Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0006_C11
(576 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 202 7e-52
Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine hydroxym... 200 2e-51
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 200 2e-51
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 200 2e-51
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 200 2e-51
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 200 2e-51
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 200 2e-51
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 200 2e-51
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 200 2e-51
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 200 2e-51
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 200 2e-51
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 200 2e-51
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 200 2e-51
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 200 2e-51
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 200 2e-51
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 199 5e-51
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 141 2e-33
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 141 2e-33
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 110 4e-24
Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine hydroxym... 91 2e-18
Y14489-1|CAB54842.1| 92|Homo sapiens cytosolic serine hydroxym... 53 6e-07
BX119957-17|CAM25921.1| 433|Homo sapiens chromosome 6 open read... 29 8.9
BC064397-1|AAH64397.1| 433|Homo sapiens C6orf136 protein protein. 29 8.9
AL732442-10|CAI17760.2| 433|Homo sapiens chromosome 6 open read... 29 8.9
AL662800-21|CAI95540.2| 433|Homo sapiens chromosome 6 open read... 29 8.9
AL662798-7|CAI95541.2| 433|Homo sapiens chromosome 6 open readi... 29 8.9
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 202 bits (493), Expect = 7e-52
Identities = 97/192 (50%), Positives = 131/192 (68%), Gaps = 1/192 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
+G+IF+RKGV++V G++++Y FE +IN AVFP LQGGPHNH +KQA +P
Sbjct: 257 SGLIFYRKGVKAVDPKTGREILYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 316
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F EY QV+KNA+ + + L+ RGY++ +GGTD HL LVDLR GL GA ER+LEL SI
Sbjct: 317 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 376
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSGPKL 539
NKNT PGD+SA+ P G+RLG PALT+R +E D VV++ID+ + I V+ KL
Sbjct: 377 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE-VKSKTAKL 435
Query: 540 ADFNKAIEENSE 575
DF + ++SE
Sbjct: 436 QDFKSFLLKDSE 447
>Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 310
Score = 200 bits (489), Expect = 2e-51
Identities = 96/177 (54%), Positives = 121/177 (68%), Gaps = 1/177 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
AG+IF+RKGV+SV G++++Y+ E IN AVFPGLQGGPHNH +KQA + E
Sbjct: 91 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 150
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F YQ QV+ N + L E L GY I TGG+D HL LVDLRS G G E++LE CSIA
Sbjct: 151 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 210
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSG 530
CNKNT PGD+SAL PSG+RLGTPALT+RGL E D V ++I + +++ I +G
Sbjct: 211 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 267
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 200 bits (489), Expect = 2e-51
Identities = 96/177 (54%), Positives = 121/177 (68%), Gaps = 1/177 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
AG+IF+RKGV+SV G++++Y+ E IN AVFPGLQGGPHNH +KQA + E
Sbjct: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F YQ QV+ N + L E L GY I TGG+D HL LVDLRS G G E++LE CSIA
Sbjct: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSG 530
CNKNT PGD+SAL PSG+RLGTPALT+RGL E D V ++I + +++ I +G
Sbjct: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 440
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 200 bits (489), Expect = 2e-51
Identities = 97/192 (50%), Positives = 130/192 (67%), Gaps = 1/192 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
+G+IF+RKGV++V G+++ Y FE +IN AVFP LQGGPHNH +KQA +P
Sbjct: 266 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 325
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F EY QV+KNA+ + + L+ RGY++ +GGTD HL LVDLR GL GA ER+LEL SI
Sbjct: 326 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 385
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSGPKL 539
