P V+ VL
Sbjct: 2640 EPG-DRMYRTGDLVRWNRDGELEYLGRTDFQVKLRGLRIELGEIETALLAVPGVEQAAVL 2698
Query: 372 CYGVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ P ++A+V + P + A+ + AEL L YM+P V + ++ +P+ +GK+
Sbjct: 2699 VRDDHGTGPRLVAYVVGVEP---VPAEGLRAELARRLPGYMVPGVYVALDALPLNASGKL 2755
Score = 108 bits (259), Expect = 9e-23
Identities = 61/177 (34%), Positives = 99/177 (55%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG P + VY+LD+ + V G GE+ + G LARGY R D RF+ +P P
Sbjct: 7887 PIGAPEAGTRVYVLDDRLHPVPTGVVGELYLGGAQLARGYHRRPDLTAERFVADPFGA-P 7945
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+LYRTGD +G +++ R D QVK+RG+R++L E++HA+ P V VVL +
Sbjct: 7946 G-ERLYRTGDLVRWTAEGQLVFVQRRDFQVKVRGYRIELTEIEHALRAHPAVAEAVVLAH 8004
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
G + ++ +VT + +++ A L +L YM+P ++ ++ +P+ NGK+
Sbjct: 8005 GAGGAEAMLVGYVT--TRTPVDTEDLRAALAGTLPGYMVPAALVRLDALPLTANGKL 8059
Score = 97.1 bits (231), Expect = 2e-19
Identities = 63/182 (34%), Positives = 92/182 (50%), Gaps = 8/182 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P N+ VY+LD + G PGE+ +AG LARGY D RF+ NP
Sbjct: 1512 VPIGEPEWNSQVYVLDARLHPAPIGVPGELYLAGDQLARGYHGRVDLTADRFVANPFGR- 1570
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G ++Y GR D QVK RG R++L E++ A+ P V
Sbjct: 1571 -GGERMYRTGDLVRWSSDGELIYLGRVDFQVKFRGQRIELAEIETALLAEPEVGQAAAAL 1629
Query: 375 YGVESSNPE----ILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539
+ E + E ++ +V P A + + A LT L YM+P ++E+ P+ +G
Sbjct: 1630 WSRERGSGEPGEHLVGYVVAAPGAEVDIDRLRAALTRRLPAYMVPTALVELAEFPLNTSG 1689
Query: 540 KV 545
K+
Sbjct: 1690 KL 1691
Score = 96.7 bits (230), Expect = 3e-19
Identities = 59/178 (33%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P+ N + +LD +R V G PGE+ +AG LA GYV D RF+ +P
Sbjct: 4704 VPIGRPVFNTRLLVLDARLRPVPVGVPGELYLAGAQLALGYVARPDLTAERFVADPFGEP 4763
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ ++YRTGD ++ G + Y GR D QVK+RG R++L E++ A++ +P ++ VL
Sbjct: 4764 GD--RMYRTGDLVRWNRDGELEYLGRTDFQVKLRGLRIELGEIETALTALPGIEQAAVLV 4821
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
G ++ ++ + + + A + A L + L YM+P + ++ +PV +GK+
Sbjct: 4822 RGTAGGEDTLVGYL-VATDPDLDA--VRAALAARLPAYMVPAAFVVLDELPVNSSGKL 4876
Score = 95.5 bits (227), Expect = 7e-19
Identities = 57/178 (32%), Positives = 91/178 (51%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V +GVP++ +LD +R V G PGE+ + G LARGY G RF+ +PH
Sbjct: 6808 VELGVPLAGMSAVVLDARLRPVPAGVPGELYLRGHGLARGYHARPGLTAGRFVADPHG-- 6865
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +LYRTGD G + Y GR D QVK+RG R++L E+D ++ P V V +
Sbjct: 6866 PAGGRLYRTGDLACWTADGALRYLGRGDHQVKVRGLRIELGEIDTVLAAHPSVRAAVTVG 6925
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ V + ++++V + + A +L YM+P + + + +P+ GK+
Sbjct: 6926 HAVAGEDVALVSYVVAAQGEIVDTAALLAHAARALPPYMVPAAVTVLDRLPLTPVGKL 6983
Score = 94.7 bits (225), Expect = 1e-18
Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V IG P N VY+LD +R V G PGE+ +AG LARGY R G RF+ +P
Sbjct: 3648 VAIGRPCWNTRVYVLDTRLRPVPIGVPGELYLAGNQLARGYHRRPGPTAERFVADPFGV- 3706
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P + +YRTGD ++ G ++Y GR D QVK+RG R++L E++ A++ +P V N V
Sbjct: 3707 PG-SLMYRTGDLVRWNRDGDLIYLGRNDFQVKLRGQRIELGEIEAALAAVPGVANAAVRV 3765
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++ +V+ + +SA + L L YM+P ++ + +P+ GK+
Sbjct: 3766 VADSAGRDALVGYVSGDD---LSAAAVLDVLRDRLPGYMVPAHLVVLAEMPLTTVGKL 3820
Score = 90.2 bits (214), Expect = 3e-17
Identities = 64/185 (34%), Positives = 97/185 (52%), Gaps = 9/185 (4%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHN 191
+TVPIG +N + +LDE++R V G GE+ +AG LARGYV G RF+ NPH
Sbjct: 441 VTVPIGTVADDNELLVLDESLRPVPTGVVGELYLAGVQLARGYVARPGLTAERFVANPHG 500
Query: 192 THPNFAKLYRTGDF----GILDKG--VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353
P ++YRTGD G D G + Y GR D QVK+RG R++L EV+ A+ V
Sbjct: 501 A-PG-ERMYRTGDLVRWGGGADGGPLELEYLGRIDFQVKLRGLRIELGEVEAALLRSQQV 558
Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVL 530
V+ + + + L + + + A L +YM+P ++++ + +PV
Sbjct: 559 AQAAVVVR--QHAGGDHLVGYVVPAGGPVDPAAVLAVAREHLPEYMVPALVQVLDELPVN 616
Query: 531 VNGKV 545
NGK+
Sbjct: 617 ANGKL 621
Score = 80.2 bits (189), Expect = 3e-14
Identities = 58/185 (31%), Positives = 91/185 (49%), Gaps = 12/185 (6%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHNTH 197
PIG P N+ VY+LD +R G GE+ +AG LARGY G+ RF+ NP
Sbjct: 5760 PIGNPEWNSRVYVLDSRLRPTLPGVAGELYLAGVQLARGY-HGRPALTADRFVANPFGAA 5818
Query: 198 PNFAKLYRTGDFGIL----DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
++YRTGD D ++Y GR D QVK RG R++L E++ ++ +P V
Sbjct: 5819 GE--RMYRTGDLVRWETRGDTAELVYLGRTDFQVKFRGQRIELGEIEAVLAAVPGVAGAA 5876
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNI----EAELTSSLTDYMIP-QVIEIETVPVL 530
G ++ ++ + PEA + A +L YM+P ++ ++ P+
Sbjct: 5877 ARVLG-----EHLVGYLLVAPEAADDHDAVLARARAAAHEALPAYMVPGALLALDEFPLN 5931
Query: 531 VNGKV 545
V+GK+
Sbjct: 5932 VSGKL 5936
>UniRef50_Q3M3K1 Cluster: Amino acid adenylation precursor; n=2;
Nostocaceae|Rep: Amino acid adenylation precursor -
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length = 1436
Score = 109 bits (263), Expect = 3e-23
Identities = 65/178 (36%), Positives = 101/178 (56%), Gaps = 6/178 (3%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH--NTH 197
IG PI+N +Y+LD+ ++ V G PGEV ++G +A+GY R D RFI +P NTH
Sbjct: 863 IGQPIANTQIYILDQLLQPVPVGAPGEVYISGVGVAKGYFRRTDLTSERFIPHPFSDNTH 922
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LY+TGD L G I Y GR D+QVKI G VDL++++ + + VV+
Sbjct: 923 E---RLYKTGDLARYLPDGNIEYLGRTDNQVKICGVCVDLEQIEALLHQHQAITQAVVIA 979
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
V S +++A++ PE + +++ L+ + Y IP I +E++PV NG+V
Sbjct: 980 TEVTSGEKQLVAYLVTQPEQTPTIDDLQTFLSQKIPHYWIPSDFIFLESLPVNTNGQV 1037
>UniRef50_Q1RS73 Cluster: NRPS/PKS protein; n=5; Bacteria|Rep:
NRPS/PKS protein - Bacillus amyloliquefaciens
Length = 4982
Score = 109 bits (263), Expect = 3e-23
Identities = 66/175 (37%), Positives = 95/175 (54%), Gaps = 3/175 (1%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFA 209
IG PI+N VY++D + V EG PGE+C+AG LARGY + H +
Sbjct: 1452 IGRPIANTRVYIMDSGLNPVLEGVPGELCIAGDGLARGYFNKPELTDKAFVSHRLELG-S 1510
Query: 210 KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVE 386
KLY+TGD L G I Y GR D+QVKIRG+R++ +++ ++ P V VV+
Sbjct: 1511 KLYKTGDMARFLPGGRIEYMGRMDTQVKIRGYRIEPGDIESRLNAHPAVQESVVVVNN-H 1569
Query: 387 SSNPEILAF-VTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
S N ++ AF + N E SAK + + +L YM P + +E +P+ NGKV
Sbjct: 1570 SGNEKLCAFYIRKNGEPLPSAKELRKHMKQALPAYMAPASFVRLEELPLTPNGKV 1624
Score = 52.0 bits (119), Expect = 9e-06
Identities = 48/185 (25%), Positives = 79/185 (42%), Gaps = 11/185 (5%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
V IG+PI + + D+ + V EGE G V+G + GY D + +
Sbjct: 374 VEIGLPIPGFNMRITDDRNQVVEEGEIGRFQVSGLTVTSGYYERPDLNESVFTEDG---- 429
Query: 204 FAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGV 383
+ TGD G L +G + GR + I G ++ AV +P ++ V
Sbjct: 430 ---WFETGDLGFLREGRLTITGRTKDAIIINGVNYYSHAIESAVEELPEIETSYTAACAV 486
Query: 384 ---ESSNPEI-LAFVTINP--EARMS--AKNIEAELTSSL---TDYMIPQVIEIETVPVL 530
+S+ E+ + FVT P E RM+ +I +T + DY++P + E +P
Sbjct: 487 RPNQSTTDELAIFFVTSVPLDENRMTKLLHHIHQHVTQRIGVTPDYLLP--VAKEDIPKT 544
Query: 531 VNGKV 545
GK+
Sbjct: 545 AIGKI 549
>UniRef50_Q0LLT6 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2844
Score = 109 bits (263), Expect = 3e-23
Identities = 64/178 (35%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI+N +Y+LD ++ V G GE+ + G + RGY R D RF+ +P
Sbjct: 2298 LPIGRPIANTQMYVLDPRLQLVPIGVVGELYIGGAGVGRGYHRRPDLTAERFVPDPFGGQ 2357
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LY+TGD G IL G + GR D QVK+RG R++L+E++ A+ V VV
Sbjct: 2358 PG-ARLYKTGDLGRILADGTLECLGRVDHQVKVRGFRIELEEIEAALLRQAGVREAVVAA 2416
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
ES + ++ A+V P+ + ++ L L YM P ++ I+ +P+ NGKV
Sbjct: 2417 RRQESGDIQLAAYVVAAPDNPLQIPTLKQSLQELLPAYMAPSHIMLIDELPLTSNGKV 2474
Score = 90.6 bits (215), Expect = 2e-17
Identities = 54/179 (30%), Positives = 93/179 (51%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
+ P+G P+ V LLD+ R V G GE+ + G ++RGY R++ +P +
Sbjct: 1231 SAPLGAPLEATQVALLDDQGRVVPVGIAGELYLGGAGVSRGYFGRPALTAERYLPDPFSG 1290
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A++YRTGD + G++ Y GR + QVK+RG R++L EV+ A+S V V+
Sbjct: 1291 VLG-ARMYRTGDRALYRADGMLEYRGRVEQQVKLRGFRIELGEVEAALSEQAAVQEAAVV 1349
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+P ++ +V + + ++A L L +YM+P QV+ + +P +GK+
Sbjct: 1350 IKASPRGDPTLVGYVVARAGEALDSTTVQAALRERLPEYMVPSQVVVLLGLPRTSSGKL 1408
Score = 83.4 bits (197), Expect = 3e-15
Identities = 54/177 (30%), Positives = 90/177 (50%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200
P+G I N+ Y+LD + V G GE+ + G ++RGY R++ +P +
Sbjct: 167 PLGRTIDNSEGYVLDGFQQPVPVGIAGELYLGGAGVSRGYFGRPALTAERYLPDPFSGVL 226
Query: 201 NFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A++YRTGD G + Y GR D QVK+RG R++L EV+ A+S V V+
Sbjct: 227 G-ARMYRTGDRVRRQADGTLEYLGRMDRQVKLRGFRIELGEVEAALSEQAAVQEAAVVIK 285
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+P ++ +V + + ++A L L +YM+P QV+ + +P +GK+
Sbjct: 286 ASPRGDPTLVGYVVARAGEALDSTTVQAALRERLPEYMVPSQVVVLLGLPRTSSGKL 342
>UniRef50_A3DGP7 Cluster: Amino acid adenylation domain; n=1;
Clostridium thermocellum ATCC 27405|Rep: Amino acid
adenylation domain - Clostridium thermocellum (strain
ATCC 27405 / DSM 1237)
Length = 625
Score = 109 bits (263), Expect = 3e-23
Identities = 66/179 (36%), Positives = 103/179 (57%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHNT 194
VPIG PI N Y+LDE+++ V GE GE+ + G + RGY GK ++I NP +
Sbjct: 332 VPIGYPIDNTQAYILDEDLKPVPFGEVGELYIGGDGVGRGYF-GKPELTSEKYIQNPFSD 390
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ + ++ +TGD L G I Y GRAD Q+K+RG R++L E++ A+ P V VV+
Sbjct: 391 NQS-DRICKTGDLARFLPDGSIEYLGRADFQIKLRGFRIELGEIESAIEKHPWVQQAVVV 449
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E + I+A+ E S++++ + L ++L DYMIP ++I+ P+ NGKV
Sbjct: 450 KDNGE-GDQHIVAYFRTKSEQVPSSEDMRSFLKNTLPDYMIPSFFVQIDEFPLTPNGKV 507
>UniRef50_Q3M1N0 Cluster: Amino acid adenylation; n=2; Bacteria|Rep:
Amino acid adenylation - Anabaena variabilis (strain ATCC
29413 / PCC 7937)
Length = 2867
Score = 109 bits (262), Expect = 4e-23
Identities = 63/176 (35%), Positives = 96/176 (54%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI + VY+LD++ + V G GE+ + G LA+GY+ D +FI +P + P+
Sbjct: 824 IGRPIPDLQVYILDQHQQLVPIGVSGEMYIGGGGLAKGYLNRPDLTTEKFIPHPFSNQPD 883
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LY++GD L G I Y GR D QVKIRG R++L E+ ++ P V VVL
Sbjct: 884 -ARLYKSGDLARYLPNGDIEYLGRIDHQVKIRGFRIELGEIAGILTQHPSVQETVVLAKE 942
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
S ++A+V + + + L L DYM+P V + +E +P+ NGK+
Sbjct: 943 TSSGEKYLVAYVVFRHQQTPTTSQLRNFLKKQLPDYMLPSVFVVVEALPLTANGKL 998
Score = 79.0 bits (186), Expect = 7e-14
Identities = 46/142 (32%), Positives = 81/142 (57%), Gaps = 4/142 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPH 188
+++PIG PI N +Y+L+ + + V G GE+ + G +ARGY+ GK +FI +
Sbjct: 1892 ISIPIGRPIHNTQIYILNSDGKLVPVGVTGELYIGGDGIARGYL-GKPQLTAEKFIPDFF 1950
Query: 189 NTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
+ P A+LY+TGD G I + GR+D QVKIRG R++L E++ + P +
Sbjct: 1951 SDEPG-ARLYKTGDLARYRPDGNIEFLGRSDRQVKIRGFRIELGEIEAVLEQHPTIREVA 2009
Query: 366 VLCYGVESSNPEILAFVTINPE 431
V+ ++ + ++A++ +P+
Sbjct: 2010 VVSREIQ-GDLRLVAYIVPSPQ 2030
>UniRef50_Q2SKF9 Cluster: Non-ribosomal peptide synthetase modules and
related protein; n=1; Hahella chejuensis KCTC 2396|Rep:
Non-ribosomal peptide synthetase modules and related
protein - Hahella chejuensis (strain KCTC 2396)
Length = 1756
Score = 109 bits (262), Expect = 4e-23
Identities = 65/178 (36%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNTH 197
V IG PI N ++++D+ +R + G PGE+C+AG LARGY + RF+ NP N
Sbjct: 582 VTIGSPIDNTQIHIVDKQLRRLPIGVPGELCIAGVGLARGYHALPEVTADRFVANPENAS 641
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ YRTGD L G I Y GR D QVK+RG R++LQE+D + + V + V L
Sbjct: 642 ERW---YRTGDLARWLGNGEIEYLGRLDHQVKVRGFRIELQEIDAVLRSHSAVRDAVTLV 698
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + +++A+VT N E + + + + YM+P VI +E +P+ NGK+
Sbjct: 699 HRAAGLD-KLVAYVTANGEP--EPETLRQHVAGQVPAYMVPDMVIVLEQMPLSPNGKL 753
>UniRef50_Q04747 Cluster: Surfactin synthetase subunit 2; n=9;
Bacillus|Rep: Surfactin synthetase subunit 2 - Bacillus
subtilis
Length = 3587
Score = 109 bits (262), Expect = 4e-23
Identities = 63/179 (35%), Positives = 102/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++PIG PI N+ Y++DE G PGE+CV G +ARGYV + +F+ +P
Sbjct: 773 SIPIGKPIGNSTAYIMDEQQCLQPIGAPGELCVGGIGVARGYVNLPELTEKQFLEDPF-- 830
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD L G I + GR D+QVK+RG R++L E++ ++ V V+
Sbjct: 831 RPG-ERIYRTGDLARWLPDGNIEFLGRIDNQVKVRGFRIELGEIETKLNMAEHVTEAAVI 889
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ EI A+ T + E +S + L+ SL DYM+P +I+++++P+ NGK+
Sbjct: 890 IRKNKADENEICAYFTADREVAVS--ELRKTLSQSLPDYMVPAHLIQMDSLPLTPNGKI 946
Score = 104 bits (250), Expect = 1e-21
Identities = 67/178 (37%), Positives = 100/178 (56%), Gaps = 3/178 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194
++ IG I+N VY+L E + EG GE+CVAG LARGY+ +D RF+ +P
Sbjct: 2848 SLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAKRFVADPFV- 2906
Query: 195 HPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD G I Y GR D QVK+RG+R++L E++ ++ + V++ V
Sbjct: 2907 -PG-ERMYRTGDLVKWVNGGIEYIGRIDQQVKVRGYRIELSEIEVQLAQLSEVEDRAVTR 2964
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ N I A+VT PE + +++ L +L DYMIP + + +PV NGKV
Sbjct: 2965 VKDKGGNTAIAAYVT--PET-ADIEALKSTLKETLPDYMIPAFWVTLNELPVTANGKV 3019
Score = 93.5 bits (222), Expect = 3e-18
Identities = 56/175 (32%), Positives = 98/175 (56%), Gaps = 4/175 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+N +L+E ++ V G G++ + G LARGY+ RF+ NP++ P
Sbjct: 1821 IGRPIANAGALVLNEALKLVPPGASGQLYITGQGLARGYLNRPQLTAERFVENPYS--PG 1878
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+ +Y+TGD L G + + GRAD QVKIRG+R++L E++ + ++ + VVL
Sbjct: 1879 -SLMYKTGDVVRRLSDGTLAFIGRADDQVKIRGYRIELGEIETVMLSLSGIQEAVVLAVS 1937
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542
E E+ A+ T + + + + +L+ +L +MIP ++++ +P+ NGK
Sbjct: 1938 -EGGLQELCAYYTSDQD--IEKAELRYQLSLTLPSHMIPAFFVQVDAIPLTANGK 1989
>UniRef50_O68008 Cluster: Bacitracin synthetase 3 (BA3) [Includes:
ATP-dependent isoleucine adenylase (IleA) (Isoleucine
activase); ATP-dependent D-phenylalanine adenylase
(D-PheA) (D-phenylalanine activase); ATP-dependent
histidine adenylase (HisA) (Histidine activase);
ATP-dependent D-aspartate adenylase (D-AspA) (D-aspartate
activase); ATP-dependent asparagine adenylase (AsnA)
(Asparagine activase); Aspartate racemase (EC 5.1.1.13);
Phenylalanine racemase [ATP hydrolyzing] (EC 5.1.1.11)];
n=3; Bacillus|Rep: Bacitracin synthetase 3 (BA3)
[Includes: ATP-dependent isoleucine adenylase (IleA)
(Isoleucine activase); ATP-dependent D-phenylalanine
adenylase (D-PheA) (D-phenylalanine activase);
ATP-dependent histidine adenylase (HisA) (Histidine
activase); ATP-dependent D-aspartate adenylase (D-AspA)
(D-aspartate activase); ATP-dependent asparagine
adenylase (AsnA) (Asparagine activase); Aspartate
racemase (EC 5.1.1.13); Phenylalanine racemase [ATP
hydrolyzing] (EC 5.1.1.11)] - Bacillus licheniformis
Length = 6359
Score = 109 bits (262), Expect = 4e-23
Identities = 65/179 (36%), Positives = 103/179 (57%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+PIG P++N V ++DE + + G PGE+C+AG L++GY+ ++ +FI PH
Sbjct: 768 TIPIGSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFI--PHPF 825
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +LY+TGD L G I + GR D QVKIRG R++L E++ + ++ +V
Sbjct: 826 IPG-ERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVT 884
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E S P I A++T N E +S ++ L L +YMIP ++++ +P+ NGKV
Sbjct: 885 VREDEESRPYICAYITANRE--ISLDELKGFLGEKLPEYMIPAYFVKMDKLPLTKNGKV 941
Score = 109 bits (262), Expect = 4e-23
Identities = 63/176 (35%), Positives = 95/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI N Y+LDENM+ + EG GE+C+AG + GYV D +FI NP H
Sbjct: 4351 IGTPIHNTNAYVLDENMKLLPEGVYGELCIAGAGVTGGYVNRPDETKEKFIENPFAPH-- 4408
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
K+YRTGD L G I AGR D+QVK+RG+R++ +E+ + + + +
Sbjct: 4409 -TKMYRTGDLARRLSDGNIELAGRIDTQVKVRGYRIEPEEIKNRLLAHDDIKEAFIAARE 4467
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ A+ T +A + ++I L L +YMIP ++IE +P+ NGK+
Sbjct: 4468 DHKGAKQLCAYFT--ADAELPFEDIRTYLMHELPEYMIPSSFVQIEKMPLSANGKI 4521
Score = 108 bits (260), Expect = 7e-23
Identities = 63/178 (35%), Positives = 101/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V IG PISN+ VY+L+ N + + G PGE+C++G LARGY+ D +F+ NP
Sbjct: 3306 VVIGRPISNHKVYILNHNQQLLPLGTPGELCLSGEGLARGYLNRPDLTLEKFVPNPF--A 3363
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +YRTGD L G I Y GR D QVKIRG R++L E+++ + I +D V+
Sbjct: 3364 PG-ESMYRTGDLARFLPDGQIEYLGRIDHQVKIRGFRIELGEIENQLLKIEGIDAAAVMA 3422
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++ + A++ + A ++ ++ L L DYM+P ++++ +P+ NGK+
Sbjct: 3423 REDQAGGKYLCAYIVADKAAGVA--DVRKCLLKELPDYMVPSYFVKLDQLPLTANGKI 3478
Score = 98.7 bits (235), Expect = 8e-20
Identities = 59/176 (33%), Positives = 96/176 (54%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+N VY+LD+N + V G GE+CV G +LARGY+ + +FI +P +
Sbjct: 1803 IGSPIANTNVYVLDQNQKPVPTGVVGELCVGGMSLARGYLNRPELTAEKFISHP---FAS 1859
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LYRTGD L G + + GR D QVKIRG+R++L E+++ + + +D V+
Sbjct: 1860 GERLYRTGDLARWLPDGHLEFLGRIDHQVKIRGYRIELGEIENQLLKLDKIDEAAVIARK 1919
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + + A++ + ++ I L L YMIP + ++ +P+ N KV
Sbjct: 1920 DDDHSDYLCAYIVSKED--WTSTEISEWLEKELPHYMIPAYFVRLDKLPLTSNDKV 1973
Score = 98.3 bits (234), Expect = 1e-19
Identities = 59/180 (32%), Positives = 101/180 (56%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
++VPIG P SN +Y+LDE G GE+ ++G +A+GY+ + +F+ NP
Sbjct: 5853 VSVPIGKPASNVQLYILDERQEVQPVGIAGELYISGDGVAKGYLNKPELTSEKFLPNPF- 5911
Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
P ++YRTGD + G I Y GR D QVKIRG+R++L E++H + + V
Sbjct: 5912 -LPG-ERMYRTGDLAKMRPDGHIEYLGRIDHQVKIRGYRIELGEIEHQLLRHSDIKEAAV 5969
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ +N ++L ++ E ++ K+I+ L L +YM+P +++++ +P+ NGKV
Sbjct: 5970 AA-KTDQNNDQVLCAYVVS-ERDITQKDIKTFLAKELPEYMVPSYLLKLDELPLTPNGKV 6027
>UniRef50_Q84DH9 Cluster: Peptide synthase; n=3; Streptomyces|Rep:
Peptide synthase - Streptomyces ansochromogenes
Length = 677
Score = 109 bits (261), Expect = 5e-23
Identities = 65/179 (36%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PI N Y+LD+ +R V GEPGE+ + G +A GY+ RF+ +P +
Sbjct: 395 SVPIGRPIDNVRTYVLDDALRPVPAGEPGELFIGGAGVAVGYLNAPQTTAERFLPDPFSG 454
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++LYRTGD D G + + GR D QVK+RG+R++L E++ ++ V CV L
Sbjct: 455 VPG-SRLYRTGDLVRADADGCLEFLGRRDHQVKLRGYRIELGEIEAVLTEHEDVRACVAL 513
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
G + + ++ FVT A A + A L L YMIP + + + P+ NGK+
Sbjct: 514 VTG-DGPDSALVCFVTAGGRAAPPAAELIAHLRGRLPWYMIPTAVHVLDAFPLTPNGKI 571
>UniRef50_Q1RS70 Cluster: Hybrid NRPS/PKS; n=4; cellular
organisms|Rep: Hybrid NRPS/PKS - Bacillus
amyloliquefaciens
Length = 5433
Score = 109 bits (261), Expect = 5e-23
Identities = 70/178 (39%), Positives = 99/178 (55%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI N +Y++DE + V +G GE+CVAG LARGY + FI NP +
Sbjct: 807 PIGKPIHNTRLYIVDEKLSPVPDGVAGELCVAGAGLARGYYNQPELTAASFIDNPFS--- 863
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP-CVDNCVVLC 374
KLY+TGD L G I YAGR DSQVKIRG R++L ++ +S P +D VV+
Sbjct: 864 EGEKLYKTGDLARWLPDGNIEYAGRIDSQVKIRGFRIELGAIETKLSEHPDILDQAVVV- 922
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ + +++A+ T K + L SSL DYM P I ++ +P+ +GKV
Sbjct: 923 -QEKNGHKKLIAYYTARSGHTADEKALRNHLLSSLPDYMAPAHFIRLDALPLTPSGKV 979
>UniRef50_A0ZL90 Cluster: Non-ribosomal peptide synthase; n=1;
Nodularia spumigena CCY 9414|Rep: Non-ribosomal peptide
synthase - Nodularia spumigena CCY 9414
Length = 1518
Score = 109 bits (261), Expect = 5e-23
Identities = 58/180 (32%), Positives = 103/180 (57%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
+ + IG I++ +Y+LD ++ V G PGE+ +AG LARGY+ D +FI NP +
Sbjct: 766 MKISIGQAIAHTQIYILDHYLQPVPIGVPGELHIAGVGLARGYLNQPDLTAQKFIPNPFS 825
Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
N ++LY+TGD G L G I + GR D+QVKIRG R++L+E++ + P + +
Sbjct: 826 NDTN-SRLYKTGDLGRYLPDGNIEFLGRIDNQVKIRGFRIELEEIETTIVQHPQIQQAIA 884
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A++ + + +++ I L L +YMIP + + ++++P+ NGK+
Sbjct: 885 IVREDIPGTKRLVAYIVPHQQHSLNSNEIWEYLKHKLPEYMIPAIFVFLDSLPLTPNGKI 944
>UniRef50_Q8GN23 Cluster: Peptide synthetase; n=1; Fischerella sp.
CENA19|Rep: Peptide synthetase - Fischerella sp. CENA19
Length = 582
Score = 108 bits (260), Expect = 7e-23
Identities = 66/185 (35%), Positives = 102/185 (55%), Gaps = 10/185 (5%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNP--- 185
TV IG P++N +Y+LDE M+ + G PGE+CV+G + GY + ++ F+ NP
Sbjct: 268 TVSIGKPLANLNLYILDEQMQLLPIGVPGEICVSGIGVGEGYWKNEEKTNLSFVPNPFAD 327
Query: 186 -HNTHPNFAK--LYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353
P + +Y+TGD G L G I + GR D QVKIRG RV+L EV+ +S P V
Sbjct: 328 ARKKLPENRRDLIYKTGDLGRWLPDGNIEFLGRIDHQVKIRGFRVELGEVETFLSQHPNV 387
Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVL 530
+V+ + E N +++A+V E S + L L D+M+P + +E++P+
Sbjct: 388 RENIVIVHQEEPGNLQLVAYVVAKTEPVPSISELRNFLKEKLPDHMLPSTFVMLESLPIA 447
Query: 531 VNGKV 545
+GKV
Sbjct: 448 PSGKV 452
>UniRef50_Q84BC7 Cluster: NcpB; n=3; Cyanobacteria|Rep: NcpB - Nostoc
sp. ATCC 53789
Length = 4803
Score = 108 bits (260), Expect = 7e-23
Identities = 69/201 (34%), Positives = 105/201 (52%), Gaps = 26/201 (12%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVPIG PISN +Y+LD+N++ V G PGE+ + G LA+GY+ + +FI NP +
Sbjct: 1894 TVPIGRPISNTQIYILDQNLQPVPVGVPGELHIGGAGLAKGYLNRPELTQEKFIPNPFSG 1953
Query: 195 HPNFA----------------------KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHR 305
+LY+TGD L G I Y GR D+QVKIRG R
Sbjct: 1954 SRRAGEQRSRGAGERRRKIVQSPVASPRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFR 2013
Query: 306 VDLQEVDHAVSTIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTD 485
++L E++ A+S V VV+ + +++++ + PE + K + + L L D
Sbjct: 2014 IELGEIEAALSQHKDVQTSVVIVREDIPGDKRLVSYIVLQPEQTTTVKELRSFLKEKLPD 2073
Query: 486 YMIPQVIEI-ETVPVLVNGKV 545
YM+P I I E++P+ NGK+
Sbjct: 2074 YMVPSAIAILESLPLTSNGKI 2094
Score = 99 bits (238), Expect = 3e-20
Identities = 72/207 (34%), Positives = 106/207 (51%), Gaps = 31/207 (14%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV---------------- 149
L PIG PISN +Y+LD+ ++ V G PGEV +AG LARGY+
Sbjct: 3021 LLPPIGRPISNTQIYILDKYLQPVPIGVPGEVYIAGVLLARGYLNRPELTQEKFIQNPFG 3080
Query: 150 ----------RGKDPHRFIHNPHNTHPNFA--KLYRTGDFG-ILDKGVILYAGRADSQVK 290
RG + F PH+ P+ + +LY+TGD L G I Y GR D+QVK
Sbjct: 3081 GSRGAGEQGSRGAEEQSFPSAPHSLCPSASSERLYKTGDLARYLPDGNIEYLGRIDNQVK 3140
Query: 291 IRGHRVDLQEVDHAVST-IPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAEL 467
IRG R++L E++ +S I +C V+ + ++A++ PE R+S + + L
Sbjct: 3141 IRGFRIELGEIEAVLSQHINVQASCAVVREDT-PGDKRLVAYIVPQPEQRVSVNVVRSFL 3199
Query: 468 TSSLTDYMIPQVIEI-ETVPVLVNGKV 545
L +YM+P I I E +P+ NGK+
Sbjct: 3200 KEKLPEYMLPSAIVILEALPITSNGKL 3226
Score = 94.7 bits (225), Expect = 1e-18
Identities = 66/197 (33%), Positives = 99/197 (50%), Gaps = 22/197 (11%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP--- 185
T+PIG PISN +YLLD ++ V G PGE+ + G LAR Y+ + + I NP
Sbjct: 801 TIPIGQPISNTQIYLLDSQLQPVGIGVPGELYIGGDGLAREYLNRTELTQEKLIQNPFGG 860
Query: 186 -------------HNTHPNFA--KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQ 317
+ P+ + +LY+TGD L G I Y GR D QVKIRG R++L
Sbjct: 861 SRGAGEQGSKGAEEQSFPSASSERLYKTGDKARYLSDGNIEYLGRIDDQVKIRGLRIELG 920
Query: 318 EVDHAVSTIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP 497
E++ +S V V+ + ++A++ + + + + I L + L DYMIP
Sbjct: 921 EIEAVLSQHSDVQVSCVIVREDTPGDKRLVAYIVTHQDCQPTMGEIRQFLKAKLPDYMIP 980
Query: 498 QVIEI-ETVPVLVNGKV 545
I I E+ P+ NGK+
Sbjct: 981 SAIVILESFPLTPNGKI 997
Score = 87.4 bits (207), Expect = 2e-16
Identities = 62/198 (31%), Positives = 95/198 (47%), Gaps = 24/198 (12%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH--- 188
+ IG ++N VY+LDEN++ V G PGE+ + G LARGY+ + +FI NP
Sbjct: 4104 ISIGKAVANTQVYILDENLQLVPVGVPGELHIGGAGLARGYLNRPELTQEKFIPNPFAGS 4163
Query: 189 -----------NTHPNFA------KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDL 314
PN +LY+TGD L G I Y GR D+Q+KIRG R+++
Sbjct: 4164 RGAGEQGSKGAEILPNSQSPVPSPRLYKTGDLARYLPDGNIEYLGRIDNQIKIRGFRIEV 4223
Query: 315 QEVDHAVSTIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMI 494
E++ +S P V VV+ ++ + E + ++ L L YM+
Sbjct: 4224 GEIEAILSQHPGVRENVVVAREDIPGEKRLVVYFVPQLEQTPTTDDLRIFLKEKLPQYMV 4283
Query: 495 PQV-IEIETVPVLVNGKV 545
P + +E +P+ NGKV
Sbjct: 4284 PSAFVRLEFLPLTPNGKV 4301
>UniRef50_Q333U8 Cluster: NRPS protein; n=1; Micromonospora sp.
ML1|Rep: NRPS protein - Micromonospora sp. ML1
Length = 2594
Score = 108 bits (260), Expect = 7e-23
Identities = 62/177 (35%), Positives = 98/177 (55%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG PI+N V +LD +R V G G++ +AG LARGY R G RF+ NP P
Sbjct: 2315 IGTPIANTQVLILDSALRPVPPGVGGDLWIAGDGLARGYHRQPGLTASRFVANPFG--PQ 2372
Query: 204 FAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD + G I + GRAD Q+K+RG R++ +V+HA++ P V VV
Sbjct: 2373 GARMYRTGDLARWSESGRIEFLGRADFQIKLRGFRIEPGDVEHALTRHPAVREAVVTIRE 2432
Query: 381 VESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + ++ +V + +A + ++ + L DYM+P V+ + +P+ NGK+
Sbjct: 2433 DQPDDKRLVGYVVVAEDAETPPTRELQQFVREQLPDYMVPSAVVTLPAIPLTANGKL 2489
Score = 81.4 bits (192), Expect = 1e-14
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 5/158 (3%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
TVP+G PISN VY+LD ++ G GEV V G LARGY+ F+ P
Sbjct: 782 TVPLGRPISNAGVYVLDSQLQLTPPGVVGEVYVTGVGLARGYLHRPAATADHFVACPFG- 840
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD D G + +AG AD +V+IRG E++ ++ P VD V+
Sbjct: 841 -PAGTRMYRTGDLARWTDDGELEHAGSADQRVRIRGFWAAFLEIEAVLTAHPGVDQAAVI 899
Query: 372 CY--GVESSNPEILAFVTINPEARMSAKNIEAELTSSL 479
G + + +++A+V RM A ++ + ++ L
Sbjct: 900 ARPDGPDRA-AQLIAYVVPATGGRMGAAGLDVDFSAGL 936
>UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2419
Score = 108 bits (260), Expect = 7e-23
Identities = 62/180 (34%), Positives = 98/180 (54%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHN 191
+ VPIG +N+ +Y+LD +R V G GE+CVAG +L++GY+ +F+ NP
Sbjct: 2130 VNVPIGRVTANHQLYILDAQLRPVPIGVVGELCVAGPSLSQGYLNQPALSAEKFVPNPFA 2189
Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
P +LYRTGD L G+I + GR D QVK+RG+R++L E++ A+ P V VV
Sbjct: 2190 AQPG-QRLYRTGDVARYLPDGLIEHLGRIDHQVKVRGYRIELGEIEAALLNHPAVQEAVV 2248
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
L +S ++ +V + + L L YM+P + + +E++P NGK+
Sbjct: 2249 L----PTSEASLIGYVVLKQAGSTPTSELREFLQQRLPGYMLPAILVPLESLPRTANGKI 2304
Score = 93.1 bits (221), Expect = 4e-18
Identities = 51/146 (34%), Positives = 82/146 (56%), Gaps = 3/146 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VP+G PI+N+YVY+LD + V G GE+ + G +ARGY+ + RF+ + +T+
Sbjct: 749 VPLGRPIANSYVYVLDAARQLVPFGAIGELYIGGAGVARGYLNRPELTNERFVTDRLSTN 808
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+ +LYR+GD G++ + GR+D QVKIRG+RV+L E+ H + P V V
Sbjct: 809 PS-DRLYRSGDVVRYRPDGLLEFLGRSDDQVKIRGYRVELGEISHTLERHPLVQQSTVQL 867
Query: 375 YGVESSNPEILAFVTINPEARMSAKN 452
S +++ ++ NP + N
Sbjct: 868 REHASGEQQLVGYIVPNPALALPVSN 893
>UniRef50_A3IZW4 Cluster: Non-ribosomal peptide synthase; n=2;
Cyanothece sp. CCY 0110|Rep: Non-ribosomal peptide
synthase - Cyanothece sp. CCY 0110
Length = 1294
Score = 108 bits (260), Expect = 7e-23
Identities = 66/180 (36%), Positives = 101/180 (56%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++ IG PI+N +Y+LD N++ V G PGE+ + G LARGY+ D +FI NP T
Sbjct: 1036 SILIGRPINNTQIYILDPNLQPVPVGVPGELHIGGDGLARGYLNRPDLTAEKFIPNPFGT 1095
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
KLY+TGD + G I Y GR D QVKIRG R++L E++ +S P + VV+
Sbjct: 1096 ----GKLYKTGDLCRYRRDGNIEYIGRIDHQVKIRGFRIELGEIETQLSNHPEIRESVVI 1151
Query: 372 CYGVESSNPEILAFVTINPEARMS-AKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
N +++A++ + ++ S + + L L DYMIP + +E +P+ NGK+
Sbjct: 1152 AREDAPGNKQLVAYLVSDEMSQSSVTQTLRDCLKEQLPDYMIPSAFVLLEKLPLTPNGKI 1211
>UniRef50_A0PTU8 Cluster: Non-ribosomal peptide synthetase MbtE; n=1;
Mycobacterium ulcerans Agy99|Rep: Non-ribosomal peptide
synthetase MbtE - Mycobacterium ulcerans (strain Agy99)
Length = 1670
Score = 108 bits (260), Expect = 7e-23
Identities = 67/178 (37%), Positives = 103/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIGVP N Y Y+LDE + V + GE+ + G LARGY+ RFI +P N
Sbjct: 794 VPIGVPNRNVYAYVLDEQLHPVPDQVVGELYLGGSQLARGYLGRPTLTAQRFIADPFN-- 851
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +LYRTGD + G + + GRAD QVKIRG R++L EV+ ++T P V +C+V+
Sbjct: 852 PGM-RLYRTGDLVRRNHCGELEFVGRADEQVKIRGFRIELGEVESVITTHPAVRHCLVVA 910
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
E + P + A++ + A++ + I A +++ +YM+P I +P+ V+GK+
Sbjct: 911 EETE-AGPMLAAYL-VPAAAQVDLEEIRAHTAAAVPEYMVPGAFAVIPEIPMTVSGKL 966
>UniRef50_O30409 Cluster: Tyrocidine synthetase 3 (Tyrocidine
synthetase III) [Includes: ATP- dependent asparagine
adenylase (AsnA) (Asparagine activase); ATP- dependent
glutamine adenylase (GlnA) (Glutamine activase); ATP-
dependent tyrosine adenylase (TyrA) (Tyrosine activase);
ATP-dependent valine adenylase (ValA) (Valine activase);
ATP-dependent ornithine adenylase (OrnA) (Ornithine
activase); ATP-dependent leucine adenylase (LeuA)
(Leucine activase)]; n=8; cellular organisms|Rep:
Tyrocidine synthetase 3 (Tyrocidine synthetase III)
[Includes: ATP- dependent asparagine adenylase (AsnA)
(Asparagine activase); ATP- dependent glutamine adenylase
(GlnA) (Glutamine activase); ATP- dependent tyrosine
adenylase (TyrA) (Tyrosine activase); ATP-dependent
valine adenylase (ValA) (Valine activase); ATP-dependent
ornithine adenylase (OrnA) (Ornithine activase);
ATP-dependent leucine adenylase (LeuA) (Leucine
activase)] - Brevibacillus parabrevis
Length = 6486
Score = 108 bits (260), Expect = 7e-23
Identities = 66/185 (35%), Positives = 98/185 (52%), Gaps = 4/185 (2%)
Frame = +3
Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFI 176
+ H +PIG PI+N+ Y++D N + G PGE+CV G +ARGYV + +F+
Sbjct: 3876 EQHFEEQIPIGKPIANSTAYIVDGNNQPQPIGVPGELCVGGDGVARGYVNKPELTAEKFV 3935
Query: 177 HNPHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353
NP P +YRTGD L G I Y GR D QVKIRG+R++L E++ +S V
Sbjct: 3936 PNPF--APG-ETMYRTGDLARWLPDGTIEYLGRIDQQVKIRGYRIELGEIETVLSQQAQV 3992
Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVL 530
VV +E +N + PE + A + ++ L YM+P +++E +P+
Sbjct: 3993 KEAVVAV--IEEANGQKALCAYFVPEQAVDAAELREAMSKQLPGYMVPAYYVQMEKLPLT 4050
Query: 531 VNGKV 545
NGKV
Sbjct: 4051 ANGKV 4055
Score = 105 bits (253), Expect = 5e-22
Identities = 67/179 (37%), Positives = 97/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIGVP N +YLLD +M+ V G GE+ +AG +A+GY + +FI NP
Sbjct: 772 SVPIGVPADNVQLYLLDASMQPVPVGSLGEMYIAGDGVAKGYFNRPELTKEKFIDNPF-- 829
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P K+YRTGD L G + YAGR D QVKIRGHR+++ E++ ++ V VV+
Sbjct: 830 RPG-TKMYRTGDLAKWLPDGNMEYAGRMDYQVKIRGHRIEMGEIETRLTQHEAVKEAVVI 888
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
ES + A++ E ++ + L +L YMIP I + +P+ NGKV
Sbjct: 889 VEKDESGQNVLYAYLV--SERELTVAELREFLGRTLPSYMIPSFFIRLAEIPLTANGKV 945
Score = 100 bits (240), Expect = 2e-20
Identities = 60/178 (33%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+ IG P++N VY++DE G GE+C+ G LARGY+ + +F+ NP
Sbjct: 5969 ITIGRPLANVQVYIVDEQHHLQPIGVVGELCIGGAGLARGYLNKPELTAEKFVANPFR-- 6026
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++Y+TGD G I Y GRAD QVK+RG+R+++ E++ AV +D VV+
Sbjct: 6027 PG-ERMYKTGDLVKWRTDGTIEYIGRADEQVKVRGYRIEIGEIESAVLAYQGIDQAVVVA 6085
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+++ L + A +S + + L L YMIP +E++ +P+ NGKV
Sbjct: 6086 RDDDATAGSYLCAYFVAATA-VSVSGLRSHLAKELPAYMIPSYFVELDQLPLSANGKV 6142
Score = 95.1 bits (226), Expect = 9e-19
Identities = 61/181 (33%), Positives = 95/181 (52%), Gaps = 4/181 (2%)
Frame = +3
Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPH 188
+ +PIG PI N +Y+++ + + G GE+C+AG LARGY + ++ + F+ NP
Sbjct: 1807 YSAIPIGKPIDNVRLYVVNASNQLQPVGVAGELCIAGDGLARGYWQREELTKASFVDNPF 1866
Query: 189 NTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
P +YRTGD L G I Y GR D QVKIRGHR++L E++ + V V
Sbjct: 1867 --EPG-GTMYRTGDMVRYLPDGHIEYLGRIDHQVKIRGHRIELGEIEATLLQHEAVKAVV 1923
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542
V+ + A+V E + + L+++L YM+P + +E +P+ NGK
Sbjct: 1924 VMARQDGKGQNSLYAYVV--AEQDIQTAELRTYLSATLPAYMVPSAFVFLEQLPLSANGK 1981
Query: 543 V 545
V
Sbjct: 1982 V 1982
Score = 93.5 bits (222), Expect = 3e-18
Identities = 54/178 (30%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+ IG PI+N +Y++++ + G GE+C+ G LARGY +F+ +P
Sbjct: 2848 ITIGRPIANTSLYIVNQYHQLQPIGVVGEICIGGRGLARGYWNKPALTEEKFVSHPFAAG 2907
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++Y+TGD G L G I Y GR D QVK+RG+R+++ E++ A+ + VV+
Sbjct: 2908 E---RMYKTGDLGKWLPDGTIEYIGRIDEQVKVRGYRIEIGEIESALLAAEKLTAAVVVV 2964
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
Y + + A+ T + ++ + + L+ L YMIP ++++ +P+ NGKV
Sbjct: 2965 YEDQLGQSALAAYFT--ADEQLDVTKLWSHLSKRLPSYMIPAHFVQLDQLPLTPNGKV 3020
Score = 92.3 bits (219), Expect = 7e-18
Identities = 57/179 (31%), Positives = 92/179 (51%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVPIG P+ N +Y++D ++ G GE+C+ G +ARGY+ + +F+ NP
Sbjct: 4926 TVPIGKPLPNMTMYVVDAHLNLQPVGVVGELCIGGAGVARGYLNRPELTEEKFVPNPF-- 4983
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +LYRTGD G + + GR D QVKIRG R++L E++ + + + VV+
Sbjct: 4984 APG-ERLYRTGDLAKWRADGNVEFLGRNDHQVKIRGVRIELGEIETQLRKLDGITEAVVV 5042
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E+ A+V + ++ + A L L MIP + ++ +P+ NGKV
Sbjct: 5043 AREDRGQEKELCAYVV--ADHKLDTAELRANLLKELPQAMIPAYFVTLDALPLTANGKV 5099
>UniRef50_Q93H68 Cluster: Non-ribosomal peptide synthetase; n=1;
Streptomyces avermitilis|Rep: Non-ribosomal peptide
synthetase - Streptomyces avermitilis
Length = 1768
Score = 108 bits (259), Expect = 9e-23
Identities = 64/178 (35%), Positives = 102/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI N + +LD +R G PGE+C+AG LARGY+ + RF+ P
Sbjct: 589 VPIGRPIDNTRILVLDSGLRPQPVGVPGELCIAGVGLARGYLGRPELTAERFVAAP---A 645
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD L G I Y GR D QVK+RG+R++L E++ ++ P V + VVL
Sbjct: 646 AGEERVYRTGDLARWLPDGSIDYLGRIDHQVKVRGYRIELGEIEESLRRHPQVKDAVVLA 705
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E + +V + +A ++ ++++ L +L DYM+P +++ ++T P+ NGK+
Sbjct: 706 RKAEDGQTHLCGYVQ-SADA-LTEEDLKRHLGVTLPDYMVPARLVALDTFPLSPNGKL 761
>UniRef50_Q87WM7 Cluster: Non-ribosomal peptide synthetase, terminal
component; n=1; Pseudomonas syringae pv. tomato|Rep:
Non-ribosomal peptide synthetase, terminal component -
Pseudomonas syringae pv. tomato
Length = 3432
Score = 108 bits (259), Expect = 9e-23
Identities = 63/178 (35%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P++N Y+LDE ++ V G G + +AG L+RGY++ D RFI +PH T
Sbjct: 2902 VPIGRPVANTRTYILDETLQPVPIGVTGNLYLAGVQLSRGYLKRVDLTAERFIPDPHGT- 2960
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +++Y TGD G I Y GR D Q+K+RG R++L E++ + P V VV
Sbjct: 2961 PG-SRMYMTGDTARYRAHGEIEYLGRNDQQIKLRGFRIELGEIEMQLCAHPQVSQAVVSV 3019
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
++ NP + A++ N + + S + L +L DYM + ++ +P+ NGKV
Sbjct: 3020 NTSDADNPTLTAYLVCNADTQPSVDELRECLARTLPDYMADVCFQFLDHLPLTSNGKV 3077
Score = 106 bits (254), Expect = 4e-22
Identities = 60/177 (33%), Positives = 99/177 (55%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG P+ N+ +Y+LD ++ V G G++ +AG +LAR Y D RF+ NPH+ P
Sbjct: 1845 PIGKPLFNSQMYVLDASLEPVPVGVRGDLYIAGVHLARCYWERPDITAERFVPNPHSLSP 1904
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A++Y+TGD L G I Y GR+D QVKIRG R++L EV+ A+ V + +
Sbjct: 1905 G-ARMYKTGDVARYLPDGNIEYLGRSDHQVKIRGFRIELAEVEQALMAQETVASAAAMVR 1963
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+++ ++ + ++ +I+ L +L DYM+P + + T+P+ +GKV
Sbjct: 1964 EDRPGLKKLVGYLVAKSDCTLNIVDIKEHLRRTLPDYMVPTTFVILPTLPLTPSGKV 2020
Score = 100 bits (240), Expect = 2e-20
Identities = 56/176 (31%), Positives = 96/176 (54%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
+G PI+N + +LDEN R G PGE+ + G +ARGY+ D +F+ +P+ +
Sbjct: 787 LGRPIANTVLRVLDENARLCATGSPGELHIGGEGVARGYLDRADLTAQKFVPDPYASGSG 846
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++Y+TGD L G I + GR D QVK+RG R++L E++ + + P V V+
Sbjct: 847 -ARIYKTGDLVRWLPNGEIEFLGRIDHQVKVRGFRIELGEIETRLVSFPSVRQGAVIVRE 905
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + +I+A++ + + + + L +L YMIP + +E P+ NGK+
Sbjct: 906 DQPGDQQIVAYLLVGEQYAAEPEQLRHHLAQTLPGYMIPNHFVVLEQFPLTPNGKL 961
>UniRef50_Q5ZTI3 Cluster: Peptide synthetase, non-ribosomal; n=2;
Legionella pneumophila|Rep: Peptide synthetase,
non-ribosomal - Legionella pneumophila subsp. pneumophila
(strain Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 1453
Score = 108 bits (259), Expect = 9e-23
Identities = 58/159 (36%), Positives = 95/159 (59%), Gaps = 3/159 (1%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI N VY+LD M+ V G GE+ ++G LARGY+ + +F+ NP + + N
Sbjct: 915 IGKPIMNTKVYVLDAKMQPVPIGIMGELYISGDGLARGYLNNPEFTIQKFLPNPFSNNKN 974
Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LYRTGD + GV+ Y GR D+QVKIRG+R+++ E++ + IP + C+V
Sbjct: 975 -DRLYRTGDLVKWNSNGVLEYHGRCDNQVKIRGYRIEINEIESYLEKIPSIHQCIVKPEK 1033
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP 497
+ + + A++ + +++SA +I A L ++ +YMIP
Sbjct: 1034 NQDDSMSLSAYLVLEKNSQISAVDIRAILKQNIPEYMIP 1072
>UniRef50_A6E8C1 Cluster: Amino acid adenylation; n=1; Pedobacter sp.
