Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0004_M03
(462 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 50 5e-06
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 50 5e-06
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 50 5e-06
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 50 5e-06
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 50 5e-06
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 50 5e-06
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 44 3e-04
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 44 3e-04
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 44 3e-04
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 44 3e-04
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 44 3e-04
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 43 4e-04
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 38 0.017
AL022152-2|CAD27434.1| 1142|Homo sapiens melanoma antigen family... 31 1.5
AK128570-1|BAC87504.1| 851|Homo sapiens protein ( Homo sapiens ... 31 1.5
AF064589-1|AAC18837.1| 1142|Homo sapiens melanoma-associated ant... 31 1.5
AF056334-1|AAC24227.1| 1142|Homo sapiens cancer/testis antigen C... 31 1.5
BC060796-1|AAH60796.1| 684|Homo sapiens coiled-coil domain cont... 30 4.5
AY254201-1|AAP13075.1| 682|Homo sapiens aaa-protein protein. 30 4.5
AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein. 30 4.5
AY009105-1|AAG49396.1| 497|Homo sapiens testis-specific protein... 30 4.5
AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette tr... 30 4.5
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 49.6 bits (113), Expect = 5e-06
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 241 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 411
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 182
Query: 412 DFRELRINSTDIYDYPR 462
+ IN + I D PR
Sbjct: 183 SYGTFTINESTIIDSPR 199
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 49.6 bits (113), Expect = 5e-06
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 241 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 411
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 112 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 170
Query: 412 DFRELRINSTDIYDYPR 462
+ IN + I D PR
Sbjct: 171 SYGTFTINESTIIDSPR 187
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 49.6 bits (113), Expect = 5e-06
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 241 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 411
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 140 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 198
Query: 412 DFRELRINSTDIYDYPR 462
+ IN + I D PR
Sbjct: 199 SYGTFTINESTIIDSPR 215
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 49.6 bits (113), Expect = 5e-06
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 241 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 411
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 182
Query: 412 DFRELRINSTDIYDYPR 462
+ IN + I D PR
Sbjct: 183 SYGTFTINESTIIDSPR 199
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 49.6 bits (113), Expect = 5e-06
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 241 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 411
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 182
Query: 412 DFRELRINSTDIYDYPR 462
+ IN + I D PR
Sbjct: 183 SYGTFTINESTIIDSPR 199
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 49.6 bits (113), Expect = 5e-06
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 241 VQELHVELT--APCEKLPYFGMDESYNLXXXX-XXXXXXXXIWGVIRGLETWSQLFYLTN 411
VQ+L V +T + C+ P DESY L +WG +RGLET+SQL Y +
Sbjct: 124 VQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY-QD 182
Query: 412 DFRELRINSTDIYDYPR 462
+ IN + I D PR
Sbjct: 183 SYGTFTINESTIIDSPR 199
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 43.6 bits (98), Expect = 3e-04
Identities = 46/163 (28%), Positives = 70/163 (42%), Gaps = 9/163 (5%)
Frame = +1
Query: 1 VWPKPQ-IQVKDDKY------YTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITR 159
+WP PQ Q D +Y + F V + +P C L +A +RY RDL +
Sbjct: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQP--GCSVLDEAFQRY----RDLLFGSG 76
Query: 160 RFVKRSLGSQYRSLDDEAANDERFQGTVQELHVELTAP-CEKLPYFGMDESYNLXXXXXX 336
+ + L + +L+ L V + P C +LP E+Y L
Sbjct: 77 SWPRPYLTGKRHTLEKNV------------LVVSVVTPGCNQLPTLESVENYTLTINDDQ 124
Query: 337 -XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINSTDIYDYPR 462
+WG +RGLET+SQL + + + IN T+I D+PR