NKNT PGD+SA+ P G+RLG PALT+R +E D VV++ID+ + I V+ KL
Sbjct: 386 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE-VKSKTAKL 444
Query: 540 ADFNKAIEENSE 575
DF + ++SE
Sbjct: 445 QDFKSFLLKDSE 456
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 200 bits (489), Expect = 2e-51
Identities = 96/177 (54%), Positives = 121/177 (68%), Gaps = 1/177 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
AG+IF+RKGV+SV G++++Y+ E IN AVFPGLQGGPHNH +KQA + E
Sbjct: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F YQ QV+ N + L E L GY I TGG+D HL LVDLRS G G E++LE CSIA
Sbjct: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSG 530
CNKNT PGD+SAL PSG+RLGTPALT+RGL E D V ++I + +++ I +G
Sbjct: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 440
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 200 bits (489), Expect = 2e-51
Identities = 96/177 (54%), Positives = 121/177 (68%), Gaps = 1/177 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
AG+IF+RKGV+SV G++++Y+ E IN AVFPGLQGGPHNH +KQA + E
Sbjct: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F YQ QV+ N + L E L GY I TGG+D HL LVDLRS G G E++LE CSIA
Sbjct: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSG 530
CNKNT PGD+SAL PSG+RLGTPALT+RGL E D V ++I + +++ I +G
Sbjct: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 440
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 200 bits (489), Expect = 2e-51
Identities = 97/192 (50%), Positives = 130/192 (67%), Gaps = 1/192 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
+G+IF+RKGV++V G+++ Y FE +IN AVFP LQGGPHNH +KQA +P
Sbjct: 287 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 346
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F EY QV+KNA+ + + L+ RGY++ +GGTD HL LVDLR GL GA ER+LEL SI
Sbjct: 347 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 406
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSGPKL 539
NKNT PGD+SA+ P G+RLG PALT+R +E D VV++ID+ + I V+ KL
Sbjct: 407 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE-VKSKTAKL 465
Query: 540 ADFNKAIEENSE 575
DF + ++SE
Sbjct: 466 QDFKSFLLKDSE 477
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 200 bits (489), Expect = 2e-51
Identities = 97/192 (50%), Positives = 130/192 (67%), Gaps = 1/192 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
+G+IF+RKGV++V G+++ Y FE +IN AVFP LQGGPHNH +KQA +P
Sbjct: 263 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 322
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F EY QV+KNA+ + + L+ RGY++ +GGTD HL LVDLR GL GA ER+LEL SI
Sbjct: 323 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 382
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSGPKL 539
NKNT PGD+SA+ P G+RLG PALT+R +E D VV++ID+ + I V+ KL
Sbjct: 383 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE-VKSKTAKL 441
Query: 540 ADFNKAIEENSE 575
DF + ++SE
Sbjct: 442 QDFKSFLLKDSE 453
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 200 bits (489), Expect = 2e-51
Identities = 97/192 (50%), Positives = 130/192 (67%), Gaps = 1/192 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
+G+IF+RKGV++V G+++ Y FE +IN AVFP LQGGPHNH +KQA +P
Sbjct: 287 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 346
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F EY QV+KNA+ + + L+ RGY++ +GGTD HL LVDLR GL GA ER+LEL SI
Sbjct: 347 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 406
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSGPKL 539
NKNT PGD+SA+ P G+RLG PALT+R +E D VV++ID+ + I V+ KL
Sbjct: 407 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE-VKSKTAKL 465
Query: 540 ADFNKAIEENSE 575
DF + ++SE
Sbjct: 466 QDFKSFLLKDSE 477
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 200 bits (489), Expect = 2e-51
Identities = 96/177 (54%), Positives = 121/177 (68%), Gaps = 1/177 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
AG+IF+RKGV+SV G++++Y+ E IN AVFPGLQGGPHNH +KQA + E
Sbjct: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F YQ QV+ N + L E L GY I TGG+D HL LVDLRS G G E++LE CSIA
Sbjct: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSG 530
CNKNT PGD+SAL PSG+RLGTPALT+RGL E D V ++I + +++ I +G
Sbjct: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 440
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 200 bits (489), Expect = 2e-51
Identities = 97/192 (50%), Positives = 130/192 (67%), Gaps = 1/192 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
+G+IF+RKGV++V G+++ Y FE +IN AVFP LQGGPHNH +KQA +P
Sbjct: 277 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 336
