BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= I10A02NGRL0001_A14 (545 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q402E3 Cluster: Ebony; n=4; Neoptera|Rep: Ebony - Papil... 254 1e-66 UniRef50_Q9GSP4 Cluster: Mutant e4 ebony; n=2; Drosophila|Rep: M... 200 1e-50 UniRef50_O76858 Cluster: Ebony protein; n=18; Diptera|Rep: Ebony... 200 1e-50 UniRef50_UPI0000DB6BFA Cluster: PREDICTED: similar to ebony CG33... 168 6e-41 UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2; Cyanobacte... 124 1e-27 UniRef50_Q08787 Cluster: Surfactin synthetase subunit 3; n=9; Ba... 124 1e-27 UniRef50_Q0LPK1 Cluster: Amino acid adenylation; n=1; Herpetosip... 121 9e-27 UniRef50_A1KQR7 Cluster: RhiB protein; n=1; Burkholderia rhizoxi... 121 9e-27 UniRef50_Q8VQF9 Cluster: Peptide synthetase XpsA; n=1; Xenorhabd... 120 2e-26 UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular... 119 4e-26 UniRef50_Q8VQF8 Cluster: Peptide synthetase XpsB; n=1; Xenorhabd... 119 4e-26 UniRef50_Q4C3C2 Cluster: Amino acid adenylation; n=1; Crocosphae... 119 4e-26 UniRef50_Q0B1F6 Cluster: Amino acid adenylation domain; n=2; Bac... 119 4e-26 UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibio... 118 7e-26 UniRef50_Q2N3S9 Cluster: Hybrid nonribosomal peptide synthetase/... 118 7e-26 UniRef50_Q84BC8 Cluster: NcpA; n=5; Cyanobacteria|Rep: NcpA - No... 118 9e-26 UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3; ... 117 2e-25 UniRef50_Q0LIS9 Cluster: Amino acid adenylation; n=1; Herpetosip... 117 2e-25 UniRef50_Q4KCD8 Cluster: Nonribosomal peptide synthase; n=2; cel... 116 3e-25 UniRef50_Q1DBW4 Cluster: Non-ribosomal peptide synthetase; n=3; ... 116 3e-25 UniRef50_O68006 Cluster: Bacitracin synthetase 1 (BA1) [Includes... 116 3e-25 UniRef50_Q2VQ15 Cluster: Nonribosomal peptide synthetase C; n=3;... 116 4e-25 UniRef50_Q4ZT67 Cluster: Amino acid adenylation; n=15; Bacteria|... 116 5e-25 UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 116 5e-25 UniRef50_UPI000038CB2F Cluster: COG1020: Non-ribosomal peptide s... 115 6e-25 UniRef50_Q93H59 Cluster: Non-ribosimal peptide synthetase; n=1; ... 115 6e-25 UniRef50_Q7N7D0 Cluster: Complete genome; segment 5/17; n=1; Pho... 115 6e-25 UniRef50_Q3M5N4 Cluster: Amino acid adenylation; n=1; Anabaena v... 115 6e-25 UniRef50_Q93N89 Cluster: Peptide synthetase; n=1; Streptomyces l... 115 6e-25 UniRef50_Q4C3C3 Cluster: Non-ribosomal peptide synthase:Amino ac... 115 6e-25 UniRef50_Q1D6A0 Cluster: Non-ribosomal peptide synthetase; n=7; ... 115 6e-25 UniRef50_Q0SKF6 Cluster: Non-ribosomal peptide synthetase; n=2; ... 115 6e-25 UniRef50_A7BXM0 Cluster: Non-ribosomal peptide synthetase; n=2; ... 115 6e-25 UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine syn... 115 6e-25 UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C ... 115 6e-25 UniRef50_Q83DF1 Cluster: Peptide synthetase, putative; n=6; Coxi... 115 8e-25 UniRef50_Q70C47 Cluster: Polyketide non-ribosomal peptide syntha... 115 8e-25 UniRef50_Q2VQ13 Cluster: Nonribosomal peptide synthetase E; n=1;... 115 8e-25 UniRef50_Q8L334 Cluster: Peptide synthetase; n=14; Nostocaceae|R... 114 1e-24 UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2; Bac... 114 1e-24 UniRef50_A5N8Z4 Cluster: Predicted hybrid nonribosomal peptide s... 114 1e-24 UniRef50_A3YFF7 Cluster: Amino acid adenylation; n=1; Marinomona... 114 1e-24 UniRef50_A3INW9 Cluster: Amino acid adenylation; n=1; Cyanothece... 114 1e-24 UniRef50_A7T272 Cluster: Predicted protein; n=1; Nematostella ve... 114 1e-24 UniRef50_A0UUS4 Cluster: Amino acid adenylation domain; n=1; Clo... 114 1e-24 UniRef50_O31782 Cluster: Polyketide synthase of type I; n=2; Bac... 113 2e-24 UniRef50_A5FI48 Cluster: Amino acid adenylation domain; n=2; cel... 113 2e-24 UniRef50_A3INW8 Cluster: Peptide synthetase; n=3; Chroococcales|... 113 2e-24 UniRef50_Q4KES9 Cluster: Nonribosomal peptide synthetase; n=6; B... 113 3e-24 UniRef50_Q4ZT69 Cluster: Amino acid adenylation; n=8; cellular o... 113 3e-24 UniRef50_A7IZW1 Cluster: OciA; n=1; Planktothrix agardhii NIVA-C... 113 3e-24 UniRef50_A0ZF79 Cluster: Non-ribosomal peptide synthase; n=6; Cy... 113 3e-24 UniRef50_Q0AY10 Cluster: Non-ribosomal peptide synthetase module... 112 4e-24 UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC 71... 112 6e-24 UniRef50_Q333V5 Cluster: NRPS protein; n=2; Actinomycetales|Rep:... 112 6e-24 UniRef50_Q18BS4 Cluster: Putative nonribosomal peptide synthetas... 112 6e-24 UniRef50_Q0RI59 Cluster: Non-ribosomal peptide synthetase; n=3; ... 112 6e-24 UniRef50_Q08MM0 Cluster: Linear gramicidin synthetase subunit B;... 112 6e-24 UniRef50_A0UVH5 Cluster: Amino acid adenylation domain; n=2; Bac... 112 6e-24 UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep... 112 6e-24 UniRef50_Q3M5M7 Cluster: Amino acid adenylation; n=1; Anabaena v... 111 8e-24 UniRef50_O07944 Cluster: Pristinamycin I synthase 3 and 4; n=2; ... 111 8e-24 UniRef50_A6ASZ6 Cluster: Enterobactin synthetase component F; n=... 111 8e-24 UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1;... 111 1e-23 UniRef50_A3KFG5 Cluster: PstC protein; n=2; Actinomycetales|Rep:... 111 1e-23 UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1; Alca... 111 1e-23 UniRef50_UPI000038DECD Cluster: COG1020: Non-ribosomal peptide s... 110 2e-23 UniRef50_Q93N87 Cluster: Peptide synthetase; n=12; Bacteria|Rep:... 110 2e-23 UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide synthetase/polyke... 110 2e-23 UniRef50_A4PHL4 Cluster: Non ribosomal peptide synthetase for vi... 110 2e-23 UniRef50_Q8PKR8 Cluster: ATP-dependent serine activating enzyme;... 110 2e-23 UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3; ... 110 2e-23 UniRef50_Q5Z1T0 Cluster: Putative non-ribosomal peptide syntheta... 110 2e-23 UniRef50_Q2ANW8 Cluster: Non-ribosomal peptide synthase:Amino ac... 110 2e-23 UniRef50_UPI000038CDA7 Cluster: COG1020: Non-ribosomal peptide s... 109 3e-23 UniRef50_Q5YPH7 Cluster: Putative non-ribosomal peptide syntheta... 109 3e-23 UniRef50_Q3M3K1 Cluster: Amino acid adenylation precursor; n=2; ... 109 3e-23 UniRef50_Q1RS73 Cluster: NRPS/PKS protein; n=5; Bacteria|Rep: NR... 109 3e-23 UniRef50_Q0LLT6 Cluster: Amino acid adenylation; n=1; Herpetosip... 109 3e-23 UniRef50_A3DGP7 Cluster: Amino acid adenylation domain; n=1; Clo... 109 3e-23 UniRef50_Q3M1N0 Cluster: Amino acid adenylation; n=2; Bacteria|R... 109 4e-23 UniRef50_Q2SKF9 Cluster: Non-ribosomal peptide synthetase module... 109 4e-23 UniRef50_Q04747 Cluster: Surfactin synthetase subunit 2; n=9; Ba... 109 4e-23 UniRef50_O68008 Cluster: Bacitracin synthetase 3 (BA3) [Includes... 109 4e-23 UniRef50_Q84DH9 Cluster: Peptide synthase; n=3; Streptomyces|Rep... 109 5e-23 UniRef50_Q1RS70 Cluster: Hybrid NRPS/PKS; n=4; cellular organism... 109 5e-23 UniRef50_A0ZL90 Cluster: Non-ribosomal peptide synthase; n=1; No... 109 5e-23 UniRef50_Q8GN23 Cluster: Peptide synthetase; n=1; Fischerella sp... 108 7e-23 UniRef50_Q84BC7 Cluster: NcpB; n=3; Cyanobacteria|Rep: NcpB - No... 108 7e-23 UniRef50_Q333U8 Cluster: NRPS protein; n=1; Micromonospora sp. M... 108 7e-23 UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosip... 108 7e-23 UniRef50_A3IZW4 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 108 7e-23 UniRef50_A0PTU8 Cluster: Non-ribosomal peptide synthetase MbtE; ... 108 7e-23 UniRef50_O30409 Cluster: Tyrocidine synthetase 3 (Tyrocidine syn... 108 7e-23 UniRef50_Q93H68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 108 9e-23 UniRef50_Q87WM7 Cluster: Non-ribosomal peptide synthetase, termi... 108 9e-23 UniRef50_Q5ZTI3 Cluster: Peptide synthetase, non-ribosomal; n=2;... 108 9e-23 UniRef50_A6E8C1 Cluster: Amino acid adenylation; n=1; Pedobacter... 108 9e-23 UniRef50_A3WXS1 Cluster: Probable non-ribosomal peptide syntheta... 108 9e-23 UniRef50_A0ZF81 Cluster: Amino acid adenylation protein; n=3; Ba... 108 9e-23 UniRef50_P27206 Cluster: Surfactin synthetase subunit 1; n=15; B... 108 9e-23 UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomona... 107 1e-22 UniRef50_Q1D3K4 Cluster: Non-ribosomal peptide synthase; n=2; My... 107 1e-22 UniRef50_Q0RMQ5 Cluster: Putative non-ribosomal peptide syntheta... 107 1e-22 UniRef50_A5IDB4 Cluster: Peptide synthetase; n=4; Legionella pne... 107 1e-22 UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5; roo... 107 1e-22 UniRef50_Q5JCL8 Cluster: Putative non-ribosomal peptide syntheta... 107 2e-22 UniRef50_Q1D3K7 Cluster: Non-ribosomal peptide synthase; n=1; My... 107 2e-22 UniRef50_Q08XI8 Cluster: Beta-lactamase, putative; n=3; Bacteria... 107 2e-22 UniRef50_A4PHM3 Cluster: Hybrid non ribosomal peptide synthetase... 107 2e-22 UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1; Clo... 107 2e-22 UniRef50_Q881Q3 Cluster: Non-ribosomal peptide synthetase, termi... 107 2e-22 UniRef50_Q2Y7Z5 Cluster: Amino acid adenylation; n=2; Nitrosospi... 107 2e-22 UniRef50_Q50857 Cluster: Saframycin Mx1 synthetase B; n=1; Myxoc... 107 2e-22 UniRef50_A4C379 Cluster: Non-ribosomal peptide synthetase, termi... 107 2e-22 UniRef50_P45745 Cluster: Dimodular nonribosomal peptide syntheta... 107 2e-22 UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces... 106 3e-22 UniRef50_Q0S1Z9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 106 3e-22 UniRef50_A5FI40 Cluster: Amino acid adenylation domain; n=1; Fla... 106 3e-22 UniRef50_A3DGP4 Cluster: Amino acid adenylation domain; n=1; Clo... 106 3e-22 UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular orga... 106 4e-22 UniRef50_Q4C9F4 Cluster: Non-ribosomal peptide synthase:Amino ac... 106 4e-22 UniRef50_Q1D3L3 Cluster: Non-ribosomal peptide synthase; n=1; My... 106 4e-22 UniRef50_Q0PH94 Cluster: MassC; n=1; Pseudomonas fluorescens|Rep... 106 4e-22 UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin s... 106 4e-22 UniRef50_A3I9A7 Cluster: Peptide synthetase; n=1; Bacillus sp. B... 106 4e-22 UniRef50_Q83Z53 Cluster: Putisolvin synthetase; n=3; Bacteria|Re... 105 5e-22 UniRef50_Q70P97 Cluster: MelC protein; n=4; Cystobacteraceae|Rep... 105 5e-22 UniRef50_A4JPB0 Cluster: Amino acid adenylation domain; n=1; Bur... 105 5e-22 UniRef50_A4FE18 Cluster: Non-ribosomal peptide synthetase; n=3; ... 105 5e-22 UniRef50_A4BRH4 Cluster: Probable peptide synthetase protein; n=... 105 5e-22 UniRef50_A1ZSC1 Cluster: Mixed type I polyketide synthase-peptid... 105 5e-22 UniRef50_A1G2S8 Cluster: Amino acid adenylation domain; n=1; Sal... 105 5e-22 UniRef50_P40806 Cluster: Putative polyketide synthase pksJ; n=9;... 105 5e-22 UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1; ... 105 7e-22 UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Re... 105 7e-22 UniRef50_Q70C52 Cluster: Non-ribosomal peptide synthase; n=1; Xa... 105 7e-22 UniRef50_Q6YK39 Cluster: Bacillomycin D synthetase C; n=4; Bacil... 105 7e-22 UniRef50_Q4U445 Cluster: DszC; n=3; Proteobacteria|Rep: DszC - P... 105 7e-22 UniRef50_Q44103 Cluster: Peptide-synthetase; n=1; Amycolatopsis ... 105 7e-22 UniRef50_A7BRU4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 105 7e-22 UniRef50_A4CG27 Cluster: Amino acid adenylation; n=2; Pseudoalte... 105 7e-22 UniRef50_A0YGI5 Cluster: Peptide synthetase; n=1; marine gamma p... 105 7e-22 UniRef50_A0UVJ0 Cluster: Amino acid adenylation domain; n=2; Clo... 105 7e-22 UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide syntheta... 105 9e-22 UniRef50_Q89T13 Cluster: Bll2237 protein; n=2; Bradyrhizobium|Re... 105 9e-22 UniRef50_Q4ZV19 Cluster: Non-ribosomal peptide synthase:Amino ac... 105 9e-22 UniRef50_Q2JA66 Cluster: Amino acid adenylation; n=15; Bacteria|... 105 9e-22 UniRef50_Q2JA64 Cluster: Amino acid adenylation; n=3; Actinomyce... 105 9e-22 UniRef50_Q0SEB1 Cluster: Non-ribosomal peptide synthetase; n=2; ... 105 9e-22 UniRef50_Q9RFK5 Cluster: MtaG; n=4; Cystobacteraceae|Rep: MtaG -... 105 9e-22 UniRef50_Q847C8 Cluster: NdaB; n=32; Cyanobacteria|Rep: NdaB - N... 105 9e-22 UniRef50_Q4CA71 Cluster: Amino acid adenylation; n=1; Crocosphae... 105 9e-22 UniRef50_Q211M6 Cluster: Amino acid adenylation; n=1; Rhodopseud... 105 9e-22 UniRef50_Q0B1F5 Cluster: Amino acid adenylation domain; n=1; Bur... 105 9e-22 UniRef50_Q08MR4 Cluster: Linear gramicidin synthetase subunit D;... 105 9e-22 UniRef50_A6LQ10 Cluster: Amino acid adenylation domain; n=1; Clo... 105 9e-22 UniRef50_A1G7W6 Cluster: Amino acid adenylation domain; n=2; Sal... 105 9e-22 UniRef50_UPI000045C11E Cluster: COG1020: Non-ribosomal peptide s... 104 1e-21 UniRef50_Q2SHZ4 Cluster: Non-ribosomal peptide synthetase module... 104 1e-21 UniRef50_Q0PH95 Cluster: MassB; n=2; Pseudomonas fluorescens|Rep... 104 1e-21 UniRef50_Q0LP44 Cluster: Amino acid adenylation; n=1; Herpetosip... 104 1e-21 UniRef50_A6YEH8 Cluster: CmnG; n=1; Saccharothrix mutabilis subs... 104 1e-21 UniRef50_A4FCX9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 104 1e-21 UniRef50_A3IP47 Cluster: Peptide synthetase; n=2; Cyanobacteria|... 104 1e-21 UniRef50_UPI000045BE69 Cluster: COG1020: Non-ribosomal peptide s... 104 2e-21 UniRef50_Q0SE34 Cluster: Non-ribosomal peptide synthetase; n=1; ... 104 2e-21 UniRef50_A4F3K7 Cluster: Non-ribosomal peptide synthetase; n=3; ... 104 2e-21 UniRef50_Q2SFM4 Cluster: Non-ribosomal peptide synthetase module... 103 2e-21 UniRef50_Q6E7J8 Cluster: JamL; n=4; Bacteria|Rep: JamL - Lyngbya... 103 2e-21 UniRef50_Q5MP00 Cluster: OnnI; n=1; symbiont bacterium of Theone... 103 2e-21 UniRef50_Q3WDU5 Cluster: Amino acid adenylation; n=1; Frankia sp... 103 2e-21 UniRef50_Q1D6B8 Cluster: Non-ribosomal peptide synthetase; n=5; ... 103 2e-21 UniRef50_Q1D3K9 Cluster: Non-ribosomal peptide synthase; n=1; My... 103 2e-21 UniRef50_O87314 Cluster: FxbC; n=5; Mycobacterium smegmatis|Rep:... 103 2e-21 UniRef50_A3HT12 Cluster: Non-ribosomal peptide synthase; n=1; Al... 103 2e-21 UniRef50_A0ZL89 Cluster: Non-ribosomal peptide synthase; n=1; No... 103 2e-21 UniRef50_Q8CJX2 Cluster: CDA peptide synthetase III; n=3; Strept... 103 3e-21 UniRef50_Q7N3S1 Cluster: Complete genome; segment 9/17; n=1; Pho... 103 3e-21 UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4; Ph... 103 3e-21 UniRef50_Q20CI8 Cluster: CesB; n=7; cellular organisms|Rep: CesB... 103 3e-21 UniRef50_Q1IA18 Cluster: Putative non-ribosomal peptide syntheta... 103 3e-21 UniRef50_Q0K0K4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 103 3e-21 UniRef50_Q08N46 Cluster: Condensation domain protein; n=3; Stigm... 103 3e-21 UniRef50_A0NTU6 Cluster: Putative non-ribosomal peptide syntheta... 103 3e-21 UniRef50_UPI00005F995E Cluster: COG1020: Non-ribosomal peptide s... 103 4e-21 UniRef50_Q9F9L4 Cluster: Micrococcin P1 peptide synthetase; n=1;... 103 4e-21 UniRef50_Q70AZ6 Cluster: Non-ribosomal peptide synthetase; n=6; ... 103 4e-21 UniRef50_Q0S7I5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 103 4e-21 UniRef50_A7IZW2 Cluster: OciB; n=1; Planktothrix agardhii NIVA-C... 103 4e-21 UniRef50_A4KVL5 Cluster: Non-ribosomal peptide synthetase module... 103 4e-21 UniRef50_A3KFG6 Cluster: PstD protein; n=1; Actinoplanes friulie... 103 4e-21 UniRef50_A0ZF82 Cluster: Non-ribosomal peptide synthase; n=2; No... 103 4e-21 UniRef50_Q8YTR5 Cluster: Peptide synthetase; n=7; Cyanobacteria|... 102 5e-21 UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7; Pseudomona... 102 5e-21 UniRef50_Q9K5M1 Cluster: Peptide synthetase; n=8; Bacteria|Rep: ... 102 5e-21 UniRef50_Q6HXY8 Cluster: AMP-binding enzyme; n=10; Bacillus cere... 102 5e-21 UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces... 102 5e-21 UniRef50_Q0YRD8 Cluster: Amino acid adenylation; n=2; cellular o... 102 5e-21 UniRef50_A0V6U0 Cluster: Amino acid adenylation domain; n=1; Del... 102 5e-21 UniRef50_Q2SW14 Cluster: Peptide synthetase, putative; n=1; Burk... 102 6e-21 UniRef50_Q7BQ70 Cluster: Putative peptide synthetase/polyketide ... 102 6e-21 UniRef50_Q70JX4 Cluster: FenD protein; n=18; Bacillus|Rep: FenD ... 102 6e-21 UniRef50_Q0YRE2 Cluster: Amino acid adenylation; n=1; Chlorobium... 102 6e-21 UniRef50_Q0LKI8 Cluster: Amino acid adenylation; n=1; Herpetosip... 102 6e-21 UniRef50_A3IZB3 Cluster: Amino acid adenylation; n=2; Chroococca... 102 6e-21 UniRef50_A0UXC9 Cluster: Amino acid adenylation domain; n=2; Bac... 102 6e-21 UniRef50_A0JZK7 Cluster: Amino acid adenylation domain; n=1; Art... 102 6e-21 UniRef50_Q8YTR8 Cluster: Peptide synthetase; n=2; Nostocaceae|Re... 101 8e-21 UniRef50_Q8CQA8 Cluster: Surfactin synthetase; n=14; Staphylococ... 101 8e-21 UniRef50_Q63CQ6 Cluster: Multifunctional nonribosomal peptide sy... 101 8e-21 UniRef50_Q63CQ5 Cluster: Multifunctional nonribosomal peptide sy... 101 8e-21 UniRef50_Q9Z5F4 Cluster: Ta1; n=4; Bacteria|Rep: Ta1 - Myxococcu... 101 8e-21 UniRef50_Q2ANX0 Cluster: Non-ribosomal peptide synthase:Amino ac... 101 8e-21 UniRef50_Q1D8L0 Cluster: Non-ribosomal peptide synthetase; n=1; ... 101 8e-21 UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1; My... 101 8e-21 UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8; Ba... 101 8e-21 UniRef50_Q0VZ70 Cluster: Non ribosomal peptide synthase; n=1; Ch... 101 8e-21 UniRef50_A7BKL9 Cluster: Non-ribosomal peptide synthetase; n=2; ... 101 8e-21 UniRef50_A5W120 Cluster: Amino acid adenylation domain; n=3; Bac... 101 8e-21 UniRef50_A5EHY7 Cluster: Non ribosomal peptide synthase; n=1; Br... 101 8e-21 UniRef50_A3YGI9 Cluster: Amino acid adenylation; n=1; Marinomona... 101 8e-21 UniRef50_Q88JT4 Cluster: Antibiotic biosynthesis protein, putati... 101 1e-20 UniRef50_Q6VT95 Cluster: Mixed type I polyketide synthase/nonrib... 101 1e-20 UniRef50_Q1D3T0 Cluster: Non-ribosomal peptide synthase MxaA; n=... 101 1e-20 UniRef50_Q0SKF9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 101 1e-20 UniRef50_A6P624 Cluster: Nonribosomal peptide synthetase; n=1; M... 101 1e-20 UniRef50_A4FEM4 Cluster: Non-ribosomal peptide synthetase module... 101 1e-20 UniRef50_A0UXD5 Cluster: Amino acid adenylation domain; n=1; Clo... 101 1e-20 UniRef50_UPI00015978D8 Cluster: NrsC; n=1; Bacillus amyloliquefa... 101 1e-20 UniRef50_Q3M3K2 Cluster: Amino acid adenylation; n=2; Nostocacea... 101 1e-20 UniRef50_Q6WZB2 Cluster: Nonribosomal peptide synthetase; n=1; S... 101 1e-20 UniRef50_Q5J1Q7 Cluster: NocA; n=1; Nocardia uniformis subsp. ts... 101 1e-20 UniRef50_Q1IBI9 Cluster: Putative non-ribosomal peptide syntheta... 101 1e-20 UniRef50_Q1DCS5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 101 1e-20 UniRef50_Q1D593 Cluster: Non-ribosomal peptide synthetase; n=4; ... 101 1e-20 UniRef50_Q0S6F2 Cluster: Non-ribosomal peptide synthetase; n=2; ... 101 1e-20 UniRef50_A5FI38 Cluster: Amino acid adenylation domain; n=2; Bac... 101 1e-20 UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide syntheta... 101 1e-20 UniRef50_A0V6U3 Cluster: Amino acid adenylation domain; n=1; Del... 101 1e-20 UniRef50_Q5YPH6 Cluster: Putative non-ribosomal peptide syntheta... 100 2e-20 UniRef50_Q47NR9 Cluster: Non-ribosomal peptide synthase:Amino ac... 100 2e-20 UniRef50_Q5IW58 Cluster: Phosphinothricin tripeptide synthetase ... 100 2e-20 UniRef50_Q5DIV7 Cluster: PvdI; n=5; Pseudomonas aeruginosa|Rep: ... 100 2e-20 UniRef50_Q4H1C8 Cluster: Non-ribosomal peptide synthetase B; n=1... 100 2e-20 UniRef50_A5YBV1 Cluster: Fusaricidin synthetase; n=1; Paenibacil... 100 2e-20 UniRef50_Q8YTR9 Cluster: Peptide synthetase; n=2; Nostocaceae|Re... 100 3e-20 UniRef50_Q4ZVI3 Cluster: Amino acid adenylation; n=3; Pseudomona... 100 3e-20 UniRef50_Q311J0 Cluster: Amino acid adenylation; n=2; Bacteria|R... 100 3e-20 UniRef50_Q9FB27 Cluster: Peptide synthetase NRPS9-8; n=2; Actino... 100 3e-20 UniRef50_Q5DIP4 Cluster: PvdJ; n=19; root|Rep: PvdJ - Pseudomona... 100 3e-20 UniRef50_Q216S9 Cluster: Amino acid adenylation; n=1; Rhodopseud... 100 3e-20 UniRef50_Q0LLQ8 Cluster: Amino acid adenylation; n=2; Herpetosip... 100 3e-20 UniRef50_Q094I7 Cluster: Aminotransferase, class III family; n=9... 100 3e-20 UniRef50_A6VYF8 Cluster: Amino acid adenylation domain; n=1; Mar... 100 3e-20 UniRef50_A0UVH3 Cluster: Amino acid adenylation domain; n=1; Clo... 100 3e-20 UniRef50_Q2UIN6 Cluster: Non-ribosomal peptide synthetase module... 100 3e-20 UniRef50_UPI00005F935B Cluster: COG1020: Non-ribosomal peptide s... 99 3e-20 UniRef50_Q87WM8 Cluster: Non-ribosomal peptide synthetase, initi... 99 3e-20 UniRef50_Q3JS97 Cluster: Unnamed protein product; n=10; Burkhold... 99 3e-20 UniRef50_O31827 Cluster: Plipastatin synthetase; n=7; Bacillus|R... 99 3e-20 UniRef50_Q643C7 Cluster: Mannopeptimycin peptide synthetase MppA... 99 3e-20 UniRef50_Q4CA68 Cluster: Amino acid adenylation; n=1; Crocosphae... 99 3e-20 UniRef50_O69146 Cluster: Peptide synthetase; n=1; Bacillus subti... 99 3e-20 UniRef50_A5MZS0 Cluster: Predicted nonribosomal peptide syntheta... 99 3e-20 UniRef50_A1G504 Cluster: Amino acid adenylation domain; n=1; Sal... 99 3e-20 UniRef50_A1FGJ0 Cluster: Amino acid adenylation; n=2; cellular o... 99 3e-20 UniRef50_A0V6T7 Cluster: Amino acid adenylation domain; n=2; Com... 99 3e-20 UniRef50_Q9AKS6 Cluster: Siderophore non-ribosomal peptide synth... 100 4e-20 UniRef50_Q93N86 Cluster: Peptide synthetase; n=2; Actinomycetale... 100 4e-20 UniRef50_Q216S7 Cluster: Amino acid adenylation; n=1; Rhodopseud... 100 4e-20 UniRef50_Q1ER08 Cluster: Cereulide synthetase 1; n=6; Bacillus|R... 100 4e-20 UniRef50_Q0LN70 Cluster: Amino acid adenylation; n=1; Herpetosip... 100 4e-20 UniRef50_Q47NS1 Cluster: Amino acid adenylation; n=1; Thermobifi... 99 6e-20 UniRef50_Q3JQV3 Cluster: Nonribosomal peptide synthetase; n=24; ... 99 6e-20 UniRef50_Q5J1Q6 Cluster: NocB; n=1; Nocardia uniformis subsp. ts... 99 6e-20 UniRef50_Q0VZ71 Cluster: Non ribosomal peptide synthase; n=1; Ch... 99 6e-20 UniRef50_Q0MYM1 Cluster: Nonribosomal peptide synthetase; n=2; L... 99 6e-20 UniRef50_A2R200 Cluster: Contig An13c0090, complete genome; n=1;... 99 6e-20 UniRef50_O68007 Cluster: Bacitracin synthetase 2 (BA2) [Includes... 99 6e-20 UniRef50_Q8YTS0 Cluster: Microcystin synthetase B; n=3; Nostocac... 99 8e-20 UniRef50_Q6N4J8 Cluster: Possible McyE polykeitde synthase and p... 99 8e-20 UniRef50_Q8KSQ1 Cluster: Peptide synthetase ScpsA; n=1; Saccharo... 99 8e-20 UniRef50_Q0S3K6 Cluster: Non-ribosomal peptide synthetase; n=2; ... 99 8e-20 UniRef50_A7BWG0 Cluster: Non-ribosomal peptide synthetase; n=2; ... 99 8e-20 UniRef50_A4XD37 Cluster: Amino acid adenylation domain; n=2; Sal... 99 8e-20 UniRef50_A4D936 Cluster: CrpD; n=2; Nostocaceae|Rep: CrpD - Nost... 99 8e-20 UniRef50_A3X327 Cluster: Non-ribosomal siderophore peptide synth... 99 8e-20 UniRef50_Q8YTR4 Cluster: All2649 protein; n=3; Nostocaceae|Rep: ... 98 1e-19 UniRef50_Q7N7D7 Cluster: Similarities with probable non-ribosoma... 98 1e-19 UniRef50_Q2T5X0 Cluster: Peptide synthetase, putative; n=11; pse... 98 1e-19 UniRef50_Q9FB18 Cluster: Peptide synthetase NRPS2-1; n=1; Strept... 98 1e-19 UniRef50_Q8G982 Cluster: Peptide synthetase; n=102; Cyanobacteri... 98 1e-19 UniRef50_Q3WHQ1 Cluster: Non-ribosomal peptide synthase:Amino ac... 98 1e-19 UniRef50_Q0LN68 Cluster: Amino acid adenylation; n=1; Herpetosip... 98 1e-19 UniRef50_A4C382 Cluster: Amino acid adenylation; n=1; Pseudoalte... 98 1e-19 UniRef50_A1FGJ5 Cluster: Amino acid adenylation; n=1; Pseudomona... 98 1e-19 UniRef50_A0Z9R9 Cluster: Putative uncharacterized protein; n=1; ... 98 1e-19 UniRef50_Q5DIU0 Cluster: PvdI; n=3; cellular organisms|Rep: PvdI... 98 1e-19 UniRef50_Q0RMQ8 Cluster: Non-ribosomal peptide synthetase; n=1; ... 98 1e-19 UniRef50_A6V024 Cluster: Amino acid adenylation domain; n=1; Pse... 98 1e-19 UniRef50_Q12HS0 Cluster: Amino acid adenylation; n=1; Shewanella... 97 2e-19 UniRef50_A7IJ33 Cluster: Amino acid adenylation domain; n=1; Xan... 97 2e-19 UniRef50_Q62C03 Cluster: Nonribosomal peptide synthetase DhbF; n... 97 2e-19 UniRef50_Q0LP26 Cluster: Amino acid adenylation; n=1; Herpetosip... 97 2e-19 UniRef50_O52803 Cluster: PCZA361.18; n=3; cellular organisms|Rep... 97 2e-19 UniRef50_A6VYG2 Cluster: Amino acid adenylation domain; n=1; Mar... 97 2e-19 UniRef50_A6EWZ1 Cluster: Peptide synthetase; n=1; Marinobacter a... 97 2e-19 UniRef50_A6E8C2 Cluster: Non-ribosomal peptide synthetase/polyke... 97 2e-19 UniRef50_A4ZPY5 Cluster: DepE; n=2; cellular organisms|Rep: DepE... 97 2e-19 UniRef50_A1EX06 Cluster: Bacitracin synthetase 3; n=1; Coxiella ... 97 2e-19 UniRef50_A0PRJ7 Cluster: Peptide synthetase Nrp; n=1; Mycobacter... 97 2e-19 UniRef50_Q09164 Cluster: Cyclosporine synthetase; n=8; Fungi/Met... 97 2e-19 UniRef50_A1D6D2 Cluster: Nonribosomal peptide synthase GliP2; n=... 97 2e-19 UniRef50_Q68RS4 Cluster: PrnA; n=1; Prochloron didemni|Rep: PrnA... 97 3e-19 UniRef50_Q06YZ2 Cluster: Nonribosomal peptide synthetase; n=1; S... 97 3e-19 UniRef50_A5EJ32 Cluster: Putative non-ribosomal peptide synthase... 97 3e-19 UniRef50_A4ZPY4 Cluster: DepD; n=3; Chromobacterium violaceum|Re... 97 3e-19 UniRef50_A4C380 Cluster: Putative uncharacterized protein; n=1; ... 97 3e-19 UniRef50_A0FCL0 Cluster: MerP; n=2; Streptomyces|Rep: MerP - Str... 97 3e-19 UniRef50_Q2T5Y9 Cluster: Peptide synthetase, putative; n=10; pse... 96 4e-19 UniRef50_Q939Z1 Cluster: Peptide synthetase; n=7; Actinomycetale... 96 4e-19 UniRef50_Q2XNF8 Cluster: Nonribosomal peptide synthetase-polyket... 96 4e-19 UniRef50_Q09E86 Cluster: AMP-binding enzyme domain protein; n=1;... 96 4e-19 UniRef50_A7DBD7 Cluster: Non-ribosomal peptide synthetase; n=4; ... 96 4e-19 UniRef50_A5FI53 Cluster: Amino acid adenylation domain; n=2; Bac... 96 4e-19 UniRef50_A4KVL6 Cluster: Non-ribosomal peptide synthetase module... 96 4e-19 UniRef50_A1ZVW4 Cluster: Linear gramicidin synthetase subunit B;... 96 4e-19 UniRef50_A1EX07 Cluster: Linear gramicidin synthetase subunit C;... 96 4e-19 UniRef50_A1EWJ3 Cluster: Peptide syntetase, degenerate; n=3; Cox... 96 4e-19 UniRef50_A0QH53 Cluster: Linear gramicidin synthetase subunit D;... 96 4e-19 UniRef50_Q93H69 Cluster: Non-ribosomal peptide synthetase; n=1; ... 96 5e-19 UniRef50_Q8KLL4 Cluster: StaB; n=1; Streptomyces toyocaensis|Rep... 96 5e-19 UniRef50_Q840C8 Cluster: Catechol siderophore synthase DhbF-like... 96 5e-19 UniRef50_Q2AZG3 Cluster: Non-ribosomal peptide synthase:Amino ac... 96 5e-19 UniRef50_Q08QA2 Cluster: Linear gramicidin synthetase subunit B;... 96 5e-19 UniRef50_A5EHY6 Cluster: Non-ribosomal peptide synthase; n=2; ce... 96 5e-19 UniRef50_Q93GZ0 Cluster: Non-ribosomal peptide synthetase; n=1; ... 95 7e-19 UniRef50_Q8DTJ7 Cluster: Putative surfactin synthetase; n=1; Str... 95 7e-19 UniRef50_Q7NVV9 Cluster: Synthetase CbsF; n=3; cellular organism... 95 7e-19 UniRef50_Q7N5R5 Cluster: Similar to antibiotic synthetase; n=1; ... 95 7e-19 UniRef50_Q8GGP3 Cluster: Hybrid nonribosomal peptide synthetase ... 95 7e-19 UniRef50_Q7DAG9 Cluster: Peptide synthetase, putative; n=10; Myc... 95 7e-19 UniRef50_Q6E7J5 Cluster: JamO; n=1; Lyngbya majuscula|Rep: JamO ... 95 7e-19 UniRef50_Q45R85 Cluster: Peptide synthetase; n=2; Actinomycetale... 95 7e-19 UniRef50_Q2VQ17 Cluster: Nonribosomal peptide synthetase A; n=1;... 95 7e-19 UniRef50_Q0VNL6 Cluster: Non-ribosomal peptide synthase; n=1; Al... 95 7e-19 UniRef50_A5XI24 Cluster: Non-ribosomal peptide synthase; n=23; B... 95 7e-19 UniRef50_A5P2I4 Cluster: Amino acid adenylation domain; n=6; Alp... 95 7e-19 UniRef50_A4Z4I9 Cluster: McnE; n=5; Cyanobacteria|Rep: McnE - Mi... 95 7e-19 UniRef50_A3N9X4 Cluster: Non-ribosomal peptide synthetase module... 95 7e-19 UniRef50_Q9LAS7 Cluster: Putative uncharacterized protein; n=1; ... 95 9e-19 UniRef50_Q3EYR3 Cluster: Peptide synthetase; n=3; Bacillus cereu... 95 9e-19 UniRef50_A3YGJ0 Cluster: Amino acid adenylation; n=1; Marinomona... 95 9e-19 UniRef50_A3JMY8 Cluster: Non-ribosomal peptide synthetase; n=4; ... 95 9e-19 UniRef50_A2C8M5 Cluster: Putative uncharacterized protein; n=1; ... 95 9e-19 UniRef50_A1TTJ0 Cluster: Amino acid adenylation domain; n=1; Aci... 95 9e-19 UniRef50_A1B557 Cluster: Amino acid adenylation domain; n=2; Pro... 95 9e-19 UniRef50_A5ABE0 Cluster: Contig An11c0010, complete genome; n=1;... 95 9e-19 UniRef50_Q2SGN2 Cluster: Non-ribosomal peptide synthetase module... 95 1e-18 UniRef50_Q6SK65 Cluster: Peptide synthetase; n=5; cellular organ... 95 1e-18 UniRef50_Q5V8A8 Cluster: LtxA; n=1; Lyngbya majuscula|Rep: LtxA ... 95 1e-18 UniRef50_Q3EYD4 Cluster: Peptide synthetase; n=2; Bacillus thuri... 95 1e-18 UniRef50_Q110E8 Cluster: Amino acid adenylation domain; n=1; Tri... 95 1e-18 UniRef50_Q0YRE6 Cluster: Amino acid adenylation; n=1; Chlorobium... 95 1e-18 UniRef50_Q0YRE1 Cluster: Amino acid adenylation; n=1; Chlorobium... 95 1e-18 UniRef50_Q02HM1 Cluster: Putative non-ribosomal peptide syntheta... 95 1e-18 UniRef50_A4X8P7 Cluster: Amino acid adenylation domain; n=1; Sal... 95 1e-18 UniRef50_A1BDX6 Cluster: Amino acid adenylation domain; n=1; Chl... 95 1e-18 UniRef50_A0ZF80 Cluster: Peptide synthetase; n=3; Nostocaceae|Re... 95 1e-18 UniRef50_Q9AMR5 Cluster: ID930; n=1; Bradyrhizobium japonicum|Re... 94 2e-18 UniRef50_Q7D791 Cluster: Peptide synthetase; n=18; Mycobacterium... 94 2e-18 UniRef50_Q50JA3 Cluster: Nonribosomal peptide synthetase; n=2; C... 94 2e-18 UniRef50_Q0K0K6 Cluster: Non-ribosomal peptide synthetase module... 94 2e-18 UniRef50_Q09D72 Cluster: Linear gramicidin synthetase subunit D;... 94 2e-18 UniRef50_P94873 Cluster: Alpha-aminoadipyl-cysteinyl-valine synt... 94 2e-18 UniRef50_A4XWA8 Cluster: Amino acid adenylation domain; n=1; Pse... 94 2e-18 UniRef50_A3YGJ1 Cluster: Amino acid adenylation; n=1; Marinomona... 94 2e-18 UniRef50_A3KI35 Cluster: Putative peptide synthetase; n=1; Strep... 94 2e-18 UniRef50_Q9RK14 Cluster: Putative peptide synthetase; n=1; Strep... 94 2e-18 UniRef50_Q9HYR8 Cluster: Probable non-ribosomal peptide syntheta... 94 2e-18 UniRef50_Q5YVZ9 Cluster: Putative non-ribosomal peptide syntheta... 94 2e-18 UniRef50_Q2T5W7 Cluster: Nonribosomal peptide synthetase, putati... 94 2e-18 UniRef50_Q9L8H4 Cluster: Actinomycin synthetase III; n=1; Strept... 94 2e-18 UniRef50_Q643C6 Cluster: Mannopeptimycin peptide synthetase MppB... 94 2e-18 UniRef50_Q0S5D8 Cluster: Non-ribosomal peptide synthetase; n=2; ... 94 2e-18 UniRef50_Q0P7K0 Cluster: Putative non-ribosomal peptide synthase... 94 2e-18 UniRef50_O68487 Cluster: Actinomycin synthetase II; n=1; Strepto... 94 2e-18 UniRef50_A7IJ32 Cluster: Amino acid adenylation domain; n=1; Xan... 94 2e-18 UniRef50_Q98JF4 Cluster: Peptide synthetase; n=1; Mesorhizobium ... 93 3e-18 UniRef50_Q93H04 Cluster: Non-ribosomal peptide synthetase; n=1; ... 93 3e-18 UniRef50_Q8YWG6 Cluster: Peptide synthetase; n=3; Nostocaceae|Re... 93 3e-18 UniRef50_Q2JYI9 Cluster: Vicibactin biosynthesis non-ribosomal p... 93 3e-18 UniRef50_Q9F5J4 Cluster: SimH; n=5; Streptomyces|Rep: SimH - Str... 93 3e-18 UniRef50_Q7CT27 Cluster: AGR_L_2309p; n=2; Agrobacterium tumefac... 93 3e-18 UniRef50_Q45R83 Cluster: Peptide synthetase; n=3; Actinobacteria... 93 3e-18 UniRef50_Q2L5R6 Cluster: Putative peptide synthetase; n=1; Clost... 93 3e-18 UniRef50_Q1D591 Cluster: Nonribosomal peptide synthetase; n=1; M... 93 3e-18 UniRef50_Q183T6 Cluster: D-alanine--poly(Phosphoribitol) ligase ... 93 3e-18 UniRef50_Q0S5F4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 93 3e-18 UniRef50_A7BKG9 Cluster: Peptide synthetase; n=2; Beggiatoa|Rep:... 93 3e-18 UniRef50_A6UN01 Cluster: Amino acid adenylation domain; n=1; Sin... 93 3e-18 UniRef50_A6UN00 Cluster: Amino acid adenylation domain; n=1; Sin... 93 3e-18 UniRef50_Q8CUZ9 Cluster: Monomodular nonribosomal peptide synthe... 93 4e-18 UniRef50_Q4KAY8 Cluster: Pyochelin synthetase F; n=1; Pseudomona... 93 4e-18 UniRef50_Q2Y7Z2 Cluster: Amino acid adenylation; n=1; Nitrosospi... 93 4e-18 UniRef50_Q8GAQ3 Cluster: BarG; n=1; Lyngbya majuscula|Rep: BarG ... 93 4e-18 UniRef50_Q0S6F3 Cluster: Non-ribosomal peptide synthetase; n=2; ... 93 4e-18 UniRef50_A6GK66 Cluster: Non-ribosomal peptide synthetase; n=1; ... 93 4e-18 UniRef50_A4C385 Cluster: Amino acid adenylation; n=6; Pseudoalte... 93 4e-18 UniRef50_A4BRH6 Cluster: Amino acid adenylation; n=1; Nitrococcu... 93 4e-18 UniRef50_A1TTI9 Cluster: Amino acid adenylation domain; n=1; Aci... 93 4e-18 UniRef50_A1G2S7 Cluster: Amino acid adenylation domain; n=1; Sal... 93 4e-18 UniRef50_Q70LM7 Cluster: Linear gramicidin synthetase subunit A ... 93 4e-18 UniRef50_Q8U9P4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 93 5e-18 UniRef50_Q9R686 Cluster: Gramicidin S synthetase 2, GRSB; n=1; B... 93 5e-18 UniRef50_Q0LP45 Cluster: Amino acid adenylation; n=1; Herpetosip... 93 5e-18 UniRef50_Q0LKI6 Cluster: Amino acid adenylation; n=1; Herpetosip... 93 5e-18 UniRef50_A6VVR6 Cluster: Amino acid adenylation domain; n=1; Mar... 93 5e-18 UniRef50_A1FGJ4 Cluster: Amino acid adenylation; n=1; Pseudomona... 93 5e-18 UniRef50_A0QHN3 Cluster: Syringomycin synthetase; n=3; Mycobacte... 93 5e-18 UniRef50_Q8U9Q1 Cluster: Peptide synthetase; n=1; Agrobacterium ... 92 7e-18 UniRef50_Q39GN5 Cluster: Non-ribosomal peptide synthase; n=16; B... 92 7e-18 UniRef50_Q2T5X7 Cluster: Peptide synthetase, putative; n=9; Burk... 92 7e-18 UniRef50_Q9FB33 Cluster: Peptide synthetase NRPS11-10; n=1; Stre... 92 7e-18 UniRef50_Q54298 Cluster: Pipecolate incorporating enzyme; n=4; c... 92 7e-18 UniRef50_Q21E99 Cluster: Amino acid adenylation; n=2; Bacteria|R... 92 7e-18 UniRef50_Q0SK68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 92 7e-18 UniRef50_A5A9U3 Cluster: Mps2 protein; n=2; Mycobacterium|Rep: M... 92 7e-18 UniRef50_A0UWE6 Cluster: Amino acid adenylation domain; n=1; Clo... 92 7e-18 UniRef50_A0PTU7 Cluster: Non-ribosomal peptide synthetase MbtF; ... 92 7e-18 UniRef50_A0ACQ7 Cluster: Putative peptide synthetase; n=1; Strep... 92 7e-18 UniRef50_P29698 Cluster: Enterobactin synthetase component F; n=... 92 7e-18 UniRef50_Q63CQ7 Cluster: Multifunctional nonribosomal peptide sy... 92 9e-18 UniRef50_Q4JTA1 Cluster: Non-ribosomal peptide synthetase; n=1; ... 92 9e-18 UniRef50_Q9FB24 Cluster: Peptide synthetase NRPS6; n=8; cellular... 92 9e-18 UniRef50_Q1D592 Cluster: Non-ribosomal peptide synthase/polyketi... 92 9e-18 UniRef50_Q1D4E9 Cluster: Non-ribosomal peptide synthase/polyketi... 92 9e-18 UniRef50_Q197G2 Cluster: Nonribosomal peptide synthetase; n=2; S... 92 9e-18 UniRef50_Q0LP42 Cluster: Amino acid adenylation; n=1; Herpetosip... 92 9e-18 UniRef50_A6VYF6 Cluster: Amino acid adenylation domain; n=1; Mar... 92 9e-18 UniRef50_A5W126 Cluster: Amino acid adenylation domain; n=2; Pse... 92 9e-18 UniRef50_A0U0U6 Cluster: Amino acid adenylation domain; n=5; Bur... 92 9e-18 UniRef50_P39845 Cluster: Peptide synthetase 1; n=8; Bacillus|Rep... 92 9e-18 UniRef50_Q6VT93 Cluster: Mixed type I polyketide synthase-peptid... 91 1e-17 UniRef50_Q1D3S3 Cluster: Non-ribosomal peptide synthase; n=3; Ba... 91 1e-17 UniRef50_A5FI45 Cluster: Amino acid adenylation domain; n=1; Fla... 91 1e-17 UniRef50_A4F9A4 Cluster: CDA peptide synthetase I; n=1; Saccharo... 91 1e-17 UniRef50_A3INW7 Cluster: Amino acid adenylation; n=1; Cyanothece... 91 1e-17 UniRef50_Q8GGR4 Cluster: Nonribosomal peptide synthetase; n=1; S... 91 2e-17 UniRef50_Q847C7 Cluster: NdaA; n=5; cellular organisms|Rep: NdaA... 91 2e-17 UniRef50_Q9FDB0 Cluster: Six-domain nonribosomal peptide synthet... 91 2e-17 UniRef50_Q2AZ45 Cluster: Amino acid adenylation; n=2; Bacillus c... 91 2e-17 UniRef50_Q0W980 Cluster: Non-ribosomal peptide synthetase; n=2; ... 91 2e-17 UniRef50_A1TG57 Cluster: Non-ribosomal peptide synthetase; n=3; ... 91 2e-17 UniRef50_A0ADQ3 Cluster: Putative non-ribosomal peptide syntheta... 91 2e-17 UniRef50_Q2SHZ1 Cluster: Non-ribosomal peptide synthetase module... 90 3e-17 UniRef50_Q5ZPA8 Cluster: TubD protein; n=4; cellular organisms|R... 90 3e-17 UniRef50_Q12IB9 Cluster: Amino acid adenylation; n=3; cellular o... 90 3e-17 UniRef50_Q0X0B9 Cluster: Putative non-ribosomal peptide syntheta... 90 3e-17 UniRef50_A4X8R2 Cluster: Amino acid adenylation domain; n=1; Sal... 90 3e-17 UniRef50_A4C386 Cluster: Amino acid adenylation; n=1; Pseudoalte... 90 3e-17 UniRef50_A1TTI8 Cluster: Amino acid adenylation domain; n=1; Aci... 90 3e-17 UniRef50_Q9I157 Cluster: PvdL; n=23; root|Rep: PvdL - Pseudomona... 90 4e-17 UniRef50_Q4ZV22 Cluster: Amino acid adenylation; n=3; Pseudomona... 90 4e-17 UniRef50_Q12Q14 Cluster: Amino acid adenylation; n=1; Shewanella... 90 4e-17 UniRef50_Q12IB7 Cluster: Amino acid adenylation; n=1; Shewanella... 90 4e-17 UniRef50_Q0TGF7 Cluster: Probable peptide synthetase protein; n=... 90 4e-17 UniRef50_Q0LN53 Cluster: Amino acid adenylation; n=1; Herpetosip... 90 4e-17 UniRef50_A4XD41 Cluster: Amino acid adenylation domain precursor... 90 4e-17 UniRef50_P26046 Cluster: N-(5-amino-5-carboxypentanoyl)-L-cystei... 90 4e-17 UniRef50_Q81DB7 Cluster: Peptide synthetase; n=4; Bacillus cereu... 89 5e-17 UniRef50_Q4ZVI2 Cluster: Amino acid adenylation; n=4; Pseudomona... 89 5e-17 UniRef50_Q2T4N2 Cluster: Thiotemplate mechanism natural product ... 89 5e-17 UniRef50_Q8G983 Cluster: Peptide synthetase; n=118; cellular org... 89 5e-17 UniRef50_Q0RI62 Cluster: Putative siderophore related no-ribosom... 89 5e-17 UniRef50_A3VRW5 Cluster: Probable peptide synthetase protein; n=... 89 5e-17 UniRef50_UPI00005F40EE Cluster: hypothetical protein VchoR_02002... 89 6e-17 UniRef50_Q8PKR7 Cluster: ATP-dependent serine activating enzyme;... 89 6e-17 UniRef50_Q6N4J7 Cluster: Peptide synthetase; n=1; Rhodopseudomon... 89 6e-17 UniRef50_Q52379 Cluster: Amino acid-adenylating enzyme; n=3; Pse... 89 6e-17 UniRef50_Q45R84 Cluster: Peptide synthetase; n=3; Bacteria|Rep: ... 89 6e-17 UniRef50_Q0LIS7 Cluster: Amino acid adenylation; n=1; Herpetosip... 89 6e-17 UniRef50_A6YEH2 Cluster: CmnA; n=1; Saccharothrix mutabilis subs... 89 6e-17 UniRef50_A1FGJ1 Cluster: Amino acid adenylation; n=1; Pseudomona... 89 6e-17 UniRef50_P27743 Cluster: N-(5-amino-5-carboxypentanoyl)-L-cystei... 89 6e-17 UniRef50_Q982I6 Cluster: Peptide synthetase; n=1; Mesorhizobium ... 89 8e-17 UniRef50_Q4ZMD3 Cluster: Amino acid adenylation; n=5; Proteobact... 89 8e-17 UniRef50_Q5IW60 Cluster: Phosphinothricin tripeptide synthetase ... 89 8e-17 UniRef50_Q4C639 Cluster: Amino acid adenylation; n=1; Crocosphae... 89 8e-17 UniRef50_Q2MFA3 Cluster: Putative nonribosomal peptide synthetas... 89 8e-17 UniRef50_Q02HM0 Cluster: Putative non-ribosomal peptide syntheta... 89 8e-17 UniRef50_A3IRQ7 Cluster: Amino acid adenylation; n=2; Chroococca... 89 8e-17 UniRef50_A1TW55 Cluster: Amino acid adenylation domain; n=1; Aci... 89 8e-17 UniRef50_A2QIQ8 Cluster: Remark: the terminal NRPS; n=2; Aspergi... 89 8e-17 UniRef50_A1CLY8 Cluster: Hybrid NRPS/PKS enzyme, putative; n=1; ... 89 8e-17 UniRef50_Q4ZV21 Cluster: Non-ribosomal peptide synthase:Amino ac... 88 1e-16 UniRef50_Q1D437 Cluster: Non-ribosomal peptide synthetase/polyke... 88 1e-16 UniRef50_A1G7D3 Cluster: Amino acid adenylation domain; n=3; Act... 88 1e-16 UniRef50_Q6Q883 Cluster: SirP; n=2; Ascomycota|Rep: SirP - Lepto... 88 1e-16 >UniRef50_Q402E3 Cluster: Ebony; n=4; Neoptera|Rep: Ebony - Papilio xuthus Length = 861 Score = 254 bits (622), Expect = 1e-66 Identities = 119/181 (65%), Positives = 143/181 (79%) Frame = +3 Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHN 182 Q+ I T+PIG P+ N +YLLDE M RE EPGEV VAG NLA GYV G+ P +F +N Sbjct: 352 QLDIHPTIPIGKPVDNCAIYLLDEEMNPAREAEPGEVWVAGSNLAAGYVGGQAPEKFCYN 411 Query: 183 PHNTHPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 PH +HP+F KLYRTGDFG+L KG+ILYAGR DSQVKIRGHRVDL EV+ AVS + ++ Sbjct: 412 PHASHPDFGKLYRTGDFGVLHKGMILYAGRTDSQVKIRGHRVDLLEVETAVSAVEGIEKA 471 Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIETVPVLVNGK 542 VVLCYG+E NPE+LAFVTI+P+AR+SA +IEA L +SLT YM+PQVI IE VP+LVNGK Sbjct: 472 VVLCYGLERGNPEVLAFVTISPDARLSAHHIEAALKNSLTHYMLPQVIVIEAVPLLVNGK 531 Query: 543 V 545 V Sbjct: 532 V 532 >UniRef50_Q9GSP4 Cluster: Mutant e4 ebony; n=2; Drosophila|Rep: Mutant e4 ebony - Drosophila melanogaster (Fruit fly) Length = 735 Score = 200 bits (489), Expect = 1e-50 Identities = 96/182 (52%), Positives = 123/182 (67%), Gaps = 1/182 (0%) Frame = +3 Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHN 182 Q+ ++ VPIG+P+SN VYLLD + R V+ GE GE+ +G NLA GYV G+DP RF+ N Sbjct: 216 QLSLYDNVPIGIPLSNTVVYLLDADYRPVKNGEIGEIFASGLNLAAGYVNGRDPERFLEN 275 Query: 183 PHNTHPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 P +A+LYRTGD+G L G I+Y GR DSQVKIRGHRVDL EV+ V+ +P VD Sbjct: 276 PLAVEKKYARLYRTGDYGSLKNGSIMYEGRTDSQVKIRGHRVDLSEVEKNVAELPLVDKA 335 Query: 363 VVLCYGVESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQVIEIETVPVLVNG 539 +VLCY + ILAFV + +A M + +EA L L DYM PQV+ +E VP+LVNG Sbjct: 336 IVLCYHAGQVDQAILAFVKLRDDAPMVTETQMEARLKDKLADYMTPQVVILEHVPLLVNG 395 Query: 540 KV 545 KV Sbjct: 396 KV 397 >UniRef50_O76858 Cluster: Ebony protein; n=18; Diptera|Rep: Ebony protein - Drosophila melanogaster (Fruit fly) Length = 879 Score = 200 bits (489), Expect = 1e-50 Identities = 96/182 (52%), Positives = 123/182 (67%), Gaps = 1/182 (0%) Frame = +3 Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHN 182 Q+ ++ VPIG+P+SN VYLLD + R V+ GE GE+ +G NLA GYV G+DP RF+ N Sbjct: 360 QLSLYDNVPIGIPLSNTVVYLLDADYRPVKNGEIGEIFASGLNLAAGYVNGRDPERFLEN 419 Query: 183 PHNTHPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 P +A+LYRTGD+G L G I+Y GR DSQVKIRGHRVDL EV+ V+ +P VD Sbjct: 420 PLAVEKKYARLYRTGDYGSLKNGSIMYEGRTDSQVKIRGHRVDLSEVEKNVAELPLVDKA 479 Query: 363 VVLCYGVESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQVIEIETVPVLVNG 539 +VLCY + ILAFV + +A M + +EA L L DYM PQV+ +E VP+LVNG Sbjct: 480 IVLCYHAGQVDQAILAFVKLRDDAPMVTETQMEARLKDKLADYMTPQVVILEHVPLLVNG 539 Query: 540 KV 545 KV Sbjct: 540 KV 541 >UniRef50_UPI0000DB6BFA Cluster: PREDICTED: similar to ebony CG3331-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to ebony CG3331-PA - Apis mellifera Length = 860 Score = 168 bits (409), Expect = 6e-41 Identities = 76/173 (43%), Positives = 113/173 (65%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 VPIG P+ N +Y+++++MR + +GE GE+ VAG NLA GY+ + +F NP+ Sbjct: 354 VPIGKPLDNCVIYIVNKDMRLIPQGEVGELIVAGRNLATGYIHNNESRKFQDNPYTIDLE 413 Query: 204 FAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGV 383 ++++Y TGD+ + KGVI+Y GR DSQ+K+RGHRVDL EV+ +S I +D +VLCY Sbjct: 414 YSRIYCTGDYAKISKGVIMYEGRVDSQIKVRGHRVDLTEVEKVISRISEIDGVIVLCYKP 473 Query: 384 ESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIETVPVLVNGK 542 + ++AFVTI ++ IE L S L YM+P+VI +E +P+L NGK Sbjct: 474 GELSQSLVAFVTIAKDSSTCVSKIETFLQSMLPIYMLPRVIIVENIPLLTNGK 526 >UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2; Cyanobacteria|Rep: Amino acid adenylation - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 2791 Score = 124 bits (300), Expect = 1e-27 Identities = 62/179 (34%), Positives = 109/179 (60%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194 ++PIG PISN +Y+L+ +++ V G PGE+ + GF +++GY+ + +FI +P + Sbjct: 2569 SIPIGRPISNTQIYILNSHLQPVPIGTPGEIYIGGFGVSKGYLNRPELTIEKFIPDPFSK 2628 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 PN A+LY+TGD L G I + GR D Q+K+RG+R++L E++ + P V +V+ Sbjct: 2629 QPN-ARLYKTGDQARYLSNGNIEFIGRIDHQIKLRGYRIELGEIEAVLQQHPQVKQAIVI 2687 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545 +S N +++A++ + + + L + L +YMIP VI +I+T+P+ NGK+ Sbjct: 2688 ARNSDSENQQLVAYIVPSQTQDSLTNELRSFLQTKLPNYMIPSVILQIDTLPLTPNGKI 2746 Score = 87.4 bits (207), Expect = 2e-16 Identities = 53/156 (33%), Positives = 84/156 (53%), Gaps = 4/156 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG I+N +Y+LD++++ V G PGE+ + G +ARGY+ +FI NP + + Sbjct: 1463 VPIGRAIANTQIYILDKHLQPVPIGVPGELHIGGVGVARGYLNQPQLTAEKFIVNPFSNN 1522 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 N +LY+TGD G I Y GR D QVK+RG R++L E++ ++ P V VV+ Sbjct: 1523 SN-NRLYKTGDLARYHTDGSIEYLGRLDDQVKLRGFRIELTEIESVLTQHPDVRKAVVVM 1581 Query: 375 YGVESSNPEILAFVTINPEARMSAKN-IEAELTSSL 479 + +++ N +N ++ ELT L Sbjct: 1582 RETSAVKRQVVLNPPENNSEITDLRNFLKGELTEEL 1617 Score = 47.2 bits (107), Expect = 2e-04 Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 1/107 (0%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNT 194 + V G P+++ + ++D + + + + GE+ VAG ++A+GY + + Sbjct: 372 ILVGCGQPLADLKIVIVDPQTLSACSDRQVGEIWVAGASVAQGYWHQPEQTESTFKAYTK 431 Query: 195 HPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV 335 RTGD G L G + GR + IRG Q++++ V Sbjct: 432 DTKEGPFLRTGDLGFLQDGELFITGRLKDLIIIRGRNYYPQDIENTV 478 Score = 33.9 bits (74), Expect = 2.5 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 1/56 (1%) Frame = +3 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 VES+ +++A+ + + + L L DYMIP I ++ +PV NGK+ Sbjct: 1619 VESTTKQLIAYCVCRHQPAPNITKLRRFLGEKLPDYMIPATFIMLDALPVTANGKL 1674 >UniRef50_Q08787 Cluster: Surfactin synthetase subunit 3; n=9; Bacillus|Rep: Surfactin synthetase subunit 3 - Bacillus subtilis Length = 1274 Score = 124 bits (299), Expect = 1e-27 Identities = 71/179 (39%), Positives = 106/179 (59%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++PIG PISN VY+L+E + G GE+C++G +++GYV D +FI NP Sbjct: 776 SLPIGKPISNASVYILNEQSQLQPFGAVGELCISGMGVSKGYVNRADLTKEKFIENPFKP 835 Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 LYRTGD L G I YAGR D QVKIRGHR++L+E++ + P V + VV+ Sbjct: 836 GET---LYRTGDLARWLPDGTIEYAGRIDDQVKIRGHRIELEEIEKQLQEYPGVKDAVVV 892 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 ES + I A++ +N ++SA++++A L L YM+PQ ++ +P+ NGKV Sbjct: 893 ADRHESGDASINAYL-VN-RTQLSAEDVKAHLKKQLPAYMVPQTFTFLDELPLTTNGKV 949 >UniRef50_Q0LPK1 Cluster: Amino acid adenylation; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Amino acid adenylation - Herpetosiphon aurantiacus ATCC 23779 Length = 1714 Score = 121 bits (292), Expect = 9e-27 Identities = 65/179 (36%), Positives = 104/179 (58%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+PIG PI N ++LD M+ V G GE+ + G LARGY R D RF+ +P +T Sbjct: 333 TIPIGYPIDNLTTWVLDAQMQPVAVGRSGELYIGGMGLARGYQRQPDRSAERFVPDPFST 392 Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +LY+TGD +L G +L+ R D Q+K+RG+R++L E+ + P + VV+ Sbjct: 393 QPG-TRLYKTGDRVRLLANGALLFLDRIDQQIKLRGYRIELGEIQAGLERHPQIRQSVVV 451 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ +++A+V PEAR+ + + A L + L YM+P + +E +P+L NGK+ Sbjct: 452 GQLDQTKTLQLVAYVVPMPEARIPIEQLRALLKAQLPRYMLPSAFVILERLPLLANGKL 510 Score = 93.5 bits (222), Expect = 3e-18 Identities = 57/177 (32%), Positives = 92/177 (51%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG I VY+LD ++ + G G++ +AG LA GY+ D F+ NP + P Sbjct: 1402 PIGRAIQQMAVYVLDRELQPMPTGVIGDIYIAGIGLALGYIAKPDLTAEVFLPNPLSAEP 1461 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YR+GD G L G +++ GR+D QVKIRG R++L E+ V V VV Y Sbjct: 1462 GM-RMYRSGDRGRYLADGSLMFVGRSDRQVKIRGMRIELNEIRTCVLQHAQVHEAVVNIY 1520 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + NP+I+A+V ++ ++ + L M PQ + ++ +P+ N K+ Sbjct: 1521 NDQPDNPQIVAYVVPTKGQLLTEASLRTYIGQKLPLAMQPQAFVLLDRLPLTANDKL 1577 >UniRef50_A1KQR7 Cluster: RhiB protein; n=1; Burkholderia rhizoxina|Rep: RhiB protein - Burkholderia rhizoxina Length = 6722 Score = 121 bits (292), Expect = 9e-27 Identities = 67/177 (37%), Positives = 103/177 (58%), Gaps = 4/177 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI N +Y+LD + V GE GE+C+ G LARGY+ + +FI +P + Sbjct: 256 VPIGRPIDNIQIYILDSEAKPVPIGETGELCIGGLGLARGYLNRPELTAEKFIRDPFSGE 315 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A+LYRTGD L G I GR DSQVK+RG R++L E++ A+ + P +D+ VL Sbjct: 316 AG-ARLYRTGDKARFLSNGEIELLGRFDSQVKLRGFRIELGEIESALKSHPAIDDAAVLV 374 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGK 542 S++P+++AFV + K + + + L +YM+P ++ I+ +PV +GK Sbjct: 375 KDPGSADPKLVAFVVAQ---GLDKKAVRDFIKARLPEYMVPNLVSFIDQIPVTAHGK 428 >UniRef50_Q8VQF9 Cluster: Peptide synthetase XpsA; n=1; Xenorhabdus bovienii|Rep: Peptide synthetase XpsA - Xenorhabdus bovienii Length = 1089 Score = 120 bits (290), Expect = 2e-26 Identities = 67/183 (36%), Positives = 109/183 (59%), Gaps = 4/183 (2%) Frame = +3 Query: 9 HIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN 182 HI L VPIG PI N +Y+LD++ + V G GE+ +AG +ARGY+ + RFI + Sbjct: 797 HIGL-VPIGHPIDNTQIYILDKHDQPVPIGVIGEIYIAGAGVARGYLNKPELTAERFIRD 855 Query: 183 PHNTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359 P + HP+ ++Y+TGD G L G I Y GR D QVKIRG+R++L E++ ++ V N Sbjct: 856 PFSQHPDM-RMYKTGDIGRWLADGSIDYLGRNDFQVKIRGNRIELGEIEARLAQSDGVQN 914 Query: 360 CVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536 +V+ ++ + ++A++ P +S + ++ SL DYMIP + ++ P+ +N Sbjct: 915 VIVIAREYDAGDTRLVAYLIPKPGVTLSIPALREQVGGSLPDYMIPSAFVMLDAFPLTLN 974 Query: 537 GKV 545 GK+ Sbjct: 975 GKL 977 >UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular organisms|Rep: CDA peptide synthetase I - Streptomyces coelicolor Length = 7463 Score = 119 bits (287), Expect = 4e-26 Identities = 63/178 (35%), Positives = 101/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P +N VY+LD +R V G GE+ +AG LARGY+ RF NPH++ Sbjct: 4565 VPIGRPFANTQVYVLDSALRPVAPGVTGELYLAGEQLARGYLGRPALTAERFTANPHSST 4624 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YRTGD + G + Y GRAD Q+K+RGHR++ E++ ++ + V Sbjct: 4625 PG-ARMYRTGDLAHWNHHGHLTYDGRADHQIKLRGHRIEPGEIEATLTAQTGITQATVQL 4683 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + ++A++ +N K + LTS+L DYM+P ++ ++ +P+ NGK+ Sbjct: 4684 REDQPGDQRLVAYLVVNDSTEYDEKTVRDALTSALPDYMVPSALVTLDALPLTPNGKL 4741 Score = 111 bits (266), Expect = 1e-23 Identities = 65/177 (36%), Positives = 100/177 (56%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHP 200 PIG P++N+ VY+LD +R V G PGE+ AG +LARGY R RF+ NP P Sbjct: 3070 PIGSPVANSAVYVLDAALRPVPPGVPGELYAAGAHLARGYHDRRALTAERFVANPFG-EP 3128 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++LYRTGD G + Y GRAD+QVKIRG R++ E++ ++ P + V+ Sbjct: 3129 G-SRLYRTGDLVRWRPDGQLEYLGRADTQVKIRGLRIEPTEIEAVITERPHLARAAVIVR 3187 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V P A + + A L +L D+MIP + ++ +P+ +NGK+ Sbjct: 3188 EDRPGDRRLVAYVVPEPGATVDTAELRAALRETLPDHMIPTAFVVLDALPLTLNGKL 3244 Score = 110 bits (264), Expect = 2e-23 Identities = 61/178 (34%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P +N VY+LD +R V G GE+ +AG LARGY+ RF NPH++ Sbjct: 5605 VPIGRPFANTQVYVLDSALRPVAPGVTGELYLAGEQLARGYLGRPALTAERFTANPHSST 5664 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YRTGD + G + Y GRAD Q+K+RGHR++ E++ ++ + V Sbjct: 5665 PG-ARMYRTGDLAHWNHDGHLTYDGRADHQIKLRGHRIEPGEIETTLTAQTGITQTTVQL 5723 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A++ +N + L S+L DYM P + ++ +P+ NGK+ Sbjct: 5724 REDTPGDQRLVAYLVVNDSTEYDEPTLRDALASALPDYMRPSAYVTLDALPLTPNGKL 5781 Score = 91.1 bits (216), Expect = 2e-17 Identities = 59/178 (33%), Positives = 93/178 (52%), Gaps = 6/178 (3%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT--H 197 IGV I + VY+LD+ +R G GE+ VAG LARGY+ RF +P+ Sbjct: 2004 IGVNIPDLRVYVLDDRLRPTAPGVTGEMYVAGAGLARGYLGRPALTADRFPADPYAALFG 2063 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G + Y GRAD QVKIRG R++ E++ ++ P VD+ V+ Sbjct: 2064 ERGTRMYRTGDLARRRTDGGLDYLGRADQQVKIRGFRIEPGEIEAVLAAHPAVDDVAVVA 2123 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 +P ++A+V A +A+ + L D+M+P + ++ +P+ NGK+ Sbjct: 2124 REDVQGDPRLVAYVVTGSGA--TARALHDHAAGHLPDHMLPSAFVTLDVLPLTPNGKL 2179 Score = 90.2 bits (214), Expect = 3e-17 Identities = 56/181 (30%), Positives = 95/181 (52%), Gaps = 6/181 (3%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++P+G N Y+LD ++ V G PGE+ ++G LARGY+ D RF+ +P+ Sbjct: 6685 SLPVGRATGNTRAYVLDRYLQPVPAGVPGELFISGSGLARGYLDRPDLTCERFVADPYG- 6743 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + ++YRTGD + G + Y RAD QVKIRG RV+L E++ ++T P + V+ Sbjct: 6744 -GSGERMYRTGDLVRYNAAGELEYLARADDQVKIRGFRVELGEIEAVLATRPELAQAAVV 6802 Query: 372 CYGVESSNPEILAFV--TINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542 + ++ +V + + + A +L DYM+P + + T+P+ NGK Sbjct: 6803 VREDRPGDRRLVGYVVAAAGRDGEVDPDALRAFSRQALPDYMVPSAFVVLGTLPLTANGK 6862 Query: 543 V 545 + Sbjct: 6863 L 6863 Score = 85.4 bits (202), Expect = 8e-16 Identities = 50/133 (37%), Positives = 75/133 (56%), Gaps = 3/133 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 VPIG P+ N +Y+LD +R V G PGE+ +AG LARGY+ RF +PH Sbjct: 792 VPIGRPVWNTRMYVLDAALRPVPAGVPGELYIAGVQLARGYLGRPALSAERFTADPHGA- 850 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +++YRTGD + G + Y GRAD QVK+RG R++L E++ A+ P + V+ Sbjct: 851 PG-SRMYRTGDLARWNHDGSLDYLGRADHQVKLRGFRIELGEIEAALVRQPEIAQAAVVL 909 Query: 375 YGVESSNPEILAF 413 + ++A+ Sbjct: 910 REDRPGDQRLVAY 922 >UniRef50_Q8VQF8 Cluster: Peptide synthetase XpsB; n=1; Xenorhabdus bovienii|Rep: Peptide synthetase XpsB - Xenorhabdus bovienii Length = 3316 Score = 119 bits (287), Expect = 4e-26 Identities = 61/179 (34%), Positives = 108/179 (60%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+ IG PI+N +Y+LD + V G GE+ + G +ARGY+ + RF+ +P++ Sbjct: 3011 TLSIGRPIANTRIYILDTRGQPVPTGVTGEIYIGGAGVARGYLNRPELTTERFVSDPYSE 3070 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 PN A++YRTGD G G I+Y GR D QVK+RG R++L E++ ++ V + VV+ Sbjct: 3071 QPN-ARMYRTGDLGCWQPDGTIVYLGRNDFQVKLRGFRIELGEIETQLAACLGVKDAVVV 3129 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ + ++A+V P+A + A ++ +L++ LT+YM+P + ++ P+ +GK+ Sbjct: 3130 AREEDAGDKRLVAYVIPQPDASLDAASLREQLSTHLTEYMLPSAFVILDAFPLTPSGKL 3188 Score = 117 bits (282), Expect = 2e-25 Identities = 63/178 (35%), Positives = 108/178 (60%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI+N +Y+LD+ + V G GE+ ++G +ARGY+ + RFI +P + Sbjct: 832 IPIGRPIANTRIYILDQRGQPVPIGVNGEIHISGSGVARGYLNRSELTAERFIQDPFSDI 891 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++Y+TGD G L G I Y+GR D QVKIRG R++L E++ ++T V + VV+ Sbjct: 892 PG-ARMYKTGDLGRWLPDGTISYSGRNDFQVKIRGFRIELGEIEAQLATCAGVKDAVVIV 950 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ + ++A++ A ++A ++ +L+ +L DYM+P + +E P+ NGK+ Sbjct: 951 REDDNGDKRLVAYLIPQSGAILNAASLREQLSVNLADYMLPSAFVTLEAFPLNQNGKI 1008 Score = 107 bits (257), Expect = 2e-22 Identities = 57/179 (31%), Positives = 102/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++ IG P+ N +VY+LD + V G GE+ + G +ARGY+ + RF+ +P Sbjct: 1905 SLSIGRPLINTHVYILDTQGQPVPIGVTGEIYIGGAGVARGYLNRPELTAERFVSDPFRE 1964 Query: 195 HPNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P+ A++YRTGD G G I+Y GR D QVKIRG R++L E++ ++ V + VV+ Sbjct: 1965 QPH-ARMYRTGDLGCWRPDGTIVYLGRNDFQVKIRGFRIELGEIESQLAACTGVSDAVVV 2023 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 S + ++A++ + + A ++ ++++ L +YM+P + ++ P+ NGK+ Sbjct: 2024 AREEGSGDKRLVAYLVPKSDVTLDAASLREQVSTHLAEYMLPSAFVILDAFPLNPNGKL 2082 >UniRef50_Q4C3C2 Cluster: Amino acid adenylation; n=1; Crocosphaera watsonii WH 8501|Rep: Amino acid adenylation - Crocosphaera watsonii Length = 1539 Score = 119 bits (287), Expect = 4e-26 Identities = 64/179 (35%), Positives = 103/179 (57%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PI+N Y+LD N++ V G PGE+ + G LARGY+ + RFI NP Sbjct: 777 SVPIGRPIANTQTYILDVNLQPVPVGVPGELYLGGVQLARGYLNRPELTAERFIENPFRE 836 Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + +++LY+TGD L G I Y GR D+QVKIRG R++L E++ ++ V VV+ Sbjct: 837 NFGYSRLYKTGDLVCYLPDGNIEYLGRLDNQVKIRGLRIELGEIEAQIAQYETVKEAVVI 896 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A++ E+ +++ + L L +YMIP + +E +P+ NGK+ Sbjct: 897 AREEIAGDKRLVAYLVPQEESTVNSSKLRKFLREKLPNYMIPSAFVTLEELPLTPNGKI 955 >UniRef50_Q0B1F6 Cluster: Amino acid adenylation domain; n=2; Bacteria|Rep: Amino acid adenylation domain - Burkholderia cepacia (strain ATCC 53795 / AMMD) Length = 3018 Score = 119 bits (287), Expect = 4e-26 Identities = 63/178 (35%), Positives = 102/178 (57%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPHNTH 197 VP+G PI N +Y++D M G PGE+CV+G + RGY+ + R F+ +P Sbjct: 762 VPVGKPIRNVRIYVVDPQMNLCPIGVPGELCVSGVAVGRGYLNNEAGTREAFLEDPFRAE 821 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRT D G L G I+ GR D Q+KIRG+R++L E+D+A++ IP + L Sbjct: 822 SG-VRMYRTRDIGCYLPDGSIVLHGRKDHQLKIRGYRIELGEIDNALAAIPEIRQAAALD 880 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 Y ++ + A+V A +S I A L+++L DYM+P + + ++ +P+ NGK+ Sbjct: 881 YRDDAGRAALCAYVAFRAGASLSDAEIAAALSATLPDYMVPGIYVVLDALPLSGNGKI 938 Score = 98.3 bits (234), Expect = 1e-19 Identities = 57/178 (32%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPHNTH 197 +PIG PI N VY++D +M G GE+C+ G + RGY+ + R F +P + Sbjct: 2275 IPIGRPIENLRVYVVDADMNLCPVGVKGEICIGGAGVGRGYLFDEARTRAVFRDDPFSPE 2334 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LYRTGD G G + + GR D QVKIRG+R++L E++ A++ + + N VV+ Sbjct: 2335 PG-ARLYRTGDVGCFGSDGNLHFFGRRDFQVKIRGYRIELGEIETALTGLAGISNAVVVV 2393 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + + + + + K + L L +M+P + + +PV+ NGK+ Sbjct: 2394 RDTPDAEKTLCGYAS---GTGWTPKRLRDALRDKLPAHMVPDTLMLLSALPVMPNGKI 2448 >UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibiotic biosynthesis; n=1; Photorhabdus luminescens subsp. laumondii|Rep: Similar to proteins involved in antibiotic biosynthesis - Photorhabdus luminescens subsp. laumondii Length = 3270 Score = 118 bits (285), Expect = 7e-26 Identities = 67/179 (37%), Positives = 105/179 (58%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+ IG PI N ++LLD+N + V G GE+CVAG +ARGY+ + RFI NP + Sbjct: 1902 TLSIGHPIQNTAIFLLDKNQQLVPFGAVGEICVAGDGVARGYINKEQLTRERFIDNPFVS 1961 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + KLYRTGD G G I Y GR D QVKIRG R++L E++ + ++P + + VV+ Sbjct: 1962 --RYPKLYRTGDLGRYSLAGDIQYYGRDDHQVKIRGFRIELGEIETRLRSLPTIRDAVVI 2019 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E ++ + A++T++ + +++ I L+ L YM+P + +E +P+ N KV Sbjct: 2020 AREDEPAHKYLAAYITLDGQQKVA--EIRHLLSQQLPSYMVPAAFVVLEEIPLTANRKV 2076 Score = 106 bits (254), Expect = 4e-22 Identities = 58/178 (32%), Positives = 100/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V IG+P++N +YLLDE ++ V G GE+ + G LA GY + +D R I+ + Sbjct: 845 VTIGLPLNNTTIYLLDEQLKPVPFGAVGELYIGGDGLAEGYFKREDLTTERLINLTFSDG 904 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 