BAL39|Rep: Amino acid adenylation - Pedobacter sp. BAL39
Length = 1329
Score = 108 bits (259), Expect = 9e-23
Identities = 61/180 (33%), Positives = 102/180 (56%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHN 191
+TVPIG P SN +Y++D++ G PGE+ + G LA+GY+ FI +P
Sbjct: 791 MTVPIGKPFSNTVIYVVDKHFNHCPVGVPGELYIGGRGLAKGYLGNPALTDQSFIKDPFA 850
Query: 192 THPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
T P AK+Y+TGD L G I Y GR D Q+KIRG+R++L E+ + + + V C V
Sbjct: 851 TTPE-AKIYKTGDLVRWLPDGNIQYMGRIDDQIKIRGNRIELGEIQNVLLSHADVLQCAV 909
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + + ++ A++ N + + + L SL +YMIP++ ++++ +P+ NGK+
Sbjct: 910 VVEENQGNEKQLAAYIVQN--GVLDKELMIQHLQKSLPEYMIPRMFLQLDQIPLTANGKI 967
>UniRef50_A3WXS1 Cluster: Probable non-ribosomal peptide synthetase;
n=2; Bradyrhizobiaceae|Rep: Probable non-ribosomal
peptide synthetase - Nitrobacter sp. Nb-311A
Length = 3272
Score = 108 bits (259), Expect = 9e-23
Identities = 58/180 (32%), Positives = 108/180 (60%), Gaps = 6/180 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNTH 197
VPIG+P++N V++LD ++ V G GE+ + G +ARGY G +F+ +P
Sbjct: 1453 VPIGLPLANLRVHVLDNSLNEVPIGVTGELYIGGAGVARGYRGAAGLTAEQFVPDPFGRA 1512
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ +LYRTGD D+ G +++ GR+D Q+K+RG+RV+ EV A+ +P +++ VV+
Sbjct: 1513 GD--RLYRTGDRVRCDRAGRLIFIGRSDDQIKLRGYRVEPDEVGRALKALPGINDAVVIA 1570
Query: 375 YGV--ESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++ E++A+ + A+ ++ +L++ + DYM+P +I +E +P+ NGK+
Sbjct: 1571 RSIDGQAGRQELVAYCVPGDGVTLEAEAVKRQLSAIVPDYMVPSHMIVLERLPLTSNGKI 1630
Score = 97.5 bits (232), Expect = 2e-19
Identities = 62/179 (34%), Positives = 94/179 (52%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
T PIG P+ Y+LD ++ V G GE+ + G LARGY+ RFI +P
Sbjct: 2986 TAPIGRPVGARTAYILDADLNVVPAGVTGELFIGGAGLARGYLNRSAMTAERFIPDPFGA 3045
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
N +LYRTGD D GVI Y GRAD QVKIRG R++L E++ + V V+
Sbjct: 3046 --NGDRLYRTGDLARWRDDGVIDYVGRADQQVKIRGFRIELGEIEACLIEQRGVRAAAVV 3103
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ ++A+ + +P + + L + L DYM+P ++ +E +P+ NGK+
Sbjct: 3104 AQDSKTGR-HLVAYASGDP--TLDGAALRDALAAVLPDYMVPATIVVLEQLPLSRNGKI 3159
Score = 46.8 bits (106), Expect = 3e-04
Identities = 38/147 (25%), Positives = 65/147 (44%), Gaps = 1/147 (0%)
Frame = +3
Query: 99 EPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAKLYRTGDFGILDKGVILYAGRAD 278
E GE+ V G ++ GY D R + + A+ RTGD G + G ++ AGR
Sbjct: 408 EVGEIWVTGPSVTLGYWNNPDATRQVF----VERDGARWLRTGDLGFIRDGALVVAGRLK 463
Query: 279 SQVKIRGHRVDLQEVDHAV-STIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNI 455
+ +RG + +V+ AV + + V V + VE+ E + A + ++
Sbjct: 464 DVLIVRGQNIYPTDVEQAVEADVESVRRGRVAAFAVEADGQEGIGVAAEFSRAVLKGEDP 523
Query: 456 EAELTSSLTDYMIPQVIEIETVPVLVN 536
E L ++ ++ Q E V VL+N
Sbjct: 524 EV-LAEAIGQAVLRQAQEYPAVIVLLN 549
>UniRef50_A0ZF81 Cluster: Amino acid adenylation protein; n=3;
Bacteria|Rep: Amino acid adenylation protein - Nodularia
spumigena CCY 9414
Length = 2558
Score = 108 bits (259), Expect = 9e-23
Identities = 61/174 (35%), Positives = 98/174 (56%), Gaps = 2/174 (1%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFA 209
IG PI+NN +Y+LD + + + G PGE+C+AG LARGY+ + +
Sbjct: 806 IGQPIANNSIYILDPHNQPLPPGIPGELCIAGVGLARGYLNRPETTSEKFMEIDLFGKVE 865
Query: 210 KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVE 386
++Y+TGD G + Y GR D QVK+RG R++L E++ + V VV+ Y +
Sbjct: 866 RIYKTGDLARWCADGNLEYLGRIDEQVKLRGFRIELGEIESLLLQHSLVKEAVVILYETD 925
Query: 387 SSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
SNP ++A+VT ++ I+ L + L +YMIP Q++ +E +P+ NGK+
Sbjct: 926 -SNPRLVAYVTQAEKSVTLGIEIKEYLKNRLPNYMIPSQIMVLEQLPLTANGKL 978
Score = 81.8 bits (193), Expect = 9e-15
Identities = 44/118 (37%), Positives = 68/118 (57%), Gaps = 3/118 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG P+SN +Y+LD + + + G PGE+C+AG LARGY+ + +FI
Sbjct: 1859 PIGKPLSNLRIYILDTDYQPLPPGIPGELCIAGVGLARGYLNRPELTAEKFIE--IELFG 1916
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
++Y+TGD L G + Y GR D QVK+RG R++L E++ ++ P + VV+
Sbjct: 1917 KVERIYKTGDLARWLPDGNLEYLGRIDHQVKLRGFRIELSEIEASLLKHPKIQEAVVI 1974
>UniRef50_P27206 Cluster: Surfactin synthetase subunit 1; n=15;
Bacillus|Rep: Surfactin synthetase subunit 1 - Bacillus
subtilis
Length = 3588
Score = 108 bits (259), Expect = 9e-23
Identities = 62/178 (34%), Positives = 93/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG + NN +Y+LD+ R EG GE+ +AG + RGY+ + +F+ +P
Sbjct: 777 VPIGKALGNNRLYILDQKGRLQPEGVAGELYIAGDGVGRGYLHLPELTEEKFLQDPFVPG 836
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD L G I Y GR D QVK+RG+R++L E++ + P V VVL
Sbjct: 837 D---RMYRTGDVVRWLPDGTIEYLGREDDQVKVRGYRIELGEIEAVIQQAPDVAKAVVLA 893
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545
E N E+ A+V P + + + L DYM+P E+ +P+ +GKV
Sbjct: 894 RPDEQGNLEVCAYVVQKPGSEFAPAGLREHAARQLPDYMVPAYFTEVTEIPLTPSGKV 951
Score = 106 bits (255), Expect = 3e-22
Identities = 67/178 (37%), Positives = 100/178 (56%), Gaps = 3/178 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194
++ IG I+N VY+L E + EG GE+CVAG LARGY+ +D RF+ +P
Sbjct: 2849 SLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAKRFVADPFV- 2907
Query: 195 HPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD G I Y GR D QVK+RG+R++L E++ ++ + V + V
Sbjct: 2908 -PG-ERMYRTGDLVKWTGGGIEYIGRIDQQVKVRGYRIELSEIEVQLAQLSEVQDAAVTA 2965
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ N I A+VT PE+ + +++ L +L DYMIP + + +PV NGKV
Sbjct: 2966 VKDKGGNTAIAAYVT--PES-ADIEALKSALKETLPDYMIPAFWVTLNELPVTANGKV 3020
Score = 99 bits (238), Expect = 3e-20
Identities = 60/180 (33%), Positives = 94/180 (52%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
L+VPIG P+SN VY+LD G GE+CV G L +GY + +F+ +P
Sbjct: 1814 LSVPIGKPVSNTEVYILDRTGHVQPAGIAGELCVTGEGLVKGYYNRPELTEEKFVPHPFT 1873
Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
+ ++Y+TGD L G I + GR D QVKIRG ++L E++H + T V VV
Sbjct: 1874 SG---ERMYKTGDLARWLPNGTIEFIGRIDHQVKIRGQAIELGEIEHQLQTHDRVQESVV 1930
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
L + + + A+ E +S++ + L YM+P V I+++ +P+ NGK+
Sbjct: 1931 LAVDQGAGDKLLCAYYV--GEGDISSQEMREHAAKDLPAYMVPAVFIQMDELPLTGNGKI 1988
>UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomonas
syringae pv. syringae|Rep: Amino acid adenylation -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 9498
Score = 107 bits (258), Expect = 1e-22
Identities = 57/176 (32%), Positives = 103/176 (58%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTHPN 203
IG P++N +YLLD + + V G GE+ + G +ARGY+ ++ + RF+ +P + P+
Sbjct: 3013 IGKPMANTRIYLLDAHQQPVPYGVAGEIYIGGDGVARGYLNLEEVNAERFLADPFSESPD 3072
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++Y+TGD + G I Y GR D QVK+RG R++L E++ + V VV+
Sbjct: 3073 -ARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCTGVKEAVVIARE 3131
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V P+++++A ++ AEL L +YM+P + ++ +P+ N K+
Sbjct: 3132 DNPGDKRLVAYVVAQPQSQLTAADLRAELAPQLAEYMLPSAFVLLDELPLTPNRKL 3187
Score = 106 bits (254), Expect = 4e-22
Identities = 57/176 (32%), Positives = 100/176 (56%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTHPN 203
IG P++N +YLLD + + V G GE+ + G +ARGY+ ++ + RF+ +P + P+
Sbjct: 4100 IGKPMANTRIYLLDAHQQPVPYGVAGEIYIGGDGVARGYLNLEEVNAERFLADPFSESPD 4159
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++Y+TGD + G I Y GR D QVK+RG R++L E++ + V VV+
Sbjct: 4160 -ARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCKGVKEAVVIARE 4218
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+V P+ +++A + AEL L +YM+P + ++ +P+ N K+
Sbjct: 4219 DNPGEKRLVAYVVAQPQTQITAAELRAELAPQLAEYMLPSAFVLLDELPLTPNRKL 4274
Score = 103 bits (247), Expect = 3e-21
Identities = 60/181 (33%), Positives = 100/181 (55%), Gaps = 5/181 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
L++PIG P +N VY+LD V G GE+ + G +A GY+ + RF +P +
Sbjct: 6218 LSLPIGKPNANVRVYVLDARREPVPMGVVGEIYIGGTGVALGYLNRPELTAERFSEDPFS 6277
Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
A+LYRTGD L G + Y R D QVK+RG RV+L E++ + V N VV
Sbjct: 6278 QQAG-ARLYRTGDLARWLPDGNLEYLARNDGQVKVRGFRVELGEIESVLHLCDGVRNSVV 6336
Query: 369 LCYGVESSNPEILAFVTINPEA-RMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542
+ + + ++A+ T++ +++ A+L++ L +YM+P V + ++ +P+ +NGK
Sbjct: 6337 VAHEASPGDTRLVAYYTVHAGVDAPDPEDLRAQLSADLAEYMVPSVFVRLDALPLTLNGK 6396
Query: 543 V 545
V
Sbjct: 6397 V 6397
Score = 103 bits (246), Expect = 4e-21
Identities = 62/180 (34%), Positives = 102/180 (56%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PI+N +++LD + G GE+ + G +ARGY+ D RFI +P ++
Sbjct: 832 SVPIGRPIANIQMHVLDTLGQLQPLGVAGELHIGGIGVARGYLNQPDLSAERFIADPFSS 891
Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LY+TGD G L G + Y GR D QVKIRG R+++ E++ A++ P V VV
Sbjct: 892 DPQ-ARLYKTGDVGRWLANGALEYLGRNDFQVKIRGLRIEIGEIEAALAKHPAVHEAVVT 950
Query: 372 CYGVESSNPEILAFVTINPE-ARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ T + E + + + + L L +YM+P + + +E +P+ NGK+
Sbjct: 951 AREDIPGDKRLVAYYTQSAEHTAVDLEILRSHLQQQLPEYMVPAIYVLLEAMPLTSNGKL 1010
Score = 99 bits (238), Expect = 3e-20
Identities = 56/176 (31%), Positives = 97/176 (55%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+N V++LD G GE+ + G +ARGY+ + RFI +P + N
Sbjct: 8383 IGRPIANVQVHVLDARGEPAPLGVAGEIHIGGSGVARGYLNRDELSAERFIVDPFSDVAN 8442
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LY+TGD G L G + Y GR D QVK+RG R++L E+++ + +P + +V+
Sbjct: 8443 -ARLYKTGDLGRWLADGTLEYMGRNDFQVKVRGFRIELGEIENVLLAVPGIREAIVIARN 8501
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + V ++A+++ +EL L +YM+P ++++ +P+ NGK+
Sbjct: 8502 DSQGDSDSQRLVAYVCGESVAAEHLRSELLRHLPEYMVPSAFVQLDALPLTANGKL 8557
Score = 98.7 bits (235), Expect = 8e-20
Identities = 61/180 (33%), Positives = 100/180 (55%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PI+N +++LD + G GE+ + G +ARGY+ D RFI +P +
Sbjct: 1922 SVPIGRPIANIQMHVLDALGQLQPLGVAGELHIGGIGVARGYLNQPDLSAERFIADPFSE 1981
Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A+LY+TGD G L G + Y GR D QVKIRG R+++ E++ A++ P V VV
Sbjct: 1982 DRQ-ARLYKTGDVGRWLANGALEYLGRNDFQVKIRGLRIEIGEIEAALAKHPAVHEAVVT 2040
Query: 372 CYGVESSNPEILAFVTINPE-ARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ T + E + + + + L L +YM+P + + +E +P+ NGK+
Sbjct: 2041 AREDIPGDKRLVAYYTQSAEHTAVDLEILRSHLQQQLPEYMVPAIYVLLEAMPLTSNGKL 2100
Score = 88.6 bits (210), Expect = 8e-17
Identities = 53/176 (30%), Positives = 93/176 (52%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG + + + +LD+ + V G GE+ + G +AR Y+ + RFI +P+
Sbjct: 7295 IGPALDDLCLRILDDYQQPVPVGVNGEIYIGGAGVARHYLNRTELNAERFIADPYALQSG 7354
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LYRTGD G ++Y GR DSQ+KIRG R++L E++ + P V +V+
Sbjct: 7355 -ARLYRTGDVAHYRSDGGVVYVGRNDSQIKIRGFRIELGEIEAQLLACPDVREAMVIVRE 7413
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A++ A + + ++L S L ++M+P + +ET P+ NGK+
Sbjct: 7414 DRPGDKRLVAYLIAEDGAAPESALLRSQLASVLAEHMLPSAFVTLETWPLTTNGKL 7469
Score = 82.6 bits (195), Expect = 5e-15
Identities = 55/183 (30%), Positives = 96/183 (52%), Gaps = 9/183 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG ++N +YLLDE + V G GE+ + G +ARGY+ + RF+ NP
Sbjct: 5162 LPIGRALANTRIYLLDELGQAVPPGVAGELYIGGAGIARGYLNLQQLTAERFMDNPFVAG 5221
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYR+GD G I + GR DSQ K+RG R++L E++ ++ + V +V+
Sbjct: 5222 ---ERLYRSGDMARYRADGNIEFLGRNDSQAKLRGLRLELGEIEARLAEVAGVRESLVVI 5278
Query: 375 YGVESSNPEILAF---VTINPEA--RMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536
P+++A+ E+ ++ + + +L +L +YMIP + + +P+ N
Sbjct: 5279 REDSGGTPKLIAYFVEYATRDESGPALTPRALRQQLQLNLPEYMIPAAFVRMAALPLSAN 5338
Query: 537 GKV 545
GK+
Sbjct: 5339 GKL 5341
>UniRef50_Q1D3K4 Cluster: Non-ribosomal peptide synthase; n=2;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 3292
Score = 107 bits (258), Expect = 1e-22
Identities = 66/179 (36%), Positives = 98/179 (54%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197
VPIG P+ Y+LD + V G GE+ + G LARGY R RF+ +PH T
Sbjct: 1471 VPIGQPLRTMGAYVLDGRLEPVPAGGVGELWLTGEGLARGYFRDPALTAERFMADPHATT 1530
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +++YRTGD + GV+ Y GRAD QVK+RG RV+L E++ A+ V + +VL
Sbjct: 1531 PG-SRIYRTGDLARMRADGVLEYLGRADDQVKVRGFRVELGEIETALRACEGVRDAIVLL 1589
Query: 375 YGVES-SNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+G + ++A+ PE SA + A+L + L YM+P ++ + P +GKV
Sbjct: 1590 HGENAGKEARLIAYAVAAPEVAPSA--LRAQLAARLPPYMVPAAIVRLAAFPYGSSGKV 1646
Score = 103 bits (248), Expect = 2e-21
Identities = 61/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P++ V+LLD + V G PGE+ AG LARGY+ D RF+ +P +
Sbjct: 2526 VPIGAPVTGTRVHLLDAGLEPVPLGAPGELYCAGDGLARGYMGHADLTAERFLPDPFSRK 2585
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +++YRTGD G I + GR D+QVK+RG R++ EV+ + P V + V+
Sbjct: 2586 PG-SRMYRTGDLACWRADGSIEFLGRVDNQVKVRGFRIEPGEVEATLLRHPAVRDAAVVA 2644
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
G + ++A V + + +++ ++ L L ++MIP V+ +P+ NGKV
Sbjct: 2645 AGERADTKRLVAHVVLRDASAITSGDLRDYLEPQLPEHMIPSAVVFHHALPLSPNGKV 2702
Score = 42.7 bits (96), Expect = 0.005
Identities = 33/116 (28%), Positives = 46/116 (39%), Gaps = 1/116 (0%)
Frame = +3
Query: 72 ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAKLYRTGDFGILDKG 251
E R+GE GE+ V+G ++A GY + RTGD G L G
Sbjct: 391 ETFELRRDGEIGEIWVSGSSVAGGYWGQPEATTRTFQARLRGTGEGPFLRTGDLGFLRDG 450
Query: 252 VILYAGRADSQVKIRGHRVDLQEVDHAVSTI-PCVDNCVVLCYGVESSNPEILAFV 416
+ GRA + IRG Q+++ V P V + VE+ E L V
Sbjct: 451 ELFVTGRAKDLIIIRGLNHFPQDIEFTVEKCHPAVRPGSGAAFSVEADGTEQLVVV 506
>UniRef50_Q0RMQ5 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Frankia alni ACN14a|Rep: Putative non-ribosomal
peptide synthetase - Frankia alni (strain ACN14a)
Length = 2623
Score = 107 bits (258), Expect = 1e-22
Identities = 67/181 (37%), Positives = 100/181 (55%), Gaps = 7/181 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIGVPI N VY+LD +R V G PGE+ +AG LARGY+ G RF+ P
Sbjct: 2338 VPIGVPIWNMRVYVLDAGLRPVPPGVPGELYLAGVGLARGYLGQVGLTAGRFVACPFGGV 2397
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD + G + Y GR+D QVK+RG R++L E++ A+++ P + V +
Sbjct: 2398 GE--RMYRTGDVVRWNSAGQVEYLGRSDFQVKVRGFRIELGEIEQALTSQPGIGGAVAIV 2455
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEA---ELTSSLTDYMIPQVI-EIETVPVLVNGK 542
++ N ++A+V +A + +IE L L +YM+P VI + P +GK
Sbjct: 2456 REDQAGNQRLVAYVVAEDQASVGQPDIEEVTDRLRRQLPEYMVPSVIVPLTEFPTTPSGK 2515
Query: 543 V 545
V
Sbjct: 2516 V 2516
Score = 72.1 bits (169), Expect = 8e-12
Identities = 59/194 (30%), Positives = 87/194 (44%), Gaps = 21/194 (10%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNTHP 200
PIG P+ N Y+L + V G GE+ VAG L RGY G RF+ NP HP
Sbjct: 806 PIGTPLGNMRAYVLGPGLAPVPPGVVGELYVAGRCLGRGYHGQPGLTAVRFVANPW-CHP 864
Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD D G + GR D QVK+RG R++ EV+ + VV+
Sbjct: 865 G-ERMYRTGDLARRDADGRLECVGRGDGQVKVRGFRIETAEVEAVCELHLGISRAVVVGR 923
Query: 378 GVESSNPEILAFVT-----------------INPEARMSAKNIEAELTSSLTDYMIPQV- 503
S ++A+V ++ ++ SA + L + L DYM+P
Sbjct: 924 EAPSGGRRLVAYVVHTGEGAVGDDGAGGIGDVDMQSGASAAELRRFLAARLPDYMVPSAF 983
Query: 504 IEIETVPVLVNGKV 545
+ + +P GK+
Sbjct: 984 VVVGELPYGPTGKL 997
>UniRef50_A5IDB4 Cluster: Peptide synthetase; n=4; Legionella
pneumophila|Rep: Peptide synthetase - Legionella
pneumophila (strain Corby)
Length = 507
Score = 107 bits (258), Expect = 1e-22
Identities = 64/182 (35%), Positives = 104/182 (57%), Gaps = 5/182 (2%)
Frame = +3
Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPH 188
F TVPIG PI N ++LDE + EPGE+ ++G LA+GY+ FI NP+
Sbjct: 321 FDTVPIGKPIQNTQFFVLDEQLNSTGF-EPGELYISGVGLAQGYLNNPVLTQASFIDNPY 379
Query: 189 NTHPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
P K+YRTGD ++ G +L+ GR D QVK+RG R++L E+ H + P + + V
Sbjct: 380 L--PG-EKMYRTGDIVRWNQEGELLFLGRKDDQVKLRGIRIELGEIQHHLLAHPNIHDAV 436
Query: 366 VLCYGVESSNPEILAF-VTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNG 539
V+C V+ + ++ F + N + ++ + +++ L + L DYMIP+ + + P+ NG
Sbjct: 437 VVCEKVDCLDHRMVVFLIANNKQTKIGSAELKSFLKNRLPDYMIPEHYLWLSAFPIKENG 496
Query: 540 KV 545
K+
Sbjct: 497 KI 498
>UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5;
root|Rep: Amino acid adenylation domain - Clostridium
cellulolyticum H10
Length = 3235
Score = 107 bits (258), Expect = 1e-22
Identities = 62/178 (34%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V IG PI+N VY+LD M+ G PGE+ + G LARGY++ + +FI NP ++
Sbjct: 1436 VSIGKPIANTTVYVLDNEMKPTPVGIPGELYIGGTGLARGYLKLPELTQEKFIPNPFSSE 1495
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++LY+TGD + G I + GR D QVKIRG R++L E++ ++ P + VV+C
Sbjct: 1496 EG-SRLYKTGDIVRFMPDGNIEFIGRGDHQVKIRGFRIELGEIETLLNKNPLISQSVVVC 1554
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+V I +A L + L DYMIP + +++ P+ N K+
Sbjct: 1555 REISLGEKALIAYV-IPKSQETAATTFREYLRNRLPDYMIPSYFVILDSFPMTPNNKI 1611
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 5/176 (2%)
Frame = +3
Query: 33 GVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAK 212
G PI + YV + D + + E + G +C++G N+ GY K+ R
Sbjct: 374 GYPIYDCYVRICDIDNNDIGENKIGYICISGANVTSGYYNNKEATRKAITKDG------- 426
Query: 213 LYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGV--- 383
TGD G + G ++ GRA + ++G +++ + +D ++ G
Sbjct: 427 WLNTGDLGFMRDGRLVITGRAKDVIFVKGQNYYSHDIERVAQEVDGIDVGKIVAVGAFNE 486
Query: 384 ESSNPEILAFVTINPEARMSAKNIEA--ELTSSLTDYMIPQVIEIETVPVLVNGKV 545
+ + E++ FV + + + +L S + QVI I+++P +GKV
Sbjct: 487 KIKSDELILFVLFKMKVDKFIGLVRSLKKLISERMGIEVSQVIPIKSIPKTTSGKV 542
>UniRef50_Q5JCL8 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Pseudomonas fluorescens|Rep: Putative non-ribosomal
peptide synthetase - Pseudomonas fluorescens
Length = 1432
Score = 107 bits (257), Expect = 2e-22
Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
+PIG PI N Y++D N+ V G PGE+ +AG NLARGY+ + RF+ NP
Sbjct: 752 IPIGYPIDNTDAYIVDLNLNPVPPGVPGEIMLAGQNLARGYLGKPAQTAQRFLPNPFGN- 810
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++Y TGD G G I Y GR D QVKIRGHR++L EV H + + +V
Sbjct: 811 ---GRVYATGDLGRRWSSGAISYLGRRDQQVKIRGHRIELNEVAHLLCQALELKEAIVFA 867
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A I + + ++ I+ EL L Y+IP Q++ ++ +P GKV
Sbjct: 868 QHAGTEQARLVA--AIEQQPGLHSEGIKQELLRHLPAYLIPSQLLLLDELPRTATGKV 923
>UniRef50_Q1D3K7 Cluster: Non-ribosomal peptide synthase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 1515
Score = 107 bits (257), Expect = 2e-22
Identities = 64/179 (35%), Positives = 101/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+P+ PI N VY+LD +R V G GE+ V G LARGY+ D F+ NP +T
Sbjct: 773 TLPLERPIDNTQVYVLDARLRPVAVGMTGELYVGGAALARGYLNRPDLTAQSFLPNPFST 832
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A++YRTGD L G + + GRAD+QVK G+R++L E+ HA++ P V + V++
Sbjct: 833 TPG-ARMYRTGDLARHLPDGTLEHLGRADNQVKYHGYRIELNELRHALNQHPQVRDSVMM 891
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ N ++A+ E + + A L L + ++P V + ++ +P+ +NGKV
Sbjct: 892 LKRDTNGNEVLVAYYVSRQEQEHA--QLRAFLAERLIEEVLPNVYVHLKKLPLTLNGKV 948
>UniRef50_Q08XI8 Cluster: Beta-lactamase, putative; n=3; Bacteria|Rep:
Beta-lactamase, putative - Stigmatella aurantiaca DW4/3-1
Length = 3136
Score = 107 bits (257), Expect = 2e-22
Identities = 60/176 (34%), Positives = 93/176 (52%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PIS Y+LD + V G PGE+ ++G LARGY+ + RF+ NP +T P
Sbjct: 1511 IGRPISGTRAYVLDRQLHLVPRGVPGELYLSGSGLARGYINRPELTAERFLPNPFSTEPG 1570
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++LY+TGD G + Y GR D QVKIRG R++L E++ + T P + VL +
Sbjct: 1571 -SRLYKTGDLARFAVDGNLEYLGRIDHQVKIRGFRIELGEIESILLTQPGLHQAAVLAHE 1629
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V + + L L DYM+P + ++ +P+ NGK+
Sbjct: 1630 EAPGDKRLVAYVVAARNHSFTPAELRRLLKERLPDYMVPSAFVLLDALPLTPNGKL 1685
Score = 33.5 bits (73), Expect = 3.3
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 2/103 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLD--ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTH 197
V G + N + ++D ++ C G+ GE+ V G ++A+GY + I
Sbjct: 412 VGCGQTVPNQEILIVDPVSSVPCP-PGKVGEIWVCGPSVAQGYWQKPTETGQIFQARPAS 470
Query: 198 PNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVD 326
RTGD G L + + GR + IRG Q+++
Sbjct: 471 GGERVYLRTGDLGFLKERELFVTGRQKDLIIIRGRNHFPQDLE 513
>UniRef50_A4PHM3 Cluster: Hybrid non ribosomal peptide
synthetase-polyketide synthase; n=2; cellular
organisms|Rep: Hybrid non ribosomal peptide
synthetase-polyketide synthase - Streptomyces virginiae
Length = 2589
Score = 107 bits (257), Expect = 2e-22
Identities = 64/182 (35%), Positives = 101/182 (55%), Gaps = 7/182 (3%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHN 191
TVPIG PI+ ++++DE M V +G PGE+ + G +A GY G+ RF+ +P
Sbjct: 1225 TVPIGRPIARTRIHVVDERMARVPDGTPGEIVIGGAGVALGY-HGRPELTAERFVASPFA 1283
Query: 192 THPNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
P+ +LYRTGD G L G I Y GR D Q K+RG R++ +EV+ A++ +P V V
Sbjct: 1284 DDPS-PRLYRTGDLGQLGPDGEIRYLGRIDGQFKLRGLRIEPEEVEAALTELPGVSEARV 1342
Query: 369 LCYGVESSNPEILAFVTINPEARM--SAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNG 539
L ++ +ILA V + + + S + +L SL Y++P ++ +P+ NG
Sbjct: 1343 LPVTDPATGEQILAAVCVEADGTLAPSVGQMRRDLARSLPSYLVPSSFRFVDRLPLTANG 1402
Query: 540 KV 545
K+
Sbjct: 1403 KL 1404
>UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 4196
Score = 107 bits (257), Expect = 2e-22
Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG PI N +Y+LD+N + V +G GE+C+ G L RGY G RFI +
Sbjct: 1622 VPIGKPIDNVQIYILDKNQKLVPQGMVGELCIGGIGLTRGYYNDPGLTKERFIECEGISG 1681
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
K+YRTGD +G I + GR D+QVKIRG+R+++ E++ ++ + P + V +
Sbjct: 1682 ---RKVYRTGDLAKWTQEGNIEFLGRVDNQVKIRGYRIEMGEIEASILSHPAIREAVAIA 1738
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ I A++ + +S + L SL YMIP + ++IE +P+ NGK+
Sbjct: 1739 KEDSTGGKYICAYIV--SDTGLSITELRDYLQKSLPGYMIPSRFVQIEKMPLTPNGKI 1794
Score = 105 bits (251), Expect = 9e-22
Identities = 62/178 (34%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG P+ N VY+L EN + G GEV ++G + GY+ + RFI NP N
Sbjct: 579 IPIGKPMPNVQVYILGENQELIPRGCIGEVYISGTGVGVGYLSREQMTSERFIPNPFNVD 638
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
K+Y+TGD G L G I + GR D QVKIRG+R++L E++ + + VV
Sbjct: 639 K---KMYKTGDLGRWLPDGNIEFIGRKDGQVKIRGYRIELGEIEAQLQKHENIREAVVTD 695
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+S N + A+ T N ++ + L+ + +YMIP ++IE +P+ +NGK+
Sbjct: 696 RKEDSENKVLCAYFTAN--EKLGVTQLREHLSDKIPEYMIPTYFVQIEKMPLTINGKL 751
Score = 99 bits (238), Expect = 3e-20
Identities = 58/177 (32%), Positives = 99/177 (55%), Gaps = 3/177 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
V IG PI+N + +++ +N++ + G GEVC+ G +LARGY+ + + P
Sbjct: 3727 VSIGGPIANTQILIMNGDNLQPI--GVAGEVCIGGDSLARGYLNRSELTKEKFVSSELVP 3784
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+LY+TGD + G I + GR D+QVKIRG+R++L E++ + ++ CVV+
Sbjct: 3785 G-KRLYKTGDLAKWMPDGSIAFMGRIDNQVKIRGYRIELDEIEKCILKYNLINECVVIAQ 3843
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E SN +++ + + E +S I + L DYMIP + + + ++P+ NGKV
Sbjct: 3844 EDEFSNKQLICYYVSSEEITVS--EIMQHIGRDLPDYMIPGIYVRLASIPLTPNGKV 3898
Score = 86.2 bits (204), Expect = 4e-16
Identities = 55/179 (30%), Positives = 88/179 (49%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNT 194
TVPIG + + LL+++ + E GE+ L++GY + K H+F NP
Sbjct: 2681 TVPIGYELEGVSIQLLNDDNKAAGIYECGELVYHSHYLSQGYWNLDEKTNHQFERNPETG 2740
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
Y++GD +L G I + GR D+QVKIRG R++L E++ V + + C +
Sbjct: 2741 E---VIAYKSGDLARLLPSGTIEHLGRKDTQVKIRGMRIELTEIESVVGGLKGIRECAAI 2797
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545
+ I+ F E + K + L S L +YMIP ++ +E++P NGKV
Sbjct: 2798 VLEKPNQENTIVVFYVPENEEVIENKQFKLMLKSKLPEYMIPSLLYPVESIPHTPNGKV 2856
>UniRef50_Q881Q3 Cluster: Non-ribosomal peptide synthetase, terminal
component; n=5; cellular organisms|Rep: Non-ribosomal
peptide synthetase, terminal component - Pseudomonas
syringae pv. tomato
Length = 5929
Score = 107 bits (256), Expect = 2e-22
Identities = 64/180 (35%), Positives = 98/180 (54%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PI N VY+L+ R G GE+ + G +A GY+ + +FI +P +
Sbjct: 2977 SVPIGRPIGNTRVYVLNAQQRLAPLGVIGELYIGGDGVALGYLNRPELTVEKFIADPFSD 3036
Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A +YRTGD G L+ G + GR D QVKIRG R++L E+ + + +P + VVL
Sbjct: 3037 QPG-AMMYRTGDLGRWLEDGQLECLGRNDDQVKIRGFRIELGEIVNCLHQLPGIREAVVL 3095
Query: 372 CYGVESSNPEILAFVTINPEARMSAK-NIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E N ++A+ T + A + A + ++L DYM+P IE+ +P+ NGK+
Sbjct: 3096 AREDEPGNVRLVAYFTSQQDVEAPAPGQMRAHMQANLPDYMVPVAFIELTALPLTANGKL 3155
Score = 105 bits (253), Expect = 5e-22
Identities = 61/180 (33%), Positives = 100/180 (55%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++ IG PI+N VYLLD + V G GE+ + G ++ARGY+ RF+ +P
Sbjct: 852 SLDIGKPIANTSVYLLDSLHKLVPFGVAGELYIGGESVARGYLNQPQLTAERFLRDPFAE 911
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A++YRTGD + G + Y GR D QVK+RG R++L E++ S +P ++ +VL
Sbjct: 912 PPQ-ARMYRTGDLARWNPDGTLEYLGRNDDQVKLRGVRIELGEIESQFSQLPGIEEALVL 970
Query: 372 CYGVESSNPEILAFVTINPEARMS-AKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E P ++ + T +A S +++ L + L YM+P ++ +++ P+ NGKV
Sbjct: 971 AREDEPGQPRLVGYFTERADATPSRLEDLRTALAARLPAYMVPGALVRLDSWPLTANGKV 1030
Score = 105 bits (253), Expect = 5e-22
Identities = 60/180 (33%), Positives = 101/180 (56%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++ IG PI+N VYLLDE + V G GE+ + G +ARGY+ RF+ +P
Sbjct: 4021 SLDIGKPIANTRVYLLDEQQQLVPLGVAGELYIGGEGVARGYLNQPQLTAERFLLDPFAG 4080
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P+ A++YRTGD + G + Y GR D QVKIRG R++L E++ ++ +P ++ +V+
Sbjct: 4081 QPH-ARMYRTGDLARWNADGTLDYLGRNDDQVKIRGVRIELGEIEAQLAQLPGIEEALVM 4139
Query: 372 CYGVESSNPEILA-FVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E ++A F+ A ++A + +++ + L YM+P + ++ P+ NGKV
Sbjct: 4140 AREDEPDQSRLVAYFIERADSATVAAAQLRSDMLARLPGYMVPSAFVRLDAWPLTANGKV 4199
Score = 103 bits (248), Expect = 2e-21
Identities = 60/176 (34%), Positives = 100/176 (56%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+++ +Y+LD + + V G PGE+ + G +ARGY+ D RF+ +P + +
Sbjct: 5083 IGKPVAHARLYVLDAHSQPVPLGVPGELYIGGTGVARGYLNRPDLTAERFLDDPFS-NVT 5141
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD L G + Y GR D QVKIRG RV+L E++ ++ P V VV
Sbjct: 5142 AARMYRTGDLVRWLADGTLEYLGRNDDQVKIRGVRVELGEIEQQLAQCPGVAEAVVTTQR 5201
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+E ++A+ T +A + + + ++L L +YM+P + ++ +P+ NGKV
Sbjct: 5202 LEDGTLRLVAYFT-RRDAALDSATLRSQLLGRLPEYMVPATYVGLDALPLTQNGKV 5256
Score = 89.8 bits (213), Expect = 4e-17
Identities = 58/178 (32%), Positives = 94/178 (52%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200
PIG I++ +Y+LD V G GE+ V G +ARGY+ + RF+ NP + H
Sbjct: 1914 PIGKRIADLQLYVLDTCGEPVPLGVVGELYVGGAGVARGYLNREALTAERFLDNPFS-HA 1972
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A++YRTGD + G + Y GR D QVKIRG R++L E+ ++ P V + VV+
Sbjct: 1973 ADARIYRTGDLARWMADGSLEYLGRNDEQVKIRGFRIELGEIASRLNDHPQVLDAVVVAR 2032
Query: 378 GVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++ + T + + + + A L+ L DYM+P + + +P+ NGK+
Sbjct: 2033 EDVPGDKRLVGYYTCAEDQTGLDIEQLRAWLSGLLPDYMVPAAFVRLAGLPITANGKL 2090
>UniRef50_Q2Y7Z5 Cluster: Amino acid adenylation; n=2; Nitrosospira
multiformis ATCC 25196|Rep: Amino acid adenylation -
Nitrosospira multiformis (strain ATCC 25196 / NCIMB
11849)
Length = 4037
Score = 107 bits (256), Expect = 2e-22
Identities = 68/184 (36%), Positives = 102/184 (55%), Gaps = 9/184 (4%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
+VPIG PIS Y+LD ++ V +G GE+ + G LARGY+ G RFI +P +
Sbjct: 2365 SVPIGKPISGLQAYILDVHLNQVPQGVAGELYLGGIGLARGYLNRGGLTADRFIADPFD- 2423
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LYRTGD G I Y GR D QVKIRG R++L E++ + P V VV+
Sbjct: 2424 -ETGGRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIETQLLAQPEVREAVVV 2482
Query: 372 C-YGVESSNP----EILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLV 533
G +SNP ++A+V+ + + A + L +L DYM+P ++ +E++P+
Sbjct: 2483 AREGSNASNPTGGARLIAYVSAHATTDLDAARLREALARTLPDYMLPSMIVVLESLPLNP 2542
Query: 534 NGKV 545
+GKV
Sbjct: 2543 SGKV 2546
Score = 105 bits (251), Expect = 9e-22
Identities = 65/183 (35%), Positives = 100/183 (54%), Gaps = 9/183 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+PIG P+ + Y+LD ++ V G GE+ + G LARGY+ G RFI +P +
Sbjct: 831 MPIGCPVGDRIAYILDSDLNPVPAGVAGELYLGGIGLARGYLNRGGLTADRFIADPFD-- 888
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD G I Y GR D QVKIRG R++L E++ + P V VV+
Sbjct: 889 ETGGRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIETQLLAQPEVREAVVVA 948
Query: 375 -YGVESSNP----EILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVN 536
G +SNP ++A+V+ + + A + L +L DYM+P ++ +E++P+ +
Sbjct: 949 REGSSASNPTGGARLIAYVSAHATTDLDAARLREALARTLPDYMLPSMIVVLESLPLNPS 1008
Query: 537 GKV 545
GKV
Sbjct: 1009 GKV 1011
Score = 96.3 bits (229), Expect = 4e-19
Identities = 66/188 (35%), Positives = 103/188 (54%), Gaps = 15/188 (7%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHP 200
PIG P+ Y+LD +M+ V G GE+ + G+ LARGY+ G RF+ +P +
Sbjct: 3449 PIGRPVGERTAYVLDLDMQPVPIGRVGELYIGGYGLARGYLGRAGLTAERFVADPFD--G 3506
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP-CVDNCVVLC 374
N +LYRTGD LD G I Y GRAD QVKIRG R++L E++ + + D VV+
Sbjct: 3507 NGGRLYRTGDLVRWLDDGNIEYIGRADHQVKIRGFRIELGEIEACIRELTGLTDVAVVVR 3566
Query: 375 YGVESSNPEILAFVT-------INPEARMSA---KNIEAELTSSLTDYMIP-QVIEIETV 521
G + P++ A+V + P + SA ++ +L L +YM+P ++ ++ +
Sbjct: 3567 EG--AGGPQLAAYVAPKETTGMVAPVRKGSAGLGSTLKQQLVRRLPEYMVPAHIVILDKL 3624
Query: 522 PVLVNGKV 545
P L +GK+
Sbjct: 3625 PRLPSGKL 3632
>UniRef50_Q50857 Cluster: Saframycin Mx1 synthetase B; n=1; Myxococcus
xanthus|Rep: Saframycin Mx1 synthetase B - Myxococcus
xanthus
Length = 1770
Score = 107 bits (256), Expect = 2e-22
Identities = 62/178 (34%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGK-DPHRFIHNPHNTH 197
V IG P++N VY+LD ++ V G GE+ + G +ARGY+ R + RF+ +P
Sbjct: 1479 VSIGRPVANTQVYVLDRHLAPVPVGVRGELFIGGAGVARGYLGRPRMTAERFLPDPFREA 1538
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YRTGD +G + + GRAD QVK+RG R++ +E++ A+ P V VV+
Sbjct: 1539 PG-ARMYRTGDIVRYRAEGSLEFLGRADHQVKVRGFRIEFEEIETALRNHPAVREAVVVA 1597
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
G + ++A+V ++ + L L DYM+P V + +E +P+ NGKV
Sbjct: 1598 RGT-GAERHLVAYVVLSARGESLVTELREHLRGRLPDYMVPGVFVMMEVLPLTPNGKV 1654
Score = 37.5 bits (83), Expect = 0.20
Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMR-CVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
V G + + + ++D R + G GE+ V G ++A+GY +
Sbjct: 390 VSCGTVVPDEQILVVDPETRTALPPGHIGEIWVRGPSVAQGYWLRPEETARTFQARLAGG 449
Query: 201 NFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV 335
A RTGD G L G + +GR + IRG Q+++ V
Sbjct: 450 TEAPWLRTGDLGFLHDGELFVSGRRKDLLVIRGRNYYPQDLELTV 494
>UniRef50_A4C379 Cluster: Non-ribosomal peptide synthetase, terminal
component; n=1; Pseudoalteromonas tunicata D2|Rep:
Non-ribosomal peptide synthetase, terminal component -
Pseudoalteromonas tunicata D2
Length = 3345
Score = 107 bits (256), Expect = 2e-22
Identities = 65/185 (35%), Positives = 105/185 (56%), Gaps = 10/185 (5%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-- 188
+VPIG PI N +Y+LD+ + + +G GE+ + G LARGY+ + RFI NP
Sbjct: 3045 SVPIGKPIQNIQLYILDDELNLLPQGACGELHIGGDGLARGYLNRPELTQERFIANPFYQ 3104
Query: 189 -NTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
+ +LY+TGD + G I Y GR D QVKIRG R++L E+++ V+ +D+
Sbjct: 3105 AEEGNSSERLYKTGDLVRYKEDGNIEYMGRLDHQVKIRGFRIELGEIEYQVAQHKQIDSA 3164
Query: 363 VVLCYGVESSNPEILAF-VTINPEARMS--AKNIEAELTSSLTDYMIP-QVIEIETVPVL 530
+V+ ++ N ++A+ T+ EA +++AEL + L +YM+P VI + P+
Sbjct: 3165 LVVAQADKAGNQRLIAYGKTVQAEASKEDVIASLKAELAAVLPEYMVPANVILVSEWPLT 3224
Query: 531 VNGKV 545
NGK+
Sbjct: 3225 PNGKI 3229
Score = 106 bits (255), Expect = 3e-22
Identities = 64/185 (34%), Positives = 105/185 (56%), Gaps = 10/185 (5%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-- 188
+VPIG PI N +Y+LD+ + + +G GE+ + G LARGY+ + RFI NP
Sbjct: 861 SVPIGKPIQNIQLYILDDELNLLPQGACGELHIGGDGLARGYLNRPELTQERFIANPFYQ 920
Query: 189 -NTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
+ +LY+TGD + G I Y GR D QVKIRG R++L E+++ V+ +D+
Sbjct: 921 AEEGNSSERLYKTGDLVRYKEDGNIEYMGRLDHQVKIRGFRIELGEIEYQVAQHKQIDSA 980
Query: 363 VVLCYGVESSNPEILAFV-TINPEARMS--AKNIEAELTSSLTDYMIP-QVIEIETVPVL 530
+V+ ++ N ++A+ T+ +A +++AEL + L +YM+P VI + P+
Sbjct: 981 LVVAQADKAGNQRLIAYAKTVQADASKEDVIASLKAELAAVLPEYMVPANVILVSEWPLT 1040
Query: 531 VNGKV 545
NGK+
Sbjct: 1041 PNGKI 1045
Score = 103 bits (248), Expect = 2e-21
Identities = 64/183 (34%), Positives = 100/183 (54%), Gaps = 9/183 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197
+ IG P+ + ++ LLDE++ V +G GE+ VAG LARGY+ + RFI NP+
Sbjct: 1957 ITIGKPLRDQHILLLDESLNLVPKGCAGEIYVAGAGLARGYLNREALSAERFIANPYYHE 2016
Query: 198 PNF---AKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
+LY+ GD D +G + Y GR D QVKIRGHR++L EV+ ++ + VD+ +
Sbjct: 2017 AGAWLGERLYKAGDLARYDAEGELHYLGRLDDQVKIRGHRIELGEVESRITQLEMVDSAL 2076
Query: 366 VLCYGVESSNPEILAFVTINPEARMS--AKNIEAELTSSLTDYMIPQVI-EIETVPVLVN 536
VL + +++A+V + + ++ L+ L YM+P VI I P+ N
Sbjct: 2077 VLALPGVDAQLQLVAYVKVIDTFKEGDWQAQLKQTLSQQLQAYMLPSVIVPITQWPLTNN 2136
Query: 537 GKV 545
GKV
Sbjct: 2137 GKV 2139
>UniRef50_P45745 Cluster: Dimodular nonribosomal peptide synthetase;
n=25; Bacillus|Rep: Dimodular nonribosomal peptide
synthetase - Bacillus subtilis
Length = 2378
Score = 107 bits (256), Expect = 2e-22
Identities = 62/177 (35%), Positives = 98/177 (55%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI N VY+LD ++ V G GE+ +AG LARGY D RF+ +P+ P
Sbjct: 771 PIGKPIWNTQVYVLDNGLQPVPPGVVGELYIAGTGLARGYFHRPDLTAERFVADPYG--P 828
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD G + Y GRAD Q+KIRG R++L E+D ++ P ++ V+
Sbjct: 829 PGTRMYRTGDQARWRADGSLDYIGRADHQIKIRGFRIELGEIDAVLANHPHIEQAAVVVR 888
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + + A+V +A + + + +SL DYM+P +E++ +P+ NGK+
Sbjct: 889 EDQPGDKRLAAYVV--ADAAIDTAELRRYMGASLPDYMVPSAFVEMDELPLTPNGKL 943
Score = 95.5 bits (227), Expect = 7e-19
Identities = 62/176 (35%), Positives = 94/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG I + VY+LDE ++ V G GE+ V+G LARGY+ G RFI +P P
Sbjct: 1846 IGCGIPDLGVYVLDERLQPVPPGVAGELYVSGAGLARGYLGRPGLTSERFIADPFG--PP 1903
Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++YRTGD L G + Y GRAD QVKIRG R++L E++ A+ P +++ V+
Sbjct: 1904 GTRMYRTGDVARLRADGSLDYVGRADHQVKIRGFRIELGEIEAALVQHPQLEDAAVIVRE 1963
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + + A+V I E + L DYM+P + ++ +P+ NGK+
Sbjct: 1964 DQPGDKRLAAYV-IPSEETFDTAELRRYAAERLPDYMVPAAFVTMKELPLTPNGKL 2018
>UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces
filamentosus|Rep: Peptide synthetase 1 - Streptomyces
filamentosus (Streptomyces roseosporus)
Length = 5830
Score = 106 bits (255), Expect = 3e-22
Identities = 63/178 (35%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNTH 197
VP+G P N Y+LD + V +G GE+ +AG LARGYV P RF+ +P
Sbjct: 757 VPLGRPTLNRRGYVLDPALEPVPDGTTGELYLAGEGLARGYVAAPGPTAERFVADPFG-- 814
Query: 198 PNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +++YRTGD G +L + GRAD QVK+RG R++L EV A++ +P V VL
Sbjct: 815 PPGSRMYRTGDLVRRRSGGMLEFVGRADGQVKLRGFRIELGEVQAALTALPGVRQAGVLI 874
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+P ++ ++ P A A + A L +L +M+P ++ + +P+ NGK+
Sbjct: 875 REDRPGDPRLVGYIVPAPGAEPDAGELRAALARTLPPHMVPWALVPLPALPLTSNGKL 932
Score = 101 bits (243), Expect = 8e-21
Identities = 63/178 (35%), Positives = 98/178 (55%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHP 200
PIG P+++ VY+LDE +R V G GE+ VAG LARGY+ RF+ +P++
Sbjct: 4464 PIGRPLADLQVYVLDERLRPVPPGTVGEMYVAGAGLARGYLGRPALTAERFVADPNSR-- 4521
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+ +LYRTGD + G + Y GR D QVKIRG R++L E++ A+ T V VVL
Sbjct: 4522 SGGRLYRTGDLAKVRPDGGLEYVGRGDRQVKIRGFRIELGEIEAALVTHAGVVQAVVLVR 4581
Query: 378 GVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
++ + ++A V P + + L ++L YM+P ++ +P+ NGK+
Sbjct: 4582 DEQTDDQRLVAHVVPALPHRAPTLAELHEHLAATLPAYMVPSAYRTLDELPLTANGKL 4639
Score = 101 bits (242), Expect = 1e-20
Identities = 67/179 (37%), Positives = 95/179 (53%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V IG P+ N V++LD +R V G GE+ VAG LARGY+ G RF+ P
Sbjct: 1816 VAIGRPLRNTRVFVLDGGLRAVPVGVVGELHVAGEGLARGYLGQPGLTAERFVACPFGDA 1875
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G++ + GR D QVK+RG R++L EV+ AV+ P VD VV+
Sbjct: 1876 GE--RMYRTGDLVRWRADGMLEFVGRVDDQVKVRGFRIELGEVEAAVAACPGVDRSVVVV 1933
Query: 375 YGVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+VT EA A I L YM+P V+ ++ +P+ NGKV
Sbjct: 1934 REDRPGDRRLVAYVTAAGDEAEGLAPLIVETAAGRLPGYMVPSAVVVLDEIPLTPNGKV 1992
Score = 99.1 bits (236), Expect = 6e-20
Identities = 63/180 (35%), Positives = 92/180 (51%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T IG P+ N V++LD + V G PGE+ +AG LARGY+R D RF+ NP
Sbjct: 5525 TPGIGTPLDNWRVHILDAALGPVPPGVPGEIHIAGSGLARGYLRRPDLTAERFVANPF-- 5582
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD G G + + GR D QVK+RG R++L +V+ A++ P V
Sbjct: 5583 APG-ERMYRTGDLGRFRPDGTLEHLGRVDDQVKVRGFRIELGDVEAALARHPDVGRAAAA 5641
Query: 372 CYGVESSNPEILAFVTINPEAR-MSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+V P R A + + L DYM+P + + T+P NGK+
Sbjct: 5642 VRPDHRGQGRLVAYVVPRPGTRGPDAGELRETVRELLPDYMVPSAQVTLTTLPHTPNGKL 5701
Score = 96.7 bits (230), Expect = 3e-19
Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P + +++++LD +R GE+ VAG LARGY+ D RF+ P +
Sbjct: 3393 VPIGRPFTGHHLFVLDPALRLTPPDTIGELYVAGDGLARGYLGRPDLTAERFVACPFRS- 3451
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD G + + GRAD QVKIRG R++L EV+ AV+ P V + +
Sbjct: 3452 PG-ERMYRTGDLARWRSDGTLEFIGRADDQVKIRGFRIELGEVEAAVAAHPHVARAIAVV 3510
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+VT + + +S+ + + L YM+P V+ ++ +P+ NGKV
Sbjct: 3511 REDRPGDQRLVAYVTGSDPSGLSSA-VTDTVAGRLPAYMVPSAVVVLDQIPLTPNGKV 3567
>UniRef50_Q0S1Z9 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 5496
Score = 106 bits (255), Expect = 3e-22
Identities = 61/178 (34%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P +N + Y+LD + V GE+ VAG LARGY RF+ NP+
Sbjct: 3890 VPIGTPQTNCHAYVLDHRLHPVPVAVVGELYVAGVQLARGYHNRPALTAERFVANPYG-- 3947
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD G + Y GR D QVK+RGHR++L E++ ++T P + + V
Sbjct: 3948 PPGERMYRTGDLVRWHPDGTLEYLGRRDLQVKLRGHRIELGEIEATLTTHPDITHAAVTV 4007
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ + ++ +V AR+ + A + L DYM+P I + + +P+ +GKV
Sbjct: 4008 HHDHHTGDRLVGYVVPRDGARLDPARVRALVADRLPDYMVPSPITVLDRLPLTASGKV 4065
Score = 103 bits (247), Expect = 3e-21
Identities = 61/178 (34%), Positives = 91/178 (51%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P +N + Y+LD + V GE+ VAG LARGY RF+ NP+
Sbjct: 4951 VPIGTPQTNCHAYVLDHRLHPVPVAVVGELYVAGVQLARGYHNRPALTAERFVANPYG-- 5008
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD G + Y GR D QVK+RGHR++L E++ ++T P + + V
Sbjct: 5009 PPGERMYRTGDLVRWHPDGTLEYLGRRDLQVKLRGHRIELGEIEATLTTHPDITHAAVTV 5068
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ + ++ +V A + I L DYM+P I I + +P+ NGK+
Sbjct: 5069 HHDHHTGDRLVGYVAPRNGAPLDPTTIHTFAADRLPDYMVPTPITILDALPLTTNGKI 5126
Score = 101 bits (243), Expect = 8e-21
Identities = 58/178 (32%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+ IG PI + Y+LD+ +R V G E+ +AG LARGY RF+ NP+
Sbjct: 778 ITIGGPIRGTHAYVLDDRLRPVPTGVTAELHLAGIQLARGYHNRPALTAERFVANPYG-- 835
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD G + + GR D Q+K+RGHR++L E++ ++T P + + V
Sbjct: 836 PPGERMYRTGDLVRWHPDGTLEFLGRRDLQIKLRGHRIELAEIEATLTTHPDITHAAVTV 895
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ + +++A+V P A++ + A L DYM+P I + + +P+ NGK+
Sbjct: 896 HKGPVTE-QLVAYVVPTPGAQIDPARVRAFAADRLPDYMLPDPITVLDRLPLTPNGKI 952
Score = 101 bits (243), Expect = 8e-21
Identities = 58/178 (32%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+ IG PI + Y+LD+ +R V G E+ +AG LARGY RF+ NP+
Sbjct: 2336 ITIGGPIRGTHAYVLDDRLRPVPTGVTAELHLAGIQLARGYHNRPALTAERFVANPYG-- 2393
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD G + + GR D Q+K+RGHR++L E++ ++T P + + V
Sbjct: 2394 PPGERMYRTGDLVRWHPDGTLEFLGRRDLQIKLRGHRIELAEIEATLTTHPDITHAAVTV 2453
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ + +++A+V P A++ + A L DYM+P I + + +P+ NGK+
Sbjct: 2454 HKGPVTE-QLVAYVVPTPGAQIDPARVRAFAADRLPDYMLPDPITVLDRLPLTPNGKI 2510
>UniRef50_A5FI40 Cluster: Amino acid adenylation domain; n=1;
Flavobacterium johnsoniae UW101|Rep: Amino acid
adenylation domain - Flavobacterium johnsoniae UW101
Length = 1992
Score = 106 bits (255), Expect = 3e-22
Identities = 65/179 (36%), Positives = 104/179 (58%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVPIG PI+N VY+LDE + + EG GE+ + G LARGY+ + +FI NP+
Sbjct: 841 TVPIGKPIANTEVYILDEYLNLLPEGAIGEIYITGAGLARGYLNRPELTAEKFIPNPYK- 899
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+Y+TGD G L G I Y GR D QVKIRG+R++L+E++ +S V + VV+
Sbjct: 900 --EGEIMYKTGDLGKWLADGNIEYTGRIDEQVKIRGYRIELEEIEKHLSLQDEVKHAVVV 957
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E+ + + L ++ + + + ++A L L +YMIP +++E++ + +GKV
Sbjct: 958 V--KENQDDKYLVAYYVS-DVELDKRKLQAALGKILPEYMIPGYFVQVESILMNTSGKV 1013
>UniRef50_A3DGP4 Cluster: Amino acid adenylation domain; n=1;
Clostridium thermocellum ATCC 27405|Rep: Amino acid
adenylation domain - Clostridium thermocellum (strain
ATCC 27405 / DSM 1237)
Length = 1833
Score = 106 bits (255), Expect = 3e-22
Identities = 62/185 (33%), Positives = 101/185 (54%), Gaps = 6/185 (3%)
Frame = +3
Query: 9 HIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN 182
H VPIG P+ N Y+LD++ + V G GE+ + G +ARGY+ + +FI N
Sbjct: 804 HAGSVVPIGRPLPNVKAYVLDKHRQPVPIGVVGELYIGGAGVARGYINEPEMTKQKFIPN 863
Query: 183 PHNTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359
P + P+ + +YRTGD L G I + GR D Q+KIRG+R+D +E++HA+ V +
Sbjct: 864 PFHPGPS-SYMYRTGDLVRYLPDGNIEFLGRIDRQIKIRGYRIDPEEIEHAIKEHSVVRD 922
Query: 360 CVVLCYGVESSNPEILAFVTIN--PEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVL 530
VV G + +++A++ ++ E + I L L +YM P + +++P+
Sbjct: 923 AVVTVRGNSEKSNKLVAYLVLDKKAEGNLDISEIRRYLKKKLPEYMRPSSFTVLDSIPLN 982
Query: 531 VNGKV 545
NGKV
Sbjct: 983 TNGKV 987
>UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular
organisms|Rep: Peptide synthetase - Mycobacterium
smegmatis
Length = 5990
Score = 106 bits (254), Expect = 4e-22
Identities = 67/178 (37%), Positives = 100/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
VPIG P+ ++LDE +R V G GE+ +AG + GYV G RF+ P
Sbjct: 5268 VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAGRGVGVGYVGRSGLTGTRFVACPFG-E 5326
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YRTGD D G + Y GRAD QVKIRG+R++L E+ A+S + VD VV+
Sbjct: 5327 PG-ARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIA 5385
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++ ++T + + +ELT+ L YM+P V+ +ET+P+ VNGK+
Sbjct: 5386 REDRPGDKRLVGYITGTADPAAA----RSELTNRLPAYMVPAAVVTLETLPLTVNGKL 5439
Score = 98.7 bits (235), Expect = 8e-20
Identities = 60/177 (33%), Positives = 94/177 (53%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG P+ +++LD+ +R EG GE+ VAG +A GY+ D RF+ P
Sbjct: 3775 PIGAPVPGAALFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETG 3834
Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD G + Y GRAD QVKIRG+R++L E+ A++ + VD VV+
Sbjct: 3835 E--RMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAR 3892
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++ ++T + L SL YM+P V+ ++T+P+ VNGK+
Sbjct: 3893 EDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKL 3945
Score = 93.1 bits (221), Expect = 4e-18
Identities = 63/179 (35%), Positives = 95/179 (53%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T PIGVP+ + ++LD +R V G GE+ VAG LA GY+ D RF+ P
Sbjct: 2270 TSPIGVPLEHLSFFVLDGWLRQVPVGVVGELYVAGEGLACGYISRSDLTSTRFVACPFGA 2329
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A++YRTGD G + Y GRAD QVKIRG+R++L EV A+ + V+ V+
Sbjct: 2330 -PG-ARMYRTGDLVRWGADGQLQYVGRADEQVKIRGYRIELGEVHAALVGLDGVEQAAVI 2387
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++ +VT + A L + YM+P ++ +E++P+ VNGK+
Sbjct: 2388 AREDRPGDKRLVGYVT----GAVDPVKARAALAERIPAYMVPAAIVVMESLPLTVNGKL 2442
Score = 84.6 bits (200), Expect = 1e-15
Identities = 56/180 (31%), Positives = 93/180 (51%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHN 191
+ VPIG + +++LD +R V G GE+ VAG + GY+ G RF+ P
Sbjct: 757 VVVPIGSALPRTALFVLDPWLRPVPTGVAGELYVAGDGVTCGYIGRSGLTASRFVPCPFG 816
Query: 192 THPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
P A++YRTGD + G + Y GRAD QVKIRG+R++L EV A++ + V++
Sbjct: 817 -EPG-ARMYRTGDLVRWGRDGQLEYLGRADEQVKIRGYRIELGEVQSALAALDGVESAAA 874
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + ++ ++T +I AEL L YM+P ++ + +P+ + K+
Sbjct: 875 IMREDRPGDRRLVGYIT----GTADPVDIRAELADRLPPYMVPTAIVVLPALPLTSSNKL 930
>UniRef50_Q4C9F4 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Crocosphaera watsonii WH 8501|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Crocosphaera watsonii
Length = 1569
Score = 106 bits (254), Expect = 4e-22
Identities = 62/181 (34%), Positives = 97/181 (53%), Gaps = 7/181 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD+ ++ G PGE+ + G +ARGY D RFI +P
Sbjct: 828 VPIGRPITNTEIYILDQYLQPTPIGVPGELYIGGLGVARGYFNRPDLTAERFIPHPFTRR 887
Query: 198 ---PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
P+ ++LY+TGD L G I Y GR D QVKIRG RV+L E++ + P V +
Sbjct: 888 QPTPSSSRLYKTGDLARYLSDGTIEYLGRIDDQVKIRGFRVELGEIEGILRQHPQVKEAI 947
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542
+ + P ++A+V A + + + L YM+P + + +++ P+ VNGK
Sbjct: 948 AVVQEDNNKIPRLVAYVV----AESEIEELRQFTSDKLPGYMVPTLFLTMDSFPLTVNGK 1003
Query: 543 V 545
+
Sbjct: 1004 I 1004
>UniRef50_Q1D3L3 Cluster: Non-ribosomal peptide synthase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 2091
Score = 106 bits (254), Expect = 4e-22
Identities = 64/180 (35%), Positives = 98/180 (54%), Gaps = 6/180 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VP+G P++N +++LD GE GE+ + G LARGY+R D F+ +P +
Sbjct: 331 VPMGAPVANTRLHVLDARGHLAAPGEVGELLIGGVGLARGYLRRPDLTAAAFVPDPFSEE 390
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LYRTGD + G + + GR D QVK+RG+RV+L E++ A+ P + VV+
Sbjct: 391 PG-ARLYRTGDLVRRMPDGTLQFLGRRDHQVKVRGYRVELGEIEAALLGHPGLREAVVVV 449
Query: 375 YGVESSNPEILAFV--TINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
G ++A+V N + + A L SL DYM+P V I ++ +P+ GKV
Sbjct: 450 RGEGEDEHRLVAYVVPARNAVEPLELTALRAFLERSLPDYMVPAVFIPLDGLPLTPTGKV 509
Score = 85.4 bits (202), Expect = 8e-16
Identities = 57/179 (31%), Positives = 93/179 (51%), Gaps = 7/179 (3%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
+G I N +Y+LD R V G GE+ + G +ARGY+ RF+ +P +
Sbjct: 1395 LGHAIDNTELYVLDTGGRPVPVGVAGELFIGGEGVARGYLGQPALTAERFVPDPFSARLG 1454
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LYRTGD + G + + GR D QVK+RGHR++L E++ ++ P V+ VV+
Sbjct: 1455 -ARLYRTGDLVRWREGGGLEFLGRIDHQVKVRGHRIELAEIETTLAGHPAVEQAVVVARV 1513
Query: 381 VESSNPEILAFVTINPEARMSAKNIEA---ELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+ P +N++A L+ L M+P V + + P+ NGKV
Sbjct: 1514 HAAEDVRLVAYFI--PRTGQDGRNVQALRQWLSERLPGPMVPTVFVPLACFPLTPNGKV 1570
>UniRef50_Q0PH94 Cluster: MassC; n=1; Pseudomonas fluorescens|Rep:
MassC - Pseudomonas fluorescens
Length = 3774
Score = 106 bits (254), Expect = 4e-22
Identities = 63/179 (35%), Positives = 100/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VP+G PISN +Y+LD + + G GE+C+ G +A+GY+ + +F+ NP N
Sbjct: 2937 SVPVGRPISNTQIYVLDAQLHLLPLGVSGEICIGGDGVAQGYLNRPELTAEKFVQNPFN- 2995
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A LYRTGD G G++ GR D QVKIRG R++L E++ ++T + VVL
Sbjct: 2996 -PG-ALLYRTGDLGRWSADGLLECIGRNDDQVKIRGFRIELGEIEARMATFAGIREGVVL 3053
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ T E + +++ A L + L YM+P + +E +P+ NGKV
Sbjct: 3054 AREDVPGDKRLVAYFTWAGEP-VGIESVRAYLQAHLPAYMVPSAFVALEHLPLTANGKV 3111
Score = 99.5 bits (237), Expect = 4e-20
Identities = 62/177 (35%), Positives = 98/177 (55%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+N VY+LD + R V G GE+ V G +ARGY+ + RF+ +P N
Sbjct: 866 IGKPIANAKVYVLDPHQRPVPLGVAGELYVGGKGVARGYLNRPELTAERFVRDPFNA--- 922
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++YRTGD L G + Y GR D QVKIRG R++L E++ ++ +P + V +
Sbjct: 923 -GRMYRTGDLVRWLPDGTLDYLGRNDDQVKIRGVRIELGEIETQLNQLPGILEAVAVV-- 979
Query: 381 VESSNPEILAFVTINPEA-RMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++A+ T NP+ ++ I A L + L DYM+P ++++ +P+ NGK+
Sbjct: 980 ---REERLVAYFTENPQLDPLTLAEIRAHLVAHLPDYMVPVAFMKLDALPLTANGKL 1033
Score = 91.5 bits (217), Expect = 1e-17
Identities = 57/177 (32%), Positives = 94/177 (53%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI+N +Y+LD ++ V G GE+ +AG +ARGY+ + RF+ +P
Sbjct: 1909 PIGKPIANTRLYVLDGQLQPVPLGVVGELFIAGVQVARGYLNRPELTAERFLDDPFTP-- 1966
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD L G + Y GR D QVKIRG R++L E+ ++ P V V+
Sbjct: 1967 --GRMYRTGDVSRYLPDGTLEYLGRNDDQVKIRGLRIELGEIQARLTEHPAVQEAAVI-- 2022
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A+ T P +++ A L L ++M+P + ++ +P+ NGK+
Sbjct: 2023 ---AREQRLIAYYTGVPS---EVESLRAHLLQHLPEFMLPASFVHLQVLPLSPNGKL 2073
>UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin
synthetase C-related non- ribosomal peptide synthetase
module; n=8; Proteobacteria|Rep: Arthrofactin
synthetase/syringopeptin synthetase C-related non-
ribosomal peptide synthetase module - Bradyrhizobium sp.
(strain BTAi1 / ATCC BAA-1182)
Length = 8646
Score = 106 bits (254), Expect = 4e-22
Identities = 62/179 (34%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PISN +Y+LD++ V G GE+ + G + RGY+ + RF+ + +
Sbjct: 1900 SVPIGRPISNTQIYILDQHGDPVPIGVAGEIHIGGVQVGRGYLNRPELTAERFVEDRFSG 1959
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A+LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+
Sbjct: 1960 EAG-ARLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHAAVRDAAVI 2018
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ +A + A+ + L + L DYM+P + +E +P+ NGK+
Sbjct: 2019 AREDAPGDQRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLERLPLTPNGKL 2075
Score = 105 bits (252), Expect = 7e-22
Identities = 61/179 (34%), Positives = 100/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PISN +Y+LD++ V G GE+ + G + RGY+ + RF+ + +
Sbjct: 7277 SVPIGRPISNTQIYILDQHGDPVPIGVAGEIHIGGVQVGRGYLNRPELTAERFVEDRFSG 7336
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A+LYRTGD G L+ G I Y GR D QVKIRG R++L E++ +S V + V+
Sbjct: 7337 EAG-ARLYRTGDLGRWLEDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVI 7395
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+ +A + A+ + L + L DYM+P + ++ +P+ NGK+
Sbjct: 7396 AREDVAGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTPNGKL 7452
Score = 103 bits (246), Expect = 4e-21
Identities = 60/179 (33%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++P+G PISN +Y+LD V G GE+ + G +ARGY+ + RF+ + +
Sbjct: 4056 SIPLGRPISNTRIYILDAYGDPVPIGVAGEIYIGGAGVARGYLNRPELTAERFVEDRFSG 4115
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A+LYRTGD G L+ G I Y GR D QVKIRG R++L E++ +S V + V+
Sbjct: 4116 EAG-ARLYRTGDLGRWLEDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVI 4174
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+ +A + A+ + L + L DYM+P + ++ +P+ NGK+
Sbjct: 4175 AREDVAGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTPNGKL 4231
Score = 102 bits (245), Expect = 5e-21
Identities = 61/176 (34%), Positives = 95/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PISN +Y+LDE+ G GE+ + G +ARGY+ + RF+ + +
Sbjct: 813 IGRPISNTQIYILDEHGEPAPIGVAGEIYIGGAGVARGYLNRPELTAERFVEDQFSGEAG 872
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+
Sbjct: 873 -ARLYRTGDLGRWLSDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHAGVRDVAVIARE 931
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ +A + A+ + L + L DYM+P + +E +P+ NGK+
Sbjct: 932 DAPGDQRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLERLPLTPNGKL 985
Score = 102 bits (245), Expect = 5e-21
Identities = 61/179 (34%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++P+G PISN +Y+LD V G GE+ + G +ARGY+ + RF+ + +
Sbjct: 5132 SIPLGRPISNTRIYILDAYGDPVPIGVAGEIYIGGAGVARGYLNRPELTAERFVEDRFSG 5191
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A+LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+
Sbjct: 5192 EAG-ARLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDVAVI 5250
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+ +A + A+ + L + L DYM+P + +E +P+ NGK+
Sbjct: 5251 AREDVAGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLERLPLTPNGKL 5307
Score = 100 bits (239), Expect = 3e-20
Identities = 60/176 (34%), Positives = 95/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG PISN +Y+LDE+ G GE+ + G +ARGY+ RF+ + +
Sbjct: 2982 IGRPISNTQIYILDEHGEPAPIGVAGEIYIGGAGVARGYLNRPALTAERFVEDRFSGEAG 3041
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+
Sbjct: 3042 -ALLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVIARE 3100
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+ +A + A+ + L + L DYM+P + ++ +P+ +NGK+
Sbjct: 3101 DVAGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTLNGKL 3154
Score = 100 bits (239), Expect = 3e-20
Identities = 60/176 (34%), Positives = 95/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG PISN +Y+LDE+ G GE+ + G +ARGY+ RF+ + +
Sbjct: 6214 IGRPISNTQIYILDEHGEPAPIGVAGEIYIGGAGVARGYLNRPALTAERFVEDRFSGEAG 6273
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+
Sbjct: 6274 -ALLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVIARE 6332
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+ +A + A+ + L + L DYM+P + ++ +P+ +NGK+
Sbjct: 6333 DVAGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTLNGKL 6386
Score = 97.9 bits (233), Expect = 1e-19
Identities = 59/176 (33%), Positives = 93/176 (52%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PISN +Y+LD G GE+ + G +ARGY+ + RF+ + +
Sbjct: 8360 IGRPISNTQIYILDAYGEPAPIGVAGEIYIGGAGVARGYLNRPELTAERFVEDRFSGEAG 8419
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+
Sbjct: 8420 -ARLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHAAVRDVAVIARE 8478
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ +A + A+ + L + L DYM+P + ++ +P+ NGK+
Sbjct: 8479 DGPGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTPNGKL 8532
>UniRef50_A3I9A7 Cluster: Peptide synthetase; n=1; Bacillus sp.
B14905|Rep: Peptide synthetase - Bacillus sp. B14905
Length = 1055
Score = 106 bits (254), Expect = 4e-22
Identities = 57/177 (32%), Positives = 98/177 (55%), Gaps = 2/177 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
++PIG PI+N +Y+++++ + GE+C+AG LA GY+ + PH P
Sbjct: 376 SIPIGRPIANYEMYVVNKDEQLCPVHVTGELCIAGAGLAAGYLHQPEKTAEAFVPHLFKP 435
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+ K+YRTGD +L GVI + GR DSQ+K+RG R++L E++ +S P + VV+
Sbjct: 436 D-QKMYRTGDLVRLLPSGVIEFVGRKDSQIKVRGFRIELGEIETVLSNHPIIQESVVIAK 494
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + A+ T ++ + + L + L DYM+P+ IE+ +P+ GK+
Sbjct: 495 KMSDGQNHLFAYYTAANGIQLEEQVLRDYLNNLLPDYMVPERFIELLEMPLSPTGKI 551
>UniRef50_Q83Z53 Cluster: Putisolvin synthetase; n=3; Bacteria|Rep:
Putisolvin synthetase - Pseudomonas putida
Length = 3066
Score = 105 bits (253), Expect = 5e-22
Identities = 58/177 (32%), Positives = 99/177 (55%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG P+ N +Y+LD + + V G PGE+ + G +ARGY+ RF+ +P
Sbjct: 684 IGRPVDNARLYVLDAHQQPVALGVPGELYIGGAGVARGYLNRPALTAERFLDDPFVATAG 743
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++YRTGD L G + Y GR D QVKIRG R++L E++ +S + +D VVL
Sbjct: 744 -GRMYRTGDLVRWLPDGTLDYLGRNDDQVKIRGVRIELGEIESRLSALAGIDEAVVLARE 802
Query: 381 VESSNPEILAFVTINPEAR-MSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ P ++A+ T + + ++ + + A+L + L +YM+P + ++ +P+ NGK+
Sbjct: 803 DQPGQPRLVAYFTAQADVKPLTPEGLRAQLQAHLPEYMVPVAFVALQALPLTANGKL 859
Score = 99 bits (238), Expect = 3e-20
Identities = 64/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI N VY+LD + V +G GE+ + G +A GY+ + RFI +P +
Sbjct: 1730 VPIGRPIGNTQVYVLDAWQQPVPQGVVGELYIGGDGVALGYLNRPELTAQRFIDDPFSQQ 1789
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LYRTGD G + GR D QVKIRG+R++L E++ ++ P V VV+
Sbjct: 1790 PG-ARLYRTGDLVRWQPDGQLECLGRNDDQVKIRGYRIELGEIEQQLALAPGVGEVVVMA 1848
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E ++A+ T EA + A + A L L +YM+P + + +P+ NG V
Sbjct: 1849 VPGEQGPLRLVAWFT-RLEAALQATELRAFLRGRLPEYMVPSAFVALPRMPLNNNGXV 1905
Score = 46.0 bits (104), Expect = 6e-04
Identities = 26/60 (43%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 168 RFIHNPHNTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTI 344
R +H H A+LYRTGD L G I Y GR D QVKI G R++L E+ ++ I
Sbjct: 2830 RTLHRRPVQHSPRARLYRTGDLARHLSDGNIEYLGRNDDQVKIHGLRIELGEIQAGLTRI 2889
>UniRef50_Q70P97 Cluster: MelC protein; n=4; Cystobacteraceae|Rep:
MelC protein - Melittangium lichenicola
Length = 1323
Score = 105 bits (253), Expect = 5e-22
Identities = 62/179 (34%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNT 194
++P G P+ N Y+LD+ + + PGE+ + G +ARGY R + RFI +P
Sbjct: 826 SIPYGRPMLNQRFYVLDDALASRPDYVPGELFIGGVGVARGYFRDDVRTAERFIVHPKTN 885
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LYRTGD G L G I + GR D QVK+ GHR++L E++ A+ P + VV
Sbjct: 886 E----RLYRTGDLGRFLPGGDIEFLGRKDFQVKVAGHRIELGEIEAALLRHPALREAVVA 941
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
G S+ + V +A SA+++++ L ++L YM+P + + +E +P+ NGKV
Sbjct: 942 APGERSARRLVAYVVVAEGQAVPSAESLQSFLGATLPQYMVPGIFVHLERLPLSSNGKV 1000
>UniRef50_A4JPB0 Cluster: Amino acid adenylation domain; n=1;
Burkholderia vietnamiensis G4|Rep: Amino acid
adenylation domain - Burkholderia vietnamiensis (strain
G4 / LMG 22486) (Burkholderiacepacia (strain R1808))
Length = 533
Score = 105 bits (253), Expect = 5e-22
Identities = 66/179 (36%), Positives = 96/179 (53%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPHNT 194
TVPIG P++ V +LD + + VR GE GE+ G LA GY+ + R F+ +PH+
Sbjct: 319 TVPIGRPVTGTTVCVLDASGQPVRPGEVGELYAGGIGLALGYLNDPEKTRAVFVDDPHDR 378
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
KLYRTGD G + GR D QVKIRG+RV +++V ++T V++ +V
Sbjct: 379 D---RKLYRTGDLVREGHDGAYEFIGRVDRQVKIRGYRVSVEQVQQVLATADDVEDAIVD 435
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIE-TVPVLVNGKV 545
E ++AFV + + + L L YMIP VIE++ +P+ VNGKV
Sbjct: 436 VGRDELGEKRLVAFVQSSRDPAEVRAAVRRHLGRHLASYMIPDVIEVQVALPLTVNGKV 494
>UniRef50_A4FE18 Cluster: Non-ribosomal peptide synthetase; n=3;
Actinomycetales|Rep: Non-ribosomal peptide synthetase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 1083
Score = 105 bits (253), Expect = 5e-22
Identities = 68/179 (37%), Positives = 102/179 (56%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPHNTH 197
VP+G I N +VY++DEN+ V G PGE+ +G + RGYV D R F+ +PH
Sbjct: 556 VPLGPAIPNVHVYVVDENLDPVPLGAPGEIVFSGVCVGRGYVNDPDRTRLAFLADPH--R 613
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV-DNCVVL 371
P +LYR+GD G L +G + + GR DSQVKIRG R+++ E+++ + +P V D VV+
Sbjct: 614 PG-QRLYRSGDHGRWLPEGKLEFLGRRDSQVKIRGFRIEIGEIENTLLRVPGVRDGAVVV 672
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ S + AF + E + A + L SL +YM+P V E +P+ NGK+
Sbjct: 673 AERADLSK-HLAAFYSAPGE--LDAGMLRDTLAESLPEYMVPPVFHWRERLPLTANGKI 728
>UniRef50_A4BRH4 Cluster: Probable peptide synthetase protein; n=3;
Bacteria|Rep: Probable peptide synthetase protein -
Nitrococcus mobilis Nb-231
Length = 2660
Score = 105 bits (253), Expect = 5e-22
Identities = 66/186 (35%), Positives = 102/186 (54%), Gaps = 12/186 (6%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPH--- 188
+PIG PI+N +Y+LD + V G GE+ + G LARGY +G F+ NP
Sbjct: 1871 IPIGRPIANTRLYVLDARLEPVPPGVVGELYIGGAGLARGYAQGPALSAAAFVPNPFPKA 1930
Query: 189 ---NTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVD 356
P ++LYRTGD GV+ Y GR D QVK+RG RV+L E++ A+ ++P V
Sbjct: 1931 GLAGAGPG-SRLYRTGDLARWRADGVLEYVGRIDHQVKLRGFRVELAEIEVALESLPAVR 1989
Query: 357 NCVVLCYGVESSNPEILAFV--TINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPV 527
VV S ++ +V T+ P + ++A+L +L +YM+P Q++ +E +P+
Sbjct: 1990 EAVVTAREAPSGK-RLVGYVVPTVAPGRAGLTEELQAQLKEALPEYMVPAQLVVLEKLPL 2048
Query: 528 LVNGKV 545
NGK+
Sbjct: 2049 TPNGKL 2054
Score = 95.1 bits (226), Expect = 9e-19
Identities = 58/179 (32%), Positives = 96/179 (53%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+PIG P N +Y+LD ++ V G GE+C+AG + RGY+ + F+ +P+
Sbjct: 813 LPIGRPTDNTRLYVLDGQLQPVPVGVTGELCIAGAGVGRGYLHDPARTAQAFVPHPYAQT 872
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +LYR+GD GV+ Y GR+D QVK+RG R++L E++ + V VV+
Sbjct: 873 PG-ERLYRSGDLARWRADGVLEYVGRSDHQVKVRGFRIELGEIEARLLEHQGVREAVVVV 931
Query: 375 YGVESSNPEILAFVTINPEARMSAKN-IEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
S + V EA + ++A L ++ +YM+P Q++ +E +P+ NGK+
Sbjct: 932 REAPSGKHLVGYVVPTALEAGAELGDALKAHLKEAIPEYMVPGQIVVLEQLPLTPNGKL 990
>UniRef50_A1ZSC1 Cluster: Mixed type I polyketide synthase-peptide
synthetase, putative; n=1; Microscilla marina ATCC
23134|Rep: Mixed type I polyketide synthase-peptide
synthetase, putative - Microscilla marina ATCC 23134
Length = 2045
Score = 105 bits (253), Expect = 5e-22
Identities = 64/178 (35%), Positives = 102/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197
+PIG P N +Y+L+E + + GE GE+ +AG + RGY + + +F+ NP N
Sbjct: 1504 IPIGQPYQNTQLYVLNEQLEQLPVGEIGELYIAGDGVTRGYWKNEALTQEKFVDNPFN-- 1561
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +LY++GD + +G ++ GR D QVKIRG RV+L E++ +S P V VV+
Sbjct: 1562 PG-TRLYKSGDKAQWNAEGQLVCLGRVDQQVKIRGFRVELGEIEQVLSAHPLVLQAVVVA 1620
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ + N ++ AFVT + ++ A+ + L L +YMIP E ++ P+ VNGKV
Sbjct: 1621 QKI-NQNQQLKAFVTF--KVQVKAEALSVHLKERLPEYMIPANFELVDKFPLTVNGKV 1675
>UniRef50_A1G2S8 Cluster: Amino acid adenylation domain; n=1;
Salinispora arenicola CNS205|Rep: Amino acid adenylation
domain - Salinispora arenicola CNS205
Length = 2125
Score = 105 bits (253), Expect = 5e-22
Identities = 70/178 (39%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P+ N +++D V G PGE+CV+G LARGYV D RF NP+
Sbjct: 774 VPIGTPLRNMRAHVVDRWDELVPLGVPGELCVSGVGLARGYVGRGDLTAERFRPNPYARV 833
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P + YRTGD D GV+ + GR D QVKIRG RV+ EV+ AV T P V VV
Sbjct: 834 PG-ERWYRTGDLVRWRDDGVLEFVGRVDEQVKIRGVRVEPAEVEAAVRTHPDVGEAVVAA 892
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E + E++A+ +S +++ A L L MIP + ++ +P+ NGKV
Sbjct: 893 RRGELGDLELVAYTVPANGTPVSLESLAAHLADVLPAPMIPSNHVGLDVLPLTPNGKV 950
Score = 102 bits (244), Expect = 6e-21
Identities = 59/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG P+S Y+LD + V G PGE+C+ G LARGY+ + RF+ +PH+
Sbjct: 1832 MPIGRPVSGTRGYVLDAKLMPVPVGVPGELCLGGVRLARGYLNRPELTADRFVPDPHSGE 1891
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A+LYRTGD G I + GR D QVK+RG R++L E++ A++ P V VV
Sbjct: 1892 RG-ARLYRTGDLVRWRPDGTIEFIGRIDQQVKVRGFRIELGEIEAALAEHPAVQASVVAV 1950
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
V +++ +V + A L + +YM+P + + ++ +P+ + KV
Sbjct: 1951 REVGPGEKQLVGYVVPRVGPVPDVAGLRAHLRDRVPEYMVPARWVTLDALPLTASKKV 2008
>UniRef50_P40806 Cluster: Putative polyketide synthase pksJ; n=9;
Bacteria|Rep: Putative polyketide synthase pksJ -
Bacillus subtilis
Length = 5045
Score = 105 bits (253), Expect = 5e-22
Identities = 64/177 (36%), Positives = 103/177 (58%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+N +Y+ D + V G PGE+C+AG +A+GY + ++ RFI NP P
Sbjct: 1468 IGRPIANTQIYITDSQLAPVPAGVPGELCIAGDGVAKGYYKKEELTDSRFIDNPF--EPG 1525
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+KLYRTGD L G I Y GR D+QVKIRG R++L +++ +S P + CVV+
Sbjct: 1526 -SKLYRTGDMARWLTGGRIEYIGRIDNQVKIRGFRIELGDIESRLSEHPGILECVVV--- 1581
Query: 381 VESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + A+ T + A ++A+ + + ++L YM+P I+++ +P+ NGK+
Sbjct: 1582 --ADMDNLAAYYTAKHANASLTARELRHFVKNALPAYMVPSYFIQLDHMPLTPNGKI 1636
Score = 49.2 bits (112), Expect = 6e-05
Identities = 47/187 (25%), Positives = 85/187 (45%), Gaps = 13/187 (6%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
V IG PI + +++++ V EGE G V+G ++ GY + D + +
Sbjct: 374 VEIGSPIPGFSMRIVNDHNELVEEGEIGRFQVSGLSVTSGYYQRPDLNESVFTEDG---- 429
Query: 204 FAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN-----CVV 368
+ TGD G L G + GR + I G ++ AV +P ++ C V
Sbjct: 430 ---WFETGDLGFLRNGRLTITGRTKDAIIINGINYYSHAIESAVEELPEIETSYTAACAV 486
Query: 369 LCYGVESSNPEILAFVT---INPEARMS--AKNIEAELTSSL---TDYMIPQVIEIETVP 524
G S++ + FVT +N E +MS +NI++ ++ + +Y++P ++ E +P
Sbjct: 487 R-LGQNSTDQLAIFFVTSAKLNDE-QMSQLLRNIQSHVSQVIGVTPEYLLP--VQKEEIP 542
Query: 525 VLVNGKV 545
GK+
Sbjct: 543 KTAIGKI 549
>UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1;
Streptomyces avermitilis|Rep: Non-ribosomal peptide
synthetase - Streptomyces avermitilis
Length = 3686
Score = 105 bits (252), Expect = 7e-22
Identities = 65/178 (36%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P+ N VY+LD ++ V G GE+ V G +ARGY D RF+ +P+
Sbjct: 2882 VPIGRPLPNMRVYVLDSALQPVPVGVTGELYVGGTGVARGYAGRPDLTAERFLPDPYAAE 2941
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LYRTGD L G + + GR D QVKIRG+RV+L EV ++ P V + V
Sbjct: 2942 PG-ARLYRTGDLVRHLPDGNVEFLGRVDDQVKIRGYRVELGEVQAVLAEHPAVRDAFVTV 3000
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++ + T A + + A L DYM+P + +E +P+ NGKV
Sbjct: 3001 HEPVPGDRRLVGYWTPAAGAGARPEELAAHCAVRLPDYMVPSAFVALEALPLNANGKV 3058
Score = 101 bits (242), Expect = 1e-20
Identities = 57/176 (32%), Positives = 101/176 (57%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
+G P+++ VYLLD + + V G PGE+ V G +ARGY+ + RF+ +P+ P
Sbjct: 802 VGHPLADLRVYLLDADRQLVPVGVPGEIHVGGPGVARGYLNRPELTAERFVPDPYG--PA 859
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++LY++GD L G + + GR D QVKIRG R++L E++ A++ P V + VVL
Sbjct: 860 GSRLYKSGDLARRLPDGSLEFLGRIDDQVKIRGFRIELGEIETALAAHPQVRDAVVLVRE 919
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ T + + ++ + L + L +YM+P + ++ +P+ NGK+
Sbjct: 920 DTPGDKRLVAYTTPAADQAPAPGDLRSHLAARLPEYMVPAAFVALDALPLTTNGKL 975
Score = 93.5 bits (222), Expect = 3e-18
Identities = 60/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG P+ N VY+LD ++ V G GE+ V G +ARGY D RF+ +P+ T
Sbjct: 1839 LPIGRPLPNMRVYVLDPALQPVPVGVTGELYVGGTGIARGYAGRPDLTAERFLPDPYGTE 1898
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YRTGD G + + GR D QVKIRG+RV+L E+ ++ P + +
Sbjct: 1899 PG-ARVYRTGDLVRQRPDGNVEFLGRVDDQVKIRGYRVELGEIQAVLTAHPGIRDAF--- 1954
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545
V + + E+ + A A+ + L L DYM+P + ++ +P+ NGK+
Sbjct: 1955 --VTTVDGELAGYY-----APAGAEGVREHLADRLPDYMVPATLTALDALPLNANGKI 2005
>UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Rep:
Iturin A synthetase A - Bacillus subtilis
Length = 3982
Score = 105 bits (252), Expect = 7e-22
Identities = 61/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P +N +Y+ D + V G GE+ ++G +ARGY D +F+ NP+
Sbjct: 3261 VPIGTPAANTDIYVADASRNLVPIGVIGEIYISGPGVARGYWNRPDLTEEKFVENPYV-- 3318
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P AK+Y++GD L G ++Y GR D QVKIRGHR++L E++ A+ V V
Sbjct: 3319 PG-AKMYKSGDLAKRLKDGNLVYIGRVDEQVKIRGHRIELGEIEAAMHNAEAVQKAAVTV 3377
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E ++ A+ + ++A + +L+S L DYM+P + +E +P+ NGK+
Sbjct: 3378 KEEEDGLKQLCAYYV--SDKPIAAAQLREQLSSGLPDYMVPSYFVRLEHMPLTSNGKI 3433
>UniRef50_Q70C52 Cluster: Non-ribosomal peptide synthase; n=1;
Xanthomonas albilineans|Rep: Non-ribosomal peptide
synthase - Xanthomonas albilineans
Length = 1959
Score = 105 bits (252), Expect = 7e-22
Identities = 64/178 (35%), Positives = 100/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VP+G PI+N V++LDE +R + G GEV + + GY R G RFI NP+
Sbjct: 343 VPVGRPIANTKVHVLDEQLRPLPPGIMGEVHIESLGITHGYWRQGGLTAARFIANPYG-- 400
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++LYRTGD +LD G + GR D +VK+RG+RVD+++V+ A++ V V+
Sbjct: 401 PPGSRLYRTGDMARLLDNGTLELLGRRDYEVKVRGYRVDVRQVEKALAAHLQVAEAAVIG 460
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ S PE+LA+V + + ++ + L L YM+P + + +P L NGK+
Sbjct: 461 WPQGSPTPELLAYV-VPRQGVLNLDELRKLLQERLPTYMLPTRFQSLPALPRLPNGKL 517
Score = 105 bits (252), Expect = 7e-22
Identities = 64/178 (35%), Positives = 100/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VP+G PI+N V++LDE +R + G GEV + + GY R G RFI NP+
Sbjct: 1394 VPVGRPIANTKVHVLDEQLRPLPPGIMGEVHIESLGITHGYWRQGGLTAARFIANPYG-- 1451
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++LYRTGD +LD G + GR D +VK+RG+RVD+++V+ A++ V V+
Sbjct: 1452 PPGSRLYRTGDMARLLDNGTLELLGRRDYEVKVRGYRVDVRQVEKALAAHLQVAEAAVIG 1511
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ S PE+LA+V + + ++ + L L YM+P + + +P L NGK+
Sbjct: 1512 WPQGSPTPELLAYV-VPRQGVLNLDELRKLLQERLPTYMLPTRFQSLPALPRLPNGKL 1568
>UniRef50_Q6YK39 Cluster: Bacillomycin D synthetase C; n=4;