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F EY QV+KNA+ + + L+ RGY++ +GGTD HL LVDLR GL GA ER+LEL SI
Sbjct: 337 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 396
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSGPKL 539
NKNT PGD+SA+ P G+RLG PALT+R +E D VV++ID+ + I V+ KL
Sbjct: 397 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE-VKSKTAKL 455
Query: 540 ADFNKAIEENSE 575
DF + ++SE
Sbjct: 456 QDFKSFLLKDSE 467
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 200 bits (489), Expect = 2e-51
Identities = 97/192 (50%), Positives = 130/192 (67%), Gaps = 1/192 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
+G+IF+RKGV++V G+++ Y FE +IN AVFP LQGGPHNH +KQA +P
Sbjct: 287 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 346
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F EY QV+KNA+ + + L+ RGY++ +GGTD HL LVDLR GL GA ER+LEL SI
Sbjct: 347 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 406
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSGPKL 539
NKNT PGD+SA+ P G+RLG PALT+R +E D VV++ID+ + I V+ KL
Sbjct: 407 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE-VKSKTAKL 465
Query: 540 ADFNKAIEENSE 575
DF + ++SE
Sbjct: 466 QDFKSFLLKDSE 477
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 200 bits (489), Expect = 2e-51
Identities = 97/192 (50%), Positives = 130/192 (67%), Gaps = 1/192 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
+G+IF+RKGV++V G+++ Y FE +IN AVFP LQGGPHNH +KQA +P
Sbjct: 287 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 346
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F EY QV+KNA+ + + L+ RGY++ +GGTD HL LVDLR GL GA ER+LEL SI
Sbjct: 347 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 406
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSGPKL 539
NKNT PGD+SA+ P G+RLG PALT+R +E D VV++ID+ + I V+ KL
Sbjct: 407 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE-VKSKTAKL 465
Query: 540 ADFNKAIEENSE 575
DF + ++SE
Sbjct: 466 QDFKSFLLKDSE 477
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 200 bits (489), Expect = 2e-51
Identities = 96/177 (54%), Positives = 121/177 (68%), Gaps = 1/177 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
AG+IF+RKGV+SV G++++Y+ E IN AVFPGLQGGPHNH +KQA + E
Sbjct: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F YQ QV+ N + L E L GY I TGG+D HL LVDLRS G G E++LE CSIA
Sbjct: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSG 530
CNKNT PGD+SAL PSG+RLGTPALT+RGL E D V ++I + +++ I +G
Sbjct: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 440
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 200 bits (489), Expect = 2e-51
Identities = 96/177 (54%), Positives = 121/177 (68%), Gaps = 1/177 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
AG+IF+RKGV+SV G++++Y+ E IN AVFPGLQGGPHNH +KQA + E
Sbjct: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAEVAVALKQAMTLE 323
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F YQ QV+ N + L E L GY I TGG+D HL LVDLRS G G E++LE CSIA
Sbjct: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSG 530
CNKNT PGD+SAL PSG+RLGTPALT+RGL E D V ++I + +++ I +G
Sbjct: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 440
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 199 bits (486), Expect = 5e-51
Identities = 97/192 (50%), Positives = 129/192 (67%), Gaps = 1/192 (0%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
+G+IF+RKGV++V G+++ Y FE +IN AVFP LQGGPHNH +KQA +P
Sbjct: 287 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 346
Query: 180 FIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGERILELCSIA 359
F EY QV+KNA+ + + L+ RGY++ +GGTD HL LVDLR GL GA ER+LEL SI
Sbjct: 347 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 406
Query: 360 CNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSGPKL 539
NKNT PGD+SA+ P G+RLG PALT+R E D VV++ID+ + I V+ KL
Sbjct: 407 ANKNTCPGDRSAITPGGLRLGAPALTSRQFHEDDFRRVVDFIDEGVNIGLE-VKSKTAKL 465
Query: 540 ADFNKAIEENSE 575
DF + ++SE
Sbjct: 466 QDFKSFLLKDSE 477
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 141 bits (341), Expect = 2e-33
Identities = 68/125 (54%), Positives = 85/125 (68%)
Frame = +3
Query: 156 MKQATSPEFIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGER 335
+KQA + EF YQ QV+ N + L E L GY I TGG+D HL LVDLRS G G E+
Sbjct: 277 LKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEK 336
Query: 336 ILELCSIACNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTI 515
+LE CSIACNKNT PGD+SAL PSG+RLGTPALT+RGL E D V ++I + +++ I
Sbjct: 337 VLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQI 396
Query: 516 VEVSG 530
+G
Sbjct: 397 QSDTG 401
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 141 bits (341), Expect = 2e-33
Identities = 68/125 (54%), Positives = 85/125 (68%)
Frame = +3
Query: 156 MKQATSPEFIEYQKQVIKNAQRLCEGLISRGYAIATGGTDVHLALVDLRSVGLTGAPGER 335
+KQA + EF YQ QV+ N + L E L GY I TGG+D HL LVDLRS G G E+
Sbjct: 277 LKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEK 336
Query: 336 ILELCSIACNKNTVPGDKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTI 515
+LE CSIACNKNT PGD+SAL PSG+RLGTPALT+RGL E D V ++I + +++ I
Sbjct: 337 VLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQI 396
Query: 516 VEVSG 530
+G
Sbjct: 397 QSDTG 401
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 110 bits (264), Expect = 4e-24
Identities = 51/89 (57%), Positives = 64/89 (71%)
Frame = +3
Query: 264 GGTDVHLALVDLRSVGLTGAPGERILELCSIACNKNTVPGDKSALNPSGVRLGTPALTTR 443
GG+D HL LVDLRS G G E++LE CSIACNKNT PGD+SAL PSG+RLGTPALT+R
Sbjct: 272 GGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSR 331
Query: 444 GLKESDIDXVVNYIDQALKIAQTIVEVSG 530
GL E D V ++I + +++ I +G
Sbjct: 332 GLLEKDFQKVAHFIHRGIELTLQIQSDTG 360
>Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 347
Score = 91.5 bits (217), Expect = 2e-18
Identities = 43/84 (51%), Positives = 55/84 (65%), Gaps = 1/84 (1%)
Frame = +3
Query: 3 AGVIFFRKGVRSVKAN-GQKVMYDFEGKINQAVFPGLQGGPHNHXXXXXXXXMKQATSPE 179
AG+IF+RKGV+SV G++++Y+ E IN AVFPGLQGGPHNH +KQA + E
Sbjct: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
Query: 180 FIEYQKQVIKNAQRLCEGLISRGY 251
F YQ QV+ N + L E L GY
Sbjct: 324 FKVYQHQVVANCRALSEALTELGY 347
>Y14489-1|CAB54842.1| 92|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 92
Score = 53.2 bits (122), Expect = 6e-07
Identities = 24/49 (48%), Positives = 34/49 (69%)
Frame = +3
Query: 384 DKSALNPSGVRLGTPALTTRGLKESDIDXVVNYIDQALKIAQTIVEVSG 530
D+SAL PSG+RLGTPALT+RGL E D V ++I + +++ I +G
Sbjct: 1 DRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTG 49
>BX119957-17|CAM25921.1| 433|Homo sapiens chromosome 6 open reading
frame 136 protein.
Length = 433
Score = 29.5 bits (63), Expect = 8.9
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Frame = -3
Query: 418 SLTPLGLRALLSPGTVFLLQAILHSSRIRSPGAPV--SPTLRKSTSARCTSVPPVAI 254
S TP G L PGT+ HS+ SP +P+ SP + + R VPP+ +
Sbjct: 135 SRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPL 191
>BC064397-1|AAH64397.1| 433|Homo sapiens C6orf136 protein protein.
Length = 433
Score = 29.5 bits (63), Expect = 8.9
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Frame = -3
Query: 418 SLTPLGLRALLSPGTVFLLQAILHSSRIRSPGAPV--SPTLRKSTSARCTSVPPVAI 254
S TP G L PGT+ HS+ SP +P+ SP + + R VPP+ +
Sbjct: 135 SRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPL 191
>AL732442-10|CAI17760.2| 433|Homo sapiens chromosome 6 open reading
frame 136 protein.
Length = 433
Score = 29.5 bits (63), Expect = 8.9
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Frame = -3
Query: 418 SLTPLGLRALLSPGTVFLLQAILHSSRIRSPGAPV--SPTLRKSTSARCTSVPPVAI 254
S TP G L PGT+ HS+ SP +P+ SP + + R VPP+ +
Sbjct: 135 SRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPL 191
>AL662800-21|CAI95540.2| 433|Homo sapiens chromosome 6 open reading
frame 136 protein.
Length = 433
Score = 29.5 bits (63), Expect = 8.9
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Frame = -3
Query: 418 SLTPLGLRALLSPGTVFLLQAILHSSRIRSPGAPV--SPTLRKSTSARCTSVPPVAI 254
S TP G L PGT+ HS+ SP +P+ SP + + R VPP+ +
Sbjct: 135 SRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPL 191
>AL662798-7|CAI95541.2| 433|Homo sapiens chromosome 6 open reading
frame 136 protein.
Length = 433
Score = 29.5 bits (63), Expect = 8.9
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Frame = -3
Query: 418 SLTPLGLRALLSPGTVFLLQAILHSSRIRSPGAPV--SPTLRKSTSARCTSVPPVAI 254
S TP G L PGT+ HS+ SP +P+ SP + + R VPP+ +
Sbjct: 135 SRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPL 191
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,470,804
Number of Sequences: 237096
Number of extensions: 1900539
Number of successful extensions: 4570
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 4271
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4553
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5929224630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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