AK+Y+TGD +G ++Y GR D QVK+RGHR++L E++ ++ P + VV+ Sbjct: 905 LT-AKVYKTGDLARYTTEGSLVYLGRNDYQVKLRGHRIELGEIEQVINLFPQITRSVVVA 963 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + + +V + + A + L L YM+P+ +I++ET+P+ +N K+ Sbjct: 964 LNDQQTQQYLAGYVVAEQQIDIDA--LRQHLEQKLPAYMLPRAIIQLETLPLTLNNKI 1019 Score = 82.6 bits (195), Expect = 5e-15 Identities = 58/176 (32%), Positives = 90/176 (51%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFA 209 IG + N Y+LDE ++ V G GE+ +AG L+RGY + P + Sbjct: 2985 IGRSLPNVAGYILDEYLQPVPMGAIGELYLAGDCLSRGYY--QQPQLTAERYLDCDWVLG 3042 Query: 210 K-LYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGV 383 K +YRTGD G I Y GR D VKIRG R++L +++ +S + VV+ Sbjct: 3043 KRVYRTGDLASFHQNGEINYFGRNDHLVKIRGFRIELGDIEAQLSKFDGITGTVVIAIDT 3102 Query: 384 ESSNPEILA-FVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E+ + +++A F+ NP + I+ L++SL DYM+P + + P+ NGKV Sbjct: 3103 EAGDKQLIAYFIAANP---LDLSEIKTYLSASLPDYMLPSAYVRMAAFPLNTNGKV 3155 >UniRef50_Q2N3S9 Cluster: Hybrid nonribosomal peptide synthetase/polyketide synthase; n=2; Proteobacteria|Rep: Hybrid nonribosomal peptide synthetase/polyketide synthase - Polyangium cellulosum (Sorangium cellulosum) Length = 4641 Score = 118 bits (285), Expect = 7e-26 Identities = 66/178 (37%), Positives = 103/178 (57%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LDE R VR + GE+ +AG LARGY+ + RF+ +P + Sbjct: 1318 VPIGRPIANIRLYILDEQQRPVRPDQTGELYIAGVGLARGYLNRPELTAERFVRDPFDPS 1377 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++Y+TGD L G I + GR D Q+K+RG R++L E++ A+ V V Sbjct: 1378 PG-ARMYKTGDRAAWLPDGNIDFLGRMDGQIKLRGLRIELGEIEAALLGHEAVREAAVAV 1436 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +S +P ++A+V + A S + + L SSL YM+P Q +++ +PV +GK+ Sbjct: 1437 RDADSGDPRLVAYVVLRDGASFSPQVMRRFLESSLPRYMVPNQFVQVAGIPVTAHGKM 1494 >UniRef50_Q84BC8 Cluster: NcpA; n=5; Cyanobacteria|Rep: NcpA - Nostoc sp. ATCC 53789 Length = 3735 Score = 118 bits (284), Expect = 9e-26 Identities = 66/184 (35%), Positives = 103/184 (55%), Gaps = 10/184 (5%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP---- 185 + IG PISN +Y+LD+N++ V G PGE+ + G LARGY++ + +FI NP Sbjct: 1898 ISIGRPISNTQIYILDQNLQPVPIGVPGELHIGGAGLARGYLKRPELTQEKFIPNPFEEA 1957 Query: 186 --HNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVD 356 ++LY+TGD L G I Y GR D+QVKIRG R++L E++ A+S P V Sbjct: 1958 GGRGQEAGGSRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHPHVQ 2017 Query: 357 NCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLV 533 V+ + ++A++ P+ ++ + + L L DYM+P I I E++P+ Sbjct: 2018 ASCVIAREDTPGDKRLVAYIVPQPQVTLTISELRSNLKEKLPDYMVPSAIVILESLPLTP 2077 Query: 534 NGKV 545 NGK+ Sbjct: 2078 NGKI 2081 Score = 111 bits (266), Expect = 1e-23 Identities = 64/186 (34%), Positives = 101/186 (54%), Gaps = 12/186 (6%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI N +Y+LD+N++ V G PGE+ + G LA+GY+ + +FI NP Sbjct: 2979 IPIGRPIDNTQIYILDQNLQPVPVGVPGELHIGGAGLAKGYLNLPELTQEKFIPNPFQGS 3038 Query: 198 PNFA--------KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPC 350 +LY+TGD L G I Y GR D+QVKIRG R++L E++ A+S Sbjct: 3039 RGAGEQGSRGRERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHSD 3098 Query: 351 VDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPV 527 V VV+ N ++A+V P+ + + + L L +YM+P ++ +E++P+ Sbjct: 3099 VQTSVVIVREDIPGNKRLVAYVVPQPQITPTVSQLRSFLKEKLPEYMVPSAIVTLESLPL 3158 Query: 528 LVNGKV 545 NGK+ Sbjct: 3159 TPNGKI 3164 Score = 108 bits (259), Expect = 9e-23 Identities = 63/186 (33%), Positives = 100/186 (53%), Gaps = 12/186 (6%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 + IG PI+N +Y+LD ++ V G PGE+ + G +ARGY+ + +FI NP + Sbjct: 835 ITIGRPIANAEIYILDSQLQPVPIGVPGELHIGGAGVARGYLNRNELTQQKFIPNPFSRS 894 Query: 198 PNFA--------KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPC 350 +LY+TGD L G I Y GR D+QVKIRG R++L E++ +S P Sbjct: 895 RGAGEQGSRGRERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEATLSQHPH 954 Query: 351 VDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPV 527 V V+ + ++A++ + PE + K + + L L +YM+P I I E++P+ Sbjct: 955 VQASCVIAREDIPGDKRLIAYIVLQPEQTATVKELRSFLKEKLPEYMVPSAIAILESLPL 1014 Query: 528 LVNGKV 545 NGK+ Sbjct: 1015 TPNGKI 1020 >UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3; cellular organisms|Rep: Non-ribosomal peptide synthetase - Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) Length = 7048 Score = 117 bits (282), Expect = 2e-25 Identities = 63/180 (35%), Positives = 101/180 (56%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 LTVPIG PI+N+ +Y+LD R GE+ + G +ARGY+ D RFI +P + Sbjct: 5135 LTVPIGHPIANSQIYILDPQGRPTLLNVAGEIYIGGAGVARGYLNRPDLTAERFIPDPFS 5194 Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 + P A++Y+TGD L G I Y GR D QVK+RG R++L E++ + +P V VV Sbjct: 5195 SSPE-ARMYKTGDLARWLPDGNIDYLGRNDFQVKVRGFRIELGEIESRLMQLPGVQEAVV 5253 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A++ P+A ++ + +L L +YM+P + ++T P+ NGK+ Sbjct: 5254 AAREDIPGDTRLVAYLRSQPDAELNPTELRQQLAEHLAEYMVPSAFVTLDTFPLTPNGKI 5313 Score = 107 bits (258), Expect = 1e-22 Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD + V G GE+ + G +ARGY+ D RFI +P + Sbjct: 6220 VPIGRPIANTQLYILDTLGQPVPLGVAGELHIGGVGVARGYLNRPDLTAERFIPDPFSNQ 6279 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A+LY+TGD L G + Y GR D QVK+RG R++L E++ + P V VV+ Sbjct: 6280 HG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVA 6338 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A++ P + + +L++ L DYMIP + ++T P+ NGK+ Sbjct: 6339 REDSPGDTRLVAYLCPQPSIELMPAELRQQLSTHLADYMIPSAFVMLDTFPLTPNGKL 6396 Score = 103 bits (248), Expect = 2e-21 Identities = 61/176 (34%), Positives = 96/176 (54%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+ + YLLD + + V G GE+ + G +ARGY+ D RFI +P + P Sbjct: 825 IGRPLPDLRAYLLDPHGQPVPVGVAGELYIGGAGVARGYLNRPDLTAERFIVDPFSDSPA 884 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LY+TGD L G + Y GR D QVK+RG R++L E++ + P V VVL Sbjct: 885 -TRLYKTGDLARWLPDGTLDYLGRNDFQVKVRGFRIELGEIESRLVQCPGVQEAVVLARE 943 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A++ P+A + ++ +L++ L DYMIP + +E P+ NGK+ Sbjct: 944 DVPGDTRLVAYIQPQPKAVLEPADLRQQLSTHLADYMIPAAFVTLEAFPLTPNGKL 999 Score = 101 bits (243), Expect = 8e-21 Identities = 57/178 (32%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI N +VY+LD + G GE+ + G +ARGY+ + RFI +P++ Sbjct: 1902 LPIGKPIDNTHVYILDAKGQLAPLGVAGEMYLGGVGIARGYLNRPELTAERFIPDPYSDQ 1961 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++Y+TGD G L G I Y GR D Q+K+RG R++ E++ + V + VV+ Sbjct: 1962 PG-ARMYKTGDLGRWLADGNIEYLGRNDFQIKLRGFRIEPGEIEARLMGCSGVQDAVVIV 2020 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ ++A++ + A + + +L+ L +YM+P + +E P+ NGK+ Sbjct: 2021 REDNPNDKRLVAYIRPHVGAEIEPAALRLQLSQHLAEYMLPAAFVTLEQFPLTPNGKL 2078 Score = 101 bits (243), Expect = 8e-21 Identities = 60/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD + V G GE+ + G +ARGY+ D RFI +P Sbjct: 2981 VPIGRPIANTQLYILDTLDQPVPLGVAGELHIGGVGVARGYLNRPDLTAERFIPDPFINQ 3040 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LY+TGD L G + Y GR D QVK+RG R++L E++ + P V VV+ Sbjct: 3041 PG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVA 3099 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A++ P ++ +L L +YM+P + ++ P+ NGK+ Sbjct: 3100 REDSPGDTRLVAYLCPQPGITPDPADLRQQLGQHLAEYMVPGAFVTLDAFPLTPNGKL 3157 Score = 99.5 bits (237), Expect = 4e-20 Identities = 56/176 (31%), Positives = 91/176 (51%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P++N +Y+LD + V G GE+ + G +ARGY+ + FI +P P+ Sbjct: 4057 IGRPLANTRIYILDPQGKLVPIGATGEIHIGGVGVARGYLNRPELTAEHFIADPFTDDPD 4116 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LY+TGD G L+ G I Y GR D QVK+RG R++L E++ + V V + Sbjct: 4117 -ARLYKTGDLGRWLNDGNIDYLGRNDFQVKVRGFRIELGEIEARLIQCSGVKEAVAIARE 4175 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A++ P + + +L L +YM+P + +E P+ NGK+ Sbjct: 4176 DTPGETRLVAYLIAQPGVELVPAELRQQLAHHLAEYMVPSAFVTMEAFPLTPNGKL 4231 >UniRef50_Q0LIS9 Cluster: Amino acid adenylation; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Amino acid adenylation - Herpetosiphon aurantiacus ATCC 23779 Length = 1816 Score = 117 bits (282), Expect = 2e-25 Identities = 65/179 (36%), Positives = 101/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVP+G P+ N +Y+LD M+ +G PGE+ V G + RGY+ D RF+ NP +T Sbjct: 817 TVPLGRPLGNVQIYVLDRRMQPTPQGVPGELYVGGAGVGRGYIGRPDLTAERFVPNPFST 876 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A+LYR+GD G I + GR D QVKIRG+RV+L E++ A+ V N VV+ Sbjct: 877 EAG-ARLYRSGDLVRYQPDGAIEFLGRIDLQVKIRGYRVELSEIETAIQAQAQVANSVVI 935 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A++ ++ +I L +SL DYM+P +E++ +P+ NGK+ Sbjct: 936 LREDTPGDKRLVAYIVPEAGQSLNIGSIREALRNSLPDYMVPTAFVELDGLPLNPNGKI 994 >UniRef50_Q4KCD8 Cluster: Nonribosomal peptide synthase; n=2; cellular organisms|Rep: Nonribosomal peptide synthase - Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) Length = 6675 Score = 116 bits (280), Expect = 3e-25 Identities = 66/177 (37%), Positives = 102/177 (57%), Gaps = 4/177 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI N +++LD V G+ GE+C+ G LARGY+ + +FI +P Sbjct: 356 VPIGRPIDNIQIHILDAESHPVPIGQTGELCIGGVGLARGYLNRPELTAEKFIRDPFCAQ 415 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+ A+LYRTGD LD G I GR DSQVK+RG R++L E+++ + + P + + VVL Sbjct: 416 PD-ARLYRTGDEARFLDDGQIEVLGRFDSQVKLRGFRIELGEIENTLKSHPGISDAVVLV 474 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGK 542 S +P+++A+V + K I + + L +YM P ++ +E +PV +GK Sbjct: 475 QDPGSEDPKLVAYVVAQ---GLDKKTIRDFVKARLPEYMTPNRVQFVEQIPVTAHGK 528 >UniRef50_Q1DBW4 Cluster: Non-ribosomal peptide synthetase; n=3; Bacteria|Rep: Non-ribosomal peptide synthetase - Myxococcus xanthus (strain DK 1622) Length = 5544 Score = 116 bits (280), Expect = 3e-25 Identities = 68/179 (37%), Positives = 100/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T PIG PIS ++LLDE++ V G PG V + G ARGY+ D RFI +P T Sbjct: 4992 TFPIGRPISRVRIHLLDEHLEPVLPGLPGRVYIGGAAPARGYLGAPDMTAERFIPDPFAT 5051 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A++Y TGD +L G + + GRAD Q+KIRG RV+L E++ + P V+ VVL Sbjct: 5052 EPG-ARMYHTGDLARMLPDGRLRFLGRADHQIKIRGFRVELAEIEACLRQFPGVEEAVVL 5110 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 S ++ AF+ P+ + A + + + L YM+P ++ +E +P+ NGKV Sbjct: 5111 ARAGGSGQTQLQAFLQAPPQ-HVRADALREHVAARLPSYMVPAALVVLEALPINANGKV 5168 Score = 113 bits (273), Expect = 2e-24 Identities = 66/178 (37%), Positives = 104/178 (58%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD +R V G PGE+ + G +ARGY R + RF+ +P ++ Sbjct: 3934 VPIGRPIANTRLYVLDAALRPVPAGVPGELYIGGEGVARGYWRRPELTAERFVPDPFSSV 3993 Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YRTGD + V+ Y GR D QVK+RGHRV+ EV+ A+ +P V + VV+ Sbjct: 3994 PG-ARMYRTGDRVRLRPSDVLEYLGRVDFQVKVRGHRVEPGEVEAALIELPGVASAVVVL 4052 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++ P ++ +VT +A + + A L L +M+P ++ + +P+ NGKV Sbjct: 4053 REDGTTGPRLVGYVT-GHDAMPETEPLRASLAQRLPAHMVPSALVALAQLPLTANGKV 4109 Score = 96.7 bits (230), Expect = 3e-19 Identities = 64/179 (35%), Positives = 103/179 (57%), Gaps = 6/179 (3%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG P +N VY+LD+ ++ V G GE+ + G +ARGYV D RF+ +P + P Sbjct: 774 PIGTPKANMEVYVLDDALQPVPVGIVGELYLGGLGVARGYVGRADLTAERFVPHPFSATP 833 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LYR+GD G L GV+ + RAD QVK+RG R++L EV+ A++++P V + V Sbjct: 834 G-ARLYRSGDLGRWLPDGVLQFVSRADLQVKVRGMRIELGEVEAALASLPGVRSAAVTVQ 892 Query: 378 GVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQ--VIEIETVPVLVNGKV 545 S+ + A+V +P+A +++A L L +M+P V+ + +P+ GK+ Sbjct: 893 RRGPSDSWLAAWVVPASPDA--DVHSLQAALARLLPAFMLPSRWVLRAQ-LPLTSTGKL 948 Score = 95.9 bits (228), Expect = 5e-19 Identities = 62/180 (34%), Positives = 101/180 (56%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 + PIG P +N VY+LD+ ++ + G PGE+ + G + RGYV D RFI +P +T Sbjct: 1832 STPIGTPKANLEVYVLDDALQPLPPGVPGELYIGGTGVGRGYVGRADLTAERFIPHPFST 1891 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LYRTGD G + G + + GR D QVK+RG R++L EV+ A++++P V + V Sbjct: 1892 MPG-ARLYRTGDRGRWNADGTLGFLGRVDFQVKVRGMRIELGEVEAALASLPGVRSAAVT 1950 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ--VIEIETVPVLVNGKV 545 S+ + A+V + +++A L L +M+P V+ + +P+ GK+ Sbjct: 1951 VQRRGPSDSWLAAWV-VPASPDTDVHSLQAALARLLPAFMLPSRWVLRAQ-LPLTSTGKL 2008 Score = 77.4 bits (182), Expect = 2e-13 Identities = 57/178 (32%), Positives = 90/178 (50%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V +G P+ +Y+LD N V G PGE+ + G L RGY D RFI + + Sbjct: 2877 VRLGRPLDRCRLYVLDANGAPVPPGVPGELYIGGTCLGRGYRDRPDLTAERFIPDAFSGR 2936 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD + G + + GR D QVK+RG RV+L+EV+ A+ P V V+ Sbjct: 2937 EG-GRLYRTGDRVRWNGDGSLGFLGRTDFQVKVRGVRVELEEVEAALLRQPGVRQASVVV 2995 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIET-VPVLVNGKV 545 G + + + AF+ + A + L+ +L + ++P + T +P+ +GKV Sbjct: 2996 RGTQ-RDARLEAFLVLEGTAAGVESRLREGLSRALPEALVPSRFTVLTALPMTTSGKV 3052 >UniRef50_O68006 Cluster: Bacitracin synthetase 1 (BA1) [Includes: ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent cysteine adenylase (CysA) (Cysteine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase); ATP-dependent glutamate adenylase (GluA) (Glutamate activase); ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); Glutamate racemase (EC 5.1.1.3)]; n=7; cellular organisms|Rep: Bacitracin synthetase 1 (BA1) [Includes: ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent cysteine adenylase (CysA) (Cysteine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase); ATP-dependent glutamate adenylase (GluA) (Glutamate activase); ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); Glutamate racemase (EC 5.1.1.3)] - Bacillus licheniformis Length = 5255 Score = 116 bits (280), Expect = 3e-25 Identities = 68/178 (38%), Positives = 105/178 (58%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI N VY+L+++++ G GE+C+AG LARGYV + +FI NP Sbjct: 2424 IPIGKPIDNVKVYILNKDLQLCPLGASGELCIAGEGLARGYVNRPELTREKFIGNPF--V 2481 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD +L G I + GR D QVKIRG+R++ E+++ + ++ V+ Sbjct: 2482 PG-ERMYRTGDLAKMLPDGNIQFLGRVDQQVKIRGYRIEPGEIENRLLKYEKIEEAAVIA 2540 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 +P + A+VT+ E + + I A L SL DYMIPQ ++++ +P+ VNGKV Sbjct: 2541 REDGDHDPYLCAYVTVKKE--VEPEKIRAFLKKSLPDYMIPQYFVQLDGLPLTVNGKV 2596 Score = 111 bits (266), Expect = 1e-23 Identities = 66/179 (36%), Positives = 103/179 (57%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+PIG P++N V ++DE + V G PGE+C+AG L++GY+ ++ +FI PH Sbjct: 346 TIPIGSPLANTSVLIMDEAGKLVPIGVPGELCIAGDGLSKGYLNREELTAEKFI--PHPF 403 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +LY+TGD L G I + GR D QVKIRG R++L E++ + ++ +V Sbjct: 404 IPG-ERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVT 462 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E S P I A++T N E +S ++ L L +YMIP ++++ +P+ NGKV Sbjct: 463 VREDEESRPYICAYITANRE--ISLDELKGFLGEKLPEYMIPAYFVKLDKLPLTKNGKV 519 Score = 111 bits (266), Expect = 1e-23 Identities = 66/179 (36%), Positives = 103/179 (57%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+PIG P++N V ++DE + + G PGE+C+AG L++GY+ ++ +FI PH Sbjct: 4973 TIPIGSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFI--PHPF 5030 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +LY+TGD L G I + GR D QVKIRG R++L E++ + ++ +V Sbjct: 5031 IPG-ERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVT 5089 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E S P I A++T N E +S ++ L L DYMIP ++++ +P+ NGKV Sbjct: 5090 VREDEESRPYICAYITANRE--ISLDELKGFLGEKLPDYMIPAYFVKMDKLPLTKNGKV 5146 Score = 110 bits (264), Expect = 2e-23 Identities = 61/179 (34%), Positives = 102/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNT 194 ++P G P++N +Y+L++N + G GE+ + G +A GY+ K H FI Sbjct: 1385 SIPYGKPLANQKIYVLNQNKQLCPVGVEGELYIGGAGVASGYIHDQEKTEHSFIQ----- 1439 Query: 195 HPNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 H +Y+TGD+G+L + G + + GR DSQVKIRG+RV++ E+++ + + + V+ Sbjct: 1440 HQELGYIYKTGDYGVLKEDGYVEFLGRKDSQVKIRGYRVEMGEIENTLVSHQEITKASVI 1499 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 Y + AFV E +S +++ L +L DYMIP + ++IE +P+ VNGKV Sbjct: 1500 DYTSPDGIKNLYAFVV--AENAISQLDVKEFLQKTLPDYMIPAKFVQIEEIPLTVNGKV 1556 Score = 105 bits (252), Expect = 7e-22 Identities = 60/179 (33%), Positives = 103/179 (57%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++PIG P+ N +Y++D+ +R + G GE+C+AG +ARGYV + +F+ +P Sbjct: 3464 SIPIGRPLLNTSIYIVDKELRPLPVGIAGELCIAGEGVARGYVNRPELTAEKFVDHPF-- 3521 Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P K+Y+TGD + L G I + GRAD QVKIRG+R++L EV+ + T + V+ Sbjct: 3522 EPG-KKMYKTGDLAMWLPDGQIEFLGRADHQVKIRGYRIELGEVEQQLLTHEKIKEAAVI 3580 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++ N + A++ + E + A ++ L + DYMIP ++++ +P +GKV Sbjct: 3581 AGKDQNGNSYLCAYIASDKE--LPAADVRQFLEREMPDYMIPSYFVKLDRLPRTPSGKV 3637 >UniRef50_Q2VQ15 Cluster: Nonribosomal peptide synthetase C; n=3; Brevibacillus texasporus|Rep: Nonribosomal peptide synthetase C - Brevibacillus texasporus Length = 4617 Score = 116 bits (279), Expect = 4e-25 Identities = 64/178 (35%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P++N VY+L+EN + G PGE+CV G +ARGY+ + RF+ NP Sbjct: 1811 VPIGRPLNNTSVYILNENNQPQPIGVPGELCVGGAGIARGYLNRPELTAERFVDNPFLVG 1870 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD L G I Y GR D QVKIRGHR++L E++ ++ P + V++ Sbjct: 1871 D---RMYRTGDMARFLPDGNIEYIGRMDEQVKIRGHRIELGEIEKSLLEYPAISEAVLVA 1927 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E + + A+V + + + + +L +YM+P +E+E +P+ NGKV Sbjct: 1928 KRDEQGHSYLCAYVVSTDQ--WTVAKVRQHILEALPEYMVPSYFVELEKLPLTSNGKV 1983 Score = 112 bits (269), Expect = 6e-24 Identities = 63/178 (35%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P++N VY+L+EN + G PGE+CV G +ARGY+ + RF+ NP + Sbjct: 2846 VPIGRPLNNTSVYVLNENNQLQPIGVPGELCVGGAGIARGYLNRPELTAERFVENPFVSG 2905 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD L G + Y GR D QVK+RG+R++L E++ + P + V+L Sbjct: 2906 D---RMYRTGDLARWLPDGSMEYLGRMDEQVKVRGYRIELGEIETRLLEHPSISAAVLLA 2962 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E + + A++ N + + L+ +L +YM+P +E+E +P NGKV Sbjct: 2963 KQDEQGHSYLCAYIVAN--GVWTVAELRKHLSEALPEYMVPTYFVELEQIPFTSNGKV 3018 Score = 97.9 bits (233), Expect = 1e-19 Identities = 60/179 (33%), Positives = 93/179 (51%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PI+N Y+++ + + G GE+C+ G +A GY+ + F+ NP Sbjct: 775 SVPIGRPINNTKAYIVNTDGQPQPIGVVGELCIGGEGVACGYLNRPELTKKHFVDNPFVL 834 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 ++Y TGD L G I Y GR D QVKIRGHR++L E++ + P + V+L Sbjct: 835 GE---RMYCTGDLARFLPDGNIEYIGRMDEQVKIRGHRIELGEIEKVLLQHPAISETVLL 891 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E + + A++ + + + L SL +YM+P IEIE +P+ NGKV Sbjct: 892 AKRDEQGHSYLCAYIV--GQVFWTVTELRQHLMESLPEYMVPSYFIEIEKLPLTANGKV 948 Score = 91.1 bits (216), Expect = 2e-17 Identities = 60/176 (34%), Positives = 88/176 (50%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPHNTHPN 203 IG P+ N Y+++ N + G PGE+C+ G +A GY + R F+ NP Sbjct: 3874 IGKPVLNKKAYIINPNYQLQPIGVPGELCIGGVGIAPGYWNRPELTREKFVDNPF---AQ 3930 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++Y+TGD L G I + GR D QVKIRGHR++L E++ + V VVL Sbjct: 3931 GERMYKTGDLVRWLPDGNIEFLGRIDDQVKIRGHRIELGEIETRLLEHEQVIEAVVLARE 3990 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E + A++ E + + L +L DYMIP IE+E P+ +GKV Sbjct: 3991 DEQGQAYLCAYLVAADE--WTVAELRKHLGKTLPDYMIPAYFIELEEFPLTPSGKV 4044 >UniRef50_Q4ZT67 Cluster: Amino acid adenylation; n=15; Bacteria|Rep: Amino acid adenylation - Pseudomonas syringae pv. syringae (strain B728a) Length = 13537 Score = 116 bits (278), Expect = 5e-25 Identities = 65/178 (36%), Positives = 104/178 (58%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTH 197 +PIG PI N+ VY+LD + V G GE+ + G +A+GY+ + + +F+ NP + Sbjct: 855 IPIGRPIGNSQVYVLDTLRQPVAVGVAGELYIGGQGVAKGYLNRPELNATQFVANPFSDD 914 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A LYRTGD G + G++ Y GR D QVKIRG R++L E++ + P V VVL Sbjct: 915 AG-ALLYRTGDLGRWNADGIVEYLGRNDDQVKIRGFRIELGEIEARLVECPGVREAVVLA 973 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ES++ ++A+V + +SA + EL +SL +YM+P + +++ P+ NGK+ Sbjct: 974 RQDESAHKRLVAYVVGEENSALSAVELRRELAASLAEYMVPSAFMVLDSFPLTANGKL 1031 Score = 111 bits (267), Expect = 1e-23 Identities = 64/177 (36%), Positives = 97/177 (54%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+ N YLLDE + V G GE+ + G +ARGY+ D RF+ +P + P Sbjct: 1929 IGKPVGNTRFYLLDEQQQPVPLGVAGEIYIGGAGVARGYLNRDDLTAERFLLDPFSQQPA 1988 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD G L G I Y GR D QVKIRG R++L E+D ++ P V VV Sbjct: 1989 -ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTARE 2047 Query: 381 VESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ T ++ + N+ + L L +YM+P + + +E +P+ NGK+ Sbjct: 2048 DIPGDKRLVAYYTLVSGHTSVDIDNLRSHLQEKLPEYMVPAIYVLLEAMPLTPNGKL 2104 Score = 110 bits (265), Expect = 2e-23 Identities = 59/176 (33%), Positives = 101/176 (57%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTHPN 203 IG P++N +YLLDE+ + V G GE+ + G +ARGY+ ++ + RF+ +P + P+ Sbjct: 10575 IGKPMANTRIYLLDEHQQPVPYGVAGEIFIGGDGVARGYLNLEEVNAERFLADPFSNSPD 10634 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++Y+TGD + G I Y GR D QVK+RG R++L E++ + V VV+ Sbjct: 10635 -ARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCKGVKEAVVIARE 10693 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+V P+A + A ++ AEL L +YM+P + ++ +P+ N K+ Sbjct: 10694 DNPGEKRLVAYVIAQPQANLDAASLRAELAPQLAEYMLPSAFVLLDALPLTPNRKL 10749 Score = 110 bits (264), Expect = 2e-23 Identities = 67/177 (37%), Positives = 97/177 (54%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200 PIG I + +Y+LD V G GE+ V G +ARGY+ + RFI NP NT P Sbjct: 4094 PIGRRIPDLQLYVLDARGEPVPVGVVGELYVGGAGVARGYLNREALTAERFIDNPFNTAP 4153 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LYRTGD G L G + Y GR D QVKIRG R++L E++ + V + +VL Sbjct: 4154 G-ARLYRTGDLGRWLADGSLEYLGRNDEQVKIRGFRIELGEIEAQLVACDGVQDAMVLVR 4212 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E + ++A+V A + A ++ +L SL +YM+P + +E P+ NGK+ Sbjct: 4213 EDEPGDKRLVAYVIGTAGAELDATHLREQLRLSLAEYMLPSAFVSLEAFPLTANGKL 4269 Score = 107 bits (257), Expect = 2e-22 Identities = 63/177 (35%), Positives = 98/177 (55%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200 PIGV I + +Y+LD V G GE+ V G +ARGY+ + RF+ NP + P Sbjct: 5181 PIGVRIPDLQLYVLDARREPVPVGVVGELYVGGAGVARGYLNREALTAERFLANPFSKEP 5240 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LYRTGD G + G + Y GR D QVKIRG R++L E+ ++ V +VL Sbjct: 5241 Q-ARLYRTGDLGRWMADGSLDYLGRNDDQVKIRGFRIELGEIQAVLAACNTVREALVLVR 5299 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+V P + A ++ A+L SL D+M+P + +++ P+ NGK+ Sbjct: 5300 EDQPGDKRLVAYVIAAPGHEIVAADLRAQLLLSLADHMVPSAFVALDSFPLTANGKL 5356 Score = 107 bits (257), Expect = 2e-22 Identities = 64/177 (36%), Positives = 96/177 (54%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+ N YLLDE + V G GE+ + G +ARGY+ D RF+ +P + +P Sbjct: 7346 IGKPVGNTQFYLLDEQQQPVPLGVSGEIYIGGAGVARGYLNRDDLTAERFLKDPFSQNPA 7405 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD G L G I Y GR D QVKIRG R++L E+D ++ P V VV Sbjct: 7406 -ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTARE 7464 Query: 381 VESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A+ T++ A + ++ L L YMIP + ++ +P+ NGK+ Sbjct: 7465 DVPGDKRLVAYYTLSAGHASVDIDSLRGWLQEQLPAYMIPVAYVLLDALPLTPNGKL 7521 Score = 107 bits (257), Expect = 2e-22 Identities = 63/178 (35%), Positives = 102/178 (57%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200 PIG I + +Y+LD V G GE+ V G +ARGY+ + RF+ NP + H Sbjct: 8433 PIGRRIPDLQLYVLDARGEPVPVGVVGELYVGGAGVARGYLNREALTAERFLDNPFS-HT 8491 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A++YRTGD G L G + Y GR D QVKIRG R++L E++ ++ P V + VVLC Sbjct: 8492 ADARMYRTGDLGRWLADGSLEYLGRNDEQVKIRGFRIELGEIEARLAEYPDVRDAVVLCR 8551 Query: 378 GVESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+VT PE+ + +++ L +L ++M+P ++++ +P+ NGK+ Sbjct: 8552 EDVPGDKRLVAYVTAQQPESLLDIESLREHLQGALPEHMVPAAYVQLDELPLTANGKL 8609 Score = 107 bits (256), Expect = 2e-22 Identities = 63/177 (35%), Positives = 95/177 (53%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+ N YLLDE + V G GE+ + G +ARGY+ D RF+ +P + P Sbjct: 9506 IGKPVGNTQFYLLDEQQQPVPLGVAGEIYIGGAGVARGYLNRDDLTAERFVKDPFSPQPA 9565 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD G L G I Y GR D QVKIRG R++L E+D ++ P + VV Sbjct: 9566 -ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAIHEAVVAARE 9624 Query: 381 VESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A+ T++ A + ++ L L YMIP + ++ +P+ NGK+ Sbjct: 9625 DVPGDKRLVAYYTLSAGHASVDIDSLRGWLQEQLPAYMIPVAYVLLDALPLTPNGKL 9681 Score = 106 bits (255), Expect = 3e-22 Identities = 58/176 (32%), Positives = 100/176 (56%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTHPN 203 IG P++N +YLLD + + V G GE+ + G +ARGY+ ++ + RF+ +P + P Sbjct: 11643 IGKPMANTRIYLLDAHQQPVPYGVAGEIFIGGDGVARGYLNLEEVNAERFLADPFSNSPE 11702 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++Y+TGD + G I Y GR D QVK+RG R++L E++ + V VV+ Sbjct: 11703 -ARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCTGVKEAVVIARE 11761 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V P+A + A ++ AEL L +YM+P + ++ +P+ N K+ Sbjct: 11762 DTPGDKRLVAYVVGQPQASLDAASLHAELAPQLAEYMLPSAFVILDALPLTPNRKL 11817 Score = 103 bits (248), Expect = 2e-21 Identities = 62/177 (35%), Positives = 96/177 (54%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+ N YLLDE + V G GE+ + G +ARGY+ + RF+ +P + P Sbjct: 3006 IGKPVGNTQFYLLDEQQQPVPLGVAGEIYIGGAGVARGYLNRDELTAERFLTDPFSQQPA 3065 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD G L G I Y GR D QVKIRG R++L E+D ++ P V VV Sbjct: 3066 -ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTARE 3124 Query: 381 VESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ T++ A + + ++ L L +MIP + ++ +P+ NGK+ Sbjct: 3125 DIPGDKRLVAYYTLSAGHASVDSDSLRGWLQEQLPAHMIPAAYVLLDAMPLTPNGKL 3181 Score = 103 bits (248), Expect = 2e-21 Identities = 62/180 (34%), Positives = 101/180 (56%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PI+N +++LD + G GE+ + G +ARGY+ D RFI +P ++ Sbjct: 6268 SVPIGRPIANIQMHVLDALGQLQPLGVAGELHIGGIGVARGYLNQPDLSAERFIADPFSS 6327 Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LY+TGD G L G + Y GR D QVKIRG R+++ E++ A++ P V VV Sbjct: 6328 DPQ-ARLYKTGDVGRWLANGALEYLGRNDFQVKIRGLRIEIGEIEAALAKHPAVHEAVVT 6386 Query: 372 CYGVESSNPEILAFVTINPE-ARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ T + E + + + L L +YM+P + + +E +P+ NGK+ Sbjct: 6387 AREDIPGDKRLVAYYTQSAEHTAVDIETLRGHLQQQLPEYMVPAIYVLLEAMPLTSNGKL 6446 Score = 98.3 bits (234), Expect = 1e-19 Identities = 62/181 (34%), Positives = 99/181 (54%), Gaps = 5/181 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 L++PIG P +N +YLLD V G GE+ + G +A GY+ + RF +P + Sbjct: 12692 LSLPIGKPNANVRIYLLDVCGEPVPMGSVGEIYIGGVGVALGYLNRPELSAERFSDDPFS 12751 Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 A+LYRTGD L G + Y R D QVK+RG RV+L EV+ ++ V N VV Sbjct: 12752 QQAG-ARLYRTGDLARWLPDGNLEYLARNDGQVKVRGFRVELGEVESSLHGCDGVRNSVV 12810 Query: 369 LCYGVESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542 + + ++A+ T++ + + + A+L++ L +YM+P V I + +P+ +NGK Sbjct: 12811 VAREDSPGDTRLVAYYTVHADVEAPEPEALRAQLSAGLPEYMVPSVFICLPDLPLTLNGK 12870 Query: 543 V 545 V Sbjct: 12871 V 12871 >UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2; Cystobacterineae|Rep: Non-ribosomal peptide synthase - Stigmatella aurantiaca DW4/3-1 Length = 1443 Score = 116 bits (278), Expect = 5e-25 Identities = 71/185 (38%), Positives = 104/185 (56%), Gaps = 11/185 (5%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI N +Y+LD + + V G PGE+ + G LARGY+R D RFI NP + Sbjct: 847 IPIGRPIDNTQLYILDRHRQPVPIGVPGELHIGGTGLARGYLRRPDLTAERFIPNPFQSE 906 Query: 198 PNFA---KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 + + +LYRTGD L G I + GR DSQ+KIRGHRV+ E++ A++ P V Sbjct: 907 TSGSGGDRLYRTGDLARYLPDGRIEFLGRVDSQLKIRGHRVEAGEIEAALARHPRVVQAA 966 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAE----LTSSLTDYMIPQVIEI-ETVPVL 530 V+ V +S P ++A+V A A ++ E L + DYMIP E+ + +P+ Sbjct: 967 VVLRHVPNSPPRLVAYVQAKALAEGDAAVLKEEFRKFLRGQIPDYMIPGAFEVLDELPLT 1026 Query: 531 VNGKV 545 +GK+ Sbjct: 1027 PSGKI 1031 >UniRef50_UPI000038CB2F Cluster: COG1020: Non-ribosomal peptide synthetase modules and related proteins; n=1; Nostoc punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide synthetase modules and related proteins - Nostoc punctiforme PCC 73102 Length = 918 Score = 115 bits (277), Expect = 6e-25 Identities = 62/177 (35%), Positives = 104/177 (58%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNTHP 200 PIG PI+N +++LD+N++ V GE GE+ + G LARGY+ + +FI NP ++ P Sbjct: 358 PIGRPITNAEIHILDDNLQPVPAGESGELHIGGIGLARGYLNRPELTIDKFIFNPFSSEP 417 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LY+TGD L G I + GR D QVKIRG R++L E++ + P + +V+ Sbjct: 418 G-ARLYKTGDLARYLSDGNIEFLGRIDDQVKIRGFRIELGEIEAILGQHPALTQTLVIAR 476 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + +++A++ + E S + L S L +YM+P + ++T+P+ NGK+ Sbjct: 477 DDVNGDKQLVAYIVASAEQIPSRVELRRFLQSQLPEYMVPAYFVFLDTLPLNPNGKI 533 >UniRef50_Q93H59 Cluster: Non-ribosimal peptide synthetase; n=1; Streptomyces avermitilis|Rep: Non-ribosimal peptide synthetase - Streptomyces avermitilis Length = 1709 Score = 115 bits (277), Expect = 6e-25 Identities = 68/178 (38%), Positives = 100/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG P+ N VY+LD ++ V G GE+ V G +ARGY D RF+ +P+ T Sbjct: 1406 LPIGRPLPNMRVYVLDPALQPVPVGVAGELYVGGTGVARGYANRPDLTADRFLPDPYGTG 1465 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YRTGD L G + + GR D QVKIRG+RV+L E+ ++ P V + VV Sbjct: 1466 PG-ARMYRTGDLVRHLPDGNVAFLGRVDDQVKIRGYRVELGEIQAVLTAHPAVRDAVVTV 1524 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545 + E+ P + A V + +A ++ A + L +YMIP ++T+PV NGKV Sbjct: 1525 HRPENGEPTLAAHV-VPADAAAPLPDLAAHCAARLPEYMIPATFTALDTIPVNANGKV 1581 Score = 94.3 bits (224), Expect = 2e-18 Identities = 61/178 (34%), Positives = 88/178 (49%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P+ V +L N V G PGE+ G +ARGY D RF+ +P+ T Sbjct: 317 VPIGRPLPGMRVLVLGPNGVPVPVGVPGELYAGGVGVARGYAGRPDLTADRFVPDPYATE 376 Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LYRTGD + Y GR D QVK+ G R++ EV+ A++ P V VV Sbjct: 377 PG-ARLYRTGDQVRWRSDRTLEYLGRLDHQVKVNGVRIEPAEVEAALAAHPAVTGAVVTP 435 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 Y + + A++T++ EA + L L D +P + ++ P+ NGKV Sbjct: 436 YEADGGGKRLAAYLTVSGEA--DPAGLRGFLAERLPDSHVPSFLHTLDAFPLTANGKV 491 >UniRef50_Q7N7D0 Cluster: Complete genome; segment 5/17; n=1; Photorhabdus luminescens subsp. laumondii|Rep: Complete genome; segment 5/17 - Photorhabdus luminescens subsp. laumondii Length = 1060 Score = 115 bits (277), Expect = 6e-25 Identities = 73/184 (39%), Positives = 109/184 (59%), Gaps = 11/184 (5%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200 P+G PI N +YLLDE +R VR GE GE+ + G ++ARGY+ G RF+ +P +T P Sbjct: 324 PLGKPIVNAEMYLLDEMLRPVRPGERGEIYIGGQSVARGYLYQPGLTSLRFLPDPFSTQP 383 Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN-CVVLC 374 A+++ TGD G+L G+I + GR D QVK+RGHRV+L EV+HA+ + V CVVL Sbjct: 384 G-ARMFATGDEGVLSNDGLIEFVGRLDDQVKVRGHRVELAEVEHAIKSCQDVSAVCVVLN 442 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAE------LTSSLTDYMIP-QVIEIETVPVLV 533 + +++A T + + + KN + E + + L YM P Q I+ E +P+ Sbjct: 443 IDSDRHVEQLVAHYTTHID-HTTHKNTDVEQAIITRVQTLLPSYMWPSQFIQHEQLPLTS 501 Query: 534 NGKV 545 +GKV Sbjct: 502 SGKV 505 >UniRef50_Q3M5N4 Cluster: Amino acid adenylation; n=1; Anabaena variabilis ATCC 29413|Rep: Amino acid adenylation - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 1345 Score = 115 bits (277), Expect = 6e-25 Identities = 64/176 (36%), Positives = 102/176 (57%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+N +YLLD+ + V G PGE+ + G +ARGY+ + RFI NP + PN Sbjct: 786 IGRPIANTQLYLLDDKQKLVPIGVPGELYIGGAGVARGYLNRPELTQQRFIPNPFSDEPN 845 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++LY+TGD L G I Y GR D QVKIRG R++L+E++ ++ P V+ V+ Sbjct: 846 -SRLYKTGDLARYLPDGNIEYLGRIDHQVKIRGFRIELEEIESLLAQHPLVNAVTVIARE 904 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++ ++ +A S++ + L S L +YMIP + +E +P+ +GKV Sbjct: 905 DQPGDKRLVGYIVPKEQAPTSSE-LRQFLQSKLPEYMIPSAFVMLEVIPLTTHGKV 959 >UniRef50_Q93N89 Cluster: Peptide synthetase; n=1; Streptomyces lavendulae|Rep: Peptide synthetase - Streptomyces lavendulae Length = 2116 Score = 115 bits (277), Expect = 6e-25 Identities = 65/179 (36%), Positives = 106/179 (59%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +PIG P++N ++++LD+++R V G GE+ +AG LARGY++ G RF+ P Sbjct: 298 LPIGHPLTNRHIHVLDDSLRRVAPGVTGELYIAGAGLARGYLKRAGLSAERFVACP---F 354 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + ++YRTGD D G + +AGRAD+QVKIRG RV+L EV+ A++ P V VV+ Sbjct: 355 ADGERMYRTGDLARWTDDGELAFAGRADAQVKIRGFRVELGEVEAALAAQPAVAQAVVVA 414 Query: 375 YGVESSNPEILAFVTINPEARMSAKNI-EAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ ++ P+ + ++ A L +L DYM+P + ++ +P+ VNGKV Sbjct: 415 REDRPGEKRLVGYLV--PDGHQADSDVLRARLAQTLPDYMVPAAFVVLDALPLTVNGKV 471 Score = 90.2 bits (214), Expect = 3e-17 Identities = 59/176 (33%), Positives = 93/176 (52%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+ V++LD +R V G GE+ V G +ARGY+ HRFI +P Sbjct: 1350 IGGPIARAGVHVLDGFLRPVPPGVTGELYVTGTGVARGYLNRPTLTAHRFIADPRTRG-- 1407 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++YRTGD G +++ GRAD QVK+RGHR++L EV+ A++ P V+ V + Sbjct: 1408 -GRMYRTGDLVRHTHGGELVFVGRADEQVKLRGHRIELGEVEAALADHPDVEQAVAAIH- 1465 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++ +V + A + L DYM+P V+ ++ +P+ NGK+ Sbjct: 1466 ----DARLIGYVVPADGRVPDPSALRAHASRMLPDYMLPAAVVVLDELPLTPNGKL 1517 >UniRef50_Q4C3C3 Cluster: Non-ribosomal peptide synthase:Amino acid adenylation; n=1; Crocosphaera watsonii WH 8501|Rep: Non-ribosomal peptide synthase:Amino acid adenylation - Crocosphaera watsonii Length = 1518 Score = 115 bits (277), Expect = 6e-25 Identities = 67/179 (37%), Positives = 101/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVPIG P+ N +YLLDE ++ V PGE+ + G NL+RGY + RFI NP + Sbjct: 772 TVPIGRPLDNTQIYLLDEYLQPVPLLTPGEIYIGGANLSRGYYNRPELTEERFIINPFD- 830 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LY+TGD G L G I + GR+D QVKIRG R++L E++ +S P V VV Sbjct: 831 --QSTRLYKTGDVGRYLPDGSIEFLGRSDRQVKIRGFRIELGEIEAVLSQHPSVKQAVVT 888 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E N ++A+V + + +++ + L YM+P + + ++T+PV NGK+ Sbjct: 889 VPKDEKGNQRLVAYVVLGSH---NTDHLQDFMRIRLPQYMVPHRFVTLKTIPVTANGKI 944 >UniRef50_Q1D6A0 Cluster: Non-ribosomal peptide synthetase; n=7; Bacteria|Rep: Non-ribosomal peptide synthetase - Myxococcus xanthus (strain DK 1622) Length = 11939 Score = 115 bits (277), Expect = 6e-25 Identities = 64/185 (34%), Positives = 103/185 (55%), Gaps = 4/185 (2%) Frame = +3 Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFI 176 Q + +VP+G PI N VY+LD +R V G PGE+C+ G + RGY+ D RF+ Sbjct: 5041 QGRVSASVPLGRPIPNARVYVLDAYLRPVPVGVPGELCIGGRTVGRGYLGRVDLTAERFV 5100 Query: 177 HNPHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353 + + P A++YRTGD +L G + + GR D Q+K+RG+RV++ EV+ A+ P V Sbjct: 5101 PDAYAEDPG-ARMYRTGDRARLLADGRVEFLGRTDDQLKVRGYRVEMGEVEAALERHPSV 5159 Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVL 530 VV+ + + ++ + P + + L +L DYM+PQ ++ +E +P+ Sbjct: 5160 RESVVVAHESGTDGKRLVGYAVPKPGHTLEVDALRDFLGQTLPDYMVPQALVVLEALPLT 5219 Query: 531 VNGKV 545 NGKV Sbjct: 5220 PNGKV 5224 Score = 112 bits (270), Expect = 4e-24 Identities = 66/179 (36%), Positives = 100/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +V IG P+ N VY+LD MR V G PGE+ V G LA GYV + RF+ NP+ Sbjct: 10346 SVSIGRPVKNTVVYVLDAGMRPVPVGVPGELYVGGDGLAMGYVGRPELTAERFVPNPYG- 10404 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + +LYRTGD L G + + GRAD+QVK+RG+R++L +V+ A++ V VV+ Sbjct: 10405 --DGERLYRTGDVVRWLRNGTLEFLGRADTQVKVRGYRIELGDVEAALAQHSGVSEAVVV 10462 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+VT A + A + + + L +YM+P + +E +P+ NGKV Sbjct: 10463 AREDGGEGKRLVAYVTAQEGATLDAGALRSHMKQRLPEYMVPSAYVVLEALPLTPNGKV 10521 Score = 111 bits (266), Expect = 1e-23 Identities = 65/179 (36%), Positives = 101/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +V IG P+ N Y+LD MR V G PGE+ V G LA GYV + RF+ NP+ Sbjct: 1866 SVSIGRPVKNTVAYVLDGVMRPVPVGVPGELYVGGDGLAVGYVGRPELTAERFVPNPYGE 1925 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V+ VV+ Sbjct: 1926 GE---RLYRTGDMVRWLGNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHGGVNEAVVV 1982 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+VT A +++ + + + L +YM+P + +E++P+ NGKV Sbjct: 1983 AREDGGEGKRLVAYVTAQEGAELASSALRSHMKQRLPEYMVPSAYVVLESLPLTPNGKV 2041 Score = 109 bits (263), Expect = 3e-23 Identities = 64/179 (35%), Positives = 98/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +V IG P+ N VY+LD MR V G PGE+ V G LA GYV + RF+ NP+ Sbjct: 7167 SVSIGRPVKNTVVYVLDAGMRPVPVGVPGELYVGGDGLAMGYVGRPELTAERFVPNPYGE 7226 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V+ V + Sbjct: 7227 GE---RLYRTGDVVRWLGNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHGGVNEAVAV 7283 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+VT + + + + + L +YM+P + +E +P+ NGKV Sbjct: 7284 TREDGGEGKRLVAYVTARTGTSLESSALRSHMKQRLPEYMVPSAYVVLEALPLTPNGKV 7342 Score = 109 bits (263), Expect = 3e-23 Identities = 64/179 (35%), Positives = 98/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +V IG P+ N Y+LD MR V G PGE+ V G LA GYV + RF+ NP+ Sbjct: 9287 SVSIGRPVKNTVAYVLDMGMRPVPVGVPGELYVGGDGLAVGYVGRPELTAERFVPNPYGE 9346 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V VV+ Sbjct: 9347 GE---RLYRTGDVVRWLSNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHSGVSEAVVV 9403 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+VT + + + + + L +YM+P + +E++P+ NGKV Sbjct: 9404 AREDGGEGKRLVAYVTARTGTSLESSALRSHMKQRLPEYMVPSAYVVLESLPLTPNGKV 9462 Score = 107 bits (256), Expect = 2e-22 Identities = 64/180 (35%), Positives = 98/180 (54%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 ++V IG P+ N Y+LD MR V G PGE+ V G LA GYV + RF+ +P Sbjct: 3983 VSVSIGRPVKNTVAYVLDAGMRPVPVGVPGELYVGGDGLAVGYVGRPELTAERFVPSPFG 4042 Query: 192 THPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 +LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V+ VV Sbjct: 4043 EGE---RLYRTGDVVRWLGNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHGGVNEAVV 4099 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+VT A + + + + L +YM+P + +E +P+ NGKV Sbjct: 4100 VAREDGGEGKRLVAYVTAQEGASLDTGALRSHMKQRLPEYMVPSAYVVLEALPLTPNGKV 4159 Score = 106 bits (255), Expect = 3e-22 Identities = 64/179 (35%), Positives = 98/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +V IG P+ N Y+LD MR V G PGE+ V G LA GYV + RF+ +P Sbjct: 6107 SVSIGRPVKNTVAYVLDMGMRPVPVGVPGELYVGGDGLAVGYVGRPELTAERFVPSPFGE 6166 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A+LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V+ V + Sbjct: 6167 G---ARLYRTGDVVRWLGNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHGGVNEAVAV 6223 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 S ++A+VT + + + + L +YM+P + +E++P+ NGKV Sbjct: 6224 TREDGSEGKRLVAYVTAQEGVSLETGALRSHMKQRLPEYMVPSAYVVLESLPLTPNGKV 6282 Score = 105 bits (251), Expect = 9e-22 Identities = 64/180 (35%), Positives = 98/180 (54%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHN 191 ++V IG P+ N Y+LD MR V G PGE+ V G LA GYV RF+ +P Sbjct: 8227 VSVSIGRPVKNTVAYVLDAGMRPVPVGVPGELYVGGDGLAVGYVGRPALTAERFVPSPFG 8286 Query: 192 THPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 +LYRTGD L G + + GRAD+QVK+RG+R++L EV+ A++ V+ VV Sbjct: 8287 EGE---RLYRTGDVVRWLRNGTLEFLGRADTQVKVRGYRIELGEVEAALAQHGGVNEAVV 8343 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+VT A + + + L +YM+P + +E++P+ NGKV Sbjct: 8344 VAREDGNEGKRLVAYVTAQEGASLDTGALRNHVKQRLPEYMVPSAYVVLESLPLTPNGKV 8403 Score = 102 bits (244), Expect = 6e-21 Identities = 65/178 (36%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V IG P++N +Y+LD + V G GE+ V G +ARGY+ + RF+ P Sbjct: 809 VAIGRPLTNVRIYVLDGELEPVPAGVVGELYVGGEGVARGYLGRPELTAERFVPAPQG-- 866 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + A+LYRTGD + GV+ Y GR DSQVK+RGHR++ EV+ A+ P V +V+ Sbjct: 867 -DGARLYRTGDKARWRRDGVLEYLGRGDSQVKVRGHRIEPGEVESALLGQPGVREVLVVV 925 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+V + + A L S L +M+PQ V+ +E +P+L NGKV Sbjct: 926 REDAPGDKRLVAYVVPRDGRLLEGGEVRAGLESRLPRFMVPQAVVVLERLPLLPNGKV 983 Score = 99.5 bits (237), Expect = 4e-20 Identities = 66/178 (37%), Positives = 96/178 (53%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI+N Y+LD + V G PGE+ V G LARGYV D RF+ + P Sbjct: 2926 PIGRPIANTQAYVLDAQGQPVPVGVPGELFVGGDGLARGYVGRPDLTAERFVPDALGRMP 2985 Query: 201 NFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LYRTGD G + + GR D+QVK+RGHRV+ EV+ ++ P V VV+ Sbjct: 2986 G-ARLYRTGDQVRWRSGGSLEFLGRVDTQVKVRGHRVEPGEVEVVLAEHPAVHVAVVVSR 3044 Query: 378 GVESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 S+ ++A+V + + A + A L L M+P + +E++P+L +GKV Sbjct: 3045 KDASNETRLVAYVVPGDASGAVDATALRAFLAERLPSAMVPSWFVVLESLPLLPSGKV 3102 Score = 96.3 bits (229), Expect = 4e-19 Identities = 59/176 (33%), Positives = 92/176 (52%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 +G PI Y+LD + V +G GE+ + G LARGYV + RF+ + + P Sbjct: 11403 VGRPIEGTRAYVLDALGQPVPQGVAGELYLGGAGLARGYVDRPELTAERFVPDAFSPQPG 11462 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LYRTGD L GV+ Y GR D QVK+RG R++L E++ + P V VV+ Sbjct: 11463 -ARLYRTGDSARWLPDGVLQYLGRIDQQVKVRGFRIELGEIEAVLRRHPDVREAVVVVRD 11521 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 S ++A++ + A + + L D+M+P V+ + ++P+ NGKV Sbjct: 11522 DGSEGRRLVAYIVPQSDRVPDATALRRFVKEGLPDFMVPSVVMVLASLPLTPNGKV 11577 >UniRef50_Q0SKF6 Cluster: Non-ribosomal peptide synthetase; n=2; Nocardiaceae|Rep: Non-ribosomal peptide synthetase - Rhodococcus sp. (strain RHA1) Length = 10372 Score = 115 bits (277), Expect = 6e-25 Identities = 67/180 (37%), Positives = 104/180 (57%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 +TVPIG P+ N V++LD + V G GE+ +AG LARGY+ D RF+ NPH Sbjct: 9807 VTVPIGRPVWNTQVHVLDSRLHPVPNGVAGELYLAGDQLARGYLNRPDLSADRFVANPHV 9866 Query: 192 THPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 ++YRTGD GV+ Y GR D QVK+RG R++L E++ A+ P V VV Sbjct: 9867 AG---GRMYRTGDLVRRRADGVLEYVGRTDFQVKLRGQRIELGEIEAALEAHPDVSQAVV 9923 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + + ++A++ + P A ++ A L++ + YMIP QV+ ++T+P+ NGK+ Sbjct: 9924 VVHRDDRGEEALVAYL-VGPRA-ADWSDVRAHLSARVPSYMIPAQVVHLDTLPLSANGKL 9981 Score = 104 bits (249), Expect = 2e-21 Identities = 61/178 (34%), Positives = 91/178 (51%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIGVP N Y+LD + V G PGE+ + G LARGY+ D RF+ NP Sbjct: 4484 VPIGVPEWNTQAYVLDSRLHPVPVGVPGELYLGGAQLARGYLGRVDLTSDRFVANPFGRT 4543 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G ++Y GR D QVK RG R++L E++ + + P V VV Sbjct: 4544 GE--RMYRTGDLVRWTSSGALVYIGRTDFQVKFRGQRIELGEIETVLRSHPAVTGAVVSV 4601 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 Y + ++A+V P + + + + SL YM+P I + + P+ +GK+ Sbjct: 4602 YSDTTVGDHLVAYVVGTP-GELDVAELRRQASESLPSYMVPSAITVLDEFPLNTSGKL 4658 Score = 102 bits (244), Expect = 6e-21 Identities = 63/179 (35%), Positives = 93/179 (51%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVPIGVP N VY+LD + V G GE+ +AG LARGY+ D RF+ NP Sbjct: 1872 TVPIGVPEWNTQVYVLDSRLHPVPPGVAGELYLAGEQLARGYLGRVDLTSDRFVANPFT- 1930 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD G + Y GR D QVK RG R++L E++ + P V + VL Sbjct: 1931 -PGL-RMYRTGDLVRWTSAGALEYIGRTDFQVKFRGQRIELGEIEFVLRAQPSVTSAAVL 1988 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + ++A+V P + + +SL YMIP ++ ++ P+ +GK+ Sbjct: 1989 VHSDPGTGDRLVAYVVPEPGHDLDTTRLRECAAASLPAYMIPAALMVVDEFPLNTSGKL 2047 Score = 99.1 bits (236), Expect = 6e-20 Identities = 62/182 (34%), Positives = 102/182 (56%), Gaps = 7/182 (3%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVPIG P N V++LD + V G GE+ +AG LARGYV D RF+ NP Sbjct: 8743 TVPIGGPEWNTQVFVLDARLNPVPVGVAGELYLAGEQLARGYVARADLTAERFVANPFGA 8802 Query: 195 HPNFAKLYRTGD---FGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 + ++LYRTGD + + D +GV+ Y R+D QVK+RG R++L E++ A+ + V Sbjct: 8803 --SGSRLYRTGDVVRWHVRDSRGVLEYLERSDFQVKVRGFRIELGEIESALVSSAGVGQA 8860 Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539 VV+ + + ++ +V A + + AE+ +++ YM+P ++ + +P+ NG Sbjct: 8861 VVVAHQHPHTGTTLIGYVVPEDGATVDFAAVLAEVGAAVPSYMVPAALVVLAQLPLTSNG 8920 Query: 540 KV 545 K+ Sbjct: 8921 KL 8922 Score = 92.3 bits (219), Expect = 7e-18 Identities = 55/178 (30%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V +G P+ N Y+LD+ + G GE+ +AG ++RGY D RF+ NP + Sbjct: 2935 VTVGTPVWNTRAYVLDQRLHPSPAGVTGELYLAGTQVSRGYAGRPDLTAERFVANPFDA- 2993 Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD +G + Y GR D QVK+RG R++L E++ + + V VV Sbjct: 2994 PG-TRMYRTGDRLRWTGRGELEYLGRNDFQVKLRGLRIELGEIEAVLESADSVAQAVVTV 3052 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 Y +S +++A++ R+ + + A S L +YM+P + ++ P+ +GK+ Sbjct: 3053 YSGAASE-QLVAYLVARAGTRVDIEALTAYAASRLPEYMVPDGFVTLDAFPLNASGKL 3109 Score = 87.4 bits (207), Expect = 2e-16 Identities = 58/182 (31%), Positives = 97/182 (53%), Gaps = 8/182 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V +G P + +LD +R V G GE+ V G +LARGYVR G RF+ +P T Sbjct: 806 VTVGSPTVGVDLVVLDHRLRPVPAGVRGELYVLGSSLARGYVRRAGLTAERFVASPFGTG 865 Query: 198 PNFAKLYRTGD---FGILDKG--VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 ++YRTGD + G V+ + GR+D QVKIRG R++L E+D A++ P V+ Sbjct: 866 ---GRMYRTGDVVRWVTAPDGPPVLEFLGRSDFQVKIRGFRIELGEIDAALTAHPVVEFA 922 Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539 + Y S + ++++V P + + + + L YM+P ++ ++++P+ G Sbjct: 923 YTVGYDDGSGSSRLVSYVLPVPATDVETRVLSEFVGERLPGYMVPSSIMMLDSLPLTPAG 982 Query: 540 KV 545 K+ Sbjct: 983 KL 984 Score = 85.4 bits (202), Expect = 8e-16 Identities = 56/180 (31%), Positives = 89/180 (49%), Gaps = 8/180 (4%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG P+ ++LD + V G PGE+ ++G LARGY + G RF+ NPH P Sbjct: 5542 IGAPVRGVEAFVLDARLHPVSPGVPGELYISGPALARGYHQRLGLTAERFVANPHGA-PG 5600 Query: 204 FAKLYRTGDF-----GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 ++YRTGD VI Y GR+D QVKIRG RV+L E+D V Sbjct: 5601 -RRMYRTGDLVRWVESRTGTYVIEYVGRSDFQVKIRGFRVELGEIDSVFRAHSAVGFAAT 5659 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + ES ++ +V + ++ A + L +M+P ++ ++++P+ GK+ Sbjct: 5660 IAHDTESGVTALVTYVCAASGNDVDVDDLTAFVGGVLPAHMVPGSIMVLDSIPLTPAGKL 5719 Score = 81.0 bits (191), Expect = 2e-14 Identities = 55/178 (30%), Positives = 90/178 (50%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V IG P +LD +R V G PGE+ V G +LARGY+ G RF+ +P+ Sbjct: 7680 VTIGGPSRGVRALVLDGRLRPVPVGVPGELYVGGPSLARGYLGRPGLTAERFVADPYGEP 7739 Query: 198 PNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + +YRTGD + +L + GR D QVKIRG R++L E+D A++ P ++ + Sbjct: 7740 GDL--MYRTGDLVRWRENRVLDFVGRTDHQVKIRGFRIELGEIDAALTAHPQIEYATTIG 7797 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 Y + ++A+V + + + +L YM+P V ++ +P+ GK+ Sbjct: 7798 YEHPNGETSLVAYVLPFTGEDVDRVEVANFVGRTLPAYMVPASVTLLDALPLTPAGKL 7855 Score = 77.4 bits (182), Expect = 2e-13 Identities = 60/193 (31%), Positives = 93/193 (48%), Gaps = 19/193 (9%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 + IG P+ +LD +R V G GE+ + G LARGY HRF+ +P Sbjct: 6602 ITIGGPLPGVAAVVLDSRLRPVPVGVVGELYLLGPALARGYHERAALTAHRFVASPFEAA 6661 Query: 198 PNFAKLYRTGDF-----------GILDKGV-----ILYAGRADSQVKIRGHRVDLQEVDH 329 A++YRTGD G + G I Y GR+D QVK+RG R++L E+D Sbjct: 6662 G--ARMYRTGDIVRWRAVHSGVTGSMTDGTFPGHAIEYLGRSDHQVKVRGLRIELGEIDA 6719 Query: 330 AVSTIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VI 506 A++ P V+ L Y + + + V + A + A L +L YM+P ++ Sbjct: 6720 ALNAHPDVEFAATLGY-ESPAETRLASHVLVGAGADRDPAALLAFLRQALPGYMVPSALV 6778 Query: 507 EIETVPVLVNGKV 545 ++T+P+ NGK+ Sbjct: 6779 FLDTIPLTPNGKL 6791 >UniRef50_A7BXM0 Cluster: Non-ribosomal peptide synthetase; n=2; Beggiatoa|Rep: Non-ribosomal peptide synthetase - Beggiatoa sp. PS Length = 662 Score = 115 bits (277), Expect = 6e-25 Identities = 63/180 (35%), Positives = 101/180 (56%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PI+N +Y++D + + V G GE+ + G +ARGY+ D FI NP N Sbjct: 210 SVPIGRPIANTQIYIVDHDYQPVPIGVIGELYIGGDGVARGYLNRPDLTAETFIPNPFNQ 269 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 LY+TGD L +G I Y GR D+QV+IRG RV+L E++ ++ P V VV+ Sbjct: 270 DGKNGPLYKTGDLARYLPEGNIEYLGRIDNQVQIRGFRVELGEIEKVLTQHPAVRESVVI 329 Query: 372 CYGVESSNPEILAF-VTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 N ++A+ + + E ++ + + +L DYM+P +++ET+P+ NGK+ Sbjct: 330 VKEEPEQNQRLIAYIIPVASEDKIDISELRRFIAETLPDYMVPSFFVKMETIPLTPNGKI 389 >UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine synthetase II) [Includes: ATP- dependent proline adenylase (ProA) (Proline activase); ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)]; n=5; Paenibacillaceae|Rep: Tyrocidine synthetase 2 (Tyrocidine synthetase II) [Includes: ATP- dependent proline adenylase (ProA) (Proline activase); ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] - Brevibacillus parabrevis Length = 3587 Score = 115 bits (277), Expect = 6e-25 Identities = 64/176 (36%), Positives = 102/176 (57%), Gaps = 4/176 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PISN +Y+LDE ++ EG GE+ ++G N+ RGY+ + +F+ NP+ P Sbjct: 781 PIGKPISNTGIYILDEGLQLKPEGIVGELYISGANVGRGYLHQPELTAEKFLDNPY--QP 838 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD + L G + + GR D QVKIRGHR++L E++ + P + VV+ Sbjct: 839 G-ERMYRTGDLALWLPDGQLEFLGRIDHQVKIRGHRIELGEIESRLLNHPAIKEAVVIDR 897 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542 E+ + A+V + + +S + + A L +L +YMIP + +E +PV NGK Sbjct: 898 ADETGGKFLCAYVVL--QKALSDEEMRAYLAQALPEYMIPSFFVTLERIPVTPNGK 951 Score = 104 bits (250), Expect = 1e-21 Identities = 61/179 (34%), Positives = 96/179 (53%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+ IG PI N +Y++D+ ++ G+ GE+C++G +LARGY + +F+ NP Sbjct: 2847 TITIGKPIQNTKLYIVDDQLQLKAPGQMGELCISGLSLARGYWNRPELTAEKFVDNPF-- 2904 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P K+YRTGD L G I Y GR D QVKIRGHRV+L EV+ + V + Sbjct: 2905 VPG-TKMYRTGDLARWLPDGTIEYLGRIDHQVKIRGHRVELGEVESVLLRYDTVKEAAAI 2963 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + + A+ EA + + A + + L +YM+P I++E +P+ N K+ Sbjct: 2964 THEDDRGQAYLCAYYVAEGEA--TPAQLRAYMENELPNYMVPAFFIQLEKMPLTPNDKI 3020 Score = 101 bits (242), Expect = 1e-20 Identities = 55/178 (30%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 + IG PI+N +Y++D++ + + G GE+C+ G LARGY + + +F+ NP Sbjct: 1815 ITIGRPIANTAIYIVDQHHQLLPVGVVGEICIGGHGLARGYWKKPELTAEKFVANP--AV 1872 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++Y+TGD G L G I + GR D Q+K+RG+R+++ E++ + + +V+ Sbjct: 1873 PG-ERMYKTGDLGRWLHDGTIDFIGRVDDQIKVRGYRIEVGEIEAVLLAYDQTNEAIVVA 1931 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 Y + + + A+VT + + + A L L YM+P +I+++ P+ NGKV Sbjct: 1932 YQDDRGDSYLAAYVT--GKTAIEESELRAHLLRELPAYMVPTYLIQLDAFPLTPNGKV 1987 >UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP- dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine activase); Leucine racemase [ATP- hydrolyzing] (EC 5.1.1.-)]; n=11; cellular organisms|Rep: Linear gramicidin synthetase subunit C [Includes: ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP- dependent tryptophan/phenylalanine/tyrosine adenylase (Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine activase); Leucine racemase [ATP- hydrolyzing] (EC 5.1.1.