Bacillus|Rep: Bacillomycin D synthetase C - Bacillus
subtilis
Length = 2619
Score = 105 bits (252), Expect = 7e-22
Identities = 61/182 (33%), Positives = 105/182 (57%), Gaps = 5/182 (2%)
Frame = +3
Query: 15 FLTVPIGVPISNNYVYLLDENMRCVRE-GEPGEVCVAGFNLARGYVRGKD--PHRFIHNP 185
+ ++PIG PISN +Y+L ++ ++ G GE+C+AG LARGY+ + +F+++P
Sbjct: 580 YASIPIGKPISNIQLYILHADLEHMQPIGVAGELCIAGDGLARGYLNRPELTAEKFVNHP 639
Query: 186 HNTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
+ ++YRTGD L G I Y GR D QVKIRG+R+++ EV+ A +P +
Sbjct: 640 IASGE---RIYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIEIGEVEGAFFQLPVIKEA 696
Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539
+V+ ++ + A+ T + ++A + EL+ L YMIP +++E +P+ NG
Sbjct: 697 IVIAREIDGET-SLCAYYT--AQHALTAGELREELSRQLPSYMIPAYFVQLEEMPLTFNG 753
Query: 540 KV 545
K+
Sbjct: 754 KI 755
Score = 94.3 bits (224), Expect = 2e-18
Identities = 61/176 (34%), Positives = 94/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI Y+LDE G PGE+ VAG LARGY+ + +F+ +P
Sbjct: 2100 IGQPIPTLQAYILDEYQHIQVMGIPGELYVAGEGLARGYLNRPELTAEKFVEHPFAAGE- 2158
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
K+Y+TGD L G I Y GR D QVKIRG+R+++ EV+ A+ V VV+
Sbjct: 2159 --KMYKTGDVARWLPDGNIEYLGRIDHQVKIRGYRIEIGEVEAALLQSESVKEAVVIAIE 2216
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E S ++ A+ ++ + ++ ++ L + L YMIP +++E +P+ NGK+
Sbjct: 2217 EEGSK-QLCAY--LSGDDSLNTAQLKRHLLNKLPAYMIPAYFVQMEKMPITANGKI 2269
>UniRef50_Q4U445 Cluster: DszC; n=3; Proteobacteria|Rep: DszC -
Polyangium cellulosum (Sorangium cellulosum)
Length = 3795
Score = 105 bits (252), Expect = 7e-22
Identities = 63/176 (35%), Positives = 96/176 (54%), Gaps = 2/176 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
VPIG ISN +++LD +R V G G++ + G LARGY+ + R P P
Sbjct: 1301 VPIGRAISNVEIHILDSALRPVPAGAEGDLYIGGVCLARGYLNRPELSRERFVPSPFDPG 1360
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LY TGD LD G I Y GR D+QVK+RG R++L E++ A+S V + VV
Sbjct: 1361 -ARLYNTGDRARTLDDGNIEYLGRLDAQVKLRGFRIELGEIEAALSAHEAVQDAVVAVQD 1419
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ +P+++A++ + ++A L L DYM+P + I +PV +GK+
Sbjct: 1420 AHTEDPKLVAYLVTGGRPFPAPGALKAYLKERLPDYMVPNRFAPIAQIPVTAHGKL 1475
>UniRef50_Q44103 Cluster: Peptide-synthetase; n=1; Amycolatopsis
mediterranei|Rep: Peptide-synthetase - Amycolatopsis
mediterranei (Nocardia mediterranei)
Length = 1324
Score = 105 bits (252), Expect = 7e-22
Identities = 67/176 (38%), Positives = 97/176 (55%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHPN 203
IG P+ + ++LDE +R G PGE+ + G LA GY G RF+ +P + P
Sbjct: 656 IGTPLPHLSAHVLDEWLRPCPAGVPGELYIGGGALAHGYWGRAGLTAQRFLPDPFSPVPG 715
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LYRTGD L G + Y GR DSQVKIRG R++L E++HA+ P V C V +
Sbjct: 716 -ARLYRTGDVARRLAGGGLEYVGRCDSQVKIRGFRIELGEIEHALGAHPAVGACAVTVH- 773
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ + A+VT P+ + A L SL ++MIP + + + +PV VNGK+
Sbjct: 774 ----DDRLAAYVTGGPD----HAELRAHLAKSLPEHMIPATVTVLDRLPVTVNGKL 821
>UniRef50_A7BRU4 Cluster: Non-ribosomal peptide synthetase; n=1;
Beggiatoa sp. PS|Rep: Non-ribosomal peptide synthetase -
Beggiatoa sp. PS
Length = 1010
Score = 105 bits (252), Expect = 7e-22
Identities = 68/179 (37%), Positives = 104/179 (58%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
VPIG PI+N+ Y+ D E +C G+ GE+CVAG L+RGY+ D +F+ NP
Sbjct: 327 VPIGKPIANSQAYIYDREGCQCP-VGQIGEICVAGEGLSRGYLNRPDLTVLKFVQNP--D 383
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +YRTGD G D+ G I ++GR+D+QVK+RGHR++L E+++ + + + VV
Sbjct: 384 MPG-TLMYRTGDLGYWDRNGNIHFSGRSDNQVKLRGHRIELGEIENTLQQLRGIREIVVK 442
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+GV + + + T E +S+ I L L YM+P + + +E +PV NGKV
Sbjct: 443 DWGV-GGDKYLCVYYTAARE--LSSNAIRIFLQERLPAYMVPSKFVWLEEMPVSWNGKV 498
>UniRef50_A4CG27 Cluster: Amino acid adenylation; n=2;
Pseudoalteromonas tunicata D2|Rep: Amino acid
adenylation - Pseudoalteromonas tunicata D2
Length = 340
Score = 105 bits (252), Expect = 7e-22
Identities = 64/185 (34%), Positives = 105/185 (56%), Gaps = 10/185 (5%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-- 188
+VPIG PI N +Y+LD+ + + +G GE+ + G LARGY+ + RFI NP
Sbjct: 125 SVPIGKPIQNIQLYILDDELNLLPQGACGELHIGGDGLARGYLNRPELTQERFIANPFYQ 184
Query: 189 -NTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
+ +LY+TGD + G I Y GR D QVKIRG R++L E+++ V+ +D+
Sbjct: 185 AEEANSSERLYKTGDLVRYKEDGNIEYMGRLDHQVKIRGFRIELGEIEYQVAQHKQIDSA 244
Query: 363 VVLCYGVESSNPEILAF-VTINPEARMS--AKNIEAELTSSLTDYMIP-QVIEIETVPVL 530
+V+ ++ N ++A+ T+ +A +++AEL + L +YM+P VI + P+
Sbjct: 245 LVVAQADKAGNQRLIAYGKTVQADAPKEDVITSLKAELAAVLPEYMVPANVILVSEWPLT 304
Query: 531 VNGKV 545
NGK+
Sbjct: 305 PNGKI 309
>UniRef50_A0YGI5 Cluster: Peptide synthetase; n=1; marine gamma
proteobacterium HTCC2143|Rep: Peptide synthetase - marine
gamma proteobacterium HTCC2143
Length = 1499
Score = 105 bits (252), Expect = 7e-22
Identities = 59/178 (33%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+ IG PI+N VY+LD+N+ + PGE+C+ G ++ GY + + RF+ TH
Sbjct: 773 ITIGRPIANTQVYVLDDNLNPLPVSVPGELCIGGAGVSLGYHQRPALNDDRFV-----TH 827
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD L G I + GR D QVK+RG+R++L E++ A+ + V+ VV
Sbjct: 828 PVLGRIYRTGDLAKALPNGEIQHLGRLDDQVKLRGYRIELGEIEMALKSCVEVEQAVVYL 887
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + ++A + + +I +L L YM+PQ + I +P+ NGKV
Sbjct: 888 LNLGEQDVRVVACCVPVADRALETISIRKKLRECLPSYMVPQYFLSISKIPLTPNGKV 945
>UniRef50_A0UVJ0 Cluster: Amino acid adenylation domain; n=2;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 1499
Score = 105 bits (252), Expect = 7e-22
Identities = 60/180 (33%), Positives = 105/180 (58%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
++VPIG+P N +Y+LD+N+ V GE+ V+G + RGY+ ++ RF+ NP
Sbjct: 764 VSVPIGIPADNIQIYILDKNLNPVPVETIGELYVSGAGVTRGYLNREELTKERFVDNPFI 823
Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
+K+Y+TGD L G I+Y GR+D QVK+RG+R++L E+++ + + + + +V
Sbjct: 824 KG---SKMYKTGDLAKHLHGGEIVYMGRSDYQVKLRGYRIELGEIENYLFSHNSITDAIV 880
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ E N + A++ + +S I L+S L DYM+P + ++++P+ NGKV
Sbjct: 881 IDRNDEKGNKYLCAYIVSTTDLDIS--EIRMFLSSKLPDYMLPSHFVILQSLPLTSNGKV 938
>UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide synthetase
protein; n=2; Proteobacteria|Rep: Probable non ribosomal
peptide synthetase protein - Ralstonia solanacearum
(Pseudomonas solanacearum)
Length = 5953
Score = 105 bits (251), Expect = 9e-22
Identities = 63/178 (35%), Positives = 101/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD + V G GE+ + G +ARGY+ + RF+ NP +
Sbjct: 1930 VPIGRPIANTQIYVLDAYRQPVPLGVTGEIYIGGAGVARGYLNRPELTAERFVVNPFHGE 1989
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G L G + Y GRAD+QVK+RG R++L E++ +S V VV
Sbjct: 1990 GR-ERMYRTGDLGRWLPDGSLEYQGRADAQVKLRGFRIELGEIEARLSQCAGVSEAVVAM 2048
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+ ++ EA + A+ + +L +SL +YM+P + +E +P+ NGK+
Sbjct: 2049 REDVPGEQRLVAYY-VSGEA-IEAQTLREQLQASLPEYMVPAAYVRLEHLPLTPNGKL 2104
Score = 103 bits (247), Expect = 3e-21
Identities = 63/178 (35%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD + V G GEV + G +ARGY+ + RF+ NP +
Sbjct: 3008 VPIGRPIANTQMYVLDAYRQPVPLGVTGEVYIGGAGVARGYLNRPELTAERFVENPFHGE 3067
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G L G + Y GRAD+QVK+RG R++L E++ + V VV
Sbjct: 3068 GR-ERMYRTGDLGRWLPDGSLEYQGRADAQVKLRGFRIELGEIEARLLQCAGVSEAVVTV 3126
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+ ++ EA + A+ + +L S L +YM+P + +E +P+ NGK+
Sbjct: 3127 REDAPGEQRLVAYY-VSGEA-IEAQTLREQLQSRLPEYMVPAAYVRLERLPLTPNGKL 3182
Score = 101 bits (243), Expect = 8e-21
Identities = 62/183 (33%), Positives = 103/183 (56%), Gaps = 9/183 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI+N +Y+LD + V G GE+ V G + GY+ + RF+ NP +
Sbjct: 870 IPIGRPIANTQIYVLDAYQQPVPLGVTGEIYVGGAGVGLGYLNRPELTAERFVVNPFHGE 929
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++Y+TGD G L G + Y GR D+QVK+RG R++L E++ ++S V VV+
Sbjct: 930 GR-ERMYKTGDLGRWLPDGSLEYQGRTDAQVKLRGFRIELGEIEASLSQCAGVSEAVVIV 988
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEA-----ELTSSLTDYMIPQV-IEIETVPVLVN 536
++A+ ++ EA +S + IEA +L +SL +YM+P +++E +P+ N
Sbjct: 989 REDTPGERRLVAYY-VSGEANVSGEAIEAQALREQLQASLPEYMVPAAYVKLERLPLTPN 1047
Query: 537 GKV 545
GK+
Sbjct: 1048 GKL 1050
Score = 101 bits (241), Expect = 1e-20
Identities = 61/176 (34%), Positives = 99/176 (56%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+N +Y+LD + V G GE+ + G +ARGY+ + RF+ NP +
Sbjct: 4054 IGRPIANTQIYVLDAYRQPVPLGVTGEIYIGGAGVARGYLNRPELTAERFVVNPFHGEGR 4113
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++YRTGD G L G + Y GRAD+QVK+RG R++L E++ +S V VV
Sbjct: 4114 -ERMYRTGDLGRWLPDGSLEYQGRADAQVKLRGFRIELGEIEARLSQCAGVSEAVVTMRE 4172
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+ ++ EA + A+ + +L +SL +YM+P + +E +P+ NGK+
Sbjct: 4173 DVPGEQRLVAYY-VSGEA-IEAQTLREQLQASLPEYMVPAAYVRLERLPLTPNGKL 4226
Score = 96.7 bits (230), Expect = 3e-19
Identities = 62/176 (35%), Positives = 98/176 (55%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG PI+N +Y+LD V G PGE+ V G +ARGY+ G RF+ +P +
Sbjct: 5108 IGRPIANTQIYILDAYGAPVPIGVPGEIHVGGACVARGYLHRPGLTAERFVADPFHGDGR 5167
Query: 204 FAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD G G I+Y GR D QVK+RG R++ E++ ++ V VVL
Sbjct: 5168 -ARMYRTGDLGCWQADGNIVYLGRNDHQVKLRGFRIEPGEIEARLAGCEGVREAVVLIRD 5226
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
P ++A+ + P A + A+ + A+L ++L YM+P + +E +P+ +GK+
Sbjct: 5227 DGVGEPRLVAYYS-GP-AALPAQALRAQLQAALPAYMVPAAYVYLERMPLTSSGKL 5280
>UniRef50_Q89T13 Cluster: Bll2237 protein; n=2; Bradyrhizobium|Rep:
Bll2237 protein - Bradyrhizobium japonicum
Length = 2154
Score = 105 bits (251), Expect = 9e-22
Identities = 59/178 (33%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VP+G P+ N +Y+LD N+ G GE+C+ G + RGY+ ++ RF+ +P
Sbjct: 1410 VPVGAPLPNTQLYVLDANLEPQPVGVTGELCIGGAGVGRGYINDPAQNKQRFLPDPF-LR 1468
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++LYRTGD G I GRAD QVK+RG+R++L+E+++A++ P V +V
Sbjct: 1469 QAASRLYRTGDLARRRADGTIECLGRADHQVKVRGYRIELKEIENALADHPSVRAGIVEP 1528
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
S + ++A + P +R+SA + L S L + IP + ++ VP+ +GK+
Sbjct: 1529 RREASGDVRLIAHIVARPGSRVSASELRDFLKSRLPGHAIPSAFLFMDQVPLNAHGKI 1586
Score = 50.4 bits (115), Expect = 3e-05
Identities = 39/166 (23%), Positives = 67/166 (40%), Gaps = 3/166 (1%)
Frame = +3
Query: 57 VYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAK-LYRTGDF 233
+ ++DE R + G GE+ + G N++RGY + T F +RTGD
Sbjct: 357 IAVMDETGRALASGAHGEIVLRGANMSRGYYNDEAA---------TQAAFRDGWFRTGDL 407
Query: 234 GILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVESSNPEILA 410
G LD G + GR + G ++ EV+ + + P V V + A
Sbjct: 408 GYLDADGYLFIVGRIKDVINRGGQKISPLEVEEVLLSHPAVLEAGVFAVPHPKLGENVAA 467
Query: 411 FVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545
V + + ++ + L Y +P +I + +P +GKV
Sbjct: 468 VVVLRANSEATSDQLRKFARKRLAAYKVPSLIRSVAALPKGASGKV 513
>UniRef50_Q4ZV19 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=6; Pseudomonadaceae|Rep: Non-ribosomal
peptide synthase:Amino acid adenylation - Pseudomonas
syringae pv. syringae (strain B728a)
Length = 2883
Score = 105 bits (251), Expect = 9e-22
Identities = 62/180 (34%), Positives = 101/180 (56%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNT 194
+VP+G P++N +LD + V E GE+ + G LA+GY+ RF+ +P
Sbjct: 814 SVPVGQPLANGKARVLDAYLNPVAERVAGELYLGGRGLAQGYLGRAAMTAERFVPDPD-- 871
Query: 195 HPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
N +LYR GD GV+ Y GRAD QVKIRG+RV+ EV + T+ V + VVL
Sbjct: 872 -ANGQRLYRAGDRARWVDGVLEYLGRADDQVKIRGYRVEPGEVGQLLQTLENVADAVVLA 930
Query: 375 YGVESSNP--EILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ES +++A+ A ++ +++ +L + L +Y++P Q++ +E +PV NGK+
Sbjct: 931 QPLESDETRLQLVAYCVAAAGASLNVESLRGQLAARLPEYLVPAQIMLLERLPVTANGKL 990
Score = 93.1 bits (221), Expect = 4e-18
Identities = 61/184 (33%), Positives = 98/184 (53%), Gaps = 8/184 (4%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHN 191
L+VPIG PI N ++LD+ + +G E+ + G LARGY RF+ +P +
Sbjct: 2312 LSVPIGRPIDNLKTHILDDGLLPAAQGVAAELYLGGVGLARGYHNRAALTAERFVPDPFD 2371
Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
+LYRTGD D GVI YAGR D QVKIRG R++L E++ + V V
Sbjct: 2372 EQGG-GRLYRTGDLARYRDAGVIDYAGRIDHQVKIRGLRIELGEIEARLHEHAAVREATV 2430
Query: 369 LCYGVESSNPEILAFVTINPEAR----MSAKNIEAELTSSLTDYMIP-QVIEIETVPVLV 533
+ ++ + + LA + +A + + ++A L + + DYM+P + I+++P+
Sbjct: 2431 I--DIDGPSGKQLAAYLVPTDATEAPDVLRERLQAHLKAHVPDYMVPGYFVFIDSMPLTA 2488
Query: 534 NGKV 545
NGK+
Sbjct: 2489 NGKL 2492
>UniRef50_Q2JA66 Cluster: Amino acid adenylation; n=15; Bacteria|Rep:
Amino acid adenylation - Frankia sp. (strain CcI3)
Length = 4489
Score = 105 bits (251), Expect = 9e-22
Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P+ N V++LD ++ V G GE+ VAG LARGY G RF+ P +
Sbjct: 772 VPIGRPMDNTRVFVLDRFLQPVPPGVTGELYVAGVGLARGYFGRPGLTGERFVACPFSGS 831
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G +G +++AGR D QVK+RG R++L EV+ + P V CVV+
Sbjct: 832 GE--RMYRTGDLGRWTGEGQLVFAGRVDGQVKVRGFRIELGEVEAVLGLYPGVGRCVVVV 889
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
E ++A+V + + I + L +YM+P V+ + +P+ GKV
Sbjct: 890 REDEPGQKRLVAYVVASEGEALDTVQIRDFVAGLLPEYMVPAVVVVLSGLPLTGQGKV 947
Score = 99.1 bits (236), Expect = 6e-20
Identities = 61/176 (34%), Positives = 95/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
+G P+ Y+LDE +R V G GE+ VAG LARGY+ RF+ P
Sbjct: 3965 VGGPLPGVRTYVLDEFLRPVPPGVVGELYVAGAGLARGYLNRPALTGERFVACPFGGSGE 4024
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++YRTGD G +++AGRAD+QVKIRG R++ E++ +S P VD V+
Sbjct: 4025 --RMYRTGDLARWTGDGGLVFAGRADAQVKIRGFRIEPGEIEAVLSGHPAVDQVAVVMRE 4082
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + ++A++ P + A I A + L +YM+P V+E+ +P+ NGK+
Sbjct: 4083 DQPGHRHLVAYLV--PHQEIGAAEIRAFVAGRLPEYMVPAVVVEVAELPLTANGKL 4136
Score = 91.9 bits (218), Expect = 9e-18
Identities = 60/178 (33%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI N +++LD +R V G GE+ +AG LARGYV RF+ P +
Sbjct: 1828 VPIGGPIWNVRLFVLDGFLRPVPPGVVGELYIAGVGLARGYVGRSSLTGERFVACPFSGS 1887
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD GV++Y GR D+QVKIRG R++L EV+ ++ V V+
Sbjct: 1888 GE--RMYRTGDLVRWRGDGVLVYVGRVDAQVKIRGLRIELGEVEAVLAGDGAVGRVAVVV 1945
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + ++A+V + A + L +YM+P V+E+ +P+ ++GK+
Sbjct: 1946 REDQPGHRYLVAYVVAAAGRGVDAAGLREFAARRLPEYMVPAAVVELAELPLTLSGKL 2003
Score = 83.4 bits (197), Expect = 3e-15
Identities = 56/178 (31%), Positives = 93/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V +G PI+ Y+LD+ ++ V G GE+ +AG LARGY G RF+ P +
Sbjct: 2885 VSLGTPIAGTRTYVLDDLLQPVPPGVVGELYLAGPGLARGYWARAGLTGERFVACPFSGS 2944
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YR+GD G +++ GRAD+Q+KIRG RV++ EV+ ++ P V VV+
Sbjct: 2945 GE--RMYRSGDLVRWTAAGELVFVGRADTQLKIRGFRVEVGEVEAVLAVFPGVTRVVVVA 3002
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++ +V + + AE L +Y++P V+ + +PV NGK+
Sbjct: 3003 REDRPGHRYLVGYVVPGDVDGRAVREFAAE---RLPEYLVPAGVVALPALPVTPNGKL 3057
>UniRef50_Q2JA64 Cluster: Amino acid adenylation; n=3;
Actinomycetales|Rep: Amino acid adenylation - Frankia sp.
(strain CcI3)
Length = 4606
Score = 105 bits (251), Expect = 9e-22
Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P+ N V++LD ++ V G GE+ VAG LARGY G RF+ P +
Sbjct: 767 VPIGRPMDNTRVFVLDRFLQPVPPGVTGELYVAGVGLARGYFGRPGLTGERFVACPFSGS 826
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G +G +++AGR D QVK+RG R++L EV+ + P V CVV+
Sbjct: 827 GE--RMYRTGDLGRWTGEGQLVFAGRVDGQVKVRGFRIELGEVEAVLGLYPGVGRCVVVV 884
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
E ++A+V + + I + L +YM+P V+ + +P+ GKV
Sbjct: 885 REDEPGQKRLVAYVVASEGEALDTVQIRDFVAGLLPEYMVPAVVVVLSGLPLTGQGKV 942
Score = 105 bits (251), Expect = 9e-22
Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P+ N V++LD ++ V G GE+ VAG LARGY G RF+ P +
Sbjct: 2300 VPIGRPMDNTRVFVLDRFLQPVPPGVTGELYVAGVGLARGYFGRPGLTGERFVACPFSGS 2359
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G +G +++AGR D QVK+RG R++L EV+ + P V CVV+
Sbjct: 2360 GE--RMYRTGDLGRWTGEGQLVFAGRVDGQVKVRGFRIELGEVEAVLGLYPGVGRCVVVV 2417
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
E ++A+V + + I + L +YM+P V+ + +P+ GKV
Sbjct: 2418 REDEPGQKRLVAYVVASEGEALDTVQIRDFVAGLLPEYMVPAVVVVLSGLPLTGQGKV 2475
Score = 95.5 bits (227), Expect = 7e-19
Identities = 61/178 (34%), Positives = 92/178 (51%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG PI N V++LD ++ V G GE+ VAG +ARGY+ G RF+ P
Sbjct: 3827 VPIGRPIRNARVFVLDSFLQPVPSGVVGELYVAGVGVARGYLNRPGLTAERFVACPFGG- 3885
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G ++Y GR DSQVK+RG+R++ EV+ ++ P V V+
Sbjct: 3886 ---GRMYRTGDLVRWSGAGQLVYVGRVDSQVKVRGYRIEPGEVEVVLAGCPGVGQVAVVV 3942
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
++A+V + I + L +YM+P V+ + +P+ VNGKV
Sbjct: 3943 REDLPGQRRLVAYVVPAGGVAVDTAGIRGFAAARLPEYMVPAVVVVLPVLPLTVNGKV 4000
>UniRef50_Q0SEB1 Cluster: Non-ribosomal peptide synthetase; n=2;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Rhodococcus sp. (strain RHA1)
Length = 2366
Score = 105 bits (251), Expect = 9e-22
Identities = 66/179 (36%), Positives = 98/179 (54%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHNT 194
VPIGV + Y+LD +R V G GE+ +AG ++ RGY R + P RFI +P
Sbjct: 1815 VPIGVVDPGKHAYVLDHALRPVPPGVSGELYLAGDSVTRGY-RNQSPKTAERFIADPFAV 1873
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +++YRT D + G I + GRADSQVK+RG R++L E++ +S P V++ VV+
Sbjct: 1874 -PG-SRMYRTSDVVWWGRDGQIYFTGRADSQVKVRGFRIELNEIEAVLSGDPDVEHIVVV 1931
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ T P R+ + S L DYMIP I ++ P L NGK+
Sbjct: 1932 VREDRPGDQRLVAYATSVPGGRIDPDQLHRRAASRLPDYMIPAAFIAVDEFPTLPNGKL 1990
Score = 97.9 bits (233), Expect = 1e-19
Identities = 60/180 (33%), Positives = 94/180 (52%), Gaps = 6/180 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V IGVP+ + Y+L +R V G GE+ V+G L+ GY+ D RF+ +P
Sbjct: 752 VDIGVPLGDLRTYVLGPGLRPVPPGVTGEIYVSGPGLSPGYLGRPDLTSGRFVADPF--A 809
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD D G + Y GR D Q+++RG+RV+L E+ A++ +P V V
Sbjct: 810 PGGTRMYRTGDLARYDATGTLHYHGRIDDQIQLRGYRVELGEIGAAMTAVPDVQAAVATA 869
Query: 375 YGVESSNPEILAFVTINPEARMSA--KNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + I+ +V P A + + A L SL YM P ++ ++ +P+ NGKV
Sbjct: 870 HEQAGGDQRIVGYVVPRPGGEHDAVEEQVRAHLVRSLPGYMTPSALVMLDRLPLTHNGKV 929
>UniRef50_Q9RFK5 Cluster: MtaG; n=4; Cystobacteraceae|Rep: MtaG -
Stigmatella aurantiaca
Length = 1750
Score = 105 bits (251), Expect = 9e-22
Identities = 62/179 (34%), Positives = 96/179 (53%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+PIG PI N +YLLD +++ V G PGE+ + G +ARGY+ + RFI +P
Sbjct: 1191 TLPIGRPILNTQMYLLDRHLQPVPMGVPGELLIGGEGVARGYLDRPELTATRFIPDPFGA 1250
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LYRTGD L G I + GR D QVK+RG R++ E++ A+ P + V+
Sbjct: 1251 EPG-ARLYRTGDLARYLPDGRIEFLGRMDQQVKVRGVRIEPGEIESALRLHPEIRQAAVV 1309
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + A+V P+A+++ + L L MIP I ++ +P+ N K+
Sbjct: 1310 ARADAAGEVSLAAYVVAGPDAQVAPSELRRFLKDKLPVSMIPDHFIRLDALPLTPNKKL 1368
>UniRef50_Q847C8 Cluster: NdaB; n=32; Cyanobacteria|Rep: NdaB -
Nodularia spumigena
Length = 1299
Score = 105 bits (251), Expect = 9e-22
Identities = 64/178 (35%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD ++ V G PGE+ + G LARGY+ + +FI NP
Sbjct: 798 VPIGRPIANTQIYILDSQLQPVPIGIPGELHIGGIPLARGYLNQPELTAQKFIPNPFGN- 856
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
KLY+TGD L G I Y GR D+QVK+RG R++L E++ + T P V VV+
Sbjct: 857 ---GKLYKTGDLARYLPDGNIEYLGRIDNQVKLRGLRIELGEIESVLDTHPQVGQTVVIL 913
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ N +++A+V + + ++ + L L YMIP + + P+ NGK+
Sbjct: 914 REDIAENKQLVAYV-LRKDQSLTPGELRRFLQDKLPGYMIPSAFVILLDFPLNPNGKI 970
>UniRef50_Q4CA71 Cluster: Amino acid adenylation; n=1; Crocosphaera
watsonii WH 8501|Rep: Amino acid adenylation -
Crocosphaera watsonii
Length = 1049
Score = 105 bits (251), Expect = 9e-22
Identities = 66/180 (36%), Positives = 101/180 (56%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
L+VPIG+PI N VY+L+ ++ + G GE+ + G LARGY+ D F+ NP
Sbjct: 760 LSVPIGLPIDNIQVYVLNAQLQLLPVGVVGELYLGGEGLARGYLNKPDLTAENFVPNPFK 819
Query: 192 THPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
A+LYRTGDF + G + Y GR D+QVKIRG R++L E++ +S P + CVV
Sbjct: 820 AG---ARLYRTGDFVRYQEDGNVEYVGRIDNQVKIRGVRLELGEIEAILSQHPDIIACVV 876
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
L + +LA++ + +S + + L + +Y IP V I +E+ P+ NGK+
Sbjct: 877 LAKEFAPGDRRLLAYIQTSQTEDIS-EELRQFLGERIPNYGIPSVFITLESFPLTNNGKL 935
>UniRef50_Q211M6 Cluster: Amino acid adenylation; n=1;
Rhodopseudomonas palustris BisB18|Rep: Amino acid
adenylation - Rhodopseudomonas palustris (strain BisB18)
Length = 2315
Score = 105 bits (251), Expect = 9e-22
Identities = 65/179 (36%), Positives = 95/179 (53%), Gaps = 3/179 (1%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTH 197
L++PIG PI N+ YLLD R + G GE+ V G LA GY+ + P
Sbjct: 782 LSIPIGTPIPNSTAYLLDPAGRPLPPGLVGEIWVGGDGLALGYMGDAELTAERFRPDLFA 841
Query: 198 P-NFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A++YRTGD G G I++ GRAD QVKIRG RV+L E++ ++ P V ++
Sbjct: 842 PAGEARMYRTGDLGRWRPDGNIVFLGRADKQVKIRGFRVELGEIEAMLALHPAVGGATII 901
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
S + +++A+VT P ++A + L L M+PQ I + +P+ NGKV
Sbjct: 902 APRRASGDRDLVAYVTPKPGTALTATELRNYLQERLPRQMLPQAYAILDRLPLTANGKV 960
>UniRef50_Q0B1F5 Cluster: Amino acid adenylation domain; n=1;
Burkholderia ambifaria AMMD|Rep: Amino acid adenylation
domain - Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 1304
Score = 105 bits (251), Expect = 9e-22
Identities = 62/175 (35%), Positives = 94/175 (53%), Gaps = 2/175 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
+P+G PI N ++YLLDE+ EG GE+CV+G LARGYV G+D + +
Sbjct: 564 LPVGRPIHNTHLYLLDEHGALAPEGCTGEICVSGIALARGYV-GRDDLTAAAFVDHPFES 622
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LYRTGD G+ L G + GR D QVKIRG+R+++ E++ A+ V + +V
Sbjct: 623 GERLYRTGDLGVWLPDGNLEVTGRRDMQVKIRGYRIEMGEIEAALRQHADVADAIVF--- 679
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGK 542
V P+ V A S + L L ++M+P ++ +E +P+ NGK
Sbjct: 680 VREDTPQHRQLVACVETATASVAGLREYLKERLPEFMVPGSIVTLERLPLTPNGK 734
>UniRef50_Q08MR4 Cluster: Linear gramicidin synthetase subunit D;
n=1; Stigmatella aurantiaca DW4/3-1|Rep: Linear
gramicidin synthetase subunit D - Stigmatella aurantiaca
DW4/3-1
Length = 336
Score = 105 bits (251), Expect = 9e-22
Identities = 62/177 (35%), Positives = 95/177 (53%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200
PIG PISN Y+LD+ M V G GE+ + G +LARGY+ +F+ +P +T P
Sbjct: 27 PIGRPISNAQAYVLDKGMNPVPVGVSGELFIGGDSLARGYLDRPALTAEKFLPHPFSTQP 86
Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++LYRTGD G + + GR D QVKIRG R++L E++ ++ P V VV+
Sbjct: 87 G-SRLYRTGDLVRWSAAGELEFLGRVDQQVKIRGFRIELGEIEAVLAQHPAVREAVVVVR 145
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+++ + EAR S + L L + M+P ++ +E +PV NGK+
Sbjct: 146 ESAPEVKQLVGYAVAQGEARPSKAELRTYLRERLPEPMVPSAIVLLEALPVTPNGKL 202
>UniRef50_A6LQ10 Cluster: Amino acid adenylation domain; n=1;
Clostridium beijerinckii NCIMB 8052|Rep: Amino acid
adenylation domain - Clostridium beijerinckii NCIMB 8052
Length = 4034
Score = 105 bits (251), Expect = 9e-22
Identities = 57/179 (31%), Positives = 97/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++P G+P+SN Y+L+ + G GE+C+ G LA GY+ +D FI+
Sbjct: 1442 SIPYGMPLSNQSFYVLNYENQICHIGVMGELCIGGLGLAEGYLNDEDKTTESFIN----- 1496
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
H +LY+TGD+G+L K G I + GR D Q+KI G+R++L E+++ + V N VV+
Sbjct: 1497 HKELGRLYKTGDYGVLHKEGYIEFFGRKDQQIKINGYRLELGEIENCILEYEGVRNSVVV 1556
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++ + A++ E +S + + L DYM+P + ++ +P+ NGKV
Sbjct: 1557 DRTHDNGRKYLCAYIV--GEKEISTTELREYIVELLPDYMVPSYFVMVDEIPLTANGKV 1613
Score = 103 bits (247), Expect = 3e-21
Identities = 56/177 (31%), Positives = 94/177 (53%), Gaps = 2/177 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
++P G+P++N Y+L+ N GE+ + G LA GY+ ++ +N HP
Sbjct: 2503 SIPYGIPLANQKFYVLNYNKDICPVEVIGELYIGGDGLAEGYMNDEEK---TNNAFINHP 2559
Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+ +LY TGD+G+L + G I + GR D Q+KIRG+RV+L E+ + + N VV+
Sbjct: 2560 DLGRLYNTGDYGVLHREGYIEFFGRKDQQIKIRGYRVELGEIQSGILEYKGIKNAVVVDK 2619
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E+ + A++ E +S + L L DYM+P + ++ +P+ NGKV
Sbjct: 2620 THENGRKYLCAYIV--GEKEVSITGVREYLEELLPDYMVPSYFVMVDEIPLTANGKV 2674
Score = 102 bits (245), Expect = 5e-21
Identities = 54/177 (30%), Positives = 96/177 (54%), Gaps = 2/177 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
++P G+P++N Y+L+ G GE+ + G LA GY+ ++ +N HP
Sbjct: 3565 SIPYGMPLANQKFYVLNYEKEVCPIGIAGELYIGGEGLAEGYMNDEEK---TNNAFINHP 3621
Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+ +LY TGD+G++ + G I + GR D Q+KIRG+RV+L E+++ + + N VV+
Sbjct: 3622 DLGRLYNTGDYGVMSREGYIEFLGRKDHQIKIRGYRVELGEIENRILEHQSIKNVVVIDR 3681
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + A+V + +S + L ++ DYMIP + ++ +P+ NGKV
Sbjct: 3682 SHSNGRKYLCAYVV--SDVDISVGELREHLGKTVPDYMIPSYFVILDKIPLTANGKV 3736
Score = 36.3 bits (80), Expect = 0.46
Identities = 40/177 (22%), Positives = 72/177 (40%), Gaps = 6/177 (3%)
Frame = +3
Query: 33 GVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAK 212
G PI + +V + D+ + + G V V G N+ Y + R T +
Sbjct: 373 GTPIKDCFVRISDDTGNILGDDCIGHVQVTGKNIINNYYTEEATARSF-----TSDGWLI 427
Query: 213 LYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGV--- 383
TGD G L+ G + GRA + + G + +++ I ++ V G+
Sbjct: 428 ---TGDIGFLENGHLTITGRAKDMIIVNGQNFYVNDIERVAEGIEQIEFGKVAACGIFDS 484
Query: 384 ESSNPEILAFVTIN---PEARMSAKNIEAELTSSLTDYMIPQVIEIETVPVLVNGKV 545
+S + + + FV N E I+ EL+ + I +VI + +P +GK+
Sbjct: 485 KSQSEKAVIFVENNEPIDEFVSLLLKIKNELSYKM-GIEISRVIPVREIPKTGSGKI 540
>UniRef50_A1G7W6 Cluster: Amino acid adenylation domain; n=2;
Salinispora|Rep: Amino acid adenylation domain -
Salinispora arenicola CNS205
Length = 1347
Score = 105 bits (251), Expect = 9e-22
Identities = 63/179 (35%), Positives = 95/179 (53%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
++P G + ++LD + R GEPGE+ + G LARGY+ DP + H HP
Sbjct: 907 SIPYGRALRAQSFHILDPDGRPCPVGEPGELFIGGDGLARGYIG--DPEQTAHR-FARHP 963
Query: 201 NFA-KLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD G G I + GR D QVKIRGHR++L E++ A+ P + C+V
Sbjct: 964 LLGERLYRTGDLGRWRTDGNIEFLGRVDRQVKIRGHRIELGEIEAALGRHPALRQCIVAA 1023
Query: 375 YGVESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
P + A+V +A +A + L L DYM+P + + ++++PV NGK+
Sbjct: 1024 VRGADERPRLAAYVVPKAGDAVPTADELAGTLRERLPDYMVPSKFLVLDSLPVTPNGKI 1082
>UniRef50_UPI000045C11E Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=3; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide
synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 2671
Score = 104 bits (250), Expect = 1e-21
Identities = 66/187 (35%), Positives = 101/187 (54%), Gaps = 15/187 (8%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN----PH- 188
IG PISN Y+LD+N++ V G PGE+ + G LA+GY+ D RFI++ P+
Sbjct: 1913 IGRPISNTQAYILDQNLQPVPIGVPGELHLGGAGLAQGYLNRPDLTQERFINSKFKIPYG 1972
Query: 189 ------NTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP 347
N+ +LY+TGD L G I Y GR D+QVKIRG R++L E++ ++ P
Sbjct: 1973 NAKVVQNSKLESERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIETVLNENP 2032
Query: 348 CVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVP 524
V VV+ + ++A++ + E + + LTS L DYMIP + + +P
Sbjct: 2033 AVFQAVVIAREDDPGVKRLVAYLVLKQEQTPTVTELRQFLTSKLPDYMIPAAFVFLAALP 2092
Query: 525 VLVNGKV 545
+ NGK+
Sbjct: 2093 MTPNGKI 2099
Score = 90.2 bits (214), Expect = 3e-17
Identities = 64/195 (32%), Positives = 99/195 (50%), Gaps = 23/195 (11%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP- 200
IG I+N VY+LD+ ++ V G PGE+ + G +LA GY+ + +FI NP N
Sbjct: 376 IGRAIANTQVYILDQYLQPVPIGVPGELHIGGDSLALGYLNRPELTQEKFIPNPFNNSKF 435
Query: 201 ----------NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP 347
+KLY+TGD L G I Y GR D+QVKIRG R++L EV+ +S P
Sbjct: 436 KIPYGNAKGVQNSKLYKTGDLACYLPDGNIEYLGRIDNQVKIRGFRIELGEVETTLSQHP 495
Query: 348 CVDNCVVL--------CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV 503
+ VL S + ++A++ + + ++ + L +L +YMIP
Sbjct: 496 SISQIAVLVREDIPGDTCTERSRSKRLVAYLVLKQDHVLTVSYLRQFLKETLPEYMIPAA 555
Query: 504 -IEIETVPVLVNGKV 545
+ +E +P+ NGKV
Sbjct: 556 FVFLEALPLTSNGKV 570
>UniRef50_Q2SHZ4 Cluster: Non-ribosomal peptide synthetase modules and
related protein; n=1; Hahella chejuensis KCTC 2396|Rep:
Non-ribosomal peptide synthetase modules and related
protein - Hahella chejuensis (strain KCTC 2396)
Length = 2624
Score = 104 bits (250), Expect = 1e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 10/181 (5%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHNTHP 200
IG PISN ++++DEN++ V G GE+ + G LARGY+ GK RFI NP +
Sbjct: 785 IGRPISNTLIHIIDENLQLVPRGVAGELLIGGRGLARGYL-GKPELTAQRFIANPFSGDL 843
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTI-----PCVDNC 362
+ +LYRTGD + + Y GR D QVK+RG R++L E++ ++ + V +C
Sbjct: 844 S-ERLYRTGDLVRVNSDDQLEYLGRIDQQVKVRGFRIELGEIESCINGLRDNGKKLVKDC 902
Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNG 539
VV +S P + A+V + A +++ L L YMIP+ +I ++ +P+ NG
Sbjct: 903 VVSVIKDDSLGPYLAAYVVSALGRSIDADDLKRRLARRLPGYMIPEAIIALDAIPLTANG 962
Query: 540 K 542
K
Sbjct: 963 K 963
Score = 85.8 bits (203), Expect = 6e-16
Identities = 58/178 (32%), Positives = 93/178 (52%), Gaps = 6/178 (3%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP-HNTHP 200
IG P+ +++ ++ + G PGE+ + G LA+GYV D RFI ++H
Sbjct: 1877 IGAPLCGVQLHIFNQLGQPAPAGAPGELYIGGVCLAQGYVGRDDLTSERFITTTIMSSHG 1936
Query: 201 NFA-KLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ +LYRTGD +G LY GR D QVKIRG RV+ EV+ +++ V V+
Sbjct: 1937 EISQRLYRTGDLARRTAQGEFLYLGRIDEQVKIRGFRVEPGEVEAVLNSHDDVKAAAVVA 1996
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + +LA++ A ++ A L L DYM P +++ +E +PV V+GK+
Sbjct: 1997 RD-DGAGMRLLAYIEPRHSAGFDVADLRAWLRKRLPDYMAPARILTLEKMPVTVSGKI 2053
>UniRef50_Q0PH95 Cluster: MassB; n=2; Pseudomonas fluorescens|Rep:
MassB - Pseudomonas fluorescens
Length = 4315
Score = 104 bits (250), Expect = 1e-21
Identities = 59/179 (32%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VP+G PISN +Y+LD ++ V G GE+C+ G +A+GY+ +F++NP
Sbjct: 1919 SVPVGRPISNTQIYVLDAQLQPVPLGITGEICIGGEGVAKGYLNRAQLTAEKFVNNPFVD 1978
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A +YRTGD G ++G++ GR D QVKIRG R++L E++ +++ + VL
Sbjct: 1979 QPG-ALMYRTGDLGRWSEEGLLECLGRNDDQVKIRGFRIELGEIEARLASCAGIQEVAVL 2037
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ T A + + A L L DYM+P + + ++P+ NGK+
Sbjct: 2038 AREDVPGDKRLVAYFTW-AGADLGIDQVHAHLQGQLPDYMLPSAYMPLASLPLTNNGKL 2095
Score = 95.1 bits (226), Expect = 9e-19
Identities = 58/183 (31%), Positives = 101/183 (55%), Gaps = 4/183 (2%)
Frame = +3
Query: 9 HIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHN 182
H+ PIGV I + +Y+LD + G GE+ V G +ARGY+ + + RF+ +
Sbjct: 862 HLVGMSPIGVRIPDLQLYVLDARREPLPLGVVGELYVGGAGVARGYLNREALNAERFVAD 921
Query: 183 PHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359
P ++Y+TGD G +L G + Y GR D QVK+RG R++L E+ ++T V +
Sbjct: 922 PATG----LRMYKTGDLGRLLADGSVEYLGRNDDQVKVRGFRIELGEIQAHLATANGVRD 977
Query: 360 CVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536
VV+ + + ++A+V + E ++A + L SL ++M+P + ++T+P+ N
Sbjct: 978 AVVIAREDQPGDKRLVAYVISDGELNVAA--LRDHLLRSLAEHMVPSAFVRLDTLPLTTN 1035
Query: 537 GKV 545
GK+
Sbjct: 1036 GKL 1038
Score = 94.3 bits (224), Expect = 2e-18
Identities = 60/177 (33%), Positives = 97/177 (54%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI+N +Y+LD ++ V G GE+ +AG +ARGY+ + RF+ +P
Sbjct: 4054 PIGKPIANTRLYVLDGQLQPVPLGVAGELFIAGVQVARGYLNRPELTAERFLDDPFTP-- 4111
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD G L G + Y GR D QVKIRG R++L E+ + P V + VV+
Sbjct: 4112 --GRMYRTGDLGRYLPDGTLEYLGRNDDQVKIRGLRIELGEIQARLIEHPAVKDAVVV-- 4167
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+ T P ++ A+L L D+M+P + + ++ P+ NGK+
Sbjct: 4168 ---ARDQRLVAYYTGAP---ADIDSLRAQLLQHLPDFMVPALFMHLDAWPLSPNGKL 4218
Score = 85.8 bits (203), Expect = 6e-16
Identities = 57/176 (32%), Positives = 95/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI+N Y+LD ++R V G GE+ V G +ARGY+ + RF+ +P N
Sbjct: 2990 IGRPIANATSYVLDAHLRPVPVGVAGELYVGGSGVARGYLNRPELTAERFLQDPFNA--- 3046
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++YRTGD L G + Y GR D QVK+RG RV+L E++ ++ + + VVL
Sbjct: 3047 -GRMYRTGDLVRWLPDGNLEYLGRNDDQVKLRGVRVELGEIESRLAALDGIREAVVLV-- 3103
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+LA+ T + + + + A L + L + ++P ++++ +P+ NGK+
Sbjct: 3104 ---REGRLLAWFT--EQRPLQIETLRAHLQAQLPEALVPVAYMQLDQLPLTANGKL 3154
>UniRef50_Q0LP44 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2596
Score = 104 bits (250), Expect = 1e-21
Identities = 65/180 (36%), Positives = 100/180 (55%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PI+N +Y+LD M+ V G GE+ + G NLARGY D RFI +P+ +
Sbjct: 2292 SVPIGRPIANTQLYILDARMQPVPVGVAGELLIGGLNLARGYAERPDLTAERFIPHPYAS 2351
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A+LYRTGD D G I Y GR D Q+K+RG RV+L E++H +S P + V
Sbjct: 2352 QAG-ARLYRTGDLARWRDDGAIEYLGRNDFQIKVRGIRVELGEIEHQLSQHPAIAQIV-- 2408
Query: 372 CYGVESSNPEILAFVTINPEARMSAKN-IEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
V +++A+ P+ + + + + L + L + MIP +++ +P+ NGK+
Sbjct: 2409 ---VHHHAGQLVAYWVARPDQAVPEETALRSWLRARLPEAMIPAHWLQLAELPLSSNGKL 2465
Score = 72.1 bits (169), Expect = 8e-12
Identities = 55/187 (29%), Positives = 90/187 (48%), Gaps = 15/187 (8%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH-- 197
IG PI + + +LD R G GE+ V G +A+GY+ + RFI +T
Sbjct: 775 IGCPIPDLALAVLDAQGRQAGVGVAGELYVGGAGVAQGYLERPELNAQRFIQADASTPDL 834
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+ ++ YR+GD G + Y GR D QVKIRG R++L E++ A+S V + V+
Sbjct: 835 PSNSRWYRSGDLVRYWPNGELEYLGRIDLQVKIRGFRIELGEIEAALSQHAAVQSAAVIV 894
Query: 375 YGVESSNPEILAFVTINPEAR---------MSAKNIEAELTSSLTDYMIPQ-VIEIETVP 524
+ ++ ++ + R + I +L L +YM P +IE+ + P
Sbjct: 895 REDRPGHKRLVGYLIAKTQMRSVGAQTDPSLDLAAINQQLRERLPEYMWPSALIELASFP 954
Query: 525 VLVNGKV 545
+ NGK+
Sbjct: 955 LTSNGKL 961
>UniRef50_A6YEH8 Cluster: CmnG; n=1; Saccharothrix mutabilis subsp.
