Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0007_M09
(649 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine hydroxym... 292 6e-79
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 292 6e-79
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 292 6e-79
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 292 6e-79
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 292 6e-79
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 292 6e-79
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 292 6e-79
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 292 6e-79
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 292 6e-79
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 292 6e-79
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 268 1e-71
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 268 1e-71
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 268 1e-71
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 268 1e-71
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 268 1e-71
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 268 1e-71
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 268 1e-71
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 240 3e-63
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 208 1e-53
Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein. 60 7e-09
Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine hydroxym... 52 2e-06
AK055053-1|BAB70847.1| 135|Homo sapiens protein. 37 0.054
>Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 347
Score = 292 bits (717), Expect = 6e-79
Identities = 134/190 (70%), Positives = 158/190 (83%)
Frame = +3
Query: 75 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 254
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 255 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGR 434
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGR
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGR 137
Query: 435 IMGLDLPDGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRV 614
IMGLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++
Sbjct: 138 IMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKL 197
Query: 615 IIAGMSCYSR 644
IIAG SCYSR
Sbjct: 198 IIAGTSCYSR 207
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 292 bits (717), Expect = 6e-79
Identities = 134/190 (70%), Positives = 158/190 (83%)
Frame = +3
Query: 75 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 254
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 255 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGR 434
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGR
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGR 137
Query: 435 IMGLDLPDGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRV 614
IMGLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++
Sbjct: 138 IMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKL 197
Query: 615 IIAGMSCYSR 644
IIAG SCYSR
Sbjct: 198 IIAGTSCYSR 207
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 292 bits (717), Expect = 6e-79
Identities = 134/190 (70%), Positives = 158/190 (83%)
Frame = +3
Query: 75 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 254
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 255 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGR 434
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGR
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGR 137
Query: 435 IMGLDLPDGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRV 614
IMGLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++
Sbjct: 138 IMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKL 197
Query: 615 IIAGMSCYSR 644
IIAG SCYSR
Sbjct: 198 IIAGTSCYSR 207
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 292 bits (717), Expect = 6e-79
Identities = 134/190 (70%), Positives = 158/190 (83%)
Frame = +3
Query: 75 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 254
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 255 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGR 434
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGR
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGR 137
Query: 435 IMGLDLPDGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRV 614
IMGLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++
Sbjct: 138 IMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKL 197
Query: 615 IIAGMSCYSR 644
IIAG SCYSR
Sbjct: 198 IIAGTSCYSR 207
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 292 bits (717), Expect = 6e-79
Identities = 134/190 (70%), Positives = 158/190 (83%)
Frame = +3
Query: 75 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 254
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 255 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGR 434
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGR
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGR 137
Query: 435 IMGLDLPDGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRV 614
IMGLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++
Sbjct: 138 IMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKL 197
Query: 615 IIAGMSCYSR 644
IIAG SCYSR
Sbjct: 198 IIAGTSCYSR 207
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 292 bits (717), Expect = 6e-79
Identities = 134/190 (70%), Positives = 158/190 (83%)
Frame = +3
Query: 75 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 254
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 255 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGR 434
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGR
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGR 137
Query: 435 IMGLDLPDGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRV 614
IMGLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++
Sbjct: 138 IMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKL 197
Query: 615 IIAGMSCYSR 644
IIAG SCYSR
Sbjct: 198 IIAGTSCYSR 207
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 292 bits (717), Expect = 6e-79
Identities = 134/190 (70%), Positives = 158/190 (83%)
Frame = +3
Query: 75 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 254
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 255 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGR 434
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGR
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGR 137
Query: 435 IMGLDLPDGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRV 614
IMGLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++
Sbjct: 138 IMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKL 197
Query: 615 IIAGMSCYSR 644
IIAG SCYSR
Sbjct: 198 IIAGTSCYSR 207
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 292 bits (717), Expect = 6e-79
Identities = 134/190 (70%), Positives = 158/190 (83%)
Frame = +3
Query: 75 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 254
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 255 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGR 434
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGR
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGR 137
Query: 435 IMGLDLPDGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRV 614
IMGLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++
Sbjct: 138 IMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKL 197
Query: 615 IIAGMSCYSR 644
IIAG SCYSR
Sbjct: 198 IIAGTSCYSR 207
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 292 bits (717), Expect = 6e-79
Identities = 134/190 (70%), Positives = 158/190 (83%)
Frame = +3
Query: 75 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 254
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 255 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGR 434
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGR
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGR 137
Query: 435 IMGLDLPDGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRV 614
IMGLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++
Sbjct: 138 IMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKL 197