Sbjct: 125 CLLLSETVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPR 166
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 43.6 bits (98), Expect = 3e-04
Identities = 46/163 (28%), Positives = 70/163 (42%), Gaps = 9/163 (5%)
Frame = +1
Query: 1 VWPKPQ-IQVKDDKY------YTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITR 159
+WP PQ Q D +Y + F V + +P C L +A +RY RDL +
Sbjct: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQP--GCSVLDEAFQRY----RDLLFGSG 76
Query: 160 RFVKRSLGSQYRSLDDEAANDERFQGTVQELHVELTAP-CEKLPYFGMDESYNLXXXXXX 336
+ + L + +L+ L V + P C +LP E+Y L
Sbjct: 77 SWPRPYLTGKRHTLEKNV------------LVVSVVTPGCNQLPTLESVENYTLTINDDQ 124
Query: 337 -XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINSTDIYDYPR 462
+WG +RGLET+SQL + + + IN T+I D+PR
Sbjct: 125 CLLLSETVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPR 166
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 43.6 bits (98), Expect = 3e-04
Identities = 46/163 (28%), Positives = 70/163 (42%), Gaps = 9/163 (5%)
Frame = +1
Query: 1 VWPKPQ-IQVKDDKY------YTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITR 159
+WP PQ Q D +Y + F V + +P C L +A +RY RDL +
Sbjct: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQP--GCSVLDEAFQRY----RDLLFGSG 76
Query: 160 RFVKRSLGSQYRSLDDEAANDERFQGTVQELHVELTAP-CEKLPYFGMDESYNLXXXXXX 336
+ + L + +L+ L V + P C +LP E+Y L
Sbjct: 77 SWPRPYLTGKRHTLEKNV------------LVVSVVTPGCNQLPTLESVENYTLTINDDQ 124
Query: 337 -XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINSTDIYDYPR 462
+WG +RGLET+SQL + + + IN T+I D+PR
Sbjct: 125 CLLLSETVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPR 166
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 43.6 bits (98), Expect = 3e-04
Identities = 46/163 (28%), Positives = 70/163 (42%), Gaps = 9/163 (5%)
Frame = +1
Query: 1 VWPKPQ-IQVKDDKY------YTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITR 159
+WP PQ Q D +Y + F V + +P C L +A +RY RDL +
Sbjct: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQP--GCSVLDEAFQRY----RDLLFGSG 76
Query: 160 RFVKRSLGSQYRSLDDEAANDERFQGTVQELHVELTAP-CEKLPYFGMDESYNLXXXXXX 336
+ + L + +L+ L V + P C +LP E+Y L
Sbjct: 77 SWPRPYLTGKRHTLEKNV------------LVVSVVTPGCNQLPTLESVENYTLTINDDQ 124
Query: 337 -XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINSTDIYDYPR 462
+WG +RGLET+SQL + + + IN T+I D+PR
Sbjct: 125 CLLLSETVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPR 166
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 43.6 bits (98), Expect = 3e-04
Identities = 46/163 (28%), Positives = 70/163 (42%), Gaps = 9/163 (5%)
Frame = +1
Query: 1 VWPKPQ-IQVKDDKY------YTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITR 159
+WP PQ Q D +Y + F V + +P C L +A +RY RDL +
Sbjct: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQP--GCSVLDEAFQRY----RDLLFGSG 76
Query: 160 RFVKRSLGSQYRSLDDEAANDERFQGTVQELHVELTAP-CEKLPYFGMDESYNLXXXXXX 336
+ + L + +L+ L V + P C +LP E+Y L
Sbjct: 77 SWPRPYLTGKRHTLEKNV------------LVVSVVTPGCNQLPTLESVENYTLTINDDQ 124
Query: 337 -XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINSTDIYDYPR 462
+WG +RGLET+SQL + + + IN T+I D+PR
Sbjct: 125 CLLLSETVWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPR 166
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 43.2 bits (97), Expect = 4e-04
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Frame = +1
Query: 262 LTAPCEKLPYFGMDESYNLXXXXXX-XXXXXXIWGVIRGLETWSQLFYLTNDFRELRINS 438
+T C +LP E+Y L +WG +RGLET+SQL + + + IN
Sbjct: 61 VTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE-GTFFINK 119
Query: 439 TDIYDYPR 462
T+I D+PR
Sbjct: 120 TEIEDFPR 127
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 37.9 bits (84), Expect = 0.017
Identities = 17/36 (47%), Positives = 25/36 (69%)
Frame = +1
Query: 355 IWGVIRGLETWSQLFYLTNDFRELRINSTDIYDYPR 462
+WG +RGLET+SQL + + + IN T+I D+PR
Sbjct: 12 VWGALRGLETFSQLVWKSAE-GTFFINKTEIEDFPR 46
>AL022152-2|CAD27434.1| 1142|Homo sapiens melanoma antigen family C, 1
protein.
Length = 1142
Score = 31.5 bits (68), Expect = 1.5
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +1
Query: 28 KDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDD 207
K D+ F + VK+P K + LT + RY + R R F++ G R +D
Sbjct: 911 KVDELARFLLLKYQVKQPITKAEMLTNVISRYTGYFPVIFRKAREFIEILFGISLREVDP 970
Query: 208 E 210
+
Sbjct: 971 D 971
>AK128570-1|BAC87504.1| 851|Homo sapiens protein ( Homo sapiens
cDNA FLJ46729 fis, clone TRACH3019370, weakly similar
to ATP-binding cassette, sub-family A, member 1. ).
Length = 851
Score = 31.5 bits (68), Expect = 1.5
Identities = 19/91 (20%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Frame = +1
Query: 49 FDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDDEAANDER 228
+ P + + QK ++ +++ + L L +T F + G + L + N
Sbjct: 75 YTPNTPEINKVIQKANYTFYIVDKLKTLSETLLEMTSLFQRSGSGQMFNQLQEALRNKFV 134
Query: 229 FQGTVQELHVELTAPCEKLPYFG--MDESYN 315
+LH+++ EKL +G +DE +N
Sbjct: 135 RNFVENQLHIDVDKLTEKLQTYGGLLDEMFN 165
>AF064589-1|AAC18837.1| 1142|Homo sapiens melanoma-associated antigen
protein.
Length = 1142
Score = 31.5 bits (68), Expect = 1.5
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +1
Query: 28 KDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDD 207
K D+ F + VK+P K + LT + RY + R R F++ G R +D
Sbjct: 911 KVDELARFLLLKYQVKQPITKAEMLTNVISRYTGYFPVIFRKAREFIEILFGISLREVDP 970
Query: 208 E 210
+
Sbjct: 971 D 971
>AF056334-1|AAC24227.1| 1142|Homo sapiens cancer/testis antigen CT7
protein.
Length = 1142
Score = 31.5 bits (68), Expect = 1.5
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +1
Query: 28 KDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDD 207
K D+ F + VK+P K + LT + RY + R R F++ G R +D
Sbjct: 911 KVDELARFLLLKYQVKQPITKAEMLTNVISRYTGYFPVIFRKAREFIEILFGISLREVDP 970
Query: 208 E 210
+
Sbjct: 971 D 971
>BC060796-1|AAH60796.1| 684|Homo sapiens coiled-coil domain
containing 62 protein.
Length = 684
Score = 29.9 bits (64), Expect = 4.5
Identities = 16/68 (23%), Positives = 35/68 (51%)
Frame = +1
Query: 19 IQVKDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRS 198
I++K +K D +FTV+ +K + L A + + +LH + + +VK+ Q+ +
Sbjct: 241 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 300
Query: 199 LDDEAAND 222
+ E + +
Sbjct: 301 FNVENSQE 308
>AY254201-1|AAP13075.1| 682|Homo sapiens aaa-protein protein.
Length = 682
Score = 29.9 bits (64), Expect = 4.5
Identities = 16/68 (23%), Positives = 35/68 (51%)
Frame = +1
Query: 19 IQVKDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRS 198
I++K +K D +FTV+ +K + L A + + +LH + + +VK+ Q+ +
Sbjct: 241 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 300
Query: 199 LDDEAAND 222
+ E + +
Sbjct: 301 FNVENSQE 308
>AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein.
Length = 5058
Score = 29.9 bits (64), Expect = 4.5
Identities = 18/91 (19%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Frame = +1
Query: 49 FDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDDEAANDER 228
+ P + + QK ++ +++ + L L ++ F + G + L + N
Sbjct: 3320 YTPNTPEINKVIQKANYTFYIVDKLKTLSETLLEMSSLFQRSGSGQMFNQLQEALRNKFV 3379
Query: 229 FQGTVQELHVELTAPCEKLPYFG--MDESYN 315
+LH+++ EKL +G +DE +N
Sbjct: 3380 RNFVENQLHIDVDKLTEKLQTYGGLLDEMFN 3410
>AY009105-1|AAG49396.1| 497|Homo sapiens testis-specific protein
TSP-NY protein.
Length = 497
Score = 29.9 bits (64), Expect = 4.5
Identities = 16/68 (23%), Positives = 35/68 (51%)
Frame = +1
Query: 19 IQVKDDKYYTFDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRS 198
I++K +K D +FTV+ +K + L A + + +LH + + +VK+ Q+ +
Sbjct: 56 IRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLN 115
Query: 199 LDDEAAND 222
+ E + +
Sbjct: 116 FNVENSQE 123
>AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette
transporter A13 protein.
Length = 2127
Score = 29.9 bits (64), Expect = 4.5
Identities = 18/91 (19%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Frame = +1
Query: 49 FDPAVFTVKEPFQKCDFLTKALERYQFLVRDLHRITRRFVKRSLGSQYRSLDDEAANDER 228
+ P + + QK ++ +++ + L L ++ F + G + L + N
Sbjct: 388 YTPNTPEINKVIQKANYTFYIVDKLKTLSETLLEMSSLFQRSGSGQMFNQLQEALRNKFV 447
Query: 229 FQGTVQELHVELTAPCEKLPYFG--MDESYN 315
+LH+++ EKL +G +DE +N
Sbjct: 448 RNFVENQLHIDVDKLTEKLQTYGGLLDEMFN 478
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 65,979,152
Number of Sequences: 237096
Number of extensions: 1264451
Number of successful extensions: 2714
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 2656
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2714
length of database: 76,859,062
effective HSP length: 84
effective length of database: 56,942,998
effective search space used: 3929066862
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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