-)] - Brevibacillus parabrevis Length = 7756 Score = 115 bits (277), Expect = 6e-25 Identities = 64/177 (36%), Positives = 101/177 (57%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PISN VY+LD++ + V G GE+ + G LA GY+ + RF+ NP + Sbjct: 781 PIGRPISNTTVYVLDKHKQPVPYGAAGELYIGGDGLALGYLNNAELTAERFVENPFDPQK 840 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++LYRTGD L G I + GR D+QVKIRG R++L EV+ A++ P V VV+ Sbjct: 841 G-SRLYRTGDLVRYLPNGTIEFIGRIDNQVKIRGFRIELGEVEAALALHPEVSETVVMAR 899 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + A+VT+ + +++A L + L +YM+P + ++ +P+ NGK+ Sbjct: 900 ENDRGEKHLTAYVTVAKDDAPEVADLQAWLKTKLPEYMVPSAYVFLDAMPLTANGKI 956 Score = 112 bits (269), Expect = 6e-24 Identities = 66/179 (36%), Positives = 102/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 + PIG P++N +Y+LD N + V G PGE+ + G LARGY + RFI +P Sbjct: 3365 SAPIGRPLANATLYVLDANQKPVPVGVPGELYIGGKGLARGYWNRPELTAERFIAHPFGA 3424 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LYRTGD L G + + GR D+QVKIRG+R++L E++ A+S P + VV+ Sbjct: 3425 KGE--RLYRTGDLVRYLPDGNLEFLGRIDTQVKIRGYRIELGEIESALSQHPAIQEAVVI 3482 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + A++ EA+ +A+ + L +L DYMIP + ++ +P+ VNGKV Sbjct: 3483 AW-----EQRLAAYMVAAGEAQPAAEELARYLKETLPDYMIPAGFVFMDAIPLTVNGKV 3536 Score = 111 bits (266), Expect = 1e-23 Identities = 64/177 (36%), Positives = 100/177 (56%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI+N VY+LD +++ V G PGE+ + G +ARGY + RFI +P Sbjct: 5946 PIGRPIANTTVYVLDAHLQPVPIGVPGELYIGGKGVARGYWNRPELTAERFIADPFGQAD 6005 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +LYRTGD L+ G + + GR D QVKIRG+R++L E+++A+ P V N VV+ Sbjct: 6006 E--RLYRTGDLVRYLENGELEFLGRIDDQVKIRGYRIELGEIENALRQHPAVQNVVVIAR 6063 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + + A++ + + L S+L +YM+P + +E +P+ VNGKV Sbjct: 6064 QEGAGDKRLAAYLVAATGQQPDEAELVRYLKSTLPEYMVPAGYVWLEKIPLTVNGKV 6120 Score = 109 bits (261), Expect = 5e-23 Identities = 65/176 (36%), Positives = 94/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI N VY+LDE + V G GE+ +AG +LARGY + D RF+ NP + Sbjct: 7007 IGRPIDNVQVYILDEQRQPVPIGVTGELYIAGSSLARGYYKRPDLTQERFVDNPFTANRG 7066 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 AK+YRTGD L G I + GR+D QV IRG RV+L E++ + P V +VL Sbjct: 7067 -AKMYRTGDLVRYLPDGQIEFIGRSDDQVSIRGFRVELGEIESVLYQHPAVKEAIVLARE 7125 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + A+V + + A ++ L L +YM+P + ++ +P+ NGKV Sbjct: 7126 DMPGVKRLAAYVVVAEDDAEQADDLRGYLKEKLPEYMVPAAFVTLKALPLTPNGKV 7181 Score = 104 bits (250), Expect = 1e-21 Identities = 61/177 (34%), Positives = 95/177 (53%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PISN VY+LD+N + V G GE+ + G LA GY+ + RF+ NP + Sbjct: 1846 PIGRPISNTTVYVLDKNRQPVPLGVAGELYIGGDGLASGYLNNPELTAERFVDNPFDPQ- 1904 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++LYRTGD L G I + GR D+QVKIRG R++L E++ A+ P V ++ Sbjct: 1905 KASRLYRTGDLVRYLPDGAIEFIGRIDNQVKIRGFRIELGEIETALLRHPAVQEAFLMVR 1964 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + A++ + + + L L +YMIP +++++ P+ NGKV Sbjct: 1965 EDAPGDKRLAAYLVFAGGQTVEPVEMRSYLKDKLPEYMIPSAFVQMDSFPLTPNGKV 2021 Score = 99.1 bits (236), Expect = 6e-20 Identities = 66/180 (36%), Positives = 99/180 (55%), Gaps = 8/180 (4%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI N VY+LDE ++ V G GE+ +AG +LARGY+ D RFI NP+ Sbjct: 4423 IGRPIDNVQVYVLDEKLQPVPIGVAGELYIAGDSLARGYLHRPDLTRERFIANPYGQKAG 4482 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++Y+TGD L G I + GRAD QV IRG RV+L E++ A+ + P V +VL Sbjct: 4483 -ARMYKTGDLVRYLPDGNIEFIGRADDQVSIRGFRVELGEIETALYSHPAVKETIVLVRE 4541 Query: 381 VESSNPEILAFVTINPEAR----MSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A++ + E + + A + + L L +YM+P + + +P+ NGKV Sbjct: 4542 DMPGMKRLVAYI-VQREGQEGQAVQAGDFRSYLKELLPEYMVPAAFVFMADLPLTPNGKV 4600 >UniRef50_Q83DF1 Cluster: Peptide synthetase, putative; n=6; Coxiella burnetii|Rep: Peptide synthetase, putative - Coxiella burnetii Length = 446 Score = 115 bits (276), Expect = 8e-25 Identities = 66/180 (36%), Positives = 102/180 (56%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVPIG + N+ +Y++DEN R V +GE GE+ + G ++A GY + + RFI NP + Sbjct: 252 TVPIGQAVRNSRLYVVDENNRPVEQGEVGELLIGGASVACGYYKAPELTRERFIKNPFSA 311 Query: 195 HPNFAKLYRTGDF--GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 + LYRTGD + DK LY GR D+QVKI G+ V+L EV++ + +++ + Sbjct: 312 EDDI--LYRTGDLVKQLPDKS-FLYLGRIDNQVKINGYLVELNEVEYCLLRQTSIEHAYI 368 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 L E + + A+V + P+A + I L+ L +MIPQ I+ +P+ NGKV Sbjct: 369 LAKKHEDGHQSLEAYVVLKPQATFNEAEIRNRLSQQLPQFMIPQHYYLIDRIPLTPNGKV 428 >UniRef50_Q70C47 Cluster: Polyketide non-ribosomal peptide synthase; n=2; Xanthomonas albilineans|Rep: Polyketide non-ribosomal peptide synthase - Xanthomonas albilineans Length = 6879 Score = 115 bits (276), Expect = 8e-25 Identities = 69/178 (38%), Positives = 103/178 (57%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG PI+N VY+LD +R V G GE+ V +ARGY G RFI +P++ Sbjct: 4087 VPIGAPIANTEVYVLDRQLRQVPIGVMGELHVHSVGMARGYWNRPGLTASRFIAHPYSEE 4146 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +LY+TGD L G + Y GR D +VK+RGHRVD ++V+ A+ P V VV Sbjct: 4147 PG-TRLYKTGDMVRRLADGTLEYLGRQDFEVKVRGHRVDTRQVEAALRAQPAVAEAVVSG 4205 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + V+ + +++A+V SA ++ +L++ L YM+P V + +E +P L NGK+ Sbjct: 4206 HRVD-GDMQLVAYVVAREGQAPSAGELKQQLSAQLPTYMLPTVYQWLEQLPRLSNGKL 4262 Score = 115 bits (276), Expect = 8e-25 Identities = 69/178 (38%), Positives = 103/178 (57%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG PI+N VY+LD +R V G GE+ V +ARGY G RFI +P++ Sbjct: 6165 VPIGAPIANTEVYVLDRQLRQVPIGVMGELHVHSVGMARGYWNRPGLTASRFIAHPYSEE 6224 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +LY+TGD L G + Y GR D +VK+RGHRVD ++V+ A+ P V VV Sbjct: 6225 PG-TRLYKTGDMVRRLADGTLEYLGRQDFEVKVRGHRVDTRQVEAALRAQPAVAEAVVSG 6283 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + V+ + +++A+V SA ++ +L++ L YM+P V + +E +P L NGK+ Sbjct: 6284 HRVD-GDMQLVAYVVAREGQAPSAGELKQQLSAQLPTYMLPTVYQWLEQLPRLSNGKL 6340 Score = 43.2 bits (97), Expect = 0.004 Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 1/113 (0%) Frame = +3 Query: 90 REGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAKLYRTGDFGILDKGVILYAG 269 R E GE+ V +ARGY+ K + N H + + +RTGD G + G + G Sbjct: 446 RPDEIGEIWVKSPAIARGYLFAKPADQRQFNCSIRHTDDSGYFRTGDLGFIADGCLYVTG 505 Query: 270 RADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVESSNPE-ILAFVTIN 425 R + IRG ++ +++ + + + +E + E + A + +N Sbjct: 506 RVKEVLIIRGKNHYPAHIEASIAATASPGALMPVVFSIERQDEERVAAVIAVN 558 >UniRef50_Q2VQ13 Cluster: Nonribosomal peptide synthetase E; n=1; Brevibacillus texasporus|Rep: Nonribosomal peptide synthetase E - Brevibacillus texasporus Length = 2526 Score = 115 bits (276), Expect = 8e-25 Identities = 66/176 (37%), Positives = 101/176 (57%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P N Y+LD+ G PGE+CV G +ARGY+ + +F+++P+ PN Sbjct: 766 IGTPTVNKRAYILDQYGHIQPIGVPGELCVGGEGVARGYLHRPELTDEKFVNDPYV--PN 823 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++Y+TGD L G I + GR D QVKIRG R++L E++ ++ P V VVL Sbjct: 824 -GRMYKTGDLARWLPDGTIEFLGRMDGQVKIRGFRIELGEIEARLNQAPSVKQAVVLARS 882 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E + A++ + + ++SA + EL+ +L DYMIP I++E +PV VNGK+ Sbjct: 883 GEQKQVYLCAYLVTDNDLKVSA--LRKELSQTLPDYMIPSFFIKVEKIPVTVNGKI 936 Score = 103 bits (246), Expect = 4e-21 Identities = 62/178 (34%), Positives = 100/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 + IG P N VY+++EN + G PGE+C+AG L+RGY+ + +F++NP Sbjct: 1789 ITIGKPFPNQKVYIINENQQLQPIGVPGELCIAGAGLSRGYLNRPELTQEKFVNNPF--A 1846 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++Y+TGD L G I YAGR D QVK+RG+RV+L EV + T P + VV+ Sbjct: 1847 PG-ERMYKTGDVARWLPDGNIEYAGRMDDQVKVRGNRVELGEVTSQLLTHPSITEAVVVP 1905 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + A+ + E +++ ++ L +L ++MIP I+++ +P+ NGKV Sbjct: 1906 IVDTHGATTLCAYFIEDKEVKVN--DLRHHLAKALPEFMIPTYFIKVDHIPLTGNGKV 1961 >UniRef50_Q8L334 Cluster: Peptide synthetase; n=14; Nostocaceae|Rep: Peptide synthetase - Aphanizomenon ovalisporum Length = 1869 Score = 114 bits (275), Expect = 1e-24 Identities = 68/182 (37%), Positives = 101/182 (55%), Gaps = 8/182 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VP+G P+ N VY+LDE + V GE GE+C+ G LARGY D +FI NP T+ Sbjct: 379 VPVGRPLHNVQVYILDEAQQPVPVGEEGELCIGGIGLARGYHNLPDLTNEKFIPNPFGTN 438 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 N KLYRTGD L G I + GR D QVKIRG RV+L E++ +++ V C V+ Sbjct: 439 GNAKKLYRTGDLARYLPDGTIEHLGRIDHQVKIRGFRVELGEIESVLTSHQAVRECAVVA 498 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAEL----TSSLTDYMIP-QVIEIETVPVLVNG 539 + + + +++ ++ +S +E L + L +YMIP + I I +P+ +G Sbjct: 499 REI-AGHTQLVGYILAKDTPNLSFDKLEPILRQYSEAVLPEYMIPTRFINISNMPLTPSG 557 Query: 540 KV 545 K+ Sbjct: 558 KL 559 >UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2; Bacteria|Rep: Amino acid adenylation domain - Burkholderia cepacia (strain ATCC 53795 / AMMD) Length = 3176 Score = 114 bits (275), Expect = 1e-24 Identities = 71/179 (39%), Positives = 100/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TV IG PI+N VY+LD+ +R V G PGE+C+AG LARGY + D +F+ +P Sbjct: 562 TVLIGRPIANTRVYMLDDALRPVPLGVPGEICIAGDGLARGYHQRPDVTAAKFVEHP--- 618 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A++YRTGD G L G I GR D QVKIRGHRV+L E++ A++ V V+ Sbjct: 619 FPGEARIYRTGDIGRWLPDGQIQCYGRVDDQVKIRGHRVELGEIEAALTAHEDVVGAAVM 678 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ A+V A ++ ++ A L L DYM+P + I P+ NGK+ Sbjct: 679 LRESAHGVRKLAAYV--KGSANLNVADLRAFLAGKLPDYMVPSDIFPIAEFPLNANGKL 735 Score = 102 bits (245), Expect = 5e-21 Identities = 62/179 (34%), Positives = 103/179 (57%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N VY++D ++ V G GE+ + G + RGY + +FI +P + Sbjct: 1610 VPIGRPIANTRVYIVDAQLQPVPVGVAGELLIGGTPVGRGYHGEPELSAEKFIADPFSAD 1669 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A+LYRTGD G I + GR D Q+K+RG R++ E++ A+ P VD+CVV+ Sbjct: 1670 SQ-ARLYRTGDLARYRPDGNIEFLGRIDHQIKLRGLRIEPGEIEAALREHPSVDDCVVIA 1728 Query: 375 YGVESSNPEILAFV-TINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + ++A+V T +P+ ++ L+ L DYM+P + + +E++P+L NGK+ Sbjct: 1729 -KTDGARTFLIAYVATASPD----LADLRGYLSGKLADYMVPSKFVTLESLPLLPNGKI 1782 >UniRef50_A5N8Z4 Cluster: Predicted hybrid nonribosomal peptide synthetase/polyketide synthase; n=1; Clostridium kluyveri DSM 555|Rep: Predicted hybrid nonribosomal peptide synthetase/polyketide synthase - Clostridium kluyveri DSM 555 Length = 2001 Score = 114 bits (275), Expect = 1e-24 Identities = 60/178 (33%), Positives = 101/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 + IG PISN +Y++D+N + G GE+C+ G +ARGY+ KD +F +NP+ + Sbjct: 1531 ISIGKPISNTQIYIIDKNNKLQPIGVSGELCIGGDGVARGYLNRKDLTKEKFFNNPYKVN 1590 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 K+YRTGD G + + GR D+QVKIRG+R++L E++ ++ T + CVV+ Sbjct: 1591 ---EKIYRTGDLAKWQPDGTVEFLGRIDNQVKIRGYRIELSEIEKSLGTCKGIKECVVIS 1647 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + ++A+ + E +S + + L DYMIP + I+ +P+ NGK+ Sbjct: 1648 RENSTGDKYLIAYYVADMEIGVS--KLREHMLKELPDYMIPSYFVPIKCMPLTPNGKI 1703 >UniRef50_A3YFF7 Cluster: Amino acid adenylation; n=1; Marinomonas sp. MED121|Rep: Amino acid adenylation - Marinomonas sp. MED121 Length = 3118 Score = 114 bits (275), Expect = 1e-24 Identities = 72/191 (37%), Positives = 107/191 (56%), Gaps = 10/191 (5%) Frame = +3 Query: 3 QMHIF-LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRF 173 +MHI ++ IG PI NN +Y+LDE + V+ GE GE+ VAG N+ GY+ +F Sbjct: 1425 EMHIQEKSIHIGYPIPNNRLYVLDEAKKPVKLGEIGELYVAGANVGLGYLNNPALTQLKF 1484 Query: 174 IHNPHNTHPNFAK-LYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP 347 +P H N K +Y+TGD I D G I AGRAD Q+KI G R++ E++H + + Sbjct: 1485 TQDPFVDHQNVKKRMYQTGDLAIQRDDGAIELAGRADFQIKINGFRIEAGEIEHCILSHQ 1544 Query: 348 CVDNCVVLCYGVESSNPEILAFVTIN----PEARMSAKNIEAELTSSLTDYMIPQVI-EI 512 + +V+ ES+ I+A++ N + KNI+A L +SL YM P +I + Sbjct: 1545 GITQALVVQQQDESAGDLIIAYIIPNKASLSQTESLIKNIKARLATSLPTYMQPSLIMPL 1604 Query: 513 ETVPVLVNGKV 545 ET P+ NGK+ Sbjct: 1605 ETFPLTQNGKI 1615 Score = 94.3 bits (224), Expect = 2e-18 Identities = 57/180 (31%), Positives = 93/180 (51%), Gaps = 6/180 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNTH 197 VPIGV I + ++ EN + +GE GE+ ++G +LA GY+ + RF Sbjct: 328 VPIGVAIGQTSILIIKENNKIALKGEKGELYLSGPSLAEGYLNDAVQTEKRFTFRADLGA 387 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + Y+TGD +L D + Y GR D QVKIRGHRV++ E+DH + T P + Sbjct: 388 NSQNLWYKTGDLVVLNDNNEVDYLGRLDDQVKIRGHRVEVGEIDHYLLTHPYIKEAATFG 447 Query: 375 YGVESSNPEILAFVTINPEAR--MSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 ++ +++ +N E +S ++++ L SL YM+P I I + +P+ N K+ Sbjct: 448 VSQSLGEKDLYSYLVLNQENNNALSKQDVKEYLKHSLPSYMLPHRIFITDKMPLTANQKL 507 >UniRef50_A3INW9 Cluster: Amino acid adenylation; n=1; Cyanothece sp. CCY 0110|Rep: Amino acid adenylation - Cyanothece sp. CCY 0110 Length = 1092 Score = 114 bits (275), Expect = 1e-24 Identities = 62/179 (34%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVP+G P+ N +Y+LD ++ V G GE+ + G NL+RGY+ + RFI NP + Sbjct: 786 TVPLGTPLPNTQMYILDRYLQPVPIGVTGELYIGGDNLSRGYLNQPELTEERFIENPFDK 845 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 KLY+TGD G I + GR+D Q+KIRG R++L EV+ + P + VV Sbjct: 846 Q---TKLYKTGDLARYFPDGTIEFLGRSDRQIKIRGFRIELGEVEGTLRQHPQIQEAVVT 902 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + NP ++A++ + E + + + L L+D+MIP + ++T P+ NGK+ Sbjct: 903 SWEASPGNPRLVAYLISSEEEKPENEILNHFLAQKLSDFMIPSHFLWLDTFPLTPNGKI 961 >UniRef50_A7T272 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 705 Score = 114 bits (275), Expect = 1e-24 Identities = 63/178 (35%), Positives = 106/178 (59%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 P+G + + ++D+ M+ + G PGE+ V G LARGY+ + RFI P + Sbjct: 334 PVGKLLPGVQIVIMDKKMKPLPVGLPGEIFVGGPTLARGYLNRPELNKERFISRPASVPA 393 Query: 201 NFA-KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + +LY TGD+G +L G + GR DS VKIRG+ +++Q V+ A+ +P ++ CVVL Sbjct: 394 SVGERLYSTGDWGYMLSSGALEICGRCDSMVKIRGYSIEIQAVEAALLQLPMINACVVLA 453 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 G E ++ ++A+V PE +++ K+I A L + L YMIP + ++++PV +GK+ Sbjct: 454 LGEEGTDKYLVAYVV--PEGKVTKKDIRATLKTRLPFYMIPAHFVLLQSIPVAPSGKL 509 >UniRef50_A0UUS4 Cluster: Amino acid adenylation domain; n=1; Clostridium cellulolyticum H10|Rep: Amino acid adenylation domain - Clostridium cellulolyticum H10 Length = 2752 Score = 114 bits (274), Expect = 1e-24 Identities = 65/179 (36%), Positives = 103/179 (57%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++PIG PI N + ++D+NM+ G GE+C+ G LAR Y+ + +FI NP+ Sbjct: 2027 SIPIGKPIDNTKLLIMDKNMQLQPVGVTGELCIGGNCLAREYLNKPEMTDEKFIPNPYK- 2085 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 PN +LYRTGD + G I Y GR D QVKIRG R++L E++ ++ P V CVV+ Sbjct: 2086 -PN-ERLYRTGDLAKWRRDGNIEYLGRIDFQVKIRGLRIELGEIEKQLTAHPDVKECVVV 2143 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+V + I++ L SL DYM+P++ + +E +P+ NGK+ Sbjct: 2144 AWKKGEGDIHLVAYVVCENSMQAEQGGIQSFLEKSLPDYMVPRIYVFLEMMPLSPNGKI 2202 >UniRef50_O31782 Cluster: Polyketide synthase of type I; n=2; Bacillus subtilis|Rep: Polyketide synthase of type I - Bacillus subtilis Length = 5488 Score = 113 bits (273), Expect = 2e-24 Identities = 66/177 (37%), Positives = 101/177 (57%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200 PIG P+SN +Y++D++++ V G+PGE+C+AG LARGY + G +FI NP + Sbjct: 790 PIGKPVSNTKIYIVDQHLKPVPIGKPGELCIAGAGLARGYFKKPGLTAEKFIDNPFESG- 848 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 KLY++GD L G I Y GR DSQVKIRG RV+L ++ + P + + V+ Sbjct: 849 --TKLYKSGDSARWLPDGNIEYLGRIDSQVKIRGFRVELGAIETKLGEFPGILDQAVVVK 906 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +E + + A + K++ L SSL +YMIP I ++ +P+ +GKV Sbjct: 907 QLEGHQQLAAYYTEESGHASANPKDLRLHLKSSLPEYMIPSHFIRLDELPLSPSGKV 963 >UniRef50_A5FI48 Cluster: Amino acid adenylation domain; n=2; cellular organisms|Rep: Amino acid adenylation domain - Flavobacterium johnsoniae UW101 Length = 2894 Score = 113 bits (273), Expect = 2e-24 Identities = 68/179 (37%), Positives = 101/179 (56%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V IG P++N VY+L EN++ G GE+C++G L++GY+ + +FI NP Sbjct: 1557 VSIGKPVANTQVYILSENLKLQPVGVIGELCISGIGLSKGYLNQPELTKEKFIQNPFEPE 1616 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTI-PCVDNCVVL 371 KLY+TGD L G + Y GR D+QVKIRG+RV+L E+++ + + N VVL Sbjct: 1617 ---EKLYKTGDLARWLPDGNLEYVGRKDNQVKIRGNRVELGEIEYVIREFDSAISNAVVL 1673 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 V+ + P I+A+ T + K + L L DYMIP +E+ET+ + NGKV Sbjct: 1674 VKEVK-NEPFIIAYYTTGKS--VDKKELRKYLKDKLADYMIPAYYVELETLQLNANGKV 1729 Score = 93.1 bits (221), Expect = 4e-18 Identities = 56/181 (30%), Positives = 93/181 (51%), Gaps = 4/181 (2%) Frame = +3 Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH 188 + T+PIG ISN Y+LDE ++ V G G++ ++G +A GY+ + +FI NP Sbjct: 523 YQTIPIGKAISNTQAYILDEELQLVPMGTIGKLYLSGDGIANGYLNKPELTAAKFIENP- 581 Query: 189 NTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 K+Y TGD + G + + GR D Q+K+RG+R++L+E+++ +S+ +N Sbjct: 582 --FAEGHKMYDTGDLVKWMPDGNLAFLGRKDHQIKLRGYRIELEEIENVISSFS--ENIG 637 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGK 542 V +N E +S ++ A L L YMIP +E +P+ NGK Sbjct: 638 QAVVAVRKNNGEDFLAAYFTEIENVSKTDLRAYLEKQLPAYMIPSYFTAVEKIPLTPNGK 697 Query: 543 V 545 + Sbjct: 698 I 698 Score = 75.8 bits (178), Expect = 6e-13 Identities = 53/176 (30%), Positives = 88/176 (50%), Gaps = 2/176 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 +P+G + V+LLDEN + + GE+ L+ GY+ ++ + N Sbjct: 2606 MPLGKSVEETKVFLLDENNKPKGIYQTGEIVFKSDYLSLGYLNRQELTDKVFTTDPLTGN 2665 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++Y++GD G+ L G I + R DSQVKI G R++L E+++ + I ++ VVL Sbjct: 2666 -GRVYKSGDIGMMLPSGEIEFLQRKDSQVKINGLRIELSEIEYQLEQIEFINEAVVLLKE 2724 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ N I A+V E + I+ L L YMIP + I +E P+ GK+ Sbjct: 2725 LQ-ENSYITAYV--RSEEILDVTKIKLLLGKILPKYMIPAIYISMENFPLTRTGKI 2777 >UniRef50_A3INW8 Cluster: Peptide synthetase; n=3; Chroococcales|Rep: Peptide synthetase - Cyanothece sp. CCY 0110 Length = 1876 Score = 113 bits (273), Expect = 2e-24 Identities = 67/178 (37%), Positives = 102/178 (57%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 + IG PI+N +Y+LD +++ V G PGE+ + G LARGYV +D RFI++P N Sbjct: 796 ITIGRPINNTQIYILDNHLQPVPIGIPGELYIGGDGLARGYVNRRDLTEERFINSPFN-- 853 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P K+Y+TGD L G + Y GR+D QVKIRG R++L E++ ++ V N VV+ Sbjct: 854 PG-KKIYKTGDIAKYLPNGKVEYIGRSDYQVKIRGFRIELGEIESQLNQHLGVKNAVVVA 912 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 S ++A+ E+ ++ +N+ L L DYM+P V I + P+ NGK+ Sbjct: 913 KKEASGINPLVAYYVSQKESNVTDENLRDFLKKKLPDYMMPLVFISLAEFPLTPNGKI 970 >UniRef50_Q4KES9 Cluster: Nonribosomal peptide synthetase; n=6; Bacteria|Rep: Nonribosomal peptide synthetase - Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) Length = 4887 Score = 113 bits (272), Expect = 3e-24 Identities = 62/176 (35%), Positives = 96/176 (54%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P++N +YLLD R V G GE+ V G +ARGY+ RF+ +P + P Sbjct: 853 IGRPVANARIYLLDSQQRPVPIGVAGELYVGGAGVARGYLNRPQLTAERFLDDPFSDQPE 912 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YR+GD L G I Y GR D QVKIRG R++L E++ + P + V+L Sbjct: 913 -ARMYRSGDLARWLADGRIDYLGRNDDQVKIRGVRIELGEIETRLCQFPGIQEAVLLARE 971 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + NP ++A+ T + + + A L + L DYM+P + ++ +P+ NGK+ Sbjct: 972 DQPGNPRLVAYFTQQQDVALDVAQLRAHLLAQLPDYMVPVAYVRLDALPLTANGKL 1027 Score = 106 bits (254), Expect = 4e-22 Identities = 60/176 (34%), Positives = 95/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+N +YLLD R V G GE+ V G +ARGY+ + RF+ +P +T P Sbjct: 1897 IGRPIANARIYLLDPQQRPVPIGVAGELYVGGAGVARGYLNRPELTAERFLEDPFSTVPG 1956 Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YR+GD G I Y GR D QVK+RG R++L E++ ++ +P + V+L Sbjct: 1957 -ARMYRSGDLARWRADGRIDYLGRNDDQVKVRGVRIELGEIETCLNRLPGIREAVLLARE 2015 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ + P A S + L L +YM+P + + +P+ NGK+ Sbjct: 2016 DQPGQTRLVAYFSATPGAEPSPAELRRRLLEQLPEYMVPAAYVHLAALPLTANGKL 2071 Score = 105 bits (252), Expect = 7e-22 Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200 PIG PI+N +YLLD M+ V G GE+ + G +ARGY+ + RF+ +P + P Sbjct: 2955 PIGKPIANTRIYLLDAQMQPVPRGVVGELYIGGVQVARGYLNREQLSAERFLKDPFSQEP 3014 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LYRTGD L G I Y GR D QVKIRG R++L E+ ++ + V VVL Sbjct: 3015 G-ARLYRTGDLARYLADGTIEYLGRNDDQVKIRGLRIELGEIQARLTQLEGVKEAVVLAR 3073 Query: 378 GVESSNPEILA-FVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A + T+ + ++ + + L L ++M+P + + + +P+ NGK+ Sbjct: 3074 EDVPGDQRLVAYYTTVAGQPALAVEQLRRALLEHLPEFMVPALFMHLAALPLSPNGKL 3131 Score = 87.4 bits (207), Expect = 2e-16 Identities = 56/184 (30%), Positives = 97/184 (52%), Gaps = 9/184 (4%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG P+SN VY+LD + + G GE+ + G +A GY+ D +F+ +P + Sbjct: 4031 SVPIGRPLSNTRVYVLDALGQPLPVGVVGELYIGGDGVALGYLNRPDLSAQKFLIDPFHQ 4090 Query: 195 HPNF----AKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359 A +YRTGD G L+ G++ GR D QVKIRG R++ E+ ++ P + + Sbjct: 4091 QTQGTAAPALMYRTGDLGRWLENGLLECIGRNDEQVKIRGLRIEPGEIQAQLARFPGLRD 4150 Query: 360 CVVLCYGVESSNPEILAFVTINPEA-RMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLV 533 V+ + ++A+ T++ A+ + + L L DYM+P + ++ +P+ Sbjct: 4151 GAVVVREDSPGDKRLVAYYTLHEHTPAPDAEQLRSHLQQQLPDYMVPLAYVHLQALPLTR 4210 Query: 534 NGKV 545 NGK+ Sbjct: 4211 NGKL 4214 >UniRef50_Q4ZT69 Cluster: Amino acid adenylation; n=8; cellular organisms|Rep: Amino acid adenylation - Pseudomonas syringae pv. syringae (strain B728a) Length = 5372 Score = 113 bits (271), Expect = 3e-24 Identities = 69/184 (37%), Positives = 104/184 (56%), Gaps = 9/184 (4%) Frame = +3 Query: 21 TVP-IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 T+P IG P++N +YLLDE+MR V G GE+ + G +ARGY+ D RFI +P Sbjct: 1900 TLPSIGQPVANTRIYLLDEHMRPVPVGVAGELYIGGVCVARGYLNRDDLTADRFIADPFA 1959 Query: 192 THPN---FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359 T + A+LY+TGD G D G I+Y GR D Q+KIRG R++L E++ + P + + Sbjct: 1960 TREDGNPCARLYKTGDLGCWQDDGNIIYMGRNDDQIKIRGFRIELGEIEARLGQYPGLRD 2019 Query: 360 CVVLCYGVESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLV 533 VL ++A+ ++ +A A ++ L + L DYMIP + +E +PV Sbjct: 2020 AAVLAREDVPGEKRLVAYFSVQAGQALPEADHMRLHLQAVLPDYMIPAAYVHLEKLPVSP 2079 Query: 534 NGKV 545 NGK+ Sbjct: 2080 NGKL 2083 Score = 110 bits (265), Expect = 2e-23 Identities = 66/180 (36%), Positives = 100/180 (55%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++ IG PI+N VYLLDE+ + V G GE+ VAG +ARGY+ + RF+ +P + Sbjct: 4024 SLDIGKPITNTRVYLLDEHQQLVPLGVAGELYVAGEGVARGYLNRPEMTAERFLRDPFHC 4083 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + A++YRTGD + G + Y GR D QVKIRG RV+L E++ +S +P ++ +VL Sbjct: 4084 DAD-ARMYRTGDLARWNADGTLDYLGRNDDQVKIRGLRVELGEIEAQLSQLPGIEEALVL 4142 Query: 372 CYGVESSNPEILA-FVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E P + A F+ + M + A L + L YM+P + + P+ NGKV Sbjct: 4143 AREDEPGQPRLAAYFIERDGSLSMPVSELRAALLAVLPGYMVPSAFVRLAAWPLTANGKV 4202 Score = 108 bits (259), Expect = 9e-23 Identities = 62/177 (35%), Positives = 95/177 (53%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+ N YLLDE + V G GE+ + G +ARGY+ D RF+ + + HP Sbjct: 5100 IGKPVGNTQFYLLDEQQQLVPLGVAGEIYIGGAGVARGYLNRDDLTAERFLADTFSRHPQ 5159 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD G L G I Y GR D QVKIRG R++L E+D ++ P V VV Sbjct: 5160 -ARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTARE 5218 Query: 381 VESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A+ T+ + + + ++ L L YM+P + ++ +P+ NGK+ Sbjct: 5219 DVPGDKRLVAYYTVLSAQTEPAIDSLRGWLLGQLPAYMVPVAYVRLDAMPLTPNGKL 5275 Score = 107 bits (257), Expect = 2e-22 Identities = 61/180 (33%), Positives = 103/180 (57%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194 ++PIG P+ N+ +Y+LD + G GE+ + G +ARGY+ + +F+ +P ++ Sbjct: 2980 SIPIGKPVGNSRLYVLDNQGQPAPLGVGGELYIGGQGVARGYLHRDELTLEKFVADPFDS 3039 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LYRTGD G + Y GR D QVKIRG RV+L E++ ++ V VVL Sbjct: 3040 DPQ-ARLYRTGDLVRWRADGNLEYLGRNDEQVKIRGFRVELGEIEARLAEHAEVREAVVL 3098 Query: 372 CYGVESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 C + ++A+VT PE + +++ + L L DYM+P ++++++P+ NGK+ Sbjct: 3099 CRQDAPGDKRLVAYVTAQQPETALDIEHLRSHLQGLLPDYMVPAAYVQLDSLPLTANGKL 3158 Score = 95.1 bits (226), Expect = 9e-19 Identities = 60/177 (33%), Positives = 95/177 (53%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTHP 200 PIG I + +YLLD + G GE+ V G +ARGY+ + + RF+ +P + P Sbjct: 806 PIGKRIPDLQLYLLDAYGHPLPPGAVGELYVGGAGVARGYLNRDELNTTRFLDDPFASAP 865 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A++YR+GD G L G + Y GR D QVKIRG R++L E++ +S V + VV+ Sbjct: 866 G-ARMYRSGDLGRWLPDGSLEYLGRNDEQVKIRGFRIELGEIEARLSACEGVRDAVVVVR 924 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E + ++A+V A + +L SL ++M+P + +E P+ NGK+ Sbjct: 925 EDEPGDQRLVAYVIGTAGQEPDATWLREQLRLSLAEHMLPSAFVSLEAFPLTANGKL 981 >UniRef50_A7IZW1 Cluster: OciA; n=1; Planktothrix agardhii NIVA-CYA 116|Rep: OciA - Planktothrix agardhii NIVA-CYA 116 Length = 3477 Score = 113 bits (271), Expect = 3e-24 Identities = 61/178 (34%), Positives = 101/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V IG P+ N +Y+LD ++ V G PGE+ + G LAR Y+ + +FI NP + + Sbjct: 2109 VSIGRPVPNTQIYILDSYLQPVPIGVPGELHIGGAGLARSYLNRPELTQEKFIPNPFSNY 2168 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+ ++LY+TGD L G I Y GR D+QVKIRG R++L E++ ++ P V + V++ Sbjct: 2169 PD-SRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIETVLTQNPQVQSSVIIA 2227 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 N ++A++ +A + + L L +YMIP + +E++P+ NGK+ Sbjct: 2228 CEDTPGNKRLVAYIVPQKDATPTPNELRQFLKEKLPEYMIPSAFVILESLPLTPNGKI 2285 Score = 109 bits (262), Expect = 4e-23 Identities = 63/176 (35%), Positives = 100/176 (56%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+ + VYLLD+ ++ V G PGE+ V G +A+GY+ + RFI +P H N Sbjct: 3195 IGRPLPDLQVYLLDQYLQPVPVGVPGEMYVGGAGVAKGYLNRPELTTERFISSPFE-HSN 3253 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 KLY+TGD G + Y GR D+QVKIRG R++L E++ +++ P + VVL + Sbjct: 3254 --KLYKTGDLARYWPNGELEYLGRIDNQVKIRGFRIELGEIEALLASHPQIWETVVLVWD 3311 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A++ PE + I L + L DYM+P + +E +P+ NGK+ Sbjct: 3312 DTAGDKRLVAYIVPQPEITIIIDEIRQFLKAKLPDYMVPNAFVILEALPLTTNGKI 3367 >UniRef50_A0ZF79 Cluster: Non-ribosomal peptide synthase; n=6; Cyanobacteria|Rep: Non-ribosomal peptide synthase - Nodularia spumigena CCY 9414 Length = 2195 Score = 113 bits (271), Expect = 3e-24 Identities = 70/183 (38%), Positives = 106/183 (57%), Gaps = 8/183 (4%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFI----HN 182 T+PIG PISN +Y+L+E ++ V G PGE+ + G LARGY+ + RFI HN Sbjct: 353 TLPIGRPISNTQIYILNEQLQPVPVGTPGEIYIGGDGLARGYLNRPELTAERFISHPFHN 412 Query: 183 PHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359 P + N KLY+TGD L G I + GR D+QVKIRG R++L EV+ A+S P + Sbjct: 413 PKSKIQN-PKLYKTGDLARYLPDGNIEFVGRVDNQVKIRGFRIELGEVEAALSQHPDIQQ 471 Query: 360 CVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536 VV+ + ++A+V + +A ++A ++ L L YM+P + ++ +P+ N Sbjct: 472 AVVIVREDIPGDKRLVAYVVPDQKA-VTATTFKSFLEDKLPAYMVPTAWMLLDFLPLTPN 530 Query: 537 GKV 545 GKV Sbjct: 531 GKV 533 Score = 92.7 bits (220), Expect = 5e-18 Identities = 63/180 (35%), Positives = 98/180 (54%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +V IG PISN VY+LD+ + V G PGE+ + G LARGY + + +FI NT Sbjct: 1440 SVSIGKPISNAQVYILDQYQQTVPIGVPGELHIGGAGLARGYWQRPELTAEKFI---ENT 1496 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 N +LY+TGD + G + Y GR D+QVKIRG R++L E++ + P V VV+ Sbjct: 1497 EGN--RLYKTGDLVKFRRDGNLEYLGRVDNQVKIRGFRIELGEIETVLRQHPQVSQAVVI 1554 Query: 372 CYGVESSNPEILA-FVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A F+ P+ + + L L +YMIP + ++++P+ N KV Sbjct: 1555 AHQEITGQKRLVAYFLPQGPQPTID--ELRQFLKQKLPNYMIPAAFMVLDSIPMTPNQKV 1612 >UniRef50_Q0AY10 Cluster: Non-ribosomal peptide synthetase modules and related proteins-like protein; n=1; Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep: Non-ribosomal peptide synthetase modules and related proteins-like protein - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 2638 Score = 112 bits (270), Expect = 4e-24 Identities = 58/182 (31%), Positives = 106/182 (58%), Gaps = 5/182 (2%) Frame = +3 Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD---PHRFIHNP 185 + VPIG P+SN +Y+LD+ R + G PGE+C++G+ ++RGY+ G+D +++ NP Sbjct: 947 YANVPIGKPLSNTDLYILDKQGRQMPVGVPGELCISGYQVSRGYL-GRDDLTAEQYVANP 1005 Query: 186 HNTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 +N + + Y+TGD L G + + GR D QVKIRG RV+L E++ + P + + Sbjct: 1006 YNRAEGYERYYKTGDVCRWLPDGNMEFVGRRDFQVKIRGFRVELSEIEGKIREYPGILDA 1065 Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNG 539 V+ Y + A++ + + +++ ++ + L YM+P V +++ ++P+ NG Sbjct: 1066 TVVAYDEAGGGKYVAAYIVADHQVKIA--DLNDFIAQDLPAYMVPAVTMQLASIPLNQNG 1123 Query: 540 KV 545 KV Sbjct: 1124 KV 1125 Score = 83.0 bits (196), Expect = 4e-15 Identities = 56/178 (31%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 + IG P+SN +Y+++EN + + G PGE+ +AG + RGYV + +FI Sbjct: 1971 ITIGKPMSNVQIYMINENHKILPAGAPGELVIAGAGVGRGYVNKPEMTAEKFI------T 2024 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 N + YR+GD + G I + GR D QVK+RG RV+L E++ ++ + + +V+ Sbjct: 2025 INGRRAYRSGDLARWNFNGEIEFHGRIDDQVKLRGLRVELGEIEKVMNDYEGILSSIVV- 2083 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + A+ T +A + L +LT YM+P V I+++ +P+ NGKV Sbjct: 2084 VKENQAGQFLCAYFTAQGIVDKAA--LTQHLADTLTYYMVPSVLIQLDKLPLTNNGKV 2139 >UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC 7120|Rep: All1695 protein - Anabaena sp. (strain PCC 7120) Length = 1449 Score = 112 bits (269), Expect = 6e-24 Identities = 67/180 (37%), Positives = 103/180 (57%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++PIG PI+N VY+LD+ ++ V G GE+ + G LARGY+ D +FI +P + Sbjct: 343 SIPIGRPIANTQVYILDDVLQLVPIGIAGELYIGGDGLARGYLNKPDLTAEKFIPHPFSD 402 Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 PN ++LY+TGD L G I + GR D QVKIRG RV+L E++ ++ P V + VVL Sbjct: 403 KPN-SRLYKTGDRVRWLPDGTIEFLGRIDFQVKIRGFRVELGEIEAILAQHPSVRSAVVL 461 Query: 372 CYGVESSNPEILAFVTINPEAR-MSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++ ++A+ T ++ + L L +YMIP I +E +P+ NGKV Sbjct: 462 AQEYQPADKRLVAYFTREENCNTVAPSELRHFLQQKLPNYMIPSAFISLEKLPLNANGKV 521 >UniRef50_Q333V5 Cluster: NRPS protein; n=2; Actinomycetales|Rep: NRPS protein - Micromonospora sp. ML1 Length = 596 Score = 112 bits (269), Expect = 6e-24 Identities = 66/178 (37%), Positives = 101/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 + IG P S N VY+LDE +R V G GE+ +AG LARGY+ G RF+ +P Sbjct: 313 ITIGTPWSGNRVYVLDERLRPVPNGRDGELYLAGNGLARGYLNRPGLTASRFVLDPFG-- 370 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YR+GD G G +++A R D QVKIRG RV+L EV+ ++ P VD V+ Sbjct: 371 PPGGRMYRSGDRGHRRADGQLVFASRGDDQVKIRGFRVELGEVEARLAAHPAVDVAAVVV 430 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 G + + + AFV+ +SA + A +L ++M+P +++ + +PV NGK+ Sbjct: 431 VG-DLAGARLAAFVSTVAGTGVSAAELSAHSAETLPEHMVPSSVQVLQRLPVTANGKI 487 >UniRef50_Q18BS4 Cluster: Putative nonribosomal peptide synthetase; n=3; Clostridium difficile|Rep: Putative nonribosomal peptide synthetase - Clostridium difficile (strain 630) Length = 729 Score = 112 bits (269), Expect = 6e-24 Identities = 63/180 (35%), Positives = 101/180 (56%), Gaps = 6/180 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 +PIG PI N Y Y+LD+ + G PGE+C++G ++RGY+ +G F+ NP+ T Sbjct: 543 IPIGKPIFNTYAYVLDKKNKLCPIGAPGELCLSGIQISRGYLNKKGLTEQVFVKNPYKTC 602 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + +YRTGD LD G + Y GR D+QVKI R++L E+++ ++ I + + V + Sbjct: 603 EHNKLMYRTGDLVRWLDDGNLDYIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCIS 662 Query: 375 YGVESSNPEILAFVTINPE--ARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545 + + I A+ I+ E +++ + I L L YMIP +I I+ +PV GKV Sbjct: 663 RTNDDGDMYICAYYVIDEEDSGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKV 722 >UniRef50_Q0RI59 Cluster: Non-ribosomal peptide synthetase; n=3; cellular organisms|Rep: Non-ribosomal peptide synthetase - Frankia alni (strain ACN14a) Length = 1531 Score = 112 bits (269), Expect = 6e-24 Identities = 63/178 (35%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VP+G P++N ++LDEN+R G PGE+ + G LARGY+ G RF+ +P+ Sbjct: 759 VPVGSPVANTTCHVLDENLRLAPLGVPGELYIGGAQLARGYLNRPGLSASRFVADPYG-- 816 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LYRTGD L G + + GR D QVKIRGHRV+L E++ + P V V Sbjct: 817 PPGARLYRTGDLMRRLPSGALQFLGRVDDQVKIRGHRVELGEIESVLLAAPGVAQATVAA 876 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + A++ + A+ A + A ++L D+M+P + + +P+ +GKV Sbjct: 877 RTDGPGGRYLAAYLVLADGAQPDAAALRAHAAATLPDHMVPATLTFLPALPLSPSGKV 934 >UniRef50_Q08MM0 Cluster: Linear gramicidin synthetase subunit B; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Linear gramicidin synthetase subunit B - Stigmatella aurantiaca DW4/3-1 Length = 746 Score = 112 bits (269), Expect = 6e-24 Identities = 64/178 (35%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VP+GVP+ VY+LDE M+ V EG GE+ G LARGYV + +F+ NP+ Sbjct: 435 VPLGVPLDGTDVYVLDEEMQPVPEGVVGELYTGGDGLARGYVGRPELTAEKFVPNPYGKQ 494 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD G + + GRAD+QVK+RG R+++ EV+ A+ + P V V+ Sbjct: 495 AG-QRLYRTGDLARWRGDGSLEFVGRADTQVKVRGFRIEIGEVEGALESHPEVKAAAVVV 553 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 G + ++ FV + ++ + L L +YM+P ++E+E +P+ NGKV Sbjct: 554 QGEGAEGKRLVGFV-VGGGRKVEVGEVRGYLEKRLPEYMVPSLLVEVEKLPLTGNGKV 610 >UniRef50_A0UVH5 Cluster: Amino acid adenylation domain; n=2; Bacteria|Rep: Amino acid adenylation domain - Clostridium cellulolyticum H10 Length = 2193 Score = 112 bits (269), Expect = 6e-24 Identities = 67/178 (37%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI N +Y+LD N + V G GE+ VAG LA+GY+ + RF+ NP++T Sbjct: 1896 VPIGRPIDNTEIYILDSNKQLVPIGVAGELYVAGDGLAKGYLNRPELTKERFVPNPYDTS 1955 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +YR GD L G I Y GR D+QVKIRG RV+ E++ + P V VV+ Sbjct: 1956 ---GLMYRMGDMARYLPDGNIEYLGRGDNQVKIRGIRVESGEIESVLLKFPSVKEAVVVS 2012 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 YG + + A++ N + + + L++YMIP I +E +P+L NGK+ Sbjct: 2013 YGEAKGDVRLAAYIVPNVTV-PEVDELRSFIRGYLSEYMIPASINFVEHMPLLPNGKI 2069 Score = 111 bits (268), Expect = 8e-24 Identities = 68/179 (37%), Positives = 99/179 (55%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI N +Y+LD N + V G GE+ VAG LA+GY+ + RF+ NP++T Sbjct: 836 VPIGRPIDNTEIYILDSNKQPVPIGVAGELYVAGDGLAKGYLNRPELTEERFVPNPYDTS 895 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +YR GD L G I Y GR D+QVKIRG RV+L E++ + P V VV+ Sbjct: 896 ---GLMYRMGDMARYLPDGNIEYLGRGDNQVKIRGIRVELGEIESVLLKFPSVKEAVVVS 952 Query: 375 YGVESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 YG + + A++ P+ + + + + L +YMIP I +E +P+L NGK+ Sbjct: 953 YGELKGDVRLAAYIV--PDVTVPEVDELRSFIRGYLPEYMIPVSINFVEHIPLLPNGKI 1009 >UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep: Peptide synthetase 2 - Bacillus subtilis Length = 2560 Score = 112 bits (269), Expect = 6e-24 Identities = 61/176 (34%), Positives = 98/176 (55%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+S +++D +M G PGE+ + G +ARGY+ + RF+ NP+ Sbjct: 1815 IGRPLSTLQAHVMDAHMNLQPTGVPGELYIGGEGVARGYLNRDELTADRFVSNPYLPGD- 1873 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LYRTGD L G + Y GR D QVK+RGHR++L E+ A+ P + V+ Sbjct: 1874 --RLYRTGDLAKRLSNGELEYLGRIDEQVKVRGHRIELGEIQAALLQYPMIKEAAVITRA 1931 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E I A++ I + + +I L ++L D+M+P ++I+I+++PV VNGK+ Sbjct: 1932 DEQGQTAIYAYMVIKDQQAANISDIRTYLKNALPDFMLPARMIQIDSIPVTVNGKL 1987 Score = 104 bits (250), Expect = 1e-21 Identities = 64/178 (35%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 + IG PI N V++L N + G GE+C++G LARGY + ++ + HP Sbjct: 776 ITIGHPIRNTKVFVLHGN-QMQPIGAAGELCISGAGLARGYYKQQE---LTQKAFSDHPF 831 Query: 204 FA--KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD G L G I Y GR D QVKIRG+R++L+E++ + P V VL Sbjct: 832 LEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIRGYRIELREIETVLRQAPGVKEAAVLA 891 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 V + E++A++ PE S ++ L +L YMIP +I I +P+ +GK+ Sbjct: 892 RDVSAEEKELVAYIV--PEKGNSLPDLYQHLAGTLPSYMIPASIINISQMPLTSSGKL 947 >UniRef50_Q3M5M7 Cluster: Amino acid adenylation; n=1; Anabaena variabilis ATCC 29413|Rep: Amino acid adenylation - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 1786 Score = 111 bits (268), Expect = 8e-24 Identities = 58/176 (32%), Positives = 102/176 (57%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+N +Y+LD++++ V G GE+ + G LA+GY+ + +FI +P + P Sbjct: 1485 IGRPIANTQIYILDQHLQPVPIGVTGELHIGGNGLAQGYLHRPELTAEKFIAHPFSNQPT 1544 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LY+TGD G I + GR D QVKIRG R++L E++ A++ P V CVV+ Sbjct: 1545 -ARLYKTGDLARYRSDGTIEFIGRIDHQVKIRGFRIELGEIETALNQHPQVRECVVIASD 1603 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++ ++ A++ + + ++ + + L L +YMIP ++E +P+ N K+ Sbjct: 1604 DQLAHQQLQAYIVFHQQLKVDSSELHRFLKQKLPEYMIPTSFFQLENIPLTPNAKI 1659 >UniRef50_O07944 Cluster: Pristinamycin I synthase 3 and 4; n=2; Streptomyces|Rep: Pristinamycin I synthase 3 and 4 - Streptomyces pristinaespiralis Length = 4848 Score = 111 bits (268), Expect = 8e-24 Identities = 67/182 (36%), Positives = 101/182 (55%), Gaps = 8/182 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNTH 197 VPIG P+ N Y+LDE +R V G GE+ +AG LARGY + RF +PH H Sbjct: 4307 VPIGRPLDNTRAYVLDERLRPVPPGVTGELYIAGAGLARGYWDQSARTAERFTADPH-AH 4365 Query: 198 ---PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 ++YRTGD D GV+ + GRAD QVKIRG R++ E++ A++ P V Sbjct: 4366 LFGDTGGRMYRTGDLARRDADGVLHFCGRADQQVKIRGFRIEPGEIETALAAHPDVTRAA 4425 Query: 366 VLCYGVESSNPEILAFVTINPEA-RMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNG 539 V+ + + ++A++ P+A +A+ + A L + L DYM+P + + +PV NG Sbjct: 4426 VVARPGRAGDKVLVAYLVTAPDAGDTTAEQLRAGLETQLPDYMVPAAFVALPALPVTPNG 4485 Query: 540 KV 545 K+ Sbjct: 4486 KL 4487 Score = 109 bits (263), Expect = 3e-23 Identities = 64/179 (35%), Positives = 104/179 (58%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNT 194 + PIG P+ ++ VY+LD +R V G GE+ +AG +ARGY+ RF+ +P+ Sbjct: 3252 SAPIGRPVDHDRVYVLDSALRPVPPGVTGELYLAGAGVARGYLHRPRTTAERFVADPYAP 3311 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A++YRTGD G + +G + +AGRAD QVKIRG RV+ EV+ A++ P + VL Sbjct: 3312 RPG-ARMYRTGDLGRWNTRGELEFAGRADHQVKIRGFRVEPGEVEAALTAHPRITQAAVL 3370 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 +G ++A+V + ++ + L + L D+M+P + +E +P+ VNGK+ Sbjct: 3371 AHG-----DRLVAYVVTTADRDLT--GVREHLAARLPDFMVPTAYVRLEALPLTVNGKL 3422 Score = 107 bits (256), Expect = 2e-22 Identities = 59/177 (33%), Positives = 102/177 (57%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200 P+G P+S VY+LD +R V G GE+ +AG ++RGY+ RF+ +P+ P Sbjct: 772 PLGRPVSGARVYVLDSALRPVAPGVTGELYLAGAGVSRGYLNRPVLTAERFVADPYAPSP 831 Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A++YRTGD G + +G + +AGRAD QVKIRG R++ E++ A++ +P V V+ Sbjct: 832 G-ARMYRTGDLGRWNTRGELEFAGRADHQVKIRGFRIEPGEIEAALTDLPAVARAAVVVR 890 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A+ E + A + + L +L D+M+P ++ ++ +P+ NGK+ Sbjct: 891 EDRPGDKRLVAYAVPAGEG-LDAAAVRSRLARTLPDFMVPAAIVALDALPLTPNGKL 946 Score = 84.6 bits (200), Expect = 1e-15 Identities = 49/136 (36%), Positives = 78/136 (57%), Gaps = 5/136 (3%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT-- 194 PIG P+++ VY+LDE +R V G GE+ V+G +ARGY+ RF+ +P+ Sbjct: 1811 PIGRPVAHARVYVLDERLRPVPPGVTGEMYVSGAGVARGYLHRPALTAQRFVPDPYALLF 1870 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 ++YRTGD LD G + +AGRAD QVKIRG R++ E++ ++ P V V+ Sbjct: 1871 GETGTRMYRTGDLARLDADGRLHFAGRADQQVKIRGFRIEPGEIETVLTAHPAVAAGAVI 1930 Query: 372 CYGVESSNPEILAFVT 419 + +++A++T Sbjct: 1931 AREDTPGDKQLVAYLT 1946 >UniRef50_A6ASZ6 Cluster: Enterobactin synthetase component F; n=2; Vibrio harveyi|Rep: Enterobactin synthetase component F - Vibrio harveyi HY01 Length = 1315 Score = 111 bits (268), Expect = 8e-24 Identities = 62/180 (34%), Positives = 101/180 (56%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++PIG P+ N +Y+LD+ + V G G + +AG LA+GY + RFI NP Sbjct: 777 SIPIGRPVWNTQIYILDDALNPVPPGVVGHLYIAGRQLAQGYYGQPELTAERFIDNPFG- 835 Query: 195 HPNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +++Y +GD + G I Y GR+D QVKIRG R++L+E+++A++ P V VL Sbjct: 836 -PQGSRMYLSGDLARWREDGAIEYCGRSDFQVKIRGFRIELEEIENALANHPSVAQVAVL 894 Query: 372 CYGVESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+VT N E + + ++ L L +YM+P +E+E P+ NGK+ Sbjct: 895 AQEYNDGDKRLVAYVTAENTEQGIDSNALQTYLAEPLPEYMVPSYFVELEAFPLTPNGKL 954 >UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1; Brevibacillus texasporus|Rep: Nonribosomal peptide synthetase F - Brevibacillus texasporus Length = 2491 Score = 111 bits (267), Expect = 1e-23 Identities = 67/178 (37%), Positives = 100/178 (56%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI+N+ VY+LD+N G PGE+CV+G LARGY+ + RF+ NP P Sbjct: 768 PIGKPITNHSVYILDQNRHLQPIGIPGELCVSGAGLARGYLNQPELTVERFVDNPF--VP 825 Query: 201 NFAKLYRTGDF--GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD +D G I Y GR D QVKIRG+R++L E++ + P + +V+ Sbjct: 826 G-ERMYRTGDLVRWRID-GSIEYLGRIDEQVKIRGYRIELGEIETKLLEHPSISEALVVA 883 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E + A+V S ++ L +L +YMIP ++E+E +P+ NGK+ Sbjct: 884 RNDEQGYTYLCAYVVAT--GAWSVSSLREHLIETLPEYMIPAYMMEVEKMPLTANGKI 939 Score = 101 bits (241), Expect = 1e-20 Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG P+ N V++L + + G GE+CV+G LARGY+ + RF+ NP Sbjct: 1802 IPIGRPLHNTTVHILSADDKLQPIGVIGELCVSGEGLARGYLNLPELTMERFVENPFR-- 1859 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD L GV+ Y GR D QVKIRGHR++L E++ + P + V+L Sbjct: 1860 PG-ERMYRTGDLARWLPDGVLEYVGRKDEQVKIRGHRIELSEIETRILEHPAISETVLLA 1918 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E + + A++ + + + + + + L ++M+P I ++ +P+ NGKV Sbjct: 1919 KRNEQGSSYLCAYIVAH--GQWNIQELRKHVRDVLPEHMVPSYFIGLDKLPLTSNGKV 1974 >UniRef50_A3KFG5 Cluster: PstC protein; n=2; Actinomycetales|Rep: PstC protein - Actinoplanes friuliensis Length = 6661 Score = 111 bits (267), Expect = 1e-23 Identities = 65/176 (36%), Positives = 98/176 (55%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG PI+N VY+LD +R V G PGEV +AG + RGY + RF+ NP+ T Sbjct: 2813 IGTPIANTQVYVLDAALRPVPAGVPGEVYIAGDGVVRGYWQRPALTAQRFVANPYGT--T 2870 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++ YRTGD G G + Y RAD QVK+RG+R++L E++ ++ P V VL Sbjct: 2871 GSRFYRTGDIGRWAADGTLEYLSRADDQVKLRGYRIELGEIEAVLAADPAVVQAAVLVRE 2930 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A+V R SA + + SL +YM+P ++E++T P+ NGK+ Sbjct: 2931 DRPGDKRLVAYV------RGSADGLRERIARSLPEYMVPAAIVELDTFPLTPNGKL 2980 Score = 109 bits (262), Expect = 4e-23 Identities = 67/178 (37%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P N Y+LDE +R V G GE+ VAG LARGY + G RF+ NP Sbjct: 1782 VPIGRPFWNTQAYVLDERLRPVPPGVTGELYVAGVVLARGYWQRPGLTAERFVANPFGAA 1841 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD + G ++YAGRAD+QVK+RG R++L E++ ++T P V VL Sbjct: 1842 GT--RLYRTGDRARWNADGNLVYAGRADAQVKVRGFRIELGEIEAVLTTDPAVTQAAVLV 1899 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+V R S + + +L DYM+P + ++ P+ NGK+ Sbjct: 1900 REDQPGDKRLVAYV------RGSVDGLRERVAQALPDYMVPAAFVALDEFPLTPNGKL 1951 Score = 104 bits (250), Expect = 1e-21 Identities = 63/176 (35%), Positives = 96/176 (54%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG PI+N VY+LD +R V G GEV +AG + RGY + G RF+ NP+ T Sbjct: 4855 IGSPIANTQVYVLDAALRPVPAGVAGEVYIAGDGVVRGYWQRPGLTAQRFVANPYGT--T 4912 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++ YRTGD G G++ Y RAD QVK+RGHR++L E++ ++ V V+ Sbjct: 4913 GSRFYRTGDIGRWAADGMLEYLSRADDQVKLRGHRIELGEIEAVLAADAAVAQAAVIVRE 4972 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V R SA + ++L YM+P +E++T P+ NGK+ Sbjct: 4973 DRPGDKRLVAYV------RGSADGLRDRAAAALPGYMVPAAFVELDTFPLTPNGKL 5022 Score = 103 bits (247), Expect = 3e-21 Identities = 64/178 (35%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P N Y+LD ++ V G GE+ VAG LARGY + G RF+ NP Sbjct: 3826 VPIGRPFWNTQAYVLDAALQPVSAGVTGELYVAGVVLARGYWQRPGLTAERFVANPFGA- 3884 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +LYRTGD + G ++Y GRAD QVK+RG R++L E++ ++T P V V+ Sbjct: 3885 PG-TRLYRTGDLVRWNADGTLVYLGRADGQVKLRGFRIELGEIEAVLTTDPAVTQAAVVV 3943 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+V R S + + +L DYM+P + ++ P+ NGK+ Sbjct: 3944 REDQPGDKRLVAYV------RGSVDGLRERVAQALPDYMVPSAFVALDEFPLTPNGKL 3995 Score = 102 bits (245), Expect = 5e-21 Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VP+G P N VY+LD +R V G PGE +AG LARGY R G RF+ NP + Sbjct: 764 VPVGRPFWNTRVYVLDAGLRPVPAGVPGEAYIAGTGLARGYWRRPGLSAERFVANPFD-G 822 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YRTGD + G + + GR D QVK+RG+R++L E++ ++ V VL Sbjct: 823 PG-ARMYRTGDVVRWNTDGQLEFVGRGDGQVKLRGYRIELGEIESVIAADDAVTQAAVLV 881 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V R +A + + L DYM+P + ++ P+ NGK+ Sbjct: 882 REDRPGDKRLVAYV------RGNADGLRERVAELLPDYMVPAAFVVLDVFPLTPNGKL 933 Score = 100 bits (240), Expect = 2e-20 Identities = 58/178 (32%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P+ N VY+LDE ++ V G GE+ +AG +ARGY+ G RF+ +P Sbjct: 5898 VPIGAPLWNTRVYVLDERLQPVAPGVKGELYLAGAGVARGYLGRPGLTGQRFVADPFTGS 5957 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD D G +++AGR D QVK+RG RV+ E++ + P V V+ Sbjct: 5958 GE--RMYRTGDVVSWDADGRLIFAGRVDDQVKLRGFRVEPGEIEAVLRQRPEVAEAAVIL 6015 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+V ++ + ++L DY++P V+ ++ +P+ NGK+ Sbjct: 6016 REDRPGDKRLVAYVVTAAAFSAHPDDLRRHVAATLPDYLVPSAVVLVDVLPLTANGKL 6073 >UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1; Alcanivorax borkumensis SK2|Rep: Peptide synthetase, putative - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 3600 Score = 111 bits (266), Expect = 1e-23 Identities = 66/179 (36%), Positives = 108/179 (60%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVPIG PISN +Y+LD ++ V G PGE+ +AG LARGY D RF+ NP+ Sbjct: 3312 TVPIGAPISNIQLYVLDTDLNPVPRGVPGELYLAGIGLARGYFGRSDLTAERFVPNPYGD 3371 Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +++YRTGD G+I Y GR D QVKIRG R++L E++ + +P V++ VV+ Sbjct: 3372 AG--SRMYRTGDQVRQRGDGIIEYLGRLDHQVKIRGLRIELGEIEQQLKQLPDVNDAVVV 3429 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ + +++A+V+ + + R + + L +L +YM+P + + +E +P+ NGK+ Sbjct: 3430 ADHSDTGD-QLVAYVSADSDNR---EVWQQALADALPEYMVPALFMVLEALPLSPNGKL 3484 Score = 89.0 bits (211), Expect = 6e-17 Identities = 61/178 (34%), Positives = 92/178 (51%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAG-FNLARGYVRGKD--PHRFIHNPHNTH 197 PIG + +Y+LD+++ V G GE+ + LARGY + D RF+ +P Sbjct: 2267 PIGHAVGPRKLYVLDQDLNRVPVGVAGELYIGNEVGLARGYHQRPDLTAERFLPDPFG-E 2325 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD D GV+ Y GR D QVKIRG R++L E++ + P V VVL Sbjct: 2326 PG-ERMYRTGDLVKYRDDGVMEYLGRVDQQVKIRGFRIELGEIESRLLAHPQVREAVVLA 2384 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ ++ P +S + A L SL DYM+P ++ +E +P+ GKV Sbjct: 2385 Q-PSPGGDRLVGYLV--PRGPLSTDALIATLAESLPDYMVPSHLLTLEAMPLTPAGKV 2439 Score = 81.8 bits (193), Expect = 9e-15 Identities = 59/183 (32%), Positives = 93/183 (50%), Gaps = 10/183 (5%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAG-FNLARGYVRGKD--PHRFIHNPHNTH 197 PIG + +Y+LD+++ V G GE+ + LARGY + D RF+ +P Sbjct: 786 PIGHAVGPRKLYVLDQDLNRVPVGVAGELYIGNEVGLARGYHQRPDLTAERFLPDPFG-E 844 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD D GV+ Y GR D QVKIRG R++L E++ + + V+ Sbjct: 845 PG-ERMYRTGDLVKYRDDGVMEYLGRVDQQVKIRGFRIELGEIESQLLGHEQIREAAVVA 903 Query: 375 YGVESSNPEILAFVTINPEARM-----SAKNIEAELTSSLTDYMIP-QVIEIETVPVLVN 536 + ++ ++ + A + I A L+ SL DYM+P Q+I +E +P+ Sbjct: 904 Q-PSPTGDRLVGYIVMRNAAHSVPREHDPQTILAALSESLPDYMVPSQLITLEAMPLTPA 962 Query: 537 GKV 545 GKV Sbjct: 963 GKV 965 >UniRef50_UPI000038DECD Cluster: COG1020: Non-ribosomal peptide synthetase modules and related proteins; n=1; Nostoc punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide synthetase modules and related proteins - Nostoc punctiforme PCC 73102 Length = 1141 Score = 110 bits (265), Expect = 2e-23 Identities = 60/180 (33%), Positives = 101/180 (56%), Gaps = 7/180 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V IG P+ + VY+LDE+++ V GE GE+C+ G + +GYV + +F+ NP Sbjct: 338 VTIGKPLPDYSVYILDEHLQEVPLGEIGEICIGGIGVTQGYVNLPEQTASKFVTNPFEQS 397 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 K+YR+GD G + G I + GR D QVKIRG+R++L E++ + ++N +V Sbjct: 398 HKGEKIYRSGDLGRVTPDGEIEFLGRIDHQVKIRGYRLELTEIEAILLENQEIENAIVSL 457 Query: 375 YGVESSNPEILAFVTIN---PEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGK 542 + + E+ A++T++ + ++ L+S L YM+P I+I + +P L NGK Sbjct: 458 VSINDAVKELAAYITLHIPVTDPEALKYSLYTSLSSRLPSYMVPAFIDILDAIPTLPNGK 517 >UniRef50_Q93N87 Cluster: Peptide synthetase; n=12; Bacteria|Rep: Peptide synthetase - Streptomyces lavendulae Length = 4898 Score = 110 bits (265), Expect = 2e-23 Identities = 64/178 (35%), Positives = 103/178 (57%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +P+G P++N VY+LD ++ V G GE+ +AG LARGY++ G RF+ P Sbjct: 2260 LPVGSPLANRQVYVLDAFLQPVPPGVAGELYIAGAGLARGYLKRAGLSAERFVACPF--- 2316 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + ++YRTGD D G + +AGRAD+QVKIRG RV+L EV+ A++ P V VV+ Sbjct: 2317 ADGERMYRTGDLARWTDDGELAFAGRADAQVKIRGFRVELGEVEAALAAQPAVAQAVVVA 2376 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ ++ + + + + A L +L DYM+P ++ ++ +P+ VNGKV Sbjct: 2377 REGRPGEKRLVGYL-VPHGGQPDSDVLRARLAQTLPDYMVPAALVVLDALPLTVNGKV 2433 Score = 98.3 bits (234), Expect = 1e-19 Identities = 60/178 (33%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +P+G P+ N VY+LD + V G GE+ +AG LARGY++ G RF+ P Sbjct: 765 LPVGRPLGNRQVYVLDAYLHPVAPGVTGELYIAGAGLARGYLKRAGLSSERFVACP---F 821 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + ++YRTGD G +++ GRAD+QVK+RG RV+L EV+ A++ V + VV Sbjct: 822 ADGERMYRTGDLVRWTSDGELVFVGRADAQVKVRGFRVELGEVEAALAAEAGVGHAVVTA 881 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ +V + E + + + L L +YM+P +I ++ +P+ NGKV Sbjct: 882 REDRPGERRLIGYVLPDGE-DVDTELLREHLAKVLPEYMVPAALIVLDALPLTANGKV 938 Score = 86.2 bits (204), Expect = 4e-16 Identities = 50/119 (42%), Positives = 72/119 (60%), Gaps = 3/119 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 VP+G PI+N Y+LD +R V G GE+ VAG LARGY+ G RF+ +P Sbjct: 3783 VPVGRPIANGRTYVLDPFLRPVPPGVTGELYVAGAGLARGYLGQGGLTATRFVPDPFT-- 3840 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD G++++AGRAD+QVK+RGHR++ EV+ ++ P V V+ Sbjct: 3841 PG-ERMYRTGDLARWTHDGLLVFAGRADAQVKVRGHRIEPGEVEAVLAEHPGVAQAAVV 3898 >UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide synthetase/polyketide synthase; n=27; root|Rep: Non-ribosomal peptide synthetase/polyketide synthase - Myxococcus xanthus (strain DK 1622) Length = 14274 Score = 110 bits (265), Expect = 2e-23 Identities = 65/179 (36%), Positives = 97/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG P+SN Y+LD ++ V G PGE+ V G L RGYV D RFI P T Sbjct: 6127 SVPIGRPVSNTQAYVLDSQLQLVPVGVPGELYVGGEGLGRGYVSRPDLTAERFIPAPFAT 6186 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LYRTGD G + + GR D+QVK+RG R++L +V+ A+ T P V + Sbjct: 6187 QPG-ARLYRTGDLVRWRPDGTLEFIGRIDNQVKVRGFRIELADVEAALRTQPGVLEAAAV 6245 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ +A + + A + L +YM+P V + + T+P+ +GKV Sbjct: 6246 VREDIPGDKRLVAYAMGRDDAPLDVAALRAGMRQRLPEYMVPSVFVVLPTLPLSTSGKV 6304 Score = 106 bits (255), Expect = 3e-22 Identities = 67/179 (37%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNT 194 +V IG PI+N VY+LD MR G PGEV + G LARGY+ RF+ NP Sbjct: 4001 SVSIGRPIANTQVYVLDPAMRAAPVGVPGEVFIGGDGLARGYLGQPALTAERFVPNPFG- 4059 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LYR+GD L G + + GR D QVK+RG R++L E++ A+ + V+ + L Sbjct: 4060 -PPGARLYRSGDRARWLADGTLQFLGRVDFQVKLRGFRIELGEIETALRSHSEVETAIAL 4118 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+VT PE + ++ L L +YM+P V+ + T+P+ NGKV Sbjct: 4119 VREDSPGDRRLVAYVT--PE-DVDTASLREHLRQRLPEYMVPNAVVVLSTLPLSPNGKV 4174 Score = 102 bits (244), Expect = 6e-21 Identities = 66/180 (36%), Positives = 98/180 (54%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 L+VPIG PI N VY+LD + V G PGE+C+ G LARGY+ D F+ +P + Sbjct: 2941 LSVPIGRPIDNTEVYVLDPALCPVPVGVPGELCLGGPGLARGYLNRPDLTAECFVPHPFS 3000 Query: 192 THPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 P A+LYRTGD GV+ + GR D QVK+RG R++L E++ + P V V Sbjct: 3001 AVPG-ARLYRTGDRVRWRPDGVLEFLGRLDHQVKVRGFRIELGEIEAVLRAHPFVAEATV 3059 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + S + ++A+V + P+ ++ + L L DYM+P I ++ P+ GKV Sbjct: 3060 VVREDGSGSNRLVAYV-VPPQPDVAP--LREYLHQHLPDYMLPSAFIGLDAFPLTPTGKV 3116 Score = 101 bits (243), Expect = 8e-21 Identities = 62/181 (34%), Positives = 99/181 (54%), Gaps = 4/181 (2%) Frame = +3 Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH 188 F VPIG P++N +Y+LD + + G PGE+ + G + RGY + RFI + Sbjct: 9474 FHRVPIGRPVANTVLYVLDTHGQPAPVGIPGELHIGGVQVGRGYWQRPQLTAERFIPDAF 9533 Query: 189 NTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 + P A+LYRTGD L G + Y GRAD QVK+RG R++L E++ A+ P V + V Sbjct: 9534 SGIPG-ARLYRTGDVARWLPDGTLEYLGRADFQVKLRGFRIELGEIETALRMHPGVRDAV 9592 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542 + + ++A+VT A + A+ + A+L L +M+P + + +P+ +GK Sbjct: 9593 AVVREETRGDARLVAYVT-GDSAPLEAETLRAQLLKQLPQHMVPSTFVHLGVLPLTPSGK 9651 Query: 543 V 545 V Sbjct: 9652 V 9652 Score = 98.3 bits (234), Expect = 1e-19 Identities = 65/181 (35%), Positives = 99/181 (54%), Gaps = 4/181 (2%) Frame = +3 Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH 188 F VPIG P++N +Y+LD + + G PGE+ + G + RGY + RFI + Sbjct: 5059 FHRVPIGRPVANTVLYVLDVHGQPAPVGIPGELHIGGVQVGRGYWQRPQLTAERFIPDAF 5118 Query: 189 NTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 + P A+LYRTGD L G + Y GRAD QVK+RG R++L EV+ A+ V + V Sbjct: 5119 SGIPG-ARLYRTGDVARWLADGTLEYLGRADFQVKLRGFRIELGEVEAALRAHLDVFDAV 5177 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGK 542 + + ++A+VT P ++A + A L L +M+P IE + ++P+ NGK Sbjct: 5178 AVVREDAPGDQRLVAYVTGEPALDVAA--LRARLVEQLPAHMVPTAIETLPSLPLSPNGK 5235 Query: 543 V 545 V Sbjct: 5236 V 5236 Score = 95.9 bits (228), Expect = 5e-19 Identities = 62/176 (35%), Positives = 94/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG PI VY+LD + G GE+C+AG +ARGY G RFI + + P Sbjct: 12673 IGRPIVGTRVYVLDSRQQLAPLGTAGELCIAGEGVARGYFGRPGLTAERFIPDAFSGQPG 12732 Query: 204 FAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LYRTGD G + Y GR D QVK+RG R++L E++ A+ T V + VVL Sbjct: 12733 -ARLYRTGDKARWRHDGTLEYLGRLDFQVKVRGFRIELGEIEAALRTHGQVQDAVVLARE 12791 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V + ++A+++ L L +YM+P V + + +P+ GKV Sbjct: 12792 DVPGDKRLVAYVVGD---FITAESLRQHLLQRLPEYMVPSVFVPLAALPLTSTGKV 12844 Score = 91.9 bits (218), Expect = 9e-18 Identities = 55/152 (36%), Positives = 88/152 (57%), Gaps = 3/152 (1%) Frame = +3 Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH 188 F VPIG P++N +Y+LD + + G PGE+ + G + RGY + RFI + Sbjct: 1468 FHRVPIGRPVANTVLYVLDVHGQPAPVGIPGELHIGGVQVGRGYWQRPQLTAERFIPDAF 1527 Query: 189 NTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 + P A+LYRTGD L G + Y GRAD QVK+RG R++L E++ A++ P V + V Sbjct: 1528 SGIPG-ARLYRTGDVARWLPDGTLEYLGRADFQVKLRGFRIELGEIEAALAADPAVHDSV 1586 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEA 461 VL + + ++A+V ++ A +A+ ++A Sbjct: 1587 VLAREDSTGDQRLVAYVVLDDAA--AAQEVDA 1616 Score = 91.5 bits (217), Expect = 1e-17 Identities = 58/181 (32%), Positives = 100/181 (55%), Gaps = 7/181 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG ++N +Y+LD + V G PGE+ + G+ +ARGY+ + RF+ +P Sbjct: 11609 VPIGRALTNVRMYVLDRELEPVPPGVPGELFIGGWGVARGYLGRPELTAERFVPSP---F 11665 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + +LYRTGD + G + Y GR D+QVK+RG R++ E++ A+ P V + VV Sbjct: 11666 VDSERLYRTGDLARWRRDGNLEYLGRGDTQVKVRGVRIEPGEIEAALRAHPTVHDAVVHV 11725 Query: 375 YGVESSNPEILAFVTIN--PEA-RMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGK 542 + + ++A+V + P A ++ A + L +L +YM+P + + +P+ +GK Sbjct: 11726 REDVAGDKRLVAYVVPSSAPSAGQLEASALREHLRGNLPEYMVPGAFVSLAALPLTPSGK 11785 Query: 543 V 545 V Sbjct: 11786 V 11786 Score = 90.6 bits (215), Expect = 2e-17 Identities = 62/179 (34%), Positives = 93/179 (51%), Gaps = 7/179 (3%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHNTHP 200 IG PI Y+LD R G GE+ ++G LARGY +G+ RFI + + P Sbjct: 10538 IGRPIQGTRAYVLDARQRVAPAGIAGELYLSGDGLARGY-QGQPQLTAERFIPDAFSGTP 10596 Query: 201 NFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LYRTGD G + Y GR D QVK+RG R++L E++ + T V VVL Sbjct: 10597 G-ARLYRTGDKARWRHDGTLEYLGRLDFQVKLRGFRIELGEIEAVLRTHDQVQEAVVLVR 10655 Query: 378 GVESSNPEILAF--VTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ V + PEA ++A+ + L +YM+P + + T+P+ GKV Sbjct: 10656 EDVPGDKRLVAYVVVVVTPEAPVTAELLRQHAQERLPEYMVPSAFVLMGTLPLTPTGKV 10714 Score = 85.8 bits (203), Expect = 6e-16 Identities = 56/176 (31%), Positives = 91/176 (51%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG P++ ++LD + G GE+ +AG LARGY+ G RF+ +P + P Sbjct: 13732 IGKPLAGTRAFVLDARQQLAPLGTAGELYLAGDGLARGYLGQPGLTAERFVPHPFASTPG 13791 Query: 204 FAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LYRTGD G + Y GR D QVK+RG R++L E++ A+ V + VVL Sbjct: 13792 -ERLYRTGDKARWRHDGTLEYLGRLDFQVKLRGFRIELGEIEAALRAHEAVQDAVVLARE 13850 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A++ + A + A + L L +YM+P + + +P+ +GKV Sbjct: 13851 DVPGDKRLVAYI-VGGSATVEA--LRQHLQQRLPEYMVPPAFVSLPALPLNPSGKV 13903 Score = 40.3 bits (90), Expect = 0.028 Identities = 34/132 (25%), Positives = 59/132 (44%), Gaps = 4/132 (3%) Frame = +3 Query: 33 GVPISNNYVYLLDENMRC-VREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFA 209 G ++ + ++D R G+ GE+ V+G ++A+GY R + I Sbjct: 376 GSTLAEQRLLIVDPESRVPCAPGQVGEIWVSGGSVAQGYWRKPEDSVDIFQAVPVGAEAG 435 Query: 210 KLY-RTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTI-PCVDNCVVLCYG 380 Y RTGD G +L+ G ++ GR + +RG + Q+V+ V V + + Sbjct: 436 PKYLRTGDLGLLLEDGQLIVTGRRKDLIILRGRNLYPQDVESIVERAHRKVRPGCIAAFA 495 Query: 381 VESSNPEILAFV 416 +E+ E LA V Sbjct: 496 IETPEGEALAVV 507 >UniRef50_A4PHL4 Cluster: Non ribosomal peptide synthetase for virginiamycin S; n=3; Actinomycetales|Rep: Non ribosomal peptide synthetase for virginiamycin S - Streptomyces virginiae Length = 2671 Score = 110 bits (265), Expect = 2e-23 Identities = 64/179 (35%), Positives = 98/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194 TVPIG P+ N ++LD+ +R V G GE+ + G LARGY+ D RF+ +P T Sbjct: 1892 TVPIGSPLDNTTCHVLDQRLRPVPPGVTGELYIGGARLARGYLGRPDATAERFVADPSGT 1951 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A++YRTGD G++ + GRAD QVK+RG R++L E++ + P V VL Sbjct: 1952 -PG-ARMYRTGDLVRRRADGILEFLGRADHQVKVRGFRIELGEIESVIGRHPTVAQSAVL 2009 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + A+V A A + + +SL DYM+P V+ ++ +P+ NGK+ Sbjct: 2010 VREDRPGDKRVTAYVVPAAAAAADAGELRRHVAASLPDYMVPAAVVLLDRLPLTPNGKL 2068 Score = 81.8 bits (193), Expect = 9e-15 Identities = 54/177 (30%), Positives = 88/177 (49%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 +G P+++ ++LD +R G GE+ VAG LARGY+ RF+ +P + Sbjct: 831 VGAPLADLRAHVLDGALRPAPPGVTGELYVAGPGLARGYLGLPALTAERFVADPFAPAGD 890 Query: 204 F-AKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A++YRTGD G + Y GRAD QVKIRG R++L E++ A++ +P V + V Sbjct: 891 TGARMYRTGDLVRRRADGTLEYVGRADHQVKIRGFRIELGEIEAALAALPSVAHAAVTAR 950 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + A+ EL + L + +P ++ +P+ VNGK+ Sbjct: 951 EDTPGDRRLAAYAVPADGVPADPAAWRRELAAVLPAHQLPASFTPLDAIPLTVNGKL 1007 >UniRef50_Q8PKR8 Cluster: ATP-dependent serine activating enzyme; n=1; Xanthomonas axonopodis pv. citri|Rep: ATP-dependent serine activating enzyme - Xanthomonas axonopodis pv. citri Length = 1566 Score = 110 bits (264), Expect = 2e-23 Identities = 61/179 (34%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+PIG PI N VYLLD N + V G GE+C+AG + RGY+ + RF+ +P T Sbjct: 795 TIPIGRPIDNMRVYLLDANRQTVPAGVAGELCIAGSQVTRGYLNRPELTEQRFVVDPFGT 854 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++Y +GD + G + Y GR D Q+K+RG R++ EV + P V + V+ Sbjct: 855 GPE-QRMYCSGDLARWMPDGTLEYLGRNDDQIKLRGFRIEPAEVSSRILDNPLVADAAVV 913 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + S ++A+ ++ ++A+ + +L L DYM+P V I ++ +P+ NGK+ Sbjct: 914 IHTAASGEKCLVAYY-VSDAPEVTAERLREQLQQRLPDYMVPAVYIRMDLLPMTPNGKL 971 >UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3; Bacteria|Rep: Non-ribosomal peptide synthetase - Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) Length = 7523 Score = 110 bits (264), Expect = 2e-23 Identities = 61/179 (34%), Positives = 100/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T PIG PI+N +Y+LDE + V G GE+ + G +ARGY+ + RFI +P Sbjct: 4007 TPPIGRPIANTQIYILDEQKQPVPLGVAGEIYIGGAGVARGYLNRPELTAERFIADPFTD 4066 Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P+ A+LY+TGD G L G I Y GR D Q+K+RG R++L E++ + V VV+ Sbjct: 4067 TPD-ARLYKTGDLGRWLPNGDIDYLGRNDFQIKLRGFRIELGEIETHLIQCSGVGEAVVI 4125 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A++ P A + ++ +L+ L +YM+P + ++ P+ NGK+ Sbjct: 4126 AREDSTGDARLVAYLCPQPGAELHPTDLRQQLSRHLAEYMVPSAFVVLDVFPLTSNGKL 4184 Score = 107 bits (257), Expect = 2e-22 Identities = 59/176 (33%), Positives = 98/176 (55%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P++N +Y+LD + V G GE+ + G +ARGY+ D RFI +P + P Sbjct: 5085 IGKPLANTRLYILDAQDQPVPIGVTGELHIGGAGVARGYLHRPDLTAERFIPDPFSADPA 5144 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++Y+TGD L G I Y GR D Q+K+RG R++ E++ + P V + VV+ Sbjct: 5145 -ARIYKTGDLARWLPDGNIDYLGRNDFQIKVRGFRIEAGEIESRLLRCPGVQDAVVIARE 5203 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A++ P+A + + +L +SL DYMIP + ++ +P+ NGK+ Sbjct: 5204 DSPGDTRLVAYLCARPDAELHPAALRQQLAASLADYMIPSAFVTLDALPLTPNGKL 5259 Score = 106 bits (255), Expect = 3e-22 Identities = 61/183 (33%), Positives = 100/183 (54%), Gaps = 7/183 (3%) Frame = +3 Query: 18 LTVP---IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN 182 LT P IG PI+N +Y+LD R V G GE+ +AG + RGY+ D RFI + Sbjct: 7212 LTTPTPYIGHPIANTQIYILDAQGRVVPLGVAGEIHIAGAGVVRGYLGRPDLTAERFITD 7271 Query: 183 PHNTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359 P + P A++Y+TGD G L G + Y GR D QVK+RG R++L E++ ++ V + Sbjct: 7272 PFSGAPE-ARMYKTGDLGRWLPDGTLEYLGRNDFQVKVRGFRIELGEIETRLARCHGVHD 7330 Query: 360 CVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536 VV+ + ++A++ P+ + ++ L+ + +YMIP + ++ P+ N Sbjct: 7331 AVVIAREDSPGDKRLVAYLLAQPDTVLEPADLRQRLSEGVAEYMIPSAFVTLDAFPLTPN 7390 Query: 537 GKV 545 GK+ Sbjct: 7391 GKL 7393 Score = 102 bits (244), Expect = 6e-21 Identities = 60/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD + V G GE+ + G +ARGY+ D RFI +P Sbjct: 6141 VPIGRPIANTQLYILDTLGQPVPLGVAGELHIGGVGVARGYLNRPDLTAERFIPDPFINQ 6200 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LY+TGD L G + Y GR D QVK+RG R++L E++ + P V VV+ Sbjct: 6201 PG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVA 6259 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A++ P ++ +L L +YM+P + ++ P+ NGK+ Sbjct: 6260 REDSPGDTRLVAYLCPQPGVTPDPADLRQQLGQHLAEYMVPGAFVTLDAFPLTPNGKL 6317 Score = 101 bits (241), Expect = 1e-20 Identities = 57/178 (32%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD + G GE+ + G +ARGY+ D RFI +P + Sbjct: 1873 VPIGRPIANTCIYILDAKGQPAPVGVAGEIYIGGAGVARGYLNRPDLTAERFIADPFSDS 1932 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 N A++Y+TGD G L G I Y GR D Q+K+RG R++ E++ + P V +V+ Sbjct: 1933 EN-AQIYKTGDLGRWLPDGNIEYLGRNDFQIKVRGFRIEPGEIEARLMAYPGVREALVIA 1991 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A++ P + + + L L +YM+P + ++ P+ NGK+ Sbjct: 1992 REDSPGDIRLVAYLIAQPGSELIPSVLRKALALHLAEYMVPSAFVTLDAFPLTPNGKL 2049 Score = 100 bits (239), Expect = 3e-20 Identities = 58/176 (32%), Positives = 93/176 (52%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P++N VY+L + V G GE+ + G +ARGY+ D RFI NP Sbjct: 795 IGRPLTNTEVYILGTQGQPVPIGVTGEIYIGGAGVARGYLNRPDLTAERFITNPFVDEQE 854 Query: 204 FAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LY+TGD G G I Y GR D QVK+RG R++L E++ + P + VV+ Sbjct: 855 -ARLYKTGDLGYWRHDGSITYLGRNDFQVKLRGFRLELGEIETLLIQYPGIQEAVVILRE 913 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ P+ + + ++ +L+ L +YMIP + ++ P+ NGK+ Sbjct: 914 DIPGDKRLVAYFQAQPDTQPTPADLRLQLSQRLAEYMIPSAFVALDAFPLTPNGKL 969 Score = 99.5 bits (237), Expect = 4e-20 Identities = 59/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD + V G GE+ + G +ARGY+ D RFI +P + Sbjct: 2932 VPIGRPIANTQLYILDTLGQPVPLGVAGELHIGGVGVARGYLNRPDLTVERFIPDPFSNQ 2991 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LY+TGD L G + Y GR D QVK+RG R++L E++ + P V VV+ Sbjct: 2992 PG-ARLYKTGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVA 3050 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A++ ++ +L L +YM+P + ++ P+ NGK+ Sbjct: 3051 REDSPGDTRLVAYLCPQLGVTPDPADLRQQLGQHLAEYMVPGAFVTLDAFPLTPNGKL 3108 >UniRef50_Q5Z1T0 Cluster: Putative non-ribosomal peptide synthetase; n=1; Nocardia farcinica|Rep: Putative non-ribosomal peptide synthetase - Nocardia farcinica Length = 1701 Score = 110 bits (264), Expect = 2e-23 Identities = 69/182 (37%), Positives = 101/182 (55%), Gaps = 8/182 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIGVP N Y Y+LDE ++ V G GE+ + G LARGY+ + RF+ +P Sbjct: 796 VPIGVPNRNVYTYVLDEALQLVPAGVVGELYLGGDQLARGYLGRPELTAQRFVADPFT-- 853 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LYRTGD + G + + GRAD QVK+RG R++L EV+ AV+T P V +CVV+ Sbjct: 854 PG-ARLYRTGDLVRRNHFGELEFVGRADEQVKVRGFRIELGEVEAAVATHPAVGHCVVVV 912 Query: 375 YGVESSNPEILAFVTINPE----ARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNG 539 + P + A+V + + + + A + L YM+P I +P+ VNG Sbjct: 913 AEDPAVGPMLAAYVVPAADEIAGGEIDLEEVRAHAAAVLPQYMVPSAFAVIPEIPLTVNG 972 Query: 540 KV 545 K+ Sbjct: 973 KL 974 >UniRef50_Q2ANW8 Cluster: Non-ribosomal peptide synthase:Amino acid adenylation; n=1; Bacillus weihenstephanensis KBAB4|Rep: Non-ribosomal peptide synthase:Amino acid adenylation - Bacillus weihenstephanensis KBAB4 Length = 4080 Score = 110 bits (264), Expect = 2e-23 Identities = 61/179 (34%), Positives = 101/179 (56%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197 +P+G P++N +Y+LDENM + G GE+ + G LARGY+ +FI +P+ + Sbjct: 2297 IPVGKPLANRRIYILDENMHPLPIGVKGEIFIGGIPLARGYINNSKLTKDKFIRDPY--Y 2354 Query: 198 PNFAK-LYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 N+ K LY+TGD G +L G I GR D Q KIRGHR+D+ E++ ++ + N +V+ Sbjct: 2355 HNYGKMLYKTGDMGKLLCDGNIEVLGRKDDQTKIRGHRIDIGEIEVVLNKCDNIKNSIVV 2414 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 +++ ++AF + +I L L +YMIP I++ ++P+ NGK+ Sbjct: 2415 VKNGVANDKYLVAFYDSPSNGTNNQCSIRGFLRKKLPEYMIPSYFIQLGSLPLSPNGKI 2473 Score = 100 bits (240), Expect = 2e-20 Identities = 59/179 (32%), Positives = 103/179 (57%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TV +G PISN Y+LD++ G PGE+ +AG + RGY+ + +F+++P N Sbjct: 771 TVSLGRPISNVRCYILDKDKNISPIGVPGELYIAGDGVGRGYLNLPEFTNEKFMNDPFN- 829 Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 PN ++Y+TGD G L G I + GR D QVKIRG+R++L E+ + + +++ V+ Sbjct: 830 -PN-DRMYKTGDLGRWLPNGEIEFLGREDHQVKIRGYRIELSEIHNLILKRNYIEDVAVI 887 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + + I A++ + + M + ++ L L DYM+P I++E++P+ GK+ Sbjct: 888 DWEINNGKKVICAYIVSHVQVNM--EELKGFLAKELPDYMLPSYYIQLESLPLTSIGKL 944 Score = 90.6 bits (215), Expect = 2e-17 Identities = 53/176 (30%), Positives = 95/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+ N +++LD + V G GE+C+ G + GY+ D +FI H Sbjct: 3349 IGKPVDNTKIFILDRGQKLVPLGMAGEICIGGVGVTEGYLNQIDLNSEKFITVSPLGHEK 3408 Query: 204 FAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 KLYRTGD G L + + GR D+Q+KIRG+RV+L+E++ + + + +V+ Sbjct: 3409 I-KLYRTGDLGRLTCHQEVEFLGRIDNQLKIRGYRVELEEINSVLLQHDMILDAIVVPKK 3467 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + +N + A++ + + + I L+S + YM+P + I+++ +P+ NGK+ Sbjct: 3468 DKENNNILCAYIVL--KENENGWGIREYLSSKIPYYMMPSIFIKLDRIPLTPNGKL 3521 >UniRef50_UPI000038CDA7 Cluster: COG1020: Non-ribosomal peptide synthetase modules and related proteins; n=1; Nostoc punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide synthetase modules and related proteins - Nostoc punctiforme PCC 73102 Length = 1075 Score = 109 bits (263), Expect = 3e-23 Identities = 67/184 (36%), Positives = 97/184 (52%), Gaps = 9/184 (4%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVP+G P++N +YLLDE ++ V G PGE+ + G LARGY+ D +FI NP Sbjct: 769 TVPLGRPLANTQIYLLDEQLQPVPVGVPGELYIGGAGLARGYLNQSDLTAAQFIPNPFAD 828 Query: 195 HPNFA-----KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVD 356 A +LY+TGD L G I + GR D QVKIRG R++L E++ + P V Sbjct: 829 TGLIASKPGSRLYKTGDLARYLPDGNIEFLGRVDHQVKIRGFRIELGEIETTLCQHPQVQ 888 Query: 357 NCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLV 533 V E N ++A+V + +S + L L +YM+P I ++ +P+ Sbjct: 889 QAVASIREEEFGNKSLVAYVVPKQQQTLSVSELYRFLREKLPEYMMPATFIMLKALPLTP 948 Query: 534 NGKV 545 NGKV Sbjct: 949 NGKV 952 >UniRef50_Q5YPH7 Cluster: Putative non-ribosomal peptide synthetase; n=2; cellular organisms|Rep: Putative non-ribosomal peptide synthetase - Nocardia farcinica Length = 8426 Score = 109 bits (263), Expect = 3e-23 Identities = 66/180 (36%), Positives = 105/180 (58%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVP+G P+ N Y+LD +R V G PGE+ +AG LARGY+ D RF+ +P + Sbjct: 2581 TVPMGRPVWNTRAYVLDARLRPVPVGVPGELYLAGAQLARGYLGRADLTGDRFVADPFD- 2639 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD ++ G + Y GR D QVK+RG R++L E++ A+ +P V+ VL Sbjct: 2640 EPG-DRMYRTGDLVRWNRDGELEYLGRTDFQVKLRGLRIELGEIETALLAVPGVEQAAVL 2698 Query: 372 CYGVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + P ++A+V + P + A+ + AEL L YM+P V + ++ +P+ +GK+ Sbjct: 2699 VRDDHGTGPRLVAYVVGVEP---VPAEGLRAELARRLPGYMVPGVYVALDALPLNASGKL 2755 Score = 108 bits (259), Expect = 9e-23 Identities = 61/177 (34%), Positives = 99/177 (55%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG P + VY+LD+ + V G GE+ + G LARGY R D RF+ +P P Sbjct: 7887 PIGAPEAGTRVYVLDDRLHPVPTGVVGELYLGGAQLARGYHRRPDLTAERFVADPFGA-P 7945 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +LYRTGD +G +++ R D QVK+RG+R++L E++HA+ P V VVL + Sbjct: 7946 G-ERLYRTGDLVRWTAEGQLVFVQRRDFQVKVRGYRIELTEIEHALRAHPAVAEAVVLAH 8004 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 G + ++ +VT + +++ A L +L YM+P ++ ++ +P+ NGK+ Sbjct: 8005 GAGGAEAMLVGYVT--TRTPVDTEDLRAALAGTLPGYMVPAALVRLDALPLTANGKL 8059 Score = 97.1 bits (231), Expect = 2e-19 Identities = 63/182 (34%), Positives = 92/182 (50%), Gaps = 8/182 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P N+ VY+LD + G PGE+ +AG LARGY D RF+ NP Sbjct: 1512 VPIGEPEWNSQVYVLDARLHPAPIGVPGELYLAGDQLARGYHGRVDLTADRFVANPFGR- 1570 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G ++Y GR D QVK RG R++L E++ A+ P V Sbjct: 1571 -GGERMYRTGDLVRWSSDGELIYLGRVDFQVKFRGQRIELAEIETALLAEPEVGQAAAAL 1629 Query: 375 YGVESSNPE----ILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539 + E + E ++ +V P A + + A LT L YM+P ++E+ P+ +G Sbjct: 1630 WSRERGSGEPGEHLVGYVVAAPGAEVDIDRLRAALTRRLPAYMVPTALVELAEFPLNTSG 1689 Query: 540 KV 545 K+ Sbjct: 1690 KL 1691 Score = 96.7 bits (230), Expect = 3e-19 Identities = 59/178 (33%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P+ N + +LD +R V G PGE+ +AG LA GYV D RF+ +P Sbjct: 4704 VPIGRPVFNTRLLVLDARLRPVPVGVPGELYLAGAQLALGYVARPDLTAERFVADPFGEP 4763 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + ++YRTGD ++ G + Y GR D QVK+RG R++L E++ A++ +P ++ VL Sbjct: 4764 GD--RMYRTGDLVRWNRDGELEYLGRTDFQVKLRGLRIELGEIETALTALPGIEQAAVLV 4821 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 G ++ ++ + + + A + A L + L YM+P + ++ +PV +GK+ Sbjct: 4822 RGTAGGEDTLVGYL-VATDPDLDA--VRAALAARLPAYMVPAAFVVLDELPVNSSGKL 4876 Score = 95.5 bits (227), Expect = 7e-19 Identities = 57/178 (32%), Positives = 91/178 (51%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V +GVP++ +LD +R V G PGE+ + G LARGY G RF+ +PH Sbjct: 6808 VELGVPLAGMSAVVLDARLRPVPAGVPGELYLRGHGLARGYHARPGLTAGRFVADPHG-- 6865 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +LYRTGD G + Y GR D QVK+RG R++L E+D ++ P V V + Sbjct: 6866 PAGGRLYRTGDLACWTADGALRYLGRGDHQVKVRGLRIELGEIDTVLAAHPSVRAAVTVG 6925 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + V + ++++V + + A +L YM+P + + + +P+ GK+ Sbjct: 6926 HAVAGEDVALVSYVVAAQGEIVDTAALLAHAARALPPYMVPAAVTVLDRLPLTPVGKL 6983 Score = 94.7 bits (225), Expect = 1e-18 Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V IG P N VY+LD +R V G PGE+ +AG LARGY R G RF+ +P Sbjct: 3648 VAIGRPCWNTRVYVLDTRLRPVPIGVPGELYLAGNQLARGYHRRPGPTAERFVADPFGV- 3706 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P + +YRTGD ++ G ++Y GR D QVK+RG R++L E++ A++ +P V N V Sbjct: 3707 PG-SLMYRTGDLVRWNRDGDLIYLGRNDFQVKLRGQRIELGEIEAALAAVPGVANAAVRV 3765 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++ +V+ + +SA + L L YM+P ++ + +P+ GK+ Sbjct: 3766 VADSAGRDALVGYVSGDD---LSAAAVLDVLRDRLPGYMVPAHLVVLAEMPLTTVGKL 3820 Score = 90.2 bits (214), Expect = 3e-17 Identities = 64/185 (34%), Positives = 97/185 (52%), Gaps = 9/185 (4%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHN 191 +TVPIG +N + +LDE++R V G GE+ +AG LARGYV G RF+ NPH Sbjct: 441 VTVPIGTVADDNELLVLDESLRPVPTGVVGELYLAGVQLARGYVARPGLTAERFVANPHG 500 Query: 192 THPNFAKLYRTGDF----GILDKG--VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353 P ++YRTGD G D G + Y GR D QVK+RG R++L EV+ A+ V Sbjct: 501 A-PG-ERMYRTGDLVRWGGGADGGPLELEYLGRIDFQVKLRGLRIELGEVEAALLRSQQV 558 Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVL 530 V+ + + + L + + + A L +YM+P ++++ + +PV Sbjct: 559 AQAAVVVR--QHAGGDHLVGYVVPAGGPVDPAAVLAVAREHLPEYMVPALVQVLDELPVN 616 Query: 531 VNGKV 545 NGK+ Sbjct: 617 ANGKL 621 Score = 80.2 bits (189), Expect = 3e-14 Identities = 58/185 (31%), Positives = 91/185 (49%), Gaps = 12/185 (6%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHNTH 197 PIG P N+ VY+LD +R G GE+ +AG LARGY G+ RF+ NP Sbjct: 5760 PIGNPEWNSRVYVLDSRLRPTLPGVAGELYLAGVQLARGY-HGRPALTADRFVANPFGAA 5818 Query: 198 PNFAKLYRTGDFGIL----DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 ++YRTGD D ++Y GR D QVK RG R++L E++ ++ +P V Sbjct: 5819 GE--RMYRTGDLVRWETRGDTAELVYLGRTDFQVKFRGQRIELGEIEAVLAAVPGVAGAA 5876 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNI----EAELTSSLTDYMIP-QVIEIETVPVL 530 G ++ ++ + PEA + A +L YM+P ++ ++ P+ Sbjct: 5877 ARVLG-----EHLVGYLLVAPEAADDHDAVLARARAAAHEALPAYMVPGALLALDEFPLN 5931 Query: 531 VNGKV 545 V+GK+ Sbjct: 5932 VSGKL 5936 >UniRef50_Q3M3K1 Cluster: Amino acid adenylation precursor; n=2; Nostocaceae|Rep: Amino acid adenylation precursor - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 1436 Score = 109 bits (263), Expect = 3e-23 Identities = 65/178 (36%), Positives = 101/178 (56%), Gaps = 6/178 (3%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH--NTH 197 IG PI+N +Y+LD+ ++ V G PGEV ++G +A+GY R D RFI +P NTH Sbjct: 863 IGQPIANTQIYILDQLLQPVPVGAPGEVYISGVGVAKGYFRRTDLTSERFIPHPFSDNTH 922 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LY+TGD L G I Y GR D+QVKI G VDL++++ + + VV+ Sbjct: 923 E---RLYKTGDLARYLPDGNIEYLGRTDNQVKICGVCVDLEQIEALLHQHQAITQAVVIA 979 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 V S +++A++ PE + +++ L+ + Y IP I +E++PV NG+V Sbjct: 980 TEVTSGEKQLVAYLVTQPEQTPTIDDLQTFLSQKIPHYWIPSDFIFLESLPVNTNGQV 1037 >UniRef50_Q1RS73 Cluster: NRPS/PKS protein; n=5; Bacteria|Rep: NRPS/PKS protein - Bacillus amyloliquefaciens Length = 4982 Score = 109 bits (263), Expect = 3e-23 Identities = 66/175 (37%), Positives = 95/175 (54%), Gaps = 3/175 (1%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFA 209 IG PI+N VY++D + V EG PGE+C+AG LARGY + H + Sbjct: 1452 IGRPIANTRVYIMDSGLNPVLEGVPGELCIAGDGLARGYFNKPELTDKAFVSHRLELG-S 1510 Query: 210 KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVE 386 KLY+TGD L G I Y GR D+QVKIRG+R++ +++ ++ P V VV+ Sbjct: 1511 KLYKTGDMARFLPGGRIEYMGRMDTQVKIRGYRIEPGDIESRLNAHPAVQESVVVVNN-H 1569 Query: 387 SSNPEILAF-VTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 S N ++ AF + N E SAK + + +L YM P + +E +P+ NGKV Sbjct: 1570 SGNEKLCAFYIRKNGEPLPSAKELRKHMKQALPAYMAPASFVRLEELPLTPNGKV 1624 Score = 52.0 bits (119), Expect = 9e-06 Identities = 48/185 (25%), Positives = 79/185 (42%), Gaps = 11/185 (5%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 V IG+PI + + D+ + V EGE G V+G + GY D + + Sbjct: 374 VEIGLPIPGFNMRITDDRNQVVEEGEIGRFQVSGLTVTSGYYERPDLNESVFTEDG---- 429 Query: 204 FAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGV 383 + TGD G L +G + GR + I G ++ AV +P ++ V Sbjct: 430 ---WFETGDLGFLREGRLTITGRTKDAIIINGVNYYSHAIESAVEELPEIETSYTAACAV 486 Query: 384 ---ESSNPEI-LAFVTINP--EARMS--AKNIEAELTSSL---TDYMIPQVIEIETVPVL 530 +S+ E+ + FVT P E RM+ +I +T + DY++P + E +P Sbjct: 487 RPNQSTTDELAIFFVTSVPLDENRMTKLLHHIHQHVTQRIGVTPDYLLP--VAKEDIPKT 544 Query: 531 VNGKV 545 GK+ Sbjct: 545 AIGKI 549 >UniRef50_Q0LLT6 Cluster: Amino acid adenylation; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Amino acid adenylation - Herpetosiphon aurantiacus ATCC 23779 Length = 2844 Score = 109 bits (263), Expect = 3e-23 Identities = 64/178 (35%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI+N +Y+LD ++ V G GE+ + G + RGY R D RF+ +P Sbjct: 2298 LPIGRPIANTQMYVLDPRLQLVPIGVVGELYIGGAGVGRGYHRRPDLTAERFVPDPFGGQ 2357 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LY+TGD G IL G + GR D QVK+RG R++L+E++ A+ V VV Sbjct: 2358 PG-ARLYKTGDLGRILADGTLECLGRVDHQVKVRGFRIELEEIEAALLRQAGVREAVVAA 2416 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ES + ++ A+V P+ + ++ L L YM P ++ I+ +P+ NGKV Sbjct: 2417 RRQESGDIQLAAYVVAAPDNPLQIPTLKQSLQELLPAYMAPSHIMLIDELPLTSNGKV 2474 Score = 90.6 bits (215), Expect = 2e-17 Identities = 54/179 (30%), Positives = 93/179 (51%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 + P+G P+ V LLD+ R V G GE+ + G ++RGY R++ +P + Sbjct: 1231 SAPLGAPLEATQVALLDDQGRVVPVGIAGELYLGGAGVSRGYFGRPALTAERYLPDPFSG 1290 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A++YRTGD + G++ Y GR + QVK+RG R++L EV+ A+S V V+ Sbjct: 1291 VLG-ARMYRTGDRALYRADGMLEYRGRVEQQVKLRGFRIELGEVEAALSEQAAVQEAAVV 1349 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +P ++ +V + + ++A L L +YM+P QV+ + +P +GK+ Sbjct: 1350 IKASPRGDPTLVGYVVARAGEALDSTTVQAALRERLPEYMVPSQVVVLLGLPRTSSGKL 1408 Score = 83.4 bits (197), Expect = 3e-15 Identities = 54/177 (30%), Positives = 90/177 (50%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200 P+G I N+ Y+LD + V G GE+ + G ++RGY R++ +P + Sbjct: 167 PLGRTIDNSEGYVLDGFQQPVPVGIAGELYLGGAGVSRGYFGRPALTAERYLPDPFSGVL 226 Query: 201 NFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A++YRTGD G + Y GR D QVK+RG R++L EV+ A+S V V+ Sbjct: 227 G-ARMYRTGDRVRRQADGTLEYLGRMDRQVKLRGFRIELGEVEAALSEQAAVQEAAVVIK 285 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +P ++ +V + + ++A L L +YM+P QV+ + +P +GK+ Sbjct: 286 ASPRGDPTLVGYVVARAGEALDSTTVQAALRERLPEYMVPSQVVVLLGLPRTSSGKL 342 >UniRef50_A3DGP7 Cluster: Amino acid adenylation domain; n=1; Clostridium thermocellum ATCC 27405|Rep: Amino acid adenylation domain - Clostridium thermocellum (strain ATCC 27405 / DSM 1237) Length = 625 Score = 109 bits (263), Expect = 3e-23 Identities = 66/179 (36%), Positives = 103/179 (57%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHNT 194 VPIG PI N Y+LDE+++ V GE GE+ + G + RGY GK ++I NP + Sbjct: 332 VPIGYPIDNTQAYILDEDLKPVPFGEVGELYIGGDGVGRGYF-GKPELTSEKYIQNPFSD 390 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + + ++ +TGD L G I Y GRAD Q+K+RG R++L E++ A+ P V VV+ Sbjct: 391 NQS-DRICKTGDLARFLPDGSIEYLGRADFQIKLRGFRIELGEIESAIEKHPWVQQAVVV 449 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E + I+A+ E S++++ + L ++L DYMIP ++I+ P+ NGKV Sbjct: 450 KDNGE-GDQHIVAYFRTKSEQVPSSEDMRSFLKNTLPDYMIPSFFVQIDEFPLTPNGKV 507 >UniRef50_Q3M1N0 Cluster: Amino acid adenylation; n=2; Bacteria|Rep: Amino acid adenylation - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 2867 Score = 109 bits (262), Expect = 4e-23 Identities = 63/176 (35%), Positives = 96/176 (54%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI + VY+LD++ + V G GE+ + G LA+GY+ D +FI +P + P+ Sbjct: 824 IGRPIPDLQVYILDQHQQLVPIGVSGEMYIGGGGLAKGYLNRPDLTTEKFIPHPFSNQPD 883 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LY++GD L G I Y GR D QVKIRG R++L E+ ++ P V VVL Sbjct: 884 -ARLYKSGDLARYLPNGDIEYLGRIDHQVKIRGFRIELGEIAGILTQHPSVQETVVLAKE 942 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 S ++A+V + + + L L DYM+P V + +E +P+ NGK+ Sbjct: 943 TSSGEKYLVAYVVFRHQQTPTTSQLRNFLKKQLPDYMLPSVFVVVEALPLTANGKL 998 Score = 79.0 bits (186), Expect = 7e-14 Identities = 46/142 (32%), Positives = 81/142 (57%), Gaps = 4/142 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPH 188 +++PIG PI N +Y+L+ + + V G GE+ + G +ARGY+ GK +FI + Sbjct: 1892 ISIPIGRPIHNTQIYILNSDGKLVPVGVTGELYIGGDGIARGYL-GKPQLTAEKFIPDFF 1950 Query: 189 NTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 + P A+LY+TGD G I + GR+D QVKIRG R++L E++ + P + Sbjct: 1951 SDEPG-ARLYKTGDLARYRPDGNIEFLGRSDRQVKIRGFRIELGEIEAVLEQHPTIREVA 2009 Query: 366 VLCYGVESSNPEILAFVTINPE 431 V+ ++ + ++A++ +P+ Sbjct: 2010 VVSREIQ-GDLRLVAYIVPSPQ 2030 >UniRef50_Q2SKF9 Cluster: Non-ribosomal peptide synthetase modules and related protein; n=1; Hahella chejuensis KCTC 2396|Rep: Non-ribosomal peptide synthetase modules and related protein - Hahella chejuensis (strain KCTC 2396) Length = 1756 Score = 109 bits (262), Expect = 4e-23 Identities = 65/178 (36%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNTH 197 V IG PI N ++++D+ +R + G PGE+C+AG LARGY + RF+ NP N Sbjct: 582 VTIGSPIDNTQIHIVDKQLRRLPIGVPGELCIAGVGLARGYHALPEVTADRFVANPENAS 641 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + YRTGD L G I Y GR D QVK+RG R++LQE+D + + V + V L Sbjct: 642 ERW---YRTGDLARWLGNGEIEYLGRLDHQVKVRGFRIELQEIDAVLRSHSAVRDAVTLV 698 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + +++A+VT N E + + + + YM+P VI +E +P+ NGK+ Sbjct: 699 HRAAGLD-KLVAYVTANGEP--EPETLRQHVAGQVPAYMVPDMVIVLEQMPLSPNGKL 753 >UniRef50_Q04747 Cluster: Surfactin synthetase subunit 2; n=9; Bacillus|Rep: Surfactin synthetase subunit 2 - Bacillus subtilis Length = 3587 Score = 109 bits (262), Expect = 4e-23 Identities = 63/179 (35%), Positives = 102/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++PIG PI N+ Y++DE G PGE+CV G +ARGYV + +F+ +P Sbjct: 773 SIPIGKPIGNSTAYIMDEQQCLQPIGAPGELCVGGIGVARGYVNLPELTEKQFLEDPF-- 830 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD L G I + GR D+QVK+RG R++L E++ ++ V V+ Sbjct: 831 RPG-ERIYRTGDLARWLPDGNIEFLGRIDNQVKVRGFRIELGEIETKLNMAEHVTEAAVI 889 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ EI A+ T + E +S + L+ SL DYM+P +I+++++P+ NGK+ Sbjct: 890 IRKNKADENEICAYFTADREVAVS--ELRKTLSQSLPDYMVPAHLIQMDSLPLTPNGKI 946 Score = 104 bits (250), Expect = 1e-21 Identities = 67/178 (37%), Positives = 100/178 (56%), Gaps = 3/178 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194 ++ IG I+N VY+L E + EG GE+CVAG LARGY+ +D RF+ +P Sbjct: 2848 SLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAKRFVADPFV- 2906 Query: 195 HPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD G I Y GR D QVK+RG+R++L E++ ++ + V++ V Sbjct: 2907 -PG-ERMYRTGDLVKWVNGGIEYIGRIDQQVKVRGYRIELSEIEVQLAQLSEVEDRAVTR 2964 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + N I A+VT PE + +++ L +L DYMIP + + +PV NGKV Sbjct: 2965 VKDKGGNTAIAAYVT--PET-ADIEALKSTLKETLPDYMIPAFWVTLNELPVTANGKV 3019 Score = 93.5 bits (222), Expect = 3e-18 Identities = 56/175 (32%), Positives = 98/175 (56%), Gaps = 4/175 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+N +L+E ++ V G G++ + G LARGY+ RF+ NP++ P Sbjct: 1821 IGRPIANAGALVLNEALKLVPPGASGQLYITGQGLARGYLNRPQLTAERFVENPYS--PG 1878 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 + +Y+TGD L G + + GRAD QVKIRG+R++L E++ + ++ + VVL Sbjct: 1879 -SLMYKTGDVVRRLSDGTLAFIGRADDQVKIRGYRIELGEIETVMLSLSGIQEAVVLAVS 1937 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542 E E+ A+ T + + + + +L+ +L +MIP ++++ +P+ NGK Sbjct: 1938 -EGGLQELCAYYTSDQD--IEKAELRYQLSLTLPSHMIPAFFVQVDAIPLTANGK 1989 >UniRef50_O68008 Cluster: Bacitracin synthetase 3 (BA3) [Includes: ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); ATP-dependent histidine adenylase (HisA) (Histidine activase); ATP-dependent D-aspartate adenylase (D-AspA) (D-aspartate activase); ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); Aspartate racemase (EC 5.1.1.13); Phenylalanine racemase [ATP hydrolyzing] (EC 5.1.1.11)]; n=3; Bacillus|Rep: Bacitracin synthetase 3 (BA3) [Includes: ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); ATP-dependent histidine adenylase (HisA) (Histidine activase); ATP-dependent D-aspartate adenylase (D-AspA) (D-aspartate activase); ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); Aspartate racemase (EC 5.1.1.13); Phenylalanine racemase [ATP hydrolyzing] (EC 5.1.1.11)] - Bacillus licheniformis Length = 6359 Score = 109 bits (262), Expect = 4e-23 Identities = 65/179 (36%), Positives = 103/179 (57%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+PIG P++N V ++DE + + G PGE+C+AG L++GY+ ++ +FI PH Sbjct: 768 TIPIGSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFI--PHPF 825 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +LY+TGD L G I + GR D QVKIRG R++L E++ + ++ +V Sbjct: 826 IPG-ERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVT 884 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E S P I A++T N E +S ++ L L +YMIP ++++ +P+ NGKV Sbjct: 885 VREDEESRPYICAYITANRE--ISLDELKGFLGEKLPEYMIPAYFVKMDKLPLTKNGKV 941 Score = 109 bits (262), Expect = 4e-23 Identities = 63/176 (35%), Positives = 95/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI N Y+LDENM+ + EG GE+C+AG + GYV D +FI NP H Sbjct: 4351 IGTPIHNTNAYVLDENMKLLPEGVYGELCIAGAGVTGGYVNRPDETKEKFIENPFAPH-- 4408 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 K+YRTGD L G I AGR D+QVK+RG+R++ +E+ + + + + Sbjct: 4409 -TKMYRTGDLARRLSDGNIELAGRIDTQVKVRGYRIEPEEIKNRLLAHDDIKEAFIAARE 4467 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ A+ T +A + ++I L L +YMIP ++IE +P+ NGK+ Sbjct: 4468 DHKGAKQLCAYFT--ADAELPFEDIRTYLMHELPEYMIPSSFVQIEKMPLSANGKI 4521 Score = 108 bits (260), Expect = 7e-23 Identities = 63/178 (35%), Positives = 101/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V IG PISN+ VY+L+ N + + G PGE+C++G LARGY+ D +F+ NP Sbjct: 3306 VVIGRPISNHKVYILNHNQQLLPLGTPGELCLSGEGLARGYLNRPDLTLEKFVPNPF--A 3363 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +YRTGD L G I Y GR D QVKIRG R++L E+++ + I +D V+ Sbjct: 3364 PG-ESMYRTGDLARFLPDGQIEYLGRIDHQVKIRGFRIELGEIENQLLKIEGIDAAAVMA 3422 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++ + A++ + A ++ ++ L L DYM+P ++++ +P+ NGK+ Sbjct: 3423 REDQAGGKYLCAYIVADKAAGVA--DVRKCLLKELPDYMVPSYFVKLDQLPLTANGKI 3478 Score = 98.7 bits (235), Expect = 8e-20 Identities = 59/176 (33%), Positives = 96/176 (54%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+N VY+LD+N + V G GE+CV G +LARGY+ + +FI +P + Sbjct: 1803 IGSPIANTNVYVLDQNQKPVPTGVVGELCVGGMSLARGYLNRPELTAEKFISHP---FAS 1859 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LYRTGD L G + + GR D QVKIRG+R++L E+++ + + +D V+ Sbjct: 1860 GERLYRTGDLARWLPDGHLEFLGRIDHQVKIRGYRIELGEIENQLLKLDKIDEAAVIARK 1919 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + + A++ + ++ I L L YMIP + ++ +P+ N KV Sbjct: 1920 DDDHSDYLCAYIVSKED--WTSTEISEWLEKELPHYMIPAYFVRLDKLPLTSNDKV 1973 Score = 98.3 bits (234), Expect = 1e-19 Identities = 59/180 (32%), Positives = 101/180 (56%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 ++VPIG P SN +Y+LDE G GE+ ++G +A+GY+ + +F+ NP Sbjct: 5853 VSVPIGKPASNVQLYILDERQEVQPVGIAGELYISGDGVAKGYLNKPELTSEKFLPNPF- 5911 Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 P ++YRTGD + G I Y GR D QVKIRG+R++L E++H + + V Sbjct: 5912 -LPG-ERMYRTGDLAKMRPDGHIEYLGRIDHQVKIRGYRIELGEIEHQLLRHSDIKEAAV 5969 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + +N ++L ++ E ++ K+I+ L L +YM+P +++++ +P+ NGKV Sbjct: 5970 AA-KTDQNNDQVLCAYVVS-ERDITQKDIKTFLAKELPEYMVPSYLLKLDELPLTPNGKV 6027 >UniRef50_Q84DH9 Cluster: Peptide synthase; n=3; Streptomyces|Rep: Peptide synthase - Streptomyces ansochromogenes Length = 677 Score = 109 bits (261), Expect = 5e-23 Identities = 65/179 (36%), Positives = 98/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PI N Y+LD+ +R V GEPGE+ + G +A GY+ RF+ +P + Sbjct: 395 SVPIGRPIDNVRTYVLDDALRPVPAGEPGELFIGGAGVAVGYLNAPQTTAERFLPDPFSG 454 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++LYRTGD D G + + GR D QVK+RG+R++L E++ ++ V CV L Sbjct: 455 VPG-SRLYRTGDLVRADADGCLEFLGRRDHQVKLRGYRIELGEIEAVLTEHEDVRACVAL 513 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 G + + ++ FVT A A + A L L YMIP + + + P+ NGK+ Sbjct: 514 VTG-DGPDSALVCFVTAGGRAAPPAAELIAHLRGRLPWYMIPTAVHVLDAFPLTPNGKI 571 >UniRef50_Q1RS70 Cluster: Hybrid NRPS/PKS; n=4; cellular organisms|Rep: Hybrid NRPS/PKS - Bacillus amyloliquefaciens Length = 5433 Score = 109 bits (261), Expect = 5e-23 Identities = 70/178 (39%), Positives = 99/178 (55%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI N +Y++DE + V +G GE+CVAG LARGY + FI NP + Sbjct: 807 PIGKPIHNTRLYIVDEKLSPVPDGVAGELCVAGAGLARGYYNQPELTAASFIDNPFS--- 863 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP-CVDNCVVLC 374 KLY+TGD L G I YAGR DSQVKIRG R++L ++ +S P +D VV+ Sbjct: 864 EGEKLYKTGDLARWLPDGNIEYAGRIDSQVKIRGFRIELGAIETKLSEHPDILDQAVVV- 922 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ + +++A+ T K + L SSL DYM P I ++ +P+ +GKV Sbjct: 923 -QEKNGHKKLIAYYTARSGHTADEKALRNHLLSSLPDYMAPAHFIRLDALPLTPSGKV 979 >UniRef50_A0ZL90 Cluster: Non-ribosomal peptide synthase; n=1; Nodularia spumigena CCY 9414|Rep: Non-ribosomal peptide synthase - Nodularia spumigena CCY 9414 Length = 1518 Score = 109 bits (261), Expect = 5e-23 Identities = 58/180 (32%), Positives = 103/180 (57%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 + + IG I++ +Y+LD ++ V G PGE+ +AG LARGY+ D +FI NP + Sbjct: 766 MKISIGQAIAHTQIYILDHYLQPVPIGVPGELHIAGVGLARGYLNQPDLTAQKFIPNPFS 825 Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 N ++LY+TGD G L G I + GR D+QVKIRG R++L+E++ + P + + Sbjct: 826 NDTN-SRLYKTGDLGRYLPDGNIEFLGRIDNQVKIRGFRIELEEIETTIVQHPQIQQAIA 884 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A++ + + +++ I L L +YMIP + + ++++P+ NGK+ Sbjct: 885 IVREDIPGTKRLVAYIVPHQQHSLNSNEIWEYLKHKLPEYMIPAIFVFLDSLPLTPNGKI 944 >UniRef50_Q8GN23 Cluster: Peptide synthetase; n=1; Fischerella sp. CENA19|Rep: Peptide synthetase - Fischerella sp. CENA19 Length = 582 Score = 108 bits (260), Expect = 7e-23 Identities = 66/185 (35%), Positives = 102/185 (55%), Gaps = 10/185 (5%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNP--- 185 TV IG P++N +Y+LDE M+ + G PGE+CV+G + GY + ++ F+ NP Sbjct: 268 TVSIGKPLANLNLYILDEQMQLLPIGVPGEICVSGIGVGEGYWKNEEKTNLSFVPNPFAD 327 Query: 186 -HNTHPNFAK--LYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353 P + +Y+TGD G L G I + GR D QVKIRG RV+L EV+ +S P V Sbjct: 328 ARKKLPENRRDLIYKTGDLGRWLPDGNIEFLGRIDHQVKIRGFRVELGEVETFLSQHPNV 387 Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVL 530 +V+ + E N +++A+V E S + L L D+M+P + +E++P+ Sbjct: 388 RENIVIVHQEEPGNLQLVAYVVAKTEPVPSISELRNFLKEKLPDHMLPSTFVMLESLPIA 447 Query: 531 VNGKV 545 +GKV Sbjct: 448 PSGKV 452 >UniRef50_Q84BC7 Cluster: NcpB; n=3; Cyanobacteria|Rep: NcpB - Nostoc sp. ATCC 53789 Length = 4803 Score = 108 bits (260), Expect = 7e-23 Identities = 69/201 (34%), Positives = 105/201 (52%), Gaps = 26/201 (12%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVPIG PISN +Y+LD+N++ V G PGE+ + G LA+GY+ + +FI NP + Sbjct: 1894 TVPIGRPISNTQIYILDQNLQPVPVGVPGELHIGGAGLAKGYLNRPELTQEKFIPNPFSG 1953 Query: 195 HPNFA----------------------KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHR 305 +LY+TGD L G I Y GR D+QVKIRG R Sbjct: 1954 SRRAGEQRSRGAGERRRKIVQSPVASPRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFR 2013 Query: 306 VDLQEVDHAVSTIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTD 485 ++L E++ A+S V VV+ + +++++ + PE + K + + L L D Sbjct: 2014 IELGEIEAALSQHKDVQTSVVIVREDIPGDKRLVSYIVLQPEQTTTVKELRSFLKEKLPD 2073 Query: 486 YMIPQVIEI-ETVPVLVNGKV 545 YM+P I I E++P+ NGK+ Sbjct: 2074 YMVPSAIAILESLPLTSNGKI 2094 Score = 99 bits (238), Expect = 3e-20 Identities = 72/207 (34%), Positives = 106/207 (51%), Gaps = 31/207 (14%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV---------------- 149 L PIG PISN +Y+LD+ ++ V G PGEV +AG LARGY+ Sbjct: 3021 LLPPIGRPISNTQIYILDKYLQPVPIGVPGEVYIAGVLLARGYLNRPELTQEKFIQNPFG 3080 Query: 150 ----------RGKDPHRFIHNPHNTHPNFA--KLYRTGDFG-ILDKGVILYAGRADSQVK 290 RG + F PH+ P+ + +LY+TGD L G I Y GR D+QVK Sbjct: 3081 GSRGAGEQGSRGAEEQSFPSAPHSLCPSASSERLYKTGDLARYLPDGNIEYLGRIDNQVK 3140 Query: 291 IRGHRVDLQEVDHAVST-IPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAEL 467 IRG R++L E++ +S I +C V+ + ++A++ PE R+S + + L Sbjct: 3141 IRGFRIELGEIEAVLSQHINVQASCAVVREDT-PGDKRLVAYIVPQPEQRVSVNVVRSFL 3199 Query: 468 TSSLTDYMIPQVIEI-ETVPVLVNGKV 545 L +YM+P I I E +P+ NGK+ Sbjct: 3200 KEKLPEYMLPSAIVILEALPITSNGKL 3226 Score = 94.7 bits (225), Expect = 1e-18 Identities = 66/197 (33%), Positives = 99/197 (50%), Gaps = 22/197 (11%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP--- 185 T+PIG PISN +YLLD ++ V G PGE+ + G LAR Y+ + + I NP Sbjct: 801 TIPIGQPISNTQIYLLDSQLQPVGIGVPGELYIGGDGLAREYLNRTELTQEKLIQNPFGG 860 Query: 186 -------------HNTHPNFA--KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQ 317 + P+ + +LY+TGD L G I Y GR D QVKIRG R++L Sbjct: 861 SRGAGEQGSKGAEEQSFPSASSERLYKTGDKARYLSDGNIEYLGRIDDQVKIRGLRIELG 920 Query: 318 EVDHAVSTIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP 497 E++ +S V V+ + ++A++ + + + + I L + L DYMIP Sbjct: 921 EIEAVLSQHSDVQVSCVIVREDTPGDKRLVAYIVTHQDCQPTMGEIRQFLKAKLPDYMIP 980 Query: 498 QVIEI-ETVPVLVNGKV 545 I I E+ P+ NGK+ Sbjct: 981 SAIVILESFPLTPNGKI 997 Score = 87.4 bits (207), Expect = 2e-16 Identities = 62/198 (31%), Positives = 95/198 (47%), Gaps = 24/198 (12%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH--- 188 + IG ++N VY+LDEN++ V G PGE+ + G LARGY+ + +FI NP Sbjct: 4104 ISIGKAVANTQVYILDENLQLVPVGVPGELHIGGAGLARGYLNRPELTQEKFIPNPFAGS 4163 Query: 189 -----------NTHPNFA------KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDL 314 PN +LY+TGD L G I Y GR D+Q+KIRG R+++ Sbjct: 4164 RGAGEQGSKGAEILPNSQSPVPSPRLYKTGDLARYLPDGNIEYLGRIDNQIKIRGFRIEV 4223 Query: 315 QEVDHAVSTIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMI 494 E++ +S P V VV+ ++ + E + ++ L L YM+ Sbjct: 4224 GEIEAILSQHPGVRENVVVAREDIPGEKRLVVYFVPQLEQTPTTDDLRIFLKEKLPQYMV 4283 Query: 495 PQV-IEIETVPVLVNGKV 545 P + +E +P+ NGKV Sbjct: 4284 PSAFVRLEFLPLTPNGKV 4301 >UniRef50_Q333U8 Cluster: NRPS protein; n=1; Micromonospora sp. ML1|Rep: NRPS protein - Micromonospora sp. ML1 Length = 2594 Score = 108 bits (260), Expect = 7e-23 Identities = 62/177 (35%), Positives = 98/177 (55%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG PI+N V +LD +R V G G++ +AG LARGY R G RF+ NP P Sbjct: 2315 IGTPIANTQVLILDSALRPVPPGVGGDLWIAGDGLARGYHRQPGLTASRFVANPFG--PQ 2372 Query: 204 FAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD + G I + GRAD Q+K+RG R++ +V+HA++ P V VV Sbjct: 2373 GARMYRTGDLARWSESGRIEFLGRADFQIKLRGFRIEPGDVEHALTRHPAVREAVVTIRE 2432 Query: 381 VESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + ++ +V + +A + ++ + L DYM+P V+ + +P+ NGK+ Sbjct: 2433 DQPDDKRLVGYVVVAEDAETPPTRELQQFVREQLPDYMVPSAVVTLPAIPLTANGKL 2489 Score = 81.4 bits (192), Expect = 1e-14 Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 5/158 (3%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 TVP+G PISN VY+LD ++ G GEV V G LARGY+ F+ P Sbjct: 782 TVPLGRPISNAGVYVLDSQLQLTPPGVVGEVYVTGVGLARGYLHRPAATADHFVACPFG- 840 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD D G + +AG AD +V+IRG E++ ++ P VD V+ Sbjct: 841 -PAGTRMYRTGDLARWTDDGELEHAGSADQRVRIRGFWAAFLEIEAVLTAHPGVDQAAVI 899 Query: 372 CY--GVESSNPEILAFVTINPEARMSAKNIEAELTSSL 479 G + + +++A+V RM A ++ + ++ L Sbjct: 900 ARPDGPDRA-AQLIAYVVPATGGRMGAAGLDVDFSAGL 936 >UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Amino acid adenylation - Herpetosiphon aurantiacus ATCC 23779 Length = 2419 Score = 108 bits (260), Expect = 7e-23 Identities = 62/180 (34%), Positives = 98/180 (54%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHN 191 + VPIG +N+ +Y+LD +R V G GE+CVAG +L++GY+ +F+ NP Sbjct: 2130 VNVPIGRVTANHQLYILDAQLRPVPIGVVGELCVAGPSLSQGYLNQPALSAEKFVPNPFA 2189 Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 P +LYRTGD L G+I + GR D QVK+RG+R++L E++ A+ P V VV Sbjct: 2190 AQPG-QRLYRTGDVARYLPDGLIEHLGRIDHQVKVRGYRIELGEIEAALLNHPAVQEAVV 2248 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 L +S ++ +V + + L L YM+P + + +E++P NGK+ Sbjct: 2249 L----PTSEASLIGYVVLKQAGSTPTSELREFLQQRLPGYMLPAILVPLESLPRTANGKI 2304 Score = 93.1 bits (221), Expect = 4e-18 Identities = 51/146 (34%), Positives = 82/146 (56%), Gaps = 3/146 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VP+G PI+N+YVY+LD + V G GE+ + G +ARGY+ + RF+ + +T+ Sbjct: 749 VPLGRPIANSYVYVLDAARQLVPFGAIGELYIGGAGVARGYLNRPELTNERFVTDRLSTN 808 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+ +LYR+GD G++ + GR+D QVKIRG+RV+L E+ H + P V V Sbjct: 809 PS-DRLYRSGDVVRYRPDGLLEFLGRSDDQVKIRGYRVELGEISHTLERHPLVQQSTVQL 867 Query: 375 YGVESSNPEILAFVTINPEARMSAKN 452 S +++ ++ NP + N Sbjct: 868 REHASGEQQLVGYIVPNPALALPVSN 893 >UniRef50_A3IZW4 Cluster: Non-ribosomal peptide synthase; n=2; Cyanothece sp. CCY 0110|Rep: Non-ribosomal peptide synthase - Cyanothece sp. CCY 0110 Length = 1294 Score = 108 bits (260), Expect = 7e-23 Identities = 66/180 (36%), Positives = 101/180 (56%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++ IG PI+N +Y+LD N++ V G PGE+ + G LARGY+ D +FI NP T Sbjct: 1036 SILIGRPINNTQIYILDPNLQPVPVGVPGELHIGGDGLARGYLNRPDLTAEKFIPNPFGT 1095 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 KLY+TGD + G I Y GR D QVKIRG R++L E++ +S P + VV+ Sbjct: 1096 ----GKLYKTGDLCRYRRDGNIEYIGRIDHQVKIRGFRIELGEIETQLSNHPEIRESVVI 1151 Query: 372 CYGVESSNPEILAFVTINPEARMS-AKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 N +++A++ + ++ S + + L L DYMIP + +E +P+ NGK+ Sbjct: 1152 AREDAPGNKQLVAYLVSDEMSQSSVTQTLRDCLKEQLPDYMIPSAFVLLEKLPLTPNGKI 1211 >UniRef50_A0PTU8 Cluster: Non-ribosomal peptide synthetase MbtE; n=1; Mycobacterium ulcerans Agy99|Rep: Non-ribosomal peptide synthetase MbtE - Mycobacterium ulcerans (strain Agy99) Length = 1670 Score = 108 bits (260), Expect = 7e-23 Identities = 67/178 (37%), Positives = 103/178 (57%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIGVP N Y Y+LDE + V + GE+ + G LARGY+ RFI +P N Sbjct: 794 VPIGVPNRNVYAYVLDEQLHPVPDQVVGELYLGGSQLARGYLGRPTLTAQRFIADPFN-- 851 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +LYRTGD + G + + GRAD QVKIRG R++L EV+ ++T P V +C+V+ Sbjct: 852 PGM-RLYRTGDLVRRNHCGELEFVGRADEQVKIRGFRIELGEVESVITTHPAVRHCLVVA 910 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 E + P + A++ + A++ + I A +++ +YM+P I +P+ V+GK+ Sbjct: 911 EETE-AGPMLAAYL-VPAAAQVDLEEIRAHTAAAVPEYMVPGAFAVIPEIPMTVSGKL 966 >UniRef50_O30409 Cluster: Tyrocidine synthetase 3 (Tyrocidine synthetase III) [Includes: ATP- dependent asparagine adenylase (AsnA) (Asparagine activase); ATP- dependent glutamine adenylase (GlnA) (Glutamine activase); ATP- dependent tyrosine adenylase (TyrA) (Tyrosine activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)]; n=8; cellular organisms|Rep: Tyrocidine synthetase 3 (Tyrocidine synthetase III) [Includes: ATP- dependent asparagine adenylase (AsnA) (Asparagine activase); ATP- dependent glutamine adenylase (GlnA) (Glutamine activase); ATP- dependent tyrosine adenylase (TyrA) (Tyrosine activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)] - Brevibacillus parabrevis Length = 6486 Score = 108 bits (260), Expect = 7e-23 Identities = 66/185 (35%), Positives = 98/185 (52%), Gaps = 4/185 (2%) Frame = +3 Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFI 176 + H +PIG PI+N+ Y++D N + G PGE+CV G +ARGYV + +F+ Sbjct: 3876 EQHFEEQIPIGKPIANSTAYIVDGNNQPQPIGVPGELCVGGDGVARGYVNKPELTAEKFV 3935 Query: 177 HNPHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353 NP P +YRTGD L G I Y GR D QVKIRG+R++L E++ +S V Sbjct: 3936 PNPF--APG-ETMYRTGDLARWLPDGTIEYLGRIDQQVKIRGYRIELGEIETVLSQQAQV 3992 Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVL 530 VV +E +N + PE + A + ++ L YM+P +++E +P+ Sbjct: 3993 KEAVVAV--IEEANGQKALCAYFVPEQAVDAAELREAMSKQLPGYMVPAYYVQMEKLPLT 4050 Query: 531 VNGKV 545 NGKV Sbjct: 4051 ANGKV 4055 Score = 105 bits (253), Expect = 5e-22 Identities = 67/179 (37%), Positives = 97/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIGVP N +YLLD +M+ V G GE+ +AG +A+GY + +FI NP Sbjct: 772 SVPIGVPADNVQLYLLDASMQPVPVGSLGEMYIAGDGVAKGYFNRPELTKEKFIDNPF-- 829 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P K+YRTGD L G + YAGR D QVKIRGHR+++ E++ ++ V VV+ Sbjct: 830 RPG-TKMYRTGDLAKWLPDGNMEYAGRMDYQVKIRGHRIEMGEIETRLTQHEAVKEAVVI 888 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ES + A++ E ++ + L +L YMIP I + +P+ NGKV Sbjct: 889 VEKDESGQNVLYAYLV--SERELTVAELREFLGRTLPSYMIPSFFIRLAEIPLTANGKV 945 Score = 100 bits (240), Expect = 2e-20 Identities = 60/178 (33%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 + IG P++N VY++DE G GE+C+ G LARGY+ + +F+ NP Sbjct: 5969 ITIGRPLANVQVYIVDEQHHLQPIGVVGELCIGGAGLARGYLNKPELTAEKFVANPFR-- 6026 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++Y+TGD G I Y GRAD QVK+RG+R+++ E++ AV +D VV+ Sbjct: 6027 PG-ERMYKTGDLVKWRTDGTIEYIGRADEQVKVRGYRIEIGEIESAVLAYQGIDQAVVVA 6085 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 +++ L + A +S + + L L YMIP +E++ +P+ NGKV Sbjct: 6086 RDDDATAGSYLCAYFVAATA-VSVSGLRSHLAKELPAYMIPSYFVELDQLPLSANGKV 6142 Score = 95.1 bits (226), Expect = 9e-19 Identities = 61/181 (33%), Positives = 95/181 (52%), Gaps = 4/181 (2%) Frame = +3 Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPH 188 + +PIG PI N +Y+++ + + G GE+C+AG LARGY + ++ + F+ NP Sbjct: 1807 YSAIPIGKPIDNVRLYVVNASNQLQPVGVAGELCIAGDGLARGYWQREELTKASFVDNPF 1866 Query: 189 NTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 P +YRTGD L G I Y GR D QVKIRGHR++L E++ + V V Sbjct: 1867 --EPG-GTMYRTGDMVRYLPDGHIEYLGRIDHQVKIRGHRIELGEIEATLLQHEAVKAVV 1923 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542 V+ + A+V E + + L+++L YM+P + +E +P+ NGK Sbjct: 1924 VMARQDGKGQNSLYAYVV--AEQDIQTAELRTYLSATLPAYMVPSAFVFLEQLPLSANGK 1981 Query: 543 V 545 V Sbjct: 1982 V 1982 Score = 93.5 bits (222), Expect = 3e-18 Identities = 54/178 (30%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 + IG PI+N +Y++++ + G GE+C+ G LARGY +F+ +P Sbjct: 2848 ITIGRPIANTSLYIVNQYHQLQPIGVVGEICIGGRGLARGYWNKPALTEEKFVSHPFAAG 2907 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++Y+TGD G L G I Y GR D QVK+RG+R+++ E++ A+ + VV+ Sbjct: 2908 E---RMYKTGDLGKWLPDGTIEYIGRIDEQVKVRGYRIEIGEIESALLAAEKLTAAVVVV 2964 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 Y + + A+ T + ++ + + L+ L YMIP ++++ +P+ NGKV Sbjct: 2965 YEDQLGQSALAAYFT--ADEQLDVTKLWSHLSKRLPSYMIPAHFVQLDQLPLTPNGKV 3020 Score = 92.3 bits (219), Expect = 7e-18 Identities = 57/179 (31%), Positives = 92/179 (51%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVPIG P+ N +Y++D ++ G GE+C+ G +ARGY+ + +F+ NP Sbjct: 4926 TVPIGKPLPNMTMYVVDAHLNLQPVGVVGELCIGGAGVARGYLNRPELTEEKFVPNPF-- 4983 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +LYRTGD G + + GR D QVKIRG R++L E++ + + + VV+ Sbjct: 4984 APG-ERLYRTGDLAKWRADGNVEFLGRNDHQVKIRGVRIELGEIETQLRKLDGITEAVVV 5042 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E+ A+V + ++ + A L L MIP + ++ +P+ NGKV Sbjct: 5043 AREDRGQEKELCAYVV--ADHKLDTAELRANLLKELPQAMIPAYFVTLDALPLTANGKV 5099 >UniRef50_Q93H68 Cluster: Non-ribosomal peptide synthetase; n=1; Streptomyces avermitilis|Rep: Non-ribosomal peptide synthetase - Streptomyces avermitilis Length = 1768 Score = 108 bits (259), Expect = 9e-23 Identities = 64/178 (35%), Positives = 102/178 (57%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI N + +LD +R G PGE+C+AG LARGY+ + RF+ P Sbjct: 589 VPIGRPIDNTRILVLDSGLRPQPVGVPGELCIAGVGLARGYLGRPELTAERFVAAP---A 645 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD L G I Y GR D QVK+RG+R++L E++ ++ P V + VVL Sbjct: 646 AGEERVYRTGDLARWLPDGSIDYLGRIDHQVKVRGYRIELGEIEESLRRHPQVKDAVVLA 705 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E + +V + +A ++ ++++ L +L DYM+P +++ ++T P+ NGK+ Sbjct: 706 RKAEDGQTHLCGYVQ-SADA-LTEEDLKRHLGVTLPDYMVPARLVALDTFPLSPNGKL 761 >UniRef50_Q87WM7 Cluster: Non-ribosomal peptide synthetase, terminal component; n=1; Pseudomonas syringae pv. tomato|Rep: Non-ribosomal peptide synthetase, terminal component - Pseudomonas syringae pv. tomato Length = 3432 Score = 108 bits (259), Expect = 9e-23 Identities = 63/178 (35%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P++N Y+LDE ++ V G G + +AG L+RGY++ D RFI +PH T Sbjct: 2902 VPIGRPVANTRTYILDETLQPVPIGVTGNLYLAGVQLSRGYLKRVDLTAERFIPDPHGT- 2960 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +++Y TGD G I Y GR D Q+K+RG R++L E++ + P V VV Sbjct: 2961 PG-SRMYMTGDTARYRAHGEIEYLGRNDQQIKLRGFRIELGEIEMQLCAHPQVSQAVVSV 3019 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 ++ NP + A++ N + + S + L +L DYM + ++ +P+ NGKV Sbjct: 3020 NTSDADNPTLTAYLVCNADTQPSVDELRECLARTLPDYMADVCFQFLDHLPLTSNGKV 3077 Score = 106 bits (254), Expect = 4e-22 Identities = 60/177 (33%), Positives = 99/177 (55%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG P+ N+ +Y+LD ++ V G G++ +AG +LAR Y D RF+ NPH+ P Sbjct: 1845 PIGKPLFNSQMYVLDASLEPVPVGVRGDLYIAGVHLARCYWERPDITAERFVPNPHSLSP 1904 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A++Y+TGD L G I Y GR+D QVKIRG R++L EV+ A+ V + + Sbjct: 1905 G-ARMYKTGDVARYLPDGNIEYLGRSDHQVKIRGFRIELAEVEQALMAQETVASAAAMVR 1963 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 +++ ++ + ++ +I+ L +L DYM+P + + T+P+ +GKV Sbjct: 1964 EDRPGLKKLVGYLVAKSDCTLNIVDIKEHLRRTLPDYMVPTTFVILPTLPLTPSGKV 2020 Score = 100 bits (240), Expect = 2e-20 Identities = 56/176 (31%), Positives = 96/176 (54%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 +G PI+N + +LDEN R G PGE+ + G +ARGY+ D +F+ +P+ + Sbjct: 787 LGRPIANTVLRVLDENARLCATGSPGELHIGGEGVARGYLDRADLTAQKFVPDPYASGSG 846 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++Y+TGD L G I + GR D QVK+RG R++L E++ + + P V V+ Sbjct: 847 -ARIYKTGDLVRWLPNGEIEFLGRIDHQVKVRGFRIELGEIETRLVSFPSVRQGAVIVRE 905 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + +I+A++ + + + + L +L YMIP + +E P+ NGK+ Sbjct: 906 DQPGDQQIVAYLLVGEQYAAEPEQLRHHLAQTLPGYMIPNHFVVLEQFPLTPNGKL 961 >UniRef50_Q5ZTI3 Cluster: Peptide synthetase, non-ribosomal; n=2; Legionella pneumophila|Rep: Peptide synthetase, non-ribosomal - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 1453 Score = 108 bits (259), Expect = 9e-23 Identities = 58/159 (36%), Positives = 95/159 (59%), Gaps = 3/159 (1%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI N VY+LD M+ V G GE+ ++G LARGY+ + +F+ NP + + N Sbjct: 915 IGKPIMNTKVYVLDAKMQPVPIGIMGELYISGDGLARGYLNNPEFTIQKFLPNPFSNNKN 974 Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LYRTGD + GV+ Y GR D+QVKIRG+R+++ E++ + IP + C+V Sbjct: 975 -DRLYRTGDLVKWNSNGVLEYHGRCDNQVKIRGYRIEINEIESYLEKIPSIHQCIVKPEK 1033 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP 497 + + + A++ + +++SA +I A L ++ +YMIP Sbjct: 1034 NQDDSMSLSAYLVLEKNSQISAVDIRAILKQNIPEYMIP 1072 >UniRef50_A6E8C1 Cluster: Amino acid adenylation; n=1; Pedobacter sp. BAL39|Rep: Amino acid adenylation - Pedobacter sp. BAL39 Length = 1329 Score = 108 bits (259), Expect = 9e-23 Identities = 61/180 (33%), Positives = 102/180 (56%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHN 191 +TVPIG P SN +Y++D++ G PGE+ + G LA+GY+ FI +P Sbjct: 791 MTVPIGKPFSNTVIYVVDKHFNHCPVGVPGELYIGGRGLAKGYLGNPALTDQSFIKDPFA 850 Query: 192 THPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 T P AK+Y+TGD L G I Y GR D Q+KIRG+R++L E+ + + + V C V Sbjct: 851 TTPE-AKIYKTGDLVRWLPDGNIQYMGRIDDQIKIRGNRIELGEIQNVLLSHADVLQCAV 909 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + + ++ A++ N + + + L SL +YMIP++ ++++ +P+ NGK+ Sbjct: 910 VVEENQGNEKQLAAYIVQN--GVLDKELMIQHLQKSLPEYMIPRMFLQLDQIPLTANGKI 967 >UniRef50_A3WXS1 Cluster: Probable non-ribosomal peptide synthetase; n=2; Bradyrhizobiaceae|Rep: Probable non-ribosomal peptide synthetase - Nitrobacter sp. Nb-311A Length = 3272 Score = 108 bits (259), Expect = 9e-23 Identities = 58/180 (32%), Positives = 108/180 (60%), Gaps = 6/180 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNTH 197 VPIG+P++N V++LD ++ V G GE+ + G +ARGY G +F+ +P Sbjct: 1453 VPIGLPLANLRVHVLDNSLNEVPIGVTGELYIGGAGVARGYRGAAGLTAEQFVPDPFGRA 1512 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + +LYRTGD D+ G +++ GR+D Q+K+RG+RV+ EV A+ +P +++ VV+ Sbjct: 1513 GD--RLYRTGDRVRCDRAGRLIFIGRSDDQIKLRGYRVEPDEVGRALKALPGINDAVVIA 1570 Query: 375 YGV--ESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++ E++A+ + A+ ++ +L++ + DYM+P +I +E +P+ NGK+ Sbjct: 1571 RSIDGQAGRQELVAYCVPGDGVTLEAEAVKRQLSAIVPDYMVPSHMIVLERLPLTSNGKI 1630 Score = 97.5 bits (232), Expect = 2e-19 Identities = 62/179 (34%), Positives = 94/179 (52%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 T PIG P+ Y+LD ++ V G GE+ + G LARGY+ RFI +P Sbjct: 2986 TAPIGRPVGARTAYILDADLNVVPAGVTGELFIGGAGLARGYLNRSAMTAERFIPDPFGA 3045 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 N +LYRTGD D GVI Y GRAD QVKIRG R++L E++ + V V+ Sbjct: 3046 --NGDRLYRTGDLARWRDDGVIDYVGRADQQVKIRGFRIELGEIEACLIEQRGVRAAAVV 3103 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ ++A+ + +P + + L + L DYM+P ++ +E +P+ NGK+ Sbjct: 3104 AQDSKTGR-HLVAYASGDP--TLDGAALRDALAAVLPDYMVPATIVVLEQLPLSRNGKI 3159 Score = 46.8 bits (106), Expect = 3e-04 Identities = 38/147 (25%), Positives = 65/147 (44%), Gaps = 1/147 (0%) Frame = +3 Query: 99 EPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAKLYRTGDFGILDKGVILYAGRAD 278 E GE+ V G ++ GY D R + + A+ RTGD G + G ++ AGR Sbjct: 408 EVGEIWVTGPSVTLGYWNNPDATRQVF----VERDGARWLRTGDLGFIRDGALVVAGRLK 463 Query: 279 SQVKIRGHRVDLQEVDHAV-STIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNI 455 + +RG + +V+ AV + + V V + VE+ E + A + ++ Sbjct: 464 DVLIVRGQNIYPTDVEQAVEADVESVRRGRVAAFAVEADGQEGIGVAAEFSRAVLKGEDP 523 Query: 456 EAELTSSLTDYMIPQVIEIETVPVLVN 536 E L ++ ++ Q E V VL+N Sbjct: 524 EV-LAEAIGQAVLRQAQEYPAVIVLLN 549 >UniRef50_A0ZF81 Cluster: Amino acid adenylation protein; n=3; Bacteria|Rep: Amino acid adenylation protein - Nodularia spumigena CCY 9414 Length = 2558 Score = 108 bits (259), Expect = 9e-23 Identities = 61/174 (35%), Positives = 98/174 (56%), Gaps = 2/174 (1%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFA 209 IG PI+NN +Y+LD + + + G PGE+C+AG LARGY+ + + Sbjct: 806 IGQPIANNSIYILDPHNQPLPPGIPGELCIAGVGLARGYLNRPETTSEKFMEIDLFGKVE 865 Query: 210 KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVE 386 ++Y+TGD G + Y GR D QVK+RG R++L E++ + V VV+ Y + Sbjct: 866 RIYKTGDLARWCADGNLEYLGRIDEQVKLRGFRIELGEIESLLLQHSLVKEAVVILYETD 925 Query: 387 SSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 SNP ++A+VT ++ I+ L + L +YMIP Q++ +E +P+ NGK+ Sbjct: 926 -SNPRLVAYVTQAEKSVTLGIEIKEYLKNRLPNYMIPSQIMVLEQLPLTANGKL 978 Score = 81.8 bits (193), Expect = 9e-15 Identities = 44/118 (37%), Positives = 68/118 (57%), Gaps = 3/118 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG P+SN +Y+LD + + + G PGE+C+AG LARGY+ + +FI Sbjct: 1859 PIGKPLSNLRIYILDTDYQPLPPGIPGELCIAGVGLARGYLNRPELTAEKFIE--IELFG 1916 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 ++Y+TGD L G + Y GR D QVK+RG R++L E++ ++ P + VV+ Sbjct: 1917 KVERIYKTGDLARWLPDGNLEYLGRIDHQVKLRGFRIELSEIEASLLKHPKIQEAVVI 1974 >UniRef50_P27206 Cluster: Surfactin synthetase subunit 1; n=15; Bacillus|Rep: Surfactin synthetase subunit 1 - Bacillus subtilis Length = 3588 Score = 108 bits (259), Expect = 9e-23 Identities = 62/178 (34%), Positives = 93/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG + NN +Y+LD+ R EG GE+ +AG + RGY+ + +F+ +P Sbjct: 777 VPIGKALGNNRLYILDQKGRLQPEGVAGELYIAGDGVGRGYLHLPELTEEKFLQDPFVPG 836 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD L G I Y GR D QVK+RG+R++L E++ + P V VVL Sbjct: 837 D---RMYRTGDVVRWLPDGTIEYLGREDDQVKVRGYRIELGEIEAVIQQAPDVAKAVVLA 893 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545 E N E+ A+V P + + + L DYM+P E+ +P+ +GKV Sbjct: 894 RPDEQGNLEVCAYVVQKPGSEFAPAGLREHAARQLPDYMVPAYFTEVTEIPLTPSGKV 951 Score = 106 bits (255), Expect = 3e-22 Identities = 67/178 (37%), Positives = 100/178 (56%), Gaps = 3/178 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194 ++ IG I+N VY+L E + EG GE+CVAG LARGY+ +D RF+ +P Sbjct: 2849 SLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAKRFVADPFV- 2907 Query: 195 HPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD G I Y GR D QVK+RG+R++L E++ ++ + V + V Sbjct: 2908 -PG-ERMYRTGDLVKWTGGGIEYIGRIDQQVKVRGYRIELSEIEVQLAQLSEVQDAAVTA 2965 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + N I A+VT PE+ + +++ L +L DYMIP + + +PV NGKV Sbjct: 2966 VKDKGGNTAIAAYVT--PES-ADIEALKSALKETLPDYMIPAFWVTLNELPVTANGKV 3020 Score = 99 bits (238), Expect = 3e-20 Identities = 60/180 (33%), Positives = 94/180 (52%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 L+VPIG P+SN VY+LD G GE+CV G L +GY + +F+ +P Sbjct: 1814 LSVPIGKPVSNTEVYILDRTGHVQPAGIAGELCVTGEGLVKGYYNRPELTEEKFVPHPFT 1873 Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 + ++Y+TGD L G I + GR D QVKIRG ++L E++H + T V VV Sbjct: 1874 SG---ERMYKTGDLARWLPNGTIEFIGRIDHQVKIRGQAIELGEIEHQLQTHDRVQESVV 1930 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 L + + + A+ E +S++ + L YM+P V I+++ +P+ NGK+ Sbjct: 1931 LAVDQGAGDKLLCAYYV--GEGDISSQEMREHAAKDLPAYMVPAVFIQMDELPLTGNGKI 1988 >UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomonas syringae pv. syringae|Rep: Amino acid adenylation - Pseudomonas syringae pv. syringae (strain B728a) Length = 9498 Score = 107 bits (258), Expect = 1e-22 Identities = 57/176 (32%), Positives = 103/176 (58%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTHPN 203 IG P++N +YLLD + + V G GE+ + G +ARGY+ ++ + RF+ +P + P+ Sbjct: 3013 IGKPMANTRIYLLDAHQQPVPYGVAGEIYIGGDGVARGYLNLEEVNAERFLADPFSESPD 3072 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++Y+TGD + G I Y GR D QVK+RG R++L E++ + V VV+ Sbjct: 3073 -ARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCTGVKEAVVIARE 3131 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V P+++++A ++ AEL L +YM+P + ++ +P+ N K+ Sbjct: 3132 DNPGDKRLVAYVVAQPQSQLTAADLRAELAPQLAEYMLPSAFVLLDELPLTPNRKL 3187 Score = 106 bits (254), Expect = 4e-22 Identities = 57/176 (32%), Positives = 100/176 (56%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH--RFIHNPHNTHPN 203 IG P++N +YLLD + + V G GE+ + G +ARGY+ ++ + RF+ +P + P+ Sbjct: 4100 IGKPMANTRIYLLDAHQQPVPYGVAGEIYIGGDGVARGYLNLEEVNAERFLADPFSESPD 4159 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++Y+TGD + G I Y GR D QVK+RG R++L E++ + V VV+ Sbjct: 4160 -ARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCKGVKEAVVIARE 4218 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+V P+ +++A + AEL L +YM+P + ++ +P+ N K+ Sbjct: 4219 DNPGEKRLVAYVVAQPQTQITAAELRAELAPQLAEYMLPSAFVLLDELPLTPNRKL 4274 Score = 103 bits (247), Expect = 3e-21 Identities = 60/181 (33%), Positives = 100/181 (55%), Gaps = 5/181 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 L++PIG P +N VY+LD V G GE+ + G +A GY+ + RF +P + Sbjct: 6218 LSLPIGKPNANVRVYVLDARREPVPMGVVGEIYIGGTGVALGYLNRPELTAERFSEDPFS 6277 Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 A+LYRTGD L G + Y R D QVK+RG RV+L E++ + V N VV Sbjct: 6278 QQAG-ARLYRTGDLARWLPDGNLEYLARNDGQVKVRGFRVELGEIESVLHLCDGVRNSVV 6336 Query: 369 LCYGVESSNPEILAFVTINPEA-RMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542 + + + ++A+ T++ +++ A+L++ L +YM+P V + ++ +P+ +NGK Sbjct: 6337 VAHEASPGDTRLVAYYTVHAGVDAPDPEDLRAQLSADLAEYMVPSVFVRLDALPLTLNGK 6396 Query: 543 V 545 V Sbjct: 6397 V 6397 Score = 103 bits (246), Expect = 4e-21 Identities = 62/180 (34%), Positives = 102/180 (56%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PI+N +++LD + G GE+ + G +ARGY+ D RFI +P ++ Sbjct: 832 SVPIGRPIANIQMHVLDTLGQLQPLGVAGELHIGGIGVARGYLNQPDLSAERFIADPFSS 891 Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LY+TGD G L G + Y GR D QVKIRG R+++ E++ A++ P V VV Sbjct: 892 DPQ-ARLYKTGDVGRWLANGALEYLGRNDFQVKIRGLRIEIGEIEAALAKHPAVHEAVVT 950 Query: 372 CYGVESSNPEILAFVTINPE-ARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ T + E + + + + L L +YM+P + + +E +P+ NGK+ Sbjct: 951 AREDIPGDKRLVAYYTQSAEHTAVDLEILRSHLQQQLPEYMVPAIYVLLEAMPLTSNGKL 1010 Score = 99 bits (238), Expect = 3e-20 Identities = 56/176 (31%), Positives = 97/176 (55%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+N V++LD G GE+ + G +ARGY+ + RFI +P + N Sbjct: 8383 IGRPIANVQVHVLDARGEPAPLGVAGEIHIGGSGVARGYLNRDELSAERFIVDPFSDVAN 8442 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LY+TGD G L G + Y GR D QVK+RG R++L E+++ + +P + +V+ Sbjct: 8443 -ARLYKTGDLGRWLADGTLEYMGRNDFQVKVRGFRIELGEIENVLLAVPGIREAIVIARN 8501 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + V ++A+++ +EL L +YM+P ++++ +P+ NGK+ Sbjct: 8502 DSQGDSDSQRLVAYVCGESVAAEHLRSELLRHLPEYMVPSAFVQLDALPLTANGKL 8557 Score = 98.7 bits (235), Expect = 8e-20 Identities = 61/180 (33%), Positives = 100/180 (55%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PI+N +++LD + G GE+ + G +ARGY+ D RFI +P + Sbjct: 1922 SVPIGRPIANIQMHVLDALGQLQPLGVAGELHIGGIGVARGYLNQPDLSAERFIADPFSE 1981 Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A+LY+TGD G L G + Y GR D QVKIRG R+++ E++ A++ P V VV Sbjct: 1982 DRQ-ARLYKTGDVGRWLANGALEYLGRNDFQVKIRGLRIEIGEIEAALAKHPAVHEAVVT 2040 Query: 372 CYGVESSNPEILAFVTINPE-ARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ T + E + + + + L L +YM+P + + +E +P+ NGK+ Sbjct: 2041 AREDIPGDKRLVAYYTQSAEHTAVDLEILRSHLQQQLPEYMVPAIYVLLEAMPLTSNGKL 2100 Score = 88.6 bits (210), Expect = 8e-17 Identities = 53/176 (30%), Positives = 93/176 (52%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG + + + +LD+ + V G GE+ + G +AR Y+ + RFI +P+ Sbjct: 7295 IGPALDDLCLRILDDYQQPVPVGVNGEIYIGGAGVARHYLNRTELNAERFIADPYALQSG 7354 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LYRTGD G ++Y GR DSQ+KIRG R++L E++ + P V +V+ Sbjct: 7355 -ARLYRTGDVAHYRSDGGVVYVGRNDSQIKIRGFRIELGEIEAQLLACPDVREAMVIVRE 7413 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A++ A + + ++L S L ++M+P + +ET P+ NGK+ Sbjct: 7414 DRPGDKRLVAYLIAEDGAAPESALLRSQLASVLAEHMLPSAFVTLETWPLTTNGKL 7469 Score = 82.6 bits (195), Expect = 5e-15 Identities = 55/183 (30%), Positives = 96/183 (52%), Gaps = 9/183 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG ++N +YLLDE + V G GE+ + G +ARGY+ + RF+ NP Sbjct: 5162 LPIGRALANTRIYLLDELGQAVPPGVAGELYIGGAGIARGYLNLQQLTAERFMDNPFVAG 5221 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYR+GD G I + GR DSQ K+RG R++L E++ ++ + V +V+ Sbjct: 5222 ---ERLYRSGDMARYRADGNIEFLGRNDSQAKLRGLRLELGEIEARLAEVAGVRESLVVI 5278 Query: 375 YGVESSNPEILAF---VTINPEA--RMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536 P+++A+ E+ ++ + + +L +L +YMIP + + +P+ N Sbjct: 5279 REDSGGTPKLIAYFVEYATRDESGPALTPRALRQQLQLNLPEYMIPAAFVRMAALPLSAN 5338 Query: 537 GKV 545 GK+ Sbjct: 5339 GKL 5341 >UniRef50_Q1D3K4 Cluster: Non-ribosomal peptide synthase; n=2; Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide synthase - Myxococcus xanthus (strain DK 1622) Length = 3292 Score = 107 bits (258), Expect = 1e-22 Identities = 66/179 (36%), Positives = 98/179 (54%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197 VPIG P+ Y+LD + V G GE+ + G LARGY R RF+ +PH T Sbjct: 1471 VPIGQPLRTMGAYVLDGRLEPVPAGGVGELWLTGEGLARGYFRDPALTAERFMADPHATT 1530 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +++YRTGD + GV+ Y GRAD QVK+RG RV+L E++ A+ V + +VL Sbjct: 1531 PG-SRIYRTGDLARMRADGVLEYLGRADDQVKVRGFRVELGEIETALRACEGVRDAIVLL 1589 Query: 375 YGVES-SNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +G + ++A+ PE SA + A+L + L YM+P ++ + P +GKV Sbjct: 1590 HGENAGKEARLIAYAVAAPEVAPSA--LRAQLAARLPPYMVPAAIVRLAAFPYGSSGKV 1646 Score = 103 bits (248), Expect = 2e-21 Identities = 61/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P++ V+LLD + V G PGE+ AG LARGY+ D RF+ +P + Sbjct: 2526 VPIGAPVTGTRVHLLDAGLEPVPLGAPGELYCAGDGLARGYMGHADLTAERFLPDPFSRK 2585 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +++YRTGD G I + GR D+QVK+RG R++ EV+ + P V + V+ Sbjct: 2586 PG-SRMYRTGDLACWRADGSIEFLGRVDNQVKVRGFRIEPGEVEATLLRHPAVRDAAVVA 2644 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 G + ++A V + + +++ ++ L L ++MIP V+ +P+ NGKV Sbjct: 2645 AGERADTKRLVAHVVLRDASAITSGDLRDYLEPQLPEHMIPSAVVFHHALPLSPNGKV 2702 Score = 42.7 bits (96), Expect = 0.005 Identities = 33/116 (28%), Positives = 46/116 (39%), Gaps = 1/116 (0%) Frame = +3 Query: 72 ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAKLYRTGDFGILDKG 251 E R+GE GE+ V+G ++A GY + RTGD G L G Sbjct: 391 ETFELRRDGEIGEIWVSGSSVAGGYWGQPEATTRTFQARLRGTGEGPFLRTGDLGFLRDG 450 Query: 252 VILYAGRADSQVKIRGHRVDLQEVDHAVSTI-PCVDNCVVLCYGVESSNPEILAFV 416 + GRA + IRG Q+++ V P V + VE+ E L V Sbjct: 451 ELFVTGRAKDLIIIRGLNHFPQDIEFTVEKCHPAVRPGSGAAFSVEADGTEQLVVV 506 >UniRef50_Q0RMQ5 Cluster: Putative non-ribosomal peptide synthetase; n=1; Frankia alni ACN14a|Rep: Putative non-ribosomal peptide synthetase - Frankia alni (strain ACN14a) Length = 2623 Score = 107 bits (258), Expect = 1e-22 Identities = 67/181 (37%), Positives = 100/181 (55%), Gaps = 7/181 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIGVPI N VY+LD +R V G PGE+ +AG LARGY+ G RF+ P Sbjct: 2338 VPIGVPIWNMRVYVLDAGLRPVPPGVPGELYLAGVGLARGYLGQVGLTAGRFVACPFGGV 2397 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD + G + Y GR+D QVK+RG R++L E++ A+++ P + V + Sbjct: 2398 GE--RMYRTGDVVRWNSAGQVEYLGRSDFQVKVRGFRIELGEIEQALTSQPGIGGAVAIV 2455 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEA---ELTSSLTDYMIPQVI-EIETVPVLVNGK 542 ++ N ++A+V +A + +IE L L +YM+P VI + P +GK Sbjct: 2456 REDQAGNQRLVAYVVAEDQASVGQPDIEEVTDRLRRQLPEYMVPSVIVPLTEFPTTPSGK 2515 Query: 543 V 545 V Sbjct: 2516 V 2516 Score = 72.1 bits (169), Expect = 8e-12 Identities = 59/194 (30%), Positives = 87/194 (44%), Gaps = 21/194 (10%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNTHP 200 PIG P+ N Y+L + V G GE+ VAG L RGY G RF+ NP HP Sbjct: 806 PIGTPLGNMRAYVLGPGLAPVPPGVVGELYVAGRCLGRGYHGQPGLTAVRFVANPW-CHP 864 Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD D G + GR D QVK+RG R++ EV+ + VV+ Sbjct: 865 G-ERMYRTGDLARRDADGRLECVGRGDGQVKVRGFRIETAEVEAVCELHLGISRAVVVGR 923 Query: 378 GVESSNPEILAFVT-----------------INPEARMSAKNIEAELTSSLTDYMIPQV- 503 S ++A+V ++ ++ SA + L + L DYM+P Sbjct: 924 EAPSGGRRLVAYVVHTGEGAVGDDGAGGIGDVDMQSGASAAELRRFLAARLPDYMVPSAF 983 Query: 504 IEIETVPVLVNGKV 545 + + +P GK+ Sbjct: 984 VVVGELPYGPTGKL 997 >UniRef50_A5IDB4 Cluster: Peptide synthetase; n=4; Legionella pneumophila|Rep: Peptide synthetase - Legionella pneumophila (strain Corby) Length = 507 Score = 107 bits (258), Expect = 1e-22 Identities = 64/182 (35%), Positives = 104/182 (57%), Gaps = 5/182 (2%) Frame = +3 Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPH 188 F TVPIG PI N ++LDE + EPGE+ ++G LA+GY+ FI NP+ Sbjct: 321 FDTVPIGKPIQNTQFFVLDEQLNSTGF-EPGELYISGVGLAQGYLNNPVLTQASFIDNPY 379 