Query: 615 IIAGMSCYSR 644
IIAG SCYSR
Sbjct: 198 IIAGTSCYSR 207
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 292 bits (717), Expect = 6e-79
Identities = 134/190 (70%), Positives = 158/190 (83%)
Frame = +3
Query: 75 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 254
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 255 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGR 434
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHGR
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGR 137
Query: 435 IMGLDLPDGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRV 614
IMGLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P TG I+YD+L E A+LF P++
Sbjct: 138 IMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKL 197
Query: 615 IIAGMSCYSR 644
IIAG SCYSR
Sbjct: 198 IIAGTSCYSR 207
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 268 bits (657), Expect = 1e-71
Identities = 121/183 (66%), Positives = 152/183 (83%)
Frame = +3
Query: 96 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 275
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 27 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 86
Query: 276 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLP 455
G E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 87 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 146
Query: 456 DGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSC 635
DGGHLTHG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S
Sbjct: 147 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 206
Query: 636 YSR 644
Y+R
Sbjct: 207 YAR 209
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 268 bits (657), Expect = 1e-71
Identities = 121/183 (66%), Positives = 152/183 (83%)
Frame = +3
Query: 96 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 275
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 18 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 77
Query: 276 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLP 455
G E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 78 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 137
Query: 456 DGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSC 635
DGGHLTHG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S
Sbjct: 138 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 197
Query: 636 YSR 644
Y+R
Sbjct: 198 YAR 200
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 268 bits (657), Expect = 1e-71
Identities = 121/183 (66%), Positives = 152/183 (83%)
Frame = +3
Query: 96 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 275
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 276 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLP 455
G E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 456 DGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSC 635
DGGHLTHG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 636 YSR 644
Y+R
Sbjct: 228 YAR 230
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 268 bits (657), Expect = 1e-71
Identities = 121/183 (66%), Positives = 152/183 (83%)
Frame = +3
Query: 96 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 275
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 276 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLP 455
G E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 456 DGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSC 635
DGGHLTHG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 636 YSR 644
Y+R
Sbjct: 228 YAR 230
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 268 bits (657), Expect = 1e-71
Identities = 121/183 (66%), Positives = 152/183 (83%)
Frame = +3
Query: 96 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 275
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 276 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLP 455
G E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 456 DGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSC 635
DGGHLTHG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 636 YSR 644
Y+R
Sbjct: 228 YAR 230
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 268 bits (657), Expect = 1e-71
Identities = 121/183 (66%), Positives = 152/183 (83%)
Frame = +3
Query: 96 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 275
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 276 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLP 455
G E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 456 DGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSC 635
DGGHLTHG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 636 YSR 644
Y+R
Sbjct: 228 YAR 230
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 268 bits (657), Expect = 1e-71
Identities = 121/183 (66%), Positives = 152/183 (83%)
Frame = +3
Query: 96 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 275
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 276 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLP 455
G E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 456 DGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSC 635
DGGHLTHG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 636 YSR 644
Y+R
Sbjct: 228 YAR 230
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 240 bits (588), Expect = 3e-63
Identities = 114/183 (62%), Positives = 143/183 (78%)
Frame = +3
Query: 96 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 275
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 276 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLP 455
G E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 456 DGGHLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSC 635
DGGHLTHG+ + K+ISATSIFFESMPYK++ LA TA+LF+PR+IIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLN----------LALTARLFRPRLIIAGTSA 217
Query: 636 YSR 644
Y+R
Sbjct: 218 YAR 220
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 208 bits (509), Expect = 1e-53
Identities = 101/180 (56%), Positives = 130/180 (72%), Gaps = 6/180 (3%)
Frame = +3
Query: 123 FNLITKEKKRQQAGLEMIASE--NFTSVPVLQCLSSCLHNKYSEGMPY----QRYYGGNE 284
F L T + R + G + A + +L+C S C + + + QRYYGG E
Sbjct: 27 FGLSTATQPRLRLGKQTGAGQARRACRTVILRCGSCCRGRRTGSVVAWSSLPQRYYGGAE 86
Query: 285 FIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGRIMGLDLPDGG 464
+DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 87 VVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGG 146
Query: 465 HLTHGFFTANKKISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSR 644
HLTHG+ + K+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R
Sbjct: 147 HLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYAR 206
>Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein.
Length = 129
Score = 60.1 bits (139), Expect = 7e-09
Identities = 24/37 (64%), Positives = 30/37 (81%)
Frame = +3
Query: 264 RYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 374
RYYGG EFIDE+E L Q R+L+ YKL+P+ WGV+V P
Sbjct: 65 RYYGGTEFIDELETLCQKRALQAYKLDPQCWGVDVHP 101
>Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 310
Score = 52.0 bits (119), Expect = 2e-06
Identities = 22/34 (64%), Positives = 28/34 (82%)
Frame = +3
Query: 543 VDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSR 644
V+P TG I+YD+L E A+LF P++IIAG SCYSR
Sbjct: 1 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSR 34
>AK055053-1|BAB70847.1| 135|Homo sapiens protein.
Length = 135
Score = 37.1 bits (82), Expect = 0.054
Identities = 16/30 (53%), Positives = 24/30 (80%)
Frame = +3
Query: 96 NLWETDPELFNLITKEKKRQQAGLEMIASE 185
+L ++DPE++ L+ +EK RQ GLE+IASE
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASE 77
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 96,790,738
Number of Sequences: 237096
Number of extensions: 2116470
Number of successful extensions: 4298
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 4159
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4297
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7197658880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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