capreolus|Rep: CmnG - Streptomyces capreolus
Length = 952
Score = 104 bits (250), Expect = 1e-21
Identities = 65/179 (36%), Positives = 96/179 (53%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
VPIGVP+ N +Y LD++ R G GE+ +AG LARGY + + H
Sbjct: 325 VPIGVPLPNYRLYALDDDGRLCPPGITGEIHIAGAGLARGYRSAEATAKAFHELEVHSGR 384
Query: 204 FAKLYRTGDFGIL----DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LYRTGD L D+ + + GR DSQVKI G+RV+L+EVD AV +P V + V+
Sbjct: 385 TERLYRTGDLARLVRHADRWALEFQGRVDSQVKISGYRVELEEVDAAVKAVPGVRDAAVV 444
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
G E + + +V P R+ ++ LT L Y++P ++ +E +P NGK+
Sbjct: 445 VRG-EPAEQLVCCYVGDVPPDRLRSR-----LTERLPAYLVPHLLVPVEALPFTRNGKM 497
>UniRef50_A4FCX9 Cluster: Non-ribosomal peptide synthetase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Non-ribosomal
peptide synthetase - Saccharopolyspora erythraea (strain
NRRL 23338)
Length = 1048
Score = 104 bits (250), Expect = 1e-21
Identities = 60/177 (33%), Positives = 97/177 (54%), Gaps = 3/177 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGKDPHRFIHNPHNTHP 200
V IG PI N Y++++ R V G PGE+C+AG +A GY+ R ++ R +
Sbjct: 747 VRIGEPIENTRFYVVNQRGRLVPPGVPGELCIAGDGVANGYLNRPEETERRFVDLAAAKG 806
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD + G +++ GR D Q+K+RGHRV+ E++H + P + VV
Sbjct: 807 FSERVYRTGDLVRQIADGSLVFLGRTDHQLKVRGHRVEAAEIEHVLRRHPSISEAVVTL- 865
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
++N ++A V + P+ +S++ + L SL YM+PQ + E P+ NGKV
Sbjct: 866 ---AANATLVAHVEVIPDGSVSSEELRDLLAPSLPGYMVPQRFVVHEEFPLTPNGKV 919
>UniRef50_A3IP47 Cluster: Peptide synthetase; n=2; Cyanobacteria|Rep:
Peptide synthetase - Cyanothece sp. CCY 0110
Length = 2942
Score = 104 bits (250), Expect = 1e-21
Identities = 65/177 (36%), Positives = 94/177 (53%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI N +YLLD N+ V G GE+ + G LARGY+ + +FI NP +
Sbjct: 851 IGHPIDNTQMYLLDSNLEPVPIGVAGELYIGGDGLARGYLNRPELTAEKFIPNPFDPTGK 910
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LY+TGD L G I Y GR D QVKIRG R++L E++ +++ P V VV+
Sbjct: 911 -TRLYKTGDLCRYLPDGNIEYIGRIDHQVKIRGFRIELGEIESLLTSHPEVQESVVIARE 969
Query: 381 VESSNPEILAFVTINPEARMSA-KNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ N ++A++ S + + L L DYMIP + IE +P+ NGK+
Sbjct: 970 DQPGNKRLVAYIVTQEVGEDSLNQTLRDYLKGQLPDYMIPSAFVFIEKLPLTPNGKI 1026
Score = 94.3 bits (224), Expect = 2e-18
Identities = 61/188 (32%), Positives = 102/188 (54%), Gaps = 14/188 (7%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P++N +Y+L++ ++ V G GE+ + G + +GY+ +FI++P +
Sbjct: 2377 VPIGRPVANTQLYILNQALKPVPVGAVGELHIGGVQVGKGYLNRPQLTAEKFINDPFSQD 2436
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A+LY+TGD L G I Y GR D QVKIRG R++L E++ ++ P V VV+
Sbjct: 2437 AE-ARLYKTGDLCRYLPDGNIEYLGRIDHQVKIRGFRIELGEIEGVLTQHPDVREVVVIV 2495
Query: 375 YGVESSNPEILAFVT--INPEARMSAKNIEAELTSS--------LTDYMIP-QVIEIETV 521
N +++A+V + P+ IE +L+ + L DYMIP + + ++
Sbjct: 2496 RQDHFDNKQLVAYVVSPLFPDDDEQVMTIEGKLSQALRDYLKDKLPDYMIPFAFVLLPSL 2555
Query: 522 PVLVNGKV 545
P+ NGK+
Sbjct: 2556 PLTPNGKI 2563
>UniRef50_UPI000045BE69 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide
synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 1401
Score = 104 bits (249), Expect = 2e-21
Identities = 56/179 (31%), Positives = 101/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
++P G P+SN +++LDE ++ + PG++ + G LA+GY R K FI +P
Sbjct: 857 SIPYGKPLSNQSIHILDEALQPRPDWVPGQIYIGGVGLAQGYWRDAAKTQASFIQHPRTG 916
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LY TGD G L G I + GR D QVKIRG+R+++ E++ + P + + V
Sbjct: 917 E----RLYCTGDLGRYLPDGNIEFLGRIDFQVKIRGYRIEIGEIETVLQQHPAIRSVAVS 972
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
G + + +++A++ E +++ + + L L +YMIP + + ++++P+ NGKV
Sbjct: 973 AVGEQRDDKQLVAYIVFEQEQSITSLELRSYLQQKLPEYMIPSMFMFMDSLPLSSNGKV 1031
>UniRef50_Q0SE34 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 4903
Score = 104 bits (249), Expect = 2e-21
Identities = 65/179 (36%), Positives = 95/179 (53%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
TVPIGVP + V +LD + V G PGE+ +AG LARGY+ G RF NP
Sbjct: 4372 TVPIGVPQNGVGVLVLDSRLHPVPIGVPGELYLAGAQLARGYLGQPGATAARFPANPWG- 4430
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD + G I Y GR D QVKIRG RV+L+E++ A+ V
Sbjct: 4431 -PPGQRMYRTGDVVSRRRDGTIDYLGRRDLQVKIRGQRVELEEIETALRRHAAVAQSAAA 4489
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
Y + ++ +V +P+ + + + AEL L YM+P Q++ + +P +GK+
Sbjct: 4490 VYESAGTGARLVGYVVPHPDMVVDTRAVSAELAQRLPRYMVPNQIVVLGALPSTPHGKL 4548
Score = 92.7 bits (220), Expect = 5e-18
Identities = 59/179 (32%), Positives = 92/179 (51%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+V IG PI N Y+LD +R V G GE+ +AG LARGY D RF+ +P
Sbjct: 2273 SVAIGRPIHNIRTYVLDSRLRPVPVGTRGELYLAGAYLARGYAGRPDLTAERFVADPFGE 2332
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
++YRTGD ++ G + Y GR D Q+K+RG RV+ E++ A+++ P V + V
Sbjct: 2333 --TGGRMYRTGDVVRWNESGRLEYLGRTDFQIKLRGQRVEPGEIESALTSDPAVTHAAVT 2390
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + ++A+V + I L L YMIP V+ + +P+ +GK+
Sbjct: 2391 VHRDAEAGDRLIAYVVAADGVPPDERRIVDRLAGLLPAYMIPSAVVPLPALPLTTSGKL 2449
Score = 72.9 bits (171), Expect = 4e-12
Identities = 53/178 (29%), Positives = 86/178 (48%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V IG PI V LLD + V G GE+ ++G +ARGY R RF+ +P
Sbjct: 3316 VTIGRPIRGAAVLLLDSRLHPVPTGVAGELYISGPGVARGYHRRPALTAARFVASPFGA- 3374
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ ++YRTGD G + G I Y R DSQ+++RG R++L E+D + P V
Sbjct: 3375 -SGERMYRTGDVGRWRRDGSIEYLHRNDSQIELRGVRIELGEIDATLLAHPTVRFAATDV 3433
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++++V + + + L ++P V+ ++ VP+ VNGK+
Sbjct: 3434 RELRDGVDALVSYVVPARNETVDPDQLIRFAATRLPMPLVPAIVVVVDAVPLTVNGKL 3491
Score = 71.7 bits (168), Expect = 1e-11
Identities = 52/178 (29%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNTH 197
V +G PI +LD +R V G GE+ VAG LARGY R + RF+ +P+
Sbjct: 764 VTVGRPIRGARAVVLDHRLRPVPVGVVGELYVAGTALARGYHRNARQTSERFVADPYG-- 821
Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD + Y GR+D QV +RG RV+ E+D + P V V +
Sbjct: 822 PPGTRMYRTGDTVRWTYDHELEYLGRSDEQVNLRGLRVEPGEIDATLLRYPAVRFAVTVI 881
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ +++++V + + ++ +++ + L++ L +++P V+ + +P+ +GK+
Sbjct: 882 RS-RGAGDQLVSYV-VGADT-VTEQDLLSFLSTELPPHLVPAAVVVLPDIPLTPSGKL 936
>UniRef50_A4F3K7 Cluster: Non-ribosomal peptide synthetase; n=3;
root|Rep: Non-ribosomal peptide synthetase - Planktothrix
agardhii NIVA-CYA 126
Length = 1622
Score = 104 bits (249), Expect = 2e-21
Identities = 63/177 (35%), Positives = 95/177 (53%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG P N VYLLD N + V G GE+ V+G LARGY + +FI NP +
Sbjct: 788 PIGKPAVNVKVYLLDSNFQPVPLGSIGELYVSGAGLARGYFNRPELTTEKFIPNPFD-QD 846
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++++LY+TGD L G I + GR D +VKIRG+ V+L E++ ++ P + VV Y
Sbjct: 847 SYSRLYKTGDLARYLSDGNIEFLGRIDDRVKIRGYSVELGELEAVLNKHPFLSQAVVKVY 906
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
G + + A+ ++ + + L L +YMIP + +E+ P+ NGKV
Sbjct: 907 GESAREKYLCAYFVPLQSQTITIEQLRHFLQEQLPEYMIPSAFVPMESFPLTSNGKV 963
>UniRef50_Q2SFM4 Cluster: Non-ribosomal peptide synthetase modules and
related protein; n=2; cellular organisms|Rep:
Non-ribosomal peptide synthetase modules and related
protein - Hahella chejuensis (strain KCTC 2396)
Length = 2853
Score = 103 bits (248), Expect = 2e-21
Identities = 65/180 (36%), Positives = 98/180 (54%), Gaps = 8/180 (4%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
+G PI+N +Y+LD+ +R +G GE+ VAG LARGY+ G RF+ +P
Sbjct: 775 VGRPIANTRIYVLDQALRYAPQGVTGELYVAGAGLARGYLTRPGMTAARFVADPEGQGD- 833
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+YRTGD G + + GR+D QVK+RG RV+L EV+HA+ +P V VV
Sbjct: 834 --LMYRTGDLVRWTPDGQLEFVGRSDRQVKVRGFRVELGEVEHALEALPGVSGAVVTAAT 891
Query: 381 VESSNPEILAFVTINPEARMSAK----NIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+S+ + A+ T+N R + + +L+ L DYM+P + I P+ VNGK+
Sbjct: 892 AGASH-RLTAYCTVNEGLRHDDEALRDRLYRQLSEMLPDYMMPSALAILPAWPLTVNGKI 950
Score = 85.4 bits (202), Expect = 8e-16
Identities = 57/188 (30%), Positives = 98/188 (52%), Gaps = 12/188 (6%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
L+VPIG P+ N + +LD+ +R G GE+ + G LA GY+ D RF+ +
Sbjct: 2316 LSVPIGRPVWNTQLRILDQWLRPAPVGVAGELYLCGAQLADGYLGRPDLTAARFVAD--- 2372
Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
T A++YRTGD L G + Y GR+D Q+KIRG R++L +++ A+ +P V VV
Sbjct: 2373 TEGEGARMYRTGDVARWLSNGDVEYLGRSDDQLKIRGQRIELGDIESALQNLPDVKRAVV 2432
Query: 369 LCYGVE--------SSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETV 521
+ + N +++ +V + + + A + L +L +M+P ++ +
Sbjct: 2433 CARVINNGEAAMAGADNRQLVGYVIPHAD-DIDADALRRRLAETLPAHMVPVAIVPVREF 2491
Query: 522 PVLVNGKV 545
P+ NGK+
Sbjct: 2492 PLSANGKL 2499
>UniRef50_Q6E7J8 Cluster: JamL; n=4; Bacteria|Rep: JamL - Lyngbya
majuscula
Length = 3935
Score = 103 bits (248), Expect = 2e-21
Identities = 62/186 (33%), Positives = 103/186 (55%), Gaps = 11/186 (5%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP--- 185
TVPIG PISN +Y+LD+ + G PGE+ V G +A+GY+ + +FI NP
Sbjct: 3617 TVPIGKPISNTQIYILDKYGNLLPPGIPGELYVGGDGIAQGYLSHPELTQEKFILNPFTK 3676
Query: 186 ----HNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPC 350
NT N +LY+TGD L G I + GR D+Q+K+RG R++L E++ ++
Sbjct: 3677 DKKSQNTEAN--RLYKTGDLARWLPDGNIEFVGRIDNQIKLRGFRIELGEIEALLNGHSQ 3734
Query: 351 VDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPV 527
+ VV+ N ++A++ + E+ +S K + L +YMIP + ++++P+
Sbjct: 3735 IQQAVVIAREDIPGNKRLVAYIVASDES-LSTKELREFTKQKLPEYMIPSAFVTLDSLPL 3793
Query: 528 LVNGKV 545
+ NGK+
Sbjct: 3794 MPNGKI 3799
>UniRef50_Q5MP00 Cluster: OnnI; n=1; symbiont bacterium of Theonella
swinhoei|Rep: OnnI - symbiont bacterium of Theonella
swinhoei
Length = 5052
Score = 103 bits (248), Expect = 2e-21
Identities = 63/182 (34%), Positives = 95/182 (52%), Gaps = 8/182 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+ IG PI N +Y+LD N V G PGE+C+ G LARGY+ + +F+ +P +
Sbjct: 1617 IVIGKPIQNTGIYILDHNRALVPIGVPGELCIDGDGLARGYLHKPELTAEKFMDHPFH-- 1674
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV-- 368
K+Y TGD L G I Y GR D QVKIRG R++L E++ + +P + + VV
Sbjct: 1675 -RGKKIYHTGDLARWLPNGTIEYLGRLDLQVKIRGFRIELGEIEFQLKQLPGIRDAVVVA 1733
Query: 369 --LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNG 539
+ +E + + F+ + + + A L L DYM+P I +E +P+ NG
Sbjct: 1734 KDMAKDMEGLHQLVAYFIPGGGPESVDTEVLRAGLKQKLADYMVPAFFIPLEEIPLTPNG 1793
Query: 540 KV 545
KV
Sbjct: 1794 KV 1795
>UniRef50_Q3WDU5 Cluster: Amino acid adenylation; n=1; Frankia sp.
EAN1pec|Rep: Amino acid adenylation - Frankia sp. EAN1pec
Length = 2547
Score = 103 bits (248), Expect = 2e-21
Identities = 61/176 (34%), Positives = 98/176 (55%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
+G PI V++LD+++R V G GE+ V+G LARGY+ G RF+ +P P
Sbjct: 1805 VGGPIPGLRVHVLDQHLRPVAPGGLGELYVSGGQLARGYLGRPGLTATRFVADPFGG-PG 1863
Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD G Y GRAD QVK+RG R++L E+ A++T P V+ VVL
Sbjct: 1864 -ARMYRTGDLARRTADGGFEYLGRADDQVKVRGFRIELGEIQAAIATHPAVEQAVVLARE 1922
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++ +V P R+ ++ + + L ++M+P V+ ++ P+ NGK+
Sbjct: 1923 DQPGQRRLVGYVVAAPGRRVDSEELRRHAAAMLPEFMVPVAVLALDAFPLTGNGKL 1978
Score = 87.4 bits (207), Expect = 2e-16
Identities = 55/177 (31%), Positives = 89/177 (50%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
+G PI + VYLLD + V G PGE+ + G +A GY+R G RF+ +P +
Sbjct: 668 VGRPIRSTQVYLLDTALAPVAPGMPGELYIGGAGVADGYLRRPGLTASRFVADPFSAG-- 725
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LYRTGD G + GR D QVK+RG R++ EV+ + P V C V+
Sbjct: 726 -GRLYRTGDLARWTADGELDVLGRVDDQVKVRGFRIEPGEVEAVLGRHPAVARCAVVARD 784
Query: 381 VESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A+V P + + L ++L ++M+P +++ +P NGK+
Sbjct: 785 DGPAGRHLVAYVVPAAPGTVVDPALLREHLAAALPEHMVPGAFVQLAALPTTPNGKL 841
>UniRef50_Q1D6B8 Cluster: Non-ribosomal peptide synthetase; n=5;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Myxococcus xanthus (strain DK 1622)
Length = 4567
Score = 103 bits (248), Expect = 2e-21
Identities = 62/176 (35%), Positives = 97/176 (55%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
+G P++N Y+LD ++ V G PGE+ + G LARGY+ + RFI NP +T
Sbjct: 4019 LGGPLANAQTYVLDAYLQPVPVGVPGELYIGGAGLARGYLNRPELTADRFIPNPFSTASG 4078
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LYRTGD L +G + + GR D QVK+RG R++L E++ A+ P V + VVL
Sbjct: 4079 -ARLYRTGDRARWLPQGELEFLGRIDFQVKLRGFRIELGEIESALRQHPAVRDTVVLVRE 4137
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+V P A + + L L ++M+P + +E +P+ +GKV
Sbjct: 4138 DTPGLQRLVAYVVAEPAATVDSGTFRPFLKERLPEHMMPSAFVTLEALPLNTSGKV 4193
Score = 100 bits (240), Expect = 2e-20
Identities = 60/180 (33%), Positives = 99/180 (55%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG P+ ++ Y+LD M V G PGE+ V G LA GY+ + +F+ +P ++
Sbjct: 2951 SVPIGRPLGHSTAYVLDSRMEPVPVGVPGELFVGGDGLAWGYLSRPELTAEKFLPHPFSS 3010
Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LYRTGD G + + GR+D QVK+RG R++L E++ + P V VVL
Sbjct: 3011 APG-ARLYRTGDRVRWRADGSLEFLGRSDFQVKVRGFRIELGEIESVLQQAPGVQEAVVL 3069
Query: 372 CYGVESSNPEILAFVTINPEAR-MSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V + A+ + + L +Y++P + I +E++P+ NGKV
Sbjct: 3070 AREDSPGDKRLVAYVVGEDGVESVDARALRDHVLRKLPEYLVPAIFIPMESLPLSANGKV 3129
Score = 99 bits (238), Expect = 3e-20
Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 6/178 (3%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
+G P++N Y+LD ++ V G PGE+ + G LARGY+ + RFI NP +T
Sbjct: 1891 LGGPLANAQTYVLDAYLQPVPVGVPGELYIGGAGLARGYLNRPELTADRFIPNPFSTASG 1950
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+LYRTGD L +G + + GR D QVK+RG R++L E++ A+ P V + VVL
Sbjct: 1951 -ARLYRTGDRARWLPQGELEFLGRIDFQVKVRGFRIELGEIESALRQHPAVRDTVVLVRE 2009
Query: 381 VESSNPEILAFVTINPEAR--MSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+V EA + + L L ++M+P + +E +P+ NGK+
Sbjct: 2010 DTPGLQRLVAYVVAEAEATTVVDSGTFRPFLKERLPEHMVPSAFVTLEALPLTPNGKL 2067
Score = 97.5 bits (232), Expect = 2e-19
Identities = 63/185 (34%), Positives = 98/185 (52%), Gaps = 10/185 (5%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG P+ ++ Y+LD M V G PGE+ V G LA GY+ + +F+ +P ++
Sbjct: 820 SVPIGRPLGHSTAYVLDSRMEPVPVGVPGELFVGGDGLAWGYLSRPELTAEKFLPHPFSS 879
Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LYRTGD G + + GR+D QVK+RG R++L E++ + P V VVL
Sbjct: 880 APG-ARLYRTGDRVRWRADGSLEFLGRSDFQVKVRGFRIELGEIESVLQQAPGVQEAVVL 938
Query: 372 CYGVESSNPEILAFVTINPEARMSAK------NIEAELTSSLTDYMIPQV-IEIETVPVL 530
+ ++A+ AR + I L + L +YM+P V + +E +P+
Sbjct: 939 AREDAPGDKRLVAYFVPTAAARSEEQAANAVGGIRTFLKARLPEYMLPAVFMPLEVLPLS 998
Query: 531 VNGKV 545
NGKV
Sbjct: 999 PNGKV 1003
>UniRef50_Q1D3K9 Cluster: Non-ribosomal peptide synthase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 2048
Score = 103 bits (248), Expect = 2e-21
Identities = 60/179 (33%), Positives = 101/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+V IG PI+N +Y+LDE++R V G GE+ + G +ARGY+ + RF+ +P
Sbjct: 845 SVAIGRPIANTRLYVLDEHLRLVPVGVHGELYIGGDGVARGYLDRPELTAERFVPDPFGD 904
Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LYRTGD GV+ + GR D QVK+RG+R++L E++ + P V VV+
Sbjct: 905 VPG-ARLYRTGDRVRRFPDGVLDFLGRRDEQVKVRGYRIELGEIEGVLGQAPGVREVVVV 963
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+V N A + + + + L ++++P V+ ++ +P+ NGKV
Sbjct: 964 AREDIEGSKRLVAYVVPNEGADVEPEVLRQLARAKLPEHLVPSVVVPLDALPLSPNGKV 1022
>UniRef50_O87314 Cluster: FxbC; n=5; Mycobacterium smegmatis|Rep: FxbC
- Mycobacterium smegmatis
Length = 4976
Score = 103 bits (248), Expect = 2e-21
Identities = 61/176 (34%), Positives = 101/176 (57%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG P+ ++LLD N++ V G GE+ +AG +ARGY G RF+ NP +
Sbjct: 1887 IGGPLPGLRIHLLDNNLQPVPAGVVGEMYIAGGQVARGYTGRPGLTATRFVANPFDGAGE 1946
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LYR+GD + D G ++Y GR+D+QVK+RG+R++L EV+ A+ T+P V N
Sbjct: 1947 --RLYRSGDLAMWTDAGELVYLGRSDAQVKVRGYRIELGEVEAALVTLPGVTNAAADVRH 2004
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ ++ +V + + A + + L L DYM+P V + ++ +P+ VNGK+
Sbjct: 2005 DDTGRARLIGYV-VGDALDIGA--LRSTLAERLPDYMVPSVLLRLDVLPLTVNGKL 2057
Score = 95.5 bits (227), Expect = 7e-19
Identities = 60/179 (33%), Positives = 95/179 (53%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
T +G PI N ++LD +R V +G PGE+ +AG LARGY+ G RF+ NP
Sbjct: 3412 TPTVGTPIWNTRAHILDNWLRPVPDGVPGELYIAGAGLARGYLGQPGLTASRFVANPFEP 3471
Query: 195 HPNFAKLYRTGDFGILDKGV-ILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
++YRTGD + I + GR D QVKIRG+RV+L +++ A+ + P V+
Sbjct: 3472 ----GRMYRTGDLVVRRADDNIDFLGRTDDQVKIRGYRVELGDIEAALVSTPASHRPRVI 3527
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIET-VPVLVNGKV 545
+ + ++A+V E ++ LT++L YM+P + T +P+ NGK+
Sbjct: 3528 ARPDTAGSSRLVAYVVPTTENPDVLDDLRMHLTATLPAYMVPTAMATLTEIPLTDNGKL 3586
Score = 80.6 bits (190), Expect = 2e-14
Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 11/186 (5%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
T +G PI N Y+LD +R V +G GE+ +AG LA GY R G + +P+
Sbjct: 379 TPTVGQPIWNTRGYILDAALRPVPDGAVGELYIAGTGLALGYHRRAGLTAATMVADPYV- 437
Query: 195 HPNFAKLYRTGDFGILDKG---VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
P ++YRTGD G ++ Y GR D QVKIRG+RV+L E++ ++ V C
Sbjct: 438 -PG-GRMYRTGDLVRRRPGSAELLDYLGRVDDQVKIRGYRVELGEIESVLTRADGVARCA 495
Query: 366 VLCYGVESSNP--EILAFVTIN---PEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPV 527
V+ ++ P + A+V + E + L L YM+P I +T+P+
Sbjct: 496 VVARATGANPPVKTLAAYVIPDRWPAEDAAFITGLRDHLARVLPGYMVPTRYGIVDTLPL 555
Query: 528 LVNGKV 545
+NGK+
Sbjct: 556 TINGKL 561
Score = 74.9 bits (176), Expect = 1e-12
Identities = 54/178 (30%), Positives = 90/178 (50%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGK-DPHRFIHNPHNTH 197
V +GVP N Y+LD+ + V G PGE+ +AG LA GY+ RG RF+ +P +
Sbjct: 4443 VALGVPGWNVRAYVLDDYLNPVPAGAPGELYLAGIQLADGYLHRGALTAARFVASPFD-- 4500
Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A++YRTGD G + Y GR+D Q+K+RG R++ E++ ++T P V + V+
Sbjct: 4501 -QGARMYRTGDVVRWRADGQLEYLGRSDDQIKLRGVRIEPGEIETVLATHPAVSSVRVIA 4559
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
G + A + A + ++L +M+P + + P+ +GK+
Sbjct: 4560 RGGRLMAYYVPA--GVEASAGELRDELREHAAAALPSHMVPSGFVALTEFPLTPSGKL 4615
>UniRef50_A3HT12 Cluster: Non-ribosomal peptide synthase; n=1;
Algoriphagus sp. PR1|Rep: Non-ribosomal peptide synthase
- Algoriphagus sp. PR1
Length = 1396
Score = 103 bits (248), Expect = 2e-21
Identities = 61/180 (33%), Positives = 98/180 (54%), Gaps = 3/180 (1%)
Frame = +3
Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGKDPHRFIHNPHN 191
F VPIG+ SN Y+LDE G GE+C+AG L +GY+ + + +F+ NP++
Sbjct: 799 FHKVPIGLATSNALAYVLDEQQELSPVGISGELCIAGAGLTKGYLSKSETDEKFLKNPYS 858
Query: 192 THPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
+ ++Y+TGD + K G+I Y GR D+QVKIRGHR++L E+ P V V
Sbjct: 859 --EVWDRIYKTGDLVRIQKDGLIEYLGRKDNQVKIRGHRIELAEIQELALQFPQVQMAVA 916
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
L +P+++ T ++ + + L L +M+P ++++E P+L NGKV
Sbjct: 917 LV--SNEKDPQLMLAYTSG--QKLEEGELISFLREKLPRFMVPDLLLQLEEFPLLPNGKV 972
>UniRef50_A0ZL89 Cluster: Non-ribosomal peptide synthase; n=1;
Nodularia spumigena CCY 9414|Rep: Non-ribosomal peptide
synthase - Nodularia spumigena CCY 9414
Length = 1490
Score = 103 bits (248), Expect = 2e-21
Identities = 64/179 (35%), Positives = 102/179 (56%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGKDPH-RFIHNPHNT 194
+V IG PI+N +Y+LD+N++ V G GE+ + G LARGY+ R + H +FI N T
Sbjct: 819 SVSIGSPIANTEIYILDQNLQPVPIGVFGELHIGGAGLARGYLNRPELTHEKFISNLIPT 878
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ ++LY+TGD L G I + GR D QVKIRG R++L E++ ++ P V V+
Sbjct: 879 AKS-SRLYKTGDLARYLPDGNIEFLGRIDYQVKIRGFRIELGEIEAVLAQHPLVKTSAVI 937
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++ + +I+A+V +A + N + L L DYMIP + + +P+ GK+
Sbjct: 938 VREIQLGSKQIVAYVVTQEDADIQT-NFRSFLQEKLPDYMIPAFFVRLAELPLTTTGKI 995
>UniRef50_Q8CJX2 Cluster: CDA peptide synthetase III; n=3;
Streptomyces|Rep: CDA peptide synthetase III -
Streptomyces coelicolor
Length = 2417
Score = 103 bits (247), Expect = 3e-21
Identities = 65/178 (36%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P VY+LD +R V G GEV +AG LARGY+ G RF +P
Sbjct: 783 VPIGTPHEGVRVYVLDSALRPVAPGLDGEVYLAGVQLARGYLGRGGLTAERFTADPFGA- 841
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +++YRTGD ++ G +++AGRAD QVK+RG+R++L E++ AV+ P V V+
Sbjct: 842 PG-SRMYRTGDVAHWNEAGELVFAGRADRQVKLRGYRIELGEIEAAVAGGPGVRQAAVVL 900
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V +P A L SL D+M+P + ++ +P+ NGK+
Sbjct: 901 REDRPGDQRLVAYVVPDP-GHWDEAAARARLALSLPDFMMPSAFVALDALPLSPNGKL 957
Score = 89.8 bits (213), Expect = 4e-17
Identities = 58/177 (32%), Positives = 92/177 (51%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI++ Y+LD+ ++ V G PGE+ V G LARGY+ RF+ P P
Sbjct: 1846 PIGRPIADTAGYVLDDALQPVPPGVPGELYVRGPGLARGYLGRPSLTAGRFVACPFG--P 1903
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+YRTGD G + Y GR D+QVK+RG RV+ E++ + +P V VL
Sbjct: 1904 AGGVMYRTGDLVRHRADGDLEYLGRTDTQVKLRGMRVEPAEIEAVTAGLPGVAQAAVLVR 1963
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++ +V + A + + L SL +YM+P ++ ++ +P+ NGK+
Sbjct: 1964 EDTPGDRRLVGYVVPDAGASVDPGALRQALRGSLPEYMVPAALVVLDALPLTTNGKL 2020
>UniRef50_Q7N3S1 Cluster: Complete genome; segment 9/17; n=1;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 9/17 - Photorhabdus luminescens subsp.
laumondii
Length = 916
Score = 103 bits (247), Expect = 3e-21
Identities = 62/186 (33%), Positives = 106/186 (56%), Gaps = 11/186 (5%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG P+SN ++LD + + E E GE+ +AG +ARGY+ +D F+
Sbjct: 370 SVPIGKPVSNTEFFILDHHYQLASEYEIGEIYIAGTQVARGYLNRQDLTEKHFLEIAIPP 429
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ +LYRTGD DK G +AGR D+Q+K+RG RV+L+E+ +A+ I V + +L
Sbjct: 430 NTQKIRLYRTGDLAYWDKEGNAHFAGRKDNQIKVRGMRVELEEIKNAIEVIDQVKHAAIL 489
Query: 372 C-YGVESSNPEILAFV-----TINPEARMSAKNI-EAELTSSLTDYMIP-QVIEIETVPV 527
+ + + A + TI +A+ +I +EL+ +L DYM+P + + ++T+P+
Sbjct: 490 AEKDPQHRSTRLTACIELADETIRQQAKYDITSILRSELSKTLPDYMLPDRFLFLDTMPL 549
Query: 528 LVNGKV 545
+GK+
Sbjct: 550 TSSGKI 555
>UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 11/17 - Photorhabdus luminescens subsp.
laumondii
Length = 5457
Score = 103 bits (247), Expect = 3e-21
Identities = 63/176 (35%), Positives = 97/176 (55%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P+ N VYLLD + V G GE+ + G +ARGY + F+ +P + +PN
Sbjct: 4904 IGRPLPNTRVYLLDVQGQPVPLGVEGELYIGGVGVARGYFNRAELTAEYFLTDPFSDNPN 4963
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD L G + + GR D QVKIRG RV+ E++ + P V VVL G
Sbjct: 4964 -ARMYRTGDLVRYLPDGNLEFLGRNDHQVKIRGFRVEPGEIEARLVEHPAVSQSVVLALG 5022
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E + ++A+V + R+ A ++ L++ L DYM+P + ++ P+ NGK+
Sbjct: 5023 -EGQDKRLVAYVVAQADERL-ANSLRTHLSAILPDYMVPSAFVRLDAFPLTPNGKL 5076
Score = 101 bits (242), Expect = 1e-20
Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI+N +YLL+ + V G GE+ V G +A GY+ D RF+ +P +
Sbjct: 1672 IPIGRPIANTRIYLLNAYGQPVPLGVTGEIYVGGDGVACGYLNRPDQTAERFLTDPFSDQ 1731
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+ A++YRTGD L G + + GR D QVKIRG R++ E++ + P V VL
Sbjct: 1732 PD-ARMYRTGDLARYLPDGNLEFLGRNDQQVKIRGFRIEPGEIEARLVEHPAVREAAVLA 1790
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
G + S+ ++A+V + A + L++ L DYM+P + +E P+ NGK+
Sbjct: 1791 LG-DGSDKRLVAYVAAEAHEGL-AMTLRDHLSAILPDYMVPSAFVRLEAFPLTPNGKL 1846
Score = 99 bits (238), Expect = 3e-20
Identities = 65/177 (36%), Positives = 97/177 (54%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG PI N VYLLD N + V G GE+ + G +ARGY+ RFI + N P+
Sbjct: 2751 IGRPIRNTRVYLLDRNRQPVPLGCVGEMYIGGVGVARGYLNRLALSEERFIPDVFNPVPD 2810
Query: 204 FAKLYRTGDFG--ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A++YRTGD +LD G + + GR D QVKIRG RV+L E++ + P V VL
Sbjct: 2811 -ARMYRTGDLARYLLD-GELEFLGRNDQQVKIRGFRVELGEIETRLVEYPAVQEAAVLAL 2868
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + ++A+V ++A+ + L++ L DYMIP + +++ P NGK+
Sbjct: 2869 D-DGQDKRLVAYVVAEANEGLAAR-LREYLSAVLPDYMIPVAFVRLDSFPQTPNGKL 2923
Score = 99.1 bits (236), Expect = 6e-20
Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI+N VYLLD + V G GE+ V G +A+GY+ + RF+ +P +
Sbjct: 3824 IPIGRPIANTRVYLLDVYGQPVPPGVIGEIYVGGDGVAQGYLNRPELTAERFLVDPFSDD 3883
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+ A++YRTGD L G + + GR D QVKIRG R++ E++ + P V VL
Sbjct: 3884 PD-ARMYRTGDLARYLPDGNLEFMGRNDQQVKIRGFRIEPGEIEARLVEHPAVREAAVLA 3942
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
G + + ++A+V + + ++ A L+ L DYM+P + ++ P+ NGK+
Sbjct: 3943 LG-DGPDKRLVAYVVALADDGL-VNSLRAYLSKILPDYMVPSAFVRLDAFPLTPNGKL 3998
Score = 80.6 bits (190), Expect = 2e-14
Identities = 54/176 (30%), Positives = 89/176 (50%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG P N +YLLD+ V G GE+ + G +ARGY+ RF+ + +
Sbjct: 602 IGRPAKNARIYLLDKYGELVPAGCVGEMYIGGVGVARGYLNRPALSVERFMLDTFSPVSG 661
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++YR+GD L G + + GR D QVKIRG R++L E++ ++ P V VL
Sbjct: 662 -ERMYRSGDLARYLPDGDLEFLGRNDEQVKIRGFRIELGEIETRLTEHPAVQEAAVLALD 720
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V + A ++ L++ L DYM+P + ++T P +GK+
Sbjct: 721 GDQGK-RLVAYVEAKANEGL-AVDLREYLSAILPDYMVPAAFVRLDTFPQTPSGKL 774
>UniRef50_Q20CI8 Cluster: CesB; n=7; cellular organisms|Rep: CesB -
Bacillus cereus
Length = 2681
Score = 103 bits (247), Expect = 3e-21
Identities = 62/179 (34%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++PIG PI+N+ Y+LD + G GE+CV G +A+GYV + RFI +P
Sbjct: 2135 SIPIGTPIANSSAYILDVHQNIQPIGVVGELCVGGDGVAKGYVNLEQLTEERFIADP--- 2191
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ +YRTGD+ +L G I Y GR D+QVKIRG R++L+ + + + + + +V+
Sbjct: 2192 FLKGSTMYRTGDYVKLLPNGNIQYIGRVDNQVKIRGFRIELEAIMNTLKQCESIKDVIVV 2251
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
V+ N + E +S + + A L +YM+P Q I IE +P+ +NGKV
Sbjct: 2252 ---VQEQNGYKTLVAYVVGEESLSIETVRAYAKKHLAEYMVPSQFIFIEEIPLSINGKV 2307
Score = 34.3 bits (75), Expect = 1.9
Identities = 21/87 (24%), Positives = 43/87 (49%)
Frame = +3
Query: 285 VKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAE 464
V+I+G RVDL++++ V+ + ++ C V+ + + AFV + +A E +
Sbjct: 13 VRIQGKRVDLKKIERQVAKVSFIEQCAVIARKQDDGEYLLTAFVV----SEKAAAKEELQ 68
Query: 465 LTSSLTDYMIPQVIEIETVPVLVNGKV 545
L L Q+I + ++P+ G +
Sbjct: 69 LLEVLPPK--SQIISMSSLPLTKEGTI 93
>UniRef50_Q1IA18 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Pseudomonas entomophila L48|Rep: Putative
non-ribosomal peptide synthetase - Pseudomonas
entomophila (strain L48)
Length = 2990
Score = 103 bits (247), Expect = 3e-21
Identities = 61/177 (34%), Positives = 98/177 (55%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200
PIG PI+N +Y+LD ++ G PGE+ +AG LARGY+ RF+ +P + P
Sbjct: 1409 PIGKPIANARLYVLDGDLNPQPVGVPGELYIAGHCLARGYLNRAPLSAERFLPDPFSPAP 1468
Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A++YR+GD +L G + Y GR D QVK+RG R++L E+D + P V + VL
Sbjct: 1469 G-ARMYRSGDLALLQADGNVQYLGRVDQQVKLRGFRIELGEIDSLLRQQPGVQDVAVLLR 1527
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ +P ++A+V A+ + A L L ++M+P + + +P+ NGK+
Sbjct: 1528 EDVAGDPRLVAYVV----GTGDAQTLRAALQRQLPEHMLPTAWVSLAQLPLTRNGKL 1580
Score = 89.0 bits (211), Expect = 6e-17
Identities = 58/179 (32%), Positives = 92/179 (51%), Gaps = 6/179 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH----RFIHNPHN 191
+PIG P++N VYL D + E GEV + G +ARGY+ PH RF+ NP
Sbjct: 353 LPIGRPLANCRVYLFDAQGQA---SEEGEVYLGGVGVARGYLNL--PHLTAERFVDNPFV 407
Query: 192 THPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
+LYRTGD L G + + GR D Q K+RG R++L E++ ++ +P V +V
Sbjct: 408 AGE---RLYRTGDLARLRADGQLEFLGRNDHQAKLRGLRLELGEIEARLAEVPGVRESLV 464
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542
P ++A+ + A ++ + +L L DYM+P +++ +P+ NGK
Sbjct: 465 QLRQDTPGEPRLVAYYARHEGAALTPAELSRQLRMHLPDYMVPSAFVQLPALPLTANGK 523
Score = 81.4 bits (192), Expect = 1e-14
Identities = 53/177 (29%), Positives = 90/177 (50%), Gaps = 2/177 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
++P G + + ++LD+ ++ G + + G LA+GY R DP + +
Sbjct: 2461 SIPYGQALDHQRFHVLDDALQVRPTWVTGHLYIGGIGLAKGYWR--DPALSARSFFDHPL 2518
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+LYRTGD G L G I + GR D+QVK++G+R++L E++ ++ P V + VV
Sbjct: 2519 TGERLYRTGDLGRRLPDGNIEFLGRDDNQVKVQGYRIELGEIETVLNRHPGVHSAVVRIL 2578
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
G E+ + LA + + + A + + L L YM+P +E P+ NGKV
Sbjct: 2579 G-EAQAQKRLAGYVLKADPALQAGDFNSYLADKLPAYMVPSSFTFVEAWPLSANGKV 2634
>UniRef50_Q0K0K4 Cluster: Non-ribosomal peptide synthetase; n=1;
Ralstonia eutropha H16|Rep: Non-ribosomal peptide
synthetase - Ralstonia eutropha (strain ATCC 17699 / H16
/ DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC
17699 / H16 / DSM 428 / Stanier337))
Length = 2008
Score = 103 bits (247), Expect = 3e-21
Identities = 65/177 (36%), Positives = 99/177 (55%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHP 200
PIG P+ Y+LD + V G PGE+ + G LARGY+ G RFI +P P
Sbjct: 825 PIGRPVGARSAYVLDSRLEPVPVGVPGELYLGGEGLARGYLGRAGMTADRFIPDPFGA-P 883
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+LYRTGD G I Y GR D QVKIRG R++L E++ + P V VVL +
Sbjct: 884 G-GRLYRTGDLVRWQPDGCIEYLGRQDHQVKIRGFRIELGEIEARLLAQPGVRQVVVLPH 942
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
S+ ++ +V + + +S + + A L ++L DYM+P +++++++PV NGK+
Sbjct: 943 ET-SAGTRLVGYV-VAQQGAVSCEALRAALAAALPDYMVPAAILQLDSLPVTPNGKL 997
>UniRef50_Q08N46 Cluster: Condensation domain protein; n=3;
Stigmatella aurantiaca DW4/3-1|Rep: Condensation domain
protein - Stigmatella aurantiaca DW4/3-1
Length = 2000
Score = 103 bits (247), Expect = 3e-21
Identities = 63/178 (35%), Positives = 100/178 (56%), Gaps = 6/178 (3%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHNTHP 200
IG P+ N VY+LDE V G GE+CV G + RGY +G+ RFI +P +
Sbjct: 1171 IGRPLKNVQVYVLDEEQNEVPVGVAGELCVGGVGVGRGY-QGRPELTAERFIPHPFSQEA 1229
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LYRTGD ++ G + + GR D QVK+RG R++L+EV+ + P V VV+
Sbjct: 1230 G-ARLYRTGDRARYVEGGELEFLGRMDFQVKLRGFRIELEEVEGVLGKHPGVREVVVVVR 1288
Query: 378 GVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E + ++A+V E+ S++++ + L L +YM+P + +E +P+ + GKV
Sbjct: 1289 EDEGGSRRLVAYVVGKQKESAPSSESLRSYLKEKLPEYMVPSAYVRLEALPLALTGKV 1346
>UniRef50_A0NTU6 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Stappia aggregata IAM 12614|Rep: Putative
non-ribosomal peptide synthetase - Stappia aggregata IAM
12614
Length = 4579
Score = 103 bits (247), Expect = 3e-21
Identities = 61/179 (34%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T PIG P+ N+ VY+LD ++ V +G GE+ + G LARGY D RF+ +P
Sbjct: 4032 TPPIGQPLWNSQVYVLDATLQPVADGVSGELYIGGLGLARGYHGRSDLTSDRFVADPF-- 4089
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A++YRTGD K G +++ GR DSQVKIRGHR++ E++ A++++ + VV+
Sbjct: 4090 AGGGARMYRTGDMVYRQKTGELVFLGRGDSQVKIRGHRIEPGEIEAAITSMTNIAQAVVV 4149
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++A+V A + + + L +L DYM+P + + +P+ NGK+
Sbjct: 4150 DRPDGVRGSSLVAYVVPVEGAELKTDALRSVLLRNLPDYMVPGAFVVLPELPLTPNGKL 4208
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/177 (31%), Positives = 94/177 (53%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG+PI N+ +Y+LD+ ++ V G GE+ + G LARGY D RF+ +P
Sbjct: 2494 PIGLPIWNSGLYVLDQALQPVPNGVAGELYIGGVGLARGYQNLADLTSSRFVADPFAG-- 2551
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+ ++YRTGD + G + + GR+D+QVK+RG R++ E++ + V C+V Y
Sbjct: 2552 DGWRMYRTGDLVYRAEDGNLFFLGRSDAQVKVRGRRIEPGEIERVLLERSDVAQCLVSVY 2611
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ ++A+V + + + L DYM+P I+ + +P L NGK+
Sbjct: 2612 SDRKATSRLVAYVIGQEGSEPDVQELLRYCADRLPDYMVPAQIDLLPYLPRLPNGKI 2668
Score = 93.5 bits (222), Expect = 3e-18
Identities = 56/178 (31%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
VPIG+P N V +LD+ ++ V G GE+ +AG L GY+ G RF+ +P
Sbjct: 1420 VPIGLPRDNCSVRILDDRLQPVGIGMVGELYLAGDCLTLGYLGRTGLTAERFVADPAG-- 1477
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +++YRTGD G++ + GRAD QVKI G R++ QE+++A+ P + C V+
Sbjct: 1478 PAGSRMYRTGDLVRWRSDGLLTFVGRADHQVKINGFRIEPQEIENAIGRQPDIGQCTVVV 1537
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+++A+V + + L+ +L +M+P + +E +P NGK+
Sbjct: 1538 REDRPGEKKLVAYVVGAGAGEPDLERLRERLSETLPAFMVPAHFVLLEHLPFTTNGKL 1595
Score = 92.7 bits (220), Expect = 5e-18
Identities = 61/176 (34%), Positives = 91/176 (51%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG PI + VYLLD+ ++ V +GE GE+ ++G LA GY R K RFI +P P
Sbjct: 364 IGNPIRDTRVYLLDDRLQPVTDGEKGELYISGSGLALGYHRQPDKTAERFIASPFG--PA 421
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A LYRTGD + G + GR+D QVKIRG RV+ EV A+ +P V V+
Sbjct: 422 GALLYRTGDVARRMPDGSYEFLGRSDHQVKIRGVRVEPGEVAAALDRLPDVSRSAVVSNR 481
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++ + A+V A + L +L +P ++ ++ +P+ NGK+
Sbjct: 482 RDNGEVYLAAYVVWGTGADRDGPKLMNALAEALPPAFLPSAIVSLDALPLTPNGKL 537
>UniRef50_UPI00005F995E Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Yersinia
frederiksenii ATCC 33641|Rep: COG1020: Non-ribosomal
peptide synthetase modules and related proteins -
Yersinia frederiksenii ATCC 33641
Length = 1016
Score = 103 bits (246), Expect = 4e-21
Identities = 55/179 (30%), Positives = 98/179 (54%), Gaps = 5/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN--PH 188
++PIG PI ++LD+ + V +G G + + G LARGY + +F++ P
Sbjct: 325 SIPIGQPIDRTLAFILDDRLLPVAQGVIGHLYIGGEGLARGYWNRDELNKEKFVNVTLPG 384
Query: 189 NTHPNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
++ P +LY+TGD GV +Y GR D+QVK+RGHR++L+E++ + V
Sbjct: 385 DSKP--LRLYKTGDLSCQRPDGVFMYHGRMDNQVKLRGHRIELEEIEFQLLNSELVKAAT 442
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIETVPVLVNGK 542
V+ E+++P + AF+ + K ++ +L L +YM+P++ + T+P+ GK
Sbjct: 443 VILVKNENTDPFLAAFIVPHKPDNFKIKALDKKLHQYLPEYMLPRLFVVNTIPLTSTGK 501
>UniRef50_Q9F9L4 Cluster: Micrococcin P1 peptide synthetase; n=1;
Staphylococcus equorum subsp. equorum|Rep: Micrococcin
P1 peptide synthetase - Staphylococcus equorum subsp.
