Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0003_O01
(543 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine hydroxym... 243 3e-64
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 243 3e-64
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 243 3e-64
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 243 3e-64
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 243 3e-64
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 243 3e-64
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 243 3e-64
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 243 3e-64
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 243 3e-64
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 243 3e-64
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 217 3e-56
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 217 3e-56
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 217 3e-56
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 217 3e-56
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 217 3e-56
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 217 3e-56
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 217 3e-56
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 217 3e-56
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 189 6e-48
Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine hydroxym... 91 2e-18
Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein. 48 3e-05
>Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 347
Score = 243 bits (595), Expect = 3e-64
Identities = 111/146 (76%), Positives = 126/146 (86%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHG IMGLDLPDG
Sbjct: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHGF T KKISATSIF ESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYS
Sbjct: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R L+Y R R+IADENGAYLMADMAH+
Sbjct: 207 RNLEYARLRKIADENGAYLMADMAHI 232
Score = 52.0 bits (119), Expect = 1e-06
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S VL+ L SCL+NKYSEG P QRYYG
Sbjct: 53 SENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 243 bits (595), Expect = 3e-64
Identities = 111/146 (76%), Positives = 126/146 (86%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHG IMGLDLPDG
Sbjct: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHGF T KKISATSIF ESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYS
Sbjct: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R L+Y R R+IADENGAYLMADMAH+
Sbjct: 207 RNLEYARLRKIADENGAYLMADMAHI 232
Score = 52.0 bits (119), Expect = 1e-06
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S VL+ L SCL+NKYSEG P QRYYG
Sbjct: 53 SENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 243 bits (595), Expect = 3e-64
Identities = 111/146 (76%), Positives = 126/146 (86%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHG IMGLDLPDG
Sbjct: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHGF T KKISATSIF ESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYS
Sbjct: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R L+Y R R+IADENGAYLMADMAH+
Sbjct: 207 RNLEYARLRKIADENGAYLMADMAHI 232
Score = 52.0 bits (119), Expect = 1e-06
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S VL+ L SCL+NKYSEG P QRYYG
Sbjct: 53 SENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 243 bits (595), Expect = 3e-64
Identities = 111/146 (76%), Positives = 126/146 (86%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHG IMGLDLPDG
Sbjct: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHGF T KKISATSIF ESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYS
Sbjct: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R L+Y R R+IADENGAYLMADMAH+
Sbjct: 207 RNLEYARLRKIADENGAYLMADMAHI 232
Score = 52.0 bits (119), Expect = 1e-06
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S VL+ L SCL+NKYSEG P QRYYG
Sbjct: 53 SENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 243 bits (595), Expect = 3e-64
Identities = 111/146 (76%), Positives = 126/146 (86%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHG IMGLDLPDG
Sbjct: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHGF T KKISATSIF ESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYS
Sbjct: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R L+Y R R+IADENGAYLMADMAH+
Sbjct: 207 RNLEYARLRKIADENGAYLMADMAHI 232
Score = 52.0 bits (119), Expect = 1e-06
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S VL+ L SCL+NKYSEG P QRYYG
Sbjct: 53 SENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 243 bits (595), Expect = 3e-64
Identities = 111/146 (76%), Positives = 126/146 (86%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHG IMGLDLPDG
Sbjct: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHGF T KKISATSIF ESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYS
Sbjct: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R L+Y R R+IADENGAYLMADMAH+
Sbjct: 207 RNLEYARLRKIADENGAYLMADMAHI 232
Score = 52.0 bits (119), Expect = 1e-06
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S VL+ L SCL+NKYSEG P QRYYG
Sbjct: 53 SENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 243 bits (595), Expect = 3e-64
Identities = 111/146 (76%), Positives = 126/146 (86%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHG IMGLDLPDG
Sbjct: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHGF T KKISATSIF ESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYS
Sbjct: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R L+Y R R+IADENGAYLMADMAH+
Sbjct: 207 RNLEYARLRKIADENGAYLMADMAHI 232
Score = 52.0 bits (119), Expect = 1e-06
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S VL+ L SCL+NKYSEG P QRYYG
Sbjct: 53 SENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 243 bits (595), Expect = 3e-64
Identities = 111/146 (76%), Positives = 126/146 (86%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHG IMGLDLPDG
Sbjct: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHGF T KKISATSIF ESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYS
Sbjct: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R L+Y R R+IADENGAYLMADMAH+
Sbjct: 207 RNLEYARLRKIADENGAYLMADMAHI 232
Score = 52.0 bits (119), Expect = 1e-06
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S VL+ L SCL+NKYSEG P QRYYG
Sbjct: 53 SENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 243 bits (595), Expect = 3e-64
Identities = 111/146 (76%), Positives = 126/146 (86%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHG IMGLDLPDG
Sbjct: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHGF T KKISATSIF ESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYS
Sbjct: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R L+Y R R+IADENGAYLMADMAH+
Sbjct: 207 RNLEYARLRKIADENGAYLMADMAHI 232
Score = 52.0 bits (119), Expect = 1e-06
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S VL+ L SCL+NKYSEG P QRYYG
Sbjct: 53 SENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 243 bits (595), Expect = 3e-64
Identities = 111/146 (76%), Positives = 126/146 (86%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
EFIDE+E L Q R+L+ YKL+P+ WGVNVQPYSGSPANFAVYT +VEPHG IMGLDLPDG
Sbjct: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHGF T KKISATSIF ESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYS
Sbjct: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R L+Y R R+IADENGAYLMADMAH+
Sbjct: 207 RNLEYARLRKIADENGAYLMADMAHI 232
Score = 52.0 bits (119), Expect = 1e-06
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S VL+ L SCL+NKYSEG P QRYYG
Sbjct: 53 SENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 217 bits (529), Expect = 3e-56
Identities = 96/146 (65%), Positives = 122/146 (83%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH IMGLDLPDG
Sbjct: 89 EVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDG 148
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHG+ + K+ISATSIF ESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+
Sbjct: 149 GHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYA 208
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R +DY R R++ DE A+L+ADMAH+
Sbjct: 209 RLIDYARMREVCDEVKAHLLADMAHI 234
Score = 48.4 bits (110), Expect = 2e-05
Identities = 21/32 (65%), Positives = 24/32 (75%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 55 SENFCSRAALEALGSCLNNKYSEGYPGKRYYG 86
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 217 bits (529), Expect = 3e-56
Identities = 96/146 (65%), Positives = 122/146 (83%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH IMGLDLPDG
Sbjct: 80 EVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDG 139
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHG+ + K+ISATSIF ESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+
Sbjct: 140 GHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYA 199
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R +DY R R++ DE A+L+ADMAH+
Sbjct: 200 RLIDYARMREVCDEVKAHLLADMAHI 225
Score = 48.4 bits (110), Expect = 2e-05
Identities = 21/32 (65%), Positives = 24/32 (75%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 46 SENFCSRAALEALGSCLNNKYSEGYPGKRYYG 77
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 217 bits (529), Expect = 3e-56
Identities = 96/146 (65%), Positives = 122/146 (83%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH IMGLDLPDG
Sbjct: 110 EVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDG 169
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHG+ + K+ISATSIF ESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+
Sbjct: 170 GHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYA 229
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R +DY R R++ DE A+L+ADMAH+
Sbjct: 230 RLIDYARMREVCDEVKAHLLADMAHI 255
Score = 48.4 bits (110), Expect = 2e-05
Identities = 21/32 (65%), Positives = 24/32 (75%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 76 SENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 217 bits (529), Expect = 3e-56
Identities = 96/146 (65%), Positives = 122/146 (83%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH IMGLDLPDG
Sbjct: 86 EVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDG 145
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHG+ + K+ISATSIF ESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+
Sbjct: 146 GHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYA 205