Query: 189 NTHPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 P K+YRTGD ++ G +L+ GR D QVK+RG R++L E+ H + P + + V Sbjct: 380 L--PG-EKMYRTGDIVRWNQEGELLFLGRKDDQVKLRGIRIELGEIQHHLLAHPNIHDAV 436 Query: 366 VLCYGVESSNPEILAF-VTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNG 539 V+C V+ + ++ F + N + ++ + +++ L + L DYMIP+ + + P+ NG Sbjct: 437 VVCEKVDCLDHRMVVFLIANNKQTKIGSAELKSFLKNRLPDYMIPEHYLWLSAFPIKENG 496 Query: 540 KV 545 K+ Sbjct: 497 KI 498 >UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5; root|Rep: Amino acid adenylation domain - Clostridium cellulolyticum H10 Length = 3235 Score = 107 bits (258), Expect = 1e-22 Identities = 62/178 (34%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V IG PI+N VY+LD M+ G PGE+ + G LARGY++ + +FI NP ++ Sbjct: 1436 VSIGKPIANTTVYVLDNEMKPTPVGIPGELYIGGTGLARGYLKLPELTQEKFIPNPFSSE 1495 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++LY+TGD + G I + GR D QVKIRG R++L E++ ++ P + VV+C Sbjct: 1496 EG-SRLYKTGDIVRFMPDGNIEFIGRGDHQVKIRGFRIELGEIETLLNKNPLISQSVVVC 1554 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+V I +A L + L DYMIP + +++ P+ N K+ Sbjct: 1555 REISLGEKALIAYV-IPKSQETAATTFREYLRNRLPDYMIPSYFVILDSFPMTPNNKI 1611 Score = 54.0 bits (124), Expect = 2e-06 Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 5/176 (2%) Frame = +3 Query: 33 GVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAK 212 G PI + YV + D + + E + G +C++G N+ GY K+ R Sbjct: 374 GYPIYDCYVRICDIDNNDIGENKIGYICISGANVTSGYYNNKEATRKAITKDG------- 426 Query: 213 LYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGV--- 383 TGD G + G ++ GRA + ++G +++ + +D ++ G Sbjct: 427 WLNTGDLGFMRDGRLVITGRAKDVIFVKGQNYYSHDIERVAQEVDGIDVGKIVAVGAFNE 486 Query: 384 ESSNPEILAFVTINPEARMSAKNIEA--ELTSSLTDYMIPQVIEIETVPVLVNGKV 545 + + E++ FV + + + +L S + QVI I+++P +GKV Sbjct: 487 KIKSDELILFVLFKMKVDKFIGLVRSLKKLISERMGIEVSQVIPIKSIPKTTSGKV 542 >UniRef50_Q5JCL8 Cluster: Putative non-ribosomal peptide synthetase; n=1; Pseudomonas fluorescens|Rep: Putative non-ribosomal peptide synthetase - Pseudomonas fluorescens Length = 1432 Score = 107 bits (257), Expect = 2e-22 Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 +PIG PI N Y++D N+ V G PGE+ +AG NLARGY+ + RF+ NP Sbjct: 752 IPIGYPIDNTDAYIVDLNLNPVPPGVPGEIMLAGQNLARGYLGKPAQTAQRFLPNPFGN- 810 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++Y TGD G G I Y GR D QVKIRGHR++L EV H + + +V Sbjct: 811 ---GRVYATGDLGRRWSSGAISYLGRRDQQVKIRGHRIELNEVAHLLCQALELKEAIVFA 867 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A I + + ++ I+ EL L Y+IP Q++ ++ +P GKV Sbjct: 868 QHAGTEQARLVA--AIEQQPGLHSEGIKQELLRHLPAYLIPSQLLLLDELPRTATGKV 923 >UniRef50_Q1D3K7 Cluster: Non-ribosomal peptide synthase; n=1; Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide synthase - Myxococcus xanthus (strain DK 1622) Length = 1515 Score = 107 bits (257), Expect = 2e-22 Identities = 64/179 (35%), Positives = 101/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+P+ PI N VY+LD +R V G GE+ V G LARGY+ D F+ NP +T Sbjct: 773 TLPLERPIDNTQVYVLDARLRPVAVGMTGELYVGGAALARGYLNRPDLTAQSFLPNPFST 832 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A++YRTGD L G + + GRAD+QVK G+R++L E+ HA++ P V + V++ Sbjct: 833 TPG-ARMYRTGDLARHLPDGTLEHLGRADNQVKYHGYRIELNELRHALNQHPQVRDSVMM 891 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + N ++A+ E + + A L L + ++P V + ++ +P+ +NGKV Sbjct: 892 LKRDTNGNEVLVAYYVSRQEQEHA--QLRAFLAERLIEEVLPNVYVHLKKLPLTLNGKV 948 >UniRef50_Q08XI8 Cluster: Beta-lactamase, putative; n=3; Bacteria|Rep: Beta-lactamase, putative - Stigmatella aurantiaca DW4/3-1 Length = 3136 Score = 107 bits (257), Expect = 2e-22 Identities = 60/176 (34%), Positives = 93/176 (52%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PIS Y+LD + V G PGE+ ++G LARGY+ + RF+ NP +T P Sbjct: 1511 IGRPISGTRAYVLDRQLHLVPRGVPGELYLSGSGLARGYINRPELTAERFLPNPFSTEPG 1570 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++LY+TGD G + Y GR D QVKIRG R++L E++ + T P + VL + Sbjct: 1571 -SRLYKTGDLARFAVDGNLEYLGRIDHQVKIRGFRIELGEIESILLTQPGLHQAAVLAHE 1629 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V + + L L DYM+P + ++ +P+ NGK+ Sbjct: 1630 EAPGDKRLVAYVVAARNHSFTPAELRRLLKERLPDYMVPSAFVLLDALPLTPNGKL 1685 Score = 33.5 bits (73), Expect = 3.3 Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 2/103 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLD--ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTH 197 V G + N + ++D ++ C G+ GE+ V G ++A+GY + I Sbjct: 412 VGCGQTVPNQEILIVDPVSSVPCP-PGKVGEIWVCGPSVAQGYWQKPTETGQIFQARPAS 470 Query: 198 PNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVD 326 RTGD G L + + GR + IRG Q+++ Sbjct: 471 GGERVYLRTGDLGFLKERELFVTGRQKDLIIIRGRNHFPQDLE 513 >UniRef50_A4PHM3 Cluster: Hybrid non ribosomal peptide synthetase-polyketide synthase; n=2; cellular organisms|Rep: Hybrid non ribosomal peptide synthetase-polyketide synthase - Streptomyces virginiae Length = 2589 Score = 107 bits (257), Expect = 2e-22 Identities = 64/182 (35%), Positives = 101/182 (55%), Gaps = 7/182 (3%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHN 191 TVPIG PI+ ++++DE M V +G PGE+ + G +A GY G+ RF+ +P Sbjct: 1225 TVPIGRPIARTRIHVVDERMARVPDGTPGEIVIGGAGVALGY-HGRPELTAERFVASPFA 1283 Query: 192 THPNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 P+ +LYRTGD G L G I Y GR D Q K+RG R++ +EV+ A++ +P V V Sbjct: 1284 DDPS-PRLYRTGDLGQLGPDGEIRYLGRIDGQFKLRGLRIEPEEVEAALTELPGVSEARV 1342 Query: 369 LCYGVESSNPEILAFVTINPEARM--SAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNG 539 L ++ +ILA V + + + S + +L SL Y++P ++ +P+ NG Sbjct: 1343 LPVTDPATGEQILAAVCVEADGTLAPSVGQMRRDLARSLPSYLVPSSFRFVDRLPLTANG 1402 Query: 540 KV 545 K+ Sbjct: 1403 KL 1404 >UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1; Clostridium cellulolyticum H10|Rep: Amino acid adenylation domain - Clostridium cellulolyticum H10 Length = 4196 Score = 107 bits (257), Expect = 2e-22 Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG PI N +Y+LD+N + V +G GE+C+ G L RGY G RFI + Sbjct: 1622 VPIGKPIDNVQIYILDKNQKLVPQGMVGELCIGGIGLTRGYYNDPGLTKERFIECEGISG 1681 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 K+YRTGD +G I + GR D+QVKIRG+R+++ E++ ++ + P + V + Sbjct: 1682 ---RKVYRTGDLAKWTQEGNIEFLGRVDNQVKIRGYRIEMGEIEASILSHPAIREAVAIA 1738 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + I A++ + +S + L SL YMIP + ++IE +P+ NGK+ Sbjct: 1739 KEDSTGGKYICAYIV--SDTGLSITELRDYLQKSLPGYMIPSRFVQIEKMPLTPNGKI 1794 Score = 105 bits (251), Expect = 9e-22 Identities = 62/178 (34%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG P+ N VY+L EN + G GEV ++G + GY+ + RFI NP N Sbjct: 579 IPIGKPMPNVQVYILGENQELIPRGCIGEVYISGTGVGVGYLSREQMTSERFIPNPFNVD 638 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 K+Y+TGD G L G I + GR D QVKIRG+R++L E++ + + VV Sbjct: 639 K---KMYKTGDLGRWLPDGNIEFIGRKDGQVKIRGYRIELGEIEAQLQKHENIREAVVTD 695 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +S N + A+ T N ++ + L+ + +YMIP ++IE +P+ +NGK+ Sbjct: 696 RKEDSENKVLCAYFTAN--EKLGVTQLREHLSDKIPEYMIPTYFVQIEKMPLTINGKL 751 Score = 99 bits (238), Expect = 3e-20 Identities = 58/177 (32%), Positives = 99/177 (55%), Gaps = 3/177 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 V IG PI+N + +++ +N++ + G GEVC+ G +LARGY+ + + P Sbjct: 3727 VSIGGPIANTQILIMNGDNLQPI--GVAGEVCIGGDSLARGYLNRSELTKEKFVSSELVP 3784 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +LY+TGD + G I + GR D+QVKIRG+R++L E++ + ++ CVV+ Sbjct: 3785 G-KRLYKTGDLAKWMPDGSIAFMGRIDNQVKIRGYRIELDEIEKCILKYNLINECVVIAQ 3843 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E SN +++ + + E +S I + L DYMIP + + + ++P+ NGKV Sbjct: 3844 EDEFSNKQLICYYVSSEEITVS--EIMQHIGRDLPDYMIPGIYVRLASIPLTPNGKV 3898 Score = 86.2 bits (204), Expect = 4e-16 Identities = 55/179 (30%), Positives = 88/179 (49%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNT 194 TVPIG + + LL+++ + E GE+ L++GY + K H+F NP Sbjct: 2681 TVPIGYELEGVSIQLLNDDNKAAGIYECGELVYHSHYLSQGYWNLDEKTNHQFERNPETG 2740 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 Y++GD +L G I + GR D+QVKIRG R++L E++ V + + C + Sbjct: 2741 E---VIAYKSGDLARLLPSGTIEHLGRKDTQVKIRGMRIELTEIESVVGGLKGIRECAAI 2797 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545 + I+ F E + K + L S L +YMIP ++ +E++P NGKV Sbjct: 2798 VLEKPNQENTIVVFYVPENEEVIENKQFKLMLKSKLPEYMIPSLLYPVESIPHTPNGKV 2856 >UniRef50_Q881Q3 Cluster: Non-ribosomal peptide synthetase, terminal component; n=5; cellular organisms|Rep: Non-ribosomal peptide synthetase, terminal component - Pseudomonas syringae pv. tomato Length = 5929 Score = 107 bits (256), Expect = 2e-22 Identities = 64/180 (35%), Positives = 98/180 (54%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PI N VY+L+ R G GE+ + G +A GY+ + +FI +P + Sbjct: 2977 SVPIGRPIGNTRVYVLNAQQRLAPLGVIGELYIGGDGVALGYLNRPELTVEKFIADPFSD 3036 Query: 195 HPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A +YRTGD G L+ G + GR D QVKIRG R++L E+ + + +P + VVL Sbjct: 3037 QPG-AMMYRTGDLGRWLEDGQLECLGRNDDQVKIRGFRIELGEIVNCLHQLPGIREAVVL 3095 Query: 372 CYGVESSNPEILAFVTINPEARMSAK-NIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E N ++A+ T + A + A + ++L DYM+P IE+ +P+ NGK+ Sbjct: 3096 AREDEPGNVRLVAYFTSQQDVEAPAPGQMRAHMQANLPDYMVPVAFIELTALPLTANGKL 3155 Score = 105 bits (253), Expect = 5e-22 Identities = 61/180 (33%), Positives = 100/180 (55%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++ IG PI+N VYLLD + V G GE+ + G ++ARGY+ RF+ +P Sbjct: 852 SLDIGKPIANTSVYLLDSLHKLVPFGVAGELYIGGESVARGYLNQPQLTAERFLRDPFAE 911 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A++YRTGD + G + Y GR D QVK+RG R++L E++ S +P ++ +VL Sbjct: 912 PPQ-ARMYRTGDLARWNPDGTLEYLGRNDDQVKLRGVRIELGEIESQFSQLPGIEEALVL 970 Query: 372 CYGVESSNPEILAFVTINPEARMS-AKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E P ++ + T +A S +++ L + L YM+P ++ +++ P+ NGKV Sbjct: 971 AREDEPGQPRLVGYFTERADATPSRLEDLRTALAARLPAYMVPGALVRLDSWPLTANGKV 1030 Score = 105 bits (253), Expect = 5e-22 Identities = 60/180 (33%), Positives = 101/180 (56%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++ IG PI+N VYLLDE + V G GE+ + G +ARGY+ RF+ +P Sbjct: 4021 SLDIGKPIANTRVYLLDEQQQLVPLGVAGELYIGGEGVARGYLNQPQLTAERFLLDPFAG 4080 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P+ A++YRTGD + G + Y GR D QVKIRG R++L E++ ++ +P ++ +V+ Sbjct: 4081 QPH-ARMYRTGDLARWNADGTLDYLGRNDDQVKIRGVRIELGEIEAQLAQLPGIEEALVM 4139 Query: 372 CYGVESSNPEILA-FVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E ++A F+ A ++A + +++ + L YM+P + ++ P+ NGKV Sbjct: 4140 AREDEPDQSRLVAYFIERADSATVAAAQLRSDMLARLPGYMVPSAFVRLDAWPLTANGKV 4199 Score = 103 bits (248), Expect = 2e-21 Identities = 60/176 (34%), Positives = 100/176 (56%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+++ +Y+LD + + V G PGE+ + G +ARGY+ D RF+ +P + + Sbjct: 5083 IGKPVAHARLYVLDAHSQPVPLGVPGELYIGGTGVARGYLNRPDLTAERFLDDPFS-NVT 5141 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD L G + Y GR D QVKIRG RV+L E++ ++ P V VV Sbjct: 5142 AARMYRTGDLVRWLADGTLEYLGRNDDQVKIRGVRVELGEIEQQLAQCPGVAEAVVTTQR 5201 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 +E ++A+ T +A + + + ++L L +YM+P + ++ +P+ NGKV Sbjct: 5202 LEDGTLRLVAYFT-RRDAALDSATLRSQLLGRLPEYMVPATYVGLDALPLTQNGKV 5256 Score = 89.8 bits (213), Expect = 4e-17 Identities = 58/178 (32%), Positives = 94/178 (52%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200 PIG I++ +Y+LD V G GE+ V G +ARGY+ + RF+ NP + H Sbjct: 1914 PIGKRIADLQLYVLDTCGEPVPLGVVGELYVGGAGVARGYLNREALTAERFLDNPFS-HA 1972 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A++YRTGD + G + Y GR D QVKIRG R++L E+ ++ P V + VV+ Sbjct: 1973 ADARIYRTGDLARWMADGSLEYLGRNDEQVKIRGFRIELGEIASRLNDHPQVLDAVVVAR 2032 Query: 378 GVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++ + T + + + + A L+ L DYM+P + + +P+ NGK+ Sbjct: 2033 EDVPGDKRLVGYYTCAEDQTGLDIEQLRAWLSGLLPDYMVPAAFVRLAGLPITANGKL 2090 >UniRef50_Q2Y7Z5 Cluster: Amino acid adenylation; n=2; Nitrosospira multiformis ATCC 25196|Rep: Amino acid adenylation - Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) Length = 4037 Score = 107 bits (256), Expect = 2e-22 Identities = 68/184 (36%), Positives = 102/184 (55%), Gaps = 9/184 (4%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 +VPIG PIS Y+LD ++ V +G GE+ + G LARGY+ G RFI +P + Sbjct: 2365 SVPIGKPISGLQAYILDVHLNQVPQGVAGELYLGGIGLARGYLNRGGLTADRFIADPFD- 2423 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LYRTGD G I Y GR D QVKIRG R++L E++ + P V VV+ Sbjct: 2424 -ETGGRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIETQLLAQPEVREAVVV 2482 Query: 372 C-YGVESSNP----EILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLV 533 G +SNP ++A+V+ + + A + L +L DYM+P ++ +E++P+ Sbjct: 2483 AREGSNASNPTGGARLIAYVSAHATTDLDAARLREALARTLPDYMLPSMIVVLESLPLNP 2542 Query: 534 NGKV 545 +GKV Sbjct: 2543 SGKV 2546 Score = 105 bits (251), Expect = 9e-22 Identities = 65/183 (35%), Positives = 100/183 (54%), Gaps = 9/183 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +PIG P+ + Y+LD ++ V G GE+ + G LARGY+ G RFI +P + Sbjct: 831 MPIGCPVGDRIAYILDSDLNPVPAGVAGELYLGGIGLARGYLNRGGLTADRFIADPFD-- 888 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD G I Y GR D QVKIRG R++L E++ + P V VV+ Sbjct: 889 ETGGRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIETQLLAQPEVREAVVVA 948 Query: 375 -YGVESSNP----EILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVN 536 G +SNP ++A+V+ + + A + L +L DYM+P ++ +E++P+ + Sbjct: 949 REGSSASNPTGGARLIAYVSAHATTDLDAARLREALARTLPDYMLPSMIVVLESLPLNPS 1008 Query: 537 GKV 545 GKV Sbjct: 1009 GKV 1011 Score = 96.3 bits (229), Expect = 4e-19 Identities = 66/188 (35%), Positives = 103/188 (54%), Gaps = 15/188 (7%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHP 200 PIG P+ Y+LD +M+ V G GE+ + G+ LARGY+ G RF+ +P + Sbjct: 3449 PIGRPVGERTAYVLDLDMQPVPIGRVGELYIGGYGLARGYLGRAGLTAERFVADPFD--G 3506 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP-CVDNCVVLC 374 N +LYRTGD LD G I Y GRAD QVKIRG R++L E++ + + D VV+ Sbjct: 3507 NGGRLYRTGDLVRWLDDGNIEYIGRADHQVKIRGFRIELGEIEACIRELTGLTDVAVVVR 3566 Query: 375 YGVESSNPEILAFVT-------INPEARMSA---KNIEAELTSSLTDYMIP-QVIEIETV 521 G + P++ A+V + P + SA ++ +L L +YM+P ++ ++ + Sbjct: 3567 EG--AGGPQLAAYVAPKETTGMVAPVRKGSAGLGSTLKQQLVRRLPEYMVPAHIVILDKL 3624 Query: 522 PVLVNGKV 545 P L +GK+ Sbjct: 3625 PRLPSGKL 3632 >UniRef50_Q50857 Cluster: Saframycin Mx1 synthetase B; n=1; Myxococcus xanthus|Rep: Saframycin Mx1 synthetase B - Myxococcus xanthus Length = 1770 Score = 107 bits (256), Expect = 2e-22 Identities = 62/178 (34%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGK-DPHRFIHNPHNTH 197 V IG P++N VY+LD ++ V G GE+ + G +ARGY+ R + RF+ +P Sbjct: 1479 VSIGRPVANTQVYVLDRHLAPVPVGVRGELFIGGAGVARGYLGRPRMTAERFLPDPFREA 1538 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YRTGD +G + + GRAD QVK+RG R++ +E++ A+ P V VV+ Sbjct: 1539 PG-ARMYRTGDIVRYRAEGSLEFLGRADHQVKVRGFRIEFEEIETALRNHPAVREAVVVA 1597 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 G + ++A+V ++ + L L DYM+P V + +E +P+ NGKV Sbjct: 1598 RGT-GAERHLVAYVVLSARGESLVTELREHLRGRLPDYMVPGVFVMMEVLPLTPNGKV 1654 Score = 37.5 bits (83), Expect = 0.20 Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 1/105 (0%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMR-CVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 V G + + + ++D R + G GE+ V G ++A+GY + Sbjct: 390 VSCGTVVPDEQILVVDPETRTALPPGHIGEIWVRGPSVAQGYWLRPEETARTFQARLAGG 449 Query: 201 NFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV 335 A RTGD G L G + +GR + IRG Q+++ V Sbjct: 450 TEAPWLRTGDLGFLHDGELFVSGRRKDLLVIRGRNYYPQDLELTV 494 >UniRef50_A4C379 Cluster: Non-ribosomal peptide synthetase, terminal component; n=1; Pseudoalteromonas tunicata D2|Rep: Non-ribosomal peptide synthetase, terminal component - Pseudoalteromonas tunicata D2 Length = 3345 Score = 107 bits (256), Expect = 2e-22 Identities = 65/185 (35%), Positives = 105/185 (56%), Gaps = 10/185 (5%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-- 188 +VPIG PI N +Y+LD+ + + +G GE+ + G LARGY+ + RFI NP Sbjct: 3045 SVPIGKPIQNIQLYILDDELNLLPQGACGELHIGGDGLARGYLNRPELTQERFIANPFYQ 3104 Query: 189 -NTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 + +LY+TGD + G I Y GR D QVKIRG R++L E+++ V+ +D+ Sbjct: 3105 AEEGNSSERLYKTGDLVRYKEDGNIEYMGRLDHQVKIRGFRIELGEIEYQVAQHKQIDSA 3164 Query: 363 VVLCYGVESSNPEILAF-VTINPEARMS--AKNIEAELTSSLTDYMIP-QVIEIETVPVL 530 +V+ ++ N ++A+ T+ EA +++AEL + L +YM+P VI + P+ Sbjct: 3165 LVVAQADKAGNQRLIAYGKTVQAEASKEDVIASLKAELAAVLPEYMVPANVILVSEWPLT 3224 Query: 531 VNGKV 545 NGK+ Sbjct: 3225 PNGKI 3229 Score = 106 bits (255), Expect = 3e-22 Identities = 64/185 (34%), Positives = 105/185 (56%), Gaps = 10/185 (5%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-- 188 +VPIG PI N +Y+LD+ + + +G GE+ + G LARGY+ + RFI NP Sbjct: 861 SVPIGKPIQNIQLYILDDELNLLPQGACGELHIGGDGLARGYLNRPELTQERFIANPFYQ 920 Query: 189 -NTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 + +LY+TGD + G I Y GR D QVKIRG R++L E+++ V+ +D+ Sbjct: 921 AEEGNSSERLYKTGDLVRYKEDGNIEYMGRLDHQVKIRGFRIELGEIEYQVAQHKQIDSA 980 Query: 363 VVLCYGVESSNPEILAFV-TINPEARMS--AKNIEAELTSSLTDYMIP-QVIEIETVPVL 530 +V+ ++ N ++A+ T+ +A +++AEL + L +YM+P VI + P+ Sbjct: 981 LVVAQADKAGNQRLIAYAKTVQADASKEDVIASLKAELAAVLPEYMVPANVILVSEWPLT 1040 Query: 531 VNGKV 545 NGK+ Sbjct: 1041 PNGKI 1045 Score = 103 bits (248), Expect = 2e-21 Identities = 64/183 (34%), Positives = 100/183 (54%), Gaps = 9/183 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197 + IG P+ + ++ LLDE++ V +G GE+ VAG LARGY+ + RFI NP+ Sbjct: 1957 ITIGKPLRDQHILLLDESLNLVPKGCAGEIYVAGAGLARGYLNREALSAERFIANPYYHE 2016 Query: 198 PNF---AKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 +LY+ GD D +G + Y GR D QVKIRGHR++L EV+ ++ + VD+ + Sbjct: 2017 AGAWLGERLYKAGDLARYDAEGELHYLGRLDDQVKIRGHRIELGEVESRITQLEMVDSAL 2076 Query: 366 VLCYGVESSNPEILAFVTINPEARMS--AKNIEAELTSSLTDYMIPQVI-EIETVPVLVN 536 VL + +++A+V + + ++ L+ L YM+P VI I P+ N Sbjct: 2077 VLALPGVDAQLQLVAYVKVIDTFKEGDWQAQLKQTLSQQLQAYMLPSVIVPITQWPLTNN 2136 Query: 537 GKV 545 GKV Sbjct: 2137 GKV 2139 >UniRef50_P45745 Cluster: Dimodular nonribosomal peptide synthetase; n=25; Bacillus|Rep: Dimodular nonribosomal peptide synthetase - Bacillus subtilis Length = 2378 Score = 107 bits (256), Expect = 2e-22 Identities = 62/177 (35%), Positives = 98/177 (55%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI N VY+LD ++ V G GE+ +AG LARGY D RF+ +P+ P Sbjct: 771 PIGKPIWNTQVYVLDNGLQPVPPGVVGELYIAGTGLARGYFHRPDLTAERFVADPYG--P 828 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD G + Y GRAD Q+KIRG R++L E+D ++ P ++ V+ Sbjct: 829 PGTRMYRTGDQARWRADGSLDYIGRADHQIKIRGFRIELGEIDAVLANHPHIEQAAVVVR 888 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + + A+V +A + + + +SL DYM+P +E++ +P+ NGK+ Sbjct: 889 EDQPGDKRLAAYVV--ADAAIDTAELRRYMGASLPDYMVPSAFVEMDELPLTPNGKL 943 Score = 95.5 bits (227), Expect = 7e-19 Identities = 62/176 (35%), Positives = 94/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG I + VY+LDE ++ V G GE+ V+G LARGY+ G RFI +P P Sbjct: 1846 IGCGIPDLGVYVLDERLQPVPPGVAGELYVSGAGLARGYLGRPGLTSERFIADPFG--PP 1903 Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++YRTGD L G + Y GRAD QVKIRG R++L E++ A+ P +++ V+ Sbjct: 1904 GTRMYRTGDVARLRADGSLDYVGRADHQVKIRGFRIELGEIEAALVQHPQLEDAAVIVRE 1963 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + + A+V I E + L DYM+P + ++ +P+ NGK+ Sbjct: 1964 DQPGDKRLAAYV-IPSEETFDTAELRRYAAERLPDYMVPAAFVTMKELPLTPNGKL 2018 >UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces filamentosus|Rep: Peptide synthetase 1 - Streptomyces filamentosus (Streptomyces roseosporus) Length = 5830 Score = 106 bits (255), Expect = 3e-22 Identities = 63/178 (35%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNTH 197 VP+G P N Y+LD + V +G GE+ +AG LARGYV P RF+ +P Sbjct: 757 VPLGRPTLNRRGYVLDPALEPVPDGTTGELYLAGEGLARGYVAAPGPTAERFVADPFG-- 814 Query: 198 PNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +++YRTGD G +L + GRAD QVK+RG R++L EV A++ +P V VL Sbjct: 815 PPGSRMYRTGDLVRRRSGGMLEFVGRADGQVKLRGFRIELGEVQAALTALPGVRQAGVLI 874 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +P ++ ++ P A A + A L +L +M+P ++ + +P+ NGK+ Sbjct: 875 REDRPGDPRLVGYIVPAPGAEPDAGELRAALARTLPPHMVPWALVPLPALPLTSNGKL 932 Score = 101 bits (243), Expect = 8e-21 Identities = 63/178 (35%), Positives = 98/178 (55%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHP 200 PIG P+++ VY+LDE +R V G GE+ VAG LARGY+ RF+ +P++ Sbjct: 4464 PIGRPLADLQVYVLDERLRPVPPGTVGEMYVAGAGLARGYLGRPALTAERFVADPNSR-- 4521 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 + +LYRTGD + G + Y GR D QVKIRG R++L E++ A+ T V VVL Sbjct: 4522 SGGRLYRTGDLAKVRPDGGLEYVGRGDRQVKIRGFRIELGEIEAALVTHAGVVQAVVLVR 4581 Query: 378 GVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 ++ + ++A V P + + L ++L YM+P ++ +P+ NGK+ Sbjct: 4582 DEQTDDQRLVAHVVPALPHRAPTLAELHEHLAATLPAYMVPSAYRTLDELPLTANGKL 4639 Score = 101 bits (242), Expect = 1e-20 Identities = 67/179 (37%), Positives = 95/179 (53%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V IG P+ N V++LD +R V G GE+ VAG LARGY+ G RF+ P Sbjct: 1816 VAIGRPLRNTRVFVLDGGLRAVPVGVVGELHVAGEGLARGYLGQPGLTAERFVACPFGDA 1875 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G++ + GR D QVK+RG R++L EV+ AV+ P VD VV+ Sbjct: 1876 GE--RMYRTGDLVRWRADGMLEFVGRVDDQVKVRGFRIELGEVEAAVAACPGVDRSVVVV 1933 Query: 375 YGVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+VT EA A I L YM+P V+ ++ +P+ NGKV Sbjct: 1934 REDRPGDRRLVAYVTAAGDEAEGLAPLIVETAAGRLPGYMVPSAVVVLDEIPLTPNGKV 1992 Score = 99.1 bits (236), Expect = 6e-20 Identities = 63/180 (35%), Positives = 92/180 (51%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T IG P+ N V++LD + V G PGE+ +AG LARGY+R D RF+ NP Sbjct: 5525 TPGIGTPLDNWRVHILDAALGPVPPGVPGEIHIAGSGLARGYLRRPDLTAERFVANPF-- 5582 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD G G + + GR D QVK+RG R++L +V+ A++ P V Sbjct: 5583 APG-ERMYRTGDLGRFRPDGTLEHLGRVDDQVKVRGFRIELGDVEAALARHPDVGRAAAA 5641 Query: 372 CYGVESSNPEILAFVTINPEAR-MSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+V P R A + + L DYM+P + + T+P NGK+ Sbjct: 5642 VRPDHRGQGRLVAYVVPRPGTRGPDAGELRETVRELLPDYMVPSAQVTLTTLPHTPNGKL 5701 Score = 96.7 bits (230), Expect = 3e-19 Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P + +++++LD +R GE+ VAG LARGY+ D RF+ P + Sbjct: 3393 VPIGRPFTGHHLFVLDPALRLTPPDTIGELYVAGDGLARGYLGRPDLTAERFVACPFRS- 3451 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD G + + GRAD QVKIRG R++L EV+ AV+ P V + + Sbjct: 3452 PG-ERMYRTGDLARWRSDGTLEFIGRADDQVKIRGFRIELGEVEAAVAAHPHVARAIAVV 3510 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+VT + + +S+ + + L YM+P V+ ++ +P+ NGKV Sbjct: 3511 REDRPGDQRLVAYVTGSDPSGLSSA-VTDTVAGRLPAYMVPSAVVVLDQIPLTPNGKV 3567 >UniRef50_Q0S1Z9 Cluster: Non-ribosomal peptide synthetase; n=1; Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide synthetase - Rhodococcus sp. (strain RHA1) Length = 5496 Score = 106 bits (255), Expect = 3e-22 Identities = 61/178 (34%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P +N + Y+LD + V GE+ VAG LARGY RF+ NP+ Sbjct: 3890 VPIGTPQTNCHAYVLDHRLHPVPVAVVGELYVAGVQLARGYHNRPALTAERFVANPYG-- 3947 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD G + Y GR D QVK+RGHR++L E++ ++T P + + V Sbjct: 3948 PPGERMYRTGDLVRWHPDGTLEYLGRRDLQVKLRGHRIELGEIEATLTTHPDITHAAVTV 4007 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + + ++ +V AR+ + A + L DYM+P I + + +P+ +GKV Sbjct: 4008 HHDHHTGDRLVGYVVPRDGARLDPARVRALVADRLPDYMVPSPITVLDRLPLTASGKV 4065 Score = 103 bits (247), Expect = 3e-21 Identities = 61/178 (34%), Positives = 91/178 (51%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P +N + Y+LD + V GE+ VAG LARGY RF+ NP+ Sbjct: 4951 VPIGTPQTNCHAYVLDHRLHPVPVAVVGELYVAGVQLARGYHNRPALTAERFVANPYG-- 5008 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD G + Y GR D QVK+RGHR++L E++ ++T P + + V Sbjct: 5009 PPGERMYRTGDLVRWHPDGTLEYLGRRDLQVKLRGHRIELGEIEATLTTHPDITHAAVTV 5068 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + + ++ +V A + I L DYM+P I I + +P+ NGK+ Sbjct: 5069 HHDHHTGDRLVGYVAPRNGAPLDPTTIHTFAADRLPDYMVPTPITILDALPLTTNGKI 5126 Score = 101 bits (243), Expect = 8e-21 Identities = 58/178 (32%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 + IG PI + Y+LD+ +R V G E+ +AG LARGY RF+ NP+ Sbjct: 778 ITIGGPIRGTHAYVLDDRLRPVPTGVTAELHLAGIQLARGYHNRPALTAERFVANPYG-- 835 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD G + + GR D Q+K+RGHR++L E++ ++T P + + V Sbjct: 836 PPGERMYRTGDLVRWHPDGTLEFLGRRDLQIKLRGHRIELAEIEATLTTHPDITHAAVTV 895 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + + +++A+V P A++ + A L DYM+P I + + +P+ NGK+ Sbjct: 896 HKGPVTE-QLVAYVVPTPGAQIDPARVRAFAADRLPDYMLPDPITVLDRLPLTPNGKI 952 Score = 101 bits (243), Expect = 8e-21 Identities = 58/178 (32%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 + IG PI + Y+LD+ +R V G E+ +AG LARGY RF+ NP+ Sbjct: 2336 ITIGGPIRGTHAYVLDDRLRPVPTGVTAELHLAGIQLARGYHNRPALTAERFVANPYG-- 2393 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD G + + GR D Q+K+RGHR++L E++ ++T P + + V Sbjct: 2394 PPGERMYRTGDLVRWHPDGTLEFLGRRDLQIKLRGHRIELAEIEATLTTHPDITHAAVTV 2453 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + + +++A+V P A++ + A L DYM+P I + + +P+ NGK+ Sbjct: 2454 HKGPVTE-QLVAYVVPTPGAQIDPARVRAFAADRLPDYMLPDPITVLDRLPLTPNGKI 2510 >UniRef50_A5FI40 Cluster: Amino acid adenylation domain; n=1; Flavobacterium johnsoniae UW101|Rep: Amino acid adenylation domain - Flavobacterium johnsoniae UW101 Length = 1992 Score = 106 bits (255), Expect = 3e-22 Identities = 65/179 (36%), Positives = 104/179 (58%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVPIG PI+N VY+LDE + + EG GE+ + G LARGY+ + +FI NP+ Sbjct: 841 TVPIGKPIANTEVYILDEYLNLLPEGAIGEIYITGAGLARGYLNRPELTAEKFIPNPYK- 899 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +Y+TGD G L G I Y GR D QVKIRG+R++L+E++ +S V + VV+ Sbjct: 900 --EGEIMYKTGDLGKWLADGNIEYTGRIDEQVKIRGYRIELEEIEKHLSLQDEVKHAVVV 957 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E+ + + L ++ + + + ++A L L +YMIP +++E++ + +GKV Sbjct: 958 V--KENQDDKYLVAYYVS-DVELDKRKLQAALGKILPEYMIPGYFVQVESILMNTSGKV 1013 >UniRef50_A3DGP4 Cluster: Amino acid adenylation domain; n=1; Clostridium thermocellum ATCC 27405|Rep: Amino acid adenylation domain - Clostridium thermocellum (strain ATCC 27405 / DSM 1237) Length = 1833 Score = 106 bits (255), Expect = 3e-22 Identities = 62/185 (33%), Positives = 101/185 (54%), Gaps = 6/185 (3%) Frame = +3 Query: 9 HIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN 182 H VPIG P+ N Y+LD++ + V G GE+ + G +ARGY+ + +FI N Sbjct: 804 HAGSVVPIGRPLPNVKAYVLDKHRQPVPIGVVGELYIGGAGVARGYINEPEMTKQKFIPN 863 Query: 183 PHNTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359 P + P+ + +YRTGD L G I + GR D Q+KIRG+R+D +E++HA+ V + Sbjct: 864 PFHPGPS-SYMYRTGDLVRYLPDGNIEFLGRIDRQIKIRGYRIDPEEIEHAIKEHSVVRD 922 Query: 360 CVVLCYGVESSNPEILAFVTIN--PEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVL 530 VV G + +++A++ ++ E + I L L +YM P + +++P+ Sbjct: 923 AVVTVRGNSEKSNKLVAYLVLDKKAEGNLDISEIRRYLKKKLPEYMRPSSFTVLDSIPLN 982 Query: 531 VNGKV 545 NGKV Sbjct: 983 TNGKV 987 >UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular organisms|Rep: Peptide synthetase - Mycobacterium smegmatis Length = 5990 Score = 106 bits (254), Expect = 4e-22 Identities = 67/178 (37%), Positives = 100/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 VPIG P+ ++LDE +R V G GE+ +AG + GYV G RF+ P Sbjct: 5268 VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAGRGVGVGYVGRSGLTGTRFVACPFG-E 5326 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YRTGD D G + Y GRAD QVKIRG+R++L E+ A+S + VD VV+ Sbjct: 5327 PG-ARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIA 5385 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++ ++T + + +ELT+ L YM+P V+ +ET+P+ VNGK+ Sbjct: 5386 REDRPGDKRLVGYITGTADPAAA----RSELTNRLPAYMVPAAVVTLETLPLTVNGKL 5439 Score = 98.7 bits (235), Expect = 8e-20 Identities = 60/177 (33%), Positives = 94/177 (53%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG P+ +++LD+ +R EG GE+ VAG +A GY+ D RF+ P Sbjct: 3775 PIGAPVPGAALFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETG 3834 Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD G + Y GRAD QVKIRG+R++L E+ A++ + VD VV+ Sbjct: 3835 E--RMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAR 3892 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++ ++T + L SL YM+P V+ ++T+P+ VNGK+ Sbjct: 3893 EDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKL 3945 Score = 93.1 bits (221), Expect = 4e-18 Identities = 63/179 (35%), Positives = 95/179 (53%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T PIGVP+ + ++LD +R V G GE+ VAG LA GY+ D RF+ P Sbjct: 2270 TSPIGVPLEHLSFFVLDGWLRQVPVGVVGELYVAGEGLACGYISRSDLTSTRFVACPFGA 2329 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A++YRTGD G + Y GRAD QVKIRG+R++L EV A+ + V+ V+ Sbjct: 2330 -PG-ARMYRTGDLVRWGADGQLQYVGRADEQVKIRGYRIELGEVHAALVGLDGVEQAAVI 2387 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++ +VT + A L + YM+P ++ +E++P+ VNGK+ Sbjct: 2388 AREDRPGDKRLVGYVT----GAVDPVKARAALAERIPAYMVPAAIVVMESLPLTVNGKL 2442 Score = 84.6 bits (200), Expect = 1e-15 Identities = 56/180 (31%), Positives = 93/180 (51%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHN 191 + VPIG + +++LD +R V G GE+ VAG + GY+ G RF+ P Sbjct: 757 VVVPIGSALPRTALFVLDPWLRPVPTGVAGELYVAGDGVTCGYIGRSGLTASRFVPCPFG 816 Query: 192 THPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 P A++YRTGD + G + Y GRAD QVKIRG+R++L EV A++ + V++ Sbjct: 817 -EPG-ARMYRTGDLVRWGRDGQLEYLGRADEQVKIRGYRIELGEVQSALAALDGVESAAA 874 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + ++ ++T +I AEL L YM+P ++ + +P+ + K+ Sbjct: 875 IMREDRPGDRRLVGYIT----GTADPVDIRAELADRLPPYMVPTAIVVLPALPLTSSNKL 930 >UniRef50_Q4C9F4 Cluster: Non-ribosomal peptide synthase:Amino acid adenylation; n=1; Crocosphaera watsonii WH 8501|Rep: Non-ribosomal peptide synthase:Amino acid adenylation - Crocosphaera watsonii Length = 1569 Score = 106 bits (254), Expect = 4e-22 Identities = 62/181 (34%), Positives = 97/181 (53%), Gaps = 7/181 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD+ ++ G PGE+ + G +ARGY D RFI +P Sbjct: 828 VPIGRPITNTEIYILDQYLQPTPIGVPGELYIGGLGVARGYFNRPDLTAERFIPHPFTRR 887 Query: 198 ---PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 P+ ++LY+TGD L G I Y GR D QVKIRG RV+L E++ + P V + Sbjct: 888 QPTPSSSRLYKTGDLARYLSDGTIEYLGRIDDQVKIRGFRVELGEIEGILRQHPQVKEAI 947 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542 + + P ++A+V A + + + L YM+P + + +++ P+ VNGK Sbjct: 948 AVVQEDNNKIPRLVAYVV----AESEIEELRQFTSDKLPGYMVPTLFLTMDSFPLTVNGK 1003 Query: 543 V 545 + Sbjct: 1004 I 1004 >UniRef50_Q1D3L3 Cluster: Non-ribosomal peptide synthase; n=1; Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide synthase - Myxococcus xanthus (strain DK 1622) Length = 2091 Score = 106 bits (254), Expect = 4e-22 Identities = 64/180 (35%), Positives = 98/180 (54%), Gaps = 6/180 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VP+G P++N +++LD GE GE+ + G LARGY+R D F+ +P + Sbjct: 331 VPMGAPVANTRLHVLDARGHLAAPGEVGELLIGGVGLARGYLRRPDLTAAAFVPDPFSEE 390 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LYRTGD + G + + GR D QVK+RG+RV+L E++ A+ P + VV+ Sbjct: 391 PG-ARLYRTGDLVRRMPDGTLQFLGRRDHQVKVRGYRVELGEIEAALLGHPGLREAVVVV 449 Query: 375 YGVESSNPEILAFV--TINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 G ++A+V N + + A L SL DYM+P V I ++ +P+ GKV Sbjct: 450 RGEGEDEHRLVAYVVPARNAVEPLELTALRAFLERSLPDYMVPAVFIPLDGLPLTPTGKV 509 Score = 85.4 bits (202), Expect = 8e-16 Identities = 57/179 (31%), Positives = 93/179 (51%), Gaps = 7/179 (3%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 +G I N +Y+LD R V G GE+ + G +ARGY+ RF+ +P + Sbjct: 1395 LGHAIDNTELYVLDTGGRPVPVGVAGELFIGGEGVARGYLGQPALTAERFVPDPFSARLG 1454 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LYRTGD + G + + GR D QVK+RGHR++L E++ ++ P V+ VV+ Sbjct: 1455 -ARLYRTGDLVRWREGGGLEFLGRIDHQVKVRGHRIELAEIETTLAGHPAVEQAVVVARV 1513 Query: 381 VESSNPEILAFVTINPEARMSAKNIEA---ELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+ P +N++A L+ L M+P V + + P+ NGKV Sbjct: 1514 HAAEDVRLVAYFI--PRTGQDGRNVQALRQWLSERLPGPMVPTVFVPLACFPLTPNGKV 1570 >UniRef50_Q0PH94 Cluster: MassC; n=1; Pseudomonas fluorescens|Rep: MassC - Pseudomonas fluorescens Length = 3774 Score = 106 bits (254), Expect = 4e-22 Identities = 63/179 (35%), Positives = 100/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VP+G PISN +Y+LD + + G GE+C+ G +A+GY+ + +F+ NP N Sbjct: 2937 SVPVGRPISNTQIYVLDAQLHLLPLGVSGEICIGGDGVAQGYLNRPELTAEKFVQNPFN- 2995 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A LYRTGD G G++ GR D QVKIRG R++L E++ ++T + VVL Sbjct: 2996 -PG-ALLYRTGDLGRWSADGLLECIGRNDDQVKIRGFRIELGEIEARMATFAGIREGVVL 3053 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ T E + +++ A L + L YM+P + +E +P+ NGKV Sbjct: 3054 AREDVPGDKRLVAYFTWAGEP-VGIESVRAYLQAHLPAYMVPSAFVALEHLPLTANGKV 3111 Score = 99.5 bits (237), Expect = 4e-20 Identities = 62/177 (35%), Positives = 98/177 (55%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+N VY+LD + R V G GE+ V G +ARGY+ + RF+ +P N Sbjct: 866 IGKPIANAKVYVLDPHQRPVPLGVAGELYVGGKGVARGYLNRPELTAERFVRDPFNA--- 922 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++YRTGD L G + Y GR D QVKIRG R++L E++ ++ +P + V + Sbjct: 923 -GRMYRTGDLVRWLPDGTLDYLGRNDDQVKIRGVRIELGEIETQLNQLPGILEAVAVV-- 979 Query: 381 VESSNPEILAFVTINPEA-RMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++A+ T NP+ ++ I A L + L DYM+P ++++ +P+ NGK+ Sbjct: 980 ---REERLVAYFTENPQLDPLTLAEIRAHLVAHLPDYMVPVAFMKLDALPLTANGKL 1033 Score = 91.5 bits (217), Expect = 1e-17 Identities = 57/177 (32%), Positives = 94/177 (53%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI+N +Y+LD ++ V G GE+ +AG +ARGY+ + RF+ +P Sbjct: 1909 PIGKPIANTRLYVLDGQLQPVPLGVVGELFIAGVQVARGYLNRPELTAERFLDDPFTP-- 1966 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD L G + Y GR D QVKIRG R++L E+ ++ P V V+ Sbjct: 1967 --GRMYRTGDVSRYLPDGTLEYLGRNDDQVKIRGLRIELGEIQARLTEHPAVQEAAVI-- 2022 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A+ T P +++ A L L ++M+P + ++ +P+ NGK+ Sbjct: 2023 ---AREQRLIAYYTGVPS---EVESLRAHLLQHLPEFMLPASFVHLQVLPLSPNGKL 2073 >UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin synthetase C-related non- ribosomal peptide synthetase module; n=8; Proteobacteria|Rep: Arthrofactin synthetase/syringopeptin synthetase C-related non- ribosomal peptide synthetase module - Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) Length = 8646 Score = 106 bits (254), Expect = 4e-22 Identities = 62/179 (34%), Positives = 98/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PISN +Y+LD++ V G GE+ + G + RGY+ + RF+ + + Sbjct: 1900 SVPIGRPISNTQIYILDQHGDPVPIGVAGEIHIGGVQVGRGYLNRPELTAERFVEDRFSG 1959 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A+LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+ Sbjct: 1960 EAG-ARLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHAAVRDAAVI 2018 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ +A + A+ + L + L DYM+P + +E +P+ NGK+ Sbjct: 2019 AREDAPGDQRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLERLPLTPNGKL 2075 Score = 105 bits (252), Expect = 7e-22 Identities = 61/179 (34%), Positives = 100/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PISN +Y+LD++ V G GE+ + G + RGY+ + RF+ + + Sbjct: 7277 SVPIGRPISNTQIYILDQHGDPVPIGVAGEIHIGGVQVGRGYLNRPELTAERFVEDRFSG 7336 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A+LYRTGD G L+ G I Y GR D QVKIRG R++L E++ +S V + V+ Sbjct: 7337 EAG-ARLYRTGDLGRWLEDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVI 7395 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+ +A + A+ + L + L DYM+P + ++ +P+ NGK+ Sbjct: 7396 AREDVAGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTPNGKL 7452 Score = 103 bits (246), Expect = 4e-21 Identities = 60/179 (33%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++P+G PISN +Y+LD V G GE+ + G +ARGY+ + RF+ + + Sbjct: 4056 SIPLGRPISNTRIYILDAYGDPVPIGVAGEIYIGGAGVARGYLNRPELTAERFVEDRFSG 4115 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A+LYRTGD G L+ G I Y GR D QVKIRG R++L E++ +S V + V+ Sbjct: 4116 EAG-ARLYRTGDLGRWLEDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVI 4174 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+ +A + A+ + L + L DYM+P + ++ +P+ NGK+ Sbjct: 4175 AREDVAGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTPNGKL 4231 Score = 102 bits (245), Expect = 5e-21 Identities = 61/176 (34%), Positives = 95/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PISN +Y+LDE+ G GE+ + G +ARGY+ + RF+ + + Sbjct: 813 IGRPISNTQIYILDEHGEPAPIGVAGEIYIGGAGVARGYLNRPELTAERFVEDQFSGEAG 872 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+ Sbjct: 873 -ARLYRTGDLGRWLSDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHAGVRDVAVIARE 931 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ +A + A+ + L + L DYM+P + +E +P+ NGK+ Sbjct: 932 DAPGDQRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLERLPLTPNGKL 985 Score = 102 bits (245), Expect = 5e-21 Identities = 61/179 (34%), Positives = 98/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++P+G PISN +Y+LD V G GE+ + G +ARGY+ + RF+ + + Sbjct: 5132 SIPLGRPISNTRIYILDAYGDPVPIGVAGEIYIGGAGVARGYLNRPELTAERFVEDRFSG 5191 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A+LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+ Sbjct: 5192 EAG-ARLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDVAVI 5250 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+ +A + A+ + L + L DYM+P + +E +P+ NGK+ Sbjct: 5251 AREDVAGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLERLPLTPNGKL 5307 Score = 100 bits (239), Expect = 3e-20 Identities = 60/176 (34%), Positives = 95/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG PISN +Y+LDE+ G GE+ + G +ARGY+ RF+ + + Sbjct: 2982 IGRPISNTQIYILDEHGEPAPIGVAGEIYIGGAGVARGYLNRPALTAERFVEDRFSGEAG 3041 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+ Sbjct: 3042 -ALLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVIARE 3100 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+ +A + A+ + L + L DYM+P + ++ +P+ +NGK+ Sbjct: 3101 DVAGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTLNGKL 3154 Score = 100 bits (239), Expect = 3e-20 Identities = 60/176 (34%), Positives = 95/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG PISN +Y+LDE+ G GE+ + G +ARGY+ RF+ + + Sbjct: 6214 IGRPISNTQIYILDEHGEPAPIGVAGEIYIGGAGVARGYLNRPALTAERFVEDRFSGEAG 6273 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+ Sbjct: 6274 -ALLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVIARE 6332 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+ +A + A+ + L + L DYM+P + ++ +P+ +NGK+ Sbjct: 6333 DVAGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTLNGKL 6386 Score = 97.9 bits (233), Expect = 1e-19 Identities = 59/176 (33%), Positives = 93/176 (52%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PISN +Y+LD G GE+ + G +ARGY+ + RF+ + + Sbjct: 8360 IGRPISNTQIYILDAYGEPAPIGVAGEIYIGGAGVARGYLNRPELTAERFVEDRFSGEAG 8419 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LYRTGD G L G I Y GR D QVKIRG R++L E++ +S V + V+ Sbjct: 8420 -ARLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHAAVRDVAVIARE 8478 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ +A + A+ + L + L DYM+P + ++ +P+ NGK+ Sbjct: 8479 DGPGDKRLVAYYV--SDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTPNGKL 8532 >UniRef50_A3I9A7 Cluster: Peptide synthetase; n=1; Bacillus sp. B14905|Rep: Peptide synthetase - Bacillus sp. B14905 Length = 1055 Score = 106 bits (254), Expect = 4e-22 Identities = 57/177 (32%), Positives = 98/177 (55%), Gaps = 2/177 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 ++PIG PI+N +Y+++++ + GE+C+AG LA GY+ + PH P Sbjct: 376 SIPIGRPIANYEMYVVNKDEQLCPVHVTGELCIAGAGLAAGYLHQPEKTAEAFVPHLFKP 435 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 + K+YRTGD +L GVI + GR DSQ+K+RG R++L E++ +S P + VV+ Sbjct: 436 D-QKMYRTGDLVRLLPSGVIEFVGRKDSQIKVRGFRIELGEIETVLSNHPIIQESVVIAK 494 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + A+ T ++ + + L + L DYM+P+ IE+ +P+ GK+ Sbjct: 495 KMSDGQNHLFAYYTAANGIQLEEQVLRDYLNNLLPDYMVPERFIELLEMPLSPTGKI 551 >UniRef50_Q83Z53 Cluster: Putisolvin synthetase; n=3; Bacteria|Rep: Putisolvin synthetase - Pseudomonas putida Length = 3066 Score = 105 bits (253), Expect = 5e-22 Identities = 58/177 (32%), Positives = 99/177 (55%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG P+ N +Y+LD + + V G PGE+ + G +ARGY+ RF+ +P Sbjct: 684 IGRPVDNARLYVLDAHQQPVALGVPGELYIGGAGVARGYLNRPALTAERFLDDPFVATAG 743 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++YRTGD L G + Y GR D QVKIRG R++L E++ +S + +D VVL Sbjct: 744 -GRMYRTGDLVRWLPDGTLDYLGRNDDQVKIRGVRIELGEIESRLSALAGIDEAVVLARE 802 Query: 381 VESSNPEILAFVTINPEAR-MSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + P ++A+ T + + ++ + + A+L + L +YM+P + ++ +P+ NGK+ Sbjct: 803 DQPGQPRLVAYFTAQADVKPLTPEGLRAQLQAHLPEYMVPVAFVALQALPLTANGKL 859 Score = 99 bits (238), Expect = 3e-20 Identities = 64/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI N VY+LD + V +G GE+ + G +A GY+ + RFI +P + Sbjct: 1730 VPIGRPIGNTQVYVLDAWQQPVPQGVVGELYIGGDGVALGYLNRPELTAQRFIDDPFSQQ 1789 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LYRTGD G + GR D QVKIRG+R++L E++ ++ P V VV+ Sbjct: 1790 PG-ARLYRTGDLVRWQPDGQLECLGRNDDQVKIRGYRIELGEIEQQLALAPGVGEVVVMA 1848 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E ++A+ T EA + A + A L L +YM+P + + +P+ NG V Sbjct: 1849 VPGEQGPLRLVAWFT-RLEAALQATELRAFLRGRLPEYMVPSAFVALPRMPLNNNGXV 1905 Score = 46.0 bits (104), Expect = 6e-04 Identities = 26/60 (43%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Frame = +3 Query: 168 RFIHNPHNTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTI 344 R +H H A+LYRTGD L G I Y GR D QVKI G R++L E+ ++ I Sbjct: 2830 RTLHRRPVQHSPRARLYRTGDLARHLSDGNIEYLGRNDDQVKIHGLRIELGEIQAGLTRI 2889 >UniRef50_Q70P97 Cluster: MelC protein; n=4; Cystobacteraceae|Rep: MelC protein - Melittangium lichenicola Length = 1323 Score = 105 bits (253), Expect = 5e-22 Identities = 62/179 (34%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNT 194 ++P G P+ N Y+LD+ + + PGE+ + G +ARGY R + RFI +P Sbjct: 826 SIPYGRPMLNQRFYVLDDALASRPDYVPGELFIGGVGVARGYFRDDVRTAERFIVHPKTN 885 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LYRTGD G L G I + GR D QVK+ GHR++L E++ A+ P + VV Sbjct: 886 E----RLYRTGDLGRFLPGGDIEFLGRKDFQVKVAGHRIELGEIEAALLRHPALREAVVA 941 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 G S+ + V +A SA+++++ L ++L YM+P + + +E +P+ NGKV Sbjct: 942 APGERSARRLVAYVVVAEGQAVPSAESLQSFLGATLPQYMVPGIFVHLERLPLSSNGKV 1000 >UniRef50_A4JPB0 Cluster: Amino acid adenylation domain; n=1; Burkholderia vietnamiensis G4|Rep: Amino acid adenylation domain - Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderiacepacia (strain R1808)) Length = 533 Score = 105 bits (253), Expect = 5e-22 Identities = 66/179 (36%), Positives = 96/179 (53%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPHNT 194 TVPIG P++ V +LD + + VR GE GE+ G LA GY+ + R F+ +PH+ Sbjct: 319 TVPIGRPVTGTTVCVLDASGQPVRPGEVGELYAGGIGLALGYLNDPEKTRAVFVDDPHDR 378 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 KLYRTGD G + GR D QVKIRG+RV +++V ++T V++ +V Sbjct: 379 D---RKLYRTGDLVREGHDGAYEFIGRVDRQVKIRGYRVSVEQVQQVLATADDVEDAIVD 435 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIE-TVPVLVNGKV 545 E ++AFV + + + L L YMIP VIE++ +P+ VNGKV Sbjct: 436 VGRDELGEKRLVAFVQSSRDPAEVRAAVRRHLGRHLASYMIPDVIEVQVALPLTVNGKV 494 >UniRef50_A4FE18 Cluster: Non-ribosomal peptide synthetase; n=3; Actinomycetales|Rep: Non-ribosomal peptide synthetase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 1083 Score = 105 bits (253), Expect = 5e-22 Identities = 68/179 (37%), Positives = 102/179 (56%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHR--FIHNPHNTH 197 VP+G I N +VY++DEN+ V G PGE+ +G + RGYV D R F+ +PH Sbjct: 556 VPLGPAIPNVHVYVVDENLDPVPLGAPGEIVFSGVCVGRGYVNDPDRTRLAFLADPH--R 613 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV-DNCVVL 371 P +LYR+GD G L +G + + GR DSQVKIRG R+++ E+++ + +P V D VV+ Sbjct: 614 PG-QRLYRSGDHGRWLPEGKLEFLGRRDSQVKIRGFRIEIGEIENTLLRVPGVRDGAVVV 672 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + S + AF + E + A + L SL +YM+P V E +P+ NGK+ Sbjct: 673 AERADLSK-HLAAFYSAPGE--LDAGMLRDTLAESLPEYMVPPVFHWRERLPLTANGKI 728 >UniRef50_A4BRH4 Cluster: Probable peptide synthetase protein; n=3; Bacteria|Rep: Probable peptide synthetase protein - Nitrococcus mobilis Nb-231 Length = 2660 Score = 105 bits (253), Expect = 5e-22 Identities = 66/186 (35%), Positives = 102/186 (54%), Gaps = 12/186 (6%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPH--- 188 +PIG PI+N +Y+LD + V G GE+ + G LARGY +G F+ NP Sbjct: 1871 IPIGRPIANTRLYVLDARLEPVPPGVVGELYIGGAGLARGYAQGPALSAAAFVPNPFPKA 1930 Query: 189 ---NTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVD 356 P ++LYRTGD GV+ Y GR D QVK+RG RV+L E++ A+ ++P V Sbjct: 1931 GLAGAGPG-SRLYRTGDLARWRADGVLEYVGRIDHQVKLRGFRVELAEIEVALESLPAVR 1989 Query: 357 NCVVLCYGVESSNPEILAFV--TINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPV 527 VV S ++ +V T+ P + ++A+L +L +YM+P Q++ +E +P+ Sbjct: 1990 EAVVTAREAPSGK-RLVGYVVPTVAPGRAGLTEELQAQLKEALPEYMVPAQLVVLEKLPL 2048 Query: 528 LVNGKV 545 NGK+ Sbjct: 2049 TPNGKL 2054 Score = 95.1 bits (226), Expect = 9e-19 Identities = 58/179 (32%), Positives = 96/179 (53%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +PIG P N +Y+LD ++ V G GE+C+AG + RGY+ + F+ +P+ Sbjct: 813 LPIGRPTDNTRLYVLDGQLQPVPVGVTGELCIAGAGVGRGYLHDPARTAQAFVPHPYAQT 872 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +LYR+GD GV+ Y GR+D QVK+RG R++L E++ + V VV+ Sbjct: 873 PG-ERLYRSGDLARWRADGVLEYVGRSDHQVKVRGFRIELGEIEARLLEHQGVREAVVVV 931 Query: 375 YGVESSNPEILAFVTINPEARMSAKN-IEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 S + V EA + ++A L ++ +YM+P Q++ +E +P+ NGK+ Sbjct: 932 REAPSGKHLVGYVVPTALEAGAELGDALKAHLKEAIPEYMVPGQIVVLEQLPLTPNGKL 990 >UniRef50_A1ZSC1 Cluster: Mixed type I polyketide synthase-peptide synthetase, putative; n=1; Microscilla marina ATCC 23134|Rep: Mixed type I polyketide synthase-peptide synthetase, putative - Microscilla marina ATCC 23134 Length = 2045 Score = 105 bits (253), Expect = 5e-22 Identities = 64/178 (35%), Positives = 102/178 (57%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197 +PIG P N +Y+L+E + + GE GE+ +AG + RGY + + +F+ NP N Sbjct: 1504 IPIGQPYQNTQLYVLNEQLEQLPVGEIGELYIAGDGVTRGYWKNEALTQEKFVDNPFN-- 1561 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +LY++GD + +G ++ GR D QVKIRG RV+L E++ +S P V VV+ Sbjct: 1562 PG-TRLYKSGDKAQWNAEGQLVCLGRVDQQVKIRGFRVELGEIEQVLSAHPLVLQAVVVA 1620 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + + N ++ AFVT + ++ A+ + L L +YMIP E ++ P+ VNGKV Sbjct: 1621 QKI-NQNQQLKAFVTF--KVQVKAEALSVHLKERLPEYMIPANFELVDKFPLTVNGKV 1675 >UniRef50_A1G2S8 Cluster: Amino acid adenylation domain; n=1; Salinispora arenicola CNS205|Rep: Amino acid adenylation domain - Salinispora arenicola CNS205 Length = 2125 Score = 105 bits (253), Expect = 5e-22 Identities = 70/178 (39%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P+ N +++D V G PGE+CV+G LARGYV D RF NP+ Sbjct: 774 VPIGTPLRNMRAHVVDRWDELVPLGVPGELCVSGVGLARGYVGRGDLTAERFRPNPYARV 833 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P + YRTGD D GV+ + GR D QVKIRG RV+ EV+ AV T P V VV Sbjct: 834 PG-ERWYRTGDLVRWRDDGVLEFVGRVDEQVKIRGVRVEPAEVEAAVRTHPDVGEAVVAA 892 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E + E++A+ +S +++ A L L MIP + ++ +P+ NGKV Sbjct: 893 RRGELGDLELVAYTVPANGTPVSLESLAAHLADVLPAPMIPSNHVGLDVLPLTPNGKV 950 Score = 102 bits (244), Expect = 6e-21 Identities = 59/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG P+S Y+LD + V G PGE+C+ G LARGY+ + RF+ +PH+ Sbjct: 1832 MPIGRPVSGTRGYVLDAKLMPVPVGVPGELCLGGVRLARGYLNRPELTADRFVPDPHSGE 1891 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A+LYRTGD G I + GR D QVK+RG R++L E++ A++ P V VV Sbjct: 1892 RG-ARLYRTGDLVRWRPDGTIEFIGRIDQQVKVRGFRIELGEIEAALAEHPAVQASVVAV 1950 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 V +++ +V + A L + +YM+P + + ++ +P+ + KV Sbjct: 1951 REVGPGEKQLVGYVVPRVGPVPDVAGLRAHLRDRVPEYMVPARWVTLDALPLTASKKV 2008 >UniRef50_P40806 Cluster: Putative polyketide synthase pksJ; n=9; Bacteria|Rep: Putative polyketide synthase pksJ - Bacillus subtilis Length = 5045 Score = 105 bits (253), Expect = 5e-22 Identities = 64/177 (36%), Positives = 103/177 (58%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+N +Y+ D + V G PGE+C+AG +A+GY + ++ RFI NP P Sbjct: 1468 IGRPIANTQIYITDSQLAPVPAGVPGELCIAGDGVAKGYYKKEELTDSRFIDNPF--EPG 1525 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +KLYRTGD L G I Y GR D+QVKIRG R++L +++ +S P + CVV+ Sbjct: 1526 -SKLYRTGDMARWLTGGRIEYIGRIDNQVKIRGFRIELGDIESRLSEHPGILECVVV--- 1581 Query: 381 VESSNPEILAFVTI-NPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + A+ T + A ++A+ + + ++L YM+P I+++ +P+ NGK+ Sbjct: 1582 --ADMDNLAAYYTAKHANASLTARELRHFVKNALPAYMVPSYFIQLDHMPLTPNGKI 1636 Score = 49.2 bits (112), Expect = 6e-05 Identities = 47/187 (25%), Positives = 85/187 (45%), Gaps = 13/187 (6%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 V IG PI + +++++ V EGE G V+G ++ GY + D + + Sbjct: 374 VEIGSPIPGFSMRIVNDHNELVEEGEIGRFQVSGLSVTSGYYQRPDLNESVFTEDG---- 429 Query: 204 FAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN-----CVV 368 + TGD G L G + GR + I G ++ AV +P ++ C V Sbjct: 430 ---WFETGDLGFLRNGRLTITGRTKDAIIINGINYYSHAIESAVEELPEIETSYTAACAV 486 Query: 369 LCYGVESSNPEILAFVT---INPEARMS--AKNIEAELTSSL---TDYMIPQVIEIETVP 524 G S++ + FVT +N E +MS +NI++ ++ + +Y++P ++ E +P Sbjct: 487 R-LGQNSTDQLAIFFVTSAKLNDE-QMSQLLRNIQSHVSQVIGVTPEYLLP--VQKEEIP 542 Query: 525 VLVNGKV 545 GK+ Sbjct: 543 KTAIGKI 549 >UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1; Streptomyces avermitilis|Rep: Non-ribosomal peptide synthetase - Streptomyces avermitilis Length = 3686 Score = 105 bits (252), Expect = 7e-22 Identities = 65/178 (36%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P+ N VY+LD ++ V G GE+ V G +ARGY D RF+ +P+ Sbjct: 2882 VPIGRPLPNMRVYVLDSALQPVPVGVTGELYVGGTGVARGYAGRPDLTAERFLPDPYAAE 2941 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LYRTGD L G + + GR D QVKIRG+RV+L EV ++ P V + V Sbjct: 2942 PG-ARLYRTGDLVRHLPDGNVEFLGRVDDQVKIRGYRVELGEVQAVLAEHPAVRDAFVTV 3000 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++ + T A + + A L DYM+P + +E +P+ NGKV Sbjct: 3001 HEPVPGDRRLVGYWTPAAGAGARPEELAAHCAVRLPDYMVPSAFVALEALPLNANGKV 3058 Score = 101 bits (242), Expect = 1e-20 Identities = 57/176 (32%), Positives = 101/176 (57%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 +G P+++ VYLLD + + V G PGE+ V G +ARGY+ + RF+ +P+ P Sbjct: 802 VGHPLADLRVYLLDADRQLVPVGVPGEIHVGGPGVARGYLNRPELTAERFVPDPYG--PA 859 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++LY++GD L G + + GR D QVKIRG R++L E++ A++ P V + VVL Sbjct: 860 GSRLYKSGDLARRLPDGSLEFLGRIDDQVKIRGFRIELGEIETALAAHPQVRDAVVLVRE 919 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ T + + ++ + L + L +YM+P + ++ +P+ NGK+ Sbjct: 920 DTPGDKRLVAYTTPAADQAPAPGDLRSHLAARLPEYMVPAAFVALDALPLTTNGKL 975 Score = 93.5 bits (222), Expect = 3e-18 Identities = 60/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG P+ N VY+LD ++ V G GE+ V G +ARGY D RF+ +P+ T Sbjct: 1839 LPIGRPLPNMRVYVLDPALQPVPVGVTGELYVGGTGIARGYAGRPDLTAERFLPDPYGTE 1898 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YRTGD G + + GR D QVKIRG+RV+L E+ ++ P + + Sbjct: 1899 PG-ARVYRTGDLVRQRPDGNVEFLGRVDDQVKIRGYRVELGEIQAVLTAHPGIRDAF--- 1954 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545 V + + E+ + A A+ + L L DYM+P + ++ +P+ NGK+ Sbjct: 1955 --VTTVDGELAGYY-----APAGAEGVREHLADRLPDYMVPATLTALDALPLNANGKI 2005 >UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Rep: Iturin A synthetase A - Bacillus subtilis Length = 3982 Score = 105 bits (252), Expect = 7e-22 Identities = 61/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P +N +Y+ D + V G GE+ ++G +ARGY D +F+ NP+ Sbjct: 3261 VPIGTPAANTDIYVADASRNLVPIGVIGEIYISGPGVARGYWNRPDLTEEKFVENPYV-- 3318 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P AK+Y++GD L G ++Y GR D QVKIRGHR++L E++ A+ V V Sbjct: 3319 PG-AKMYKSGDLAKRLKDGNLVYIGRVDEQVKIRGHRIELGEIEAAMHNAEAVQKAAVTV 3377 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E ++ A+ + ++A + +L+S L DYM+P + +E +P+ NGK+ Sbjct: 3378 KEEEDGLKQLCAYYV--SDKPIAAAQLREQLSSGLPDYMVPSYFVRLEHMPLTSNGKI 3433 >UniRef50_Q70C52 Cluster: Non-ribosomal peptide synthase; n=1; Xanthomonas albilineans|Rep: Non-ribosomal peptide synthase - Xanthomonas albilineans Length = 1959 Score = 105 bits (252), Expect = 7e-22 Identities = 64/178 (35%), Positives = 100/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VP+G PI+N V++LDE +R + G GEV + + GY R G RFI NP+ Sbjct: 343 VPVGRPIANTKVHVLDEQLRPLPPGIMGEVHIESLGITHGYWRQGGLTAARFIANPYG-- 400 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++LYRTGD +LD G + GR D +VK+RG+RVD+++V+ A++ V V+ Sbjct: 401 PPGSRLYRTGDMARLLDNGTLELLGRRDYEVKVRGYRVDVRQVEKALAAHLQVAEAAVIG 460 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + S PE+LA+V + + ++ + L L YM+P + + +P L NGK+ Sbjct: 461 WPQGSPTPELLAYV-VPRQGVLNLDELRKLLQERLPTYMLPTRFQSLPALPRLPNGKL 517 Score = 105 bits (252), Expect = 7e-22 Identities = 64/178 (35%), Positives = 100/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VP+G PI+N V++LDE +R + G GEV + + GY R G RFI NP+ Sbjct: 1394 VPVGRPIANTKVHVLDEQLRPLPPGIMGEVHIESLGITHGYWRQGGLTAARFIANPYG-- 1451 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++LYRTGD +LD G + GR D +VK+RG+RVD+++V+ A++ V V+ Sbjct: 1452 PPGSRLYRTGDMARLLDNGTLELLGRRDYEVKVRGYRVDVRQVEKALAAHLQVAEAAVIG 1511 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + S PE+LA+V + + ++ + L L YM+P + + +P L NGK+ Sbjct: 1512 WPQGSPTPELLAYV-VPRQGVLNLDELRKLLQERLPTYMLPTRFQSLPALPRLPNGKL 1568 >UniRef50_Q6YK39 Cluster: Bacillomycin D synthetase C; n=4; Bacillus|Rep: Bacillomycin D synthetase C - Bacillus subtilis Length = 2619 Score = 105 bits (252), Expect = 7e-22 Identities = 61/182 (33%), Positives = 105/182 (57%), Gaps = 5/182 (2%) Frame = +3 Query: 15 FLTVPIGVPISNNYVYLLDENMRCVRE-GEPGEVCVAGFNLARGYVRGKD--PHRFIHNP 185 + ++PIG PISN +Y+L ++ ++ G GE+C+AG LARGY+ + +F+++P Sbjct: 580 YASIPIGKPISNIQLYILHADLEHMQPIGVAGELCIAGDGLARGYLNRPELTAEKFVNHP 639 Query: 186 HNTHPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 + ++YRTGD L G I Y GR D QVKIRG+R+++ EV+ A +P + Sbjct: 640 IASGE---RIYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIEIGEVEGAFFQLPVIKEA 696 Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539 +V+ ++ + A+ T + ++A + EL+ L YMIP +++E +P+ NG Sbjct: 697 IVIAREIDGET-SLCAYYT--AQHALTAGELREELSRQLPSYMIPAYFVQLEEMPLTFNG 753 Query: 540 KV 545 K+ Sbjct: 754 KI 755 Score = 94.3 bits (224), Expect = 2e-18 Identities = 61/176 (34%), Positives = 94/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI Y+LDE G PGE+ VAG LARGY+ + +F+ +P Sbjct: 2100 IGQPIPTLQAYILDEYQHIQVMGIPGELYVAGEGLARGYLNRPELTAEKFVEHPFAAGE- 2158 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 K+Y+TGD L G I Y GR D QVKIRG+R+++ EV+ A+ V VV+ Sbjct: 2159 --KMYKTGDVARWLPDGNIEYLGRIDHQVKIRGYRIEIGEVEAALLQSESVKEAVVIAIE 2216 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E S ++ A+ ++ + ++ ++ L + L YMIP +++E +P+ NGK+ Sbjct: 2217 EEGSK-QLCAY--LSGDDSLNTAQLKRHLLNKLPAYMIPAYFVQMEKMPITANGKI 2269 >UniRef50_Q4U445 Cluster: DszC; n=3; Proteobacteria|Rep: DszC - Polyangium cellulosum (Sorangium cellulosum) Length = 3795 Score = 105 bits (252), Expect = 7e-22 Identities = 63/176 (35%), Positives = 96/176 (54%), Gaps = 2/176 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 VPIG ISN +++LD +R V G G++ + G LARGY+ + R P P Sbjct: 1301 VPIGRAISNVEIHILDSALRPVPAGAEGDLYIGGVCLARGYLNRPELSRERFVPSPFDPG 1360 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LY TGD LD G I Y GR D+QVK+RG R++L E++ A+S V + VV Sbjct: 1361 -ARLYNTGDRARTLDDGNIEYLGRLDAQVKLRGFRIELGEIEAALSAHEAVQDAVVAVQD 1419 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + +P+++A++ + ++A L L DYM+P + I +PV +GK+ Sbjct: 1420 AHTEDPKLVAYLVTGGRPFPAPGALKAYLKERLPDYMVPNRFAPIAQIPVTAHGKL 1475 >UniRef50_Q44103 Cluster: Peptide-synthetase; n=1; Amycolatopsis mediterranei|Rep: Peptide-synthetase - Amycolatopsis mediterranei (Nocardia mediterranei) Length = 1324 Score = 105 bits (252), Expect = 7e-22 Identities = 67/176 (38%), Positives = 97/176 (55%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHPN 203 IG P+ + ++LDE +R G PGE+ + G LA GY G RF+ +P + P Sbjct: 656 IGTPLPHLSAHVLDEWLRPCPAGVPGELYIGGGALAHGYWGRAGLTAQRFLPDPFSPVPG 715 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LYRTGD L G + Y GR DSQVKIRG R++L E++HA+ P V C V + Sbjct: 716 -ARLYRTGDVARRLAGGGLEYVGRCDSQVKIRGFRIELGEIEHALGAHPAVGACAVTVH- 773 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + + A+VT P+ + A L SL ++MIP + + + +PV VNGK+ Sbjct: 774 ----DDRLAAYVTGGPD----HAELRAHLAKSLPEHMIPATVTVLDRLPVTVNGKL 821 >UniRef50_A7BRU4 Cluster: Non-ribosomal peptide synthetase; n=1; Beggiatoa sp. PS|Rep: Non-ribosomal peptide synthetase - Beggiatoa sp. PS Length = 1010 Score = 105 bits (252), Expect = 7e-22 Identities = 68/179 (37%), Positives = 104/179 (58%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 VPIG PI+N+ Y+ D E +C G+ GE+CVAG L+RGY+ D +F+ NP Sbjct: 327 VPIGKPIANSQAYIYDREGCQCP-VGQIGEICVAGEGLSRGYLNRPDLTVLKFVQNP--D 383 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +YRTGD G D+ G I ++GR+D+QVK+RGHR++L E+++ + + + VV Sbjct: 384 MPG-TLMYRTGDLGYWDRNGNIHFSGRSDNQVKLRGHRIELGEIENTLQQLRGIREIVVK 442 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +GV + + + T E +S+ I L L YM+P + + +E +PV NGKV Sbjct: 443 DWGV-GGDKYLCVYYTAARE--LSSNAIRIFLQERLPAYMVPSKFVWLEEMPVSWNGKV 498 >UniRef50_A4CG27 Cluster: Amino acid adenylation; n=2; Pseudoalteromonas tunicata D2|Rep: Amino acid adenylation - Pseudoalteromonas tunicata D2 Length = 340 Score = 105 bits (252), Expect = 7e-22 Identities = 64/185 (34%), Positives = 105/185 (56%), Gaps = 10/185 (5%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-- 188 +VPIG PI N +Y+LD+ + + +G GE+ + G LARGY+ + RFI NP Sbjct: 125 SVPIGKPIQNIQLYILDDELNLLPQGACGELHIGGDGLARGYLNRPELTQERFIANPFYQ 184 Query: 189 -NTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 + +LY+TGD + G I Y GR D QVKIRG R++L E+++ V+ +D+ Sbjct: 185 AEEANSSERLYKTGDLVRYKEDGNIEYMGRLDHQVKIRGFRIELGEIEYQVAQHKQIDSA 244 Query: 363 VVLCYGVESSNPEILAF-VTINPEARMS--AKNIEAELTSSLTDYMIP-QVIEIETVPVL 530 +V+ ++ N ++A+ T+ +A +++AEL + L +YM+P VI + P+ Sbjct: 245 LVVAQADKAGNQRLIAYGKTVQADAPKEDVITSLKAELAAVLPEYMVPANVILVSEWPLT 304 Query: 531 VNGKV 545 NGK+ Sbjct: 305 PNGKI 309 >UniRef50_A0YGI5 Cluster: Peptide synthetase; n=1; marine gamma proteobacterium HTCC2143|Rep: Peptide synthetase - marine gamma proteobacterium HTCC2143 Length = 1499 Score = 105 bits (252), Expect = 7e-22 Identities = 59/178 (33%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 + IG PI+N VY+LD+N+ + PGE+C+ G ++ GY + + RF+ TH Sbjct: 773 ITIGRPIANTQVYVLDDNLNPLPVSVPGELCIGGAGVSLGYHQRPALNDDRFV-----TH 827 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD L G I + GR D QVK+RG+R++L E++ A+ + V+ VV Sbjct: 828 PVLGRIYRTGDLAKALPNGEIQHLGRLDDQVKLRGYRIELGEIEMALKSCVEVEQAVVYL 887 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + ++A + + +I +L L YM+PQ + I +P+ NGKV Sbjct: 888 LNLGEQDVRVVACCVPVADRALETISIRKKLRECLPSYMVPQYFLSISKIPLTPNGKV 945 >UniRef50_A0UVJ0 Cluster: Amino acid adenylation domain; n=2; Clostridium cellulolyticum H10|Rep: Amino acid adenylation domain - Clostridium cellulolyticum H10 Length = 1499 Score = 105 bits (252), Expect = 7e-22 Identities = 60/180 (33%), Positives = 105/180 (58%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 ++VPIG+P N +Y+LD+N+ V GE+ V+G + RGY+ ++ RF+ NP Sbjct: 764 VSVPIGIPADNIQIYILDKNLNPVPVETIGELYVSGAGVTRGYLNREELTKERFVDNPFI 823 Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 +K+Y+TGD L G I+Y GR+D QVK+RG+R++L E+++ + + + + +V Sbjct: 824 KG---SKMYKTGDLAKHLHGGEIVYMGRSDYQVKLRGYRIELGEIENYLFSHNSITDAIV 880 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + E N + A++ + +S I L+S L DYM+P + ++++P+ NGKV Sbjct: 881 IDRNDEKGNKYLCAYIVSTTDLDIS--EIRMFLSSKLPDYMLPSHFVILQSLPLTSNGKV 938 >UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide synthetase protein; n=2; Proteobacteria|Rep: Probable non ribosomal peptide synthetase protein - Ralstonia solanacearum (Pseudomonas solanacearum) Length = 5953 Score = 105 bits (251), Expect = 9e-22 Identities = 63/178 (35%), Positives = 101/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD + V G GE+ + G +ARGY+ + RF+ NP + Sbjct: 1930 VPIGRPIANTQIYVLDAYRQPVPLGVTGEIYIGGAGVARGYLNRPELTAERFVVNPFHGE 1989 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G L G + Y GRAD+QVK+RG R++L E++ +S V VV Sbjct: 1990 GR-ERMYRTGDLGRWLPDGSLEYQGRADAQVKLRGFRIELGEIEARLSQCAGVSEAVVAM 2048 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+ ++ EA + A+ + +L +SL +YM+P + +E +P+ NGK+ Sbjct: 2049 REDVPGEQRLVAYY-VSGEA-IEAQTLREQLQASLPEYMVPAAYVRLEHLPLTPNGKL 2104 Score = 103 bits (247), Expect = 3e-21 Identities = 63/178 (35%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD + V G GEV + G +ARGY+ + RF+ NP + Sbjct: 3008 VPIGRPIANTQMYVLDAYRQPVPLGVTGEVYIGGAGVARGYLNRPELTAERFVENPFHGE 3067 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G L G + Y GRAD+QVK+RG R++L E++ + V VV Sbjct: 3068 GR-ERMYRTGDLGRWLPDGSLEYQGRADAQVKLRGFRIELGEIEARLLQCAGVSEAVVTV 3126 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+ ++ EA + A+ + +L S L +YM+P + +E +P+ NGK+ Sbjct: 3127 REDAPGEQRLVAYY-VSGEA-IEAQTLREQLQSRLPEYMVPAAYVRLERLPLTPNGKL 3182 Score = 101 bits (243), Expect = 8e-21 Identities = 62/183 (33%), Positives = 103/183 (56%), Gaps = 9/183 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI+N +Y+LD + V G GE+ V G + GY+ + RF+ NP + Sbjct: 870 IPIGRPIANTQIYVLDAYQQPVPLGVTGEIYVGGAGVGLGYLNRPELTAERFVVNPFHGE 929 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++Y+TGD G L G + Y GR D+QVK+RG R++L E++ ++S V VV+ Sbjct: 930 GR-ERMYKTGDLGRWLPDGSLEYQGRTDAQVKLRGFRIELGEIEASLSQCAGVSEAVVIV 988 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEA-----ELTSSLTDYMIPQV-IEIETVPVLVN 536 ++A+ ++ EA +S + IEA +L +SL +YM+P +++E +P+ N Sbjct: 989 REDTPGERRLVAYY-VSGEANVSGEAIEAQALREQLQASLPEYMVPAAYVKLERLPLTPN 1047 Query: 537 GKV 545 GK+ Sbjct: 1048 GKL 1050 Score = 101 bits (241), Expect = 1e-20 Identities = 61/176 (34%), Positives = 99/176 (56%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+N +Y+LD + V G GE+ + G +ARGY+ + RF+ NP + Sbjct: 4054 IGRPIANTQIYVLDAYRQPVPLGVTGEIYIGGAGVARGYLNRPELTAERFVVNPFHGEGR 4113 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++YRTGD G L G + Y GRAD+QVK+RG R++L E++ +S V VV Sbjct: 4114 -ERMYRTGDLGRWLPDGSLEYQGRADAQVKLRGFRIELGEIEARLSQCAGVSEAVVTMRE 4172 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+ ++ EA + A+ + +L +SL +YM+P + +E +P+ NGK+ Sbjct: 4173 DVPGEQRLVAYY-VSGEA-IEAQTLREQLQASLPEYMVPAAYVRLERLPLTPNGKL 4226 Score = 96.7 bits (230), Expect = 3e-19 Identities = 62/176 (35%), Positives = 98/176 (55%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG PI+N +Y+LD V G PGE+ V G +ARGY+ G RF+ +P + Sbjct: 5108 IGRPIANTQIYILDAYGAPVPIGVPGEIHVGGACVARGYLHRPGLTAERFVADPFHGDGR 5167 Query: 204 FAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD G G I+Y GR D QVK+RG R++ E++ ++ V VVL Sbjct: 5168 -ARMYRTGDLGCWQADGNIVYLGRNDHQVKLRGFRIEPGEIEARLAGCEGVREAVVLIRD 5226 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 P ++A+ + P A + A+ + A+L ++L YM+P + +E +P+ +GK+ Sbjct: 5227 DGVGEPRLVAYYS-GP-AALPAQALRAQLQAALPAYMVPAAYVYLERMPLTSSGKL 5280 >UniRef50_Q89T13 Cluster: Bll2237 protein; n=2; Bradyrhizobium|Rep: Bll2237 protein - Bradyrhizobium japonicum Length = 2154 Score = 105 bits (251), Expect = 9e-22 Identities = 59/178 (33%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VP+G P+ N +Y+LD N+ G GE+C+ G + RGY+ ++ RF+ +P Sbjct: 1410 VPVGAPLPNTQLYVLDANLEPQPVGVTGELCIGGAGVGRGYINDPAQNKQRFLPDPF-LR 1468 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++LYRTGD G I GRAD QVK+RG+R++L+E+++A++ P V +V Sbjct: 1469 QAASRLYRTGDLARRRADGTIECLGRADHQVKVRGYRIELKEIENALADHPSVRAGIVEP 1528 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 S + ++A + P +R+SA + L S L + IP + ++ VP+ +GK+ Sbjct: 1529 RREASGDVRLIAHIVARPGSRVSASELRDFLKSRLPGHAIPSAFLFMDQVPLNAHGKI 1586 Score = 50.4 bits (115), Expect = 3e-05 Identities = 39/166 (23%), Positives = 67/166 (40%), Gaps = 3/166 (1%) Frame = +3 Query: 57 VYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAK-LYRTGDF 233 + ++DE R + G GE+ + G N++RGY + T F +RTGD Sbjct: 357 IAVMDETGRALASGAHGEIVLRGANMSRGYYNDEAA---------TQAAFRDGWFRTGDL 407 Query: 234 GILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVESSNPEILA 410 G LD G + GR + G ++ EV+ + + P V V + A Sbjct: 408 GYLDADGYLFIVGRIKDVINRGGQKISPLEVEEVLLSHPAVLEAGVFAVPHPKLGENVAA 467 Query: 411 FVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545 V + + ++ + L Y +P +I + +P +GKV Sbjct: 468 VVVLRANSEATSDQLRKFARKRLAAYKVPSLIRSVAALPKGASGKV 513 >UniRef50_Q4ZV19 Cluster: Non-ribosomal peptide synthase:Amino acid adenylation; n=6; Pseudomonadaceae|Rep: Non-ribosomal peptide synthase:Amino acid adenylation - Pseudomonas syringae pv. syringae (strain B728a) Length = 2883 Score = 105 bits (251), Expect = 9e-22 Identities = 62/180 (34%), Positives = 101/180 (56%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNT 194 +VP+G P++N +LD + V E GE+ + G LA+GY+ RF+ +P Sbjct: 814 SVPVGQPLANGKARVLDAYLNPVAERVAGELYLGGRGLAQGYLGRAAMTAERFVPDPD-- 871 Query: 195 HPNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 N +LYR GD GV+ Y GRAD QVKIRG+RV+ EV + T+ V + VVL Sbjct: 872 -ANGQRLYRAGDRARWVDGVLEYLGRADDQVKIRGYRVEPGEVGQLLQTLENVADAVVLA 930 Query: 375 YGVESSNP--EILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +ES +++A+ A ++ +++ +L + L +Y++P Q++ +E +PV NGK+ Sbjct: 931 QPLESDETRLQLVAYCVAAAGASLNVESLRGQLAARLPEYLVPAQIMLLERLPVTANGKL 990 Score = 93.1 bits (221), Expect = 4e-18 Identities = 61/184 (33%), Positives = 98/184 (53%), Gaps = 8/184 (4%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHN 191 L+VPIG PI N ++LD+ + +G E+ + G LARGY RF+ +P + Sbjct: 2312 LSVPIGRPIDNLKTHILDDGLLPAAQGVAAELYLGGVGLARGYHNRAALTAERFVPDPFD 2371 Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 +LYRTGD D GVI YAGR D QVKIRG R++L E++ + V V Sbjct: 2372 EQGG-GRLYRTGDLARYRDAGVIDYAGRIDHQVKIRGLRIELGEIEARLHEHAAVREATV 2430 Query: 369 LCYGVESSNPEILAFVTINPEAR----MSAKNIEAELTSSLTDYMIP-QVIEIETVPVLV 533 + ++ + + LA + +A + + ++A L + + DYM+P + I+++P+ Sbjct: 2431 I--DIDGPSGKQLAAYLVPTDATEAPDVLRERLQAHLKAHVPDYMVPGYFVFIDSMPLTA 2488 Query: 534 NGKV 545 NGK+ Sbjct: 2489 NGKL 2492 >UniRef50_Q2JA66 Cluster: Amino acid adenylation; n=15; Bacteria|Rep: Amino acid adenylation - Frankia sp. (strain CcI3) Length = 4489 Score = 105 bits (251), Expect = 9e-22 Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P+ N V++LD ++ V G GE+ VAG LARGY G RF+ P + Sbjct: 772 VPIGRPMDNTRVFVLDRFLQPVPPGVTGELYVAGVGLARGYFGRPGLTGERFVACPFSGS 831 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G +G +++AGR D QVK+RG R++L EV+ + P V CVV+ Sbjct: 832 GE--RMYRTGDLGRWTGEGQLVFAGRVDGQVKVRGFRIELGEVEAVLGLYPGVGRCVVVV 889 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 E ++A+V + + I + L +YM+P V+ + +P+ GKV Sbjct: 890 REDEPGQKRLVAYVVASEGEALDTVQIRDFVAGLLPEYMVPAVVVVLSGLPLTGQGKV 947 Score = 99.1 bits (236), Expect = 6e-20 Identities = 61/176 (34%), Positives = 95/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 +G P+ Y+LDE +R V G GE+ VAG LARGY+ RF+ P Sbjct: 3965 VGGPLPGVRTYVLDEFLRPVPPGVVGELYVAGAGLARGYLNRPALTGERFVACPFGGSGE 4024 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++YRTGD G +++AGRAD+QVKIRG R++ E++ +S P VD V+ Sbjct: 4025 --RMYRTGDLARWTGDGGLVFAGRADAQVKIRGFRIEPGEIEAVLSGHPAVDQVAVVMRE 4082 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + ++A++ P + A I A + L +YM+P V+E+ +P+ NGK+ Sbjct: 4083 DQPGHRHLVAYLV--PHQEIGAAEIRAFVAGRLPEYMVPAVVVEVAELPLTANGKL 4136 Score = 91.9 bits (218), Expect = 9e-18 Identities = 60/178 (33%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI N +++LD +R V G GE+ +AG LARGYV RF+ P + Sbjct: 1828 VPIGGPIWNVRLFVLDGFLRPVPPGVVGELYIAGVGLARGYVGRSSLTGERFVACPFSGS 1887 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD GV++Y GR D+QVKIRG R++L EV+ ++ V V+ Sbjct: 1888 GE--RMYRTGDLVRWRGDGVLVYVGRVDAQVKIRGLRIELGEVEAVLAGDGAVGRVAVVV 1945 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + ++A+V + A + L +YM+P V+E+ +P+ ++GK+ Sbjct: 1946 REDQPGHRYLVAYVVAAAGRGVDAAGLREFAARRLPEYMVPAAVVELAELPLTLSGKL 2003 Score = 83.4 bits (197), Expect = 3e-15 Identities = 56/178 (31%), Positives = 93/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V +G PI+ Y+LD+ ++ V G GE+ +AG LARGY G RF+ P + Sbjct: 2885 VSLGTPIAGTRTYVLDDLLQPVPPGVVGELYLAGPGLARGYWARAGLTGERFVACPFSGS 2944 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YR+GD G +++ GRAD+Q+KIRG RV++ EV+ ++ P V VV+ Sbjct: 2945 GE--RMYRSGDLVRWTAAGELVFVGRADTQLKIRGFRVEVGEVEAVLAVFPGVTRVVVVA 3002 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++ +V + + AE L +Y++P V+ + +PV NGK+ Sbjct: 3003 REDRPGHRYLVGYVVPGDVDGRAVREFAAE---RLPEYLVPAGVVALPALPVTPNGKL 3057 >UniRef50_Q2JA64 Cluster: Amino acid adenylation; n=3; Actinomycetales|Rep: Amino acid adenylation - Frankia sp. (strain CcI3) Length = 4606 Score = 105 bits (251), Expect = 9e-22 Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P+ N V++LD ++ V G GE+ VAG LARGY G RF+ P + Sbjct: 767 VPIGRPMDNTRVFVLDRFLQPVPPGVTGELYVAGVGLARGYFGRPGLTGERFVACPFSGS 826 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G +G +++AGR D QVK+RG R++L EV+ + P V CVV+ Sbjct: 827 GE--RMYRTGDLGRWTGEGQLVFAGRVDGQVKVRGFRIELGEVEAVLGLYPGVGRCVVVV 884 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 E ++A+V + + I + L +YM+P V+ + +P+ GKV Sbjct: 885 REDEPGQKRLVAYVVASEGEALDTVQIRDFVAGLLPEYMVPAVVVVLSGLPLTGQGKV 942 Score = 105 bits (251), Expect = 9e-22 Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P+ N V++LD ++ V G GE+ VAG LARGY G RF+ P + Sbjct: 2300 VPIGRPMDNTRVFVLDRFLQPVPPGVTGELYVAGVGLARGYFGRPGLTGERFVACPFSGS 2359 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G +G +++AGR D QVK+RG R++L EV+ + P V CVV+ Sbjct: 2360 GE--RMYRTGDLGRWTGEGQLVFAGRVDGQVKVRGFRIELGEVEAVLGLYPGVGRCVVVV 2417 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 E ++A+V + + I + L +YM+P V+ + +P+ GKV Sbjct: 2418 REDEPGQKRLVAYVVASEGEALDTVQIRDFVAGLLPEYMVPAVVVVLSGLPLTGQGKV 2475 Score = 95.5 bits (227), Expect = 7e-19 Identities = 61/178 (34%), Positives = 92/178 (51%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG PI N V++LD ++ V G GE+ VAG +ARGY+ G RF+ P Sbjct: 3827 VPIGRPIRNARVFVLDSFLQPVPSGVVGELYVAGVGVARGYLNRPGLTAERFVACPFGG- 3885 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G ++Y GR DSQVK+RG+R++ EV+ ++ P V V+ Sbjct: 3886 ---GRMYRTGDLVRWSGAGQLVYVGRVDSQVKVRGYRIEPGEVEVVLAGCPGVGQVAVVV 3942 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 ++A+V + I + L +YM+P V+ + +P+ VNGKV Sbjct: 3943 REDLPGQRRLVAYVVPAGGVAVDTAGIRGFAAARLPEYMVPAVVVVLPVLPLTVNGKV 4000 >UniRef50_Q0SEB1 Cluster: Non-ribosomal peptide synthetase; n=2; Bacteria|Rep: Non-ribosomal peptide synthetase - Rhodococcus sp. (strain RHA1) Length = 2366 Score = 105 bits (251), Expect = 9e-22 Identities = 66/179 (36%), Positives = 98/179 (54%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHNT 194 VPIGV + Y+LD +R V G GE+ +AG ++ RGY R + P RFI +P Sbjct: 1815 VPIGVVDPGKHAYVLDHALRPVPPGVSGELYLAGDSVTRGY-RNQSPKTAERFIADPFAV 1873 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +++YRT D + G I + GRADSQVK+RG R++L E++ +S P V++ VV+ Sbjct: 1874 -PG-SRMYRTSDVVWWGRDGQIYFTGRADSQVKVRGFRIELNEIEAVLSGDPDVEHIVVV 1931 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ T P R+ + S L DYMIP I ++ P L NGK+ Sbjct: 1932 VREDRPGDQRLVAYATSVPGGRIDPDQLHRRAASRLPDYMIPAAFIAVDEFPTLPNGKL 1990 Score = 97.9 bits (233), Expect = 1e-19 Identities = 60/180 (33%), Positives = 94/180 (52%), Gaps = 6/180 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V IGVP+ + Y+L +R V G GE+ V+G L+ GY+ D RF+ +P Sbjct: 752 VDIGVPLGDLRTYVLGPGLRPVPPGVTGEIYVSGPGLSPGYLGRPDLTSGRFVADPF--A 809 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD D G + Y GR D Q+++RG+RV+L E+ A++ +P V V Sbjct: 810 PGGTRMYRTGDLARYDATGTLHYHGRIDDQIQLRGYRVELGEIGAAMTAVPDVQAAVATA 869 Query: 375 YGVESSNPEILAFVTINPEARMSA--KNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + I+ +V P A + + A L SL YM P ++ ++ +P+ NGKV Sbjct: 870 HEQAGGDQRIVGYVVPRPGGEHDAVEEQVRAHLVRSLPGYMTPSALVMLDRLPLTHNGKV 929 >UniRef50_Q9RFK5 Cluster: MtaG; n=4; Cystobacteraceae|Rep: MtaG - Stigmatella aurantiaca Length = 1750 Score = 105 bits (251), Expect = 9e-22 Identities = 62/179 (34%), Positives = 96/179 (53%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+PIG PI N +YLLD +++ V G PGE+ + G +ARGY+ + RFI +P Sbjct: 1191 TLPIGRPILNTQMYLLDRHLQPVPMGVPGELLIGGEGVARGYLDRPELTATRFIPDPFGA 1250 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LYRTGD L G I + GR D QVK+RG R++ E++ A+ P + V+ Sbjct: 1251 EPG-ARLYRTGDLARYLPDGRIEFLGRMDQQVKVRGVRIEPGEIESALRLHPEIRQAAVV 1309 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + A+V P+A+++ + L L MIP I ++ +P+ N K+ Sbjct: 1310 ARADAAGEVSLAAYVVAGPDAQVAPSELRRFLKDKLPVSMIPDHFIRLDALPLTPNKKL 1368 >UniRef50_Q847C8 Cluster: NdaB; n=32; Cyanobacteria|Rep: NdaB - Nodularia spumigena Length = 1299 Score = 105 bits (251), Expect = 9e-22 Identities = 64/178 (35%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD ++ V G PGE+ + G LARGY+ + +FI NP Sbjct: 798 VPIGRPIANTQIYILDSQLQPVPIGIPGELHIGGIPLARGYLNQPELTAQKFIPNPFGN- 856 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 KLY+TGD L G I Y GR D+QVK+RG R++L E++ + T P V VV+ Sbjct: 857 ---GKLYKTGDLARYLPDGNIEYLGRIDNQVKLRGLRIELGEIESVLDTHPQVGQTVVIL 913 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + N +++A+V + + ++ + L L YMIP + + P+ NGK+ Sbjct: 914 REDIAENKQLVAYV-LRKDQSLTPGELRRFLQDKLPGYMIPSAFVILLDFPLNPNGKI 970 >UniRef50_Q4CA71 Cluster: Amino acid adenylation; n=1; Crocosphaera watsonii WH 8501|Rep: Amino acid adenylation - Crocosphaera watsonii Length = 1049 Score = 105 bits (251), Expect = 9e-22 Identities = 66/180 (36%), Positives = 101/180 (56%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 L+VPIG+PI N VY+L+ ++ + G GE+ + G LARGY+ D F+ NP Sbjct: 760 LSVPIGLPIDNIQVYVLNAQLQLLPVGVVGELYLGGEGLARGYLNKPDLTAENFVPNPFK 819 Query: 192 THPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 A+LYRTGDF + G + Y GR D+QVKIRG R++L E++ +S P + CVV Sbjct: 820 AG---ARLYRTGDFVRYQEDGNVEYVGRIDNQVKIRGVRLELGEIEAILSQHPDIIACVV 876 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 L + +LA++ + +S + + L + +Y IP V I +E+ P+ NGK+ Sbjct: 877 LAKEFAPGDRRLLAYIQTSQTEDIS-EELRQFLGERIPNYGIPSVFITLESFPLTNNGKL 935 >UniRef50_Q211M6 Cluster: Amino acid adenylation; n=1; Rhodopseudomonas palustris BisB18|Rep: Amino acid adenylation - Rhodopseudomonas palustris (strain BisB18) Length = 2315 Score = 105 bits (251), Expect = 9e-22 Identities = 65/179 (36%), Positives = 95/179 (53%), Gaps = 3/179 (1%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTH 197 L++PIG PI N+ YLLD R + G GE+ V G LA GY+ + P Sbjct: 782 LSIPIGTPIPNSTAYLLDPAGRPLPPGLVGEIWVGGDGLALGYMGDAELTAERFRPDLFA 841 Query: 198 P-NFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A++YRTGD G G I++ GRAD QVKIRG RV+L E++ ++ P V ++ Sbjct: 842 PAGEARMYRTGDLGRWRPDGNIVFLGRADKQVKIRGFRVELGEIEAMLALHPAVGGATII 901 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 S + +++A+VT P ++A + L L M+PQ I + +P+ NGKV Sbjct: 902 APRRASGDRDLVAYVTPKPGTALTATELRNYLQERLPRQMLPQAYAILDRLPLTANGKV 960 >UniRef50_Q0B1F5 Cluster: Amino acid adenylation domain; n=1; Burkholderia ambifaria AMMD|Rep: Amino acid adenylation domain - Burkholderia cepacia (strain ATCC 53795 / AMMD) Length = 1304 Score = 105 bits (251), Expect = 9e-22 Identities = 62/175 (35%), Positives = 94/175 (53%), Gaps = 2/175 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 +P+G PI N ++YLLDE+ EG GE+CV+G LARGYV G+D + + Sbjct: 564 LPVGRPIHNTHLYLLDEHGALAPEGCTGEICVSGIALARGYV-GRDDLTAAAFVDHPFES 622 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LYRTGD G+ L G + GR D QVKIRG+R+++ E++ A+ V + +V Sbjct: 623 GERLYRTGDLGVWLPDGNLEVTGRRDMQVKIRGYRIEMGEIEAALRQHADVADAIVF--- 679 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGK 542 V P+ V A S + L L ++M+P ++ +E +P+ NGK Sbjct: 680 VREDTPQHRQLVACVETATASVAGLREYLKERLPEFMVPGSIVTLERLPLTPNGK 734 >UniRef50_Q08MR4 Cluster: Linear gramicidin synthetase subunit D; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Linear gramicidin synthetase subunit D - Stigmatella aurantiaca DW4/3-1 Length = 336 Score = 105 bits (251), Expect = 9e-22 Identities = 62/177 (35%), Positives = 95/177 (53%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200 PIG PISN Y+LD+ M V G GE+ + G +LARGY+ +F+ +P +T P Sbjct: 27 PIGRPISNAQAYVLDKGMNPVPVGVSGELFIGGDSLARGYLDRPALTAEKFLPHPFSTQP 86 Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++LYRTGD G + + GR D QVKIRG R++L E++ ++ P V VV+ Sbjct: 87 G-SRLYRTGDLVRWSAAGELEFLGRVDQQVKIRGFRIELGEIEAVLAQHPAVREAVVVVR 145 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 +++ + EAR S + L L + M+P ++ +E +PV NGK+ Sbjct: 146 ESAPEVKQLVGYAVAQGEARPSKAELRTYLRERLPEPMVPSAIVLLEALPVTPNGKL 202 >UniRef50_A6LQ10 Cluster: Amino acid adenylation domain; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Amino acid adenylation domain - Clostridium beijerinckii NCIMB 8052 Length = 4034 Score = 105 bits (251), Expect = 9e-22 Identities = 57/179 (31%), Positives = 97/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++P G+P+SN Y+L+ + G GE+C+ G LA GY+ +D FI+ Sbjct: 1442 SIPYGMPLSNQSFYVLNYENQICHIGVMGELCIGGLGLAEGYLNDEDKTTESFIN----- 1496 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 H +LY+TGD+G+L K G I + GR D Q+KI G+R++L E+++ + V N VV+ Sbjct: 1497 HKELGRLYKTGDYGVLHKEGYIEFFGRKDQQIKINGYRLELGEIENCILEYEGVRNSVVV 1556 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++ + A++ E +S + + L DYM+P + ++ +P+ NGKV Sbjct: 1557 DRTHDNGRKYLCAYIV--GEKEISTTELREYIVELLPDYMVPSYFVMVDEIPLTANGKV 1613 Score = 103 bits (247), Expect = 3e-21 Identities = 56/177 (31%), Positives = 94/177 (53%), Gaps = 2/177 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 ++P G+P++N Y+L+ N GE+ + G LA GY+ ++ +N HP Sbjct: 2503 SIPYGIPLANQKFYVLNYNKDICPVEVIGELYIGGDGLAEGYMNDEEK---TNNAFINHP 2559 Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 + +LY TGD+G+L + G I + GR D Q+KIRG+RV+L E+ + + N VV+ Sbjct: 2560 DLGRLYNTGDYGVLHREGYIEFFGRKDQQIKIRGYRVELGEIQSGILEYKGIKNAVVVDK 2619 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E+ + A++ E +S + L L DYM+P + ++ +P+ NGKV Sbjct: 2620 THENGRKYLCAYIV--GEKEVSITGVREYLEELLPDYMVPSYFVMVDEIPLTANGKV 2674 Score = 102 bits (245), Expect = 5e-21 Identities = 54/177 (30%), Positives = 96/177 (54%), Gaps = 2/177 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 ++P G+P++N Y+L+ G GE+ + G LA GY+ ++ +N HP Sbjct: 3565 SIPYGMPLANQKFYVLNYEKEVCPIGIAGELYIGGEGLAEGYMNDEEK---TNNAFINHP 3621 Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 + +LY TGD+G++ + G I + GR D Q+KIRG+RV+L E+++ + + N VV+ Sbjct: 3622 DLGRLYNTGDYGVMSREGYIEFLGRKDHQIKIRGYRVELGEIENRILEHQSIKNVVVIDR 3681 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + A+V + +S + L ++ DYMIP + ++ +P+ NGKV Sbjct: 3682 SHSNGRKYLCAYVV--SDVDISVGELREHLGKTVPDYMIPSYFVILDKIPLTANGKV 3736 Score = 36.3 bits (80), Expect = 0.46 Identities = 40/177 (22%), Positives = 72/177 (40%), Gaps = 6/177 (3%) Frame = +3 Query: 33 GVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFAK 212 G PI + +V + D+ + + G V V G N+ Y + R T + Sbjct: 373 GTPIKDCFVRISDDTGNILGDDCIGHVQVTGKNIINNYYTEEATARSF-----TSDGWLI 427 Query: 213 LYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGV--- 383 TGD G L+ G + GRA + + G + +++ I ++ V G+ Sbjct: 428 ---TGDIGFLENGHLTITGRAKDMIIVNGQNFYVNDIERVAEGIEQIEFGKVAACGIFDS 484 Query: 384 ESSNPEILAFVTIN---PEARMSAKNIEAELTSSLTDYMIPQVIEIETVPVLVNGKV 545 +S + + + FV N E I+ EL+ + I +VI + +P +GK+ Sbjct: 485 KSQSEKAVIFVENNEPIDEFVSLLLKIKNELSYKM-GIEISRVIPVREIPKTGSGKI 540 >UniRef50_A1G7W6 Cluster: Amino acid adenylation domain; n=2; Salinispora|Rep: Amino acid adenylation domain - Salinispora arenicola CNS205 Length = 1347 Score = 105 bits (251), Expect = 9e-22 Identities = 63/179 (35%), Positives = 95/179 (53%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 ++P G + ++LD + R GEPGE+ + G LARGY+ DP + H HP Sbjct: 907 SIPYGRALRAQSFHILDPDGRPCPVGEPGELFIGGDGLARGYIG--DPEQTAHR-FARHP 963 Query: 201 NFA-KLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD G G I + GR D QVKIRGHR++L E++ A+ P + C+V Sbjct: 964 LLGERLYRTGDLGRWRTDGNIEFLGRVDRQVKIRGHRIELGEIEAALGRHPALRQCIVAA 1023 Query: 375 YGVESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 P + A+V +A +A + L L DYM+P + + ++++PV NGK+ Sbjct: 1024 VRGADERPRLAAYVVPKAGDAVPTADELAGTLRERLPDYMVPSKFLVLDSLPVTPNGKI 1082 >UniRef50_UPI000045C11E Cluster: COG1020: Non-ribosomal peptide synthetase modules and related proteins; n=3; Nostoc punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide synthetase modules and related proteins - Nostoc punctiforme PCC 73102 Length = 2671 Score = 104 bits (250), Expect = 1e-21 Identities = 66/187 (35%), Positives = 101/187 (54%), Gaps = 15/187 (8%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN----PH- 188 IG PISN Y+LD+N++ V G PGE+ + G LA+GY+ D RFI++ P+ Sbjct: 1913 IGRPISNTQAYILDQNLQPVPIGVPGELHLGGAGLAQGYLNRPDLTQERFINSKFKIPYG 1972 Query: 189 ------NTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP 347 N+ +LY+TGD L G I Y GR D+QVKIRG R++L E++ ++ P Sbjct: 1973 NAKVVQNSKLESERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIETVLNENP 2032 Query: 348 CVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVP 524 V VV+ + ++A++ + E + + LTS L DYMIP + + +P Sbjct: 2033 AVFQAVVIAREDDPGVKRLVAYLVLKQEQTPTVTELRQFLTSKLPDYMIPAAFVFLAALP 2092 Query: 525 VLVNGKV 545 + NGK+ Sbjct: 2093 MTPNGKI 2099 Score = 90.2 bits (214), Expect = 3e-17 Identities = 64/195 (32%), Positives = 99/195 (50%), Gaps = 23/195 (11%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP- 200 IG I+N VY+LD+ ++ V G PGE+ + G +LA GY+ + +FI NP N Sbjct: 376 IGRAIANTQVYILDQYLQPVPIGVPGELHIGGDSLALGYLNRPELTQEKFIPNPFNNSKF 435 Query: 201 ----------NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP 347 +KLY+TGD L G I Y GR D+QVKIRG R++L EV+ +S P Sbjct: 436 KIPYGNAKGVQNSKLYKTGDLACYLPDGNIEYLGRIDNQVKIRGFRIELGEVETTLSQHP 495 Query: 348 CVDNCVVL--------CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV 503 + VL S + ++A++ + + ++ + L +L +YMIP Sbjct: 496 SISQIAVLVREDIPGDTCTERSRSKRLVAYLVLKQDHVLTVSYLRQFLKETLPEYMIPAA 555 Query: 504 -IEIETVPVLVNGKV 545 + +E +P+ NGKV Sbjct: 556 FVFLEALPLTSNGKV 570 >UniRef50_Q2SHZ4 Cluster: Non-ribosomal peptide synthetase modules and related protein; n=1; Hahella chejuensis KCTC 2396|Rep: Non-ribosomal peptide synthetase modules and related protein - Hahella chejuensis (strain KCTC 2396) Length = 2624 Score = 104 bits (250), Expect = 1e-21 Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 10/181 (5%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHNTHP 200 IG PISN ++++DEN++ V G GE+ + G LARGY+ GK RFI NP + Sbjct: 785 IGRPISNTLIHIIDENLQLVPRGVAGELLIGGRGLARGYL-GKPELTAQRFIANPFSGDL 843 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTI-----PCVDNC 362 + +LYRTGD + + Y GR D QVK+RG R++L E++ ++ + V +C Sbjct: 844 S-ERLYRTGDLVRVNSDDQLEYLGRIDQQVKVRGFRIELGEIESCINGLRDNGKKLVKDC 902 Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNG 539 VV +S P + A+V + A +++ L L YMIP+ +I ++ +P+ NG Sbjct: 903 VVSVIKDDSLGPYLAAYVVSALGRSIDADDLKRRLARRLPGYMIPEAIIALDAIPLTANG 962 Query: 540 K 542 K Sbjct: 963 K 963 Score = 85.8 bits (203), Expect = 6e-16 Identities = 58/178 (32%), Positives = 93/178 (52%), Gaps = 6/178 (3%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP-HNTHP 200 IG P+ +++ ++ + G PGE+ + G LA+GYV D RFI ++H Sbjct: 1877 IGAPLCGVQLHIFNQLGQPAPAGAPGELYIGGVCLAQGYVGRDDLTSERFITTTIMSSHG 1936 Query: 201 NFA-KLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + +LYRTGD +G LY GR D QVKIRG RV+ EV+ +++ V V+ Sbjct: 1937 EISQRLYRTGDLARRTAQGEFLYLGRIDEQVKIRGFRVEPGEVEAVLNSHDDVKAAAVVA 1996 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + +LA++ A ++ A L L DYM P +++ +E +PV V+GK+ Sbjct: 1997 RD-DGAGMRLLAYIEPRHSAGFDVADLRAWLRKRLPDYMAPARILTLEKMPVTVSGKI 2053 >UniRef50_Q0PH95 Cluster: MassB; n=2; Pseudomonas fluorescens|Rep: MassB - Pseudomonas fluorescens Length = 4315 Score = 104 bits (250), Expect = 1e-21 Identities = 59/179 (32%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VP+G PISN +Y+LD ++ V G GE+C+ G +A+GY+ +F++NP Sbjct: 1919 SVPVGRPISNTQIYVLDAQLQPVPLGITGEICIGGEGVAKGYLNRAQLTAEKFVNNPFVD 1978 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A +YRTGD G ++G++ GR D QVKIRG R++L E++ +++ + VL Sbjct: 1979 QPG-ALMYRTGDLGRWSEEGLLECLGRNDDQVKIRGFRIELGEIEARLASCAGIQEVAVL 2037 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ T A + + A L L DYM+P + + ++P+ NGK+ Sbjct: 2038 AREDVPGDKRLVAYFTW-AGADLGIDQVHAHLQGQLPDYMLPSAYMPLASLPLTNNGKL 2095 Score = 95.1 bits (226), Expect = 9e-19 Identities = 58/183 (31%), Positives = 101/183 (55%), Gaps = 4/183 (2%) Frame = +3 Query: 9 HIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHN 182 H+ PIGV I + +Y+LD + G GE+ V G +ARGY+ + + RF+ + Sbjct: 862 HLVGMSPIGVRIPDLQLYVLDARREPLPLGVVGELYVGGAGVARGYLNREALNAERFVAD 921 Query: 183 PHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359 P ++Y+TGD G +L G + Y GR D QVK+RG R++L E+ ++T V + Sbjct: 922 PATG----LRMYKTGDLGRLLADGSVEYLGRNDDQVKVRGFRIELGEIQAHLATANGVRD 977 Query: 360 CVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536 VV+ + + ++A+V + E ++A + L SL ++M+P + ++T+P+ N Sbjct: 978 AVVIAREDQPGDKRLVAYVISDGELNVAA--LRDHLLRSLAEHMVPSAFVRLDTLPLTTN 1035 Query: 537 GKV 545 GK+ Sbjct: 1036 GKL 1038 Score = 94.3 bits (224), Expect = 2e-18 Identities = 60/177 (33%), Positives = 97/177 (54%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI+N +Y+LD ++ V G GE+ +AG +ARGY+ + RF+ +P Sbjct: 4054 PIGKPIANTRLYVLDGQLQPVPLGVAGELFIAGVQVARGYLNRPELTAERFLDDPFTP-- 4111 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD G L G + Y GR D QVKIRG R++L E+ + P V + VV+ Sbjct: 4112 --GRMYRTGDLGRYLPDGTLEYLGRNDDQVKIRGLRIELGEIQARLIEHPAVKDAVVV-- 4167 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+ T P ++ A+L L D+M+P + + ++ P+ NGK+ Sbjct: 4168 ---ARDQRLVAYYTGAP---ADIDSLRAQLLQHLPDFMVPALFMHLDAWPLSPNGKL 4218 Score = 85.8 bits (203), Expect = 6e-16 Identities = 57/176 (32%), Positives = 95/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI+N Y+LD ++R V G GE+ V G +ARGY+ + RF+ +P N Sbjct: 2990 IGRPIANATSYVLDAHLRPVPVGVAGELYVGGSGVARGYLNRPELTAERFLQDPFNA--- 3046 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++YRTGD L G + Y GR D QVK+RG RV+L E++ ++ + + VVL Sbjct: 3047 -GRMYRTGDLVRWLPDGNLEYLGRNDDQVKLRGVRVELGEIESRLAALDGIREAVVLV-- 3103 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +LA+ T + + + + A L + L + ++P ++++ +P+ NGK+ Sbjct: 3104 ---REGRLLAWFT--EQRPLQIETLRAHLQAQLPEALVPVAYMQLDQLPLTANGKL 3154 >UniRef50_Q0LP44 Cluster: Amino acid adenylation; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Amino acid adenylation - Herpetosiphon aurantiacus ATCC 23779 Length = 2596 Score = 104 bits (250), Expect = 1e-21 Identities = 65/180 (36%), Positives = 100/180 (55%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PI+N +Y+LD M+ V G GE+ + G NLARGY D RFI +P+ + Sbjct: 2292 SVPIGRPIANTQLYILDARMQPVPVGVAGELLIGGLNLARGYAERPDLTAERFIPHPYAS 2351 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A+LYRTGD D G I Y GR D Q+K+RG RV+L E++H +S P + V Sbjct: 2352 QAG-ARLYRTGDLARWRDDGAIEYLGRNDFQIKVRGIRVELGEIEHQLSQHPAIAQIV-- 2408 Query: 372 CYGVESSNPEILAFVTINPEARMSAKN-IEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 V +++A+ P+ + + + + L + L + MIP +++ +P+ NGK+ Sbjct: 2409 ---VHHHAGQLVAYWVARPDQAVPEETALRSWLRARLPEAMIPAHWLQLAELPLSSNGKL 2465 Score = 72.1 bits (169), Expect = 8e-12 Identities = 55/187 (29%), Positives = 90/187 (48%), Gaps = 15/187 (8%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH-- 197 IG PI + + +LD R G GE+ V G +A+GY+ + RFI +T Sbjct: 775 IGCPIPDLALAVLDAQGRQAGVGVAGELYVGGAGVAQGYLERPELNAQRFIQADASTPDL 834 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+ ++ YR+GD G + Y GR D QVKIRG R++L E++ A+S V + V+ Sbjct: 835 PSNSRWYRSGDLVRYWPNGELEYLGRIDLQVKIRGFRIELGEIEAALSQHAAVQSAAVIV 894 Query: 375 YGVESSNPEILAFVTINPEAR---------MSAKNIEAELTSSLTDYMIPQ-VIEIETVP 524 + ++ ++ + R + I +L L +YM P +IE+ + P Sbjct: 895 REDRPGHKRLVGYLIAKTQMRSVGAQTDPSLDLAAINQQLRERLPEYMWPSALIELASFP 954 Query: 525 VLVNGKV 545 + NGK+ Sbjct: 955 LTSNGKL 961 >UniRef50_A6YEH8 Cluster: CmnG; n=1; Saccharothrix mutabilis subsp. capreolus|Rep: CmnG - Streptomyces capreolus Length = 952 Score = 104 bits (250), Expect = 1e-21 Identities = 65/179 (36%), Positives = 96/179 (53%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 VPIGVP+ N +Y LD++ R G GE+ +AG LARGY + + H Sbjct: 325 VPIGVPLPNYRLYALDDDGRLCPPGITGEIHIAGAGLARGYRSAEATAKAFHELEVHSGR 384 Query: 204 FAKLYRTGDFGIL----DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LYRTGD L D+ + + GR DSQVKI G+RV+L+EVD AV +P V + V+ Sbjct: 385 TERLYRTGDLARLVRHADRWALEFQGRVDSQVKISGYRVELEEVDAAVKAVPGVRDAAVV 444 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 G E + + +V P R+ ++ LT L Y++P ++ +E +P NGK+ Sbjct: 445 VRG-EPAEQLVCCYVGDVPPDRLRSR-----LTERLPAYLVPHLLVPVEALPFTRNGKM 497 >UniRef50_A4FCX9 Cluster: Non-ribosomal peptide synthetase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Non-ribosomal peptide synthetase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 1048 Score = 104 bits (250), Expect = 1e-21 Identities = 60/177 (33%), Positives = 97/177 (54%), Gaps = 3/177 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGKDPHRFIHNPHNTHP 200 V IG PI N Y++++ R V G PGE+C+AG +A GY+ R ++ R + Sbjct: 747 VRIGEPIENTRFYVVNQRGRLVPPGVPGELCIAGDGVANGYLNRPEETERRFVDLAAAKG 806 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD + G +++ GR D Q+K+RGHRV+ E++H + P + VV Sbjct: 807 FSERVYRTGDLVRQIADGSLVFLGRTDHQLKVRGHRVEAAEIEHVLRRHPSISEAVVTL- 865 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 ++N ++A V + P+ +S++ + L SL YM+PQ + E P+ NGKV Sbjct: 866 ---AANATLVAHVEVIPDGSVSSEELRDLLAPSLPGYMVPQRFVVHEEFPLTPNGKV 919 >UniRef50_A3IP47 Cluster: Peptide synthetase; n=2; Cyanobacteria|Rep: Peptide synthetase - Cyanothece sp. CCY 0110 Length = 2942 Score = 104 bits (250), Expect = 1e-21 Identities = 65/177 (36%), Positives = 94/177 (53%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI N +YLLD N+ V G GE+ + G LARGY+ + +FI NP + Sbjct: 851 IGHPIDNTQMYLLDSNLEPVPIGVAGELYIGGDGLARGYLNRPELTAEKFIPNPFDPTGK 910 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LY+TGD L G I Y GR D QVKIRG R++L E++ +++ P V VV+ Sbjct: 911 -TRLYKTGDLCRYLPDGNIEYIGRIDHQVKIRGFRIELGEIESLLTSHPEVQESVVIARE 969 Query: 381 VESSNPEILAFVTINPEARMSA-KNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + N ++A++ S + + L L DYMIP + IE +P+ NGK+ Sbjct: 970 DQPGNKRLVAYIVTQEVGEDSLNQTLRDYLKGQLPDYMIPSAFVFIEKLPLTPNGKI 1026 Score = 94.3 bits (224), Expect = 2e-18 Identities = 61/188 (32%), Positives = 102/188 (54%), Gaps = 14/188 (7%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P++N +Y+L++ ++ V G GE+ + G + +GY+ +FI++P + Sbjct: 2377 VPIGRPVANTQLYILNQALKPVPVGAVGELHIGGVQVGKGYLNRPQLTAEKFINDPFSQD 2436 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A+LY+TGD L G I Y GR D QVKIRG R++L E++ ++ P V VV+ Sbjct: 2437 AE-ARLYKTGDLCRYLPDGNIEYLGRIDHQVKIRGFRIELGEIEGVLTQHPDVREVVVIV 2495 Query: 375 YGVESSNPEILAFVT--INPEARMSAKNIEAELTSS--------LTDYMIP-QVIEIETV 521 N +++A+V + P+ IE +L+ + L DYMIP + + ++ Sbjct: 2496 RQDHFDNKQLVAYVVSPLFPDDDEQVMTIEGKLSQALRDYLKDKLPDYMIPFAFVLLPSL 2555 Query: 522 PVLVNGKV 545 P+ NGK+ Sbjct: 2556 PLTPNGKI 2563 >UniRef50_UPI000045BE69 Cluster: COG1020: Non-ribosomal peptide synthetase modules and related proteins; n=1; Nostoc punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide synthetase modules and related proteins - Nostoc punctiforme PCC 73102 Length = 1401 Score = 104 bits (249), Expect = 2e-21 Identities = 56/179 (31%), Positives = 101/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 ++P G P+SN +++LDE ++ + PG++ + G LA+GY R K FI +P Sbjct: 857 SIPYGKPLSNQSIHILDEALQPRPDWVPGQIYIGGVGLAQGYWRDAAKTQASFIQHPRTG 916 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LY TGD G L G I + GR D QVKIRG+R+++ E++ + P + + V Sbjct: 917 E----RLYCTGDLGRYLPDGNIEFLGRIDFQVKIRGYRIEIGEIETVLQQHPAIRSVAVS 972 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 G + + +++A++ E +++ + + L L +YMIP + + ++++P+ NGKV Sbjct: 973 AVGEQRDDKQLVAYIVFEQEQSITSLELRSYLQQKLPEYMIPSMFMFMDSLPLSSNGKV 1031 >UniRef50_Q0SE34 Cluster: Non-ribosomal peptide synthetase; n=1; Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide synthetase - Rhodococcus sp. (strain RHA1) Length = 4903 Score = 104 bits (249), Expect = 2e-21 Identities = 65/179 (36%), Positives = 95/179 (53%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 TVPIGVP + V +LD + V G PGE+ +AG LARGY+ G RF NP Sbjct: 4372 TVPIGVPQNGVGVLVLDSRLHPVPIGVPGELYLAGAQLARGYLGQPGATAARFPANPWG- 4430 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD + G I Y GR D QVKIRG RV+L+E++ A+ V Sbjct: 4431 -PPGQRMYRTGDVVSRRRDGTIDYLGRRDLQVKIRGQRVELEEIETALRRHAAVAQSAAA 4489 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 Y + ++ +V +P+ + + + AEL L YM+P Q++ + +P +GK+ Sbjct: 4490 VYESAGTGARLVGYVVPHPDMVVDTRAVSAELAQRLPRYMVPNQIVVLGALPSTPHGKL 4548 Score = 92.7 bits (220), Expect = 5e-18 Identities = 59/179 (32%), Positives = 92/179 (51%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +V IG PI N Y+LD +R V G GE+ +AG LARGY D RF+ +P Sbjct: 2273 SVAIGRPIHNIRTYVLDSRLRPVPVGTRGELYLAGAYLARGYAGRPDLTAERFVADPFGE 2332 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 ++YRTGD ++ G + Y GR D Q+K+RG RV+ E++ A+++ P V + V Sbjct: 2333 --TGGRMYRTGDVVRWNESGRLEYLGRTDFQIKLRGQRVEPGEIESALTSDPAVTHAAVT 2390 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + ++A+V + I L L YMIP V+ + +P+ +GK+ Sbjct: 2391 VHRDAEAGDRLIAYVVAADGVPPDERRIVDRLAGLLPAYMIPSAVVPLPALPLTTSGKL 2449 Score = 72.9 bits (171), Expect = 4e-12 Identities = 53/178 (29%), Positives = 86/178 (48%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V IG PI V LLD + V G GE+ ++G +ARGY R RF+ +P Sbjct: 3316 VTIGRPIRGAAVLLLDSRLHPVPTGVAGELYISGPGVARGYHRRPALTAARFVASPFGA- 3374 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + ++YRTGD G + G I Y R DSQ+++RG R++L E+D + P V Sbjct: 3375 -SGERMYRTGDVGRWRRDGSIEYLHRNDSQIELRGVRIELGEIDATLLAHPTVRFAATDV 3433 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++++V + + + L ++P V+ ++ VP+ VNGK+ Sbjct: 3434 RELRDGVDALVSYVVPARNETVDPDQLIRFAATRLPMPLVPAIVVVVDAVPLTVNGKL 3491 Score = 71.7 bits (168), Expect = 1e-11 Identities = 52/178 (29%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNTH 197 V +G PI +LD +R V G GE+ VAG LARGY R + RF+ +P+ Sbjct: 764 VTVGRPIRGARAVVLDHRLRPVPVGVVGELYVAGTALARGYHRNARQTSERFVADPYG-- 821 Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD + Y GR+D QV +RG RV+ E+D + P V V + Sbjct: 822 PPGTRMYRTGDTVRWTYDHELEYLGRSDEQVNLRGLRVEPGEIDATLLRYPAVRFAVTVI 881 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + +++++V + + ++ +++ + L++ L +++P V+ + +P+ +GK+ Sbjct: 882 RS-RGAGDQLVSYV-VGADT-VTEQDLLSFLSTELPPHLVPAAVVVLPDIPLTPSGKL 936 >UniRef50_A4F3K7 Cluster: Non-ribosomal peptide synthetase; n=3; root|Rep: Non-ribosomal peptide synthetase - Planktothrix agardhii NIVA-CYA 126 Length = 1622 Score = 104 bits (249), Expect = 2e-21 Identities = 63/177 (35%), Positives = 95/177 (53%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG P N VYLLD N + V G GE+ V+G LARGY + +FI NP + Sbjct: 788 PIGKPAVNVKVYLLDSNFQPVPLGSIGELYVSGAGLARGYFNRPELTTEKFIPNPFD-QD 846 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++++LY+TGD L G I + GR D +VKIRG+ V+L E++ ++ P + VV Y Sbjct: 847 SYSRLYKTGDLARYLSDGNIEFLGRIDDRVKIRGYSVELGELEAVLNKHPFLSQAVVKVY 906 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 G + + A+ ++ + + L L +YMIP + +E+ P+ NGKV Sbjct: 907 GESAREKYLCAYFVPLQSQTITIEQLRHFLQEQLPEYMIPSAFVPMESFPLTSNGKV 963 >UniRef50_Q2SFM4 Cluster: Non-ribosomal peptide synthetase modules and related protein; n=2; cellular organisms|Rep: Non-ribosomal peptide synthetase modules and related protein - Hahella chejuensis (strain KCTC 2396) Length = 2853 Score = 103 bits (248), Expect = 2e-21 Identities = 65/180 (36%), Positives = 98/180 (54%), Gaps = 8/180 (4%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 +G PI+N +Y+LD+ +R +G GE+ VAG LARGY+ G RF+ +P Sbjct: 775 VGRPIANTRIYVLDQALRYAPQGVTGELYVAGAGLARGYLTRPGMTAARFVADPEGQGD- 833 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +YRTGD G + + GR+D QVK+RG RV+L EV+HA+ +P V VV Sbjct: 834 --LMYRTGDLVRWTPDGQLEFVGRSDRQVKVRGFRVELGEVEHALEALPGVSGAVVTAAT 891 Query: 381 VESSNPEILAFVTINPEARMSAK----NIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 +S+ + A+ T+N R + + +L+ L DYM+P + I P+ VNGK+ Sbjct: 892 AGASH-RLTAYCTVNEGLRHDDEALRDRLYRQLSEMLPDYMMPSALAILPAWPLTVNGKI 950 Score = 85.4 bits (202), Expect = 8e-16 Identities = 57/188 (30%), Positives = 98/188 (52%), Gaps = 12/188 (6%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 L+VPIG P+ N + +LD+ +R G GE+ + G LA GY+ D RF+ + Sbjct: 2316 LSVPIGRPVWNTQLRILDQWLRPAPVGVAGELYLCGAQLADGYLGRPDLTAARFVAD--- 2372 Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 T A++YRTGD L G + Y GR+D Q+KIRG R++L +++ A+ +P V VV Sbjct: 2373 TEGEGARMYRTGDVARWLSNGDVEYLGRSDDQLKIRGQRIELGDIESALQNLPDVKRAVV 2432 Query: 369 LCYGVE--------SSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETV 521 + + N +++ +V + + + A + L +L +M+P ++ + Sbjct: 2433 CARVINNGEAAMAGADNRQLVGYVIPHAD-DIDADALRRRLAETLPAHMVPVAIVPVREF 2491 Query: 522 PVLVNGKV 545 P+ NGK+ Sbjct: 2492 PLSANGKL 2499 >UniRef50_Q6E7J8 Cluster: JamL; n=4; Bacteria|Rep: JamL - Lyngbya majuscula Length = 3935 Score = 103 bits (248), Expect = 2e-21 Identities = 62/186 (33%), Positives = 103/186 (55%), Gaps = 11/186 (5%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP--- 185 TVPIG PISN +Y+LD+ + G PGE+ V G +A+GY+ + +FI NP Sbjct: 3617 TVPIGKPISNTQIYILDKYGNLLPPGIPGELYVGGDGIAQGYLSHPELTQEKFILNPFTK 3676 Query: 186 ----HNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPC 350 NT N +LY+TGD L G I + GR D+Q+K+RG R++L E++ ++ Sbjct: 3677 DKKSQNTEAN--RLYKTGDLARWLPDGNIEFVGRIDNQIKLRGFRIELGEIEALLNGHSQ 3734 Query: 351 VDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPV 527 + VV+ N ++A++ + E+ +S K + L +YMIP + ++++P+ Sbjct: 3735 IQQAVVIAREDIPGNKRLVAYIVASDES-LSTKELREFTKQKLPEYMIPSAFVTLDSLPL 3793 Query: 528 LVNGKV 545 + NGK+ Sbjct: 3794 MPNGKI 3799 >UniRef50_Q5MP00 Cluster: OnnI; n=1; symbiont bacterium of Theonella swinhoei|Rep: OnnI - symbiont bacterium of Theonella swinhoei Length = 5052 Score = 103 bits (248), Expect = 2e-21 Identities = 63/182 (34%), Positives = 95/182 (52%), Gaps = 8/182 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 + IG PI N +Y+LD N V G PGE+C+ G LARGY+ + +F+ +P + Sbjct: 1617 IVIGKPIQNTGIYILDHNRALVPIGVPGELCIDGDGLARGYLHKPELTAEKFMDHPFH-- 1674 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV-- 368 K+Y TGD L G I Y GR D QVKIRG R++L E++ + +P + + VV Sbjct: 1675 -RGKKIYHTGDLARWLPNGTIEYLGRLDLQVKIRGFRIELGEIEFQLKQLPGIRDAVVVA 1733 Query: 369 --LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNG 539 + +E + + F+ + + + A L L DYM+P I +E +P+ NG Sbjct: 1734 KDMAKDMEGLHQLVAYFIPGGGPESVDTEVLRAGLKQKLADYMVPAFFIPLEEIPLTPNG 1793 Query: 540 KV 545 KV Sbjct: 1794 KV 1795 >UniRef50_Q3WDU5 Cluster: Amino acid adenylation; n=1; Frankia sp. EAN1pec|Rep: Amino acid adenylation - Frankia sp. EAN1pec Length = 2547 Score = 103 bits (248), Expect = 2e-21 Identities = 61/176 (34%), Positives = 98/176 (55%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 +G PI V++LD+++R V G GE+ V+G LARGY+ G RF+ +P P Sbjct: 1805 VGGPIPGLRVHVLDQHLRPVAPGGLGELYVSGGQLARGYLGRPGLTATRFVADPFGG-PG 1863 Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD G Y GRAD QVK+RG R++L E+ A++T P V+ VVL Sbjct: 1864 -ARMYRTGDLARRTADGGFEYLGRADDQVKVRGFRIELGEIQAAIATHPAVEQAVVLARE 1922 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++ +V P R+ ++ + + L ++M+P V+ ++ P+ NGK+ Sbjct: 1923 DQPGQRRLVGYVVAAPGRRVDSEELRRHAAAMLPEFMVPVAVLALDAFPLTGNGKL 1978 Score = 87.4 bits (207), Expect = 2e-16 Identities = 55/177 (31%), Positives = 89/177 (50%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 +G PI + VYLLD + V G PGE+ + G +A GY+R G RF+ +P + Sbjct: 668 VGRPIRSTQVYLLDTALAPVAPGMPGELYIGGAGVADGYLRRPGLTASRFVADPFSAG-- 725 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LYRTGD G + GR D QVK+RG R++ EV+ + P V C V+ Sbjct: 726 -GRLYRTGDLARWTADGELDVLGRVDDQVKVRGFRIEPGEVEAVLGRHPAVARCAVVARD 784 Query: 381 VESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A+V P + + L ++L ++M+P +++ +P NGK+ Sbjct: 785 DGPAGRHLVAYVVPAAPGTVVDPALLREHLAAALPEHMVPGAFVQLAALPTTPNGKL 841 >UniRef50_Q1D6B8 Cluster: Non-ribosomal peptide synthetase; n=5; Bacteria|Rep: Non-ribosomal peptide synthetase - Myxococcus xanthus (strain DK 1622) Length = 4567 Score = 103 bits (248), Expect = 2e-21 Identities = 62/176 (35%), Positives = 97/176 (55%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 +G P++N Y+LD ++ V G PGE+ + G LARGY+ + RFI NP +T Sbjct: 4019 LGGPLANAQTYVLDAYLQPVPVGVPGELYIGGAGLARGYLNRPELTADRFIPNPFSTASG 4078 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LYRTGD L +G + + GR D QVK+RG R++L E++ A+ P V + VVL Sbjct: 4079 -ARLYRTGDRARWLPQGELEFLGRIDFQVKLRGFRIELGEIESALRQHPAVRDTVVLVRE 4137 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+V P A + + L L ++M+P + +E +P+ +GKV Sbjct: 4138 DTPGLQRLVAYVVAEPAATVDSGTFRPFLKERLPEHMMPSAFVTLEALPLNTSGKV 4193 Score = 100 bits (240), Expect = 2e-20 Identities = 60/180 (33%), Positives = 99/180 (55%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG P+ ++ Y+LD M V G PGE+ V G LA GY+ + +F+ +P ++ Sbjct: 2951 SVPIGRPLGHSTAYVLDSRMEPVPVGVPGELFVGGDGLAWGYLSRPELTAEKFLPHPFSS 3010 Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LYRTGD G + + GR+D QVK+RG R++L E++ + P V VVL Sbjct: 3011 APG-ARLYRTGDRVRWRADGSLEFLGRSDFQVKVRGFRIELGEIESVLQQAPGVQEAVVL 3069 Query: 372 CYGVESSNPEILAFVTINPEAR-MSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V + A+ + + L +Y++P + I +E++P+ NGKV Sbjct: 3070 AREDSPGDKRLVAYVVGEDGVESVDARALRDHVLRKLPEYLVPAIFIPMESLPLSANGKV 3129 Score = 99 bits (238), Expect = 3e-20 Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 6/178 (3%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 +G P++N Y+LD ++ V G PGE+ + G LARGY+ + RFI NP +T Sbjct: 1891 LGGPLANAQTYVLDAYLQPVPVGVPGELYIGGAGLARGYLNRPELTADRFIPNPFSTASG 1950 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+LYRTGD L +G + + GR D QVK+RG R++L E++ A+ P V + VVL Sbjct: 1951 -ARLYRTGDRARWLPQGELEFLGRIDFQVKVRGFRIELGEIESALRQHPAVRDTVVLVRE 2009 Query: 381 VESSNPEILAFVTINPEAR--MSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+V EA + + L L ++M+P + +E +P+ NGK+ Sbjct: 2010 DTPGLQRLVAYVVAEAEATTVVDSGTFRPFLKERLPEHMVPSAFVTLEALPLTPNGKL 2067 Score = 97.5 bits (232), Expect = 2e-19 Identities = 63/185 (34%), Positives = 98/185 (52%), Gaps = 10/185 (5%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG P+ ++ Y+LD M V G PGE+ V G LA GY+ + +F+ +P ++ Sbjct: 820 SVPIGRPLGHSTAYVLDSRMEPVPVGVPGELFVGGDGLAWGYLSRPELTAEKFLPHPFSS 879 Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LYRTGD G + + GR+D QVK+RG R++L E++ + P V VVL Sbjct: 880 APG-ARLYRTGDRVRWRADGSLEFLGRSDFQVKVRGFRIELGEIESVLQQAPGVQEAVVL 938 Query: 372 CYGVESSNPEILAFVTINPEARMSAK------NIEAELTSSLTDYMIPQV-IEIETVPVL 530 + ++A+ AR + I L + L +YM+P V + +E +P+ Sbjct: 939 AREDAPGDKRLVAYFVPTAAARSEEQAANAVGGIRTFLKARLPEYMLPAVFMPLEVLPLS 998 Query: 531 VNGKV 545 NGKV Sbjct: 999 PNGKV 1003 >UniRef50_Q1D3K9 Cluster: Non-ribosomal peptide synthase; n=1; Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide synthase - Myxococcus xanthus (strain DK 1622) Length = 2048 Score = 103 bits (248), Expect = 2e-21 Identities = 60/179 (33%), Positives = 101/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +V IG PI+N +Y+LDE++R V G GE+ + G +ARGY+ + RF+ +P Sbjct: 845 SVAIGRPIANTRLYVLDEHLRLVPVGVHGELYIGGDGVARGYLDRPELTAERFVPDPFGD 904 Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LYRTGD GV+ + GR D QVK+RG+R++L E++ + P V VV+ Sbjct: 905 VPG-ARLYRTGDRVRRFPDGVLDFLGRRDEQVKVRGYRIELGEIEGVLGQAPGVREVVVV 963 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+V N A + + + + L ++++P V+ ++ +P+ NGKV Sbjct: 964 AREDIEGSKRLVAYVVPNEGADVEPEVLRQLARAKLPEHLVPSVVVPLDALPLSPNGKV 1022 >UniRef50_O87314 Cluster: FxbC; n=5; Mycobacterium smegmatis|Rep: FxbC - Mycobacterium smegmatis Length = 4976 Score = 103 bits (248), Expect = 2e-21 Identities = 61/176 (34%), Positives = 101/176 (57%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG P+ ++LLD N++ V G GE+ +AG +ARGY G RF+ NP + Sbjct: 1887 IGGPLPGLRIHLLDNNLQPVPAGVVGEMYIAGGQVARGYTGRPGLTATRFVANPFDGAGE 1946 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LYR+GD + D G ++Y GR+D+QVK+RG+R++L EV+ A+ T+P V N Sbjct: 1947 --RLYRSGDLAMWTDAGELVYLGRSDAQVKVRGYRIELGEVEAALVTLPGVTNAAADVRH 2004 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ ++ +V + + A + + L L DYM+P V + ++ +P+ VNGK+ Sbjct: 2005 DDTGRARLIGYV-VGDALDIGA--LRSTLAERLPDYMVPSVLLRLDVLPLTVNGKL 2057 Score = 95.5 bits (227), Expect = 7e-19 Identities = 60/179 (33%), Positives = 95/179 (53%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 T +G PI N ++LD +R V +G PGE+ +AG LARGY+ G RF+ NP Sbjct: 3412 TPTVGTPIWNTRAHILDNWLRPVPDGVPGELYIAGAGLARGYLGQPGLTASRFVANPFEP 3471 Query: 195 HPNFAKLYRTGDFGILDKGV-ILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 ++YRTGD + I + GR D QVKIRG+RV+L +++ A+ + P V+ Sbjct: 3472 ----GRMYRTGDLVVRRADDNIDFLGRTDDQVKIRGYRVELGDIEAALVSTPASHRPRVI 3527 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIET-VPVLVNGKV 545 + + ++A+V E ++ LT++L YM+P + T +P+ NGK+ Sbjct: 3528 ARPDTAGSSRLVAYVVPTTENPDVLDDLRMHLTATLPAYMVPTAMATLTEIPLTDNGKL 3586 Score = 80.6 bits (190), Expect = 2e-14 Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 11/186 (5%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 T +G PI N Y+LD +R V +G GE+ +AG LA GY R G + +P+ Sbjct: 379 TPTVGQPIWNTRGYILDAALRPVPDGAVGELYIAGTGLALGYHRRAGLTAATMVADPYV- 437 Query: 195 HPNFAKLYRTGDFGILDKG---VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 P ++YRTGD G ++ Y GR D QVKIRG+RV+L E++ ++ V C Sbjct: 438 -PG-GRMYRTGDLVRRRPGSAELLDYLGRVDDQVKIRGYRVELGEIESVLTRADGVARCA 495 Query: 366 VLCYGVESSNP--EILAFVTIN---PEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPV 527 V+ ++ P + A+V + E + L L YM+P I +T+P+ Sbjct: 496 VVARATGANPPVKTLAAYVIPDRWPAEDAAFITGLRDHLARVLPGYMVPTRYGIVDTLPL 555 Query: 528 LVNGKV 545 +NGK+ Sbjct: 556 TINGKL 561 Score = 74.9 bits (176), Expect = 1e-12 Identities = 54/178 (30%), Positives = 90/178 (50%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGK-DPHRFIHNPHNTH 197 V +GVP N Y+LD+ + V G PGE+ +AG LA GY+ RG RF+ +P + Sbjct: 4443 VALGVPGWNVRAYVLDDYLNPVPAGAPGELYLAGIQLADGYLHRGALTAARFVASPFD-- 4500 Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A++YRTGD G + Y GR+D Q+K+RG R++ E++ ++T P V + V+ Sbjct: 4501 -QGARMYRTGDVVRWRADGQLEYLGRSDDQIKLRGVRIEPGEIETVLATHPAVSSVRVIA 4559 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 G + A + A + ++L +M+P + + P+ +GK+ Sbjct: 4560 RGGRLMAYYVPA--GVEASAGELRDELREHAAAALPSHMVPSGFVALTEFPLTPSGKL 4615 >UniRef50_A3HT12 Cluster: Non-ribosomal peptide synthase; n=1; Algoriphagus sp. PR1|Rep: Non-ribosomal peptide synthase - Algoriphagus sp. PR1 Length = 1396 Score = 103 bits (248), Expect = 2e-21 Identities = 61/180 (33%), Positives = 98/180 (54%), Gaps = 3/180 (1%) Frame = +3 Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGKDPHRFIHNPHN 191 F VPIG+ SN Y+LDE G GE+C+AG L +GY+ + + +F+ NP++ Sbjct: 799 FHKVPIGLATSNALAYVLDEQQELSPVGISGELCIAGAGLTKGYLSKSETDEKFLKNPYS 858 Query: 192 THPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 + ++Y+TGD + K G+I Y GR D+QVKIRGHR++L E+ P V V Sbjct: 859 --EVWDRIYKTGDLVRIQKDGLIEYLGRKDNQVKIRGHRIELAEIQELALQFPQVQMAVA 916 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 L +P+++ T ++ + + L L +M+P ++++E P+L NGKV Sbjct: 917 LV--SNEKDPQLMLAYTSG--QKLEEGELISFLREKLPRFMVPDLLLQLEEFPLLPNGKV 972 >UniRef50_A0ZL89 Cluster: Non-ribosomal peptide synthase; n=1; Nodularia spumigena CCY 9414|Rep: Non-ribosomal peptide synthase - Nodularia spumigena CCY 9414 Length = 1490 Score = 103 bits (248), Expect = 2e-21 Identities = 64/179 (35%), Positives = 102/179 (56%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGKDPH-RFIHNPHNT 194 +V IG PI+N +Y+LD+N++ V G GE+ + G LARGY+ R + H +FI N T Sbjct: 819 SVSIGSPIANTEIYILDQNLQPVPIGVFGELHIGGAGLARGYLNRPELTHEKFISNLIPT 878 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + ++LY+TGD L G I + GR D QVKIRG R++L E++ ++ P V V+ Sbjct: 879 AKS-SRLYKTGDLARYLPDGNIEFLGRIDYQVKIRGFRIELGEIEAVLAQHPLVKTSAVI 937 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++ + +I+A+V +A + N + L L DYMIP + + +P+ GK+ Sbjct: 938 VREIQLGSKQIVAYVVTQEDADIQT-NFRSFLQEKLPDYMIPAFFVRLAELPLTTTGKI 995 >UniRef50_Q8CJX2 Cluster: CDA peptide synthetase III; n=3; Streptomyces|Rep: CDA peptide synthetase III - Streptomyces coelicolor Length = 2417 Score = 103 bits (247), Expect = 3e-21 Identities = 65/178 (36%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P VY+LD +R V G GEV +AG LARGY+ G RF +P Sbjct: 783 VPIGTPHEGVRVYVLDSALRPVAPGLDGEVYLAGVQLARGYLGRGGLTAERFTADPFGA- 841 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +++YRTGD ++ G +++AGRAD QVK+RG+R++L E++ AV+ P V V+ Sbjct: 842 PG-SRMYRTGDVAHWNEAGELVFAGRADRQVKLRGYRIELGEIEAAVAGGPGVRQAAVVL 900 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V +P A L SL D+M+P + ++ +P+ NGK+ Sbjct: 901 REDRPGDQRLVAYVVPDP-GHWDEAAARARLALSLPDFMMPSAFVALDALPLSPNGKL 957 Score = 89.8 bits (213), Expect = 4e-17 Identities = 58/177 (32%), Positives = 92/177 (51%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI++ Y+LD+ ++ V G PGE+ V G LARGY+ RF+ P P Sbjct: 1846 PIGRPIADTAGYVLDDALQPVPPGVPGELYVRGPGLARGYLGRPSLTAGRFVACPFG--P 1903 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +YRTGD G + Y GR D+QVK+RG RV+ E++ + +P V VL Sbjct: 1904 AGGVMYRTGDLVRHRADGDLEYLGRTDTQVKLRGMRVEPAEIEAVTAGLPGVAQAAVLVR 1963 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++ +V + A + + L SL +YM+P ++ ++ +P+ NGK+ Sbjct: 1964 EDTPGDRRLVGYVVPDAGASVDPGALRQALRGSLPEYMVPAALVVLDALPLTTNGKL 2020 >UniRef50_Q7N3S1 Cluster: Complete genome; segment 9/17; n=1; Photorhabdus luminescens subsp. laumondii|Rep: Complete genome; segment 9/17 - Photorhabdus luminescens subsp. laumondii Length = 916 Score = 103 bits (247), Expect = 3e-21 Identities = 62/186 (33%), Positives = 106/186 (56%), Gaps = 11/186 (5%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG P+SN ++LD + + E E GE+ +AG +ARGY+ +D F+ Sbjct: 370 SVPIGKPVSNTEFFILDHHYQLASEYEIGEIYIAGTQVARGYLNRQDLTEKHFLEIAIPP 429 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + +LYRTGD DK G +AGR D+Q+K+RG RV+L+E+ +A+ I V + +L Sbjct: 430 NTQKIRLYRTGDLAYWDKEGNAHFAGRKDNQIKVRGMRVELEEIKNAIEVIDQVKHAAIL 489 Query: 372 C-YGVESSNPEILAFV-----TINPEARMSAKNI-EAELTSSLTDYMIP-QVIEIETVPV 527 + + + A + TI +A+ +I +EL+ +L DYM+P + + ++T+P+ Sbjct: 490 AEKDPQHRSTRLTACIELADETIRQQAKYDITSILRSELSKTLPDYMLPDRFLFLDTMPL 549 Query: 528 LVNGKV 545 +GK+ Sbjct: 550 TSSGKI 555 >UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4; Photorhabdus luminescens subsp. laumondii|Rep: Complete genome; segment 11/17 - Photorhabdus luminescens subsp. laumondii Length = 5457 Score = 103 bits (247), Expect = 3e-21 Identities = 63/176 (35%), Positives = 97/176 (55%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P+ N VYLLD + V G GE+ + G +ARGY + F+ +P + +PN Sbjct: 4904 IGRPLPNTRVYLLDVQGQPVPLGVEGELYIGGVGVARGYFNRAELTAEYFLTDPFSDNPN 4963 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD L G + + GR D QVKIRG RV+ E++ + P V VVL G Sbjct: 4964 -ARMYRTGDLVRYLPDGNLEFLGRNDHQVKIRGFRVEPGEIEARLVEHPAVSQSVVLALG 5022 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E + ++A+V + R+ A ++ L++ L DYM+P + ++ P+ NGK+ Sbjct: 5023 -EGQDKRLVAYVVAQADERL-ANSLRTHLSAILPDYMVPSAFVRLDAFPLTPNGKL 5076 Score = 101 bits (242), Expect = 1e-20 Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI+N +YLL+ + V G GE+ V G +A GY+ D RF+ +P + Sbjct: 1672 IPIGRPIANTRIYLLNAYGQPVPLGVTGEIYVGGDGVACGYLNRPDQTAERFLTDPFSDQ 1731 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+ A++YRTGD L G + + GR D QVKIRG R++ E++ + P V VL Sbjct: 1732 PD-ARMYRTGDLARYLPDGNLEFLGRNDQQVKIRGFRIEPGEIEARLVEHPAVREAAVLA 1790 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 G + S+ ++A+V + A + L++ L DYM+P + +E P+ NGK+ Sbjct: 1791 LG-DGSDKRLVAYVAAEAHEGL-AMTLRDHLSAILPDYMVPSAFVRLEAFPLTPNGKL 1846 Score = 99 bits (238), Expect = 3e-20 Identities = 65/177 (36%), Positives = 97/177 (54%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG PI N VYLLD N + V G GE+ + G +ARGY+ RFI + N P+ Sbjct: 2751 IGRPIRNTRVYLLDRNRQPVPLGCVGEMYIGGVGVARGYLNRLALSEERFIPDVFNPVPD 2810 Query: 204 FAKLYRTGDFG--ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A++YRTGD +LD G + + GR D QVKIRG RV+L E++ + P V VL Sbjct: 2811 -ARMYRTGDLARYLLD-GELEFLGRNDQQVKIRGFRVELGEIETRLVEYPAVQEAAVLAL 2868 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + ++A+V ++A+ + L++ L DYMIP + +++ P NGK+ Sbjct: 2869 D-DGQDKRLVAYVVAEANEGLAAR-LREYLSAVLPDYMIPVAFVRLDSFPQTPNGKL 2923 Score = 99.1 bits (236), Expect = 6e-20 Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI+N VYLLD + V G GE+ V G +A+GY+ + RF+ +P + Sbjct: 3824 IPIGRPIANTRVYLLDVYGQPVPPGVIGEIYVGGDGVAQGYLNRPELTAERFLVDPFSDD 3883 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+ A++YRTGD L G + + GR D QVKIRG R++ E++ + P V VL Sbjct: 3884 PD-ARMYRTGDLARYLPDGNLEFMGRNDQQVKIRGFRIEPGEIEARLVEHPAVREAAVLA 3942 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 G + + ++A+V + + ++ A L+ L DYM+P + ++ P+ NGK+ Sbjct: 3943 LG-DGPDKRLVAYVVALADDGL-VNSLRAYLSKILPDYMVPSAFVRLDAFPLTPNGKL 3998 Score = 80.6 bits (190), Expect = 2e-14 Identities = 54/176 (30%), Positives = 89/176 (50%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG P N +YLLD+ V G GE+ + G +ARGY+ RF+ + + Sbjct: 602 IGRPAKNARIYLLDKYGELVPAGCVGEMYIGGVGVARGYLNRPALSVERFMLDTFSPVSG 661 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++YR+GD L G + + GR D QVKIRG R++L E++ ++ P V VL Sbjct: 662 -ERMYRSGDLARYLPDGDLEFLGRNDEQVKIRGFRIELGEIETRLTEHPAVQEAAVLALD 720 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V + A ++ L++ L DYM+P + ++T P +GK+ Sbjct: 721 GDQGK-RLVAYVEAKANEGL-AVDLREYLSAILPDYMVPAAFVRLDTFPQTPSGKL 774 >UniRef50_Q20CI8 Cluster: CesB; n=7; cellular organisms|Rep: CesB - Bacillus cereus Length = 2681 Score = 103 bits (247), Expect = 3e-21 Identities = 62/179 (34%), Positives = 98/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++PIG PI+N+ Y+LD + G GE+CV G +A+GYV + RFI +P Sbjct: 2135 SIPIGTPIANSSAYILDVHQNIQPIGVVGELCVGGDGVAKGYVNLEQLTEERFIADP--- 2191 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + +YRTGD+ +L G I Y GR D+QVKIRG R++L+ + + + + + +V+ Sbjct: 2192 FLKGSTMYRTGDYVKLLPNGNIQYIGRVDNQVKIRGFRIELEAIMNTLKQCESIKDVIVV 2251 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 V+ N + E +S + + A L +YM+P Q I IE +P+ +NGKV Sbjct: 2252 ---VQEQNGYKTLVAYVVGEESLSIETVRAYAKKHLAEYMVPSQFIFIEEIPLSINGKV 2307 Score = 34.3 bits (75), Expect = 1.9 Identities = 21/87 (24%), Positives = 43/87 (49%) Frame = +3 Query: 285 VKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAE 464 V+I+G RVDL++++ V+ + ++ C V+ + + AFV + +A E + Sbjct: 13 VRIQGKRVDLKKIERQVAKVSFIEQCAVIARKQDDGEYLLTAFVV----SEKAAAKEELQ 68 Query: 465 LTSSLTDYMIPQVIEIETVPVLVNGKV 545 L L Q+I + ++P+ G + Sbjct: 69 LLEVLPPK--SQIISMSSLPLTKEGTI 93 >UniRef50_Q1IA18 Cluster: Putative non-ribosomal peptide synthetase; n=1; Pseudomonas entomophila L48|Rep: Putative non-ribosomal peptide synthetase - Pseudomonas entomophila (strain L48) Length = 2990 Score = 103 bits (247), Expect = 3e-21 Identities = 61/177 (34%), Positives = 98/177 (55%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200 PIG PI+N +Y+LD ++ G PGE+ +AG LARGY+ RF+ +P + P Sbjct: 1409 PIGKPIANARLYVLDGDLNPQPVGVPGELYIAGHCLARGYLNRAPLSAERFLPDPFSPAP 1468 Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A++YR+GD +L G + Y GR D QVK+RG R++L E+D + P V + VL Sbjct: 1469 G-ARMYRSGDLALLQADGNVQYLGRVDQQVKLRGFRIELGEIDSLLRQQPGVQDVAVLLR 1527 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + +P ++A+V A+ + A L L ++M+P + + +P+ NGK+ Sbjct: 1528 EDVAGDPRLVAYVV----GTGDAQTLRAALQRQLPEHMLPTAWVSLAQLPLTRNGKL 1580 Score = 89.0 bits (211), Expect = 6e-17 Identities = 58/179 (32%), Positives = 92/179 (51%), Gaps = 6/179 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPH----RFIHNPHN 191 +PIG P++N VYL D + E GEV + G +ARGY+ PH RF+ NP Sbjct: 353 LPIGRPLANCRVYLFDAQGQA---SEEGEVYLGGVGVARGYLNL--PHLTAERFVDNPFV 407 Query: 192 THPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 +LYRTGD L G + + GR D Q K+RG R++L E++ ++ +P V +V Sbjct: 408 AGE---RLYRTGDLARLRADGQLEFLGRNDHQAKLRGLRLELGEIEARLAEVPGVRESLV 464 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542 P ++A+ + A ++ + +L L DYM+P +++ +P+ NGK Sbjct: 465 QLRQDTPGEPRLVAYYARHEGAALTPAELSRQLRMHLPDYMVPSAFVQLPALPLTANGK 523 Score = 81.4 bits (192), Expect = 1e-14 Identities = 53/177 (29%), Positives = 90/177 (50%), Gaps = 2/177 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 ++P G + + ++LD+ ++ G + + G LA+GY R DP + + Sbjct: 2461 SIPYGQALDHQRFHVLDDALQVRPTWVTGHLYIGGIGLAKGYWR--DPALSARSFFDHPL 2518 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +LYRTGD G L G I + GR D+QVK++G+R++L E++ ++ P V + VV Sbjct: 2519 TGERLYRTGDLGRRLPDGNIEFLGRDDNQVKVQGYRIELGEIETVLNRHPGVHSAVVRIL 2578 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 G E+ + LA + + + A + + L L YM+P +E P+ NGKV Sbjct: 2579 G-EAQAQKRLAGYVLKADPALQAGDFNSYLADKLPAYMVPSSFTFVEAWPLSANGKV 2634 >UniRef50_Q0K0K4 Cluster: Non-ribosomal peptide synthetase; n=1; Ralstonia eutropha H16|Rep: Non-ribosomal peptide synthetase - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 2008 Score = 103 bits (247), Expect = 3e-21 Identities = 65/177 (36%), Positives = 99/177 (55%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHP 200 PIG P+ Y+LD + V G PGE+ + G LARGY+ G RFI +P P Sbjct: 825 PIGRPVGARSAYVLDSRLEPVPVGVPGELYLGGEGLARGYLGRAGMTADRFIPDPFGA-P 883 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +LYRTGD G I Y GR D QVKIRG R++L E++ + P V VVL + Sbjct: 884 G-GRLYRTGDLVRWQPDGCIEYLGRQDHQVKIRGFRIELGEIEARLLAQPGVRQVVVLPH 942 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 S+ ++ +V + + +S + + A L ++L DYM+P +++++++PV NGK+ Sbjct: 943 ET-SAGTRLVGYV-VAQQGAVSCEALRAALAAALPDYMVPAAILQLDSLPVTPNGKL 997 >UniRef50_Q08N46 Cluster: Condensation domain protein; n=3; Stigmatella aurantiaca DW4/3-1|Rep: Condensation domain protein - Stigmatella aurantiaca DW4/3-1 Length = 2000 Score = 103 bits (247), Expect = 3e-21 Identities = 63/178 (35%), Positives = 100/178 (56%), Gaps = 6/178 (3%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHNTHP 200 IG P+ N VY+LDE V G GE+CV G + RGY +G+ RFI +P + Sbjct: 1171 IGRPLKNVQVYVLDEEQNEVPVGVAGELCVGGVGVGRGY-QGRPELTAERFIPHPFSQEA 1229 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LYRTGD ++ G + + GR D QVK+RG R++L+EV+ + P V VV+ Sbjct: 1230 G-ARLYRTGDRARYVEGGELEFLGRMDFQVKLRGFRIELEEVEGVLGKHPGVREVVVVVR 1288 Query: 378 GVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E + ++A+V E+ S++++ + L L +YM+P + +E +P+ + GKV Sbjct: 1289 EDEGGSRRLVAYVVGKQKESAPSSESLRSYLKEKLPEYMVPSAYVRLEALPLALTGKV 1346 >UniRef50_A0NTU6 Cluster: Putative non-ribosomal peptide synthetase; n=1; Stappia aggregata IAM 12614|Rep: Putative non-ribosomal peptide synthetase - Stappia aggregata IAM 12614 Length = 4579 Score = 103 bits (247), Expect = 3e-21 Identities = 61/179 (34%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T PIG P+ N+ VY+LD ++ V +G GE+ + G LARGY D RF+ +P Sbjct: 4032 TPPIGQPLWNSQVYVLDATLQPVADGVSGELYIGGLGLARGYHGRSDLTSDRFVADPF-- 4089 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A++YRTGD K G +++ GR DSQVKIRGHR++ E++ A++++ + VV+ Sbjct: 4090 AGGGARMYRTGDMVYRQKTGELVFLGRGDSQVKIRGHRIEPGEIEAAITSMTNIAQAVVV 4149 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++A+V A + + + L +L DYM+P + + +P+ NGK+ Sbjct: 4150 DRPDGVRGSSLVAYVVPVEGAELKTDALRSVLLRNLPDYMVPGAFVVLPELPLTPNGKL 4208 Score = 93.9 bits (223), Expect = 2e-18 Identities = 56/177 (31%), Positives = 94/177 (53%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG+PI N+ +Y+LD+ ++ V G GE+ + G LARGY D RF+ +P Sbjct: 2494 PIGLPIWNSGLYVLDQALQPVPNGVAGELYIGGVGLARGYQNLADLTSSRFVADPFAG-- 2551 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 + ++YRTGD + G + + GR+D+QVK+RG R++ E++ + V C+V Y Sbjct: 2552 DGWRMYRTGDLVYRAEDGNLFFLGRSDAQVKVRGRRIEPGEIERVLLERSDVAQCLVSVY 2611 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + ++A+V + + + L DYM+P I+ + +P L NGK+ Sbjct: 2612 SDRKATSRLVAYVIGQEGSEPDVQELLRYCADRLPDYMVPAQIDLLPYLPRLPNGKI 2668 Score = 93.5 bits (222), Expect = 3e-18 Identities = 56/178 (31%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 VPIG+P N V +LD+ ++ V G GE+ +AG L GY+ G RF+ +P Sbjct: 1420 VPIGLPRDNCSVRILDDRLQPVGIGMVGELYLAGDCLTLGYLGRTGLTAERFVADPAG-- 1477 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +++YRTGD G++ + GRAD QVKI G R++ QE+++A+ P + C V+ Sbjct: 1478 PAGSRMYRTGDLVRWRSDGLLTFVGRADHQVKINGFRIEPQEIENAIGRQPDIGQCTVVV 1537 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +++A+V + + L+ +L +M+P + +E +P NGK+ Sbjct: 1538 REDRPGEKKLVAYVVGAGAGEPDLERLRERLSETLPAFMVPAHFVLLEHLPFTTNGKL 1595 Score = 92.7 bits (220), Expect = 5e-18 Identities = 61/176 (34%), Positives = 91/176 (51%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG PI + VYLLD+ ++ V +GE GE+ ++G LA GY R K RFI +P P Sbjct: 364 IGNPIRDTRVYLLDDRLQPVTDGEKGELYISGSGLALGYHRQPDKTAERFIASPFG--PA 421 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A LYRTGD + G + GR+D QVKIRG RV+ EV A+ +P V V+ Sbjct: 422 GALLYRTGDVARRMPDGSYEFLGRSDHQVKIRGVRVEPGEVAAALDRLPDVSRSAVVSNR 481 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++ + A+V A + L +L +P ++ ++ +P+ NGK+ Sbjct: 482 RDNGEVYLAAYVVWGTGADRDGPKLMNALAEALPPAFLPSAIVSLDALPLTPNGKL 537 >UniRef50_UPI00005F995E Cluster: COG1020: Non-ribosomal peptide synthetase modules and related proteins; n=1; Yersinia frederiksenii ATCC 33641|Rep: COG1020: Non-ribosomal peptide synthetase modules and related proteins - Yersinia frederiksenii ATCC 33641 Length = 1016 Score = 103 bits (246), Expect = 4e-21 Identities = 55/179 (30%), Positives = 98/179 (54%), Gaps = 5/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN--PH 188 ++PIG PI ++LD+ + V +G G + + G LARGY + +F++ P Sbjct: 325 SIPIGQPIDRTLAFILDDRLLPVAQGVIGHLYIGGEGLARGYWNRDELNKEKFVNVTLPG 384 Query: 189 NTHPNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 ++ P +LY+TGD GV +Y GR D+QVK+RGHR++L+E++ + V Sbjct: 385 DSKP--LRLYKTGDLSCQRPDGVFMYHGRMDNQVKLRGHRIELEEIEFQLLNSELVKAAT 442 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEIETVPVLVNGK 542 V+ E+++P + AF+ + K ++ +L L +YM+P++ + T+P+ GK Sbjct: 443 VILVKNENTDPFLAAFIVPHKPDNFKIKALDKKLHQYLPEYMLPRLFVVNTIPLTSTGK 501 >UniRef50_Q9F9L4 Cluster: Micrococcin P1 peptide synthetase; n=1; Staphylococcus equorum subsp. equorum|Rep: Micrococcin P1 peptide synthetase - Staphylococcus equorum subsp. equorum Length = 915 Score = 103 bits (246), Expect = 4e-21 Identities = 59/179 (32%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++PIG PISN Y+L+E+ + G PGE+C+AG + GY+ + +FI NP Sbjct: 475 SIPIGKPISNIQAYILNEDNNIMGIGVPGELCIAGVGVTAGYLNRPELTQEKFIDNPFGK 534 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 KLYRTGD + G I+Y GR D QVKIRG+R++L E++ + +++ ++ Sbjct: 535 ----GKLYRTGDLAKWNGDGNIIYIGRIDEQVKIRGYRIELGEIESILRQHTHINDVAIV 590 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + I A++ + + +++ L L DYMIP + +++ +PV NGK+ Sbjct: 591 ARPMVDNELSICAYLV--SDDSLDFGSLKTSLGQKLPDYMIPAYMTQLDELPVTSNGKL 647 >UniRef50_Q70AZ6 Cluster: Non-ribosomal peptide synthetase; n=6; Actinomycetales|Rep: Non-ribosomal peptide synthetase - Actinoplanes teichomyceticus Length = 1865 Score = 103 bits (246), Expect = 4e-21 Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG P++N +Y+LD +R V G GE+ +AG LARGY+ D RF+ P Sbjct: 780 LPIGRPMTNRRIYILDAFLRPVAPGVAGELYIAGTGLARGYLSRPDLTAERFVACPFLAG 839 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD ++ G +++ GRAD QVKIRG+RV+L EV+ ++ P V VV+ Sbjct: 840 ---ERMYRTGDLARWNRDGEVVFLGRADDQVKIRGYRVELAEVEAVLAAQPGVREAVVVA 896 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ +V ++ + + I ++ L YM+P VI + ++P+ N KV Sbjct: 897 REDRPGERRLVGYV-VSDAGELDTEQIRQQMARVLPGYMVPVAVIGLVSLPITANSKV 953 >UniRef50_Q0S7I5 Cluster: Non-ribosomal peptide synthetase; n=1; Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide synthetase - Rhodococcus sp. (strain RHA1) Length = 5592 Score = 103 bits (246), Expect = 4e-21 Identities = 61/179 (34%), Positives = 94/179 (52%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 T +G PI N Y+LD +R V +G PGE+ ++G LARGY+ RF+ +P Sbjct: 3835 TPTVGTPIWNTSAYVLDAWLRPVPDGVPGELYISGVGLARGYLDRFALTAERFVADPFEE 3894 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 ++YRTGD + G + + GR D QVKIRGHRV+L E+ A+ + V V+ Sbjct: 3895 S---VRMYRTGDLVRRREDGNLDFLGRTDDQVKIRGHRVELGEIASALEALDDVRQAAVV 3951 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 I+ + ++ L ++L DYM+P VIE++++P+ VNGK+ Sbjct: 3952 VDSGPGGFKRIVGYAVVSTCQPRDVNKYSQALRATLPDYMVPAAVIEVDSLPMTVNGKL 4010 Score = 95.5 bits (227), Expect = 7e-19 Identities = 59/180 (32%), Positives = 94/180 (52%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHN 191 + IG P N +Y+LDE++ V G GE+ GF L RGYV G RF+ NP Sbjct: 788 IATSIGRPNPNTQLYVLDEHLNPVPLGTGGELYAGGFLLGRGYVDAPGLTASRFVANPFA 847 Query: 192 THPNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 + ++LYRTGD G + + GRAD+QVKIRG R++L++V+ + + P V + V Sbjct: 848 N--DGSRLYRTGDLARWAPDGSLDFLGRADNQVKIRGMRLELEDVEAGIVSHPDVRHSAV 905 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + S + A+V ++ + +S L +YM+P + ++ P+ NGK+ Sbjct: 906 VVRETPSGAKYLAAYVVAKQDSVPDVAELRVWASSKLPEYMVPSAFVVLDRFPLTPNGKL 965 Score = 94.3 bits (224), Expect = 2e-18 Identities = 55/179 (30%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNT 194 +VPIG+P SN +Y+LD ++ V G GE+ ++G LARGY+ G RF+ +P + Sbjct: 2311 SVPIGLPTSNTGLYVLDRYLQPVPAGAAGELYLSGPQLARGYLGRPGLSAERFVADPFSR 2370 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +++YRTGD ++ G + Y GR D QVK+RG R++L E++ ++ P V + Sbjct: 2371 --TGSRMYRTGDVARVNADGAVEYVGRVDDQVKLRGFRIELGEIEAQMAACPGVRQAAAV 2428 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +++ +V + + ++ A LT++L ++M+P + + PV +GK+ Sbjct: 2429 VRTDRPGQQQLVGYVVGDAD----VDDVRARLTAALPEFMVPVAFVTVPEFPVGPSGKL 2483 Score = 87.0 bits (206), Expect = 2e-16 Identities = 59/182 (32%), Positives = 94/182 (51%), Gaps = 8/182 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG+P N Y+LD+ ++ V G GE+ +AG LARGY+ D RF+ +P Sbjct: 4889 VPIGIPDPNEQAYVLDDRLQPVPPGVAGELYIAGRGLARGYLGRPDLTSVRFVPSPFGDA 4948 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD G I + GR D QVKIRG R++L E+ A+ + P V V+ Sbjct: 4949 G--TRMYRTGDRARWRADGNIDFLGRVDDQVKIRGFRIELGEIIAALGSHPEVKQSAVVA 5006 Query: 375 YGVESSNPEILAFVTI---NPEARMSAKNIEAELTSSLTDYMIPQVIEI--ETVPVLVNG 539 ++ +VT + ++ + + + L DYM+P ++ + E +P+ NG Sbjct: 5007 -DRSGDIVRLVGYVTSADGHAAGQIDPRAVREHAAARLPDYMVPTLVVVLDEDLPLTPNG 5065 Query: 540 KV 545 K+ Sbjct: 5066 KL 5067 >UniRef50_A7IZW2 Cluster: OciB; n=1; Planktothrix agardhii NIVA-CYA 116|Rep: OciB - Planktothrix agardhii NIVA-CYA 116 Length = 4728 Score = 103 bits (246), Expect = 4e-21 Identities = 65/191 (34%), Positives = 102/191 (53%), Gaps = 16/191 (8%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-- 188 T+PIG I+N +YLLD+N++ V G GE+ + G LA+GY+ + +FI NP Sbjct: 2932 TIPIGKAIANTQIYLLDKNLQPVPIGVVGELHIGGMGLAKGYLNRPELTQEKFIPNPFEK 2991 Query: 189 ---------NTHPNF-AKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV 335 N N +KLY+TGD L G I Y GR D+QVKIRG R++L E++ + Sbjct: 2992 DEVIPPTPLNKDGNEPSKLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEALL 3051 Query: 336 STIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEI 512 + V + V+ + ++A++ PE ++ I L + L DYM+P + + Sbjct: 3052 NQNEDVQSACVIAREDNPGDKRLVAYLVPQPEIILTIDEIRQFLKAKLPDYMVPNAFVIL 3111 Query: 513 ETVPVLVNGKV 545 E +P+ NGK+ Sbjct: 3112 EALPLTPNGKI 3122 Score = 95.1 bits (226), Expect = 9e-19 Identities = 65/197 (32%), Positives = 102/197 (51%), Gaps = 23/197 (11%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P+SN VY+LD ++ V G GE+ + G LARGY+ + +FI NP + Sbjct: 784 VPIGRPLSNTQVYILDAFLQPVPVGVAGELHIGGAGLARGYLNRPELTQEKFIPNPFDEE 843 Query: 198 ----PN--------FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVS 338 PN +KLY+TGD L G I Y GR D+QVKIRG R++L E++ +S Sbjct: 844 GLIPPNPINKGSNESSKLYKTGDLCRYLPDGNIEYLGRIDNQVKIRGFRIELGEIETILS 903 Query: 339 TIPCVDNCVVLCYGVESSNPEILAFV-------TINPEARMSAKNIEAELTSSLTDYMIP 497 V +V+ E+ ++A++ + ++ + L + L +YM+P Sbjct: 904 QHSAVKTAIVIAREDETEQKRLVAYIVPQEGISNRQEQGLLAVTELRQFLKAQLPEYMVP 963 Query: 498 QV-IEIETVPVLVNGKV 545 + +E++P+ NGKV Sbjct: 964 SAFVILESLPLTSNGKV 980 Score = 92.7 bits (220), Expect = 5e-18 Identities = 61/182 (33%), Positives = 99/182 (54%), Gaps = 7/182 (3%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +V IG PI+N Y+LD+N++ G GE+ + G LARGY+ + +FI NP Sbjct: 1869 SVLIGRPIANTKAYILDQNLQPAPIGVKGELHLCGVRLARGYLNRPELTAEKFIDNPFAA 1928 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVST-IPCVDNCVV 368 P F +LY+TGD L G I GR D+QVKIRG R++L E++ ++ + +CV+ Sbjct: 1929 AP-FNRLYKTGDLARYLPNGSIECFGRIDNQVKIRGFRIELGEIEAILNQHLDVQTSCVI 1987 Query: 369 LCYGVESSNPEILAFVTINP--EARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNG 539 + + ++A++ I+ E + L +L YM+PQ + +E++P+ N Sbjct: 1988 IREDLPGQK-YLVAYIVISSHYERIPMISELRQFLAGNLPMYMVPQAFVFLESLPLTTNR 2046 Query: 540 KV 545 KV Sbjct: 2047 KV 2048 Score = 80.6 bits (190), Expect = 2e-14 Identities = 50/138 (36%), Positives = 74/138 (53%), Gaps = 14/138 (10%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-NT 194 + IG PI N VY+LD +++ V G PGE+ + G LARGY+ + +FI NP + Sbjct: 3990 ITIGRPIPNVQVYILDPHLQAVPIGVPGELHIGGAGLARGYLNRPELTAEKFISNPFVSL 4049 Query: 195 HPNF----------AKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVST 341 P +KLY+TGD L G I Y GR D+QVK+RG R++L E++ + Sbjct: 4050 DPPLTPLDKGGEQPSKLYKTGDLARYLPDGQIEYLGRIDNQVKVRGFRIELGEIEAVLGQ 4109 Query: 342 IPCVDNCVVLCYGVESSN 395 P V +V+ +S+ Sbjct: 4110 HPLVQEAIVIARADHASD 4127 >UniRef50_A4KVL5 Cluster: Non-ribosomal peptide synthetase modules; n=1; Sinorhizobium meliloti|Rep: Non-ribosomal peptide synthetase modules - Rhizobium meliloti (Sinorhizobium meliloti) Length = 1112 Score = 103 bits (246), Expect = 4e-21 Identities = 60/178 (33%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +PIG +S Y+LD + + G PGE+ V G + RGY+ G ++I +P + Sbjct: 813 LPIGRAVSQTQAYVLDRSAEPLPYGFPGELYVGGAGVTRGYMNRSGLTAEQYIPDPFSGE 872 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++LYRTGD L G I + GR D+Q+K+ G+R++LQE++ A++ P V V+ Sbjct: 873 PG-SRLYRTGDRASLQSDGNIRFLGRIDNQIKLNGYRIELQEIESALTRHPQVTEAAVVV 931 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + AF T++ +A K + L L YM+P+V I E +PV +GK+ Sbjct: 932 QRSRCGVSRLAAFCTVSGDAATIHKELLLYLRRHLPKYMVPEVFTILEELPVNASGKL 989 >UniRef50_A3KFG6 Cluster: PstD protein; n=1; Actinoplanes friuliensis|Rep: PstD protein - Actinoplanes friuliensis Length = 2370 Score = 103 bits (246), Expect = 4e-21 Identities = 67/179 (37%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 T PIG PI+N+ + +LD +R V G PGE+ +AG NLARGY+ RF+ +P Sbjct: 1832 TAPIGAPIANSAMRVLDPWLRPVPPGVPGELYIAGANLARGYLNRPALTGQRFVPDPLGA 1891 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD D G + Y GR D QVKIRG RV+ EV+ ++T+P V V Sbjct: 1892 -PG-TRMYRTGDLASWDGDGNLRYLGRTDDQVKIRGFRVEPGEVEAVLTTLPGVTRAAVT 1949 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545 + ++A+V P +A + ELT L +++P VI ++ +P+ NGK+ Sbjct: 1950 VREDRPGDKRLIAYVV--PAQDTAA--LHRELTGRLPAHLVPAVIVGLDELPLTPNGKL 2004 Score = 89.8 bits (213), Expect = 4e-17 Identities = 59/178 (33%), Positives = 90/178 (50%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG + N + +LD +R V G PGE+ + G + RGY RF +P+ Sbjct: 765 VPIGTALDNTDLRVLDAALRPVPPGVPGELYLGGTGVGRGYHHRPALTAARFAADPYG-E 823 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LYRTGD + GV+ Y GRAD QVKIRG R++ E++ ++ V VV Sbjct: 824 PG-ARLYRTGDLVRWTETGVLEYLGRADHQVKIRGFRIETGEIEAVLARHDEVAQAVVTV 882 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + + A++ + + A + L YMIP + ++T+P+ NGKV Sbjct: 883 WEPAPGDKRLAAYLVGARGGTLDTAGVRAHAEAVLPGYMIPAAFVVLDTLPLTGNGKV 940 >UniRef50_A0ZF82 Cluster: Non-ribosomal peptide synthase; n=2; Nostocaceae|Rep: Non-ribosomal peptide synthase - Nodularia spumigena CCY 9414 Length = 1394 Score = 103 bits (246), Expect = 4e-21 Identities = 67/180 (37%), Positives = 101/180 (56%), Gaps = 7/180 (3%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG P N +Y+LD + + + G PGE+C+AG LARGY+ + +FI Sbjct: 847 PIGKPWPNIQIYILDAHHQPLPPGIPGELCIAGVGLARGYLNRPELTAEKFIE--VELFG 904 Query: 201 NFAKLYRTGD---FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 ++Y+TGD +GI G + Y GR D QVK+RG R++L E++ + P V VV+ Sbjct: 905 KVKRIYKTGDLARWGI--DGNLEYLGRIDEQVKLRGFRIELGEIESQLLQHPSVKEAVVI 962 Query: 372 CYGVESSNPEILAFVT-INPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 Y E SN ++A+VT I + +N L S L DYMIP Q++ ++ +P+ NGK+ Sbjct: 963 LYKTE-SNQSLIAYVTGITHDLCPELRN---HLKSRLPDYMIPAQIMVLDKLPLTPNGKI 1018 >UniRef50_Q8YTR5 Cluster: Peptide synthetase; n=7; Cyanobacteria|Rep: Peptide synthetase - Anabaena sp. (strain PCC 7120) Length = 2588 Score = 102 bits (245), Expect = 5e-21 Identities = 70/192 (36%), Positives = 105/192 (54%), Gaps = 17/192 (8%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIH----- 179 TVPIG PI+N ++Y+LD++++ V G PGE+ + G +ARGY+ + RFI Sbjct: 772 TVPIGRPIANTHIYILDQHLQPVPIGVPGELYIGGAGVARGYLNRPELTAERFISYSDLG 831 Query: 180 -------NPHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV 335 PH P LY+TGD L G I Y GR D+QVKIRG R++L E++ + Sbjct: 832 SIGYLTPMPHAPCPIPHALYKTGDRARYLRDGTIEYLGRLDNQVKIRGFRIELGEIETVL 891 Query: 336 STIPCVDNCVVLCYGVESSNPEILAF-VTINPEARMSAKNIEAELTSSLTDYMIP-QVIE 509 S V +V+ + + ++A+ V+ NPE ++ L +L DYMIP Q I Sbjct: 892 SQHSEVQAAIVVVTEDTTGDKRLVAYIVSENPE----ITDLRQYLAKNLPDYMIPSQFIT 947 Query: 510 IETVPVLVNGKV 545 ++ +P+ NGKV Sbjct: 948 LDALPLTPNGKV 959 Score = 102 bits (244), Expect = 6e-21 Identities = 69/185 (37%), Positives = 99/185 (53%), Gaps = 10/185 (5%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNT 194 TVPIG PI+N VY+LD ++ + G PGE+ +AG LARGY+ +FI+ T Sbjct: 1830 TVPIGRPINNTQVYILDNHLNPLPVGVPGELYIAGDGLARGYLNQPTLTAEKFINWGLGT 1889 Query: 195 ------HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353 + LY+TGD L G I Y GR D+QVKIRG R++L E++ ++ P V Sbjct: 1890 GDWGLGTTTLSTLYKTGDRARYLADGNIEYLGRLDNQVKIRGFRIELGEIEAVLNQHPAV 1949 Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVL 530 CVV + I F+ ++ + N+ L L DY+IP + +ET+P+ Sbjct: 1950 KECVV----IAREKQLIAYFIALD----NTPDNLREFLQQRLPDYLIPHFFVALETLPLT 2001 Query: 531 VNGKV 545 VNGKV Sbjct: 2002 VNGKV 2006 >UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7; Pseudomonas|Rep: Amino acid adenylation - Pseudomonas fluorescens (strain PfO-1) Length = 5422 Score = 102 bits (245), Expect = 5e-21 Identities = 60/178 (33%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +PIG P+SN +Y+LDE ++ + G GE+ + G +ARGY+ RF+ +P + Sbjct: 862 LPIGRPVSNTRLYILDEQLQPLPLGVAGELYIGGVQVARGYLNLASLTAERFLDDPFSDQ 921 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 PN A+LYRTGD G + Y GR D QVK+RG R++L E+ ++ + V VL Sbjct: 922 PN-ARLYRTGDLCRYRADGNLEYLGRNDDQVKVRGLRIELGEIQTRLTQLATVLAAEVLV 980 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + +P ++A+ T P + + + L L DYM+P + + +P+ NGK+ Sbjct: 981 REDVAGDPRLVAYYTGGP---LEIGELRSHLLEQLPDYMVPTAFVHLAAMPLSPNGKL 1035 Score = 101 bits (242), Expect = 1e-20 Identities = 64/177 (36%), Positives = 96/177 (54%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI+N +Y+LD + V +G GE+ + G +ARGY+ + RF+++P P Sbjct: 5155 PIGKPIANTRLYILDAQQQPVPQGVVGELYIGGVQVARGYLNRPELSAERFLNDPFK--P 5212 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 N ++YRTGD L G I Y GR D QVKIRG R++L E+ ++ I V VVL Sbjct: 5213 N-GRMYRTGDVARYLADGNIEYLGRNDDQVKIRGLRIELGEIQSRLTDISGVQEAVVLAR 5271 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+ T AR+ + L L DYM+P V + + +P+ NGK+ Sbjct: 5272 EDVPGDKRLVAYYT---GARLVIDVLRGHLLEHLPDYMVPAVFVHLGALPLSPNGKL 5325 Score = 98.7 bits (235), Expect = 8e-20 Identities = 61/179 (34%), Positives = 97/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG PISN VY+LD + V G GE+ + G +A GY+ D +F+ +P + Sbjct: 1931 SVPIGGPISNTQVYVLDARQQPVPMGVTGELYIGGQGVALGYLSRPDLTAEKFLQDPFSE 1990 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A LYRTGD L G + GR D QVKIRG R++L E+++ + V +VL Sbjct: 1991 QPG-ALLYRTGDLARWLAPGQLECIGRNDDQVKIRGFRIELGEIENRLLNCDGVKEAIVL 2049 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+ T E + + ++ +L + L +YM+P ++++ +P+ NGKV Sbjct: 2050 ARQDGQEPLRLVAYFT--AEKGVDSASLREQLQARLPEYMVPSAWVQLDALPLNNNGKV 2106 Score = 98.3 bits (234), Expect = 1e-19 Identities = 64/176 (36%), Positives = 98/176 (55%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG P++N +YLLD+ R V G GE+ VAG +ARGY+ D RF+ +P + P Sbjct: 3001 IGRPMANARIYLLDDQQRPVPVGVTGEMYVAGAGVARGYLNRPDLTAERFLTDPFSDQPQ 3060 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD L G I Y GR D QVK+RG RV+L E++ A+++ P V + V L Sbjct: 3061 -ARMYRTGDLARWLADGNIEYLGRNDDQVKLRGVRVELGEIEAALASHPAVQDAVALV-- 3117 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++L + T A + A + L + L +IP + ++ +P+ NGK+ Sbjct: 3118 ---RDGQLLVWFTERAPADIEA--LRNHLQTRLPQALIPAAYVRLDALPLTANGKL 3168 Score = 75.8 bits (178), Expect = 6e-13 Identities = 56/179 (31%), Positives = 92/179 (51%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI+N +Y+LD R V G G++ + G +ARGY+ RF +P Sbjct: 4076 LPIGRPINNTRLYVLDAAKRPVPMGVIGQLFIGGAGVARGYLGLPQLMAERFTPSPFVAG 4135 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LY TGD G + + GR D QVK+RG R++ E++ + + P + VVL Sbjct: 4136 D---RLYATGDLVRYRADGQLEFIGRNDFQVKLRGLRLEPGEIEAQLLSHPALREAVVLV 4192 Query: 375 YGVESSNPEILAFVTINPEA-RMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++A+ T + EA + + + L + L DYM+P + ++++P+ NGKV Sbjct: 4193 -----REERLVAYFTWHAEAGQPGIEALREHLLARLPDYMVPSAFVALDSLPLSPNGKV 4246 >UniRef50_Q9K5M1 Cluster: Peptide synthetase; n=8; Bacteria|Rep: Peptide synthetase - Anabaena circinalis 90 Length = 5060 Score = 102 bits (245), Expect = 5e-21 Identities = 63/189 (33%), Positives = 104/189 (55%), Gaps = 16/189 (8%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI+N +Y+LDE ++ V G PGE+ + G LARGY+ + +FI NP + Sbjct: 782 PIGRPIANAQIYILDEYLQLVPVGVPGELHIGGAGLARGYLNRPELTQEKFIPNPFDNSK 841 Query: 201 -----------NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTI 344 +KLY+TGD L G I Y GR D+QVKIRG R++L E++ +S + Sbjct: 842 FKIPYRNAKDVQNSKLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAVLSQL 901 Query: 345 PCVD-NCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIET 518 V +CV++ + + + ++A++ E + + L + L +YM+P + +E+ Sbjct: 902 GDVQASCVIVREDI-TGDKRLVAYIVPQKEVTPTVTELRQFLKAKLPEYMVPNAFVILES 960 Query: 519 VPVLVNGKV 545 +P+ NGK+ Sbjct: 961 LPLTPNGKI 969 Score = 90.2 bits (214), Expect = 3e-17 Identities = 51/119 (42%), Positives = 71/119 (59%), Gaps = 3/119 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +P+ PI+N VY+LD ++ V G PGE+ +AG +ARGY+ + +FI NP Sbjct: 4354 LPLVGPIANVQVYILDSQLQPVPIGVPGELHIAGVGVARGYLNRPELTQEKFISNPFGP- 4412 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +KLY+TGD G L G I Y GR D+QVKIRG R++L E++ S P V VV+ Sbjct: 4413 ---SKLYKTGDLGRYLADGTIEYLGRIDNQVKIRGFRIELGEIEAVASQHPLVQESVVI 4468 Score = 88.2 bits (209), Expect = 1e-16 Identities = 58/164 (35%), Positives = 88/164 (53%), Gaps = 9/164 (5%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI + VY+LDE+++ V G GE+ V G + RGY+ + RFI NP N + Sbjct: 2945 IGRPIGDLQVYVLDEHLQPVPIGVAGEMYVGGAGVTRGYLNRAELTAQRFISNPFNGNSE 3004 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 LY++GD L G + Y GR D+QVKIRG R++L E++ A+S + V VV+ Sbjct: 3005 -QLLYKSGDLARYLPNGELEYLGRIDNQVKIRGFRIELGEIEAALSQLREVREVVVVARS 3063 Query: 381 VESSNPEILAFVTINPEARMSAKNIE------AELTSSLTDYMI 494 + N ++A+V + S+K E EL S+ +Y + Sbjct: 3064 DQPDNKRLVAYVVPQQKNLESSKKPEKLSTDKVELWPSIAEYYV 3107 Score = 81.4 bits (192), Expect = 1e-14 Identities = 60/191 (31%), Positives = 98/191 (51%), Gaps = 16/191 (8%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP--- 185 +V IG PI+N Y+LD +++ V G GE+ + G LARGY+ + +FI NP Sbjct: 1861 SVLIGRPIANTQAYILDRHLQPVPVGVKGELHLCGVRLARGYLNRPELTEEKFIPNPFSG 1920 Query: 186 --------HNTHP-NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV 335 ++ P ++LY+TGD L G I GR D+QVKIRG R++L E++ + Sbjct: 1921 SRGAEILANSQSPVPSSRLYKTGDLARYLPDGNIECFGRIDNQVKIRGFRIELGEIEAVL 1980 Query: 336 STIPCVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEI 512 + V V+ + ++A+V PE + + L+ +L YM+PQ + + Sbjct: 1981 NQYIDVQTSCVIIREDTPGDKYLVAYVVPYPEKIPTISELRQFLSRNLPLYMVPQAFVFL 2040 Query: 513 ETVPVLVNGKV 545 + +P+ N KV Sbjct: 2041 DFLPLTPNRKV 2051 >UniRef50_Q6HXY8 Cluster: AMP-binding enzyme; n=10; Bacillus cereus group|Rep: AMP-binding enzyme - Bacillus anthracis Length = 2345 Score = 102 bits (245), Expect = 5e-21 Identities = 56/177 (31%), Positives = 100/177 (56%), Gaps = 2/177 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 ++P G+P++N Y+L+ + G G++ + G LA+GY+ + + + +HP Sbjct: 1604 SIPYGMPLANQTYYVLNYEKKMCPVGVIGDLYIGGVGLAKGYLNAE---KKTNEAFVSHP 1660 Query: 201 NFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +F +Y+TGD G + +G I + GR D QVKI+G+RV+L+E+ H + T V++ VV+ Sbjct: 1661 DFGLIYKTGDCGKMHSEGYIEFLGRQDYQVKIQGYRVELEEISHCLLTYKQVEHAVVIDQ 1720 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E+ ++A+V E +S + L L DYMIP + ++ +P+ NGK+ Sbjct: 1721 TDENGIKFLVAYVV--TEQNISTTELRKHLRDHLPDYMIPSYFVYLDQLPLTPNGKL 1775 Score = 91.5 bits (217), Expect = 1e-17 Identities = 62/181 (34%), Positives = 103/181 (56%), Gaps = 7/181 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHNT 194 V IG P N + Y+L++ + G PGE+C+AG +ARGY+ GK +F+ +P Sbjct: 575 VTIGKPNPNYHSYILNKYGQLKPFGIPGELCIAGVAVARGYL-GKSKLTDEKFVPSPFAA 633 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +Y TGD L G + Y GR D QVKIRG+R++L+E++ + P ++ +V+ Sbjct: 634 GE---MMYHTGDLVRWLPNGELEYLGRMDHQVKIRGYRIELREIETQLREYPEINQVIVV 690 Query: 372 --CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542 YG N ++LA ++ + ++S I L+ L ++MIP+ +I++E +P+ NGK Sbjct: 691 DQVYG----NRKLLAAYYVS-DNKVSFGEIRKYLSDKLPEFMIPEKMIQVEEIPLNPNGK 745 Query: 543 V 545 V Sbjct: 746 V 746 >UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces filamentosus|Rep: Peptide synthetase 2 - Streptomyces filamentosus (Streptomyces roseosporus) Length = 7338 Score = 102 bits (245), Expect = 5e-21 Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200 P+G P+ N VY+LD+ +R V G GE+ VAG LARGY+ G RF+ P Sbjct: 2897 PMGRPLRNTCVYVLDDGLRVVPVGVVGELYVAGVGLARGYLGRVGLTAERFVACPFGARG 2956 Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD G + + GRAD QVK+RG RV+L EV+ AV+ P V VV+ Sbjct: 2957 E--RMYRTGDLVRWRVDGTLEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVVVVR 3014 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+VT +S+ + A + L YM+P V+ ++ +P+ NGKV Sbjct: 3015 EDRPGDHRLVAYVTGVDTGGLSSAVMRA-VAERLPAYMVPSAVVVLDEIPLTPNGKV 3070 Score = 100 bits (240), Expect = 2e-20 Identities = 69/181 (38%), Positives = 98/181 (54%), Gaps = 6/181 (3%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHN 191 TVPIG PI N Y+LD +R V G PGE+ +AG LARGY G+ RF+ P Sbjct: 6556 TVPIGRPIWNIRTYVLDAALRPVPPGVPGELYLAGAGLARGY-HGRPALTAERFVACPFG 6614 Query: 192 THPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 P ++YRTGD G + + GRAD QVK+RG RV+L EV+ AV+ P V VV Sbjct: 6615 V-PG-ERMYRTGDLVRWRVDGTLEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVV 6672 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKN-IEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542 + + ++A+VT+ ++ I + L YM+P V+ ++ +P+ NGK Sbjct: 6673 VVREDRPGDHRLVAYVTVGGVGGDGLRSAISGLVAERLPAYMVPSAVVVLDEIPLTPNGK 6732 Query: 543 V 545 V Sbjct: 6733 V 6733 Score = 98.3 bits (234), Expect = 1e-19 Identities = 61/176 (34%), Positives = 94/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG P+ N Y+LD +R V EG GE+ +AG LARGY G RF+ P P Sbjct: 778 IGHPLDNTAAYILDGFLRPVPEGVAGELYLAGTQLARGYAGRPGLTAERFVACPFGA-PG 836 Query: 204 FAKLYRTGDFGILDKG-VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++YRTGD G V+ Y GR D Q+K+RG R++ E++ A++ P V VVL + Sbjct: 837 -ERMYRTGDLVRRSPGGVVEYLGRVDDQIKLRGFRIEPAEIELALAGHPAVAQNVVLLHR 895 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V P + + + L + L YM+P + ++T+P+ NGK+ Sbjct: 896 SATGEARLVAYVV--PGTPVDPRELTGHLAARLPAYMVPSAFVLLDTLPLTPNGKL 949 Score = 98.3 bits (234), Expect = 1e-19 Identities = 66/178 (37%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 VPIG P + +++LD +R V G GE+ VAG LARGY+ G RF+ P Sbjct: 1846 VPIGRPFAGQRMFVLDAALRVVPVGVVGELYVAGVGLARGYLGRAGLTAERFVACPFGA- 1904 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD G + + GRAD QVK+RG RV+L EV+ AV+ P V VV+ Sbjct: 1905 PG-ERMYRTGDLVRWRVDGALEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVVVV 1963 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+VT +S+ + A + L YM+P V+ ++ +P+ NGKV Sbjct: 1964 REDRPGDHRLVAYVTGVDTGGLSSAVMRA-VAERLPAYMVPSAVVVLDEIPLTPNGKV 2020 Score = 97.1 bits (231), Expect = 2e-19 Identities = 66/176 (37%), Positives = 95/176 (53%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHPN 203 IG PI N VY+LD + V G GE+ +AG LARGY+ G RF+ P P Sbjct: 5501 IGTPILNTRVYVLDAALCVVPPGVAGELYIAGDGLARGYLGRAGLTAERFVACPFGA-PG 5559 Query: 204 FAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 ++YRTGD G + + GRAD QVK+RG RV+L EV+ AV+ P V VV+ Sbjct: 5560 -ERMYRTGDLVRWRVDGALEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVVVVRE 5618 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+VT +S+ + A + L YM+P V+ ++ +P+ NGKV Sbjct: 5619 DRPGDHRLVAYVTGVDTGGLSSAVMRA-VAERLPAYMVPSAVVVLDEIPLTPNGKV 5673 Score = 96.3 bits (229), Expect = 4e-19 Identities = 65/179 (36%), Positives = 95/179 (53%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P + +++LD +R V G GE+ VAG LARGY+ G RF+ P Sbjct: 4437 VPIGRPFAGQRMFVLDAALRVVPVGVVGELYVAGVGLARGYLGRVGLTAERFVACPFGV- 4495 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD G + + GRAD QVK+RG RV+L EV+ AV+ P V VV+ Sbjct: 4496 PG-ERMYRTGDLVRWRVDGALEFVGRADDQVKVRGFRVELGEVEGAVAAHPDVVRAVVVV 4554 Query: 375 YGVESSNPEILAFVTINPEARMSAKN-IEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+VT ++ I + L YM+P V+ ++ +P+ NGKV Sbjct: 4555 REDRPGDHRLVAYVTAGGVGGDGLRSAISGLVAERLPAYMVPSAVVVLDEIPLTPNGKV 4613 >UniRef50_Q0YRD8 Cluster: Amino acid adenylation; n=2; cellular organisms|Rep: Amino acid adenylation - Chlorobium ferrooxidans DSM 13031 Length = 1550 Score = 102 bits (245), Expect = 5e-21 Identities = 61/178 (34%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI+N +YLLD N + V G GE+ + G LA GY+ + +FI +P ++ Sbjct: 775 LPIGRPIANTRLYLLDRNRQPVPTGIAGELYIGGVGLASGYLNRPELTAEKFIPDPFSSR 834 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +LY+TGD G + + GR D Q+KIRG R++ E++ A++ IP + + +V Sbjct: 835 PG-ERLYKTGDLVRYRTDGNLEFLGRLDHQLKIRGFRIEPGEIESALTAIPSIHSALVDA 893 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 P + A++ + S + A+L +L +YMIP I +E +P+ VNGK+ Sbjct: 894 RNDAYGQPALAAWL-VAAGTPPSIAGLRADLGRTLPEYMIPTSFIFLEAMPLTVNGKI 950 >UniRef50_A0V6U0 Cluster: Amino acid adenylation domain; n=1; Delftia acidovorans SPH-1|Rep: Amino acid adenylation domain - Delftia acidovorans SPH-1 Length = 2149 Score = 102 bits (245), Expect = 5e-21 Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200 P+GV I + +Y+LD ++ + +G GE+ VAG LARGY+ G RFI NP Sbjct: 750 PVGVAIPDLGLYVLDGSLNLLPQGVAGELYVAGEGLARGYLNRAGLSAERFIANPFTQAG 809 Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 + +LYRTGD +G + Y GRAD QVKIRG R++L EV + P V VVL Sbjct: 810 D--RLYRTGDLVRWSAQGELEYLGRADQQVKIRGFRIELGEVQSQLLAQPEVREAVVLA- 866 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++A+V++ S ++ L +L DYM+P ++ +E +P+ NGKV Sbjct: 867 ---KEGARLIAYVSLRDAVEES--QLKQRLGQALPDYMVPSAIVVLEALPLTANGKV 918 Score = 98.3 bits (234), Expect = 1e-19 Identities = 69/190 (36%), Positives = 102/190 (53%), Gaps = 18/190 (9%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 +G I+ + +LDE +RCV +G GE+ + G LARGY + G RF+ +P P Sbjct: 1833 LGQAIAATRLLVLDEGLRCVPQGVAGELFIGGQGLARGYWQRPGLSAERFVADPF-AGPG 1891 Query: 204 FA--KLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A +LYRTGD + G + Y GR D QVKIRGHR++L EV+ A+ P V VV Sbjct: 1892 AAGERLYRTGDLVRRNADGALEYLGRLDHQVKIRGHRIELGEVEAALLAQPEVREAVVTA 1951 Query: 375 YGVESSNPEILAFVTINPEARMS------------AKNIEAELTSSLTDYMIPQ-VIEIE 515 G S+ ++A V+++ S A + A L S L DYM+P ++ ++ Sbjct: 1952 AG-SGSDTRLVAHVSLHASLHASLHAPLHAGPPLDAAALRARLASGLPDYMLPSAIVVLD 2010 Query: 516 TVPVLVNGKV 545 T+P+ +GKV Sbjct: 2011 TLPLNNSGKV 2020 >UniRef50_Q2SW14 Cluster: Peptide synthetase, putative; n=1; Burkholderia thailandensis E264|Rep: Peptide synthetase, putative - Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 /CIP 106301) Length = 3650 Score = 102 bits (244), Expect = 6e-21 Identities = 59/177 (33%), Positives = 97/177 (54%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI+N +Y+LD + + V G GE+ +AG +ARGY+ + RF+ + P Sbjct: 837 PIGRPIANTRIYILDSHGQPVPIGVAGEIHIAGAGVARGYLNRPELTAERFVSDSFAAAP 896 Query: 201 NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 N A++YRTGD G L G I Y GR D QVKIRG R++L E++ ++ V + VV+ Sbjct: 897 N-ARMYRTGDLGRWLPDGTIEYLGRNDFQVKIRGLRIELGEIEARLARCDGVRDAVVIAR 955 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V + + +L L ++M+P + ++ +P+ NGK+ Sbjct: 956 EDTPGDKRLVAYVLPQSGVALVPAELRRQLAGQLAEHMLPSAFVMLDALPLTPNGKL 1012 Score = 95.5 bits (227), Expect = 7e-19 Identities = 59/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VP G + +Y+L ++R + G PG++ +AG +ARGY+ D +RF+ +PH Sbjct: 1912 VPYGRHLPGQRLYVLSSSLRPLPIGVPGDLWIAGAGVARGYLGQPDLTAYRFVADPHV-- 1969 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD +L G + + GR D QVKIRG R+++ E++ A+ P V+ V Sbjct: 1970 PG-ERMYRTGDRARVLADGNLEFLGRVDDQVKIRGFRIEIGEIEAALGAAPGVERGVATI 2028 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 I A+V A + I L L YM+P ++ I++VP+ NGK+ Sbjct: 2029 V-EHHGRQTIAAYVVARANAVLDHAEIRDALARRLPPYMLPASIVSIDSVPLTRNGKI 2085 Score = 87.8 bits (208), Expect = 1e-16 Identities = 60/178 (33%), Positives = 92/178 (51%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 V IG P +YLLD + R V G GE+ VAG +A GY+ + RF+ +P+ Sbjct: 3353 VTIGRPFPGQRIYLLDRHGRLVPPGAVGEIHVAGEGIAAGYLGAQALTAQRFVADPY--R 3410 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YR+GD G L G + GRAD QVKIRG+R++L E++ A+S++ + V Sbjct: 3411 PG-ERMYRSGDLGRFLPGGRMESLGRADRQVKIRGYRIELGEIECALSSLEGIGGAVADV 3469 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 S + +V A M A+ + L L D M+P +I ++ + NGK+ Sbjct: 3470 REGASGRQLVAWYVA---AADMDAQRVRTALKQRLPDSMMPSALIRVDGFALTANGKI 3524 >UniRef50_Q7BQ70 Cluster: Putative peptide synthetase/polyketide synthase; n=1; Bacillus cereus|Rep: Putative peptide synthetase/polyketide synthase - Bacillus cereus Length = 2562 Score = 102 bits (244), Expect = 6e-21 Identities = 65/185 (35%), Positives = 101/185 (54%), Gaps = 4/185 (2%) Frame = +3 Query: 3 QMHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFI 176 +MH L+ IGVP+ Y+ D++M +G GE+ V G +ARGY+ + RFI Sbjct: 749 EMHSNLSA-IGVPLPTYSCYVFDKHMNPTPKGMQGELYVGGHGVARGYLNRPELNSERFI 807 Query: 177 HNPHNTHPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCV 353 NP+N P+ +LYR+GD IL+ G + Y GR+D QVKIRG+R++ E++H + V Sbjct: 808 QNPYN--PS-ERLYRSGDLVRILENGEMEYIGRSDHQVKIRGYRIETGEIEHHLQQHADV 864 Query: 354 DNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVL 530 VVL E+ A++ + + +S + LT + YMIP + + +P+ Sbjct: 865 KEAVVLSIAF-GEEQELCAYILTDQD--ISQNELRYYLTDKIPSYMIPMYFVLLSEMPLT 921 Query: 531 VNGKV 545 NGKV Sbjct: 922 TNGKV 926 >UniRef50_Q70JX4 Cluster: FenD protein; n=18; Bacillus|Rep: FenD protein - Bacillus amyloliquefaciens Length = 3605 Score = 102 bits (244), Expect = 6e-21 Identities = 62/177 (35%), Positives = 96/177 (54%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTHP 200 PIG PI +N +Y+L +N + G GE+ ++G N RGYV +F+ +P T Sbjct: 791 PIGKPIHHNKMYILSKNRQLQPLGIAGELYISGANTGRGYVNNPALTEEKFLPDPFRTD- 849 Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A +YRTGD L G I Y GR D QVKIRG+R++ +E++ ++ V VL Sbjct: 850 --AVMYRTGDLARLRADGQIEYIGRTDDQVKIRGYRIEPKEIETVLANHHAVKEAAVLIQ 907 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ES E+ A+ +++ S + ++L L DYMIP + ++++P+ NGKV Sbjct: 908 TNESGENELCAYCSVSQATDPS--QLRSDLAKELPDYMIPVKWAFVDSIPLTANGKV 962 Score = 98.3 bits (234), Expect = 1e-19 Identities = 58/178 (32%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNTH 197 + IG PI +++VY+L+ + G GE+C++G LARGY + + F+ +P + Sbjct: 2849 ITIGRPIEHSHVYILNGD-HPQPIGVTGELCISGSGLARGYRNLPKQTAQAFVQDPFQKN 2907 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD L G + Y GR D QVKIRG+RV+L+E++ A++ I V V Sbjct: 2908 ---RRMYRTGDLAKWLPDGTLQYIGRIDEQVKIRGYRVELKEIESALTGIKGVKEAAVTA 2964 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + + E+ A++ E ++ ++ L + + YM+P E +E +PV NGK+ Sbjct: 2965 HTASAGQTELCAYIV--TEEGTESETVQQALRNEMPAYMVPAFFETLEALPVTPNGKL 3020 Score = 86.6 bits (205), Expect = 3e-16 Identities = 58/181 (32%), Positives = 100/181 (55%), Gaps = 4/181 (2%) Frame = +3 Query: 15 FLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH 188 F VPIG+ N +Y+L++ R + G GE+ +AG +ARGY+ + RF+ +P Sbjct: 1822 FHNVPIGISGHNMRLYILNQKKRLLPPGCIGELYIAGTGVARGYLNRPELTEERFLDDPF 1881 Query: 189 NTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 +P ++Y+TGD ++G++ + GR+D QVK+RG+R++ E++ A+ I + Sbjct: 1882 --YPG-ERMYQTGDIARWTEEGLVEWLGRSDGQVKVRGYRIEPGEIEAAIRRIDGIREAA 1938 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGK 542 V E + A++ E R S ++ AEL + L YM+P Q I++ PV +GK Sbjct: 1939 VTA-RTEHGETALYAYI----EGRES-DDVRAELATRLPAYMMPAQFIKMSEWPVTPSGK 1992 Query: 543 V 545 + Sbjct: 1993 L 1993 >UniRef50_Q0YRE2 Cluster: Amino acid adenylation; n=1; Chlorobium ferrooxidans DSM 13031|Rep: Amino acid adenylation - Chlorobium ferrooxidans DSM 13031 Length = 1727 Score = 102 bits (244), Expect = 6e-21 Identities = 64/176 (36%), Positives = 97/176 (55%), Gaps = 2/176 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 +VPIG PI+ +YLLD+ MR G GE+ AG LA GY G+D + H +P Sbjct: 493 SVPIGTPIAGTRIYLLDDAMRPCGAGVIGELYAAGEGLAIGYAAGEDLDARVFVTHPDNP 552 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +LYRTGD + G++ + GR D Q+K+RGHRV+L ++ +S V++ + + Sbjct: 553 E-ERLYRTGDLARFREDGLLEFCGRRDGQIKLRGHRVELPAIEAVLSGCKGVNDSLAMVN 611 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGK 542 G + E++AFV+ + M+ +N AE L YM+P + I E P+ NGK Sbjct: 612 G-KGEGMELVAFVSSSQPDEMAWRNRIAE---RLPLYMMPARFITFEHFPLNANGK 663 Score = 83.8 bits (198), Expect = 2e-15 Identities = 59/178 (33%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V IG PI+N +Y+LD + G PGE+ + G +ARGY+ + RFI +P Sbjct: 1458 VSIGRPIANTSLYILDGRHHPLPVGIPGEIAIGGVQVARGYLNRPELTAERFIADPFT-- 1515 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+ +LY TGD G G I Y GR+D QVKIRG R++ E++HA+ T + VV+ Sbjct: 1516 PD-GRLYLTGDRGRWQPDGSIAYLGRSDWQVKIRGQRIEPGEIEHALETHTDIVRAVVVP 1574 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + E+ A++ + + + L L + MIP + I + +P ++GK+ Sbjct: 1575 VSNQGLD-ELHAWILC--DGSVEQGEVRRFLREQLPESMIPARFILLRELPYTLSGKL 1629 >UniRef50_Q0LKI8 Cluster: Amino acid adenylation; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Amino acid adenylation - Herpetosiphon aurantiacus ATCC 23779 Length = 1127 Score = 102 bits (244), Expect = 6e-21 Identities = 56/138 (40%), Positives = 80/138 (57%), Gaps = 3/138 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 T PIG P++N VYLLD+ + V G GE+ V G +ARGY++ RFI N ++ Sbjct: 807 TPPIGRPLANLQVYLLDQQQQIVPVGVIGEIYVGGVGVARGYLKRPALTAERFIPNQFSS 866 Query: 195 HPNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +LYRTGD G G I + GR D Q+K+RGHR++L E+ ++ P V+ VVL Sbjct: 867 TPG-QRLYRTGDLGRYRVDGQIEFVGRIDQQIKLRGHRIELGEISSLLNAHPAVEQSVVL 925 Query: 372 CYGVESSNPEILAFVTIN 425 + SS ++A+V N Sbjct: 926 VHDHASSTARLIAYVVAN 943 >UniRef50_A3IZB3 Cluster: Amino acid adenylation; n=2; Chroococcales|Rep: Amino acid adenylation - Cyanothece sp. CCY 0110 Length = 1178 Score = 102 bits (244), Expect = 6e-21 Identities = 64/187 (34%), Positives = 99/187 (52%), Gaps = 7/187 (3%) Frame = +3 Query: 6 MHIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIH 179 + ++ T+PIG P+ N Y+LD V G GE+ + G LA GY+ + +FI+ Sbjct: 538 IELYRTIPIGRPLPNRKTYILDTQKNPVPIGVVGELYIGGEGLACGYLNQFELTQEKFIN 597 Query: 180 NPHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVD 356 NP +LY+TGD L G I + GR D+QVK+RG R++L E++ ++ V Sbjct: 598 NPFE----IGQLYKTGDLARYLTDGNIEFLGRIDNQVKLRGFRIELGEIETILTKYSYVR 653 Query: 357 NCVVLCYGVESSNPEILAFVTINPEARMSAK---NIEAELTSSLTDYMIPQV-IEIETVP 524 ++ SN ++A++ +NP S K I+ L L +YMIP V I +ET P Sbjct: 654 EAKIMIREDNYSNQRLVAYIILNPCQTSSLKISQQIKEYLQEKLPNYMIPSVFIILETFP 713 Query: 525 VLVNGKV 545 + NGK+ Sbjct: 714 LTPNGKI 720 >UniRef50_A0UXC9 Cluster: Amino acid adenylation domain; n=2; Bacteria|Rep: Amino acid adenylation domain - Clostridium cellulolyticum H10 Length = 3695 Score = 102 bits (244), Expect = 6e-21 Identities = 63/178 (35%), Positives = 102/178 (57%), Gaps = 4/178 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+ IG PI+N VY++ E+ G PGE+C++G L+RGY+ + +F+ NP+ Sbjct: 2316 TIDIGKPIANTQVYIVSESGNLQPIGIPGELCISGDGLSRGYINRPELTLEKFLENPY-- 2373 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P K+YRTGDF L G I Y R D QVK+RG+R++L E++ + V VV Sbjct: 2374 MPG-KKMYRTGDFVKWLPDGNIEYIRRIDHQVKLRGYRIELGEIEELLLKYSGVREAVVD 2432 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGK 542 G +S + ++ A+VT + + ++ ++ L + L YMIP ++ +E +P+ NGK Sbjct: 2433 VKGEDSESRKLGAYVTADRD--LTEVELKKYLENELPQYMIPTYIMVLEELPLTPNGK 2488 Score = 92.3 bits (219), Expect = 7e-18 Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 3/177 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 +PIG PISNN V +LD + G PG++ ++G N+ RGY + ++ R + + + Sbjct: 3385 IPIGKPISNNKVLILDSCKKMCPIGIPGDIYISGLNVTRGYYKDEEKTREVFTLYGEKGS 3444 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHA-VSTIPCVDNCVVLCY 377 +YRTGD G L G I Y GR D +K+RG+R+++ E+++ + + VV Sbjct: 3445 I--IYRTGDVGRYLSDGTIEYLGRKDGMIKVRGYRIEIGEIENVLLQNEEIIQAAVVAKK 3502 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E+S +++ + T E + + + L L DYMIP Q I +E + + NGK+ Sbjct: 3503 SGETS--KLICYYTAPRE--HTYEELRGCLEKKLPDYMIPAQFIWLEKMILTPNGKI 3555 >UniRef50_A0JZK7 Cluster: Amino acid adenylation domain; n=1; Arthrobacter sp. FB24|Rep: Amino acid adenylation domain - Arthrobacter sp. (strain FB24) Length = 3524 Score = 102 bits (244), Expect = 6e-21 Identities = 61/178 (34%), Positives = 97/178 (54%), Gaps = 6/178 (3%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 +G ++N+ Y+LD + V GE+ VAG NLARGYV G RF+ +P P+ Sbjct: 789 LGDSVANSRHYILDSGLNPVPVNAIGELYVAGINLARGYVDQPGLSAERFVADPFV--PD 846 Query: 204 FAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +++YRTGD L G + + GR D+QVKIRG R++L E++ A+ + VD V Sbjct: 847 GSRMYRTGDVVRRLPDGTLEFRGRMDAQVKIRGFRIELAEIEEALRGLAGVDQAAVTVSK 906 Query: 381 VESSNPEILAFVTI--NPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++L FVT E + + ++ L DYM+P +++I +P+ NGK+ Sbjct: 907 NRAGYDQLLGFVTPAGGLEDELDVAELRRQVRRQLPDYMVPASIVQITAIPLTPNGKL 964 Score = 83.8 bits (198), Expect = 2e-15 Identities = 58/179 (32%), Positives = 92/179 (51%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 T IG I N Y+LD+ + V G PGE+ +AG ARGY + G+ RF+ NP Sbjct: 1861 TPTIGRGIGNTDAYVLDQFLAPVPAGVPGELYLAGPGEARGYDQRPGETAARFVANPFVA 1920 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + +++YRTGD G + + R D QVK+RG R++L E++ AV++ P V V + Sbjct: 1921 --DGSRMYRTGDLVRRAADGSLEFLSRTDDQVKVRGFRIELGEIEAAVASHPDVSRAVAV 1978 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 G + ++A+ T S + L DYM+P V + + +P+ +GK+ Sbjct: 1979 ADGDPAH--RVVAYYT----GAASPAELRGVAGEKLPDYMVPAVFMNVPAIPLTAHGKL 2031 Score = 83.0 bits (196), Expect = 4e-15 Identities = 61/181 (33%), Positives = 95/181 (52%), Gaps = 9/181 (4%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHNTHP 200 +G P + +Y+LD ++ V G GE+ VAG LARGY RG+ RF+ +P Sbjct: 2983 LGQPTAATRLYVLDARLQHVTAGAAGELYVAGPQLARGY-RGRPDLTSERFVADPFAGRG 3041 Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD G +++AGR D Q+KIRG RV+ EV+ AV + V VV Sbjct: 3042 E--RMYRTGDVVYRHADGRLVFAGRNDDQLKIRGFRVEPGEVERAVRSTKGVREAVVRA- 3098 Query: 378 GVESSNPEILAFVT-INPEARMSAK---NIEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542 V + ++A+V N A A+ + + + DYM+P V+ ++ +P+ +GK Sbjct: 3099 AVNDAGTRLVAYVVPANSPAMADAELSDVVRTHVRGLVPDYMVPSAVVVLDKIPLTQHGK 3158 Query: 543 V 545 V Sbjct: 3159 V 3159 >UniRef50_Q8YTR8 Cluster: Peptide synthetase; n=2; Nostocaceae|Rep: Peptide synthetase - Anabaena sp. (strain PCC 7120) Length = 2459 Score = 101 bits (243), Expect = 8e-21 Identities = 64/182 (35%), Positives = 102/182 (56%), Gaps = 7/182 (3%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T PIG I+N VY+LD++++ V G PGE+ +AG +ARGY + + RFI+ Sbjct: 796 TPPIGRAIANTQVYILDKHLQPVPVGVPGELYIAGAGVARGYWQRPELTAERFINQQSTV 855 Query: 195 HPNFAK---LYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNC 362 + + LY+TGD L G I Y GR D+QVKIRG+R++L E+D +S P + Sbjct: 856 NSQQSTVNTLYKTGDRVRYLPDGNIEYLGRLDNQVKIRGYRIELGEIDALLSQYPEIQES 915 Query: 363 VVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539 VV+ S + ++A++ P+ ++ ++ LT L YMIP + ++ +P NG Sbjct: 916 VVIASETSSGDKNLVAYIA--PK-NINIADLRHYLTDKLPGYMIPAHFMTLDALPRNPNG 972 Query: 540 KV 545 K+ Sbjct: 973 KI 974 Score = 80.6 bits (190), Expect = 2e-14 Identities = 51/171 (29%), Positives = 86/171 (50%), Gaps = 11/171 (6%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIH----- 179 ++P G ++N VY+L+ ++ GE+ ++G +A+GY + + +FI Sbjct: 1877 SIPYGYSLTNQQVYVLNHSLEPCPTWAIGEIYISGLGVAKGYWQNPELTAEKFIQLDMGE 1936 Query: 180 --NPHNTHPNF-AKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIP 347 P HP LY+TGD G L G I + GR D QVKI G+R++L E++ A+ P Sbjct: 1937 NFPPTPLHPYTPTPLYKTGDLGRYLSDGTIEFLGREDFQVKINGYRIELGEIEAALQQHP 1996 Query: 348 CVDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ 500 + VV G S +++A++ + PE S + +SS D+ + Q Sbjct: 1997 AITQAVVTTAGNALSQQQLVAYLVLQPEVIASQNTLN---SSSQLDFKLQQ 2044 >UniRef50_Q8CQA8 Cluster: Surfactin synthetase; n=14; Staphylococcus|Rep: Surfactin synthetase - Staphylococcus epidermidis (strain ATCC 12228) Length = 2400 Score = 101 bits (243), Expect = 8e-21 Identities = 61/178 (34%), Positives = 99/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG+PIS VY++ N C G PGE+C+ G LA+GY+ RFI +P N Sbjct: 742 IPIGLPISGTTVYVMQGNRIC-GVGVPGELCIGGAGLAKGYLNQPKLTAERFIQSPFNNE 800 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 LYR+GD L + G I Y R D QVKIRG R++L E++ A+ I ++ VV+ Sbjct: 801 ----MLYRSGDLVRLQEDGYIDYISRIDKQVKIRGFRIELSEIEKALEAIRDINKAVVI- 855 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + +I+A+ S ++ L+ +L +YM+P ++++ +P+ +NGK+ Sbjct: 856 VREQDQDKQIVAY--YEASQLKSTGQLKDILSETLPEYMVPVHFMKVDRIPITMNGKL 911 Score = 91.9 bits (218), Expect = 9e-18 Identities = 55/179 (30%), Positives = 97/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T+PIG P++N ++++ C G PGE+C+AG +L GY+ + +FI+NP Sbjct: 1758 TIPIGKPLANVDIFIMSGGKLC-GVGIPGELCIAGESLTSGYLNRPELSAEKFINNPFGP 1816 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LYR+GD ++ G I + GR D QVK+ G+R++L E+++ ++++ V + VV+ Sbjct: 1817 ----GQLYRSGDLARLMPDGQIEFLGRIDKQVKVHGYRIELGEIENIINSVDTVTDSVVI 1872 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVI-EIETVPVLVNGKV 545 + E+L + ++ +I L L YMIP+ + I +P+ N KV Sbjct: 1873 L--AKQGEREVLHAYYVG--SQEDENHISQHLNQYLPKYMIPKTLTAISEIPLTGNDKV 1927 >UniRef50_Q63CQ6 Cluster: Multifunctional nonribosomal peptide synthetase; n=1; Bacillus cereus E33L|Rep: Multifunctional nonribosomal peptide synthetase - Bacillus cereus (strain ZK / E33L) Length = 3044 Score = 101 bits (243), Expect = 8e-21 Identities = 61/180 (33%), Positives = 103/180 (57%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 + +PIG P+SN VY+L +N C +G GE+C++G +A+GY+ FI P Sbjct: 760 VNIPIGKPVSNYKVYILHKNDLCA-QGILGEICISGRGVAKGYLNNSKLTEEVFIRCPAI 818 Query: 192 THPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 T +YRTGD G ++ G + GR D QVKIRG RV+LQE++ + + V VV Sbjct: 819 TDE---VIYRTGDIGFINPDGEVELVGRMDEQVKIRGFRVELQEIESTLKGVEGVKEAVV 875 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++ N + L + + +++ I+ L++ L +YM+P+ +I ++ +P+L NGK+ Sbjct: 876 V--RQKNLNDDFLVAYFVG-DKKVNDLIIKDNLSNRLPEYMVPEFIIRLDEIPLLPNGKI 932 Score = 80.2 bits (189), Expect = 3e-14 Identities = 54/178 (30%), Positives = 93/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197 V +G PI N ++++EN + V G GE+ V G +A GY+ + +F+ +P+ Sbjct: 2262 VLVGKPILNTSAFIMNEN-KLVGIGMIGELFVGGHGVATGYLNNEKLSKEKFVDHPYEEG 2320 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 LY+TGD + G I GR QVKIRG R++L E++ + + + + VV+ Sbjct: 2321 E---VLYQTGDLARWNADGNIELFGRIGEQVKIRGFRIELGEIESYIRQVKDITDSVVV- 2376 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 +I+A+ T E +S ++ L+ L DYM+P+ I++ +P +NGK+ Sbjct: 2377 LDTNDRTEKIVAYFTARKEIDIS--RLKELLSKKLNDYMVPEHFIQLAGIPKTINGKI 2432 >UniRef50_Q63CQ5 Cluster: Multifunctional nonribosomal peptide synthetase; n=1; Bacillus cereus E33L|Rep: Multifunctional nonribosomal peptide synthetase - Bacillus cereus (strain ZK / E33L) Length = 2295 Score = 101 bits (243), Expect = 8e-21 Identities = 53/178 (29%), Positives = 107/178 (60%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197 VPIG P+SN +Y++++ G GE+C+ G +++ GY+ +FI NP H Sbjct: 2016 VPIGKPVSNTKLYVINQFGNLCGIGMTGELCITGESVSLGYLNQPILTDEKFIPNPFKKH 2075 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 K+Y+TGD +G + + GR D+Q+K+RG R+++QE++ A+ + + VV+ Sbjct: 2076 ---TKMYKTGDLVRWTTQGTLEFLGRKDNQIKLRGFRIEIQEINAALKAYKGIQDAVVIM 2132 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 G ++ ++ A++ I+ E ++ ++ E++ +L +YM+P+ ++++E +P +NGK+ Sbjct: 2133 RG-QNEEKDLCAYI-ISKE-KIDIDSLRKEISETLPEYMLPRYIVQLEKMPRTLNGKI 2187 Score = 85.8 bits (203), Expect = 6e-16 Identities = 55/178 (30%), Positives = 91/178 (51%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197 V +G PI N +Y++ +N C E GE+CV G + RGY+ +++ P ++ Sbjct: 514 VSVGKPIGNGEIYIVKDNKLCGISME-GELCVGGEGVTRGYLNQPVLTDEKYVVIPEISN 572 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++Y+TGD G + G + GR D QVKI G+R++L E++ + I +++ VV+ Sbjct: 573 ---GRIYKTGDVGYWREDGTLKLLGRRDEQVKINGYRIELSEIESGLRQIEGINDAVVI- 628 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 Y P +AF S I+ L +L YMIP ++++E P V GK+ Sbjct: 629 YDQSEKIPLFVAF--YRGTKFESTNKIKELLRKNLPSYMIPNDIVKVEDFPQTVGGKL 684 >UniRef50_Q9Z5F4 Cluster: Ta1; n=4; Bacteria|Rep: Ta1 - Myxococcus xanthus Length = 2393 Score = 101 bits (243), Expect = 8e-21 Identities = 64/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V IG PI N VY+LD+ M+ V G PGE+ +AG +A GY+ RF+ NP Sbjct: 733 VTIGKPIDNTQVYVLDDRMQPVPIGVPGELWIAGAGVACGYLNRPALTAERFVSNPFT-- 790 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P LYRTGD G + Y GR D QVK+RG R+++ E++ ++ P V NC V+ Sbjct: 791 PG-TTLYRTGDLARWRADGEVEYLGRLDHQVKVRGFRIEMGEIEAQLAGHPSVKNCAVVA 849 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++ +++A+ + I A L L DYM+P V ++ +P+ NGKV Sbjct: 850 KELNGTS-QLVAYCQ-PAGTSFDEEAIRAHLRKFLPDYMVPAHVFAVDAIPLSGNGKV 905 >UniRef50_Q2ANX0 Cluster: Non-ribosomal peptide synthase:Amino acid adenylation; n=1; Bacillus weihenstephanensis KBAB4|Rep: Non-ribosomal peptide synthase:Amino acid adenylation - Bacillus weihenstephanensis KBAB4 Length = 1476 Score = 101 bits (243), Expect = 8e-21 Identities = 61/180 (33%), Positives = 99/180 (55%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 ++VPIGVP N +Y+LD ++R V G GE+ ++G +ARGY +D RFI NP++ Sbjct: 746 VSVPIGVPAQNMKIYVLDSDLRPVPMGVVGEIYISGEGVARGYFNNQDLTRERFIVNPYS 805 Query: 192 THPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 ++Y++GD ++ I Y GR D QVK+RG R++L+E++ + P + VV Sbjct: 806 EK---EQMYKSGDLARFIEGDKIEYLGRKDDQVKVRGFRIELKEIEINLQKYPSIKEVVV 862 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + N + A+ T N A++ + L L YMIP I ++ +P+ NGK+ Sbjct: 863 IDQEDYDGNHYLCAYYTEN--AKVKTSELFRFLKEILPVYMIPSYFIVLKEIPLTFNGKL 920 >UniRef50_Q1D8L0 Cluster: Non-ribosomal peptide synthetase; n=1; Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide synthetase - Myxococcus xanthus (strain DK 1622) Length = 1555 Score = 101 bits (243), Expect = 8e-21 Identities = 60/178 (33%), Positives = 93/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197 VPIG PI+N Y+LD R + G GE+ + G + RGY D RF+ +P ++ Sbjct: 1256 VPIGTPIANTQFYILDAQQRPLPIGAAGELYIGGEGVVRGYHHRPELDRERFVPDPFSSQ 1315 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YRTGD G++ Y GR D QVK+RG R++L E++ + P V VV+ Sbjct: 1316 PG-AQMYRTGDAARWRHDGLVEYIGRLDHQVKVRGFRIELGEIESRLGEHPAVRETVVIV 1374 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A++ P +A + L + L +YM+PQ + + T P N KV Sbjct: 1375 REDIPGDKRLVAYLIAKPGEPPAADALREFLRTRLPEYMVPQSFVTLSTFPQTPNKKV 1432 >UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1; Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide synthase - Myxococcus xanthus (strain DK 1622) Length = 5741 Score = 101 bits (243), Expect = 8e-21 Identities = 57/178 (32%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD +R + G PGE+ + G +ARGY + RF+ +P +++ Sbjct: 1838 VPIGTPIANTSLYVLDAELRPLPVGVPGELYIGGMGVARGYHARPELTAERFLPDPASSN 1897 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A++YRTGD G + + GR D Q+K+RG RV+ E++ ++ V VV+ Sbjct: 1898 AG-ARMYRTGDRARWRADGTVEFLGRVDHQLKVRGFRVEPGEIESVLARHSDVAQAVVVA 1956 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V P +S + + A SL ++M+P + ++ +P+ NGKV Sbjct: 1957 REASAGGARLVAYVVARPGTALSVEALLAFSRRSLPEHMVPSAFVPLDALPLTPNGKV 2014 Score = 99.1 bits (236), Expect = 6e-20 Identities = 63/178 (35%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N +Y+LD +R V G PGE+ + G LARGY + D RF+ + Sbjct: 2899 VPIGRPIANARMYVLDARLRPVPAGVPGELYIGGAPLARGYWQRPDLTAERFLPDAFAAQ 2958 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YRTGD L G I Y GR D QVK+RG R++L E++ +S P V V Sbjct: 2959 PG-ARMYRTGDQARFLANGAIEYLGRLDDQVKLRGFRIELGEIEAVLSLHPGVRAAAVAI 3017 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V + P + A + A L L ++M+P + ++ +P+ +GK+ Sbjct: 3018 REDVPGDRRLVAYV-VAPSGDV-ASELRAFLGERLPEHMVPSAFVTLDALPLSPSGKL 3073 Score = 96.7 bits (230), Expect = 3e-19 Identities = 64/183 (34%), Positives = 100/183 (54%), Gaps = 7/183 (3%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHN 191 +++PIG P++N Y+LDE+M V G GE+ + G LA GY+ RF+ NP + Sbjct: 4375 VSIPIGRPLANTVQYVLDEDMAPVPPGGVGELWLGGDGLAWGYLGQPALTAERFVPNPFS 4434 Query: 192 THPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 P +L+RTGD +L G + + GR D+QVK+RG RV+ EV+ A+ P V VV Sbjct: 4435 ERPG-TRLFRTGDRVRLLADGAVTFEGRVDAQVKVRGFRVEPGEVEAALLRHPDVRQAVV 4493 Query: 369 LCYGVES-SNPEILAFVTINPEARMSAKN--IEAELTSSLTDYMIPQV-IEIETVPVLVN 536 L E+ + ++A+V EA + + + L + L YM+P + + +P+ N Sbjct: 4494 LAREDEAGGSRRLVAYVVPTAEAAATPEPSLLRTFLAAHLPAYMVPAAFMVLGRLPLTPN 4553 Query: 537 GKV 545 GKV Sbjct: 4554 GKV 4556 Score = 94.7 bits (225), Expect = 1e-18 Identities = 56/178 (31%), Positives = 92/178 (51%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 +PIG PI+N VY++D +R V G PGE+ + G LA GY + RF+ NP + Sbjct: 5434 IPIGRPIANTRVYVVDAALRPVPVGVPGELLIGGDGLAWGYQGRPELTAERFVPNPFGSE 5493 Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD + G + + R D QVK+RG+RV+ EV+ A+ P V VV+ Sbjct: 5494 AG-GRLYRTGDSVRYREDGTLEFLERLDGQVKVRGYRVEPGEVEEALRLHPSVAEAVVVA 5552 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+ + + + L SL ++M+P ++ + +P+ GK+ Sbjct: 5553 RPDPAGGKRLVAYAVPRAGETLDPRGLRGFLAESLPEFMVPSTLVPLMALPLTPVGKL 5610 Score = 34.7 bits (76), Expect = 1.4 Identities = 21/86 (24%), Positives = 36/86 (41%), Gaps = 1/86 (1%) Frame = +3 Query: 72 ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPNFA-KLYRTGDFGILDK 248 E R GE+ V+G ++A GY + + + RTGD G+L Sbjct: 411 ETRRACPPERVGEIWVSGPSVAHGYWERPEESEAAFGARLADSDSGPRFLRTGDLGLLKD 470 Query: 249 GVILYAGRADSQVKIRGHRVDLQEVD 326 G + GR + +RG + Q+++ Sbjct: 471 GELFVVGRRKDLIILRGRNLHPQDLE 496 >UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8; Bacteria|Rep: Non-ribosomal peptide synthase - Myxococcus xanthus (strain DK 1622) Length = 3906 Score = 101 bits (243), Expect = 8e-21 Identities = 63/185 (34%), Positives = 101/185 (54%), Gaps = 10/185 (5%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVPIG P+SN VY++D + V G GE+ + G ++RGY+ + RFI NP ++ Sbjct: 3595 TVPIGRPVSNTEVYIVDAHGTPVPMGAAGELLIGGEGVSRGYLHRPELTAERFIPNPFSS 3654 Query: 195 HPNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A+LYRTGD G +L + GR D QVKIRG+R++L EV+ + P + V+ Sbjct: 3655 RPG-ARLYRTGDACRYQPGGVLEFLGRIDQQVKIRGYRIELGEVEAVLREHPALREAAVV 3713 Query: 372 CYGVESSNPEILAFVTIN----PEARMSA--KNIEAELTSSLTDYMIPQV-IEIETVPVL 530 + ++A++ + P + A ++ A L L +YM+P + +E +P+ Sbjct: 3714 ARTQDDDAARLVAYLVPSQRDTPLENLQALVAHVRAFLRERLPEYMVPSAFVPLEALPLN 3773 Query: 531 VNGKV 545 +GKV Sbjct: 3774 ASGKV 3778 Score = 101 bits (242), Expect = 1e-20 Identities = 60/179 (33%), Positives = 96/179 (53%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG PISN +++L+ + V G PGE+C G LA GY+ RFI +P + Sbjct: 2532 VPIGRPISNTRIHVLNAALEPVPVGAPGELCAGGDGLALGYLNDPALTAQRFIPDPFSPV 2591 Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+LYRTGD +L G + + GR D QVK+RG R++ E++ A++ P V V+ Sbjct: 2592 PG-ARLYRTGDRCHVLPDGRVEFLGRVDEQVKLRGFRIEPGEIEAALALHPTVHEARVMA 2650 Query: 375 YGVESSNPEILAFVTINPEARM-SAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 +++A++ P + A+++ L + L +M+P + + P+ NGKV Sbjct: 2651 REDGPGEKQLVAYLVARPSRELPPAEDLRRYLQARLPVFMVPSAFVTLAAFPLTANGKV 2709 Score = 97.5 bits (232), Expect = 2e-19 Identities = 59/178 (33%), Positives = 93/178 (52%), Gaps = 4/178 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVPIG P++N +Y+LD + + G PGE+ + G + RGY+ D RF+ + Sbjct: 1472 TVPIGQPVANTALYVLDTRLAPLPVGVPGELYIGGVQVGRGYLGRPDLTAERFVPDGFAR 1531 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 ++YRTGD +L G + Y GR D QVK+RGHR++L E++ + P V VVL Sbjct: 1532 EEGM-RMYRTGDRARVLPDGSLEYLGRLDHQVKVRGHRIELGEIEATLEQHPAVQQAVVL 1590 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGK 542 + +++AF++ A A + L L +M+P I I +P+ +GK Sbjct: 1591 ARTAVGDDVQLVAFISHRGHAPTPA-TLRDFLAERLPGFMVPSHIGILAELPLGPSGK 1647 Score = 40.3 bits (90), Expect = 0.028 Identities = 32/158 (20%), Positives = 66/158 (41%), Gaps = 3/158 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVR-EGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 V G + + ++D R ++ +GE GE+ ++G ++A+GY + + Sbjct: 381 VSSGTQLPTQSLVVVDPQARTLQADGEVGEIWMSGPSVAQGYWGRPEETERVFQARLARG 440 Query: 201 NFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAV-STIPCVDNCVVLCY 377 RTGD G L G + GRA + IRG Q+++ + P + + Sbjct: 441 E-GPFLRTGDLGFLRDGQLFVTGRAKDLIIIRGRNHYPQDLEQTTEQSHPAIRPGCSAAF 499 Query: 378 GVESSNPEILAFV-TINPEARMSAKNIEAELTSSLTDY 488 V+ E LA ++ +S ++ + ++ ++ Sbjct: 500 SVDVDGEEHLAVAFEVSARQEVSPDDVATSVQQAIAEH 537 >UniRef50_Q0VZ70 Cluster: Non ribosomal peptide synthase; n=1; Chondromyces crocatus|Rep: Non ribosomal peptide synthase - Chondromyces crocatus Length = 3912 Score = 101 bits (243), Expect = 8e-21 Identities = 57/177 (32%), Positives = 96/177 (54%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200 PIG P+ + +Y+LD ++R V G PG++ + G L RGY+ R+I +P + P Sbjct: 2794 PIGCPLQSTEIYILDAHLRPVPVGVPGDLYIGGAKLTRGYIHRPALTAERYIPHPFSDRP 2853 Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LY TGD G I + GR D+QVK+RG+R++L EV+ A++ P V VV+ Sbjct: 2854 G-ARLYVTGDIARYQLDGTIDFLGRRDNQVKVRGYRIELGEVEAALNDHPGVREAVVVAQ 2912 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A+ + + + L+ L YMIP V + ++ +P+ GK+ Sbjct: 2913 KDGAGDNRLVAYWAAKSTPPTTTEALRDALSKRLAAYMIPSVFVRMDALPLNATGKI 2969 Score = 91.5 bits (217), Expect = 1e-17 Identities = 48/121 (39%), Positives = 73/121 (60%), Gaps = 3/121 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +PIG P N VYLLD ++ V G PGE+ VA LARGY+ +F+ NP + Sbjct: 795 LPIGRPFYNKRVYLLDARLQPVPVGVPGEIYVASPGLARGYINRPAATAEKFLPNPFSET 854 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD L G +++ GR D+QVK+RG R++L+E++ A+ + P V + V+ Sbjct: 855 PG-ERIYRTGDLARYLPDGNLVFLGRVDNQVKLRGLRIELEEIESALKSHPHVGDAAVIV 913 Query: 375 Y 377 + Sbjct: 914 H 914 >UniRef50_A7BKL9 Cluster: Non-ribosomal peptide synthetase; n=2; Beggiatoa sp. SS|Rep: Non-ribosomal peptide synthetase - Beggiatoa sp. SS Length = 627 Score = 101 bits (243), Expect = 8e-21 Identities = 61/179 (34%), Positives = 98/179 (54%), Gaps = 6/179 (3%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG P++N VY+LD + PGEVC+AG +ARGY+ + +FI Sbjct: 330 PIGKPVANYQVYVLDTENALLPINIPGEVCIAGAGVARGYLNRPELTAEKFIEVV--LFG 387 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++Y+TGD L G + Y GR D QVK+RG R++L E++ + P V VV+ Y Sbjct: 388 KRERIYKTGDLARWLPDGNLEYLGRIDHQVKLRGFRIELGEIEAVLCQHPEVKEAVVVLY 447 Query: 378 GVESSNPEILAFVTINPEARMS--AKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + N ++A+V+++ E + A ++ L L DYMIP ++ ++ +P+ NGK+ Sbjct: 448 DAD-DNKRLVAYVSVDKELTQADLASELKNSLKQQLPDYMIPADLMVLDALPLTSNGKI 505 >UniRef50_A5W120 Cluster: Amino acid adenylation domain; n=3; Bacteria|Rep: Amino acid adenylation domain - Pseudomonas putida F1 Length = 5230 Score = 101 bits (243), Expect = 8e-21 Identities = 63/180 (35%), Positives = 102/180 (56%), Gaps = 6/180 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VP+G P++N Y+LD +++ + G GE+ +AG +ARGY R RF+ NP Sbjct: 824 VPLGRPLANMQAYVLDASLQPLSTGCQGELYLAGAGVARGYHRRAAMTAERFVPNPFGAA 883 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + ++YRTGD L G + Y GR D QVKIRG+R++L E+ + P V + V + Sbjct: 884 GS--RVYRTGDLARQLANGQVDYLGRVDHQVKIRGYRIELGEITDTLKRQPRVHDAVAVI 941 Query: 375 YGVESSNPEILAFVTINPEARMS--AKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +G S+ I+A+V + +A S + +A L L DYM+P + + + +P+ +NGK+ Sbjct: 942 HGTGSA-ARIVAYVVPDSQADASQVLADAQAALARQLPDYMLPSRFMALPGMPLTLNGKL 1000 Score = 99.5 bits (237), Expect = 4e-20 Identities = 65/180 (36%), Positives = 95/180 (52%), Gaps = 6/180 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHN--PHNTH 197 +PIG P NN +Y+LD + G GE+CVAG + RGYV DP R PH Sbjct: 3407 LPIGSPTDNNRLYVLDAALELAPLGVTGELCVAGTGVGRGYV--GDPLRTAQAFIPHPCG 3464 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD GV+ Y GR D QVKIRG R++L E++ A+ V VV+ Sbjct: 3465 APGERLYRTGDLARRRADGVLEYVGRVDHQVKIRGFRIELGEIEAALLDSDQVREAVVMA 3524 Query: 375 YGVESSNPEILAFVTINPEARMSA--KNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ P+++A+ + A + ++A L + L DYM+P + + +P+ NGKV Sbjct: 3525 Q-PGANGPQLVAYCVADDAVAADALKQQLKASLKARLPDYMVPVHWVLMARLPLTPNGKV 3583 Score = 91.9 bits (218), Expect = 9e-18 Identities = 64/183 (34%), Positives = 102/183 (55%), Gaps = 10/183 (5%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 P+GVPI + Y+LD ++ V +G GE+ V LARGY++ D RF+ +P P Sbjct: 4937 PMGVPIPDLSWYVLDGDLNPVAKGCIGELYVGRAGLARGYLKRSDLSATRFVPDPFGA-P 4995 Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +LYRTGD GVI YAGR D QVKIRG R++L E++ + P V +VL Sbjct: 4996 G-GRLYRTGDLARYHADGVIEYAGRIDHQVKIRGFRIELGEIEARLQAQPQVREALVLAQ 5054 Query: 378 GVESSNPEILAF------VTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVN 536 ++ +++A+ V + +A + A+ + +L +L DYM+P ++ ++ P+ N Sbjct: 5055 -EGATGQQLVAYLIPAAEVALEQQAGLRAQ-LREQLKEALPDYMVPAHLLLLDRWPLTAN 5112 Query: 537 GKV 545 GK+ Sbjct: 5113 GKL 5115 Score = 85.0 bits (201), Expect = 1e-15 Identities = 60/182 (32%), Positives = 92/182 (50%), Gaps = 9/182 (4%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200 PIG P+ +LD + + G G++ + G LARGY+ G RF+ +P T Sbjct: 1882 PIGQPVGERSACVLDAALGLLPAGVAGQLYLGGAGLARGYLGRPGLTAERFVPDPFGTEG 1941 Query: 201 NFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LYRTGD + G Y GR D+QVKIRG RV+L E++ + V VV+ Sbjct: 1942 --ARLYRTGDQVRLRADGQFDYLGRIDNQVKIRGFRVELGEIEACLLACAEVREAVVVAV 1999 Query: 378 GVESSNPEILAFVTINPEARM-----SAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539 S ++ A++ + + ++A L SL DYM+P + +E +P+L NG Sbjct: 2000 D-GPSGKQLAAYLVLADSIAAHGPAEQREQLKAALRQSLPDYMLPTHWLVLEQLPLLPNG 2058 Query: 540 KV 545 K+ Sbjct: 2059 KL 2060 >UniRef50_A5EHY7 Cluster: Non ribosomal peptide synthase; n=1; Bradyrhizobium sp. BTAi1|Rep: Non ribosomal peptide synthase - Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) Length = 1134 Score = 101 bits (243), Expect = 8e-21 Identities = 62/178 (34%), Positives = 92/178 (51%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPH-NTH 197 P+G P+ N +++LD + + G PGE+C+AG +ARGYV + RF+ NP + Sbjct: 853 PLGWPVDNTELHILDGRLLPMPLGVPGELCIAGIGVARGYVSRPELTRERFVGNPFADGV 912 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+ A+LYRTGD L G I + GR D QVKIRG RV+L E++ + V VV Sbjct: 913 PHMARLYRTGDVARRLPDGAIEFLGRRDFQVKIRGFRVELGEIEAVLLEQSDVAQAVVAR 972 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + E+ + R L L DYM+P +I ++ +P+ NGK+ Sbjct: 973 RATDGR--ELTVAYLVGRNGRPDLARTHERLRQRLPDYMVPDHIIVLDALPLSANGKL 1028 >UniRef50_A3YGI9 Cluster: Amino acid adenylation; n=1; Marinomonas sp. MED121|Rep: Amino acid adenylation - Marinomonas sp. MED121 Length = 1372 Score = 101 bits (243), Expect = 8e-21 Identities = 62/176 (35%), Positives = 100/176 (56%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 +G + + VYLLD+ M V G+ GE+ +AG NL+RGY+ D R++ NP Sbjct: 816 LGNVMGDTQVYLLDQYMNPVISGQVGELYIAGSNLSRGYLNATDLTAGRYLPNPFVAGGR 875 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 F Y++GD + +G I GRAD QVKIRG R++L+E++ +++ V + VL G Sbjct: 876 F---YQSGDLAMRRAEGCIDILGRADQQVKIRGFRLELEEIESLLASHQTVQHSSVLLQG 932 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 E ++AF + + ++A L ++L DYM+P Q+I ++ +P+ NGKV Sbjct: 933 -EGDQAHLVAFAVPYVGGALDEETLKAWLAANLPDYMVPTQLISVKYLPLNANGKV 987 >UniRef50_Q88JT4 Cluster: Antibiotic biosynthesis protein, putative; n=4; Pseudomonas|Rep: Antibiotic biosynthesis protein, putative - Pseudomonas putida (strain KT2440) Length = 923 Score = 101 bits (242), Expect = 1e-20 Identities = 63/178 (35%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VP+G I++ + +++ + V EGE GE+ + L+RGY G +FI NP T Sbjct: 334 VPLGKGIADAQLLVINPANQLVSEGETGEILIRSPYLSRGYWDDPGLTEAKFIANPF-TA 392 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + YRTGD G L G + GRADSQVKIRGHR++L E+++A+ P + CVVL Sbjct: 393 DTADRCYRTGDLGTYLADGSARFLGRADSQVKIRGHRIELAEIENAICRHPHIGQCVVLT 452 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 E ++ ++A+ R A + L+ L DYM+P + + ++ +P+ N KV Sbjct: 453 -NHEGASTRLVAYCVAQQAIR--ADELRQALSGQLPDYMVPALFVFLDALPLTPNAKV 507 >UniRef50_Q6VT95 Cluster: Mixed type I polyketide synthase/nonribosomal peptide synthetase; n=3; Bacteria|Rep: Mixed type I polyketide synthase/nonribosomal peptide synthetase - symbiont bacterium of Paederus fuscipes Length = 8601 Score = 101 bits (242), Expect = 1e-20 Identities = 61/179 (34%), Positives = 99/179 (55%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +V IG PI+N VY+L+ + + V G PGE+C+AG LARGY+ +FI NP Sbjct: 1529 SVDIGTPIANTRVYILNGDDQLVPIGVPGELCIAGDGLARGYLGNPQLTAQKFIANPF-- 1586 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +LYRTGD + GV+ + GR D QVK+RG+R++L +++ ++ P V +V+ Sbjct: 1587 EPG-NRLYRTGDLARWREDGVLEHLGRLDQQVKVRGYRIELSDIETWLNRHPSVAQSLVV 1645 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 + + +V + A +S+ + L L +YM+P + +P++ NGKV Sbjct: 1646 GHEQAGGMLLVAYYVKDSEWASVSSTELRNYLAEHLPEYMVPAFFRALSNMPLMPNGKV 1704 >UniRef50_Q1D3T0 Cluster: Non-ribosomal peptide synthase MxaA; n=2; Cystobacterineae|Rep: Non-ribosomal peptide synthase MxaA - Myxococcus xanthus (strain DK 1622) Length = 1515 Score = 101 bits (242), Expect = 1e-20 Identities = 63/179 (35%), Positives = 94/179 (52%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 T IG P+ N VY+LD N + G PGEV + G +ARGY+ + RF+ +P Sbjct: 839 TPTIGRPVGNTQVYVLDANREPMPVGVPGEVYIGGHGVARGYLGRTELTAERFVTSPFAG 898 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A LYRTGD L G + Y GR D QVK+RG R++L E+ A+ P + + VV+ Sbjct: 899 DAG-AHLYRTGDLARWLPDGQLEYLGRMDHQVKLRGFRIELGEIGAALQEHPGIRDAVVV 957 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ +++A+V + L S L +YM+P V + +E +P+ NGKV Sbjct: 958 VREGPGADKQLVAYVVGRDGKAPEPGALRDHLKSRLPEYMVPFVFVGLEALPLTPNGKV 1016 >UniRef50_Q0SKF9 Cluster: Non-ribosomal peptide synthetase; n=1; Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide synthetase - Rhodococcus sp. (strain RHA1) Length = 8928 Score = 101 bits (242), Expect = 1e-20 Identities = 65/179 (36%), Positives = 94/179 (52%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG P+ N VY+LD + V G GE+ +AG LARGYV D RF+ NP Sbjct: 2108 SVPIGAPVWNTQVYVLDSRLHPVPVGVHGELYLAGIQLARGYVGRSDLTSDRFVANPFGA 2167 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD G I Y GR D QVK+RG R++L EV+ AV P V VV Sbjct: 2168 -PG-QRMYRTGDVVRWRADGNIEYIGRRDFQVKLRGQRIELGEVEAAVLAHPSVAQAVVT 2225 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + E++ ++ +V A + + +L YM+P ++I ++ P+ GK+ Sbjct: 2226 VHRSEATGESLVGYVIPVAGADIDTAVVRDAAAEALPAYMVPTRIIVLDRFPLGATGKL 2284 Score = 87.0 bits (206), Expect = 2e-16 Identities = 55/178 (30%), Positives = 91/178 (51%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 + +G PI +LD ++ V G PGE+ + G LARGY R + RF+ NP Sbjct: 7337 ITLGGPIRGVGELVLDSRLQPVPVGVPGELYITGAGLARGYHRRPELSSQRFVANPFGEA 7396 Query: 198 PNFAKLYRTGDFGILDKG-VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD + Y GR+D QVKIRG R++L E+D+ ++T P V L Sbjct: 7397 GE--RMYRTGDIVRWRADHTVEYVGRSDFQVKIRGFRIELGEIDNEIATFPGVSFAATLG 7454 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 S + ++ ++ N + + A L++ L +M+P V+ ++ +P+ GK+ Sbjct: 7455 VPGPSGDTVLVTYLLPNTAGGVDPAELTAHLSTRLPAHMVPTSVMFLDEIPLTPVGKL 7512 Score = 84.2 bits (199), Expect = 2e-15 Identities = 55/179 (30%), Positives = 91/179 (50%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 TV IG P+ +LD ++ V G GE+ ++G LARGY G RF+ NP+ Sbjct: 4712 TVTIGAPVRGVSEVILDSRLQPVSVGVAGELYISGEGLARGYHARAGLTSERFVANPYGE 4771 Query: 195 HPNFAKLYRTGDFGILDKG-VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + ++YRTGD + Y GR D QVKIRG R++L ++D A++ P V V L Sbjct: 4772 PGD--RMYRTGDLARWRSDHTVEYLGRTDFQVKIRGFRIELGDIDSALAAHPSVAFAVTL 4829 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + + ++++V E+ + ++ + L +M+P I I + +P+ GK+ Sbjct: 4830 GRPGPAGDTVLVSYVLPEAESALEPPELKEWTANLLPAHMVPSSIMILDEIPLTPVGKL 4888 Score = 84.2 bits (199), Expect = 2e-15 Identities = 55/176 (31%), Positives = 92/176 (52%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHPN 203 IG I+ +V++LD + V G GE+ V+G + RGY+ G RF+ +P P Sbjct: 5802 IGRGIAGLHVHVLDRRLHPVPPGTIGEMYVSGDQVTRGYLGRAGLSSSRFVADP--LRPG 5859 Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YRTGD + G + Y GR+D QVKIRG R++L E++ A+ + VVL Sbjct: 5860 -ARMYRTGDLARWNTDGQLEYLGRSDFQVKIRGFRIELGEIESALLRYRGIAQAVVLTRD 5918 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ +V A + + + + LT YM+P ++ ++ +P+ NGK+ Sbjct: 5919 DGHGGHRLIGYVVPESGATVEVSSALEFVGTQLTSYMVPATLVVLDALPLTSNGKL 5974 Score = 83.8 bits (198), Expect = 2e-15 Identities = 56/178 (31%), Positives = 90/178 (50%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 V IG P +LD + V G GE+ V+G LARGY G RF+ NP+ Sbjct: 3168 VTIGRPPMGTGEMVLDSRLHPVPNGVTGELYVSGSGLARGYKDRAGTTAERFVANPYGGL 3227 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A++YRTGD + G + Y GR+D QVKIRG R++L E++ A++ P V VV Sbjct: 3228 G--ARMYRTGDLARWNGAGQLEYLGRSDFQVKIRGFRIELGEIETALTRYPGVARSVVSA 3285 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + ++ ++ A + + + + L YM+P +I ++ +P+ GK+ Sbjct: 3286 HRGSTGANRLVGYLVPTAGAELDPEAVLEFVGGFLAPYMVPSALIVLDELPLTPAGKL 3343 Score = 81.8 bits (193), Expect = 9e-15 Identities = 56/178 (31%), Positives = 88/178 (49%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNTH 197 V IG P + +LD + V G PGE+ + G +ARGY P RF+ +PH Sbjct: 1041 VTIGRPSRGCGLLVLDSRLHPVPRGVPGELYITGDGVARGYHNRSIPTAERFVADPHGA- 1099 Query: 198 PNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD + G + Y GR D QVKIRG R++L E+D V + P V + Sbjct: 1100 PG-ERMYRTGDLARWNAAGQLEYLGRTDFQVKIRGFRIELGEIDAVVRSHPSVAFATTVG 1158 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 S + ++ +V + +I ++L +M+P +V+ + VP+ GK+ Sbjct: 1159 RTAPSGDTVLVTYVLPEDGTDIVVGDILEHAAAALPAHMVPARVMVLREVPLTPAGKL 1216 Score = 72.5 bits (170), Expect = 6e-12 Identities = 53/179 (29%), Positives = 85/179 (47%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197 V IG P +LDE ++ V G PGE+ + G LARGY RF+ P Sbjct: 8394 VNIGAPALGFGSLVLDERLQPVPVGVPGELYITGPGLARGYHNRSALTSERFVACPFG-E 8452 Query: 198 PNFAKLYRTGDFGILDKG--VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD + +G I Y GR D QVK+RG R++L E+D ++ P V + Sbjct: 8453 PG-RRMYRTGDV-VRWRGDHTIEYIGRTDFQVKVRGFRIELGEIDAVLARHPAVAFAATI 8510 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + S + + ++V + + L +M+P V+ ++ +P+ GK+ Sbjct: 8511 GHTGPSGDTLLASYVRAAEGHDLEPAELRTHAADRLPAHMVPSAVVVLDQIPMTPVGKL 8569 >UniRef50_A6P624 Cluster: Nonribosomal peptide synthetase; n=1; Microcystis aeruginosa|Rep: Nonribosomal peptide synthetase - Microcystis aeruginosa Length = 1415 Score = 101 bits (242), Expect = 1e-20 Identities = 66/186 (35%), Positives = 100/186 (53%), Gaps = 14/186 (7%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP------ 185 IGVPI+N VYLLD ++ V G GE+ + G +A+GY+ + +FI NP Sbjct: 846 IGVPIANTQVYLLDSYLQPVPIGIIGELYIGGIGVAQGYLNRPELTDEKFIPNPFIQDYD 905 Query: 186 HNTHPNFA----KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPC 350 P A K+Y+TGD L G I + GR D QVKIRG R++L E++ + P Sbjct: 906 REKFPRNAFYQTKIYKTGDLARYLPDGKIEFLGRIDDQVKIRGIRIELGEIEARICQYPL 965 Query: 351 VDNCVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPV 527 V +CVV Y ++ ++A++ ++ K ++A L + L MIP Q+I ++ P+ Sbjct: 966 VKDCVVAAYQADTGQ-HLVAYLVAQDALSINQKQLKAYLQNYLPISMIPSQIIILDAFPL 1024 Query: 528 LVNGKV 545 NGKV Sbjct: 1025 TSNGKV 1030 >UniRef50_A4FEM4 Cluster: Non-ribosomal peptide synthetase modules; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Non-ribosomal peptide synthetase modules - Saccharopolyspora erythraea (strain NRRL 23338) Length = 1315 Score = 101 bits (242), Expect = 1e-20 Identities = 61/179 (34%), Positives = 98/179 (54%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V IG + V LLDE + V +G+ GE+C+ G +A GYV K RF+ +P Sbjct: 325 VTIGRALPTYTVVLLDEALHPVPDGDVGEICIGGPGVANGYVGLPEKTADRFVEHP--LA 382 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +LYRTGD G + G I Y GRAD++VKIRG RVDL E+D+ + P V V Sbjct: 383 PRGGRLYRTGDLGRTTEDGEIEYLGRADAEVKIRGRRVDLGEIDNVLLEHPAVSGAVT-- 440 Query: 375 YGVESSNPEILAFVTINPEARMS-AKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + + + +++T+ +A ++ + L +YM+P ++++ + +P + +GKV Sbjct: 441 -ALTADGMALASYLTVRGDAGDELIADLHDRARAKLPEYMVPALVDVLDELPTMPSGKV 498 >UniRef50_A0UXD5 Cluster: Amino acid adenylation domain; n=1; Clostridium cellulolyticum H10|Rep: Amino acid adenylation domain - Clostridium cellulolyticum H10 Length = 2508 Score = 101 bits (242), Expect = 1e-20 Identities = 65/178 (36%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNTH 197 V IG PI+N Y+LD N + G PGE+CV+G LA+GY +FI NP Sbjct: 2035 VLIGKPINNTKCYILDRNDKLQPIGVPGELCVSGHGLAKGYFNADKLTAEKFIDNPF--I 2092 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +YRTGD L G I + GR D QVKIRG+R+++ E++H + V VV Sbjct: 2093 PG-ETMYRTGDMARWLPDGNIEFIGRIDQQVKIRGYRIEIGEIEHHLQMHTNVIEAVVTV 2151 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++ + A+ +N A + K +E L+ L +YM+PQ I++++ P NGK+ Sbjct: 2152 NDLDGQK-TLCAYTVLN--ANIKNKELEEYLSVRLPNYMVPQHFIKLDSFPKTPNGKI 2206 >UniRef50_UPI00015978D8 Cluster: NrsC; n=1; Bacillus amyloliquefaciens FZB42|Rep: NrsC - Bacillus amyloliquefaciens FZB42 Length = 3411 Score = 101 bits (241), Expect = 1e-20 Identities = 60/178 (33%), Positives = 101/178 (56%), Gaps = 3/178 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTH 197 ++P G P+SN Y+L+ EN C G GE+ + G +A GY+ K+ H Sbjct: 862 SIPYGYPLSNQTYYVLNYENDPCPI-GVKGELFIGGKGVAEGYLNDKEK---TEASFIDH 917 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+F ++YRTGD G+L +G I + GR D Q+K+RG+RV+L E++ + V N VV+ Sbjct: 918 PDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVRGYRVELGEIESVILEHRQVRNAVVI- 976 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++ N ++L + + + +++ L+ + +YMIP +++IE VP+ NGKV Sbjct: 977 NQKDARNQDVL-YAYVAGHQSLPPTDLKEFLSLKVPEYMIPSYIVQIEEVPLTSNGKV 1033 Score = 101 bits (241), Expect = 1e-20 Identities = 60/178 (33%), Positives = 101/178 (56%), Gaps = 3/178 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTH 197 ++P G P+SN Y+L+ EN C G GE+ + G +A GY+ K+ H Sbjct: 1910 SIPYGYPLSNQTYYVLNYENDPCPI-GVKGELFIGGKGVAEGYLNDKEK---TEASFIDH 1965 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+F ++YRTGD G+L +G I + GR D Q+K+RG+RV+L E++ + V N VV+ Sbjct: 1966 PDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVRGYRVELGEIESVILEHRQVRNAVVI- 2024 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++ N ++L + + + +++ L+ + +YMIP +++IE VP+ NGKV Sbjct: 2025 NQKDARNQDVL-YAYVAGHQSLPPTDLKEFLSLKVPEYMIPSYIVQIEEVPLTSNGKV 2081 Score = 101 bits (241), Expect = 1e-20 Identities = 60/178 (33%), Positives = 101/178 (56%), Gaps = 3/178 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLD-ENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTH 197 ++P G P+SN Y+L+ EN C G GE+ + G +A GY+ K+ H Sbjct: 2958 SIPYGYPLSNQTYYVLNYENDPCPI-GVKGELFIGGKGVAEGYLNDKEK---TEASFIDH 3013 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+F ++YRTGD G+L +G I + GR D Q+K+RG+RV+L E++ + V N VV+ Sbjct: 3014 PDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVRGYRVELGEIESVILEHRQVRNAVVI- 3072 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 ++ N ++L + + + +++ L+ + +YMIP +++IE VP+ NGKV Sbjct: 3073 NQKDARNQDVL-YAYVAGHQSLPPTDLKEFLSLKVPEYMIPSYIVQIEEVPLTSNGKV 3129 >UniRef50_Q3M3K2 Cluster: Amino acid adenylation; n=2; Nostocaceae|Rep: Amino acid adenylation - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 1093 Score = 101 bits (241), Expect = 1e-20 Identities = 64/181 (35%), Positives = 99/181 (54%), Gaps = 6/181 (3%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 ++PIG PI+N+ VY+LD +++ V G GE+ + G LAR Y D RFI +P N+ Sbjct: 796 SIPIGRPIANSQVYILDSHLQPVPIGVTGELYIGGDGLAREYFHRPDLTAERFILHPFNS 855 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++LY++GD L G I Y GR D+QVK+ G R++L E++ A P V VV+ Sbjct: 856 DPQ-SRLYKSGDLARYLPDGEIEYLGRIDNQVKVSGFRIELGEIEIAFLQHPAVKEAVVV 914 Query: 372 C-YGVESSNPEILAFVTINPEARMS-AKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542 + + FV + +S + L L +YM+P+V + +E +P+ NGK Sbjct: 915 VREDIPGEKLLVGYFVAETGQDNLSIISELRQFLKQQLPEYMVPKVFMALEALPLNANGK 974 Query: 543 V 545 V Sbjct: 975 V 975 >UniRef50_Q6WZB2 Cluster: Nonribosomal peptide synthetase; n=1; Streptomyces vinaceus|Rep: Nonribosomal peptide synthetase - Streptomyces vinaceus Length = 2123 Score = 101 bits (241), Expect = 1e-20 Identities = 59/179 (32%), Positives = 100/179 (55%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 +PIG P N VY+LD+ +R V G GE+ V+G +ARGY+ RF+ +P+ Sbjct: 1405 LPIGRPFPNTRVYVLDDELRLVPRGTVGELYVSGAPVARGYLGRPALTADRFLPDPYG-- 1462 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +++YRTGD G +G++ + GR D QV++RGHR++ E++ + P V V + Sbjct: 1463 PPGSRMYRTGDLGRFTGEGLLDFQGRGDFQVQLRGHRIEPGEIETVLCEQPGVTAAVAVV 1522 Query: 375 YGVESSN-PEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +S ++A+ E + + + A+L L YM+P V+ ++ +P+ VNGK+ Sbjct: 1523 RRPDSPEAAHLVAYAVRAEEPHGTDQALRAKLAERLPHYMVPTAVVTMDALPLTVNGKL 1581 Score = 83.8 bits (198), Expect = 2e-15 Identities = 55/179 (30%), Positives = 94/179 (52%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK---DPHRFIHNPHNT 194 V +G P++ Y+LD+ MR + E GEV + G ++ RGY G+ RF+ +P+ Sbjct: 350 VLVGRPMAGATAYVLDDEMRRLAPNEVGEVYLGGASVTRGY-HGRAALTAQRFLPDPYG- 407 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++LYRTGD G + D G + GR D QVK+ G R++ E++ A++ P V + Sbjct: 408 -PPGSRLYRTGDLGRVEDNGELRLLGRIDHQVKLHGRRIEPGEIEAAMTAHPHVSLAAAV 466 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 G + + F T A A+ + L L ++P +++ ++T+P+ NGK+ Sbjct: 467 PAGA-GAGATLTGFFT---GAEADAEELRGFLAQRLPAALVPSRLVALDTLPLSPNGKI 521 >UniRef50_Q5J1Q7 Cluster: NocA; n=1; Nocardia uniformis subsp. tsuyamanensis|Rep: NocA - Nocardia uniformis subsp. tsuyamanensis Length = 3692 Score = 101 bits (241), Expect = 1e-20 Identities = 64/177 (36%), Positives = 90/177 (50%), Gaps = 3/177 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P N YLLD + V +G E+ +AG LARGY R G RF+ +P Sbjct: 1447 VPIGGPTENTRAYLLDRYLAPVPDGVVAELYLAGSGLARGYSRRPGLTGERFLPDPFAGG 1506 Query: 198 PNFAKLYRTGDFGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD + G + + GR D QVK+RGHR++L EV+ A++ P V VL Sbjct: 1507 GQ--RMYRTGDLAVRRDGALHFIGRVDRQVKVRGHRIELDEVESALTAAPGVAEAAVLLR 1564 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 G ++A V PE + + A L L +M+P V+ + +P GKV Sbjct: 1565 G-----GRLVAHVAAPPE--VDGAGLRAHLAGRLPAFMVPSVVVVSRALPRTSTGKV 1614 Score = 75.4 bits (177), Expect = 8e-13 Identities = 59/182 (32%), Positives = 92/182 (50%), Gaps = 8/182 (4%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 V +G P+ VYLLD + + V G GE+ + G LARGY+ G RF+ +P + Sbjct: 2543 VSLGAPLPGARVYLLDPHGQPVPVGVVGELVLGGEVLARGYLGRPGATAERFLPDPFSDV 2602 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A+ YRTGD G + + GRAD QVKI G RV+ EV+ A+ P V C VL Sbjct: 2603 PG-ARAYRTGDLARHRPDGGLEFVGRADRQVKILGVRVEPHEVETALVANPAVAACAVLP 2661 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTD----YMIP-QVIEIETVPVLVNG 539 ++ ++ + + + AE+ +L + M+P +++ +E +PV G Sbjct: 2662 REDARGAVGLVGYL-VPADRDADPGQLRAEVGRALRERLPRAMVPSRLVVLEALPVGPTG 2720 Query: 540 KV 545 K+ Sbjct: 2721 KL 2722 Score = 73.7 bits (173), Expect = 2e-12 Identities = 54/178 (30%), Positives = 86/178 (48%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +P+G P+ N V ++D + R G GE+ V G LARGY+ G+ RF+ + Sbjct: 347 LPLGRPMHNAAVAVVDADGRRAPVGVAGELVVGGVPLARGYLGRPGETAARFVPDWLGLG 406 Query: 198 PNFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD L G I + GR D + K+RGHRVD E++ + P V V Sbjct: 407 PAGGRVYRTGDRARRLPDGRIEFLGRVDDEFKVRGHRVDPAEIESLLHQHPLVGRAAVRL 466 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + ++A++ + + A L L +IP + + ++ P+ NGKV Sbjct: 467 ----ADGAHVVAYL----QGSADPAELRAHLADRLPLAVIPTRWVRLDRFPLTPNGKV 516 >UniRef50_Q1IBI9 Cluster: Putative non-ribosomal peptide synthetase; n=1; Pseudomonas entomophila L48|Rep: Putative non-ribosomal peptide synthetase - Pseudomonas entomophila (strain L48) Length = 1082 Score = 101 bits (241), Expect = 1e-20 Identities = 59/177 (33%), Positives = 96/177 (54%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHP 200 PIG PI N +Y+LD ++ V G GE+ + G + +GY + + RFI +P + HP Sbjct: 807 PIGRPIGNARLYVLDASLGRVPAGVVGEIHIGGLCVGQGYYKDPARTAERFIDDPFDNHP 866 Query: 201 NFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LY+TGD G D G + GR D Q+K+RG R++ EV+ + P V+ +V+ Sbjct: 867 G-ARLYKTGDLGRWDAAGNLHMLGRCDFQLKVRGCRIEAGEVEAVLRQHPAVEQSLVVGA 925 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + +++A+V SA+++ A L DYM+P V ++ +L NGK+ Sbjct: 926 ADGNGQQQLVAYVIAPQRPAPSAQSLRAFCRQHLPDYMVPAAVCLLDAFDLLPNGKI 982 >UniRef50_Q1DCS5 Cluster: Non-ribosomal peptide synthetase; n=1; Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide synthetase - Myxococcus xanthus (strain DK 1622) Length = 2108 Score = 101 bits (241), Expect = 1e-20 Identities = 61/176 (34%), Positives = 91/176 (51%), Gaps = 2/176 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 +P+G P+ N +++LDE G+ GE+C+AG ++RGY + PH HP Sbjct: 336 IPLGRPVRNASMFVLDEAGGICPPGQLGELCIAGQGVSRGYHARPELTAQKFVPHPYHPG 395 Query: 204 FAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+ YRTGD G GV + GR D QVKIRG+RV+ +EV+ + + V+ VVL G Sbjct: 396 -ARAYRTGDLGYQRSDGVFFFRGRVDRQVKIRGYRVEPEEVESRLQALEGVERAVVLPVG 454 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 +S+ ++A V P A + L YM+P I + + P NGK+ Sbjct: 455 ANASSRRLVAHVVGRPGLEPVA--LRRMLARETPAYMLPSRIHVLDAFPRTPNGKI 508 Score = 100 bits (240), Expect = 2e-20 Identities = 65/177 (36%), Positives = 99/177 (55%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG P+++ ++D R + G PGE+C+AG +++ GY+ D RF+ PH HP Sbjct: 1393 PIGRPMTHVEFLVVDPAGRMLGIGTPGELCIAGPSVSLGYLGRPDLTAERFV--PHPRHP 1450 Query: 201 NFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 ++YRTGD G+L G + GRAD QVK+RG+RV+L E++ + P V VVL Sbjct: 1451 G-ERMYRTGDLGVLRGDGNVALLGRADQQVKVRGYRVELGEIERVLLQHPDVHAGVVLLL 1509 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 G + ++ V PE ++ +E+ L + L YM+P Q + E+ P NGKV Sbjct: 1510 G-SGAQATLVGCVIGVPEEALA--GLESWLAARLPHYMVPTQWLAQESFPASANGKV 1563 >UniRef50_Q1D593 Cluster: Non-ribosomal peptide synthetase; n=4; Bacteria|Rep: Non-ribosomal peptide synthetase - Myxococcus xanthus (strain DK 1622) Length = 4528 Score = 101 bits (241), Expect = 1e-20 Identities = 67/180 (37%), Positives = 97/180 (53%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 LTVPIG P+ N VY+LDE MR V G GE+ V G LA GYV + RF+ +P Sbjct: 1858 LTVPIGKPVGNTRVYVLDEGMRPVPVGVRGELYVGGEGLAEGYVGRPEWTAERFVPSPFG 1917 Query: 192 THPNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 ++YRTGD +G +L + GR D QVK+RG+R++L EV+ A+ V Sbjct: 1918 ---EGERVYRTGDEVRWQEGGLLEFLGRRDEQVKVRGYRIELGEVEEALKQHAQVKEAAA 1974 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + G E + A+V + P A ++ + L +YM+P V+ + E +P+ NGKV Sbjct: 1975 VVRG-EGQEKRVEAYV-VAPGGEGGA--LKEYVRQKLPEYMVPSVVVVLEALPLTPNGKV 2030 Score = 101 bits (241), Expect = 1e-20 Identities = 67/180 (37%), Positives = 97/180 (53%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 LTVPIG P+ N VY+LDE MR V G GE+ V G LA GYV + RF+ +P Sbjct: 3972 LTVPIGKPVGNTRVYVLDEGMRPVPVGVRGELYVGGEGLAEGYVGRPEWTAERFVPSPFG 4031 Query: 192 THPNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 ++YRTGD +G +L + GR D QVK+RG+R++L EV+ A+ V Sbjct: 4032 ---EGERVYRTGDEVRWQEGGLLEFLGRRDEQVKVRGYRIELGEVEEALKQHAQVKEAAA 4088 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + G E + A+V + P A ++ + L +YM+P V+ + E +P+ NGKV Sbjct: 4089 VVRG-EGQEKRVEAYV-VAPGGEGGA--LKEYVRQKLPEYMVPSVVVVLEALPLTPNGKV 4144 Score = 94.3 bits (224), Expect = 2e-18 Identities = 58/180 (32%), Positives = 94/180 (52%), Gaps = 4/180 (2%) Frame = +3 Query: 18 LTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHN 191 + VP+G P+ N VY+LD +R V G GE+ G + RGY+ + R++ +P+ Sbjct: 777 VVVPLGRPMGNTRVYVLDGGLRPVPVGVAGELYAGGAQVTRGYLGHPELTAERYVPDPYG 836 Query: 192 THPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 P A++YRTGD L G + + GR D QVK+RG RV+ EV + P V + VV Sbjct: 837 GEPG-ARMYRTGDKVRWLADGRLEFIGRVDFQVKVRGFRVEPGEVATVLRAHPEVRDAVV 895 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + N ++A+ T + + + A L L +M+P ++ ++ +P+ NGKV Sbjct: 896 VAREDVPGNKRLVAYATPSSQPAPDTAALRAFLQQRLPGHMVPSALVVLDALPLTPNGKV 955 Score = 90.2 bits (214), Expect = 3e-17 Identities = 57/179 (31%), Positives = 91/179 (50%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 TVP+G P+ N VY+LD ++R V G GE+ V G + RGYV + R++ +P + Sbjct: 2919 TVPLGRPMGNTRVYVLDRSLRPVPVGVGGELFVGGAQVTRGYVWRPELTAERYVPDPFSM 2978 Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A++YRTGD L G + + GR D QVK+RG RV+ EV + P V + VV+ Sbjct: 2979 EAG-ARMYRTGDKVRWLGDGRLEFIGRTDFQVKVRGFRVEPGEVAAVLRAHPDVQDAVVV 3037 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++ + A + L L +M+P ++ ++ +P+ NGKV Sbjct: 3038 AREEVPGDNRLVGYAVRTARAAPDIAALRGFLQQRLPGHMVPSALVVLDALPLTPNGKV 3096 >UniRef50_Q0S6F2 Cluster: Non-ribosomal peptide synthetase; n=2; Bacteria|Rep: Non-ribosomal peptide synthetase - Rhodococcus sp. (strain RHA1) Length = 6278 Score = 101 bits (241), Expect = 1e-20 Identities = 65/178 (36%), Positives = 91/178 (51%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG P+ N Y+LD +R V G GE+ + G LARGY D RF+ NP T Sbjct: 2091 VPIGAPVWNTQTYVLDGRLRVVPVGVAGELYLGGVQLARGYQGRADLTADRFVANPFGT- 2149 Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD L G + Y GR D QVK+RG RV+L E++ + V VV+ Sbjct: 2150 ---GRLYRTGDRVRWLPSGELEYLGRTDFQVKLRGQRVELGEIEAVLLRREDVAQAVVVL 2206 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 G SS + +V A + + + +L +M+P V+ + +PV VNGK+ Sbjct: 2207 RGDGSSGEYLAGYVVPVAGAVVDERVVRESAAVALPGFMVPSVVVVLAELPVTVNGKL 2264 Score = 79.4 bits (187), Expect = 5e-14 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 5/179 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 + IG PI +LD ++ V G PGE+ +AG LARGY R RF+ +P Sbjct: 4685 ITIGGPIRGVTELVLDPRLQPVPVGVPGELYLAGAGLARGYHRRPALTAERFVAHP--VR 4742 Query: 198 PNFAKLYRTGDF--GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD D+ I Y GR D QVK+RG R++L E+D + + P V L Sbjct: 4743 PG-ERMYRTGDIVRWTADRS-IEYVGRTDFQVKVRGFRIELGEIDSTLMSEPDVGFAATL 4800 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + + + ++++V + + L L +M+P I + E +P+ GK+ Sbjct: 4801 AHRGPAGDTLLVSYVVPASGRSLDPVVLTRHLADRLPSHMVPTSITVLERIPLTAVGKL 4859 Score = 77.0 bits (181), Expect = 3e-13 Identities = 54/180 (30%), Positives = 90/180 (50%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP---HRFIHNPHN 191 T+ +G P+ + +LD ++ V G GE+ VAG LARGY GK RF+ NP Sbjct: 1025 TITVGGPLRGFHEVVLDARLQPVPPGVAGELYVAGDGLARGY-HGKSALTAERFVANPFG 1083 Query: 192 THPNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 P ++YRTGD + L Y GR D QVKIRG R++ E+D + P V + Sbjct: 1084 G-PG-ERMYRTGDVVRWRTDLSLEYLGRIDFQVKIRGFRIEPGEIDTVLHAHPRVRTAMT 1141 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + S + ++++V +++ + + L YM+P ++ ++ +P+ GK+ Sbjct: 1142 MPRTAPSGDTVLVSYVLPAAGHQLATRELIDYAAEQLPTYMVPAAIVVLDEIPMTPVGKL 1201 Score = 71.7 bits (168), Expect = 1e-11 Identities = 50/180 (27%), Positives = 86/180 (47%), Gaps = 5/180 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 +V IG P +LDE ++ V G PGE+ +AG +ARGY RF+ N Sbjct: 5742 SVNIGAPARGFAFLVLDERLQPVPVGVPGELYIAGPGMARGYHNRAALTSERFV--ACNF 5799 Query: 195 HPNFAKLYRTGDFGILDKGV--ILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVV 368 ++YRTGD + + Y GR+D QVK+RG R++L E+D ++ P V Sbjct: 5800 GEPGCRMYRTGDVVRWRESASALEYIGRSDFQVKVRGFRIELGEIDAVLTRHPAVAFAAT 5859 Query: 369 LCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + + S + + ++V + + + L +M+P V+ ++ +P+ GK+ Sbjct: 5860 IGHIGPSGDTVLASYVRAQDGQEVQPAGLRTYASERLPAHMVPSAVVVLDRIPMTPVGKL 5919 Score = 70.5 bits (165), Expect = 2e-11 Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHPN 203 IG + VY+LD + V G GE+ V+G ++RGY+ RF+ +P P Sbjct: 3168 IGRGLPGLRVYVLDGRLHPVPPGVVGEMYVSGAQVSRGYLGRAALTSGRFVADPFT--PG 3225 Query: 204 FAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A++YR+GD G + G + Y GR D QV+++G+R++L EV+ A+ V VV G Sbjct: 3226 -ARMYRSGDLGRWNGHGQLEYLGRNDLQVQVKGYRIELGEVEAALLACEGVAQSVVTARG 3284 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ +V A + I L +M+P V+ ++ +P VNGK+ Sbjct: 3285 -----DRLVGYVVPETGAAIDPAAIIDAAAVRLASHMVPAAVVVLDELPRTVNGKL 3335 >UniRef50_A5FI38 Cluster: Amino acid adenylation domain; n=2; Bacteria|Rep: Amino acid adenylation domain - Flavobacterium johnsoniae UW101 Length = 3395 Score = 101 bits (241), Expect = 1e-20 Identities = 59/178 (33%), Positives = 100/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PISN VY+L++ + G GE+C++G +L+ GY+ ++ +FI NP + Sbjct: 3112 VPIGKPISNVQVYILNDKLNMQPVGVIGELCISGESLSNGYLNNEELTNEKFIENPFKSG 3171 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 K+Y+TGD L G I + GR D QVKIRG+R++L E++ + + + + VVL Sbjct: 3172 ---QKIYKTGDLARWLPDGNIEFMGRIDGQVKIRGYRIELGEIEKQLLSQEGIKHSVVLV 3228 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 ++ + +V+ + + K + L+ L DYMIP ++++ +P+ N KV Sbjct: 3229 KEIKGEKCLVAYYVS---DYELDKKILTENLSKMLPDYMIPAYYVQLDVIPLTTNDKV 3283 Score = 87.4 bits (207), Expect = 2e-16 Identities = 51/173 (29%), Positives = 92/173 (53%), Gaps = 4/173 (2%) Frame = +3 Query: 39 PISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNTHPNFAK 212 PI N V++LDEN V G GE+ +AG + RGY + F++ P N + Sbjct: 581 PIQNFEVHILDENRERVPVGVKGEIYLAGPCVGRGYFNDEKRTKEAFLNGPIEGITNQKR 640 Query: 213 LYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYGVES 389 +Y+TGD + G + + GR D+QVKI GHR++L +++ ++ IP V + + Sbjct: 641 IYKTGDLARFMPNGTMEFIGRNDNQVKILGHRIELDAIENIMAEIPAVKS----VKAIAD 696 Query: 390 SNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 +N +++ ++ ++ + +E +L + L YM+P I + + P+ NGK+ Sbjct: 697 TNKQMIVLYYVS-DSEIDKNFMEEQLLNKLPKYMLPSAFIHMLSFPLTKNGKI 748 Score = 85.0 bits (201), Expect = 1e-15 Identities = 60/176 (34%), Positives = 90/176 (51%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG PI +LDE V G GE+ + G LARGY+ + RFI NP N Sbjct: 1624 IGKPIPTLSCLILDEFKNIVPAGVIGEMYIGGSGLARGYLNRPELTAERFIVNPFNPEE- 1682 Query: 204 FAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LY+TGD G G I Y GR D+QVKIRGHR++L E++ AV D + Sbjct: 1683 --RLYKTGDLGRWQTDGNIEYIGRIDNQVKIRGHRIELGEIE-AVLLGYSSDIRQFVVDT 1739 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E + +IL ++ + + ++ + + L +YM+P + ++ +P+ NGKV Sbjct: 1740 CELNGDKILVAYYVS-DTEVDKASLRSYIQQQLPEYMVPNFFVAMDAIPLTGNGKV 1794 >UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide synthetase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Putative non-ribosomal peptide synthetase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 2385 Score = 101 bits (241), Expect = 1e-20 Identities = 66/179 (36%), Positives = 97/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGK--DPHRFIHNPHNT 194 +V IG P N +Y+LDE+++ V G GE+ VAG L RGYV RF+ +P Sbjct: 1844 SVSIGRPNPNTRMYVLDEHLQPVPVGVQGELYVAGLQLGRGYVNAPALTASRFVADPFG- 1902 Query: 195 HPNFAKLYRTGDFGILDKGVIL-YAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++YRTGD G L + GRAD QVKIRG RV+LQEV+ +S P V VV+ Sbjct: 1903 -PAGERMYRTGDLACWTAGGTLEFRGRADHQVKIRGMRVELQEVESVLSEHPAVRQAVVV 1961 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 S ++A+ T E+ ++ + L L ++M+P V+ + P++ +GKV Sbjct: 1962 TARSRSDVGLLVAYCTTTDES-VTGDGLRGWLRGRLPEHMVPAAVVCLPRFPLMPSGKV 2019 Score = 90.2 bits (214), Expect = 3e-17 Identities = 62/179 (34%), Positives = 94/179 (52%), Gaps = 7/179 (3%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG + YLLDE +R V +G GE+ V G LARGY+ G RF+ +P P Sbjct: 787 IGRGLPGLSTYLLDEALRPVPDGVVGELYVGGAQLARGYLGRPGLTATRFVADPFGA-PG 845 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LYRTGD G + Y GRAD QVKIRG R++ E+ ++T P V C V+ Sbjct: 846 -ERLYRTGDLARRAGDGRLEYVGRADDQVKIRGFRIEPAEISSVLATHPDVSRCAVVARH 904 Query: 381 VESSNPEILAFV---TINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ +V +++P A + L + L ++M+P +E+E++P+ NGK+ Sbjct: 905 GAQGGAYLVVYVVGESVDPAA------LRGYLAARLPEHMVPAAFVELESLPLTGNGKL 957 >UniRef50_A0V6U3 Cluster: Amino acid adenylation domain; n=1; Delftia acidovorans SPH-1|Rep: Amino acid adenylation domain - Delftia acidovorans SPH-1 Length = 4560 Score = 101 bits (241), Expect = 1e-20 Identities = 61/178 (34%), Positives = 100/178 (56%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +PIG P++ +++++D+ MR V G GE+C+ G L+RGY+ G RF+ +P H Sbjct: 2495 LPIGRPLAGRHMWVVDDRMRPVPLGVAGELCIGGPLLSRGYLNRAGLSAERFVADPFG-H 2553 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 A+LYRTGD + +G + Y GR D QVKIRG R++L EV + + V VV+ Sbjct: 2554 DG-ARLYRTGDLVRWNAQGQLEYLGRVDHQVKIRGLRIELGEVQAQLLALDDVREAVVVA 2612 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 G + +LA+V+ + + + L + L DYM+P ++ ++ +P NGK+ Sbjct: 2613 -GEGPAGTRLLAYVSARSGRTLDEQEMRERLATVLPDYMVPGAIMVLDQLPQNANGKL 2669 Score = 100 bits (240), Expect = 2e-20 Identities = 64/179 (35%), Positives = 97/179 (54%), Gaps = 6/179 (3%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHP 200 PIG P+ V++LD ++ V G GE+ + G+ LARGY+ G RF+ +P + Sbjct: 4005 PIGRPVGERTVHILDADLHRVPHGVVGELYIGGYGLARGYLSRHGLTAERFVADPFDG-- 4062 Query: 201 NFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +LYRTGD + G I Y GRAD QVKIRG R++L EV+ AV +P V + VL Sbjct: 4063 GGGRLYRTGDLVREMPDGNIEYIGRADHQVKIRGFRIELGEVEKAVRAVPGVVDAAVLVQ 4122 Query: 378 GVESSNPEILAFVT--INPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + +++A+V A+ + I + L DYM+P + + +P LV+GK+ Sbjct: 4123 DA-GTGKQLVAYVVGEEGTAAQTLVQRIRQQTGEHLPDYMLPAHTLVLPALPRLVSGKL 4180 Score = 91.9 bits (218), Expect = 9e-18 Identities = 59/178 (33%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P+S +L +++ V G GE+ + G LA+GY+ G RF+ +P + Sbjct: 311 VPIGRPVSATKALVLGQDLGLVPAGVAGELYLGGQALAQGYLGRPGLSAERFVADPFDQ- 369 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD D+G + Y GR D QVKIRG R++L E++ + P V VV+ Sbjct: 370 -GGGRLYRTGDLVRWNDEGQLEYLGRLDHQVKIRGFRIELGEIEARLLAQPQVRESVVVA 428 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + + A+V+ + +++A + L L DYM+P ++ ++ +P+ NGKV Sbjct: 429 -RKGPAGMHLAAYVSAHEGQQVTAAELRERLALELPDYMVPASIMVLDRLPLNANGKV 485 Score = 91.5 bits (217), Expect = 1e-17 Identities = 66/181 (36%), Positives = 94/181 (51%), Gaps = 7/181 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG PIS Y+LD MR +G GE+ + G LARGY+ RF+ +P +T Sbjct: 1396 VPIGQPISGIRTYVLDCAMRPAPQGVAGELYLGGIGLARGYLNRPALTAERFVADPLDTQ 1455 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 LYRTGD + +G I Y GR D QVKIRG R++L E++ + P V VV+ Sbjct: 1456 GGL--LYRTGDLVRWNGEGQIEYLGRLDHQVKIRGLRIELGEIEAHLLAQPGVREAVVVA 1513 Query: 375 YGVES--SNPEILAFVTINPEARMS-AKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGK 542 S + ++A+V P+A A+ + L L DYM P ++ + + + NGK Sbjct: 1514 AQATSGAAGARLVAYVA-GPDADAGLAETLRQALAGRLPDYMQPSAIVVLPALALNANGK 1572 Query: 543 V 545 V Sbjct: 1573 V 1573 >UniRef50_Q5YPH6 Cluster: Putative non-ribosomal peptide synthetase; n=1; Nocardia farcinica|Rep: Putative non-ribosomal peptide synthetase - Nocardia farcinica Length = 5961 Score = 100 bits (240), Expect = 2e-20 Identities = 61/181 (33%), Positives = 99/181 (54%), Gaps = 7/181 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P+ N +++LD +R V G PGE+ ++G LARGYV G RF+ +P Sbjct: 840 VPIGAPVFNTRLHVLDSRLRPVPVGAPGELYLSGVQLARGYVARPGLSAERFVADPFG-- 897 Query: 198 PNFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P ++YRTGD + G + Y GR D QVK+RG R++L E++ ++ + V VVL Sbjct: 898 PAGTRMYRTGDLVRWNTSGELEYLGRTDFQVKLRGLRIELGEIEAVLAGVDGVVRAVVLV 957 Query: 375 ---YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542 G + +++A+V + A+ + A +L YM+P + ++ +PV +GK Sbjct: 958 RDDVGSPALGEQLVAYVVAAEPDAVGAEQLRAAALRALPAYMVPAAYVVLDELPVNASGK 1017 Query: 543 V 545 + Sbjct: 1018 L 1018 Score = 93.1 bits (221), Expect = 4e-18 Identities = 60/179 (33%), Positives = 98/179 (54%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNT 194 +VPIG P++N VY+LD+ +R V G PGE+ +AG LARGY D RF+ +P Sbjct: 2965 SVPIGSPVANTRVYVLDDRLRPVPAGVPGELYLAGVQLARGYAGRPDLTADRFVADPFT- 3023 Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P A++YRTGD G + Y GR D QVK+RG R++ E++ A++ + VD VV+ Sbjct: 3024 -PG-ARMYRTGDRVRWSAAGELEYLGRTDFQVKVRGMRIEPGEIEAALTELDGVDQAVVV 3081 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + + ++A++ P + + L L Y++P + ++ P+ +GK+ Sbjct: 3082 -----ARDEHLVAYLI--PAGPVDPDAVRVALARRLPAYLVPAAFVLLDAFPLNASGKL 3133 Score = 89.4 bits (212), Expect = 5e-17 Identities = 62/181 (34%), Positives = 99/181 (54%), Gaps = 7/181 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTH 197 V IG P+ ++LDE +R V G GE+ VAG LARGY R RF+ P Sbjct: 1905 VTIGRPLRGVREWVLDERLRPVPVGVAGELYVAGAQLARGYHGRRATTAERFVACPWA-- 1962 Query: 198 PNFAKLYRTGDF--GILDKG--VILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 P ++YRTGD L G + Y GR D+QVK+RG R++L E++ A++ P V + V Sbjct: 1963 PG-ERMYRTGDLVRWTLASGGRELEYLGRNDAQVKVRGFRIELGEIEAALAARPGVAHAV 2021 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIEI-ETVPVLVNGK 542 V + + ++ A+V + + A +++A L + L +++P I + +T+P+ NGK Sbjct: 2022 VTVHRDPARGDQLAAYVVPSGGHPLDAGDLKAGLRTRLAPHLVPAAITVLDTLPLTPNGK 2081 Query: 543 V 545 + Sbjct: 2082 L 2082 Score = 87.0 bits (206), Expect = 2e-16 Identities = 59/177 (33%), Positives = 93/177 (52%), Gaps = 5/177 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV--RGKDPHRFIHNPHNTHPN 203 IG I V +LD +R V G PGE+ V+G LARGY+ G RF+ +P+ P Sbjct: 4035 IGGAIPGLTVRVLDPRLRPVPVGVPGEIYVSGGQLARGYLGRPGLTAGRFVADPYG--PA 4092 Query: 204 FAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 A+ YR+GD G + + GRAD QV +RG R++L E++ A+ P V V+ Sbjct: 4093 GARAYRSGDLARWTATGELEFLGRADQQVNLRGFRIELGEIEAALLAEPEVTEAAVVVRS 4152 Query: 381 VESSNPEILAF-VTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 I+ + VT P + + + +L ++M+P ++EI+ +P+ VNGK+ Sbjct: 4153 DLVDEARIVGYLVTAGP---VDTAELRERVRRTLPEHMVPAALVEIDRIPLTVNGKL 4206 Score = 79.8 bits (188), Expect(2) = 2e-16 Identities = 50/138 (36%), Positives = 75/138 (54%), Gaps = 3/138 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY--VRGKDPHRFIHNPHNT 194 TVPIG P N+ +Y+LD MR V G GE+ +AG LARGY RF+ +P + Sbjct: 5089 TVPIGTPAWNSRLYVLDRRMRPVPVGVAGELYLAGVQLARGYQAAPALTAGRFVADPFD- 5147 Query: 195 HPNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 A++YRTGD G + Y RAD QVKI G R++L +++ A+ +P V V L Sbjct: 5148 --RGARMYRTGDIVRRRADGSLEYLERADFQVKIGGFRIELGDIESALLALPGVRAAVAL 5205 Query: 372 CYGVESSNPEILAFVTIN 425 ++ ++A+ ++ Sbjct: 5206 ARTDGAAGARLVAYAAVD 5223 Score = 27.9 bits (59), Expect(2) = 2e-16 Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Frame = +3 Query: 444 AKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 A + AEL L YM+P V+ + +P+ NGKV Sbjct: 5258 AAELRAELRERLPGYMVPAAVMALPALPLTGNGKV 5292 >UniRef50_Q47NR9 Cluster: Non-ribosomal peptide synthase:Amino acid adenylation; n=1; Thermobifida fusca YX|Rep: Non-ribosomal peptide synthase:Amino acid adenylation - Thermobifida fusca (strain YX) Length = 3629 Score = 100 bits (240), Expect = 2e-20 Identities = 61/178 (34%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V IGVP++N VY+LD +R V G GE+ +AG +A GY D RF+ +P+ Sbjct: 2284 VTIGVPMANTRVYVLDAGLRLVPPGVAGELYIAGEGVAWGYHGRFDLTAQRFVADPYG-- 2341 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +++YRTGD G + + GRAD QVKIRG RV+L E++ A++ I + VV+ Sbjct: 2342 PPGSRMYRTGDVVRWRSDGRLDFLGRADFQVKIRGFRVELGEIETALARIDGISQAVVVA 2401 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ ++A++ A I +L + L YM+P + ++ P+ NGK+ Sbjct: 2402 RNDSGNHQRLVAYLVPAGAAAPGTAEIREKLAAVLPAYMVPSAFVVVDEFPLTANGKI 2459 Score = 99.5 bits (237), Expect = 4e-20 Identities = 60/178 (33%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 V IGVP++N VY+LD +R V G GE+ +AG +A GY D RF+ +P+ Sbjct: 3330 VTIGVPMANTRVYVLDAGLRLVPPGVAGELYIAGEGVAWGYHGRFDLTAQRFVADPYG-- 3387 Query: 198 PNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P +++YRTGD G + + GRAD QVKIRG RV+L E++ A++ I + VV+ Sbjct: 3388 PPGSRMYRTGDVVRWRSDGRLDFLGRADFQVKIRGFRVELGEIETALARIDGISQAVVVA 3447 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 ++ ++ +V E ++ + + L +L YM+P + ++ P+ NGK+ Sbjct: 3448 RNDSGNHQRLVGYVV--AERLVTPRELRTALAETLPAYMVPSAFVVVDEFPLTANGKI 3503 Score = 97.1 bits (231), Expect = 2e-19 Identities = 57/179 (31%), Positives = 95/179 (53%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDP--HRFIHNPHNT 194 T +G P+ V +LD+ ++ V G GE+ +AG +ARGY+ D RF+ +P+ Sbjct: 767 TPTVGRPVPGVAVRILDDALQPVPVGVAGELYLAGVQVARGYLGRPDQTADRFVADPYG- 825 Query: 195 HPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P +++YRTGD G + Y GR D+Q+++RG RV+++E++ T P V C V Sbjct: 826 -PPGSRMYRTGDRVRQRADGQLEYLGRVDTQLQVRGFRVEVEEIEAVAETHPAVARCAVA 884 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 + S + + A V ++ ++ + A L L D M+P V+ +PV NGK+ Sbjct: 885 AHTAASGSVRLSAHVVLHQGVTLTPDQLRAHLAEHLPDAMVPAAVVFTSDLPVTPNGKL 943 >UniRef50_Q5IW58 Cluster: Phosphinothricin tripeptide synthetase II; n=2; Streptomyces viridochromogenes|Rep: Phosphinothricin tripeptide synthetase II - Streptomyces viridochromogenes Length = 1086 Score = 100 bits (240), Expect = 2e-20 Identities = 63/178 (35%), Positives = 97/178 (54%), Gaps = 5/178 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 P+G P++ V++LD+ +R V G GE+ + G LARGY+ D RF+ +P T P Sbjct: 810 PLGRPVAGYTVHVLDDTLRPVPFGRQGELFLGGVGLARGYLDQPDVTADRFLPDPSGTEP 869 Query: 201 NFAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A+LYRTGD G + + GR D QVK+RG R++L E++ + P V VVL Sbjct: 870 G-ARLYRTGDVVRWGADGELEFLGRTDHQVKLRGFRIELGEIETRLEDHPGVRTAVVLVR 928 Query: 378 GVESSNPEILAFVTINP-EARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 G E S+ + + P E R +A + L L YM+P++ + ++ +P NGK+ Sbjct: 929 G-EGSDRRLAGYAVRAPGEERPTAAGLRQWLRDRLPGYMVPELFLVLDALPTSPNGKL 985 >UniRef50_Q5DIV7 Cluster: PvdI; n=5; Pseudomonas aeruginosa|Rep: PvdI - Pseudomonas aeruginosa Length = 5155 Score = 100 bits (240), Expect = 2e-20 Identities = 66/178 (37%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG PI+N Y+LD N+ V G GE+ +AG LARGY + G RF+ +P Sbjct: 3356 VPIGRPIANLACYILDGNLEPVPVGVLGELYLAGQGLARGYHQRPGLTAERFVASPFVAG 3415 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD GVI YAGR D QVK+RG R++L E++ + P V VL Sbjct: 3416 ---ERMYRTGDLARYRADGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHPWVREAAVLA 3472 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +++ +V + E+ + + A L +SL +YM+P Q + +E +P+ NGK+ Sbjct: 3473 V----DGKQLVGYVVLESESGDWREALAAHLAASLPEYMVPAQWLALERMPLSPNGKL 3526 Score = 99.5 bits (237), Expect = 4e-20 Identities = 66/178 (37%), Positives = 97/178 (54%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG PI+N Y+LD N+ V G GE+ +AG LARGY + G RF+ +P Sbjct: 829 VPIGRPIANLACYILDGNLEPVPVGVLGELYLAGQGLARGYHQRPGLTAERFVASPFVAG 888 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 ++YRTGD GVI YAGR D QVK+RG R++L E++ + P V VL Sbjct: 889 ---ERMYRTGDLARYRADGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHPRVREAAVLA 945 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 +++ +V + E + + A L +SL +YM+P Q + +E +P+ NGK+ Sbjct: 946 V----DGRQLVGYVVLESEGGDWREALAAHLATSLPEYMVPAQWLALERMPLSPNGKL 999 Score = 81.0 bits (191), Expect = 2e-14 Identities = 58/187 (31%), Positives = 97/187 (51%), Gaps = 13/187 (6%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 +PIG + N Y+LD + + G GE+ + G +ARGY+ RF+ +P Sbjct: 4859 MPIGTLLGNRSGYILDGQLNLLPVGVAGELYLGGEGVARGYLERPALTAERFVPDPFGA- 4917 Query: 198 PNFAKLYRTGDF--GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 P ++LYR+GD G D GV+ Y GR D QVKIRG R++L E++ + P V VV+ Sbjct: 4918 PG-SRLYRSGDLTRGRAD-GVVDYLGRVDHQVKIRGFRIELGEIEARLREHPAVREAVVV 4975 Query: 372 CYGVESSNPEILAFVTI-------NPEARMSAK-NIEAELTSSLTDYMIP-QVIEIETVP 524 + +++ +V +PEA+ + ++ L L +YM+P ++ + +P Sbjct: 4976 AQ-PGAVGQQLVGYVVAQEPAVADSPEAQAECRAQLKTALRERLPEYMVPSHLLFLARMP 5034 Query: 525 VLVNGKV 545 + NGK+ Sbjct: 5035 LTPNGKL 5041 Score = 68.1 bits (159), Expect = 1e-10 Identities = 54/180 (30%), Positives = 88/180 (48%), Gaps = 8/180 (4%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTHPN 203 IG + +LD ++ G GE+ + G LARGY+ G+ RF+ +P + Sbjct: 2306 IGRALGARRACILDAALQPCAPGMIGELYIGGQCLARGYLGRPGQTAERFVADPFSGSGE 2365 Query: 204 FAKLYRTGDFGILD-KGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LYRTGD G + Y GRAD Q+KIRG R+++ E++ + P V V+ Sbjct: 2366 --RLYRTGDLARYRVDGQVEYLGRADQQIKIRGFRIEIGEIESQLLAHPYVAEAAVVAQ- 2422 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAE----LTSSLTDYMIPQVIEI-ETVPVLVNGKV 545 + +LA + +A M +++ AE L L YM P ++ ++P+ NGK+ Sbjct: 2423 -DGVGGPLLAAYLVGRDA-MRGEDLLAELRTWLAGRLPAYMQPTAWQVLSSLPLNANGKL 2480 >UniRef50_Q4H1C8 Cluster: Non-ribosomal peptide synthetase B; n=1; Actinoplanes friuliensis|Rep: Non-ribosomal peptide synthetase B - Actinoplanes friuliensis Length = 3143 Score = 100 bits (240), Expect = 2e-20 Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNTH 197 VPIG P+ N +Y+LD ++ V G GE+ + G LARGYV G RF+ +P+ Sbjct: 745 VPIGRPLPGNRLYVLDPALQPVPAGATGELYIGGTGLARGYVNRPGLTGQRFVADPY-AG 803 Query: 198 PNFAKLYRTGDFGIL-DKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P A++YR+GD L G + Y GR D QVKIRG+RV+ E++ +++ V C V+ Sbjct: 804 PG-ARMYRSGDLARLRADGNLEYLGRIDDQVKIRGYRVEPGEIEAVLASADQVARCAVVV 862 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 + ++A+V + + + + A L + L YM+P ++ ++ +P NGKV Sbjct: 863 REDRPGDQRLVAYV-VAADGTVDPSALTAHLAARLPAYMVPSAIVGLDELPWTANGKV 919 Score = 94.3 bits (224), Expect = 2e-18 Identities = 60/182 (32%), Positives = 96/182 (52%), Gaps = 7/182 (3%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVR--GKDPHRFIHNPHNT 194 T PIG P+ N V++LD ++ V G PGE+ V G LARGY+ G+ RF+ +P Sbjct: 2363 TAPIGRPLWNATVFVLDARLQPVPLGAPGELYVGGAQLARGYLNRPGRTAERFVASPFGA 2422 Query: 195 HPNFAKLYRTGDFGILDK-GVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 + +LYRTGD + G + + GR D QVKI G RV+ EV+ ++ P V VV+ Sbjct: 2423 PGD--RLYRTGDLVRWTRDGELQFLGRGDHQVKIGGFRVEPGEVEGVLAAHPGVTTAVVV 2480 Query: 372 CYGVESSNPEILAFVTINPEARM---SAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNG 539 ++A+ +P+ + + + A L L Y++P V+ ++ +P+ NG Sbjct: 2481 PRDDLPGGTRLVAYAVPDPQHDLGPDGGRRLRAHLEEHLPSYLVPAAVVLLDVLPLTPNG 2540 Query: 540 KV 545 K+ Sbjct: 2541 KL 2542 >UniRef50_A5YBV1 Cluster: Fusaricidin synthetase; n=1; Paenibacillus polymyxa|Rep: Fusaricidin synthetase - Paenibacillus polymyxa (Bacillus polymyxa) Length = 2564 Score = 100 bits (240), Expect = 2e-20 Identities = 64/176 (36%), Positives = 92/176 (52%), Gaps = 4/176 (2%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHPN 203 IG I Y+LDE R G PGE+ +AG LARGY+ D +F+ +P+ Sbjct: 776 IGRTIPTLSAYILDEQRRLQPVGVPGELYIAGDGLARGYLNRPDLTSEKFVEHPYRVGE- 834 Query: 204 FAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCYG 380 +LYRTGD L G I Y GR D QVKIRG+R++L EV+ + P V +VL Sbjct: 835 --RLYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKAPSVRETIVLARE 892 Query: 381 VESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E + A+ + + +S + A+L + L YMIP + +E +P+ NGK+ Sbjct: 893 DEQGQKLLCAYYVASSD--LSPGELRAQLAAELPAYMIPSYFVPLEQMPLTPNGKL 946 Score = 89.0 bits (211), Expect = 6e-17 Identities = 57/178 (32%), Positives = 96/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI N+ Y+++ +++ G GE+ V G +ARGY+ D +F+ +P Sbjct: 1808 VPIGRPIRNSTAYVVNGSLQLQPIGAWGELIVGGEGVARGYLNRPDLTAEKFVPSPVK-- 1865 Query: 198 PNFAKLYRTGDF-GILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 + YRTGD L G + + GR D QVKIRG+R++L E++ ++ + V + VV+ Sbjct: 1866 -DGEPCYRTGDLVRWLPDGNLEFKGRIDEQVKIRGYRIELPEIEAQLAKVESVIDAVVVV 1924 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQ-VIEIETVPVLVNGKV 545 E ++ A+ + ++A + L+ L YMIP I+++ +P+ NGKV Sbjct: 1925 RADELGEKQLCAYYV--ADRTLTAGEVRLSLSQVLPGYMIPSYFIQMDRMPLTSNGKV 1980 >UniRef50_Q8YTR9 Cluster: Peptide synthetase; n=2; Nostocaceae|Rep: Peptide synthetase - Anabaena sp. (strain PCC 7120) Length = 2617 Score = 100 bits (239), Expect = 3e-20 Identities = 64/178 (35%), Positives = 97/178 (54%), Gaps = 6/178 (3%) Frame = +3 Query: 30 IGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGY-VRGK-DPHRFIHNP--HNTH 197 IG PI+N VY+LD+N++ V G PGE+ ++G LARGY R K RFI ++ Sbjct: 1840 IGQPIANTQVYILDQNLQPVPVGIPGEIYLSGAGLARGYWKRPKLTDERFIKQSTVNSQQ 1899 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 LY+TGD L G I Y GR D QVK+RG R++L E++ + P + V + Sbjct: 1900 STVNTLYKTGDRARYLPDGNIEYLGRFDHQVKLRGFRIELGEIEALLHQHPELTQAVAIV 1959 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V P++ + A + L + L YM+P + +ET+P+ NGKV Sbjct: 1960 RNDTPEHSRLVAYVV--PKSHIEAAELRQFLAAKLPAYMLPTAFVILETLPLTANGKV 2015 Score = 97.1 bits (231), Expect = 2e-19 Identities = 60/181 (33%), Positives = 98/181 (54%), Gaps = 7/181 (3%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNP---H 188 V IG PI+N Y+LDE+++ V G PGE+ + G +A+GY + D RF++ + Sbjct: 794 VTIGHPIANTQFYVLDEHLQPVPIGVPGELYIGGAGVAKGYWQRPDLTAERFLNQQSTVN 853 Query: 189 NTHPNFAKLYRTGD-FGILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCV 365 + LY+TGD L G + Y GR D QVKIRG R++L E++ ++ P + V Sbjct: 854 SQQSTVNTLYKTGDRVRYLPDGKLEYLGRLDYQVKIRGFRIELGEIEAVLAQHPQISQAV 913 Query: 366 VLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGK 542 V E ++A++ N + + + +++ L + L YMIP V + + +P+ NGK Sbjct: 914 VSVQEDEPGEQRLVAYIVPNSQ-DVGSNDLQQFLANKLPKYMIPGVFVTLTALPLTPNGK 972 Query: 543 V 545 V Sbjct: 973 V 973 >UniRef50_Q4ZVI3 Cluster: Amino acid adenylation; n=3; Pseudomonas|Rep: Amino acid adenylation - Pseudomonas syringae pv. syringae (strain B728a) Length = 3021 Score = 100 bits (239), Expect = 3e-20 Identities = 64/177 (36%), Positives = 98/177 (55%), Gaps = 4/177 (2%) Frame = +3 Query: 27 PIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTHP 200 PIG PI+N +Y+LD ++ V G GE+ +AG LARGY+ D RF+ +P N Sbjct: 1423 PIGRPIANARLYVLDGDLNPVPVGVAGELYIAGACLARGYLNRPDLSAERFLPDPFNPQS 1482 Query: 201 NFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 A++YR+GD G + Y GR D QVK+RG RV+L E+D + P V VVL Sbjct: 1483 G-ARMYRSGDLARFAADGNVHYLGRIDQQVKLRGFRVELGEIDSLLHQQPGVREAVVLLR 1541 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVNGKV 545 + ++A+V + P +A+ + AEL L ++M+P + + +P+ NGK+ Sbjct: 1542 EDVPGDKRLVAYV-VGP---ATAETLRAELHRHLPEHMVPTAWVALAQLPLTRNGKL 1594 Score = 94.3 bits (224), Expect = 2e-18 Identities = 59/183 (32%), Positives = 97/183 (53%), Gaps = 4/183 (2%) Frame = +3 Query: 9 HIFLTVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHN 182 H+ +PIG ++N +YLLD V +G GE+ + G +ARGY+ + RFI + Sbjct: 346 HVDAVLPIGRALANTRIYLLDAAGDRVPQGVTGELYIGGAGVARGYLNLPELTRERFIDS 405 Query: 183 PHNTHPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDN 359 P +LYRTGD G + + GR DSQ K+RG R++L E++ ++ + V + Sbjct: 406 PFVAGD---RLYRTGDLARYRADGHLEFLGRNDSQAKLRGLRLELGEIEARLAEVAGVRD 462 Query: 360 CVVLCYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQV-IEIETVPVLVN 536 VV+ + P ++A+ A ++ K + L SL DYMIP + ++ +P+ N Sbjct: 463 NVVVLREDGAGVPRLIAYFREQTGAALTPKGLRQHLQLSLPDYMIPAAFVRMDALPLTAN 522 Query: 537 GKV 545 GK+ Sbjct: 523 GKL 525 Score = 84.2 bits (199), Expect = 2e-15 Identities = 55/178 (30%), Positives = 90/178 (50%), Gaps = 3/178 (1%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHP 200 ++P G + + Y+LD+ ++ G++ + G LA+GY R + HP Sbjct: 2483 SIPYGKALDHQRFYVLDDALQVRPTWVAGQLYIGGIGLAKGYWRDE---ALSAGSFFAHP 2539 Query: 201 -NFAKLYRTGDFGI-LDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 +LYRTGD G L G I + GR D+QVK++GHR++L E++ A++ P V + VV Sbjct: 2540 LTGERLYRTGDLGRWLPDGNIEFLGREDTQVKVQGHRIELGEIEAALNRHPGVQSAVVRV 2599 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIPQVIE-IETVPVLVNGKV 545 G E+ + LA + + + A + L L YM+P ++ P+ NGKV Sbjct: 2600 LG-EALGEKRLAGYVLKADPSLQASDFVQYLADKLPAYMLPTSFTFVQEWPLSANGKV 2656 >UniRef50_Q311J0 Cluster: Amino acid adenylation; n=2; Bacteria|Rep: Amino acid adenylation - Desulfovibrio desulfuricans (strain G20) Length = 3252 Score = 100 bits (239), Expect = 3e-20 Identities = 62/179 (34%), Positives = 94/179 (52%), Gaps = 4/179 (2%) Frame = +3 Query: 21 TVPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRG--KDPHRFIHNPHNT 194 TVP G P+ N + +LDE + GE+ + G LA GY+ K +FI +P Sbjct: 1901 TVPYGTPLPNQKLMVLDEQLEIAPAWVTGELHIGGKGLALGYLNDPEKTAAQFIRHPRTG 1960 Query: 195 HPNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVL 371 +LY+TGD G L G I + GR D+QVKIRGHRV+ E++H + P V V+ Sbjct: 1961 E----RLYKTGDLGRYLPDGTIEFIGRKDAQVKIRGHRVEPGEIEHCLLRHPAVHKAAVI 2016 Query: 372 CYGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 G ++ P LA + + + A L S+L ++M+P Q+I + +P+ NGK+ Sbjct: 2017 AVG-DAGKPRSLAAFVVT----TAHDELRAFLRSNLPEHMVPSQIIAVPALPLTENGKL 2070 Score = 99.5 bits (237), Expect = 4e-20 Identities = 57/177 (32%), Positives = 96/177 (54%), Gaps = 3/177 (1%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKDPHRFIHNPHNTHPN 203 +P G P++N +++L+ + E PG++ + G LA GY+ D H+ THP Sbjct: 2956 IPYGTPMTNQQMHVLNAALEPCPEWVPGQLYIGGSGLAEGYLN--DRHK-TQAAFITHPA 3012 Query: 204 FA-KLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLCY 377 +LY+TGD + +G I + GR D QVKIRGHRV+L E+++A++ P + ++ + Sbjct: 3013 TGERLYKTGDLARVRPEGFIEFLGREDQQVKIRGHRVELGEIENALTLHPQIKEALITLH 3072 Query: 378 GVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 G S +LA++T+ + +A+ + L L +MIP + PV NGK+ Sbjct: 3073 GESISGKRLLAYLTVQQQP-PAAEELRDHLAQVLPRFMIPDHFFFLTEFPVTANGKI 3128 >UniRef50_Q9FB27 Cluster: Peptide synthetase NRPS9-8; n=2; Actinomycetales|Rep: Peptide synthetase NRPS9-8 - Streptomyces verticillus Length = 2162 Score = 100 bits (239), Expect = 3e-20 Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 4/178 (2%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYV-RGKDPHR-FIHNPHNTH 197 +PIG P++ +V+ D R V G GE+ + G +ARGY+ R +D F +P T Sbjct: 1868 LPIGRPVAGTWVHPRDHRGRTVPLGVAGELSIGGAGVARGYLGRPRDTAAAFRPDPEATA 1927 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P + Y TGD G L G + + GRAD QVKIRG RV+L E++ + T P + +V+ Sbjct: 1928 PG-GRAYATGDLGRYLPDGNLEFLGRADHQVKIRGFRVELGEIEAVLDTHPELQRTIVMA 1986 Query: 375 YGVESSNPEILAFVTINPEARMSAKNIEAELTSSLTDYMIP-QVIEIETVPVLVNGKV 545 G + ++A+V P R +I+ + L YM+P VI ++ VP+ GKV Sbjct: 1987 RGDHPGDQVLVAYVLPAPGRRPEPADIQGYVRDRLPRYMVPTAVIVLDAVPLTAAGKV 2044 Score = 79.4 bits (187), Expect = 5e-14 Identities = 61/187 (32%), Positives = 97/187 (51%), Gaps = 13/187 (6%) Frame = +3 Query: 24 VPIGVPISNNYVYLLDENMRCVREGEPGEVCVAGFNLARGYVRGKD--PHRFIHNPHNTH 197 VPIG PI+N V+LLD+ R V +G GE+ + G +A GY+ + RF+ P + Sbjct: 796 VPIGRPIANTTVHLLDQRRRPVPDGVVGELWIGGAGVADGYLGRPELTGERFL--PSDYP 853 Query: 198 PNFAKLYRTGDFG-ILDKGVILYAGRADSQVKIRGHRVDLQEVDHAVSTIPCVDNCVVLC 374 P+ ++YRTGD G + Y GR D+QVKIRG RV+ E + +++ P V VV+ Sbjct: 854 PDGGRVYRTGDLARRRADGTLEYLGRTDAQVKIRGVRVEPAETEAVLASHPGVGQAVVVA 913 Query: 375 YGVES---SNP---EILAFVTINPEARMSA---KNIEAELTSSLTDYMIPQV-IEIETVP 524 E S+P E+ + P A + + A L ++ +P V + ++ +P Sbjct: 914 RLDEDPGRSSPLAGELTLTGYVVPARGAQAPPHEELIAYCRERLPEHFVPAVLVTLDALP 973 Query: 525 VLVNGKV 545 V +GK+ Sbjct: 974 VTGHGKI 980 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 599,378,977 Number of Sequences: 1657284 Number of extensions: 13030065 Number of successful extensions: 38362 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 34080 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 36160 length of database: 575,637,011 effective HSP length: 96 effective length of database: 416,537,747 effective search space used: 35405708495 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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