equorum
Length = 915
Score = 103 bits (246), Expect = 4e-21
Identities = 59/179 (32%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++PIG PISN Y+L+E+ + G PGE+C+AG + GY+ + +FI NP
Sbjct: 475 SIPIGKPISNIQAYILNEDNNIMGIGVPGELCIAGVGVTAGYLNRPELTQEKFIDNPFGK 534
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
KLYRTGD + G I+Y GR D QVKIRG+R++L E++ + +++ ++
Sbjct: 535 ----GKLYRTGDLAKWNGDGNIIYIGRIDEQVKIRGYRIELGEIESILRQHTHINDVAIV 590
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + I A++ + + +++ L L DYMIP + +++ +PV NGK+
Sbjct: 591 ARPMVDNELSICAYLV--SDDSLDFGSLKTSLGQKLPDYMIPAYMTQLDELPVTSNGKL 647
>UniRef50_Q70AZ6 Cluster: Non-ribosomal peptide synthetase; n=6;
Actinomycetales|Rep: Non-ribosomal peptide synthetase -
Actinoplanes teichomyceticus
Length = 1865
Score = 103 bits (246), Expect = 4e-21
Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG P++N +Y+LD +R V G GE+ +AG LARGY+ D RF+ P
Sbjct: 780 LPIGRPMTNRRIYILDAFLRPVAPGVAGELYIAGTGLARGYLSRPDLTAERFVACPFLAG 839
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD ++ G +++ GRAD QVKIRG+RV+L EV+ ++ P V VV+
Sbjct: 840 ---ERMYRTGDLARWNRDGEVVFLGRADDQVKIRGYRVELAEVEAVLAAQPGVREAVVVA 896
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ +V ++ + + I ++ L YM+P VI + ++P+ N KV
Sbjct: 897 REDRPGERRLVGYV-VSDAGELDTEQIRQQMARVLPGYMVPVAVIGLVSLPITANSKV 953
>UniRef50_Q0S7I5 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 5592
Score = 103 bits (246), Expect = 4e-21
Identities = 61/179 (34%), Positives = 94/179 (52%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
T +G PI N Y+LD +R V +G PGE+ ++G LARGY+ RF+ +P
Sbjct: 3835 TPTVGTPIWNTSAYVLDAWLRPVPDGVPGELYISGVGLARGYLDRFALTAERFVADPFEE 3894
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
++YRTGD + G + + GR D QVKIRGHRV+L E+ A+ + V V+
Sbjct: 3895 S---VRMYRTGDLVRRREDGNLDFLGRTDDQVKIRGHRVELGEIASALEALDDVRQAAVV 3951
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
I+ + ++ L ++L DYM+P VIE++++P+ VNGK+
Sbjct: 3952 VDSGPGGFKRIVGYAVVSTCQPRDVNKYSQALRATLPDYMVPAAVIEVDSLPMTVNGKL 4010
Score = 95.5 bits (227), Expect = 7e-19
Identities = 59/180 (32%), Positives = 94/180 (52%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHN 191
+ IG P N +Y+LDE++ V G GE+ GF L RGYV G RF+ NP
Sbjct: 788 IATSIGRPNPNTQLYVLDEHLNPVPLGTGGELYAGGFLLGRGYVDAPGLTASRFVANPFA 847
Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
+ ++LYRTGD G + + GRAD+QVKIRG R++L++V+ + + P V + V
Sbjct: 848 N--DGSRLYRTGDLARWAPDGSLDFLGRADNQVKIRGMRLELEDVEAGIVSHPDVRHSAV 905
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ S + A+V ++ + +S L +YM+P + ++ P+ NGK+
Sbjct: 906 VVRETPSGAKYLAAYVVAKQDSVPDVAELRVWASSKLPEYMVPSAFVVLDRFPLTPNGKL 965
Score = 94.3 bits (224), Expect = 2e-18
Identities = 55/179 (30%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNT 194
+VPIG+P SN +Y+LD ++ V G GE+ ++G LARGY+ G RF+ +P +
Sbjct: 2311 SVPIGLPTSNTGLYVLDRYLQPVPAGAAGELYLSGPQLARGYLGRPGLSAERFVADPFSR 2370
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+++YRTGD ++ G + Y GR D QVK+RG R++L E++ ++ P V +
Sbjct: 2371 --TGSRMYRTGDVARVNADGAVEYVGRVDDQVKLRGFRIELGEIEAQMAACPGVRQAAAV 2428
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+++ +V + + ++ A LT++L ++M+P + + PV +GK+
Sbjct: 2429 VRTDRPGQQQLVGYVVGDAD----VDDVRARLTAALPEFMVPVAFVTVPEFPVGPSGKL 2483
Score = 87.0 bits (206), Expect = 2e-16
Identities = 59/182 (32%), Positives = 94/182 (51%), Gaps = 8/182 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG+P N Y+LD+ ++ V G GE+ +AG LARGY+ D RF+ +P
Sbjct: 4889 VPIGIPDPNEQAYVLDDRLQPVPPGVAGELYIAGRGLARGYLGRPDLTSVRFVPSPFGDA 4948
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD G I + GR D QVKIRG R++L E+ A+ + P V V+
Sbjct: 4949 G--TRMYRTGDRARWRADGNIDFLGRVDDQVKIRGFRIELGEIIAALGSHPEVKQSAVVA 5006
Query: 375 YGVESSNPEILAFVTI---NPEARMSAKNIEAELTSSLTDYMIPQVIEI--ETVPVLVNG 539
++ +VT + ++ + + + L DYM+P ++ + E +P+ NG
Sbjct: 5007 -DRSGDIVRLVGYVTSADGHAAGQIDPRAVREHAAARLPDYMVPTLVVVLDEDLPLTPNG 5065
Query: 540 KV 545
K+
Sbjct: 5066 KL 5067
>UniRef50_A7IZW2 Cluster: OciB; n=1; Planktothrix agardhii NIVA-CYA
116|Rep: OciB - Planktothrix agardhii NIVA-CYA 116
Length = 4728
Score = 103 bits (246), Expect = 4e-21
Identities = 65/191 (34%), Positives = 102/191 (53%), Gaps = 16/191 (8%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-- 188
T+PIG I+N +YLLD+N++ V G GE+ + G LA+GY+ + +FI NP
Sbjct: 2932 TIPIGKAIANTQIYLLDKNLQPVPIGVVGELHIGGMGLAKGYLNRPELTQEKFIPNPFEK 2991
Query: 189 ---------NTHPNF-AKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV 335
N N +KLY+TGD L G I Y GR D+QVKIRG R++L E++ +
Sbjct: 2992 DEVIPPTPLNKDGNEPSKLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEALL 3051
Query: 336 STIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEI 512
+ V + V+ + ++A++ PE ++ I L + L DYM+P + +
Sbjct: 3052 NQNEDVQSACVIAREDNPGDKRLVAYLVPQPEIILTIDEIRQFLKAKLPDYMVPNAFVIL 3111
Query: 513 ETVPVLVNGKV 545
E +P+ NGK+
Sbjct: 3112 EALPLTPNGKI 3122
Score = 95.1 bits (226), Expect = 9e-19
Identities = 65/197 (32%), Positives = 102/197 (51%), Gaps = 23/197 (11%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P+SN VY+LD ++ V G GE+ + G LARGY+ + +FI NP +
Sbjct: 784 VPIGRPLSNTQVYILDAFLQPVPVGVAGELHIGGAGLARGYLNRPELTQEKFIPNPFDEE 843
Query: 198 ----PN--------FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVS 338
PN +KLY+TGD L G I Y GR D+QVKIRG R++L E++ +S
Sbjct: 844 GLIPPNPINKGSNESSKLYKTGDLCRYLPDGNIEYLGRIDNQVKIRGFRIELGEIETILS 903
Query: 339 TIPCVDNCVVLCYGVESSNPEILAFV-------TINPEARMSAKNIEAELTSSLTDYMIP 497
V +V+ E+ ++A++ + ++ + L + L +YM+P
Sbjct: 904 QHSAVKTAIVIAREDETEQKRLVAYIVPQEGISNRQEQGLLAVTELRQFLKAQLPEYMVP 963
Query: 498 QV-IEIETVPVLVNGKV 545
+ +E++P+ NGKV
Sbjct: 964 SAFVILESLPLTSNGKV 980
Score = 92.7 bits (220), Expect = 5e-18
Identities = 61/182 (33%), Positives = 99/182 (54%), Gaps = 7/182 (3%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+V IG PI+N Y+LD+N++ G GE+ + G LARGY+ + +FI NP
Sbjct: 1869 SVLIGRPIANTKAYILDQNLQPAPIGVKGELHLCGVRLARGYLNRPELTAEKFIDNPFAA 1928
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVST-IPCVDNCVV 368
P F +LY+TGD L G I GR D+QVKIRG R++L E++ ++ + +CV+
Sbjct: 1929 AP-FNRLYKTGDLARYLPNGSIECFGRIDNQVKIRGFRIELGEIEAILNQHLDVQTSCVI 1987
Query: 369 LCYGVESSNPEILAFVTINP--EARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNG 539
+ + ++A++ I+ E + L +L YM+PQ + +E++P+ N
Sbjct: 1988 IREDLPGQK-YLVAYIVISSHYERIPMISELRQFLAGNLPMYMVPQAFVFLESLPLTTNR 2046
Query: 540 KV 545
KV
Sbjct: 2047 KV 2048
Score = 80.6 bits (190), Expect = 2e-14
Identities = 50/138 (36%), Positives = 74/138 (53%), Gaps = 14/138 (10%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-NT 194
+ IG PI N VY+LD +++ V G PGE+ + G LARGY+ + +FI NP +
Sbjct: 3990 ITIGRPIPNVQVYILDPHLQAVPIGVPGELHIGGAGLARGYLNRPELTAEKFISNPFVSL 4049
Query: 195 HPNF----------AKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVST 341
P +KLY+TGD L G I Y GR D+QVK+RG R++L E++ +
Sbjct: 4050 DPPLTPLDKGGEQPSKLYKTGDLARYLPDGQIEYLGRIDNQVKVRGFRIELGEIEAVLGQ 4109
Query: 342 IPCVDNCVVLCYGVESSN 395
P V +V+ +S+
Sbjct: 4110 HPLVQEAIVIARADHASD 4127
>UniRef50_A4KVL5 Cluster: Non-ribosomal peptide synthetase modules;
n=1; Sinorhizobium meliloti|Rep: Non-ribosomal peptide
synthetase modules - Rhizobium meliloti (Sinorhizobium
meliloti)
Length = 1112
Score = 103 bits (246), Expect = 4e-21
Identities = 60/178 (33%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+PIG +S Y+LD + + G PGE+ V G + RGY+ G ++I +P +
Sbjct: 813 LPIGRAVSQTQAYVLDRSAEPLPYGFPGELYVGGAGVTRGYMNRSGLTAEQYIPDPFSGE 872
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++LYRTGD L G I + GR D+Q+K+ G+R++LQE++ A++ P V V+
Sbjct: 873 PG-SRLYRTGDRASLQSDGNIRFLGRIDNQIKLNGYRIELQEIESALTRHPQVTEAAVVV 931
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ AF T++ +A K + L L YM+P+V I E +PV +GK+
Sbjct: 932 QRSRCGVSRLAAFCTVSGDAATIHKELLLYLRRHLPKYMVPEVFTILEELPVNASGKL 989
>UniRef50_A3KFG6 Cluster: PstD protein; n=1; Actinoplanes
friuliensis|Rep: PstD protein - Actinoplanes friuliensis
Length = 2370
Score = 103 bits (246), Expect = 4e-21
Identities = 67/179 (37%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
T PIG PI+N+ + +LD +R V G PGE+ +AG NLARGY+ RF+ +P
Sbjct: 1832 TAPIGAPIANSAMRVLDPWLRPVPPGVPGELYIAGANLARGYLNRPALTGQRFVPDPLGA 1891
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD D G + Y GR D QVKIRG RV+ EV+ ++T+P V V
Sbjct: 1892 -PG-TRMYRTGDLASWDGDGNLRYLGRTDDQVKIRGFRVEPGEVEAVLTTLPGVTRAAVT 1949
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545
+ ++A+V P +A + ELT L +++P VI ++ +P+ NGK+
Sbjct: 1950 VREDRPGDKRLIAYVV--PAQDTAA--LHRELTGRLPAHLVPAVIVGLDELPLTPNGKL 2004
Score = 89.8 bits (213), Expect = 4e-17
Identities = 59/178 (33%), Positives = 90/178 (50%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG + N + +LD +R V G PGE+ + G + RGY RF +P+
Sbjct: 765 VPIGTALDNTDLRVLDAALRPVPPGVPGELYLGGTGVGRGYHHRPALTAARFAADPYG-E 823
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LYRTGD + GV+ Y GRAD QVKIRG R++ E++ ++ V VV
Sbjct: 824 PG-ARLYRTGDLVRWTETGVLEYLGRADHQVKIRGFRIETGEIEAVLARHDEVAQAVVTV 882
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + + A++ + + A + L YMIP + ++T+P+ NGKV
Sbjct: 883 WEPAPGDKRLAAYLVGARGGTLDTAGVRAHAEAVLPGYMIPAAFVVLDTLPLTGNGKV 940
>UniRef50_A0ZF82 Cluster: Non-ribosomal peptide synthase; n=2;
Nostocaceae|Rep: Non-ribosomal peptide synthase -
Nodularia spumigena CCY 9414
Length = 1394
Score = 103 bits (246), Expect = 4e-21
Identities = 67/180 (37%), Positives = 101/180 (56%), Gaps = 7/180 (3%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG P N +Y+LD + + + G PGE+C+AG LARGY+ + +FI
Sbjct: 847 PIGKPWPNIQIYILDAHHQPLPPGIPGELCIAGVGLARGYLNRPELTAEKFIE--VELFG 904
Query: 201 NFAKLYRTGD---FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
++Y+TGD +GI G + Y GR D QVK+RG R++L E++ + P V VV+
Sbjct: 905 KVKRIYKTGDLARWGI--DGNLEYLGRIDEQVKLRGFRIELGEIESQLLQHPSVKEAVVI 962
Query: 372 CYGVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
Y E SN ++A+VT I + +N L S L DYMIP Q++ ++ +P+ NGK+
Sbjct: 963 LYKTE-SNQSLIAYVTGITHDLCPELRN---HLKSRLPDYMIPAQIMVLDKLPLTPNGKI 1018
>UniRef50_Q8YTR5 Cluster: Peptide synthetase; n=7; Cyanobacteria|Rep:
Peptide synthetase - Anabaena sp. (strain PCC 7120)
Length = 2588
Score = 102 bits (245), Expect = 5e-21
Identities = 70/192 (36%), Positives = 105/192 (54%), Gaps = 17/192 (8%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIH----- 179
TVPIG PI+N ++Y+LD++++ V G PGE+ + G +ARGY+ + RFI
Sbjct: 772 TVPIGRPIANTHIYILDQHLQPVPIGVPGELYIGGAGVARGYLNRPELTAERFISYSDLG 831
Query: 180 -------NPHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV 335
PH P LY+TGD L G I Y GR D+QVKIRG R++L E++ +
Sbjct: 832 SIGYLTPMPHAPCPIPHALYKTGDRARYLRDGTIEYLGRLDNQVKIRGFRIELGEIETVL 891
Query: 336 STIPCVDNCVVLCYGVESSNPEILAF-VTINPEARMSAKNIEAELTSSLTDYMIP-QVIE 509
S V +V+ + + ++A+ V+ NPE ++ L +L DYMIP Q I
Sbjct: 892 SQHSEVQAAIVVVTEDTTGDKRLVAYIVSENPE----ITDLRQYLAKNLPDYMIPSQFIT 947
Query: 510 IETVPVLVNGKV 545
++ +P+ NGKV
Sbjct: 948 LDALPLTPNGKV 959
Score = 102 bits (244), Expect = 6e-21
Identities = 69/185 (37%), Positives = 99/185 (53%), Gaps = 10/185 (5%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNT 194
TVPIG PI+N VY+LD ++ + G PGE+ +AG LARGY+ +FI+ T
Sbjct: 1830 TVPIGRPINNTQVYILDNHLNPLPVGVPGELYIAGDGLARGYLNQPTLTAEKFINWGLGT 1889
Query: 195 ------HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353
+ LY+TGD L G I Y GR D+QVKIRG R++L E++ ++ P V
Sbjct: 1890 GDWGLGTTTLSTLYKTGDRARYLADGNIEYLGRLDNQVKIRGFRIELGEIEAVLNQHPAV 1949
Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVL 530
CVV + I F+ ++ + N+ L L DY+IP + +ET+P+
Sbjct: 1950 KECVV----IAREKQLIAYFIALD----NTPDNLREFLQQRLPDYLIPHFFVALETLPLT 2001
Query: 531 VNGKV 545
VNGKV
Sbjct: 2002 VNGKV 2006
>UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7;
Pseudomonas|Rep: Amino acid adenylation - Pseudomonas
fluorescens (strain PfO-1)
Length = 5422
Score = 102 bits (245), Expect = 5e-21
Identities = 60/178 (33%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+PIG P+SN +Y+LDE ++ + G GE+ + G +ARGY+ RF+ +P +
Sbjct: 862 LPIGRPVSNTRLYILDEQLQPLPLGVAGELYIGGVQVARGYLNLASLTAERFLDDPFSDQ 921
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
PN A+LYRTGD G + Y GR D QVK+RG R++L E+ ++ + V VL
Sbjct: 922 PN-ARLYRTGDLCRYRADGNLEYLGRNDDQVKVRGLRIELGEIQTRLTQLATVLAAEVLV 980
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ +P ++A+ T P + + + L L DYM+P + + +P+ NGK+
Sbjct: 981 REDVAGDPRLVAYYTGGP---LEIGELRSHLLEQLPDYMVPTAFVHLAAMPLSPNGKL 1035
Score = 101 bits (242), Expect = 1e-20
Identities = 64/177 (36%), Positives = 96/177 (54%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI+N +Y+LD + V +G GE+ + G +ARGY+ + RF+++P P
Sbjct: 5155 PIGKPIANTRLYILDAQQQPVPQGVVGELYIGGVQVARGYLNRPELSAERFLNDPFK--P 5212
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
N ++YRTGD L G I Y GR D QVKIRG R++L E+ ++ I V VVL
Sbjct: 5213 N-GRMYRTGDVARYLADGNIEYLGRNDDQVKIRGLRIELGEIQSRLTDISGVQEAVVLAR 5271
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+ T AR+ + L L DYM+P V + + +P+ NGK+
Sbjct: 5272 EDVPGDKRLVAYYT---GARLVIDVLRGHLLEHLPDYMVPAVFVHLGALPLSPNGKL 5325
Score = 98.7 bits (235), Expect = 8e-20
Identities = 61/179 (34%), Positives = 97/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG PISN VY+LD + V G GE+ + G +A GY+ D +F+ +P +
Sbjct: 1931 SVPIGGPISNTQVYVLDARQQPVPMGVTGELYIGGQGVALGYLSRPDLTAEKFLQDPFSE 1990
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A LYRTGD L G + GR D QVKIRG R++L E+++ + V +VL
Sbjct: 1991 QPG-ALLYRTGDLARWLAPGQLECIGRNDDQVKIRGFRIELGEIENRLLNCDGVKEAIVL 2049
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+ T E + + ++ +L + L +YM+P ++++ +P+ NGKV
Sbjct: 2050 ARQDGQEPLRLVAYFT--AEKGVDSASLREQLQARLPEYMVPSAWVQLDALPLNNNGKV 2106
Score = 98.3 bits (234), Expect = 1e-19
Identities = 64/176 (36%), Positives = 98/176 (55%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG P++N +YLLD+ R V G GE+ VAG +ARGY+ D RF+ +P + P
Sbjct: 3001 IGRPMANARIYLLDDQQRPVPVGVTGEMYVAGAGVARGYLNRPDLTAERFLTDPFSDQPQ 3060
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD L G I Y GR D QVK+RG RV+L E++ A+++ P V + V L
Sbjct: 3061 -ARMYRTGDLARWLADGNIEYLGRNDDQVKLRGVRVELGEIEAALASHPAVQDAVALV-- 3117
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++L + T A + A + L + L +IP + ++ +P+ NGK+
Sbjct: 3118 ---RDGQLLVWFTERAPADIEA--LRNHLQTRLPQALIPAAYVRLDALPLTANGKL 3168
Score = 75.8 bits (178), Expect = 6e-13
Identities = 56/179 (31%), Positives = 92/179 (51%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI+N +Y+LD R V G G++ + G +ARGY+ RF +P
Sbjct: 4076 LPIGRPINNTRLYVLDAAKRPVPMGVIGQLFIGGAGVARGYLGLPQLMAERFTPSPFVAG 4135
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LY TGD G + + GR D QVK+RG R++ E++ + + P + VVL
Sbjct: 4136 D---RLYATGDLVRYRADGQLEFIGRNDFQVKLRGLRLEPGEIEAQLLSHPALREAVVLV 4192
Query: 375 YGVESSNPEILAFVTINPEA-RMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++A+ T + EA + + + L + L DYM+P + ++++P+ NGKV
Sbjct: 4193 -----REERLVAYFTWHAEAGQPGIEALREHLLARLPDYMVPSAFVALDSLPLSPNGKV 4246
>UniRef50_Q9K5M1 Cluster: Peptide synthetase; n=8; Bacteria|Rep:
Peptide synthetase - Anabaena circinalis 90
Length = 5060
Score = 102 bits (245), Expect = 5e-21
Identities = 63/189 (33%), Positives = 104/189 (55%), Gaps = 16/189 (8%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI+N +Y+LDE ++ V G PGE+ + G LARGY+ + +FI NP +
Sbjct: 782 PIGRPIANAQIYILDEYLQLVPVGVPGELHIGGAGLARGYLNRPELTQEKFIPNPFDNSK 841
Query: 201 -----------NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTI 344
+KLY+TGD L G I Y GR D+QVKIRG R++L E++ +S +
Sbjct: 842 FKIPYRNAKDVQNSKLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAVLSQL 901
Query: 345 PCVD-NCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIET 518
V +CV++ + + + ++A++ E + + L + L +YM+P + +E+
Sbjct: 902 GDVQASCVIVREDI-TGDKRLVAYIVPQKEVTPTVTELRQFLKAKLPEYMVPNAFVILES 960
Query: 519 VPVLVNGKV 545
+P+ NGK+
Sbjct: 961 LPLTPNGKI 969
Score = 90.2 bits (214), Expect = 3e-17
Identities = 51/119 (42%), Positives = 71/119 (59%), Gaps = 3/119 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+P+ PI+N VY+LD ++ V G PGE+ +AG +ARGY+ + +FI NP
Sbjct: 4354 LPLVGPIANVQVYILDSQLQPVPIGVPGELHIAGVGVARGYLNRPELTQEKFISNPFGP- 4412
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+KLY+TGD G L G I Y GR D+QVKIRG R++L E++ S P V VV+
Sbjct: 4413 ---SKLYKTGDLGRYLADGTIEYLGRIDNQVKIRGFRIELGEIEAVASQHPLVQESVVI 4468
Score = 88.2 bits (209), Expect = 1e-16
Identities = 58/164 (35%), Positives = 88/164 (53%), Gaps = 9/164 (5%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI + VY+LDE+++ V G GE+ V G + RGY+ + RFI NP N +
Sbjct: 2945 IGRPIGDLQVYVLDEHLQPVPIGVAGEMYVGGAGVTRGYLNRAELTAQRFISNPFNGNSE 3004
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
LY++GD L G + Y GR D+QVKIRG R++L E++ A+S + V VV+
Sbjct: 3005 -QLLYKSGDLARYLPNGELEYLGRIDNQVKIRGFRIELGEIEAALSQLREVREVVVVARS 3063
Query: 381 VESSNPEILAFVTINPEARMSAKNIE------AELTSSLTDYMI 494
+ N ++A+V + S+K E EL S+ +Y +
Sbjct: 3064 DQPDNKRLVAYVVPQQKNLESSKKPEKLSTDKVELWPSIAEYYV 3107
Score = 81.4 bits (192), Expect = 1e-14
Identities = 60/191 (31%), Positives = 98/191 (51%), Gaps = 16/191 (8%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP--- 185
+V IG PI+N Y+LD +++ V G GE+ + G LARGY+ + +FI NP
Sbjct: 1861 SVLIGRPIANTQAYILDRHLQPVPVGVKGELHLCGVRLARGYLNRPELTEEKFIPNPFSG 1920
Query: 186 --------HNTHP-NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV 335
++ P ++LY+TGD L G I GR D+QVKIRG R++L E++ +
Sbjct: 1921 SRGAEILANSQSPVPSSRLYKTGDLARYLPDGNIECFGRIDNQVKIRGFRIELGEIEAVL 1980
Query: 336 STIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEI 512
+ V V+ + ++A+V PE + + L+ +L YM+PQ + +
Sbjct: 1981 NQYIDVQTSCVIIREDTPGDKYLVAYVVPYPEKIPTISELRQFLSRNLPLYMVPQAFVFL 2040
Query: 513 ETVPVLVNGKV 545
+ +P+ N KV
Sbjct: 2041 DFLPLTPNRKV 2051
>UniRef50_Q6HXY8 Cluster: AMP-binding enzyme; n=10; Bacillus cereus
group|Rep: AMP-binding enzyme - Bacillus anthracis
Length = 2345
Score = 102 bits (245), Expect = 5e-21
Identities = 56/177 (31%), Positives = 100/177 (56%), Gaps = 2/177 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
++P G+P++N Y+L+ + G G++ + G LA+GY+ + + + +HP
Sbjct: 1604 SIPYGMPLANQTYYVLNYEKKMCPVGVIGDLYIGGVGLAKGYLNAE---KKTNEAFVSHP 1660
Query: 201 NFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+F +Y+TGD G + +G I + GR D QVKI+G+RV+L+E+ H + T V++ VV+
Sbjct: 1661 DFGLIYKTGDCGKMHSEGYIEFLGRQDYQVKIQGYRVELEEISHCLLTYKQVEHAVVIDQ 1720
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E+ ++A+V E +S + L L DYMIP + ++ +P+ NGK+
Sbjct: 1721 TDENGIKFLVAYVV--TEQNISTTELRKHLRDHLPDYMIPSYFVYLDQLPLTPNGKL 1775
Score = 91.5 bits (217), Expect = 1e-17
Identities = 62/181 (34%), Positives = 103/181 (56%), Gaps = 7/181 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHNT 194
V IG P N + Y+L++ + G PGE+C+AG +ARGY+ GK +F+ +P
Sbjct: 575 VTIGKPNPNYHSYILNKYGQLKPFGIPGELCIAGVAVARGYL-GKSKLTDEKFVPSPFAA 633
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+Y TGD L G + Y GR D QVKIRG+R++L+E++ + P ++ +V+
Sbjct: 634 GE---MMYHTGDLVRWLPNGELEYLGRMDHQVKIRGYRIELREIETQLREYPEINQVIVV 690
Query: 372 --CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542
YG N ++LA ++ + ++S I L+ L ++MIP+ +I++E +P+ NGK
Sbjct: 691 DQVYG----NRKLLAAYYVS-DNKVSFGEIRKYLSDKLPEFMIPEKMIQVEEIPLNPNGK 745
Query: 543 V 545
V
Sbjct: 746 V 746
>UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces
filamentosus|Rep: Peptide synthetase 2 - Streptomyces
filamentosus (Streptomyces roseosporus)
Length = 7338
Score = 102 bits (245), Expect = 5e-21
Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200
P+G P+ N VY+LD+ +R V G GE+ VAG LARGY+ G RF+ P
Sbjct: 2897 PMGRPLRNTCVYVLDDGLRVVPVGVVGELYVAGVGLARGYLGRVGLTAERFVACPFGARG 2956
Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD G + + GRAD QVK+RG RV+L EV+ AV+ P V VV+
Sbjct: 2957 E--RMYRTGDLVRWRVDGTLEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVVVVR 3014
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+VT +S+ + A + L YM+P V+ ++ +P+ NGKV
Sbjct: 3015 EDRPGDHRLVAYVTGVDTGGLSSAVMRA-VAERLPAYMVPSAVVVLDEIPLTPNGKV 3070
Score = 100 bits (240), Expect = 2e-20
Identities = 69/181 (38%), Positives = 98/181 (54%), Gaps = 6/181 (3%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHN 191
TVPIG PI N Y+LD +R V G PGE+ +AG LARGY G+ RF+ P
Sbjct: 6556 TVPIGRPIWNIRTYVLDAALRPVPPGVPGELYLAGAGLARGY-HGRPALTAERFVACPFG 6614
Query: 192 THPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
P ++YRTGD G + + GRAD QVK+RG RV+L EV+ AV+ P V VV
Sbjct: 6615 V-PG-ERMYRTGDLVRWRVDGTLEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVV 6672
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKN-IEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542
+ + ++A+VT+ ++ I + L YM+P V+ ++ +P+ NGK
Sbjct: 6673 VVREDRPGDHRLVAYVTVGGVGGDGLRSAISGLVAERLPAYMVPSAVVVLDEIPLTPNGK 6732
Query: 543 V 545
V
Sbjct: 6733 V 6733
Score = 98.3 bits (234), Expect = 1e-19
Identities = 61/176 (34%), Positives = 94/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG P+ N Y+LD +R V EG GE+ +AG LARGY G RF+ P P
Sbjct: 778 IGHPLDNTAAYILDGFLRPVPEGVAGELYLAGTQLARGYAGRPGLTAERFVACPFGA-PG 836
Query: 204 FAKLYRTGDFGILDKG-VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++YRTGD G V+ Y GR D Q+K+RG R++ E++ A++ P V VVL +
Sbjct: 837 -ERMYRTGDLVRRSPGGVVEYLGRVDDQIKLRGFRIEPAEIELALAGHPAVAQNVVLLHR 895
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V P + + + L + L YM+P + ++T+P+ NGK+
Sbjct: 896 SATGEARLVAYVV--PGTPVDPRELTGHLAARLPAYMVPSAFVLLDTLPLTPNGKL 949
Score = 98.3 bits (234), Expect = 1e-19
Identities = 66/178 (37%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
VPIG P + +++LD +R V G GE+ VAG LARGY+ G RF+ P
Sbjct: 1846 VPIGRPFAGQRMFVLDAALRVVPVGVVGELYVAGVGLARGYLGRAGLTAERFVACPFGA- 1904
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD G + + GRAD QVK+RG RV+L EV+ AV+ P V VV+
Sbjct: 1905 PG-ERMYRTGDLVRWRVDGALEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVVVV 1963
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+VT +S+ + A + L YM+P V+ ++ +P+ NGKV
Sbjct: 1964 REDRPGDHRLVAYVTGVDTGGLSSAVMRA-VAERLPAYMVPSAVVVLDEIPLTPNGKV 2020
Score = 97.1 bits (231), Expect = 2e-19
Identities = 66/176 (37%), Positives = 95/176 (53%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHPN 203
IG PI N VY+LD + V G GE+ +AG LARGY+ G RF+ P P
Sbjct: 5501 IGTPILNTRVYVLDAALCVVPPGVAGELYIAGDGLARGYLGRAGLTAERFVACPFGA-PG 5559
Query: 204 FAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
++YRTGD G + + GRAD QVK+RG RV+L EV+ AV+ P V VV+
Sbjct: 5560 -ERMYRTGDLVRWRVDGALEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVVVVRE 5618
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+VT +S+ + A + L YM+P V+ ++ +P+ NGKV
Sbjct: 5619 DRPGDHRLVAYVTGVDTGGLSSAVMRA-VAERLPAYMVPSAVVVLDEIPLTPNGKV 5673
Score = 96.3 bits (229), Expect = 4e-19
Identities = 65/179 (36%), Positives = 95/179 (53%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P + +++LD +R V G GE+ VAG LARGY+ G RF+ P
Sbjct: 4437 VPIGRPFAGQRMFVLDAALRVVPVGVVGELYVAGVGLARGYLGRVGLTAERFVACPFGV- 4495
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD G + + GRAD QVK+RG RV+L EV+ AV+ P V VV+
Sbjct: 4496 PG-ERMYRTGDLVRWRVDGALEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVVVV 4554
Query: 375 YGVESSNPEILAFVTINPEARMSAKN-IEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+VT ++ I + L YM+P V+ ++ +P+ NGKV
Sbjct: 4555 REDRPGDHRLVAYVTAGGVGGDGLRSAISGLVAERLPAYMVPSAVVVLDEIPLTPNGKV 4613
>UniRef50_Q0YRD8 Cluster: Amino acid adenylation; n=2; cellular
organisms|Rep: Amino acid adenylation - Chlorobium
ferrooxidans DSM 13031
Length = 1550
Score = 102 bits (245), Expect = 5e-21
Identities = 61/178 (34%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI+N +YLLD N + V G GE+ + G LA GY+ + +FI +P ++
Sbjct: 775 LPIGRPIANTRLYLLDRNRQPVPTGIAGELYIGGVGLASGYLNRPELTAEKFIPDPFSSR 834
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +LY+TGD G + + GR D Q+KIRG R++ E++ A++ IP + + +V
Sbjct: 835 PG-ERLYKTGDLVRYRTDGNLEFLGRLDHQLKIRGFRIEPGEIESALTAIPSIHSALVDA 893
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
P + A++ + S + A+L +L +YMIP I +E +P+ VNGK+
Sbjct: 894 RNDAYGQPALAAWL-VAAGTPPSIAGLRADLGRTLPEYMIPTSFIFLEAMPLTVNGKI 950
>UniRef50_A0V6U0 Cluster: Amino acid adenylation domain; n=1; Delftia
acidovorans SPH-1|Rep: Amino acid adenylation domain -
Delftia acidovorans SPH-1
Length = 2149
Score = 102 bits (245), Expect = 5e-21
Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200
P+GV I + +Y+LD ++ + +G GE+ VAG LARGY+ G RFI NP
Sbjct: 750 PVGVAIPDLGLYVLDGSLNLLPQGVAGELYVAGEGLARGYLNRAGLSAERFIANPFTQAG 809
Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+ +LYRTGD +G + Y GRAD QVKIRG R++L EV + P V VVL
Sbjct: 810 D--RLYRTGDLVRWSAQGELEYLGRADQQVKIRGFRIELGEVQSQLLAQPEVREAVVLA- 866
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++A+V++ S ++ L +L DYM+P ++ +E +P+ NGKV
Sbjct: 867 ---KEGARLIAYVSLRDAVEES--QLKQRLGQALPDYMVPSAIVVLEALPLTANGKV 918
Score = 98.3 bits (234), Expect = 1e-19
Identities = 69/190 (36%), Positives = 102/190 (53%), Gaps = 18/190 (9%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
+G I+ + +LDE +RCV +G GE+ + G LARGY + G RF+ +P P
Sbjct: 1833 LGQAIAATRLLVLDEGLRCVPQGVAGELFIGGQGLARGYWQRPGLSAERFVADPF-AGPG 1891
Query: 204 FA--KLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A +LYRTGD + G + Y GR D QVKIRGHR++L EV+ A+ P V VV
Sbjct: 1892 AAGERLYRTGDLVRRNADGALEYLGRLDHQVKIRGHRIELGEVEAALLAQPEVREAVVTA 1951
Query: 375 YGVESSNPEILAFVTINPEARMS------------AKNIEAELTSSLTDYMIPQ-VIEIE 515
G S+ ++A V+++ S A + A L S L DYM+P ++ ++
Sbjct: 1952 AG-SGSDTRLVAHVSLHASLHASLHAPLHAGPPLDAAALRARLASGLPDYMLPSAIVVLD 2010
Query: 516 TVPVLVNGKV 545
T+P+ +GKV
Sbjct: 2011 TLPLNNSGKV 2020
>UniRef50_Q2SW14 Cluster: Peptide synthetase, putative; n=1;
Burkholderia thailandensis E264|Rep: Peptide synthetase,
putative - Burkholderia thailandensis (strain E264 / ATCC
700388 / DSM 13276 /CIP 106301)
Length = 3650
Score = 102 bits (244), Expect = 6e-21
Identities = 59/177 (33%), Positives = 97/177 (54%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI+N +Y+LD + + V G GE+ +AG +ARGY+ + RF+ + P
Sbjct: 837 PIGRPIANTRIYILDSHGQPVPIGVAGEIHIAGAGVARGYLNRPELTAERFVSDSFAAAP 896
Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
N A++YRTGD G L G I Y GR D QVKIRG R++L E++ ++ V + VV+
Sbjct: 897 N-ARMYRTGDLGRWLPDGTIEYLGRNDFQVKIRGLRIELGEIEARLARCDGVRDAVVIAR 955
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V + + +L L ++M+P + ++ +P+ NGK+
Sbjct: 956 EDTPGDKRLVAYVLPQSGVALVPAELRRQLAGQLAEHMLPSAFVMLDALPLTPNGKL 1012
Score = 95.5 bits (227), Expect = 7e-19
Identities = 59/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VP G + +Y+L ++R + G PG++ +AG +ARGY+ D +RF+ +PH
Sbjct: 1912 VPYGRHLPGQRLYVLSSSLRPLPIGVPGDLWIAGAGVARGYLGQPDLTAYRFVADPHV-- 1969
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD +L G + + GR D QVKIRG R+++ E++ A+ P V+ V
Sbjct: 1970 PG-ERMYRTGDRARVLADGNLEFLGRVDDQVKIRGFRIEIGEIEAALGAAPGVERGVATI 2028
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
I A+V A + I L L YM+P ++ I++VP+ NGK+
Sbjct: 2029 V-EHHGRQTIAAYVVARANAVLDHAEIRDALARRLPPYMLPASIVSIDSVPLTRNGKI 2085
Score = 87.8 bits (208), Expect = 1e-16
Identities = 60/178 (33%), Positives = 92/178 (51%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
V IG P +YLLD + R V G GE+ VAG +A GY+ + RF+ +P+
Sbjct: 3353 VTIGRPFPGQRIYLLDRHGRLVPPGAVGEIHVAGEGIAAGYLGAQALTAQRFVADPY--R 3410
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YR+GD G L G + GRAD QVKIRG+R++L E++ A+S++ + V
Sbjct: 3411 PG-ERMYRSGDLGRFLPGGRMESLGRADRQVKIRGYRIELGEIECALSSLEGIGGAVADV 3469
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
S + +V A M A+ + L L D M+P +I ++ + NGK+
Sbjct: 3470 REGASGRQLVAWYVA---AADMDAQRVRTALKQRLPDSMMPSALIRVDGFALTANGKI 3524
>UniRef50_Q7BQ70 Cluster: Putative peptide synthetase/polyketide
synthase; n=1; Bacillus cereus|Rep: Putative peptide
synthetase/polyketide synthase - Bacillus cereus
Length = 2562
Score = 102 bits (244), Expect = 6e-21
Identities = 65/185 (35%), Positives = 101/185 (54%), Gaps = 4/185 (2%)
Frame = +3
Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFI 176
+MH L+ IGVP+ Y+ D++M +G GE+ V G +ARGY+ + RFI
Sbjct: 749 EMHSNLSA-IGVPLPTYSCYVFDKHMNPTPKGMQGELYVGGHGVARGYLNRPELNSERFI 807
Query: 177 HNPHNTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353
NP+N P+ +LYR+GD IL+ G + Y GR+D QVKIRG+R++ E++H + V
Sbjct: 808 QNPYN--PS-ERLYRSGDLVRILENGEMEYIGRSDHQVKIRGYRIETGEIEHHLQQHADV 864
Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVL 530
VVL E+ A++ + + +S + LT + YMIP + + +P+
Sbjct: 865 KEAVVLSIAF-GEEQELCAYILTDQD--ISQNELRYYLTDKIPSYMIPMYFVLLSEMPLT 921
Query: 531 VNGKV 545
NGKV
Sbjct: 922 TNGKV 926
>UniRef50_Q70JX4 Cluster: FenD protein; n=18; Bacillus|Rep: FenD
protein - Bacillus amyloliquefaciens
Length = 3605
Score = 102 bits (244), Expect = 6e-21
Identities = 62/177 (35%), Positives = 96/177 (54%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200
PIG PI +N +Y+L +N + G GE+ ++G N RGYV +F+ +P T
Sbjct: 791 PIGKPIHHNKMYILSKNRQLQPLGIAGELYISGANTGRGYVNNPALTEEKFLPDPFRTD- 849
Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A +YRTGD L G I Y GR D QVKIRG+R++ +E++ ++ V VL
Sbjct: 850 --AVMYRTGDLARLRADGQIEYIGRTDDQVKIRGYRIEPKEIETVLANHHAVKEAAVLIQ 907
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
ES E+ A+ +++ S + ++L L DYMIP + ++++P+ NGKV
Sbjct: 908 TNESGENELCAYCSVSQATDPS--QLRSDLAKELPDYMIPVKWAFVDSIPLTANGKV 962
Score = 98.3 bits (234), Expect = 1e-19
Identities = 58/178 (32%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNTH 197
+ IG PI +++VY+L+ + G GE+C++G LARGY + + F+ +P +
Sbjct: 2849 ITIGRPIEHSHVYILNGD-HPQPIGVTGELCISGSGLARGYRNLPKQTAQAFVQDPFQKN 2907
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD L G + Y GR D QVKIRG+RV+L+E++ A++ I V V
Sbjct: 2908 ---RRMYRTGDLAKWLPDGTLQYIGRIDEQVKIRGYRVELKEIESALTGIKGVKEAAVTA 2964
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ + E+ A++ E ++ ++ L + + YM+P E +E +PV NGK+
Sbjct: 2965 HTASAGQTELCAYIV--TEEGTESETVQQALRNEMPAYMVPAFFETLEALPVTPNGKL 3020
Score = 86.6 bits (205), Expect = 3e-16
Identities = 58/181 (32%), Positives = 100/181 (55%), Gaps = 4/181 (2%)
Frame = +3
Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH 188
F VPIG+ N +Y+L++ R + G GE+ +AG +ARGY+ + RF+ +P
Sbjct: 1822 FHNVPIGISGHNMRLYILNQKKRLLPPGCIGELYIAGTGVARGYLNRPELTEERFLDDPF 1881
Query: 189 NTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
+P ++Y+TGD ++G++ + GR+D QVK+RG+R++ E++ A+ I +
Sbjct: 1882 --YPG-ERMYQTGDIARWTEEGLVEWLGRSDGQVKVRGYRIEPGEIEAAIRRIDGIREAA 1938
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGK 542
V E + A++ E R S ++ AEL + L YM+P Q I++ PV +GK
Sbjct: 1939 VTA-RTEHGETALYAYI----EGRES-DDVRAELATRLPAYMMPAQFIKMSEWPVTPSGK 1992
Query: 543 V 545
+
Sbjct: 1993 L 1993
>UniRef50_Q0YRE2 Cluster: Amino acid adenylation; n=1; Chlorobium
ferrooxidans DSM 13031|Rep: Amino acid adenylation -
Chlorobium ferrooxidans DSM 13031
Length = 1727
Score = 102 bits (244), Expect = 6e-21
Identities = 64/176 (36%), Positives = 97/176 (55%), Gaps = 2/176 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
+VPIG PI+ +YLLD+ MR G GE+ AG LA GY G+D + H +P
Sbjct: 493 SVPIGTPIAGTRIYLLDDAMRPCGAGVIGELYAAGEGLAIGYAAGEDLDARVFVTHPDNP 552
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+LYRTGD + G++ + GR D Q+K+RGHRV+L ++ +S V++ + +
Sbjct: 553 E-ERLYRTGDLARFREDGLLEFCGRRDGQIKLRGHRVELPAIEAVLSGCKGVNDSLAMVN 611
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGK 542
G + E++AFV+ + M+ +N AE L YM+P + I E P+ NGK
Sbjct: 612 G-KGEGMELVAFVSSSQPDEMAWRNRIAE---RLPLYMMPARFITFEHFPLNANGK 663
Score = 83.8 bits (198), Expect = 2e-15
Identities = 59/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V IG PI+N +Y+LD + G PGE+ + G +ARGY+ + RFI +P
Sbjct: 1458 VSIGRPIANTSLYILDGRHHPLPVGIPGEIAIGGVQVARGYLNRPELTAERFIADPFT-- 1515
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+ +LY TGD G G I Y GR+D QVKIRG R++ E++HA+ T + VV+
Sbjct: 1516 PD-GRLYLTGDRGRWQPDGSIAYLGRSDWQVKIRGQRIEPGEIEHALETHTDIVRAVVVP 1574
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + E+ A++ + + + L L + MIP + I + +P ++GK+
Sbjct: 1575 VSNQGLD-ELHAWILC--DGSVEQGEVRRFLREQLPESMIPARFILLRELPYTLSGKL 1629
>UniRef50_Q0LKI8 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1127
Score = 102 bits (244), Expect = 6e-21
Identities = 56/138 (40%), Positives = 80/138 (57%), Gaps = 3/138 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
T PIG P++N VYLLD+ + V G GE+ V G +ARGY++ RFI N ++
Sbjct: 807 TPPIGRPLANLQVYLLDQQQQIVPVGVIGEIYVGGVGVARGYLKRPALTAERFIPNQFSS 866
Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +LYRTGD G G I + GR D Q+K+RGHR++L E+ ++ P V+ VVL
Sbjct: 867 TPG-QRLYRTGDLGRYRVDGQIEFVGRIDQQIKLRGHRIELGEISSLLNAHPAVEQSVVL 925
Query: 372 CYGVESSNPEILAFVTIN 425
+ SS ++A+V N
Sbjct: 926 VHDHASSTARLIAYVVAN 943
>UniRef50_A3IZB3 Cluster: Amino acid adenylation; n=2;
Chroococcales|Rep: Amino acid adenylation - Cyanothece
sp. CCY 0110
Length = 1178
Score = 102 bits (244), Expect = 6e-21
Identities = 64/187 (34%), Positives = 99/187 (52%), Gaps = 7/187 (3%)
Frame = +3
Query: 6 MHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIH 179
+ ++ T+PIG P+ N Y+LD V G GE+ + G LA GY+ + +FI+
Sbjct: 538 IELYRTIPIGRPLPNRKTYILDTQKNPVPIGVVGELYIGGEGLACGYLNQFELTQEKFIN 597
Query: 180 NPHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVD 356
NP +LY+TGD L G I + GR D+QVK+RG R++L E++ ++ V
Sbjct: 598 NPFE----IGQLYKTGDLARYLTDGNIEFLGRIDNQVKLRGFRIELGEIETILTKYSYVR 653
Query: 357 NCVVLCYGVESSNPEILAFVTINPEARMSAK---NIEAELTSSLTDYMIPQV-IEIETVP 524
++ SN ++A++ +NP S K I+ L L +YMIP V I +ET P
Sbjct: 654 EAKIMIREDNYSNQRLVAYIILNPCQTSSLKISQQIKEYLQEKLPNYMIPSVFIILETFP 713
Query: 525 VLVNGKV 545
+ NGK+
Sbjct: 714 LTPNGKI 720
>UniRef50_A0UXC9 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain - Clostridium
cellulolyticum H10
Length = 3695
Score = 102 bits (244), Expect = 6e-21
Identities = 63/178 (35%), Positives = 102/178 (57%), Gaps = 4/178 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+ IG PI+N VY++ E+ G PGE+C++G L+RGY+ + +F+ NP+
Sbjct: 2316 TIDIGKPIANTQVYIVSESGNLQPIGIPGELCISGDGLSRGYINRPELTLEKFLENPY-- 2373
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P K+YRTGDF L G I Y R D QVK+RG+R++L E++ + V VV
Sbjct: 2374 MPG-KKMYRTGDFVKWLPDGNIEYIRRIDHQVKLRGYRIELGEIEELLLKYSGVREAVVD 2432
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGK 542
G +S + ++ A+VT + + ++ ++ L + L YMIP ++ +E +P+ NGK
Sbjct: 2433 VKGEDSESRKLGAYVTADRD--LTEVELKKYLENELPQYMIPTYIMVLEELPLTPNGK 2488
Score = 92.3 bits (219), Expect = 7e-18
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 3/177 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
+PIG PISNN V +LD + G PG++ ++G N+ RGY + ++ R + + +
Sbjct: 3385 IPIGKPISNNKVLILDSCKKMCPIGIPGDIYISGLNVTRGYYKDEEKTREVFTLYGEKGS 3444
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHA-VSTIPCVDNCVVLCY 377
+YRTGD G L G I Y GR D +K+RG+R+++ E+++ + + VV
Sbjct: 3445 I--IYRTGDVGRYLSDGTIEYLGRKDGMIKVRGYRIEIGEIENVLLQNEEIIQAAVVAKK 3502
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E+S +++ + T E + + + L L DYMIP Q I +E + + NGK+
Sbjct: 3503 SGETS--KLICYYTAPRE--HTYEELRGCLEKKLPDYMIPAQFIWLEKMILTPNGKI 3555
>UniRef50_A0JZK7 Cluster: Amino acid adenylation domain; n=1;
Arthrobacter sp. FB24|Rep: Amino acid adenylation domain
- Arthrobacter sp. (strain FB24)
Length = 3524
Score = 102 bits (244), Expect = 6e-21
Identities = 61/178 (34%), Positives = 97/178 (54%), Gaps = 6/178 (3%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
+G ++N+ Y+LD + V GE+ VAG NLARGYV G RF+ +P P+
Sbjct: 789 LGDSVANSRHYILDSGLNPVPVNAIGELYVAGINLARGYVDQPGLSAERFVADPFV--PD 846
Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+++YRTGD L G + + GR D+QVKIRG R++L E++ A+ + VD V
Sbjct: 847 GSRMYRTGDVVRRLPDGTLEFRGRMDAQVKIRGFRIELAEIEEALRGLAGVDQAAVTVSK 906
Query: 381 VESSNPEILAFVTI--NPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++L FVT E + + ++ L DYM+P +++I +P+ NGK+
Sbjct: 907 NRAGYDQLLGFVTPAGGLEDELDVAELRRQVRRQLPDYMVPASIVQITAIPLTPNGKL 964
Score = 83.8 bits (198), Expect = 2e-15
Identities = 58/179 (32%), Positives = 92/179 (51%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
T IG I N Y+LD+ + V G PGE+ +AG ARGY + G+ RF+ NP
Sbjct: 1861 TPTIGRGIGNTDAYVLDQFLAPVPAGVPGELYLAGPGEARGYDQRPGETAARFVANPFVA 1920
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ +++YRTGD G + + R D QVK+RG R++L E++ AV++ P V V +
Sbjct: 1921 --DGSRMYRTGDLVRRAADGSLEFLSRTDDQVKVRGFRIELGEIEAAVASHPDVSRAVAV 1978
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
G + ++A+ T S + L DYM+P V + + +P+ +GK+
Sbjct: 1979 ADGDPAH--RVVAYYT----GAASPAELRGVAGEKLPDYMVPAVFMNVPAIPLTAHGKL 2031
Score = 83.0 bits (196), Expect = 4e-15
Identities = 61/181 (33%), Positives = 95/181 (52%), Gaps = 9/181 (4%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHNTHP 200
+G P + +Y+LD ++ V G GE+ VAG LARGY RG+ RF+ +P
Sbjct: 2983 LGQPTAATRLYVLDARLQHVTAGAAGELYVAGPQLARGY-RGRPDLTSERFVADPFAGRG 3041
Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD G +++AGR D Q+KIRG RV+ EV+ AV + V VV
Sbjct: 3042 E--RMYRTGDVVYRHADGRLVFAGRNDDQLKIRGFRVEPGEVERAVRSTKGVREAVVRA- 3098
Query: 378 GVESSNPEILAFVT-INPEARMSAK---NIEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542
V + ++A+V N A A+ + + + DYM+P V+ ++ +P+ +GK
Sbjct: 3099 AVNDAGTRLVAYVVPANSPAMADAELSDVVRTHVRGLVPDYMVPSAVVVLDKIPLTQHGK 3158
Query: 543 V 545
V
Sbjct: 3159 V 3159
>UniRef50_Q8YTR8 Cluster: Peptide synthetase; n=2; Nostocaceae|Rep:
Peptide synthetase - Anabaena sp. (strain PCC 7120)
Length = 2459
Score = 101 bits (243), Expect = 8e-21
Identities = 64/182 (35%), Positives = 102/182 (56%), Gaps = 7/182 (3%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T PIG I+N VY+LD++++ V G PGE+ +AG +ARGY + + RFI+
Sbjct: 796 TPPIGRAIANTQVYILDKHLQPVPVGVPGELYIAGAGVARGYWQRPELTAERFINQQSTV 855
Query: 195 HPNFAK---LYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362
+ + LY+TGD L G I Y GR D+QVKIRG+R++L E+D +S P +
Sbjct: 856 NSQQSTVNTLYKTGDRVRYLPDGNIEYLGRLDNQVKIRGYRIELGEIDALLSQYPEIQES 915
Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539
VV+ S + ++A++ P+ ++ ++ LT L YMIP + ++ +P NG
Sbjct: 916 VVIASETSSGDKNLVAYIA--PK-NINIADLRHYLTDKLPGYMIPAHFMTLDALPRNPNG 972
Query: 540 KV 545
K+
Sbjct: 973 KI 974
Score = 80.6 bits (190), Expect = 2e-14
Identities = 51/171 (29%), Positives = 86/171 (50%), Gaps = 11/171 (6%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIH----- 179
++P G ++N VY+L+ ++ GE+ ++G +A+GY + + +FI
Sbjct: 1877 SIPYGYSLTNQQVYVLNHSLEPCPTWAIGEIYISGLGVAKGYWQNPELTAEKFIQLDMGE 1936
Query: 180 --NPHNTHPNF-AKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP 347
P HP LY+TGD G L G I + GR D QVKI G+R++L E++ A+ P
Sbjct: 1937 NFPPTPLHPYTPTPLYKTGDLGRYLSDGTIEFLGREDFQVKINGYRIELGEIEAALQQHP 1996
Query: 348 CVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ 500
+ VV G S +++A++ + PE S + +SS D+ + Q
Sbjct: 1997 AITQAVVTTAGNALSQQQLVAYLVLQPEVIASQNTLN---SSSQLDFKLQQ 2044
>UniRef50_Q8CQA8 Cluster: Surfactin synthetase; n=14;
Staphylococcus|Rep: Surfactin synthetase - Staphylococcus
epidermidis (strain ATCC 12228)
Length = 2400
Score = 101 bits (243), Expect = 8e-21
Identities = 61/178 (34%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG+PIS VY++ N C G PGE+C+ G LA+GY+ RFI +P N
Sbjct: 742 IPIGLPISGTTVYVMQGNRIC-GVGVPGELCIGGAGLAKGYLNQPKLTAERFIQSPFNNE 800
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
LYR+GD L + G I Y R D QVKIRG R++L E++ A+ I ++ VV+
Sbjct: 801 ----MLYRSGDLVRLQEDGYIDYISRIDKQVKIRGFRIELSEIEKALEAIRDINKAVVI- 855
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + +I+A+ S ++ L+ +L +YM+P ++++ +P+ +NGK+
Sbjct: 856 VREQDQDKQIVAY--YEASQLKSTGQLKDILSETLPEYMVPVHFMKVDRIPITMNGKL 911
Score = 91.9 bits (218), Expect = 9e-18
Identities = 55/179 (30%), Positives = 97/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T+PIG P++N ++++ C G PGE+C+AG +L GY+ + +FI+NP
Sbjct: 1758 TIPIGKPLANVDIFIMSGGKLC-GVGIPGELCIAGESLTSGYLNRPELSAEKFINNPFGP 1816
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LYR+GD ++ G I + GR D QVK+ G+R++L E+++ ++++ V + VV+
Sbjct: 1817 ----GQLYRSGDLARLMPDGQIEFLGRIDKQVKVHGYRIELGEIENIINSVDTVTDSVVI 1872
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545
+ E+L + ++ +I L L YMIP+ + I +P+ N KV
Sbjct: 1873 L--AKQGEREVLHAYYVG--SQEDENHISQHLNQYLPKYMIPKTLTAISEIPLTGNDKV 1927
>UniRef50_Q63CQ6 Cluster: Multifunctional nonribosomal peptide
synthetase; n=1; Bacillus cereus E33L|Rep:
Multifunctional nonribosomal peptide synthetase -
Bacillus cereus (strain ZK / E33L)
Length = 3044
Score = 101 bits (243), Expect = 8e-21
Identities = 61/180 (33%), Positives = 103/180 (57%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
+ +PIG P+SN VY+L +N C +G GE+C++G +A+GY+ FI P
Sbjct: 760 VNIPIGKPVSNYKVYILHKNDLCA-QGILGEICISGRGVAKGYLNNSKLTEEVFIRCPAI 818
Query: 192 THPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
T +YRTGD G ++ G + GR D QVKIRG RV+LQE++ + + V VV
Sbjct: 819 TDE---VIYRTGDIGFINPDGEVELVGRMDEQVKIRGFRVELQEIESTLKGVEGVKEAVV 875
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++ N + L + + +++ I+ L++ L +YM+P+ +I ++ +P+L NGK+
Sbjct: 876 V--RQKNLNDDFLVAYFVG-DKKVNDLIIKDNLSNRLPEYMVPEFIIRLDEIPLLPNGKI 932
Score = 80.2 bits (189), Expect = 3e-14
Identities = 54/178 (30%), Positives = 93/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197
V +G PI N ++++EN + V G GE+ V G +A GY+ + +F+ +P+
Sbjct: 2262 VLVGKPILNTSAFIMNEN-KLVGIGMIGELFVGGHGVATGYLNNEKLSKEKFVDHPYEEG 2320
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
LY+TGD + G I GR QVKIRG R++L E++ + + + + VV+
Sbjct: 2321 E---VLYQTGDLARWNADGNIELFGRIGEQVKIRGFRIELGEIESYIRQVKDITDSVVV- 2376
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+I+A+ T E +S ++ L+ L DYM+P+ I++ +P +NGK+
Sbjct: 2377 LDTNDRTEKIVAYFTARKEIDIS--RLKELLSKKLNDYMVPEHFIQLAGIPKTINGKI 2432
>UniRef50_Q63CQ5 Cluster: Multifunctional nonribosomal peptide
synthetase; n=1; Bacillus cereus E33L|Rep:
Multifunctional nonribosomal peptide synthetase -
Bacillus cereus (strain ZK / E33L)
Length = 2295
Score = 101 bits (243), Expect = 8e-21
Identities = 53/178 (29%), Positives = 107/178 (60%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197
VPIG P+SN +Y++++ G GE+C+ G +++ GY+ +FI NP H
Sbjct: 2016 VPIGKPVSNTKLYVINQFGNLCGIGMTGELCITGESVSLGYLNQPILTDEKFIPNPFKKH 2075
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
K+Y+TGD +G + + GR D+Q+K+RG R+++QE++ A+ + + VV+
Sbjct: 2076 ---TKMYKTGDLVRWTTQGTLEFLGRKDNQIKLRGFRIEIQEINAALKAYKGIQDAVVIM 2132
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
G ++ ++ A++ I+ E ++ ++ E++ +L +YM+P+ ++++E +P +NGK+
Sbjct: 2133 RG-QNEEKDLCAYI-ISKE-KIDIDSLRKEISETLPEYMLPRYIVQLEKMPRTLNGKI 2187
Score = 85.8 bits (203), Expect = 6e-16
Identities = 55/178 (30%), Positives = 91/178 (51%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197
V +G PI N +Y++ +N C E GE+CV G + RGY+ +++ P ++
Sbjct: 514 VSVGKPIGNGEIYIVKDNKLCGISME-GELCVGGEGVTRGYLNQPVLTDEKYVVIPEISN 572
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++Y+TGD G + G + GR D QVKI G+R++L E++ + I +++ VV+
Sbjct: 573 ---GRIYKTGDVGYWREDGTLKLLGRRDEQVKINGYRIELSEIESGLRQIEGINDAVVI- 628
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
Y P +AF S I+ L +L YMIP ++++E P V GK+
Sbjct: 629 YDQSEKIPLFVAF--YRGTKFESTNKIKELLRKNLPSYMIPNDIVKVEDFPQTVGGKL 684
>UniRef50_Q9Z5F4 Cluster: Ta1; n=4; Bacteria|Rep: Ta1 - Myxococcus
xanthus
Length = 2393
Score = 101 bits (243), Expect = 8e-21
Identities = 64/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V IG PI N VY+LD+ M+ V G PGE+ +AG +A GY+ RF+ NP
Sbjct: 733 VTIGKPIDNTQVYVLDDRMQPVPIGVPGELWIAGAGVACGYLNRPALTAERFVSNPFT-- 790
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P LYRTGD G + Y GR D QVK+RG R+++ E++ ++ P V NC V+
Sbjct: 791 PG-TTLYRTGDLARWRADGEVEYLGRLDHQVKVRGFRIEMGEIEAQLAGHPSVKNCAVVA 849
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++ +++A+ + I A L L DYM+P V ++ +P+ NGKV
Sbjct: 850 KELNGTS-QLVAYCQ-PAGTSFDEEAIRAHLRKFLPDYMVPAHVFAVDAIPLSGNGKV 905
>UniRef50_Q2ANX0 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Bacillus weihenstephanensis KBAB4|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Bacillus weihenstephanensis KBAB4
Length = 1476
Score = 101 bits (243), Expect = 8e-21
Identities = 61/180 (33%), Positives = 99/180 (55%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
++VPIGVP N +Y+LD ++R V G GE+ ++G +ARGY +D RFI NP++
Sbjct: 746 VSVPIGVPAQNMKIYVLDSDLRPVPMGVVGEIYISGEGVARGYFNNQDLTRERFIVNPYS 805
Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
++Y++GD ++ I Y GR D QVK+RG R++L+E++ + P + VV
Sbjct: 806 EK---EQMYKSGDLARFIEGDKIEYLGRKDDQVKVRGFRIELKEIEINLQKYPSIKEVVV 862
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ N + A+ T N A++ + L L YMIP I ++ +P+ NGK+
Sbjct: 863 IDQEDYDGNHYLCAYYTEN--AKVKTSELFRFLKEILPVYMIPSYFIVLKEIPLTFNGKL 920
>UniRef50_Q1D8L0 Cluster: Non-ribosomal peptide synthetase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthetase - Myxococcus xanthus (strain DK 1622)
Length = 1555
Score = 101 bits (243), Expect = 8e-21
Identities = 60/178 (33%), Positives = 93/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197
VPIG PI+N Y+LD R + G GE+ + G + RGY D RF+ +P ++
Sbjct: 1256 VPIGTPIANTQFYILDAQQRPLPIGAAGELYIGGEGVVRGYHHRPELDRERFVPDPFSSQ 1315
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YRTGD G++ Y GR D QVK+RG R++L E++ + P V VV+
Sbjct: 1316 PG-AQMYRTGDAARWRHDGLVEYIGRLDHQVKVRGFRIELGEIESRLGEHPAVRETVVIV 1374
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A++ P +A + L + L +YM+PQ + + T P N KV
Sbjct: 1375 REDIPGDKRLVAYLIAKPGEPPAADALREFLRTRLPEYMVPQSFVTLSTFPQTPNKKV 1432
>UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 5741
Score = 101 bits (243), Expect = 8e-21
Identities = 57/178 (32%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD +R + G PGE+ + G +ARGY + RF+ +P +++
Sbjct: 1838 VPIGTPIANTSLYVLDAELRPLPVGVPGELYIGGMGVARGYHARPELTAERFLPDPASSN 1897
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A++YRTGD G + + GR D Q+K+RG RV+ E++ ++ V VV+
Sbjct: 1898 AG-ARMYRTGDRARWRADGTVEFLGRVDHQLKVRGFRVEPGEIESVLARHSDVAQAVVVA 1956
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V P +S + + A SL ++M+P + ++ +P+ NGKV
Sbjct: 1957 REASAGGARLVAYVVARPGTALSVEALLAFSRRSLPEHMVPSAFVPLDALPLTPNGKV 2014
Score = 99.1 bits (236), Expect = 6e-20
Identities = 63/178 (35%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N +Y+LD +R V G PGE+ + G LARGY + D RF+ +
Sbjct: 2899 VPIGRPIANARMYVLDARLRPVPAGVPGELYIGGAPLARGYWQRPDLTAERFLPDAFAAQ 2958
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YRTGD L G I Y GR D QVK+RG R++L E++ +S P V V
Sbjct: 2959 PG-ARMYRTGDQARFLANGAIEYLGRLDDQVKLRGFRIELGEIEAVLSLHPGVRAAAVAI 3017
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V + P + A + A L L ++M+P + ++ +P+ +GK+
Sbjct: 3018 REDVPGDRRLVAYV-VAPSGDV-ASELRAFLGERLPEHMVPSAFVTLDALPLSPSGKL 3073
Score = 96.7 bits (230), Expect = 3e-19
Identities = 64/183 (34%), Positives = 100/183 (54%), Gaps = 7/183 (3%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHN 191
+++PIG P++N Y+LDE+M V G GE+ + G LA GY+ RF+ NP +
Sbjct: 4375 VSIPIGRPLANTVQYVLDEDMAPVPPGGVGELWLGGDGLAWGYLGQPALTAERFVPNPFS 4434
Query: 192 THPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
P +L+RTGD +L G + + GR D+QVK+RG RV+ EV+ A+ P V VV
Sbjct: 4435 ERPG-TRLFRTGDRVRLLADGAVTFEGRVDAQVKVRGFRVEPGEVEAALLRHPDVRQAVV 4493
Query: 369 LCYGVES-SNPEILAFVTINPEARMSAKN--IEAELTSSLTDYMIPQV-IEIETVPVLVN 536
L E+ + ++A+V EA + + + L + L YM+P + + +P+ N
Sbjct: 4494 LAREDEAGGSRRLVAYVVPTAEAAATPEPSLLRTFLAAHLPAYMVPAAFMVLGRLPLTPN 4553
Query: 537 GKV 545
GKV
Sbjct: 4554 GKV 4556
Score = 94.7 bits (225), Expect = 1e-18
Identities = 56/178 (31%), Positives = 92/178 (51%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+PIG PI+N VY++D +R V G PGE+ + G LA GY + RF+ NP +
Sbjct: 5434 IPIGRPIANTRVYVVDAALRPVPVGVPGELLIGGDGLAWGYQGRPELTAERFVPNPFGSE 5493
Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD + G + + R D QVK+RG+RV+ EV+ A+ P V VV+
Sbjct: 5494 AG-GRLYRTGDSVRYREDGTLEFLERLDGQVKVRGYRVEPGEVEEALRLHPSVAEAVVVA 5552
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+ + + + L SL ++M+P ++ + +P+ GK+
Sbjct: 5553 RPDPAGGKRLVAYAVPRAGETLDPRGLRGFLAESLPEFMVPSTLVPLMALPLTPVGKL 5610
Score = 34.7 bits (76), Expect = 1.4
Identities = 21/86 (24%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
Frame = +3
Query: 72 ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFA-KLYRTGDFGILDK 248
E R GE+ V+G ++A GY + + + RTGD G+L
Sbjct: 411 ETRRACPPERVGEIWVSGPSVAHGYWERPEESEAAFGARLADSDSGPRFLRTGDLGLLKD 470
Query: 249 GVILYAGRADSQVKIRGHRVDLQEVD 326
G + GR + +RG + Q+++
Sbjct: 471 GELFVVGRRKDLIILRGRNLHPQDLE 496
>UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8;
Bacteria|Rep: Non-ribosomal peptide synthase - Myxococcus
xanthus (strain DK 1622)
Length = 3906
Score = 101 bits (243), Expect = 8e-21
Identities = 63/185 (34%), Positives = 101/185 (54%), Gaps = 10/185 (5%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVPIG P+SN VY++D + V G GE+ + G ++RGY+ + RFI NP ++
Sbjct: 3595 TVPIGRPVSNTEVYIVDAHGTPVPMGAAGELLIGGEGVSRGYLHRPELTAERFIPNPFSS 3654
Query: 195 HPNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A+LYRTGD G +L + GR D QVKIRG+R++L EV+ + P + V+
Sbjct: 3655 RPG-ARLYRTGDACRYQPGGVLEFLGRIDQQVKIRGYRIELGEVEAVLREHPALREAAVV 3713
Query: 372 CYGVESSNPEILAFVTIN----PEARMSA--KNIEAELTSSLTDYMIPQV-IEIETVPVL 530
+ ++A++ + P + A ++ A L L +YM+P + +E +P+
Sbjct: 3714 ARTQDDDAARLVAYLVPSQRDTPLENLQALVAHVRAFLRERLPEYMVPSAFVPLEALPLN 3773
Query: 531 VNGKV 545
+GKV
Sbjct: 3774 ASGKV 3778
Score = 101 bits (242), Expect = 1e-20
Identities = 60/179 (33%), Positives = 96/179 (53%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG PISN +++L+ + V G PGE+C G LA GY+ RFI +P +
Sbjct: 2532 VPIGRPISNTRIHVLNAALEPVPVGAPGELCAGGDGLALGYLNDPALTAQRFIPDPFSPV 2591
Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+LYRTGD +L G + + GR D QVK+RG R++ E++ A++ P V V+
Sbjct: 2592 PG-ARLYRTGDRCHVLPDGRVEFLGRVDEQVKLRGFRIEPGEIEAALALHPTVHEARVMA 2650
Query: 375 YGVESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+++A++ P + A+++ L + L +M+P + + P+ NGKV
Sbjct: 2651 REDGPGEKQLVAYLVARPSRELPPAEDLRRYLQARLPVFMVPSAFVTLAAFPLTANGKV 2709
Score = 97.5 bits (232), Expect = 2e-19
Identities = 59/178 (33%), Positives = 93/178 (52%), Gaps = 4/178 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVPIG P++N +Y+LD + + G PGE+ + G + RGY+ D RF+ +
Sbjct: 1472 TVPIGQPVANTALYVLDTRLAPLPVGVPGELYIGGVQVGRGYLGRPDLTAERFVPDGFAR 1531
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
++YRTGD +L G + Y GR D QVK+RGHR++L E++ + P V VVL
Sbjct: 1532 EEGM-RMYRTGDRARVLPDGSLEYLGRLDHQVKVRGHRIELGEIEATLEQHPAVQQAVVL 1590
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGK 542
+ +++AF++ A A + L L +M+P I I +P+ +GK
Sbjct: 1591 ARTAVGDDVQLVAFISHRGHAPTPA-TLRDFLAERLPGFMVPSHIGILAELPLGPSGK 1647
Score = 40.3 bits (90), Expect = 0.028
Identities = 32/158 (20%), Positives = 66/158 (41%), Gaps = 3/158 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVR-EGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
V G + + ++D R ++ +GE GE+ ++G ++A+GY + +
Sbjct: 381 VSSGTQLPTQSLVVVDPQARTLQADGEVGEIWMSGPSVAQGYWGRPEETERVFQARLARG 440
Query: 201 NFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV-STIPCVDNCVVLCY 377
RTGD G L G + GRA + IRG Q+++ + P + +
Sbjct: 441 E-GPFLRTGDLGFLRDGQLFVTGRAKDLIIIRGRNHYPQDLEQTTEQSHPAIRPGCSAAF 499
Query: 378 GVESSNPEILAFV-TINPEARMSAKNIEAELTSSLTDY 488
V+ E LA ++ +S ++ + ++ ++
Sbjct: 500 SVDVDGEEHLAVAFEVSARQEVSPDDVATSVQQAIAEH 537
>UniRef50_Q0VZ70 Cluster: Non ribosomal peptide synthase; n=1;
Chondromyces crocatus|Rep: Non ribosomal peptide synthase
- Chondromyces crocatus
Length = 3912
Score = 101 bits (243), Expect = 8e-21
Identities = 57/177 (32%), Positives = 96/177 (54%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200
PIG P+ + +Y+LD ++R V G PG++ + G L RGY+ R+I +P + P
Sbjct: 2794 PIGCPLQSTEIYILDAHLRPVPVGVPGDLYIGGAKLTRGYIHRPALTAERYIPHPFSDRP 2853
Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LY TGD G I + GR D+QVK+RG+R++L EV+ A++ P V VV+
Sbjct: 2854 G-ARLYVTGDIARYQLDGTIDFLGRRDNQVKVRGYRIELGEVEAALNDHPGVREAVVVAQ 2912
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A+ + + + L+ L YMIP V + ++ +P+ GK+
Sbjct: 2913 KDGAGDNRLVAYWAAKSTPPTTTEALRDALSKRLAAYMIPSVFVRMDALPLNATGKI 2969
Score = 91.5 bits (217), Expect = 1e-17
Identities = 48/121 (39%), Positives = 73/121 (60%), Gaps = 3/121 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+PIG P N VYLLD ++ V G PGE+ VA LARGY+ +F+ NP +
Sbjct: 795 LPIGRPFYNKRVYLLDARLQPVPVGVPGEIYVASPGLARGYINRPAATAEKFLPNPFSET 854
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD L G +++ GR D+QVK+RG R++L+E++ A+ + P V + V+
Sbjct: 855 PG-ERIYRTGDLARYLPDGNLVFLGRVDNQVKLRGLRIELEEIESALKSHPHVGDAAVIV 913
Query: 375 Y 377
+
Sbjct: 914 H 914
>UniRef50_A7BKL9 Cluster: Non-ribosomal peptide synthetase; n=2;
Beggiatoa sp. SS|Rep: Non-ribosomal peptide synthetase -
Beggiatoa sp. SS
Length = 627
Score = 101 bits (243), Expect = 8e-21
Identities = 61/179 (34%), Positives = 98/179 (54%), Gaps = 6/179 (3%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG P++N VY+LD + PGEVC+AG +ARGY+ + +FI
Sbjct: 330 PIGKPVANYQVYVLDTENALLPINIPGEVCIAGAGVARGYLNRPELTAEKFIEVV--LFG 387
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++Y+TGD L G + Y GR D QVK+RG R++L E++ + P V VV+ Y
Sbjct: 388 KRERIYKTGDLARWLPDGNLEYLGRIDHQVKLRGFRIELGEIEAVLCQHPEVKEAVVVLY 447
Query: 378 GVESSNPEILAFVTINPEARMS--AKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ N ++A+V+++ E + A ++ L L DYMIP ++ ++ +P+ NGK+
Sbjct: 448 DAD-DNKRLVAYVSVDKELTQADLASELKNSLKQQLPDYMIPADLMVLDALPLTSNGKI 505
>UniRef50_A5W120 Cluster: Amino acid adenylation domain; n=3;
Bacteria|Rep: Amino acid adenylation domain - Pseudomonas
putida F1
Length = 5230
Score = 101 bits (243), Expect = 8e-21
Identities = 63/180 (35%), Positives = 102/180 (56%), Gaps = 6/180 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VP+G P++N Y+LD +++ + G GE+ +AG +ARGY R RF+ NP
Sbjct: 824 VPLGRPLANMQAYVLDASLQPLSTGCQGELYLAGAGVARGYHRRAAMTAERFVPNPFGAA 883
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ ++YRTGD L G + Y GR D QVKIRG+R++L E+ + P V + V +
Sbjct: 884 GS--RVYRTGDLARQLANGQVDYLGRVDHQVKIRGYRIELGEITDTLKRQPRVHDAVAVI 941
Query: 375 YGVESSNPEILAFVTINPEARMS--AKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+G S+ I+A+V + +A S + +A L L DYM+P + + + +P+ +NGK+
Sbjct: 942 HGTGSA-ARIVAYVVPDSQADASQVLADAQAALARQLPDYMLPSRFMALPGMPLTLNGKL 1000
Score = 99.5 bits (237), Expect = 4e-20
Identities = 65/180 (36%), Positives = 95/180 (52%), Gaps = 6/180 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHN--PHNTH 197
+PIG P NN +Y+LD + G GE+CVAG + RGYV DP R PH
Sbjct: 3407 LPIGSPTDNNRLYVLDAALELAPLGVTGELCVAGTGVGRGYV--GDPLRTAQAFIPHPCG 3464
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD GV+ Y GR D QVKIRG R++L E++ A+ V VV+
Sbjct: 3465 APGERLYRTGDLARRRADGVLEYVGRVDHQVKIRGFRIELGEIEAALLDSDQVREAVVMA 3524
Query: 375 YGVESSNPEILAFVTINPEARMSA--KNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ P+++A+ + A + ++A L + L DYM+P + + +P+ NGKV
Sbjct: 3525 Q-PGANGPQLVAYCVADDAVAADALKQQLKASLKARLPDYMVPVHWVLMARLPLTPNGKV 3583
Score = 91.9 bits (218), Expect = 9e-18
Identities = 64/183 (34%), Positives = 102/183 (55%), Gaps = 10/183 (5%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
P+GVPI + Y+LD ++ V +G GE+ V LARGY++ D RF+ +P P
Sbjct: 4937 PMGVPIPDLSWYVLDGDLNPVAKGCIGELYVGRAGLARGYLKRSDLSATRFVPDPFGA-P 4995
Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+LYRTGD GVI YAGR D QVKIRG R++L E++ + P V +VL
Sbjct: 4996 G-GRLYRTGDLARYHADGVIEYAGRIDHQVKIRGFRIELGEIEARLQAQPQVREALVLAQ 5054
Query: 378 GVESSNPEILAF------VTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVN 536
++ +++A+ V + +A + A+ + +L +L DYM+P ++ ++ P+ N
Sbjct: 5055 -EGATGQQLVAYLIPAAEVALEQQAGLRAQ-LREQLKEALPDYMVPAHLLLLDRWPLTAN 5112
Query: 537 GKV 545
GK+
Sbjct: 5113 GKL 5115
Score = 85.0 bits (201), Expect = 1e-15
Identities = 60/182 (32%), Positives = 92/182 (50%), Gaps = 9/182 (4%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200
PIG P+ +LD + + G G++ + G LARGY+ G RF+ +P T
Sbjct: 1882 PIGQPVGERSACVLDAALGLLPAGVAGQLYLGGAGLARGYLGRPGLTAERFVPDPFGTEG 1941
Query: 201 NFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LYRTGD + G Y GR D+QVKIRG RV+L E++ + V VV+
Sbjct: 1942 --ARLYRTGDQVRLRADGQFDYLGRIDNQVKIRGFRVELGEIEACLLACAEVREAVVVAV 1999
Query: 378 GVESSNPEILAFVTINPEARM-----SAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539
S ++ A++ + + ++A L SL DYM+P + +E +P+L NG
Sbjct: 2000 D-GPSGKQLAAYLVLADSIAAHGPAEQREQLKAALRQSLPDYMLPTHWLVLEQLPLLPNG 2058
Query: 540 KV 545
K+
Sbjct: 2059 KL 2060
>UniRef50_A5EHY7 Cluster: Non ribosomal peptide synthase; n=1;
Bradyrhizobium sp. BTAi1|Rep: Non ribosomal peptide
synthase - Bradyrhizobium sp. (strain BTAi1 / ATCC
BAA-1182)
Length = 1134
Score = 101 bits (243), Expect = 8e-21
Identities = 62/178 (34%), Positives = 92/178 (51%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-NTH 197
P+G P+ N +++LD + + G PGE+C+AG +ARGYV + RF+ NP +
Sbjct: 853 PLGWPVDNTELHILDGRLLPMPLGVPGELCIAGIGVARGYVSRPELTRERFVGNPFADGV 912
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+ A+LYRTGD L G I + GR D QVKIRG RV+L E++ + V VV
Sbjct: 913 PHMARLYRTGDVARRLPDGAIEFLGRRDFQVKIRGFRVELGEIEAVLLEQSDVAQAVVAR 972
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ E+ + R L L DYM+P +I ++ +P+ NGK+
Sbjct: 973 RATDGR--ELTVAYLVGRNGRPDLARTHERLRQRLPDYMVPDHIIVLDALPLSANGKL 1028
>UniRef50_A3YGI9 Cluster: Amino acid adenylation; n=1; Marinomonas sp.
MED121|Rep: Amino acid adenylation - Marinomonas sp.
MED121
Length = 1372
Score = 101 bits (243), Expect = 8e-21
Identities = 62/176 (35%), Positives = 100/176 (56%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
+G + + VYLLD+ M V G+ GE+ +AG NL+RGY+ D R++ NP
Sbjct: 816 LGNVMGDTQVYLLDQYMNPVISGQVGELYIAGSNLSRGYLNATDLTAGRYLPNPFVAGGR 875
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
F Y++GD + +G I GRAD QVKIRG R++L+E++ +++ V + VL G
Sbjct: 876 F---YQSGDLAMRRAEGCIDILGRADQQVKIRGFRLELEEIESLLASHQTVQHSSVLLQG 932
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
E ++AF + + ++A L ++L DYM+P Q+I ++ +P+ NGKV
Sbjct: 933 -EGDQAHLVAFAVPYVGGALDEETLKAWLAANLPDYMVPTQLISVKYLPLNANGKV 987
>UniRef50_Q88JT4 Cluster: Antibiotic biosynthesis protein, putative;
n=4; Pseudomonas|Rep: Antibiotic biosynthesis protein,
putative - Pseudomonas putida (strain KT2440)
Length = 923
Score = 101 bits (242), Expect = 1e-20
Identities = 63/178 (35%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VP+G I++ + +++ + V EGE GE+ + L+RGY G +FI NP T
Sbjct: 334 VPLGKGIADAQLLVINPANQLVSEGETGEILIRSPYLSRGYWDDPGLTEAKFIANPF-TA 392
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ YRTGD G L G + GRADSQVKIRGHR++L E+++A+ P + CVVL
Sbjct: 393 DTADRCYRTGDLGTYLADGSARFLGRADSQVKIRGHRIELAEIENAICRHPHIGQCVVLT 452
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
E ++ ++A+ R A + L+ L DYM+P + + ++ +P+ N KV
Sbjct: 453 -NHEGASTRLVAYCVAQQAIR--ADELRQALSGQLPDYMVPALFVFLDALPLTPNAKV 507
>UniRef50_Q6VT95 Cluster: Mixed type I polyketide
synthase/nonribosomal peptide synthetase; n=3;
Bacteria|Rep: Mixed type I polyketide
synthase/nonribosomal peptide synthetase - symbiont
bacterium of Paederus fuscipes
Length = 8601
Score = 101 bits (242), Expect = 1e-20
Identities = 61/179 (34%), Positives = 99/179 (55%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+V IG PI+N VY+L+ + + V G PGE+C+AG LARGY+ +FI NP
Sbjct: 1529 SVDIGTPIANTRVYILNGDDQLVPIGVPGELCIAGDGLARGYLGNPQLTAQKFIANPF-- 1586
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +LYRTGD + GV+ + GR D QVK+RG+R++L +++ ++ P V +V+
Sbjct: 1587 EPG-NRLYRTGDLARWREDGVLEHLGRLDQQVKVRGYRIELSDIETWLNRHPSVAQSLVV 1645
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
+ + +V + A +S+ + L L +YM+P + +P++ NGKV
Sbjct: 1646 GHEQAGGMLLVAYYVKDSEWASVSSTELRNYLAEHLPEYMVPAFFRALSNMPLMPNGKV 1704
>UniRef50_Q1D3T0 Cluster: Non-ribosomal peptide synthase MxaA; n=2;
Cystobacterineae|Rep: Non-ribosomal peptide synthase MxaA
- Myxococcus xanthus (strain DK 1622)
Length = 1515
Score = 101 bits (242), Expect = 1e-20
Identities = 63/179 (35%), Positives = 94/179 (52%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
T IG P+ N VY+LD N + G PGEV + G +ARGY+ + RF+ +P
Sbjct: 839 TPTIGRPVGNTQVYVLDANREPMPVGVPGEVYIGGHGVARGYLGRTELTAERFVTSPFAG 898
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A LYRTGD L G + Y GR D QVK+RG R++L E+ A+ P + + VV+
Sbjct: 899 DAG-AHLYRTGDLARWLPDGQLEYLGRMDHQVKLRGFRIELGEIGAALQEHPGIRDAVVV 957
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ +++A+V + L S L +YM+P V + +E +P+ NGKV
Sbjct: 958 VREGPGADKQLVAYVVGRDGKAPEPGALRDHLKSRLPEYMVPFVFVGLEALPLTPNGKV 1016
>UniRef50_Q0SKF9 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 8928
Score = 101 bits (242), Expect = 1e-20
Identities = 65/179 (36%), Positives = 94/179 (52%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG P+ N VY+LD + V G GE+ +AG LARGYV D RF+ NP
Sbjct: 2108 SVPIGAPVWNTQVYVLDSRLHPVPVGVHGELYLAGIQLARGYVGRSDLTSDRFVANPFGA 2167
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD G I Y GR D QVK+RG R++L EV+ AV P V VV
Sbjct: 2168 -PG-QRMYRTGDVVRWRADGNIEYIGRRDFQVKLRGQRIELGEVEAAVLAHPSVAQAVVT 2225
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ E++ ++ +V A + + +L YM+P ++I ++ P+ GK+
Sbjct: 2226 VHRSEATGESLVGYVIPVAGADIDTAVVRDAAAEALPAYMVPTRIIVLDRFPLGATGKL 2284
Score = 87.0 bits (206), Expect = 2e-16
Identities = 55/178 (30%), Positives = 91/178 (51%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
+ +G PI +LD ++ V G PGE+ + G LARGY R + RF+ NP
Sbjct: 7337 ITLGGPIRGVGELVLDSRLQPVPVGVPGELYITGAGLARGYHRRPELSSQRFVANPFGEA 7396
Query: 198 PNFAKLYRTGDFGILDKG-VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD + Y GR+D QVKIRG R++L E+D+ ++T P V L
Sbjct: 7397 GE--RMYRTGDIVRWRADHTVEYVGRSDFQVKIRGFRIELGEIDNEIATFPGVSFAATLG 7454
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
S + ++ ++ N + + A L++ L +M+P V+ ++ +P+ GK+
Sbjct: 7455 VPGPSGDTVLVTYLLPNTAGGVDPAELTAHLSTRLPAHMVPTSVMFLDEIPLTPVGKL 7512
Score = 84.2 bits (199), Expect = 2e-15
Identities = 55/179 (30%), Positives = 91/179 (50%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
TV IG P+ +LD ++ V G GE+ ++G LARGY G RF+ NP+
Sbjct: 4712 TVTIGAPVRGVSEVILDSRLQPVSVGVAGELYISGEGLARGYHARAGLTSERFVANPYGE 4771
Query: 195 HPNFAKLYRTGDFGILDKG-VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ ++YRTGD + Y GR D QVKIRG R++L ++D A++ P V V L
Sbjct: 4772 PGD--RMYRTGDLARWRSDHTVEYLGRTDFQVKIRGFRIELGDIDSALAAHPSVAFAVTL 4829
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ + ++++V E+ + ++ + L +M+P I I + +P+ GK+
Sbjct: 4830 GRPGPAGDTVLVSYVLPEAESALEPPELKEWTANLLPAHMVPSSIMILDEIPLTPVGKL 4888
Score = 84.2 bits (199), Expect = 2e-15
Identities = 55/176 (31%), Positives = 92/176 (52%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHPN 203
IG I+ +V++LD + V G GE+ V+G + RGY+ G RF+ +P P
Sbjct: 5802 IGRGIAGLHVHVLDRRLHPVPPGTIGEMYVSGDQVTRGYLGRAGLSSSRFVADP--LRPG 5859
Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YRTGD + G + Y GR+D QVKIRG R++L E++ A+ + VVL
Sbjct: 5860 -ARMYRTGDLARWNTDGQLEYLGRSDFQVKIRGFRIELGEIESALLRYRGIAQAVVLTRD 5918
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ +V A + + + + LT YM+P ++ ++ +P+ NGK+
Sbjct: 5919 DGHGGHRLIGYVVPESGATVEVSSALEFVGTQLTSYMVPATLVVLDALPLTSNGKL 5974
Score = 83.8 bits (198), Expect = 2e-15
Identities = 56/178 (31%), Positives = 90/178 (50%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
V IG P +LD + V G GE+ V+G LARGY G RF+ NP+
Sbjct: 3168 VTIGRPPMGTGEMVLDSRLHPVPNGVTGELYVSGSGLARGYKDRAGTTAERFVANPYGGL 3227
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A++YRTGD + G + Y GR+D QVKIRG R++L E++ A++ P V VV
Sbjct: 3228 G--ARMYRTGDLARWNGAGQLEYLGRSDFQVKIRGFRIELGEIETALTRYPGVARSVVSA 3285
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + ++ ++ A + + + + L YM+P +I ++ +P+ GK+
Sbjct: 3286 HRGSTGANRLVGYLVPTAGAELDPEAVLEFVGGFLAPYMVPSALIVLDELPLTPAGKL 3343
Score = 81.8 bits (193), Expect = 9e-15
Identities = 56/178 (31%), Positives = 88/178 (49%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNTH 197
V IG P + +LD + V G PGE+ + G +ARGY P RF+ +PH
Sbjct: 1041 VTIGRPSRGCGLLVLDSRLHPVPRGVPGELYITGDGVARGYHNRSIPTAERFVADPHGA- 1099
Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD + G + Y GR D QVKIRG R++L E+D V + P V +
Sbjct: 1100 PG-ERMYRTGDLARWNAAGQLEYLGRTDFQVKIRGFRIELGEIDAVVRSHPSVAFATTVG 1158
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
S + ++ +V + +I ++L +M+P +V+ + VP+ GK+
Sbjct: 1159 RTAPSGDTVLVTYVLPEDGTDIVVGDILEHAAAALPAHMVPARVMVLREVPLTPAGKL 1216
Score = 72.5 bits (170), Expect = 6e-12
Identities = 53/179 (29%), Positives = 85/179 (47%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197
V IG P +LDE ++ V G PGE+ + G LARGY RF+ P
Sbjct: 8394 VNIGAPALGFGSLVLDERLQPVPVGVPGELYITGPGLARGYHNRSALTSERFVACPFG-E 8452
Query: 198 PNFAKLYRTGDFGILDKG--VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD + +G I Y GR D QVK+RG R++L E+D ++ P V +
Sbjct: 8453 PG-RRMYRTGDV-VRWRGDHTIEYIGRTDFQVKVRGFRIELGEIDAVLARHPAVAFAATI 8510
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ S + + ++V + + L +M+P V+ ++ +P+ GK+
Sbjct: 8511 GHTGPSGDTLLASYVRAAEGHDLEPAELRTHAADRLPAHMVPSAVVVLDQIPMTPVGKL 8569
>UniRef50_A6P624 Cluster: Nonribosomal peptide synthetase; n=1;
Microcystis aeruginosa|Rep: Nonribosomal peptide
synthetase - Microcystis aeruginosa
Length = 1415
Score = 101 bits (242), Expect = 1e-20
Identities = 66/186 (35%), Positives = 100/186 (53%), Gaps = 14/186 (7%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP------ 185
IGVPI+N VYLLD ++ V G GE+ + G +A+GY+ + +FI NP
Sbjct: 846 IGVPIANTQVYLLDSYLQPVPIGIIGELYIGGIGVAQGYLNRPELTDEKFIPNPFIQDYD 905
Query: 186 HNTHPNFA----KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPC 350
P A K+Y+TGD L G I + GR D QVKIRG R++L E++ + P
Sbjct: 906 REKFPRNAFYQTKIYKTGDLARYLPDGKIEFLGRIDDQVKIRGIRIELGEIEARICQYPL 965
Query: 351 VDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPV 527
V +CVV Y ++ ++A++ ++ K ++A L + L MIP Q+I ++ P+
Sbjct: 966 VKDCVVAAYQADTGQ-HLVAYLVAQDALSINQKQLKAYLQNYLPISMIPSQIIILDAFPL 1024
Query: 528 LVNGKV 545
NGKV
Sbjct: 1025 TSNGKV 1030
>UniRef50_A4FEM4 Cluster: Non-ribosomal peptide synthetase modules;
n=1; Saccharopolyspora erythraea NRRL 2338|Rep:
Non-ribosomal peptide synthetase modules -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 1315
Score = 101 bits (242), Expect = 1e-20
Identities = 61/179 (34%), Positives = 98/179 (54%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V IG + V LLDE + V +G+ GE+C+ G +A GYV K RF+ +P
Sbjct: 325 VTIGRALPTYTVVLLDEALHPVPDGDVGEICIGGPGVANGYVGLPEKTADRFVEHP--LA 382
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +LYRTGD G + G I Y GRAD++VKIRG RVDL E+D+ + P V V
Sbjct: 383 PRGGRLYRTGDLGRTTEDGEIEYLGRADAEVKIRGRRVDLGEIDNVLLEHPAVSGAVT-- 440
Query: 375 YGVESSNPEILAFVTINPEARMS-AKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ + + +++T+ +A ++ + L +YM+P ++++ + +P + +GKV
Sbjct: 441 -ALTADGMALASYLTVRGDAGDELIADLHDRARAKLPEYMVPALVDVLDELPTMPSGKV 498
>UniRef50_A0UXD5 Cluster: Amino acid adenylation domain; n=1;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 2508
Score = 101 bits (242), Expect = 1e-20
Identities = 65/178 (36%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197
V IG PI+N Y+LD N + G PGE+CV+G LA+GY +FI NP
Sbjct: 2035 VLIGKPINNTKCYILDRNDKLQPIGVPGELCVSGHGLAKGYFNADKLTAEKFIDNPF--I 2092
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +YRTGD L G I + GR D QVKIRG+R+++ E++H + V VV
Sbjct: 2093 PG-ETMYRTGDMARWLPDGNIEFIGRIDQQVKIRGYRIEIGEIEHHLQMHTNVIEAVVTV 2151
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++ + A+ +N A + K +E L+ L +YM+PQ I++++ P NGK+
Sbjct: 2152 NDLDGQK-TLCAYTVLN--ANIKNKELEEYLSVRLPNYMVPQHFIKLDSFPKTPNGKI 2206
>UniRef50_UPI00015978D8 Cluster: NrsC; n=1; Bacillus amyloliquefaciens
FZB42|Rep: NrsC - Bacillus amyloliquefaciens FZB42
Length = 3411
Score = 101 bits (241), Expect = 1e-20
Identities = 60/178 (33%), Positives = 101/178 (56%), Gaps = 3/178 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTH 197
++P G P+SN Y+L+ EN C G GE+ + G +A GY+ K+ H
Sbjct: 862 SIPYGYPLSNQTYYVLNYENDPCPI-GVKGELFIGGKGVAEGYLNDKEK---TEASFIDH 917
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+F ++YRTGD G+L +G I + GR D Q+K+RG+RV+L E++ + V N VV+
Sbjct: 918 PDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVRGYRVELGEIESVILEHRQVRNAVVI- 976
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++ N ++L + + + +++ L+ + +YMIP +++IE VP+ NGKV
Sbjct: 977 NQKDARNQDVL-YAYVAGHQSLPPTDLKEFLSLKVPEYMIPSYIVQIEEVPLTSNGKV 1033
Score = 101 bits (241), Expect = 1e-20
Identities = 60/178 (33%), Positives = 101/178 (56%), Gaps = 3/178 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTH 197
++P G P+SN Y+L+ EN C G GE+ + G +A GY+ K+ H
Sbjct: 1910 SIPYGYPLSNQTYYVLNYENDPCPI-GVKGELFIGGKGVAEGYLNDKEK---TEASFIDH 1965
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+F ++YRTGD G+L +G I + GR D Q+K+RG+RV+L E++ + V N VV+
Sbjct: 1966 PDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVRGYRVELGEIESVILEHRQVRNAVVI- 2024
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++ N ++L + + + +++ L+ + +YMIP +++IE VP+ NGKV
Sbjct: 2025 NQKDARNQDVL-YAYVAGHQSLPPTDLKEFLSLKVPEYMIPSYIVQIEEVPLTSNGKV 2081
Score = 101 bits (241), Expect = 1e-20
Identities = 60/178 (33%), Positives = 101/178 (56%), Gaps = 3/178 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTH 197
++P G P+SN Y+L+ EN C G GE+ + G +A GY+ K+ H
Sbjct: 2958 SIPYGYPLSNQTYYVLNYENDPCPI-GVKGELFIGGKGVAEGYLNDKEK---TEASFIDH 3013
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+F ++YRTGD G+L +G I + GR D Q+K+RG+RV+L E++ + V N VV+
Sbjct: 3014 PDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVRGYRVELGEIESVILEHRQVRNAVVI- 3072
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
++ N ++L + + + +++ L+ + +YMIP +++IE VP+ NGKV
Sbjct: 3073 NQKDARNQDVL-YAYVAGHQSLPPTDLKEFLSLKVPEYMIPSYIVQIEEVPLTSNGKV 3129
>UniRef50_Q3M3K2 Cluster: Amino acid adenylation; n=2;
Nostocaceae|Rep: Amino acid adenylation - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 1093
Score = 101 bits (241), Expect = 1e-20
Identities = 64/181 (35%), Positives = 99/181 (54%), Gaps = 6/181 (3%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
++PIG PI+N+ VY+LD +++ V G GE+ + G LAR Y D RFI +P N+
Sbjct: 796 SIPIGRPIANSQVYILDSHLQPVPIGVTGELYIGGDGLAREYFHRPDLTAERFILHPFNS 855
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++LY++GD L G I Y GR D+QVK+ G R++L E++ A P V VV+
Sbjct: 856 DPQ-SRLYKSGDLARYLPDGEIEYLGRIDNQVKVSGFRIELGEIEIAFLQHPAVKEAVVV 914
Query: 372 C-YGVESSNPEILAFVTINPEARMS-AKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542
+ + FV + +S + L L +YM+P+V + +E +P+ NGK
Sbjct: 915 VREDIPGEKLLVGYFVAETGQDNLSIISELRQFLKQQLPEYMVPKVFMALEALPLNANGK 974
Query: 543 V 545
V
Sbjct: 975 V 975
>UniRef50_Q6WZB2 Cluster: Nonribosomal peptide synthetase; n=1;
Streptomyces vinaceus|Rep: Nonribosomal peptide
synthetase - Streptomyces vinaceus
Length = 2123
Score = 101 bits (241), Expect = 1e-20
Identities = 59/179 (32%), Positives = 100/179 (55%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
+PIG P N VY+LD+ +R V G GE+ V+G +ARGY+ RF+ +P+
Sbjct: 1405 LPIGRPFPNTRVYVLDDELRLVPRGTVGELYVSGAPVARGYLGRPALTADRFLPDPYG-- 1462
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +++YRTGD G +G++ + GR D QV++RGHR++ E++ + P V V +
Sbjct: 1463 PPGSRMYRTGDLGRFTGEGLLDFQGRGDFQVQLRGHRIEPGEIETVLCEQPGVTAAVAVV 1522
Query: 375 YGVESSN-PEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+S ++A+ E + + + A+L L YM+P V+ ++ +P+ VNGK+
Sbjct: 1523 RRPDSPEAAHLVAYAVRAEEPHGTDQALRAKLAERLPHYMVPTAVVTMDALPLTVNGKL 1581
Score = 83.8 bits (198), Expect = 2e-15
Identities = 55/179 (30%), Positives = 94/179 (52%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHNT 194
V +G P++ Y+LD+ MR + E GEV + G ++ RGY G+ RF+ +P+
Sbjct: 350 VLVGRPMAGATAYVLDDEMRRLAPNEVGEVYLGGASVTRGY-HGRAALTAQRFLPDPYG- 407
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++LYRTGD G + D G + GR D QVK+ G R++ E++ A++ P V +
Sbjct: 408 -PPGSRLYRTGDLGRVEDNGELRLLGRIDHQVKLHGRRIEPGEIEAAMTAHPHVSLAAAV 466
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
G + + F T A A+ + L L ++P +++ ++T+P+ NGK+
Sbjct: 467 PAGA-GAGATLTGFFT---GAEADAEELRGFLAQRLPAALVPSRLVALDTLPLSPNGKI 521
>UniRef50_Q5J1Q7 Cluster: NocA; n=1; Nocardia uniformis subsp.
tsuyamanensis|Rep: NocA - Nocardia uniformis subsp.