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R +DY R R++ DE A+L+ADMAH+
Sbjct: 206 RLIDYARMREVCDEVKAHLLADMAHI 231
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 217 bits (529), Expect = 3e-56
Identities = 96/146 (65%), Positives = 122/146 (83%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH IMGLDLPDG
Sbjct: 110 EVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDG 169
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHG+ + K+ISATSIF ESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+
Sbjct: 170 GHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYA 229
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R +DY R R++ DE A+L+ADMAH+
Sbjct: 230 RLIDYARMREVCDEVKAHLLADMAHI 255
Score = 48.4 bits (110), Expect = 2e-05
Identities = 21/32 (65%), Positives = 24/32 (75%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 76 SENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 217 bits (529), Expect = 3e-56
Identities = 96/146 (65%), Positives = 122/146 (83%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH IMGLDLPDG
Sbjct: 110 EVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDG 169
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHG+ + K+ISATSIF ESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+
Sbjct: 170 GHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYA 229
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R +DY R R++ DE A+L+ADMAH+
Sbjct: 230 RLIDYARMREVCDEVKAHLLADMAHI 255
Score = 48.4 bits (110), Expect = 2e-05
Identities = 21/32 (65%), Positives = 24/32 (75%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 76 SENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 217 bits (529), Expect = 3e-56
Identities = 96/146 (65%), Positives = 122/146 (83%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH IMGLDLPDG
Sbjct: 110 EVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDG 169
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHG+ + K+ISATSIF ESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+
Sbjct: 170 GHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYA 229
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R +DY R R++ DE A+L+ADMAH+
Sbjct: 230 RLIDYARMREVCDEVKAHLLADMAHI 255
Score = 48.4 bits (110), Expect = 2e-05
Identities = 21/32 (65%), Positives = 24/32 (75%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 76 SENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 217 bits (529), Expect = 3e-56
Identities = 96/146 (65%), Positives = 122/146 (83%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH IMGLDLPDG
Sbjct: 110 EVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDG 169
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHG+ + K+ISATSIF ESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+
Sbjct: 170 GHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYA 229
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R +DY R R++ DE A+L+ADMAH+
Sbjct: 230 RLIDYARMREVCDEVKAHLLADMAHI 255
Score = 48.4 bits (110), Expect = 2e-05
Identities = 21/32 (65%), Positives = 24/32 (75%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 76 SENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 189 bits (460), Expect = 6e-48
Identities = 89/146 (60%), Positives = 113/146 (77%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQPYSGSPANFAVYTGVVEPHGTIMGLDLPDG 283
E +DEIE+L Q R+LE + L+P +WGVNVQPYSGSPAN AVYT +++PH IMGLDLPDG
Sbjct: 110 EVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDG 169
Query: 284 GHLTHGFFTANKKISATSIFCESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYS 463
GHLTHG+ + K+ISATSIF ESMPYK++ LA TA+LF+PR+IIAG S Y+
Sbjct: 170 GHLTHGYMSDVKRISATSIFFESMPYKLN----------LALTARLFRPRLIIAGTSAYA 219
Query: 464 RCLDY*RFRQIADENGAYLMADMAHV 541
R +DY R R++ DE A+L+ADMAH+
Sbjct: 220 RLIDYARMREVCDEVKAHLLADMAHI 245
Score = 48.4 bits (110), Expect = 2e-05
Identities = 21/32 (65%), Positives = 24/32 (75%)
Frame = +1
Query: 1 SENFTSVPVLQCLSSCLHNKYSEGMPYQRYYG 96
SENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 76 SENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
>Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 310
Score = 91.5 bits (217), Expect = 2e-18
Identities = 41/59 (69%), Positives = 50/59 (84%)
Frame = +2
Query: 365 VDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDY*RFRQIADENGAYLMADMAHV 541
V+P TG I+YD+L E A+LF P++IIAG SCYSR L+Y R R+IADENGAYLMADMAH+
Sbjct: 1 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHI 59
>Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein.
Length = 129
Score = 47.6 bits (108), Expect = 3e-05
Identities = 19/31 (61%), Positives = 25/31 (80%)
Frame = +2
Query: 104 EFIDEIEILAQNRSLETYKLNPEEWGVNVQP 196
EFIDE+E L Q R+L+ YKL+P+ WGV+V P
Sbjct: 71 EFIDELETLCQKRALQAYKLDPQCWGVDVHP 101
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,970,093
Number of Sequences: 237096
Number of extensions: 1720378
Number of successful extensions: 6630
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 6566
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6629
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5308067764
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -