Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0004_K20
(539 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine hydroxym... 134 2e-31
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 134 2e-31
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 134 2e-31
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 134 2e-31
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 134 2e-31
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 134 2e-31
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 134 2e-31
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 134 2e-31
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 134 2e-31
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 134 2e-31
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 124 3e-28
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 124 3e-28
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 124 3e-28
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 124 3e-28
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 124 3e-28
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 124 3e-28
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 124 3e-28
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 124 3e-28
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 64 2e-10
Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein. 60 4e-09
AK055053-1|BAB70847.1| 135|Homo sapiens protein. 37 0.039
BC028594-1|AAH28594.1| 167|Homo sapiens SERAC1 protein protein. 29 7.9
BC001705-1|AAH01705.1| 654|Homo sapiens serine active site cont... 29 7.9
AL590703-2|CAH70240.1| 531|Homo sapiens serine active site cont... 29 7.9
AL590703-1|CAH70239.1| 654|Homo sapiens serine active site cont... 29 7.9
AL135907-2|CAI42500.1| 531|Homo sapiens serine active site cont... 29 7.9
AL135907-1|CAI42499.1| 654|Homo sapiens serine active site cont... 29 7.9
AK027823-1|BAB55393.1| 654|Homo sapiens protein ( Homo sapiens ... 29 7.9
>Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 347
Score = 134 bits (324), Expect = 2e-31
Identities = 61/100 (61%), Positives = 78/100 (78%)
Frame = +3
Query: 93 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 272
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 273 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQP
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQP 117
Score = 66.1 bits (154), Expect = 7e-11
Identities = 28/30 (93%), Positives = 29/30 (96%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPANFAVYT +VEPHGRIMGLDLPDGG
Sbjct: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 134 bits (324), Expect = 2e-31
Identities = 61/100 (61%), Positives = 78/100 (78%)
Frame = +3
Query: 93 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 272
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 273 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQP
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQP 117
Score = 66.1 bits (154), Expect = 7e-11
Identities = 28/30 (93%), Positives = 29/30 (96%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPANFAVYT +VEPHGRIMGLDLPDGG
Sbjct: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 134 bits (324), Expect = 2e-31
Identities = 61/100 (61%), Positives = 78/100 (78%)
Frame = +3
Query: 93 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 272
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 273 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQP
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQP 117
Score = 66.1 bits (154), Expect = 7e-11
Identities = 28/30 (93%), Positives = 29/30 (96%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPANFAVYT +VEPHGRIMGLDLPDGG
Sbjct: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 134 bits (324), Expect = 2e-31
Identities = 61/100 (61%), Positives = 78/100 (78%)
Frame = +3
Query: 93 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 272
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 273 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQP
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQP 117
Score = 66.1 bits (154), Expect = 7e-11
Identities = 28/30 (93%), Positives = 29/30 (96%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPANFAVYT +VEPHGRIMGLDLPDGG
Sbjct: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 134 bits (324), Expect = 2e-31
Identities = 61/100 (61%), Positives = 78/100 (78%)
Frame = +3
Query: 93 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 272
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 273 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQP
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQP 117
Score = 66.1 bits (154), Expect = 7e-11
Identities = 28/30 (93%), Positives = 29/30 (96%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPANFAVYT +VEPHGRIMGLDLPDGG
Sbjct: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 134 bits (324), Expect = 2e-31
Identities = 61/100 (61%), Positives = 78/100 (78%)
Frame = +3
Query: 93 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 272
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 273 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQP
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQP 117
Score = 66.1 bits (154), Expect = 7e-11
Identities = 28/30 (93%), Positives = 29/30 (96%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPANFAVYT +VEPHGRIMGLDLPDGG
Sbjct: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 134 bits (324), Expect = 2e-31
Identities = 61/100 (61%), Positives = 78/100 (78%)
Frame = +3
Query: 93 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 272
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 273 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQP
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQP 117
Score = 66.1 bits (154), Expect = 7e-11
Identities = 28/30 (93%), Positives = 29/30 (96%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPANFAVYT +VEPHGRIMGLDLPDGG
Sbjct: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 134 bits (324), Expect = 2e-31
Identities = 61/100 (61%), Positives = 78/100 (78%)
Frame = +3
Query: 93 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 272
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 273 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQP
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQP 117
Score = 66.1 bits (154), Expect = 7e-11
Identities = 28/30 (93%), Positives = 29/30 (96%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPANFAVYT +VEPHGRIMGLDLPDGG
Sbjct: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 134 bits (324), Expect = 2e-31
Identities = 61/100 (61%), Positives = 78/100 (78%)
Frame = +3
Query: 93 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 272
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 273 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQP
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQP 117
Score = 66.1 bits (154), Expect = 7e-11
Identities = 28/30 (93%), Positives = 29/30 (96%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPANFAVYT +VEPHGRIMGLDLPDGG
Sbjct: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 134 bits (324), Expect = 2e-31
Identities = 61/100 (61%), Positives = 78/100 (78%)
Frame = +3
Query: 93 NNKLLNGNLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGM 272
++K+L L ++D E++N+I KE RQ+ GLE+IASENF S VL+ L SCL+NKYSEG
Sbjct: 18 HDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGY 77
Query: 273 PYQRYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
P QRYYGG EFIDE+E L Q R+L+ YKL+P+ WGVNVQP
Sbjct: 78 PGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQP 117
Score = 66.1 bits (154), Expect = 7e-11
Identities = 28/30 (93%), Positives = 29/30 (96%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPANFAVYT +VEPHGRIMGLDLPDGG
Sbjct: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 124 bits (298), Expect = 3e-28
Identities = 55/93 (59%), Positives = 72/93 (77%)
Frame = +3
Query: 114 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 293
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 27 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 86
Query: 294 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
G E +DEIE+L Q R+LE + L+P +WGVNVQP
Sbjct: 87 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQP 119
Score = 58.4 bits (135), Expect = 1e-08
Identities = 24/30 (80%), Positives = 27/30 (90%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 120 YSGSPANLAVYTALLQPHDRIMGLDLPDGG 149
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 124 bits (298), Expect = 3e-28
Identities = 55/93 (59%), Positives = 72/93 (77%)
Frame = +3
Query: 114 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 293
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 18 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 77
Query: 294 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
G E +DEIE+L Q R+LE + L+P +WGVNVQP
Sbjct: 78 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQP 110
Score = 58.4 bits (135), Expect = 1e-08
Identities = 24/30 (80%), Positives = 27/30 (90%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 111 YSGSPANLAVYTALLQPHDRIMGLDLPDGG 140
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 124 bits (298), Expect = 3e-28
Identities = 55/93 (59%), Positives = 72/93 (77%)
Frame = +3
Query: 114 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 293
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 294 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
G E +DEIE+L Q R+LE + L+P +WGVNVQP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQP 140
Score = 58.4 bits (135), Expect = 1e-08
Identities = 24/30 (80%), Positives = 27/30 (90%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 141 YSGSPANLAVYTALLQPHDRIMGLDLPDGG 170
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 124 bits (298), Expect = 3e-28
Identities = 55/93 (59%), Positives = 72/93 (77%)
Frame = +3
Query: 114 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 293
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 294 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
G E +DEIE+L Q R+LE + L+P +WGVNVQP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQP 140
Score = 58.4 bits (135), Expect = 1e-08
Identities = 24/30 (80%), Positives = 27/30 (90%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 141 YSGSPANLAVYTALLQPHDRIMGLDLPDGG 170
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 124 bits (298), Expect = 3e-28
Identities = 55/93 (59%), Positives = 72/93 (77%)
Frame = +3
Query: 114 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 293
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 294 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
G E +DEIE+L Q R+LE + L+P +WGVNVQP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQP 140
Score = 58.4 bits (135), Expect = 1e-08
Identities = 24/30 (80%), Positives = 27/30 (90%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 141 YSGSPANLAVYTALLQPHDRIMGLDLPDGG 170
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 124 bits (298), Expect = 3e-28
Identities = 55/93 (59%), Positives = 72/93 (77%)
Frame = +3
Query: 114 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 293
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 294 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
G E +DEIE+L Q R+LE + L+P +WGVNVQP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQP 140
Score = 58.4 bits (135), Expect = 1e-08
Identities = 24/30 (80%), Positives = 27/30 (90%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 141 YSGSPANLAVYTALLQPHDRIMGLDLPDGG 170
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 124 bits (298), Expect = 3e-28
Identities = 55/93 (59%), Positives = 72/93 (77%)
Frame = +3
Query: 114 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 293
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 294 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
G E +DEIE+L Q R+LE + L+P +WGVNVQP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQP 140
Score = 58.4 bits (135), Expect = 1e-08
Identities = 24/30 (80%), Positives = 27/30 (90%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 141 YSGSPANLAVYTALLQPHDRIMGLDLPDGG 170
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 124 bits (298), Expect = 3e-28
Identities = 55/93 (59%), Positives = 72/93 (77%)
Frame = +3
Query: 114 NLWETDPELFNLITKEKKRQQAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 293
+L ++DPE++ L+ +EK RQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 294 GNEFIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
G E +DEIE+L Q R+LE + L+P +WGVNVQP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQP 140
Score = 58.4 bits (135), Expect = 1e-08
Identities = 24/30 (80%), Positives = 27/30 (90%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 141 YSGSPANLAVYTALLQPHDRIMGLDLPDGG 170
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 64.5 bits (150), Expect = 2e-10
Identities = 35/90 (38%), Positives = 50/90 (55%), Gaps = 6/90 (6%)
Frame = +3
Query: 141 FNLITKEKKRQQAGLEMIASE--NFTSVPVLQCLSSCLHNKYSEGMPY----QRYYGGNE 302
F L T + R + G + A + +L+C S C + + + QRYYGG E
Sbjct: 27 FGLSTATQPRLRLGKQTGAGQARRACRTVILRCGSCCRGRRTGSVVAWSSLPQRYYGGAE 86
Query: 303 FIDEIEILAQNRSLETYKLNPEEWGVNVQP 392
+DEIE+L Q R+LE + L+P +WGVNVQP
Sbjct: 87 VVDEIELLCQRRALEAFDLDPAQWGVNVQP 116
Score = 58.4 bits (135), Expect = 1e-08
Identities = 24/30 (80%), Positives = 27/30 (90%)
Frame = +1
Query: 394 YSGSPANFAVYTGVVEPHGRIMGLDLPDGG 483
YSGSPAN AVYT +++PH RIMGLDLPDGG
Sbjct: 117 YSGSPANLAVYTALLQPHDRIMGLDLPDGG 146
>Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein.
Length = 129
Score = 60.5 bits (140), Expect = 4e-09
Identities = 27/57 (47%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Frame = +3
Query: 282 RYYGGNEFIDEIEILAQNRSLETYKLNPEEWGVNVQPLFRVASKLCCLY-GCC*TAW 449
RYYGG EFIDE+E L Q R+L+ YKL+P+ WGV+V P + S + + C + W
Sbjct: 65 RYYGGTEFIDELETLCQKRALQAYKLDPQCWGVDVHPTQVLVSSIWLVQASSCASPW 121
>AK055053-1|BAB70847.1| 135|Homo sapiens protein.
Length = 135
Score = 37.1 bits (82), Expect = 0.039
Identities = 16/30 (53%), Positives = 24/30 (80%)
Frame = +3
Query: 114 NLWETDPELFNLITKEKKRQQAGLEMIASE 203
+L ++DPE++ L+ +EK RQ GLE+IASE
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASE 77
>BC028594-1|AAH28594.1| 167|Homo sapiens SERAC1 protein protein.
Length = 167
Score = 29.5 bits (63), Expect = 7.9
Identities = 9/16 (56%), Positives = 12/16 (75%)
Frame = -1
Query: 524 YCLVCCKRIHGSNGPP 477
YC++CC+RI S PP
Sbjct: 6 YCVICCRRIGTSTSPP 21
>BC001705-1|AAH01705.1| 654|Homo sapiens serine active site
containing 1 protein.
Length = 654
Score = 29.5 bits (63), Expect = 7.9
Identities = 9/16 (56%), Positives = 12/16 (75%)
Frame = -1
Query: 524 YCLVCCKRIHGSNGPP 477
YC++CC+RI S PP
Sbjct: 6 YCVICCRRIGTSTSPP 21
>AL590703-2|CAH70240.1| 531|Homo sapiens serine active site
containing 1 protein.
Length = 531
Score = 29.5 bits (63), Expect = 7.9
Identities = 9/16 (56%), Positives = 12/16 (75%)
Frame = -1
Query: 524 YCLVCCKRIHGSNGPP 477
YC++CC+RI S PP
Sbjct: 6 YCVICCRRIGTSTSPP 21
>AL590703-1|CAH70239.1| 654|Homo sapiens serine active site
containing 1 protein.
Length = 654
Score = 29.5 bits (63), Expect = 7.9
Identities = 9/16 (56%), Positives = 12/16 (75%)
Frame = -1
Query: 524 YCLVCCKRIHGSNGPP 477
YC++CC+RI S PP
Sbjct: 6 YCVICCRRIGTSTSPP 21
>AL135907-2|CAI42500.1| 531|Homo sapiens serine active site
containing 1 protein.
Length = 531
Score = 29.5 bits (63), Expect = 7.9
Identities = 9/16 (56%), Positives = 12/16 (75%)
Frame = -1
Query: 524 YCLVCCKRIHGSNGPP 477
YC++CC+RI S PP
Sbjct: 6 YCVICCRRIGTSTSPP 21
>AL135907-1|CAI42499.1| 654|Homo sapiens serine active site
containing 1 protein.
Length = 654
Score = 29.5 bits (63), Expect = 7.9
Identities = 9/16 (56%), Positives = 12/16 (75%)
Frame = -1
Query: 524 YCLVCCKRIHGSNGPP 477
YC++CC+RI S PP
Sbjct: 6 YCVICCRRIGTSTSPP 21
>AK027823-1|BAB55393.1| 654|Homo sapiens protein ( Homo sapiens
cDNA FLJ14917 fis, clone PLACE1007112. ).
Length = 654
Score = 29.5 bits (63), Expect = 7.9
Identities = 9/16 (56%), Positives = 12/16 (75%)
Frame = -1
Query: 524 YCLVCCKRIHGSNGPP 477
YC++CC+RI S PP
Sbjct: 6 YCVICCRRIGTSTSPP 21
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 82,637,834
Number of Sequences: 237096
Number of extensions: 1744221
Number of successful extensions: 4025
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 3918
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4025
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5251598958
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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