tsuyamanensis
Length = 3692
Score = 101 bits (241), Expect = 1e-20
Identities = 64/177 (36%), Positives = 90/177 (50%), Gaps = 3/177 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P N YLLD + V +G E+ +AG LARGY R G RF+ +P
Sbjct: 1447 VPIGGPTENTRAYLLDRYLAPVPDGVVAELYLAGSGLARGYSRRPGLTGERFLPDPFAGG 1506
Query: 198 PNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD + G + + GR D QVK+RGHR++L EV+ A++ P V VL
Sbjct: 1507 GQ--RMYRTGDLAVRRDGALHFIGRVDRQVKVRGHRIELDEVESALTAAPGVAEAAVLLR 1564
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
G ++A V PE + + A L L +M+P V+ + +P GKV
Sbjct: 1565 G-----GRLVAHVAAPPE--VDGAGLRAHLAGRLPAFMVPSVVVVSRALPRTSTGKV 1614
Score = 75.4 bits (177), Expect = 8e-13
Identities = 59/182 (32%), Positives = 92/182 (50%), Gaps = 8/182 (4%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
V +G P+ VYLLD + + V G GE+ + G LARGY+ G RF+ +P +
Sbjct: 2543 VSLGAPLPGARVYLLDPHGQPVPVGVVGELVLGGEVLARGYLGRPGATAERFLPDPFSDV 2602
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A+ YRTGD G + + GRAD QVKI G RV+ EV+ A+ P V C VL
Sbjct: 2603 PG-ARAYRTGDLARHRPDGGLEFVGRADRQVKILGVRVEPHEVETALVANPAVAACAVLP 2661
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTD----YMIP-QVIEIETVPVLVNG 539
++ ++ + + + AE+ +L + M+P +++ +E +PV G
Sbjct: 2662 REDARGAVGLVGYL-VPADRDADPGQLRAEVGRALRERLPRAMVPSRLVVLEALPVGPTG 2720
Query: 540 KV 545
K+
Sbjct: 2721 KL 2722
Score = 73.7 bits (173), Expect = 2e-12
Identities = 54/178 (30%), Positives = 86/178 (48%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+P+G P+ N V ++D + R G GE+ V G LARGY+ G+ RF+ +
Sbjct: 347 LPLGRPMHNAAVAVVDADGRRAPVGVAGELVVGGVPLARGYLGRPGETAARFVPDWLGLG 406
Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD L G I + GR D + K+RGHRVD E++ + P V V
Sbjct: 407 PAGGRVYRTGDRARRLPDGRIEFLGRVDDEFKVRGHRVDPAEIESLLHQHPLVGRAAVRL 466
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ ++A++ + + A L L +IP + + ++ P+ NGKV
Sbjct: 467 ----ADGAHVVAYL----QGSADPAELRAHLADRLPLAVIPTRWVRLDRFPLTPNGKV 516
>UniRef50_Q1IBI9 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Pseudomonas entomophila L48|Rep: Putative
non-ribosomal peptide synthetase - Pseudomonas
entomophila (strain L48)
Length = 1082
Score = 101 bits (241), Expect = 1e-20
Identities = 59/177 (33%), Positives = 96/177 (54%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200
PIG PI N +Y+LD ++ V G GE+ + G + +GY + + RFI +P + HP
Sbjct: 807 PIGRPIGNARLYVLDASLGRVPAGVVGEIHIGGLCVGQGYYKDPARTAERFIDDPFDNHP 866
Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LY+TGD G D G + GR D Q+K+RG R++ EV+ + P V+ +V+
Sbjct: 867 G-ARLYKTGDLGRWDAAGNLHMLGRCDFQLKVRGCRIEAGEVEAVLRQHPAVEQSLVVGA 925
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ +++A+V SA+++ A L DYM+P V ++ +L NGK+
Sbjct: 926 ADGNGQQQLVAYVIAPQRPAPSAQSLRAFCRQHLPDYMVPAAVCLLDAFDLLPNGKI 982
>UniRef50_Q1DCS5 Cluster: Non-ribosomal peptide synthetase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthetase - Myxococcus xanthus (strain DK 1622)
Length = 2108
Score = 101 bits (241), Expect = 1e-20
Identities = 61/176 (34%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
+P+G P+ N +++LDE G+ GE+C+AG ++RGY + PH HP
Sbjct: 336 IPLGRPVRNASMFVLDEAGGICPPGQLGELCIAGQGVSRGYHARPELTAQKFVPHPYHPG 395
Query: 204 FAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+ YRTGD G GV + GR D QVKIRG+RV+ +EV+ + + V+ VVL G
Sbjct: 396 -ARAYRTGDLGYQRSDGVFFFRGRVDRQVKIRGYRVEPEEVESRLQALEGVERAVVLPVG 454
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+S+ ++A V P A + L YM+P I + + P NGK+
Sbjct: 455 ANASSRRLVAHVVGRPGLEPVA--LRRMLARETPAYMLPSRIHVLDAFPRTPNGKI 508
Score = 100 bits (240), Expect = 2e-20
Identities = 65/177 (36%), Positives = 99/177 (55%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG P+++ ++D R + G PGE+C+AG +++ GY+ D RF+ PH HP
Sbjct: 1393 PIGRPMTHVEFLVVDPAGRMLGIGTPGELCIAGPSVSLGYLGRPDLTAERFV--PHPRHP 1450
Query: 201 NFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
++YRTGD G+L G + GRAD QVK+RG+RV+L E++ + P V VVL
Sbjct: 1451 G-ERMYRTGDLGVLRGDGNVALLGRADQQVKVRGYRVELGEIERVLLQHPDVHAGVVLLL 1509
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
G + ++ V PE ++ +E+ L + L YM+P Q + E+ P NGKV
Sbjct: 1510 G-SGAQATLVGCVIGVPEEALA--GLESWLAARLPHYMVPTQWLAQESFPASANGKV 1563
>UniRef50_Q1D593 Cluster: Non-ribosomal peptide synthetase; n=4;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Myxococcus xanthus (strain DK 1622)
Length = 4528
Score = 101 bits (241), Expect = 1e-20
Identities = 67/180 (37%), Positives = 97/180 (53%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
LTVPIG P+ N VY+LDE MR V G GE+ V G LA GYV + RF+ +P
Sbjct: 1858 LTVPIGKPVGNTRVYVLDEGMRPVPVGVRGELYVGGEGLAEGYVGRPEWTAERFVPSPFG 1917
Query: 192 THPNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
++YRTGD +G +L + GR D QVK+RG+R++L EV+ A+ V
Sbjct: 1918 ---EGERVYRTGDEVRWQEGGLLEFLGRRDEQVKVRGYRIELGEVEEALKQHAQVKEAAA 1974
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ G E + A+V + P A ++ + L +YM+P V+ + E +P+ NGKV
Sbjct: 1975 VVRG-EGQEKRVEAYV-VAPGGEGGA--LKEYVRQKLPEYMVPSVVVVLEALPLTPNGKV 2030
Score = 101 bits (241), Expect = 1e-20
Identities = 67/180 (37%), Positives = 97/180 (53%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
LTVPIG P+ N VY+LDE MR V G GE+ V G LA GYV + RF+ +P
Sbjct: 3972 LTVPIGKPVGNTRVYVLDEGMRPVPVGVRGELYVGGEGLAEGYVGRPEWTAERFVPSPFG 4031
Query: 192 THPNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
++YRTGD +G +L + GR D QVK+RG+R++L EV+ A+ V
Sbjct: 4032 ---EGERVYRTGDEVRWQEGGLLEFLGRRDEQVKVRGYRIELGEVEEALKQHAQVKEAAA 4088
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ G E + A+V + P A ++ + L +YM+P V+ + E +P+ NGKV
Sbjct: 4089 VVRG-EGQEKRVEAYV-VAPGGEGGA--LKEYVRQKLPEYMVPSVVVVLEALPLTPNGKV 4144
Score = 94.3 bits (224), Expect = 2e-18
Identities = 58/180 (32%), Positives = 94/180 (52%), Gaps = 4/180 (2%)
Frame = +3
Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191
+ VP+G P+ N VY+LD +R V G GE+ G + RGY+ + R++ +P+
Sbjct: 777 VVVPLGRPMGNTRVYVLDGGLRPVPVGVAGELYAGGAQVTRGYLGHPELTAERYVPDPYG 836
Query: 192 THPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
P A++YRTGD L G + + GR D QVK+RG RV+ EV + P V + VV
Sbjct: 837 GEPG-ARMYRTGDKVRWLADGRLEFIGRVDFQVKVRGFRVEPGEVATVLRAHPEVRDAVV 895
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ N ++A+ T + + + A L L +M+P ++ ++ +P+ NGKV
Sbjct: 896 VAREDVPGNKRLVAYATPSSQPAPDTAALRAFLQQRLPGHMVPSALVVLDALPLTPNGKV 955
Score = 90.2 bits (214), Expect = 3e-17
Identities = 57/179 (31%), Positives = 91/179 (50%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
TVP+G P+ N VY+LD ++R V G GE+ V G + RGYV + R++ +P +
Sbjct: 2919 TVPLGRPMGNTRVYVLDRSLRPVPVGVGGELFVGGAQVTRGYVWRPELTAERYVPDPFSM 2978
Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A++YRTGD L G + + GR D QVK+RG RV+ EV + P V + VV+
Sbjct: 2979 EAG-ARMYRTGDKVRWLGDGRLEFIGRTDFQVKVRGFRVEPGEVAAVLRAHPDVQDAVVV 3037
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++ + A + L L +M+P ++ ++ +P+ NGKV
Sbjct: 3038 AREEVPGDNRLVGYAVRTARAAPDIAALRGFLQQRLPGHMVPSALVVLDALPLTPNGKV 3096
>UniRef50_Q0S6F2 Cluster: Non-ribosomal peptide synthetase; n=2;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Rhodococcus sp. (strain RHA1)
Length = 6278
Score = 101 bits (241), Expect = 1e-20
Identities = 65/178 (36%), Positives = 91/178 (51%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG P+ N Y+LD +R V G GE+ + G LARGY D RF+ NP T
Sbjct: 2091 VPIGAPVWNTQTYVLDGRLRVVPVGVAGELYLGGVQLARGYQGRADLTADRFVANPFGT- 2149
Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD L G + Y GR D QVK+RG RV+L E++ + V VV+
Sbjct: 2150 ---GRLYRTGDRVRWLPSGELEYLGRTDFQVKLRGQRVELGEIEAVLLRREDVAQAVVVL 2206
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
G SS + +V A + + + +L +M+P V+ + +PV VNGK+
Sbjct: 2207 RGDGSSGEYLAGYVVPVAGAVVDERVVRESAAVALPGFMVPSVVVVLAELPVTVNGKL 2264
Score = 79.4 bits (187), Expect = 5e-14
Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 5/179 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+ IG PI +LD ++ V G PGE+ +AG LARGY R RF+ +P
Sbjct: 4685 ITIGGPIRGVTELVLDPRLQPVPVGVPGELYLAGAGLARGYHRRPALTAERFVAHP--VR 4742
Query: 198 PNFAKLYRTGDF--GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD D+ I Y GR D QVK+RG R++L E+D + + P V L
Sbjct: 4743 PG-ERMYRTGDIVRWTADRS-IEYVGRTDFQVKVRGFRIELGEIDSTLMSEPDVGFAATL 4800
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ + + ++++V + + L L +M+P I + E +P+ GK+
Sbjct: 4801 AHRGPAGDTLLVSYVVPASGRSLDPVVLTRHLADRLPSHMVPTSITVLERIPLTAVGKL 4859
Score = 77.0 bits (181), Expect = 3e-13
Identities = 54/180 (30%), Positives = 90/180 (50%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHN 191
T+ +G P+ + +LD ++ V G GE+ VAG LARGY GK RF+ NP
Sbjct: 1025 TITVGGPLRGFHEVVLDARLQPVPPGVAGELYVAGDGLARGY-HGKSALTAERFVANPFG 1083
Query: 192 THPNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
P ++YRTGD + L Y GR D QVKIRG R++ E+D + P V +
Sbjct: 1084 G-PG-ERMYRTGDVVRWRTDLSLEYLGRIDFQVKIRGFRIEPGEIDTVLHAHPRVRTAMT 1141
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ S + ++++V +++ + + L YM+P ++ ++ +P+ GK+
Sbjct: 1142 MPRTAPSGDTVLVSYVLPAAGHQLATRELIDYAAEQLPTYMVPAAIVVLDEIPMTPVGKL 1201
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/180 (27%), Positives = 86/180 (47%), Gaps = 5/180 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
+V IG P +LDE ++ V G PGE+ +AG +ARGY RF+ N
Sbjct: 5742 SVNIGAPARGFAFLVLDERLQPVPVGVPGELYIAGPGMARGYHNRAALTSERFV--ACNF 5799
Query: 195 HPNFAKLYRTGDFGILDKGV--ILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368
++YRTGD + + Y GR+D QVK+RG R++L E+D ++ P V
Sbjct: 5800 GEPGCRMYRTGDVVRWRESASALEYIGRSDFQVKVRGFRIELGEIDAVLTRHPAVAFAAT 5859
Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ + S + + ++V + + + L +M+P V+ ++ +P+ GK+
Sbjct: 5860 IGHIGPSGDTVLASYVRAQDGQEVQPAGLRTYASERLPAHMVPSAVVVLDRIPMTPVGKL 5919
Score = 70.5 bits (165), Expect = 2e-11
Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHPN 203
IG + VY+LD + V G GE+ V+G ++RGY+ RF+ +P P
Sbjct: 3168 IGRGLPGLRVYVLDGRLHPVPPGVVGEMYVSGAQVSRGYLGRAALTSGRFVADPFT--PG 3225
Query: 204 FAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A++YR+GD G + G + Y GR D QV+++G+R++L EV+ A+ V VV G
Sbjct: 3226 -ARMYRSGDLGRWNGHGQLEYLGRNDLQVQVKGYRIELGEVEAALLACEGVAQSVVTARG 3284
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ +V A + I L +M+P V+ ++ +P VNGK+
Sbjct: 3285 -----DRLVGYVVPETGAAIDPAAIIDAAAVRLASHMVPAAVVVLDELPRTVNGKL 3335
>UniRef50_A5FI38 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain -
Flavobacterium johnsoniae UW101
Length = 3395
Score = 101 bits (241), Expect = 1e-20
Identities = 59/178 (33%), Positives = 100/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PISN VY+L++ + G GE+C++G +L+ GY+ ++ +FI NP +
Sbjct: 3112 VPIGKPISNVQVYILNDKLNMQPVGVIGELCISGESLSNGYLNNEELTNEKFIENPFKSG 3171
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
K+Y+TGD L G I + GR D QVKIRG+R++L E++ + + + + VVL
Sbjct: 3172 ---QKIYKTGDLARWLPDGNIEFMGRIDGQVKIRGYRIELGEIEKQLLSQEGIKHSVVLV 3228
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
++ + +V+ + + K + L+ L DYMIP ++++ +P+ N KV
Sbjct: 3229 KEIKGEKCLVAYYVS---DYELDKKILTENLSKMLPDYMIPAYYVQLDVIPLTTNDKV 3283
Score = 87.4 bits (207), Expect = 2e-16
Identities = 51/173 (29%), Positives = 92/173 (53%), Gaps = 4/173 (2%)
Frame = +3
Query: 39 PISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNTHPNFAK 212
PI N V++LDEN V G GE+ +AG + RGY + F++ P N +
Sbjct: 581 PIQNFEVHILDENRERVPVGVKGEIYLAGPCVGRGYFNDEKRTKEAFLNGPIEGITNQKR 640
Query: 213 LYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVES 389
+Y+TGD + G + + GR D+QVKI GHR++L +++ ++ IP V + +
Sbjct: 641 IYKTGDLARFMPNGTMEFIGRNDNQVKILGHRIELDAIENIMAEIPAVKS----VKAIAD 696
Query: 390 SNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+N +++ ++ ++ + +E +L + L YM+P I + + P+ NGK+
Sbjct: 697 TNKQMIVLYYVS-DSEIDKNFMEEQLLNKLPKYMLPSAFIHMLSFPLTKNGKI 748
Score = 85.0 bits (201), Expect = 1e-15
Identities = 60/176 (34%), Positives = 90/176 (51%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG PI +LDE V G GE+ + G LARGY+ + RFI NP N
Sbjct: 1624 IGKPIPTLSCLILDEFKNIVPAGVIGEMYIGGSGLARGYLNRPELTAERFIVNPFNPEE- 1682
Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LY+TGD G G I Y GR D+QVKIRGHR++L E++ AV D +
Sbjct: 1683 --RLYKTGDLGRWQTDGNIEYIGRIDNQVKIRGHRIELGEIE-AVLLGYSSDIRQFVVDT 1739
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E + +IL ++ + + ++ + + L +YM+P + ++ +P+ NGKV
Sbjct: 1740 CELNGDKILVAYYVS-DTEVDKASLRSYIQQQLPEYMVPNFFVAMDAIPLTGNGKV 1794
>UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Putative
non-ribosomal peptide synthetase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 2385
Score = 101 bits (241), Expect = 1e-20
Identities = 66/179 (36%), Positives = 97/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNT 194
+V IG P N +Y+LDE+++ V G GE+ VAG L RGYV RF+ +P
Sbjct: 1844 SVSIGRPNPNTRMYVLDEHLQPVPVGVQGELYVAGLQLGRGYVNAPALTASRFVADPFG- 1902
Query: 195 HPNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++YRTGD G L + GRAD QVKIRG RV+LQEV+ +S P V VV+
Sbjct: 1903 -PAGERMYRTGDLACWTAGGTLEFRGRADHQVKIRGMRVELQEVESVLSEHPAVRQAVVV 1961
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
S ++A+ T E+ ++ + L L ++M+P V+ + P++ +GKV
Sbjct: 1962 TARSRSDVGLLVAYCTTTDES-VTGDGLRGWLRGRLPEHMVPAAVVCLPRFPLMPSGKV 2019
Score = 90.2 bits (214), Expect = 3e-17
Identities = 62/179 (34%), Positives = 94/179 (52%), Gaps = 7/179 (3%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG + YLLDE +R V +G GE+ V G LARGY+ G RF+ +P P
Sbjct: 787 IGRGLPGLSTYLLDEALRPVPDGVVGELYVGGAQLARGYLGRPGLTATRFVADPFGA-PG 845
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LYRTGD G + Y GRAD QVKIRG R++ E+ ++T P V C V+
Sbjct: 846 -ERLYRTGDLARRAGDGRLEYVGRADDQVKIRGFRIEPAEISSVLATHPDVSRCAVVARH 904
Query: 381 VESSNPEILAFV---TINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ +V +++P A + L + L ++M+P +E+E++P+ NGK+
Sbjct: 905 GAQGGAYLVVYVVGESVDPAA------LRGYLAARLPEHMVPAAFVELESLPLTGNGKL 957
>UniRef50_A0V6U3 Cluster: Amino acid adenylation domain; n=1; Delftia
acidovorans SPH-1|Rep: Amino acid adenylation domain -
Delftia acidovorans SPH-1
Length = 4560
Score = 101 bits (241), Expect = 1e-20
Identities = 61/178 (34%), Positives = 100/178 (56%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+PIG P++ +++++D+ MR V G GE+C+ G L+RGY+ G RF+ +P H
Sbjct: 2495 LPIGRPLAGRHMWVVDDRMRPVPLGVAGELCIGGPLLSRGYLNRAGLSAERFVADPFG-H 2553
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
A+LYRTGD + +G + Y GR D QVKIRG R++L EV + + V VV+
Sbjct: 2554 DG-ARLYRTGDLVRWNAQGQLEYLGRVDHQVKIRGLRIELGEVQAQLLALDDVREAVVVA 2612
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
G + +LA+V+ + + + L + L DYM+P ++ ++ +P NGK+
Sbjct: 2613 -GEGPAGTRLLAYVSARSGRTLDEQEMRERLATVLPDYMVPGAIMVLDQLPQNANGKL 2669
Score = 100 bits (240), Expect = 2e-20
Identities = 64/179 (35%), Positives = 97/179 (54%), Gaps = 6/179 (3%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHP 200
PIG P+ V++LD ++ V G GE+ + G+ LARGY+ G RF+ +P +
Sbjct: 4005 PIGRPVGERTVHILDADLHRVPHGVVGELYIGGYGLARGYLSRHGLTAERFVADPFDG-- 4062
Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+LYRTGD + G I Y GRAD QVKIRG R++L EV+ AV +P V + VL
Sbjct: 4063 GGGRLYRTGDLVREMPDGNIEYIGRADHQVKIRGFRIELGEVEKAVRAVPGVVDAAVLVQ 4122
Query: 378 GVESSNPEILAFVT--INPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ +++A+V A+ + I + L DYM+P + + +P LV+GK+
Sbjct: 4123 DA-GTGKQLVAYVVGEEGTAAQTLVQRIRQQTGEHLPDYMLPAHTLVLPALPRLVSGKL 4180
Score = 91.9 bits (218), Expect = 9e-18
Identities = 59/178 (33%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P+S +L +++ V G GE+ + G LA+GY+ G RF+ +P +
Sbjct: 311 VPIGRPVSATKALVLGQDLGLVPAGVAGELYLGGQALAQGYLGRPGLSAERFVADPFDQ- 369
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD D+G + Y GR D QVKIRG R++L E++ + P V VV+
Sbjct: 370 -GGGRLYRTGDLVRWNDEGQLEYLGRLDHQVKIRGFRIELGEIEARLLAQPQVRESVVVA 428
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ + A+V+ + +++A + L L DYM+P ++ ++ +P+ NGKV
Sbjct: 429 -RKGPAGMHLAAYVSAHEGQQVTAAELRERLALELPDYMVPASIMVLDRLPLNANGKV 485
Score = 91.5 bits (217), Expect = 1e-17
Identities = 66/181 (36%), Positives = 94/181 (51%), Gaps = 7/181 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG PIS Y+LD MR +G GE+ + G LARGY+ RF+ +P +T
Sbjct: 1396 VPIGQPISGIRTYVLDCAMRPAPQGVAGELYLGGIGLARGYLNRPALTAERFVADPLDTQ 1455
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
LYRTGD + +G I Y GR D QVKIRG R++L E++ + P V VV+
Sbjct: 1456 GGL--LYRTGDLVRWNGEGQIEYLGRLDHQVKIRGLRIELGEIEAHLLAQPGVREAVVVA 1513
Query: 375 YGVES--SNPEILAFVTINPEARMS-AKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542
S + ++A+V P+A A+ + L L DYM P ++ + + + NGK
Sbjct: 1514 AQATSGAAGARLVAYVA-GPDADAGLAETLRQALAGRLPDYMQPSAIVVLPALALNANGK 1572
Query: 543 V 545
V
Sbjct: 1573 V 1573
>UniRef50_Q5YPH6 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Nocardia farcinica|Rep: Putative non-ribosomal
peptide synthetase - Nocardia farcinica
Length = 5961
Score = 100 bits (240), Expect = 2e-20
Identities = 61/181 (33%), Positives = 99/181 (54%), Gaps = 7/181 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P+ N +++LD +R V G PGE+ ++G LARGYV G RF+ +P
Sbjct: 840 VPIGAPVFNTRLHVLDSRLRPVPVGAPGELYLSGVQLARGYVARPGLSAERFVADPFG-- 897
Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P ++YRTGD + G + Y GR D QVK+RG R++L E++ ++ + V VVL
Sbjct: 898 PAGTRMYRTGDLVRWNTSGELEYLGRTDFQVKLRGLRIELGEIEAVLAGVDGVVRAVVLV 957
Query: 375 ---YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542
G + +++A+V + A+ + A +L YM+P + ++ +PV +GK
Sbjct: 958 RDDVGSPALGEQLVAYVVAAEPDAVGAEQLRAAALRALPAYMVPAAYVVLDELPVNASGK 1017
Query: 543 V 545
+
Sbjct: 1018 L 1018
Score = 93.1 bits (221), Expect = 4e-18
Identities = 60/179 (33%), Positives = 98/179 (54%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194
+VPIG P++N VY+LD+ +R V G PGE+ +AG LARGY D RF+ +P
Sbjct: 2965 SVPIGSPVANTRVYVLDDRLRPVPAGVPGELYLAGVQLARGYAGRPDLTADRFVADPFT- 3023
Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P A++YRTGD G + Y GR D QVK+RG R++ E++ A++ + VD VV+
Sbjct: 3024 -PG-ARMYRTGDRVRWSAAGELEYLGRTDFQVKVRGMRIEPGEIEAALTELDGVDQAVVV 3081
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ + ++A++ P + + L L Y++P + ++ P+ +GK+
Sbjct: 3082 -----ARDEHLVAYLI--PAGPVDPDAVRVALARRLPAYLVPAAFVLLDAFPLNASGKL 3133
Score = 89.4 bits (212), Expect = 5e-17
Identities = 62/181 (34%), Positives = 99/181 (54%), Gaps = 7/181 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197
V IG P+ ++LDE +R V G GE+ VAG LARGY R RF+ P
Sbjct: 1905 VTIGRPLRGVREWVLDERLRPVPVGVAGELYVAGAQLARGYHGRRATTAERFVACPWA-- 1962
Query: 198 PNFAKLYRTGDF--GILDKG--VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
P ++YRTGD L G + Y GR D+QVK+RG R++L E++ A++ P V + V
Sbjct: 1963 PG-ERMYRTGDLVRWTLASGGRELEYLGRNDAQVKVRGFRIELGEIEAALAARPGVAHAV 2021
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGK 542
V + + ++ A+V + + A +++A L + L +++P I + +T+P+ NGK
Sbjct: 2022 VTVHRDPARGDQLAAYVVPSGGHPLDAGDLKAGLRTRLAPHLVPAAITVLDTLPLTPNGK 2081
Query: 543 V 545
+
Sbjct: 2082 L 2082
Score = 87.0 bits (206), Expect = 2e-16
Identities = 59/177 (33%), Positives = 93/177 (52%), Gaps = 5/177 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHPN 203
IG I V +LD +R V G PGE+ V+G LARGY+ G RF+ +P+ P
Sbjct: 4035 IGGAIPGLTVRVLDPRLRPVPVGVPGEIYVSGGQLARGYLGRPGLTAGRFVADPYG--PA 4092
Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
A+ YR+GD G + + GRAD QV +RG R++L E++ A+ P V V+
Sbjct: 4093 GARAYRSGDLARWTATGELEFLGRADQQVNLRGFRIELGEIEAALLAEPEVTEAAVVVRS 4152
Query: 381 VESSNPEILAF-VTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
I+ + VT P + + + +L ++M+P ++EI+ +P+ VNGK+
Sbjct: 4153 DLVDEARIVGYLVTAGP---VDTAELRERVRRTLPEHMVPAALVEIDRIPLTVNGKL 4206
Score = 79.8 bits (188), Expect(2) = 2e-16
Identities = 50/138 (36%), Positives = 75/138 (54%), Gaps = 3/138 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNT 194
TVPIG P N+ +Y+LD MR V G GE+ +AG LARGY RF+ +P +
Sbjct: 5089 TVPIGTPAWNSRLYVLDRRMRPVPVGVAGELYLAGVQLARGYQAAPALTAGRFVADPFD- 5147
Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
A++YRTGD G + Y RAD QVKI G R++L +++ A+ +P V V L
Sbjct: 5148 --RGARMYRTGDIVRRRADGSLEYLERADFQVKIGGFRIELGDIESALLALPGVRAAVAL 5205
Query: 372 CYGVESSNPEILAFVTIN 425
++ ++A+ ++
Sbjct: 5206 ARTDGAAGARLVAYAAVD 5223
Score = 27.9 bits (59), Expect(2) = 2e-16
Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Frame = +3
Query: 444 AKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
A + AEL L YM+P V+ + +P+ NGKV
Sbjct: 5258 AAELRAELRERLPGYMVPAAVMALPALPLTGNGKV 5292
>UniRef50_Q47NR9 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Thermobifida fusca YX|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Thermobifida fusca (strain YX)
Length = 3629
Score = 100 bits (240), Expect = 2e-20
Identities = 61/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V IGVP++N VY+LD +R V G GE+ +AG +A GY D RF+ +P+
Sbjct: 2284 VTIGVPMANTRVYVLDAGLRLVPPGVAGELYIAGEGVAWGYHGRFDLTAQRFVADPYG-- 2341
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +++YRTGD G + + GRAD QVKIRG RV+L E++ A++ I + VV+
Sbjct: 2342 PPGSRMYRTGDVVRWRSDGRLDFLGRADFQVKIRGFRVELGEIETALARIDGISQAVVVA 2401
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ ++A++ A I +L + L YM+P + ++ P+ NGK+
Sbjct: 2402 RNDSGNHQRLVAYLVPAGAAAPGTAEIREKLAAVLPAYMVPSAFVVVDEFPLTANGKI 2459
Score = 99.5 bits (237), Expect = 4e-20
Identities = 60/178 (33%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
V IGVP++N VY+LD +R V G GE+ +AG +A GY D RF+ +P+
Sbjct: 3330 VTIGVPMANTRVYVLDAGLRLVPPGVAGELYIAGEGVAWGYHGRFDLTAQRFVADPYG-- 3387
Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P +++YRTGD G + + GRAD QVKIRG RV+L E++ A++ I + VV+
Sbjct: 3388 PPGSRMYRTGDVVRWRSDGRLDFLGRADFQVKIRGFRVELGEIETALARIDGISQAVVVA 3447
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
++ ++ +V E ++ + + L +L YM+P + ++ P+ NGK+
Sbjct: 3448 RNDSGNHQRLVGYVV--AERLVTPRELRTALAETLPAYMVPSAFVVVDEFPLTANGKI 3503
Score = 97.1 bits (231), Expect = 2e-19
Identities = 57/179 (31%), Positives = 95/179 (53%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194
T +G P+ V +LD+ ++ V G GE+ +AG +ARGY+ D RF+ +P+
Sbjct: 767 TPTVGRPVPGVAVRILDDALQPVPVGVAGELYLAGVQVARGYLGRPDQTADRFVADPYG- 825
Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P +++YRTGD G + Y GR D+Q+++RG RV+++E++ T P V C V
Sbjct: 826 -PPGSRMYRTGDRVRQRADGQLEYLGRVDTQLQVRGFRVEVEEIEAVAETHPAVARCAVA 884
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+ S + + A V ++ ++ + A L L D M+P V+ +PV NGK+
Sbjct: 885 AHTAASGSVRLSAHVVLHQGVTLTPDQLRAHLAEHLPDAMVPAAVVFTSDLPVTPNGKL 943
>UniRef50_Q5IW58 Cluster: Phosphinothricin tripeptide synthetase II;
n=2; Streptomyces viridochromogenes|Rep: Phosphinothricin
tripeptide synthetase II - Streptomyces viridochromogenes
Length = 1086
Score = 100 bits (240), Expect = 2e-20
Identities = 63/178 (35%), Positives = 97/178 (54%), Gaps = 5/178 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
P+G P++ V++LD+ +R V G GE+ + G LARGY+ D RF+ +P T P
Sbjct: 810 PLGRPVAGYTVHVLDDTLRPVPFGRQGELFLGGVGLARGYLDQPDVTADRFLPDPSGTEP 869
Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A+LYRTGD G + + GR D QVK+RG R++L E++ + P V VVL
Sbjct: 870 G-ARLYRTGDVVRWGADGELEFLGRTDHQVKLRGFRIELGEIETRLEDHPGVRTAVVLVR 928
Query: 378 GVESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
G E S+ + + P E R +A + L L YM+P++ + ++ +P NGK+
Sbjct: 929 G-EGSDRRLAGYAVRAPGEERPTAAGLRQWLRDRLPGYMVPELFLVLDALPTSPNGKL 985
>UniRef50_Q5DIV7 Cluster: PvdI; n=5; Pseudomonas aeruginosa|Rep: PvdI
- Pseudomonas aeruginosa
Length = 5155
Score = 100 bits (240), Expect = 2e-20
Identities = 66/178 (37%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG PI+N Y+LD N+ V G GE+ +AG LARGY + G RF+ +P
Sbjct: 3356 VPIGRPIANLACYILDGNLEPVPVGVLGELYLAGQGLARGYHQRPGLTAERFVASPFVAG 3415
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD GVI YAGR D QVK+RG R++L E++ + P V VL
Sbjct: 3416 ---ERMYRTGDLARYRADGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHPWVREAAVLA 3472
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+++ +V + E+ + + A L +SL +YM+P Q + +E +P+ NGK+
Sbjct: 3473 V----DGKQLVGYVVLESESGDWREALAAHLAASLPEYMVPAQWLALERMPLSPNGKL 3526
Score = 99.5 bits (237), Expect = 4e-20
Identities = 66/178 (37%), Positives = 97/178 (54%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG PI+N Y+LD N+ V G GE+ +AG LARGY + G RF+ +P
Sbjct: 829 VPIGRPIANLACYILDGNLEPVPVGVLGELYLAGQGLARGYHQRPGLTAERFVASPFVAG 888
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
++YRTGD GVI YAGR D QVK+RG R++L E++ + P V VL
Sbjct: 889 ---ERMYRTGDLARYRADGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHPRVREAAVLA 945
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
+++ +V + E + + A L +SL +YM+P Q + +E +P+ NGK+
Sbjct: 946 V----DGRQLVGYVVLESEGGDWREALAAHLATSLPEYMVPAQWLALERMPLSPNGKL 999
Score = 81.0 bits (191), Expect = 2e-14
Identities = 58/187 (31%), Positives = 97/187 (51%), Gaps = 13/187 (6%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
+PIG + N Y+LD + + G GE+ + G +ARGY+ RF+ +P
Sbjct: 4859 MPIGTLLGNRSGYILDGQLNLLPVGVAGELYLGGEGVARGYLERPALTAERFVPDPFGA- 4917
Query: 198 PNFAKLYRTGDF--GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
P ++LYR+GD G D GV+ Y GR D QVKIRG R++L E++ + P V VV+
Sbjct: 4918 PG-SRLYRSGDLTRGRAD-GVVDYLGRVDHQVKIRGFRIELGEIEARLREHPAVREAVVV 4975
Query: 372 CYGVESSNPEILAFVTI-------NPEARMSAK-NIEAELTSSLTDYMIP-QVIEIETVP 524
+ +++ +V +PEA+ + ++ L L +YM+P ++ + +P
Sbjct: 4976 AQ-PGAVGQQLVGYVVAQEPAVADSPEAQAECRAQLKTALRERLPEYMVPSHLLFLARMP 5034
Query: 525 VLVNGKV 545
+ NGK+
Sbjct: 5035 LTPNGKL 5041
Score = 68.1 bits (159), Expect = 1e-10
Identities = 54/180 (30%), Positives = 88/180 (48%), Gaps = 8/180 (4%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203
IG + +LD ++ G GE+ + G LARGY+ G+ RF+ +P +
Sbjct: 2306 IGRALGARRACILDAALQPCAPGMIGELYIGGQCLARGYLGRPGQTAERFVADPFSGSGE 2365
Query: 204 FAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LYRTGD G + Y GRAD Q+KIRG R+++ E++ + P V V+
Sbjct: 2366 --RLYRTGDLARYRVDGQVEYLGRADQQIKIRGFRIEIGEIESQLLAHPYVAEAAVVAQ- 2422
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAE----LTSSLTDYMIPQVIEI-ETVPVLVNGKV 545
+ +LA + +A M +++ AE L L YM P ++ ++P+ NGK+
Sbjct: 2423 -DGVGGPLLAAYLVGRDA-MRGEDLLAELRTWLAGRLPAYMQPTAWQVLSSLPLNANGKL 2480
>UniRef50_Q4H1C8 Cluster: Non-ribosomal peptide synthetase B; n=1;
Actinoplanes friuliensis|Rep: Non-ribosomal peptide
synthetase B - Actinoplanes friuliensis
Length = 3143
Score = 100 bits (240), Expect = 2e-20
Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197
VPIG P+ N +Y+LD ++ V G GE+ + G LARGYV G RF+ +P+
Sbjct: 745 VPIGRPLPGNRLYVLDPALQPVPAGATGELYIGGTGLARGYVNRPGLTGQRFVADPY-AG 803
Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P A++YR+GD L G + Y GR D QVKIRG+RV+ E++ +++ V C V+
Sbjct: 804 PG-ARMYRSGDLARLRADGNLEYLGRIDDQVKIRGYRVEPGEIEAVLASADQVARCAVVV 862
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
+ ++A+V + + + + A L + L YM+P ++ ++ +P NGKV
Sbjct: 863 REDRPGDQRLVAYV-VAADGTVDPSALTAHLAARLPAYMVPSAIVGLDELPWTANGKV 919
Score = 94.3 bits (224), Expect = 2e-18
Identities = 60/182 (32%), Positives = 96/182 (52%), Gaps = 7/182 (3%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194
T PIG P+ N V++LD ++ V G PGE+ V G LARGY+ G+ RF+ +P
Sbjct: 2363 TAPIGRPLWNATVFVLDARLQPVPLGAPGELYVGGAQLARGYLNRPGRTAERFVASPFGA 2422
Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+ +LYRTGD + G + + GR D QVKI G RV+ EV+ ++ P V VV+
Sbjct: 2423 PGD--RLYRTGDLVRWTRDGELQFLGRGDHQVKIGGFRVEPGEVEGVLAAHPGVTTAVVV 2480
Query: 372 CYGVESSNPEILAFVTINPEARM---SAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539
++A+ +P+ + + + A L L Y++P V+ ++ +P+ NG
Sbjct: 2481 PRDDLPGGTRLVAYAVPDPQHDLGPDGGRRLRAHLEEHLPSYLVPAAVVLLDVLPLTPNG 2540
Query: 540 KV 545
K+
Sbjct: 2541 KL 2542
>UniRef50_A5YBV1 Cluster: Fusaricidin synthetase; n=1; Paenibacillus
polymyxa|Rep: Fusaricidin synthetase - Paenibacillus
polymyxa (Bacillus polymyxa)
Length = 2564
Score = 100 bits (240), Expect = 2e-20
Identities = 64/176 (36%), Positives = 92/176 (52%), Gaps = 4/176 (2%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203
IG I Y+LDE R G PGE+ +AG LARGY+ D +F+ +P+
Sbjct: 776 IGRTIPTLSAYILDEQRRLQPVGVPGELYIAGDGLARGYLNRPDLTSEKFVEHPYRVGE- 834
Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380
+LYRTGD L G I Y GR D QVKIRG+R++L EV+ + P V +VL
Sbjct: 835 --RLYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKAPSVRETIVLARE 892
Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E + A+ + + +S + A+L + L YMIP + +E +P+ NGK+
Sbjct: 893 DEQGQKLLCAYYVASSD--LSPGELRAQLAAELPAYMIPSYFVPLEQMPLTPNGKL 946
Score = 89.0 bits (211), Expect = 6e-17
Identities = 57/178 (32%), Positives = 96/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI N+ Y+++ +++ G GE+ V G +ARGY+ D +F+ +P
Sbjct: 1808 VPIGRPIRNSTAYVVNGSLQLQPIGAWGELIVGGEGVARGYLNRPDLTAEKFVPSPVK-- 1865
Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+ YRTGD L G + + GR D QVKIRG+R++L E++ ++ + V + VV+
Sbjct: 1866 -DGEPCYRTGDLVRWLPDGNLEFKGRIDEQVKIRGYRIELPEIEAQLAKVESVIDAVVVV 1924
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545
E ++ A+ + ++A + L+ L YMIP I+++ +P+ NGKV
Sbjct: 1925 RADELGEKQLCAYYV--ADRTLTAGEVRLSLSQVLPGYMIPSYFIQMDRMPLTSNGKV 1980
>UniRef50_Q8YTR9 Cluster: Peptide synthetase; n=2; Nostocaceae|Rep:
Peptide synthetase - Anabaena sp. (strain PCC 7120)
Length = 2617
Score = 100 bits (239), Expect = 3e-20
Identities = 64/178 (35%), Positives = 97/178 (54%), Gaps = 6/178 (3%)
Frame = +3
Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY-VRGK-DPHRFIHNP--HNTH 197
IG PI+N VY+LD+N++ V G PGE+ ++G LARGY R K RFI ++
Sbjct: 1840 IGQPIANTQVYILDQNLQPVPVGIPGEIYLSGAGLARGYWKRPKLTDERFIKQSTVNSQQ 1899
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
LY+TGD L G I Y GR D QVK+RG R++L E++ + P + V +
Sbjct: 1900 STVNTLYKTGDRARYLPDGNIEYLGRFDHQVKLRGFRIELGEIEALLHQHPELTQAVAIV 1959
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V P++ + A + L + L YM+P + +ET+P+ NGKV
Sbjct: 1960 RNDTPEHSRLVAYVV--PKSHIEAAELRQFLAAKLPAYMLPTAFVILETLPLTANGKV 2015
Score = 97.1 bits (231), Expect = 2e-19
Identities = 60/181 (33%), Positives = 98/181 (54%), Gaps = 7/181 (3%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP---H 188
V IG PI+N Y+LDE+++ V G PGE+ + G +A+GY + D RF++ +
Sbjct: 794 VTIGHPIANTQFYVLDEHLQPVPIGVPGELYIGGAGVAKGYWQRPDLTAERFLNQQSTVN 853
Query: 189 NTHPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365
+ LY+TGD L G + Y GR D QVKIRG R++L E++ ++ P + V
Sbjct: 854 SQQSTVNTLYKTGDRVRYLPDGKLEYLGRLDYQVKIRGFRIELGEIEAVLAQHPQISQAV 913
Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542
V E ++A++ N + + + +++ L + L YMIP V + + +P+ NGK
Sbjct: 914 VSVQEDEPGEQRLVAYIVPNSQ-DVGSNDLQQFLANKLPKYMIPGVFVTLTALPLTPNGK 972
Query: 543 V 545
V
Sbjct: 973 V 973
>UniRef50_Q4ZVI3 Cluster: Amino acid adenylation; n=3;
Pseudomonas|Rep: Amino acid adenylation - Pseudomonas
syringae pv. syringae (strain B728a)
Length = 3021
Score = 100 bits (239), Expect = 3e-20
Identities = 64/177 (36%), Positives = 98/177 (55%), Gaps = 4/177 (2%)
Frame = +3
Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200
PIG PI+N +Y+LD ++ V G GE+ +AG LARGY+ D RF+ +P N
Sbjct: 1423 PIGRPIANARLYVLDGDLNPVPVGVAGELYIAGACLARGYLNRPDLSAERFLPDPFNPQS 1482
Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
A++YR+GD G + Y GR D QVK+RG RV+L E+D + P V VVL
Sbjct: 1483 G-ARMYRSGDLARFAADGNVHYLGRIDQQVKLRGFRVELGEIDSLLHQQPGVREAVVLLR 1541
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545
+ ++A+V + P +A+ + AEL L ++M+P + + +P+ NGK+
Sbjct: 1542 EDVPGDKRLVAYV-VGP---ATAETLRAELHRHLPEHMVPTAWVALAQLPLTRNGKL 1594
Score = 94.3 bits (224), Expect = 2e-18
Identities = 59/183 (32%), Positives = 97/183 (53%), Gaps = 4/183 (2%)
Frame = +3
Query: 9 HIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN 182
H+ +PIG ++N +YLLD V +G GE+ + G +ARGY+ + RFI +
Sbjct: 346 HVDAVLPIGRALANTRIYLLDAAGDRVPQGVTGELYIGGAGVARGYLNLPELTRERFIDS 405
Query: 183 PHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359
P +LYRTGD G + + GR DSQ K+RG R++L E++ ++ + V +
Sbjct: 406 PFVAGD---RLYRTGDLARYRADGHLEFLGRNDSQAKLRGLRLELGEIEARLAEVAGVRD 462
Query: 360 CVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536
VV+ + P ++A+ A ++ K + L SL DYMIP + ++ +P+ N
Sbjct: 463 NVVVLREDGAGVPRLIAYFREQTGAALTPKGLRQHLQLSLPDYMIPAAFVRMDALPLTAN 522
Query: 537 GKV 545
GK+
Sbjct: 523 GKL 525
Score = 84.2 bits (199), Expect = 2e-15
Identities = 55/178 (30%), Positives = 90/178 (50%), Gaps = 3/178 (1%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200
++P G + + Y+LD+ ++ G++ + G LA+GY R + HP
Sbjct: 2483 SIPYGKALDHQRFYVLDDALQVRPTWVAGQLYIGGIGLAKGYWRDE---ALSAGSFFAHP 2539
Query: 201 -NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
+LYRTGD G L G I + GR D+QVK++GHR++L E++ A++ P V + VV
Sbjct: 2540 LTGERLYRTGDLGRWLPDGNIEFLGREDTQVKVQGHRIELGEIEAALNRHPGVQSAVVRV 2599
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545
G E+ + LA + + + A + L L YM+P ++ P+ NGKV
Sbjct: 2600 LG-EALGEKRLAGYVLKADPSLQASDFVQYLADKLPAYMLPTSFTFVQEWPLSANGKV 2656
>UniRef50_Q311J0 Cluster: Amino acid adenylation; n=2; Bacteria|Rep:
Amino acid adenylation - Desulfovibrio desulfuricans
(strain G20)
Length = 3252
Score = 100 bits (239), Expect = 3e-20
Identities = 62/179 (34%), Positives = 94/179 (52%), Gaps = 4/179 (2%)
Frame = +3
Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNT 194
TVP G P+ N + +LDE + GE+ + G LA GY+ K +FI +P
Sbjct: 1901 TVPYGTPLPNQKLMVLDEQLEIAPAWVTGELHIGGKGLALGYLNDPEKTAAQFIRHPRTG 1960
Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371
+LY+TGD G L G I + GR D+QVKIRGHRV+ E++H + P V V+
Sbjct: 1961 E----RLYKTGDLGRYLPDGTIEFIGRKDAQVKIRGHRVEPGEIEHCLLRHPAVHKAAVI 2016
Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
G ++ P LA + + + A L S+L ++M+P Q+I + +P+ NGK+
Sbjct: 2017 AVG-DAGKPRSLAAFVVT----TAHDELRAFLRSNLPEHMVPSQIIAVPALPLTENGKL 2070
Score = 99.5 bits (237), Expect = 4e-20
Identities = 57/177 (32%), Positives = 96/177 (54%), Gaps = 3/177 (1%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203
+P G P++N +++L+ + E PG++ + G LA GY+ D H+ THP
Sbjct: 2956 IPYGTPMTNQQMHVLNAALEPCPEWVPGQLYIGGSGLAEGYLN--DRHK-TQAAFITHPA 3012
Query: 204 FA-KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377
+LY+TGD + +G I + GR D QVKIRGHRV+L E+++A++ P + ++ +
Sbjct: 3013 TGERLYKTGDLARVRPEGFIEFLGREDQQVKIRGHRVELGEIENALTLHPQIKEALITLH 3072
Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
G S +LA++T+ + +A+ + L L +MIP + PV NGK+
Sbjct: 3073 GESISGKRLLAYLTVQQQP-PAAEELRDHLAQVLPRFMIPDHFFFLTEFPVTANGKI 3128
>UniRef50_Q9FB27 Cluster: Peptide synthetase NRPS9-8; n=2;
Actinomycetales|Rep: Peptide synthetase NRPS9-8 -
Streptomyces verticillus
Length = 2162
Score = 100 bits (239), Expect = 3e-20
Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGKDPHR-FIHNPHNTH 197
+PIG P++ +V+ D R V G GE+ + G +ARGY+ R +D F +P T
Sbjct: 1868 LPIGRPVAGTWVHPRDHRGRTVPLGVAGELSIGGAGVARGYLGRPRDTAAAFRPDPEATA 1927
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P + Y TGD G L G + + GRAD QVKIRG RV+L E++ + T P + +V+
Sbjct: 1928 PG-GRAYATGDLGRYLPDGNLEFLGRADHQVKIRGFRVELGEIEAVLDTHPELQRTIVMA 1986
Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545
G + ++A+V P R +I+ + L YM+P VI ++ VP+ GKV
Sbjct: 1987 RGDHPGDQVLVAYVLPAPGRRPEPADIQGYVRDRLPRYMVPTAVIVLDAVPLTAAGKV 2044
Score = 79.4 bits (187), Expect = 5e-14
Identities = 61/187 (32%), Positives = 97/187 (51%), Gaps = 13/187 (6%)
Frame = +3
Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197
VPIG PI+N V+LLD+ R V +G GE+ + G +A GY+ + RF+ P +
Sbjct: 796 VPIGRPIANTTVHLLDQRRRPVPDGVVGELWIGGAGVADGYLGRPELTGERFL--PSDYP 853
Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374
P+ ++YRTGD G + Y GR D+QVKIRG RV+ E + +++ P V VV+
Sbjct: 854 PDGGRVYRTGDLARRRADGTLEYLGRTDAQVKIRGVRVEPAETEAVLASHPGVGQAVVVA 913
Query: 375 YGVES---SNP---EILAFVTINPEARMSA---KNIEAELTSSLTDYMIPQV-IEIETVP 524
E S+P E+ + P A + + A L ++ +P V + ++ +P
Sbjct: 914 RLDEDPGRSSPLAGELTLTGYVVPARGAQAPPHEELIAYCRERLPEHFVPAVLVTLDALP 973
Query: 525 VLVNGKV 545
V +GK+
Sbjct: 974 VTGHGKI 980
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 599,378,977
Number of Sequences: 1657284
Number of extensions: 13030065
Number of successful extensions: 38362
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 34080
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36160
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 35405708495
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -