Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0003_L18
(545 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA ... 215 6e-55
UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to 3-hydroxya... 182 5e-45
UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30; Coelom... 171 9e-42
UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella ve... 158 9e-38
UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|R... 142 5e-33
UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 123 2e-27
UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5; Alphaproteobacter... 117 2e-25
UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 116 4e-25
UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 110 2e-23
UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain ... 107 1e-22
UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3; ... 101 8e-21
UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 101 1e-20
UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN ful... 97 3e-19
UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 - Cl... 97 3e-19
UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3; ... 97 3e-19
UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 92 7e-18
UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 92 9e-18
UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 89 5e-17
UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 89 6e-17
UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 89 8e-17
UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 86 4e-16
UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 84 2e-15
UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 84 2e-15
UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4; S... 84 2e-15
UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 83 4e-15
UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 83 5e-15
UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2... 80 3e-14
UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6... 80 3e-14
UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; B... 80 4e-14
UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 80 4e-14
UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; A... 80 4e-14
UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 79 7e-14
UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 79 7e-14
UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; S... 78 1e-13
UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 78 2e-13
UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 78 2e-13
UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;... 77 2e-13
UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 77 2e-13
UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 77 4e-13
UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1; Bre... 76 6e-13
UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 76 6e-13
UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 75 1e-12
UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1; ... 75 1e-12
UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 73 3e-12
UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9; B... 73 3e-12
UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation m... 73 3e-12
UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1; ... 73 4e-12
UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24; ... 73 6e-12
UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 72 8e-12
UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 71 1e-11
UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase N... 71 2e-11
UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 70 4e-11
UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 70 4e-11
UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 69 5e-11
UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1; ... 69 5e-11
UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 69 9e-11
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 68 1e-10
UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 68 1e-10
UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,... 68 2e-10
UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 68 2e-10
UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 67 3e-10
UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 67 3e-10
UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 67 3e-10
UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like pr... 66 5e-10
UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 66 7e-10
UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 66 7e-10
UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precurs... 66 7e-10
UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 65 9e-10
UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3... 65 1e-09
UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex t... 65 1e-09
UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 64 2e-09
UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 64 2e-09
UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 64 2e-09
UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 64 2e-09
UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 64 2e-09
UniRef50_O69856 Cluster: Fatty acid oxidation complex alpha-subu... 64 2e-09
UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD bi... 64 3e-09
UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 63 4e-09
UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 62 6e-09
UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA dehydrogenase/3-hydro... 62 6e-09
UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; H... 62 6e-09
UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 62 8e-09
UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 62 8e-09
UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 62 8e-09
UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Re... 62 1e-08
UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole gen... 62 1e-08
UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; c... 62 1e-08
UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 61 1e-08
UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 61 1e-08
UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 61 1e-08
UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 61 1e-08
UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4; Trichoco... 61 1e-08
UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 60 2e-08
UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 60 2e-08
UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 60 3e-08
UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenas... 60 4e-08
UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 60 4e-08
UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 59 6e-08
UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 59 8e-08
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 58 1e-07
UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; P... 58 1e-07
UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 58 1e-07
UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 58 1e-07
UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-07
UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 58 1e-07
UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 58 1e-07
UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9; G... 58 1e-07
UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 57 2e-07
UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8... 57 3e-07
UniRef50_Q5LVG3 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 57 3e-07
UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;... 57 3e-07
UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase; ... 57 3e-07
UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 57 3e-07
UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 56 4e-07
UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 56 5e-07
UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein ... 56 5e-07
UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1; ... 56 5e-07
UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 56 5e-07
UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 56 5e-07
UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 56 7e-07
UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 56 7e-07
UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome. prec... 56 7e-07
UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation m... 56 7e-07
UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 55 9e-07
UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 54 2e-06
UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 54 2e-06
UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular organi... 54 2e-06
UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5; Tri... 54 2e-06
UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 54 3e-06
UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n... 53 4e-06
UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 53 4e-06
UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subun... 53 4e-06
UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella ve... 53 5e-06
UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep... 52 7e-06
UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 52 7e-06
UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 52 7e-06
UniRef50_Q5LVD0 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 52 9e-06
UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 52 9e-06
UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB... 52 9e-06
UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 52 9e-06
UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA... 52 1e-05
UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 52 1e-05
UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10; ... 51 2e-05
UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:... 51 2e-05
UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA dehy... 51 2e-05
UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 51 2e-05
UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 51 2e-05
UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 51 2e-05
UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA hydratase/3-hydroxya... 51 2e-05
UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 51 2e-05
UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 51 2e-05
UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 51 2e-05
UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2; Alphapr... 51 2e-05
UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 51 2e-05
UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit, mit... 50 3e-05
UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 50 4e-05
UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 4e-05
UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 4e-05
UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 50 5e-05
UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=3... 49 6e-05
UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 49 6e-05
UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16; ... 49 6e-05
UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48; ... 49 6e-05
UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 49 6e-05
UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 49 6e-05
UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 49 8e-05
UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified ... 49 8e-05
UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 1e-04
UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 48 1e-04
UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 48 1e-04
UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 1e-04
UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 48 2e-04
UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8; A... 48 2e-04
UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 47 2e-04
UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2; Bord... 47 2e-04
UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 47 3e-04
UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;... 46 4e-04
UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit ... 46 4e-04
UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 46 6e-04
UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 46 6e-04
UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit al... 46 6e-04
UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44; ... 46 8e-04
UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 46 8e-04
UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:... 46 8e-04
UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 45 0.001
UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 45 0.001
UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 45 0.001
UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 45 0.001
UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit ... 45 0.001
UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 45 0.001
UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 45 0.001
UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;... 45 0.001
UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 45 0.001
UniRef50_Q5P607 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 44 0.002
UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 44 0.002
UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;... 44 0.002
UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 44 0.002
UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 44 0.003
UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase r... 44 0.003
UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 43 0.004
UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; B... 43 0.004
UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 43 0.004
UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 43 0.004
UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;... 43 0.005
UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep: ... 42 0.007
UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3; Lacto... 42 0.007
UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 42 0.007
UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 42 0.007
UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 42 0.009
UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 42 0.009
UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius s... 42 0.009
UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2; Si... 42 0.009
UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 42 0.009
UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA dehydroge... 42 0.009
UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 42 0.012
UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 42 0.012
UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein NCU043... 42 0.012
UniRef50_Q0UJN7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 42 0.012
UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 41 0.016
UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 41 0.016
UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 41 0.016
UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit al... 41 0.016
UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit al... 41 0.016
UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;... 41 0.021
UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA dehydrogena... 41 0.021
UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 41 0.021
UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13; c... 41 0.021
UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 40 0.028
UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation c... 40 0.028
UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 40 0.028
UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 40 0.028
UniRef50_A2QA05 Cluster: Catalytic activity:; n=4; Trichocomacea... 40 0.028
UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3; Achol... 40 0.028
UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 40 0.038
UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1; A... 40 0.038
UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 40 0.038
UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 40 0.038
UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 40 0.038
UniRef50_A3T2M8 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 40 0.038
UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 40 0.050
UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 40 0.050
UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 40 0.050
UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;... 40 0.050
UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65; cell... 40 0.050
UniRef50_Q8CXB6 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ... 39 0.066
UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 39 0.066
UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; X... 39 0.087
UniRef50_A6LMV1 Cluster: Putative uncharacterized protein precur... 39 0.087
UniRef50_A5ZCW2 Cluster: Putative uncharacterized protein; n=1; ... 39 0.087
UniRef50_A3VIL7 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 39 0.087
UniRef50_A3LNF8 Cluster: Kynurenine 3-monooxygenase, mitochondri... 39 0.087
UniRef50_Q83EI9 Cluster: Thiamine biosynthesis oxidoreductase Th... 38 0.11
UniRef50_Q6MHW5 Cluster: Glucose-inhibited division protein; n=1... 38 0.11
UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 38 0.11
UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|R... 38 0.11
UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit al... 38 0.11
UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13; Baci... 38 0.11
UniRef50_Q2GH13 Cluster: FAD-dependent oxidoreductase; n=6; Anap... 38 0.15
UniRef50_Q97PL8 Cluster: Oxidoreductase, pyridine nucleotide-dis... 38 0.20
UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 38 0.20
UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 38 0.20
UniRef50_A3XPY3 Cluster: Putative uncharacterized protein; n=1; ... 38 0.20
UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4; Thermococ... 38 0.20
UniRef50_Q08426 Cluster: Peroxisomal bifunctional enzyme (PBE) (... 38 0.20
UniRef50_P38169 Cluster: Kynurenine 3-monooxygenase; n=4; Saccha... 38 0.20
UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC... 37 0.26
UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; V... 37 0.26
UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 37 0.26
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 37 0.26
UniRef50_Q485S6 Cluster: Putative D-amino acid dehydrogenase, sm... 37 0.35
UniRef50_Q490A1 Cluster: UDP-glucose 6-dehydrogenase; n=12; Stre... 37 0.35
UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 37 0.35
UniRef50_Q0TSZ8 Cluster: Transcriptional regulator, MarR family;... 37 0.35
UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 37 0.35
UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1; C... 36 0.46
UniRef50_Q1FP37 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 36 0.46
UniRef50_A6TSA3 Cluster: Amine oxidase; n=1; Alkaliphilus metall... 36 0.46
UniRef50_A3D4X7 Cluster: FAD dependent oxidoreductase; n=3; Shew... 36 0.46
UniRef50_A1SV61 Cluster: FAD dependent oxidoreductase precursor;... 36 0.46
UniRef50_Q6KCB6 Cluster: Dihydrolipoyl dehydrogenase; n=8; Plasm... 36 0.46
UniRef50_A7TI21 Cluster: Putative uncharacterized protein; n=1; ... 36 0.46
UniRef50_Q8RC01 Cluster: UDP-N-acetyl-D-mannosaminuronate dehydr... 36 0.61
UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 36 0.61
UniRef50_Q82W31 Cluster: Phosphoribosylaminoimidazole carboxylas... 36 0.61
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 36 0.61
UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3; Cl... 36 0.81
UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid aminot... 36 0.81
UniRef50_Q8GP50 Cluster: Eps11H; n=13; Lactobacillales|Rep: Eps1... 36 0.81
UniRef50_A6M0T5 Cluster: Amine oxidase; n=6; Clostridium|Rep: Am... 36 0.81
UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 36 0.81
UniRef50_A0UYP0 Cluster: Amine oxidase; n=1; Clostridium cellulo... 36 0.81
UniRef50_Q4J9Z6 Cluster: Conserved Crenarchaeal protein; n=3; Su... 36 0.81
UniRef50_Q8YKN8 Cluster: Zeta-carotene desaturase; n=4; Bacteria... 35 1.1
UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7; Bacte... 35 1.1
UniRef50_Q6MDA0 Cluster: Probable soluble pyridine nucleotide tr... 35 1.1
UniRef50_Q6FF29 Cluster: Putative oxidoreductase; putative flavo... 35 1.1
UniRef50_Q6A6B6 Cluster: Pyridine nucleotide-disulphide oxidored... 35 1.1
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 35 1.1
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;... 35 1.1
UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex,... 35 1.1
UniRef50_A7FX66 Cluster: Pyridine nucleotide-disulphide oxidored... 35 1.1
UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ac... 35 1.1
UniRef50_Q0CYI1 Cluster: Predicted protein; n=1; Aspergillus ter... 35 1.1
UniRef50_Q8TWI7 Cluster: UDP-N-acetylmuramoylalanine-D-glutamate... 35 1.1
UniRef50_Q9X0U4 Cluster: Glutamate synthase, beta subunit; n=5; ... 35 1.4
UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 35 1.4
UniRef50_Q3AEV2 Cluster: Prephenate dehydrogenase; n=1; Carboxyd... 35 1.4
UniRef50_Q2RJ81 Cluster: 4Fe-4S ferredoxin, iron-sulfur binding ... 35 1.4
UniRef50_Q2JD10 Cluster: Prephenate dehydrogenase; n=4; Frankia|... 35 1.4
UniRef50_Q1MF67 Cluster: Putative D-amino acid dehydrogenase pre... 35 1.4
UniRef50_Q99ZM2 Cluster: D-lactate dehydrogenase; n=7; Streptoco... 35 1.4
UniRef50_Q4FL01 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; B... 34 1.9
UniRef50_Q4FKW7 Cluster: D-amino-acid dehydrogenase small chain;... 34 1.9
UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1; Mycop... 34 1.9
UniRef50_Q2LWM5 Cluster: Zinc-binding dehydrogenase; n=1; Syntro... 34 1.9
UniRef50_Q1IUZ3 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 34 1.9
UniRef50_Q1IMR6 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 34 1.9
UniRef50_Q1FMM1 Cluster: Dihydrolipoyl dehydrogenase; n=2; Clost... 34 1.9
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 34 1.9
UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 34 1.9
UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;... 34 1.9
UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1; ... 34 1.9
UniRef50_A5V9L0 Cluster: FAD dependent oxidoreductase precursor;... 34 1.9
UniRef50_A7RTC7 Cluster: Predicted protein; n=1; Nematostella ve... 34 1.9
UniRef50_P12045 Cluster: Phosphoribosylaminoimidazole carboxylas... 34 1.9
UniRef50_UPI0001597852 Cluster: hypothetical protein RBAM_031240... 34 2.5
UniRef50_Q9JXF8 Cluster: Glycine oxidase ThiO; n=4; Neisseria|Re... 34 2.5
UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8; My... 34 2.5
UniRef50_Q8R9D9 Cluster: Dihydrolipoyl dehydrogenase; n=3; Therm... 34 2.5
UniRef50_Q8F125 Cluster: Cell-division inhibitor; n=3; Bacteria|... 34 2.5
UniRef50_Q39TK4 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 34 2.5
UniRef50_Q4AI87 Cluster: FAD-dependent pyridine nucleotide-disul... 34 2.5
UniRef50_Q2BN82 Cluster: D-amino acid dehydrogenase, small subun... 34 2.5
UniRef50_Q0F8T2 Cluster: Salicylate hydroxylase; n=1; alpha prot... 34 2.5
UniRef50_A4XMY3 Cluster: Prephenate dehydrogenase; n=1; Caldicel... 34 2.5
UniRef50_A0M4X2 Cluster: Kynurenine-3-monooxygenase-like protein... 34 2.5
UniRef50_Q8TZS4 Cluster: Glutamate synthase; n=78; cellular orga... 34 2.5
UniRef50_Q5ZV78 Cluster: Mercuric reductase; n=5; Legionella pne... 33 3.3
UniRef50_Q31JD0 Cluster: Thiamine biosynthesis oxidoreductase; n... 33 3.3
UniRef50_Q0C0V2 Cluster: Oxidoreductase, FAD-binding; n=2; Prote... 33 3.3
UniRef50_Q0B0P7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 33 3.3
UniRef50_A3EPX8 Cluster: Dihydrolipoyl dehydrogenase; n=1; Lepto... 33 3.3
UniRef50_Q02670 Cluster: ORF22; n=1; Podospora anserina|Rep: ORF... 33 3.3
UniRef50_A5UMG8 Cluster: Cell wall biosynthesis protein, MurD-li... 33 3.3
UniRef50_A3DNK1 Cluster: Dihydrolipoamide dehydrogenase; n=1; St... 33 3.3
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 33 4.3
UniRef50_Q8G3X6 Cluster: Possible class I pyridine nucleotide-di... 33 4.3
UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 33 4.3
UniRef50_Q87Q19 Cluster: D-amino acid dehydrogenase, small subun... 33 4.3
UniRef50_Q5H1Q2 Cluster: Putative uncharacterized protein; n=6; ... 33 4.3
UniRef50_Q5FJ98 Cluster: Peroxidase; n=8; Lactobacillales|Rep: P... 33 4.3
UniRef50_Q9JPB5 Cluster: Methoxyneurosporene dehydrogenase; n=5;... 33 4.3
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci... 33 4.3
UniRef50_Q1GNH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=7... 33 4.3
UniRef50_Q0AI36 Cluster: 3-hydroxybutyryl-CoA epimerase; n=3; Ni... 33 4.3
UniRef50_Q021A6 Cluster: FAD-dependent pyridine nucleotide-disul... 33 4.3
UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 33 4.3
UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 4.3
UniRef50_A6CF61 Cluster: Soluble pyridine nucleotide transhydrog... 33 4.3
UniRef50_A4CCE3 Cluster: Putative D-amino acid dehydrogenase, sm... 33 4.3
UniRef50_A4A0Z6 Cluster: Putative transmemembrane reductase oxid... 33 4.3
UniRef50_A1HBS6 Cluster: 2-polyprenyl-6-methoxyphenol hydroxylas... 33 4.3
UniRef50_A0YKN9 Cluster: Putative secreted oxidoreductase; n=1; ... 33 4.3
UniRef50_A0YDQ2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 33 4.3
UniRef50_Q5CRF9 Cluster: Alpha amylase; n=2; Cryptosporidium|Rep... 33 4.3
UniRef50_O28680 Cluster: Putative uncharacterized protein; n=1; ... 33 4.3
UniRef50_P77212 Cluster: Probable pyridine nucleotide-disulfide ... 33 4.3
UniRef50_Q9FC18 Cluster: 2,4-dienoyl-CoA reductase [NADPH]; n=5;... 33 5.7
UniRef50_Q92A98 Cluster: Lin2024 protein; n=13; Listeria|Rep: Li... 33 5.7
UniRef50_Q8ESA1 Cluster: Phosphoribosylaminoimidazole carboxylas... 33 5.7
UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus pla... 33 5.7
UniRef50_Q5WI78 Cluster: NADH peroxidase; n=1; Bacillus clausii ... 33 5.7
UniRef50_Q5L3D7 Cluster: Phosphoribosylaminoimidazole carboxylas... 33 5.7
UniRef50_P73059 Cluster: Mercuric reductase; n=11; Bacteria|Rep:... 33 5.7
UniRef50_Q222Q6 Cluster: FAD dependent oxidoreductase precursor;... 33 5.7
UniRef50_Q1YK26 Cluster: Phosphoribosylaminoimidazole carboxylas... 33 5.7
UniRef50_Q1Q5P1 Cluster: Similar to NAD(P) oxidoreductase, FAD-c... 33 5.7
UniRef50_Q1NYB6 Cluster: FAD-dependent pyridine nucleotide-disul... 33 5.7
UniRef50_A7DM30 Cluster: Multi-sensor hybrid histidine kinase; n... 33 5.7
UniRef50_A7B6H9 Cluster: Putative uncharacterized protein; n=1; ... 33 5.7
UniRef50_A6SY70 Cluster: Uncharacterized conserved protein; n=2;... 33 5.7
UniRef50_A5Z4N7 Cluster: Putative uncharacterized protein; n=1; ... 33 5.7
UniRef50_A3PFJ2 Cluster: NAD binding site:D-amino acid oxidase; ... 33 5.7
UniRef50_A7PXU5 Cluster: Chromosome chr15 scaffold_37, whole gen... 33 5.7
UniRef50_A7EL57 Cluster: Putative uncharacterized protein; n=1; ... 33 5.7
UniRef50_A4YI59 Cluster: Pyridine nucleotide-disulphide oxidored... 33 5.7
UniRef50_P54533 Cluster: Dihydrolipoyl dehydrogenase; n=41; Firm... 33 5.7
UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 33 5.7
UniRef50_UPI00015B56E9 Cluster: PREDICTED: similar to conserved ... 32 7.5
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 32 7.5
UniRef50_Q9PK36 Cluster: Putative uncharacterized protein; n=1; ... 32 7.5
UniRef50_Q98N90 Cluster: Mll0243 protein; n=1; Mesorhizobium lot... 32 7.5
UniRef50_Q97DR4 Cluster: NADH oxidase; n=1; Clostridium acetobut... 32 7.5
UniRef50_Q8XT97 Cluster: Putative type III effector protein; n=2... 32 7.5
UniRef50_Q8CX86 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ... 32 7.5
UniRef50_Q7UQS2 Cluster: Phosphoribosylaminoimidazole carboxylas... 32 7.5
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 32 7.5
UniRef50_Q6VXQ2 Cluster: NOXase; n=1; Enterococcus faecium|Rep: ... 32 7.5
UniRef50_Q3IBS8 Cluster: Iron-sulfur-binding protein, glutamate ... 32 7.5
UniRef50_Q18RI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 32 7.5
UniRef50_Q11MN5 Cluster: FAD dependent oxidoreductase; n=2; Meso... 32 7.5
UniRef50_Q11LC6 Cluster: FAD dependent oxidoreductase precursor;... 32 7.5
UniRef50_Q08VR6 Cluster: NADP oxidoreductase, coenzyme f420-depe... 32 7.5
UniRef50_Q03CK2 Cluster: Predicted dinucleotide-binding enzyme; ... 32 7.5
UniRef50_A7GZ57 Cluster: NADP oxidoreductase, coenzyme f420-depe... 32 7.5
UniRef50_A6NZT3 Cluster: Putative uncharacterized protein; n=2; ... 32 7.5
UniRef50_A5GED6 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 32 7.5
UniRef50_A5FR09 Cluster: FAD-dependent pyridine nucleotide-disul... 32 7.5
UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR... 32 7.5
UniRef50_A4M0G7 Cluster: 2-dehydropantoate 2-reductase precursor... 32 7.5
UniRef50_A3U8L8 Cluster: Putative uncharacterized protein; n=1; ... 32 7.5
UniRef50_A0LGG9 Cluster: FAD-dependent pyridine nucleotide-disul... 32 7.5
UniRef50_A0DJN2 Cluster: Chromosome undetermined scaffold_53, wh... 32 7.5
UniRef50_A4R025 Cluster: Putative uncharacterized protein; n=1; ... 32 7.5
UniRef50_Q8PXP4 Cluster: UDP-N-acetyl-D-mannosamine 6-dehydrogen... 32 7.5
UniRef50_Q64C49 Cluster: Formate dehydrogenase beta subunit; n=1... 32 7.5
UniRef50_Q6D8S1 Cluster: Nitric oxide reductase FlRd-NAD(+) redu... 32 7.5
UniRef50_O66913 Cluster: tRNA uridine 5-carboxymethylaminomethyl... 32 7.5
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 32 9.9
UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ... 32 9.9
UniRef50_UPI00006A011C Cluster: mucin 16 (MUC16), mRNA; n=3; Xen... 32 9.9
UniRef50_Q89ZR6 Cluster: NADPH-dependent glutamate synthase smal... 32 9.9
UniRef50_Q88YJ8 Cluster: NADH oxidase; n=8; Lactobacillaceae|Rep... 32 9.9
UniRef50_Q68VU4 Cluster: Dihydrolipoyl dehydrogenase; n=11; Rick... 32 9.9
UniRef50_Q8KRG4 Cluster: NADH oxidase; n=14; Bacteria|Rep: NADH ... 32 9.9
UniRef50_Q41B40 Cluster: Similar to Phytoene dehydrogenase and r... 32 9.9
UniRef50_Q1DAE6 Cluster: NADP oxidoreductase, coenzyme F420-depe... 32 9.9
UniRef50_Q11PG6 Cluster: Pyridine nucleotide-disulphide-related ... 32 9.9
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 32 9.9
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 32 9.9
UniRef50_Q090H7 Cluster: Soluble pyridine nucleotide transhydrog... 32 9.9
UniRef50_Q04KN1 Cluster: UDP-N-acetyl-D-mannosaminuronic acid de... 32 9.9
UniRef50_A7BS25 Cluster: Phosphoribosylaminoimidazole carboxylas... 32 9.9
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 32 9.9
UniRef50_A6GGV0 Cluster: Prephenate dehydrogenase; n=1; Plesiocy... 32 9.9
UniRef50_A4YNF9 Cluster: Oxidoreductase; (Flavoprotein subunit; ... 32 9.9
UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1; ... 32 9.9
UniRef50_A0Q826 Cluster: Dihydrolipoamide dehydrogenase; n=7; Fr... 32 9.9
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 32 9.9
UniRef50_A0DJ73 Cluster: Chromosome undetermined scaffold_52, wh... 32 9.9
UniRef50_Q8TJW5 Cluster: Putative uncharacterized protein; n=1; ... 32 9.9
UniRef50_A4YFQ3 Cluster: Pyridine nucleotide-disulphide oxidored... 32 9.9
UniRef50_P79076 Cluster: Pyranose 2-oxidase precursor; n=7; Agar... 32 9.9
UniRef50_Q6TGQ9 Cluster: L-amino-acid oxidase precursor; n=6; Sa... 32 9.9
>UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA -
Drosophila melanogaster (Fruit fly)
Length = 315
Score = 215 bits (525), Expect = 6e-55
Identities = 102/169 (60%), Positives = 125/169 (73%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 217
K+EKVGIVGSGLIGRSW+MLFASVGYQV L+D++ +Q++ A+ + +L+ LE GLLRG
Sbjct: 4 KNEKVGIVGSGLIGRSWSMLFASVGYQVVLYDILPEQVSTALTATQKELQDLEAKGLLRG 63
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
L A +QF C+ GT DL VK AIFVQEC+PE L+LKK +++ LD VV NTI
Sbjct: 64 KLTAAQQFACISGTNDLKELVKGAIFVQECIPERLDLKKALYKQLDAVVGPNTILSSSTS 123
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
++K+KA V+VSHPVNPPYYVPLVEIVPAPWTKPE KKTR
Sbjct: 124 TFLPSLFSADLKNKANVLVSHPVNPPYYVPLVEIVPAPWTKPEWVKKTR 172
>UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to
3-hydroxyacyl-coa dehyrogenase; n=5; Coelomata|Rep:
PREDICTED: similar to 3-hydroxyacyl-coa dehyrogenase -
Strongylocentrotus purpuratus
Length = 316
Score = 182 bits (443), Expect = 5e-45
Identities = 83/169 (49%), Positives = 113/169 (66%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 217
+S+K+GIVGSGLIGRSWAM+FAS G+ VT+FD+ Q+++A+ IK QL+ L + G+LRG
Sbjct: 2 ESQKIGIVGSGLIGRSWAMIFASAGFSVTIFDIEPSQVSNALKLIKSQLEELSESGMLRG 61
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
L+ + QF +KG+ + A+ A FVQECV E LE+K+KVF ++ V D I
Sbjct: 62 TLSVEAQFALIKGSNSMEEALAGASFVQECVFEKLEVKQKVFSEMEQYVSDGAILSSSSS 121
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
EN+K + Q I+SHP+NPPYY PLVEI+PAPWT +TR
Sbjct: 122 CIMPSQFTENLKRRNQCIISHPINPPYYAPLVEIIPAPWTDQSAIDRTR 170
>UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30;
Coelomata|Rep: Lambda-crystallin homolog - Homo sapiens
(Human)
Length = 319
Score = 171 bits (416), Expect = 9e-42
Identities = 79/164 (48%), Positives = 112/164 (68%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V IVGSG+IGRSWAMLFAS G+QV L+D+ ++QI +A+ +I+ ++K LE+ G L+G+L+
Sbjct: 9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSV 68
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
+EQ + G ++ AV+ A+ +QECVPE+LELKKK+F LD+++DD I
Sbjct: 69 EEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMP 128
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
+ H Q IV+HPVNPPYY+PLVE+VP P T P +T
Sbjct: 129 SKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRT 172
>UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 322
Score = 158 bits (383), Expect = 9e-38
Identities = 80/176 (45%), Positives = 108/176 (61%), Gaps = 3/176 (1%)
Frame = +2
Query: 23 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 202
M S + KV ++GSGLIGR+W+ LF+S GY V L+D V Q+ +A I QL+ LE
Sbjct: 1 MTSSTEKGKVAVIGSGLIGRAWSTLFSSAGYHVALYDTVSSQLVNAKEAIISQLQELESK 60
Query: 203 GLLRGN--LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDN- 373
LL+G A E F+ V T DL A+ +VQEC PENLELKKKVFQNL+ + +
Sbjct: 61 ELLKGRHCKTAQEAFKLVTTTDDLPQALNGVFYVQECTPENLELKKKVFQNLEATLSSSE 120
Query: 374 TIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
I E+++ + + IV+HP+NPPYYVPLVE++PAPWT V ++T
Sbjct: 121 VILASSTSCIMPSKFTESLQLRQRCIVAHPINPPYYVPLVEVIPAPWTDASVIEQT 176
>UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|Rep:
LOC570274 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 327
Score = 142 bits (344), Expect = 5e-33
Identities = 75/167 (44%), Positives = 104/167 (62%)
Frame = +2
Query: 29 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGL 208
S K + + +VGSGLIGRSWAM+F S GY+V L+D Q + AIA+I+ QL+ L++ +
Sbjct: 14 SSLKEKIITVVGSGLIGRSWAMVFLSGGYKVKLYDNKPGQASGAIAEIRKQLEELQQAKM 73
Query: 209 LRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 388
LRGNL+A EQ + DL A+ A FVQE V E+LE K+ VF ++ +V ++ I
Sbjct: 74 LRGNLSATEQLSRLSSHEDLQQALDGAFFVQESVFEDLEAKQSVFHAVEELVSESVILSS 133
Query: 389 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
++++ + IVSHPVNPPYYV LVE+VP P T P V
Sbjct: 134 STSCLMPSNVFSQVQNRTRCIVSHPVNPPYYVRLVELVPHPETLPAV 180
>UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Proteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Acidiphilium cryptum (strain JF-5)
Length = 312
Score = 123 bits (297), Expect = 2e-27
Identities = 62/166 (37%), Positives = 98/166 (59%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
K+ +VG+GL+G +WA++FA G+ V ++D VE AI I +LKTLE+ GL+
Sbjct: 2 KIAVVGAGLVGSAWAIVFARAGHDVAVYDAVEGGADRAIGLIGDRLKTLEEVGLIEDAAA 61
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
A ++ V+ LA AV DA ++QE V E +E K+++F LD VV T+
Sbjct: 62 AGQR---VRVAASLADAVADAAYIQESVFETVEQKRQIFAALDAVVGPETLIGSSSSGIP 118
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+++ + + +++HPVNPPY +P+VE+VPAPWT ++ R
Sbjct: 119 ASAFTDHVGCRERCLIAHPVNPPYLIPVVELVPAPWTAAATVQRVR 164
>UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5;
Alphaproteobacteria|Rep: Mll1034 protein - Rhizobium
loti (Mesorhizobium loti)
Length = 315
Score = 117 bits (281), Expect = 2e-25
Identities = 63/165 (38%), Positives = 90/165 (54%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V IVGSG IGR+WA+ FA G+ V ++D A I+ L L + LLRG +
Sbjct: 4 VAIVGSGFIGRAWAISFARAGHDVRMWDQSPAATGGARDYIEGVLGDLAANDLLRGQ-SV 62
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
D + DLA A+ DA VQE PENL++K++VF +D + TI
Sbjct: 63 DTVLGRIATVGDLAEALADAAHVQENTPENLDVKREVFSLIDRLAGPQTIIASSTSALLP 122
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
++++ + + +V HP+NPPY +P E+VPAPWT E +KTR
Sbjct: 123 SKFTDHLQGRHRCLVVHPINPPYLIPAAEVVPAPWTSAETLEKTR 167
>UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Oceanicola granulosus HTCC2516
Length = 312
Score = 116 bits (279), Expect = 4e-25
Identities = 66/166 (39%), Positives = 89/166 (53%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KV I+G+GLIG+SWA+ FA G VTL D A+A + L LE+ LL G
Sbjct: 3 KVAIIGAGLIGQSWAIAFARGGCAVTLHDRDHAVADRALAVLPDALAALERMDLLGGE-T 61
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
AD + DLA AV+ AI VQE PE LE+K+ VF LD+ D + +
Sbjct: 62 ADAVGARIDAASDLADAVRGAIHVQENTPETLEVKRSVFAQLDDAADADAVIASSSSALL 121
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ + A+ +V+HP+NPP+ VP VE+VP P T E +TR
Sbjct: 122 PSAFTDGLAGAARCLVAHPLNPPHLVPAVELVPGPQTSAETVARTR 167
>UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Pseudomonas putida W619
Length = 320
Score = 110 bits (265), Expect = 2e-23
Identities = 61/174 (35%), Positives = 96/174 (55%), Gaps = 1/174 (0%)
Frame = +2
Query: 11 LRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT 190
+R +S + + IVG+GLIGR+WA++FA G+ V L D+ + + ++ A I+ +L
Sbjct: 1 MRTTASSATERGPIAIVGAGLIGRAWAIVFARAGHPVRLHDMDLQTMQNSHAYIEARLNE 60
Query: 191 LEKDGLLR-GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVD 367
L + LL L + CV DLA A++D + VQE V E +E K +F +D +
Sbjct: 61 LAEFDLLNDAPLTVLARITCVP---DLADALRDVVLVQENVRETVEAKIDIFSRMDALAP 117
Query: 368 DNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ I +++ + + +V+HP NPPY VPLVE+ PAPWT+ EV
Sbjct: 118 KDAILASSTSWLPASEFTKDLPGRGRCVVAHPTNPPYLVPLVELCPAPWTESEV 171
>UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain
protein; n=1; uncultured bacterium 582|Rep:
3-hydroxyacyl-CoA dehydrogenase domain protein -
uncultured bacterium 582
Length = 322
Score = 107 bits (258), Expect = 1e-22
Identities = 59/162 (36%), Positives = 89/162 (54%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V +VG+GLIG WA++FA G+QVTL D+ ++ A + VQL+ LE+ L
Sbjct: 17 VSVVGAGLIGCGWAIVFARAGWQVTLQDIDLAKLQGAPKVLAVQLRMLEQHDLCADPAGI 76
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
+ + DL AV + +VQEC PE L LK+++F LD + TI
Sbjct: 77 LAR---ISYESDLKTAVCEVDYVQECGPEVLGLKQELFSELDALTPPETILASSTSGLMA 133
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
++ + + +V+HPVNPP+ VP+VEI P+ WT PE+ +
Sbjct: 134 SQFSAHLAGRHRALVAHPVNPPHLVPVVEISPSEWTDPEIVR 175
>UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 101 bits (243), Expect = 8e-21
Identities = 46/138 (33%), Positives = 80/138 (57%)
Frame = +2
Query: 125 LFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQE 304
++D+ EKQ+ A+ +++ L+ L++ GL RGNL+ADE V T L +K+AI++QE
Sbjct: 1 MYDISEKQLQVALENVEKNLRKLDEHGLQRGNLSADEALLRVSTTTSLNEVMKNAIYMQE 60
Query: 305 CVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYV 484
E+L + + ++ +D + D TI + + +K + ++ HPVNPP ++
Sbjct: 61 SALEDLNFRIQFYKVIDEIADPTTILASSTSTIPASKFTDGLINKERCLIVHPVNPPLFL 120
Query: 485 PLVEIVPAPWTKPEVTKK 538
PL E+VPAPWT + +
Sbjct: 121 PLTELVPAPWTSQDTVDR 138
>UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Paracoccus denitrificans (strain Pd 1222)
Length = 311
Score = 101 bits (241), Expect = 1e-20
Identities = 55/165 (33%), Positives = 85/165 (51%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+ IVG+GLIGR+WA +FA G+ V ++D+ + + DI + G + +
Sbjct: 4 IAIVGAGLIGRAWAFVFARAGFDVRVWDLDPQVLERLDGDIAAMVAQTAPFG--QAGADP 61
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
D ++ DLA A+ A VQE PE L +K+++F LD + I
Sbjct: 62 DATAARIRAVPDLAGALDGAELVQESGPEVLAIKRELFARLDGLAAAGVILASSSSALMA 121
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
E + ++ +V HPVNPP+ VP+VEI PAP+T P +T + R
Sbjct: 122 SAFAEGLPGASRCLVGHPVNPPHLVPVVEIAPAPFTDPVITARAR 166
>UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN
full-length enriched library, clone:A230106J09
product:crystallin, lamda 1, full insert sequence; n=3;
Euarchontoglires|Rep: Adult male hypothalamus cDNA,
RIKEN full-length enriched library, clone:A230106J09
product:crystallin, lamda 1, full insert sequence - Mus
musculus (Mouse)
Length = 140
Score = 96.7 bits (230), Expect = 3e-19
Identities = 44/85 (51%), Positives = 67/85 (78%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V IVGSGLIGRSWAMLFAS G++V L+D+ ++QITDA+ +I+ ++K+LE+ G L+G+L+A
Sbjct: 9 VVIVGSGLIGRSWAMLFASGGFKVKLYDIEQQQITDALENIRKEMKSLEQSGSLKGSLSA 68
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQE 304
+ Q + G +LA AV+ A+ +Q+
Sbjct: 69 ERQLSLISGCGNLAEAVEGAVHIQQ 93
>UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 -
Clostridium kluyveri DSM 555
Length = 319
Score = 96.7 bits (230), Expect = 3e-19
Identities = 51/158 (32%), Positives = 80/158 (50%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ V ++G+G +G L A G V +F + + IK LK LE+ G ++ N+
Sbjct: 4 KNVAVLGTGTMGNGIVQLCAESGLNVNMFGRTDASLERGFTSIKTSLKNLEEKGKIKTNI 63
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ E + +KG + AV+ FV EC+ E+LELK++VF LD + I
Sbjct: 64 SK-EILKRIKGVKTIEEAVEGVDFVIECIAEDLELKQEVFSKLDEICAPEVILASNTSGL 122
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
N KH +V+++H NPP ++PLVE+VP T
Sbjct: 123 SPTDIAINTKHPERVVIAHFWNPPQFIPLVEVVPGKHT 160
>UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 330
Score = 96.7 bits (230), Expect = 3e-19
Identities = 63/173 (36%), Positives = 95/173 (54%), Gaps = 8/173 (4%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLLRG 217
KV I+G G IG SWA LF + G +V+ FDV E + + +A+ L +L GL++
Sbjct: 6 KVAIIGCGSIGASWAALFLAQGLEVSAFDVNPSAESFLRELVANALPVLSSL---GLVKS 62
Query: 218 N--LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 391
+ AD +F T D+A A+K+A FVQE PE L+ K+K+F+ + N+VD +TI
Sbjct: 63 SQATAADIEF-----TTDMATALKNASFVQENGPERLDFKQKLFRGVANLVDPDTIIATS 117
Query: 392 XXXXXXXXXXENM--KHKAQ-VIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
+ + +HK + V+V HP NPP+ +PLVE+V T +T
Sbjct: 118 SSGLTCSSIQQGLEAQHKPERVVVGHPFNPPHLIPLVEVVGGEQTSQATISRT 170
>UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 315
Score = 92.3 bits (219), Expect = 7e-18
Identities = 56/167 (33%), Positives = 84/167 (50%), Gaps = 2/167 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KV +G+G +G SWA LFA G V ++D + + A A I + TL + + G+ +
Sbjct: 4 KVACIGAGTVGASWASLFAWRGCDVAVYDPFPEALNRAEASIARTVSTLSE--IFSGSED 61
Query: 227 -ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
VK T +L A+K A +VQE E LE+K+ +F+ +D + + TI
Sbjct: 62 DVKSALSRVKFTENLEEALKGAYYVQESAVEKLEVKRDLFEKMDAIAEPETILATSTSGL 121
Query: 404 XXXXXXENM-KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
KH + I +HP NPP+ +PLVE+VP T T+KT
Sbjct: 122 SISEIQTAARKHPERCITAHPYNPPHLIPLVEVVPRKQTDESCTEKT 168
>UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=3; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 318
Score = 91.9 bits (218), Expect = 9e-18
Identities = 51/156 (32%), Positives = 87/156 (55%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+ IVG+G IG ++A+LFAS G V ++D + A +++ +L+ L K L +
Sbjct: 13 ISIVGAGSIGVAFAVLFASRGASVRIWDALPDAFDRAANELRSRLEMLAKASAL--SEPP 70
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
DE + +LA A+ A VQEC PEN++LK +F+ L ++ D+ +
Sbjct: 71 DEISSRISWHRNLAEALDGADLVQECAPENIDLKVDLFRWLADLTPDHVVLASSSSALIA 130
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
+++ + +V+V HP NPPY +P++E+VP+P T
Sbjct: 131 SLIAPDIEIRRRVLVGHPGNPPYLIPVIEVVPSPET 166
>UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Roseovarius sp. HTCC2601
Length = 316
Score = 89.4 bits (212), Expect = 5e-17
Identities = 49/165 (29%), Positives = 84/165 (50%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
K+ I+GSG+IG SWA+++A G V +++ E A+ ++ L + LLR
Sbjct: 5 KIAILGSGVIGASWAIVYARSGCDVAIYERSEAFRDSAMQRLESSLAS--SASLLRDGET 62
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
+ + L AV A FV EC+ ENL+ K+++F L++ + I
Sbjct: 63 VQDVLARITLHDTLEAAVAGADFVHECIVENLDSKRQIFAALNDAAEPEAILASTTSSFP 122
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
++ + + I+ HP PP+ +P+ EI PAP+T EV+++T
Sbjct: 123 VSHFASDLACRDRCIIVHPATPPHLLPVTEICPAPFTSAEVSERT 167
>UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Planctomyces maris DSM 8797
Length = 311
Score = 89.0 bits (211), Expect = 6e-17
Identities = 52/170 (30%), Positives = 86/170 (50%), Gaps = 3/170 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ-LKTLEKDGLL--R 214
+++GI+G+GLIG SWA FA+ G +V +FD V + ++ VQ L+ L L+ +
Sbjct: 2 QEIGILGAGLIGASWATFFAAQGLRVRIFD-VNNTVKQQAQELSVQNLQRLADLELISRK 60
Query: 215 GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
A+E+ V +L + D +VQE V E+ E+K V+Q + + I
Sbjct: 61 DAATAEEKLNVVDSLAEL---LTDVEYVQESVIEDYEIKADVYQQFEQYAPEAAILGSSS 117
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
M+H + +++HP NPP+ +PLVE+VP T E + +
Sbjct: 118 SGLLMTRMQTVMQHPGRALIAHPFNPPHLIPLVELVPGEQTATETMETVK 167
>UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Roseobacter denitrificans OCh 114|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Roseobacter
denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 331
Score = 88.6 bits (210), Expect = 8e-17
Identities = 49/160 (30%), Positives = 82/160 (51%), Gaps = 4/160 (2%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V I+G GLIG++WA +F G +VTL+D + A A + ++ R +L
Sbjct: 19 VAIIGCGLIGQAWATVFLRAGMRVTLYDAASGLVEQAKAQVIERMTEFA-----RFDLVT 73
Query: 230 DEQFQCVKGTCDLAIAVKDAI----FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
E + +LA ++DA+ ++QE E L++K ++ + +D + +
Sbjct: 74 HETLERAPAHIELADTLEDAVSAADYIQESGSEALDVKIELTREIDRFAAPHVVIGSSTS 133
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
E +K + + +V HP+NPP+ VPLVE+VPAPWT
Sbjct: 134 GITASRYSETIKGRERCLVVHPINPPHLVPLVEVVPAPWT 173
>UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=3; Bordetella|Rep: Putative 3-hydroxyacyl-CoA
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 313
Score = 86.2 bits (204), Expect = 4e-16
Identities = 53/162 (32%), Positives = 83/162 (51%), Gaps = 2/162 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK-TLEKDGLLRGNLN 226
V ++G G+IG SWA++FA G +VT +VE+ +A + +L +E+ L G
Sbjct: 4 VAVIGGGIIGASWAVVFARRGLEVT---IVERDAA-CLAGLPARLAGMIERSASLLGAGE 59
Query: 227 ADEQFQCVKGTCD-LAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
G D LA AV A +VQE V ENL LK+ +F LD + + +
Sbjct: 60 QPGDVAARIGATDALAAAVGRADYVQEAVSENLALKRTLFAELDALAPAHALLASSTSTY 119
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
E + +A+ +V+HP+ PP+ P+VE+ + WT P+V
Sbjct: 120 GASQFTEALAGRARCLVAHPMTPPHLSPVVEMAASAWTDPQV 161
>UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 311
Score = 84.2 bits (199), Expect = 2e-15
Identities = 57/166 (34%), Positives = 86/166 (51%), Gaps = 2/166 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK-TLEKDGLLRGNL 223
KV I+G+G+IG +WA F + G+ VT FD + A A ++ Q++ LE G G++
Sbjct: 6 KVAILGTGVIGAAWATGFLTAGHTVTAFDPAD----GAEARLRSQVEGNLEVTG--EGDI 59
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ + G+ LA +V DA FVQE PE L++K+ + D+ V + I
Sbjct: 60 TSAMERLHFAGS--LAESVGDADFVQENGPERLDIKQSMLAETDSAVPASAIIASSTSGF 117
Query: 404 XXXXXXENM-KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
H +++V HP NP + VPLVE+VP P T EV K+
Sbjct: 118 APSELATKATNHPERIVVGHPFNPAHLVPLVELVPTPATPAEVVKR 163
>UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Rhodobacterales bacterium HTCC2654
Length = 324
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/167 (29%), Positives = 83/167 (49%), Gaps = 1/167 (0%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITD-AIADIKVQLKTLEKDGLLRGNL 223
+V +G G +G WA +FA G++V L+D I A+ I+ L+ L ++ + G
Sbjct: 3 RVVCIGVGTVGCGWATVFARAGHEVVLYDADADAIAARALPRIEATLEQLGRE-MPTGET 61
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
AD + + ++ L A+ A VQE V E+L +K+ +F + D+ +
Sbjct: 62 PADIRAR-IRVAGSLEEALSGAEVVQESVREDLAIKRALFDEIGAAAPDDCLLLSSTSAL 120
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
++ H + +V HPVNPP ++PLVE+ P T PE ++ R
Sbjct: 121 PGSQFLSDIPHPERALVGHPVNPPSHIPLVELCATPLTAPETVERAR 167
>UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyacyl-CoA-dehydrogenase -
Sulfolobus solfataricus
Length = 324
Score = 83.8 bits (198), Expect = 2e-15
Identities = 48/167 (28%), Positives = 82/167 (49%), Gaps = 1/167 (0%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KV ++G+G+IG W L + GY+V L+ ++ + A+A + L L+ G++ N
Sbjct: 10 KVAVIGAGVIGVGWTTLLLAKGYKVNLYTEKKETLEKALAKVSAYLVNLKNLGMI--NEE 67
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
+ + G + A+ + FV E + E+ KK +F+ LD + + I
Sbjct: 68 PESYITNLTGITKIDDAIHNVDFVIEAIIEDYTAKKNLFKLLDTQLPQDIIIASSTSGLL 127
Query: 407 XXXXXENM-KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ M +H + +++HP NPP+ +PLVEIVP T E TR
Sbjct: 128 MTEIQKAMIRHPERGVIAHPWNPPHLLPLVEIVPGEKTSKETVDLTR 174
>UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=16; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Silicibacter pomeroyi
Length = 487
Score = 83.0 bits (196), Expect = 4e-15
Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 4/167 (2%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLL-RGNL 223
I+G G+IG WA F G+ V +FD E++I + +A+ + L L L G L
Sbjct: 6 IIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGEVLANARRSLPGLSDMPLPPEGKL 65
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ DL AV A ++QE VPE L+LK KV++++ D I
Sbjct: 66 SFH---------ADLGEAVTGAAWIQESVPERLDLKLKVYRSIQEACDPGAILGSSTSGF 116
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
E Q++V+HP NP Y +PL+E+V P PE+ ++ +
Sbjct: 117 KPSELQEGALRPGQIVVTHPFNPVYLLPLIELVTTPENSPEMIERAK 163
>UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Archaea|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Thermoplasma volcanium
Length = 659
Score = 82.6 bits (195), Expect = 5e-15
Identities = 51/161 (31%), Positives = 77/161 (47%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KV ++GSG++G A A GY V L D+ + + A A+I L L K G L
Sbjct: 5 KVTVIGSGIMGHGIAETIALAGYDVNLEDISDDVLAKAKAEIDASLDRLVKSGKLSDKTK 64
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
+ + +VKDA V E VPE L++K++VF LD ++ I
Sbjct: 65 VLGRIHYFTSIPE---SVKDADLVIEAVPEILDIKRQVFAQLDQSTKEDAILATNTSNIR 121
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
E +K K +V+ H NPP + LVE++ + +T+ EV
Sbjct: 122 LTEIAEGVKKKGKVVGMHFFNPPVVLKLVEVIRSDYTEDEV 162
>UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2;
Bifidobacterium longum|Rep: Possible butyryl-CoA
dehydrogenase - Bifidobacterium longum
Length = 319
Score = 80.2 bits (189), Expect = 3e-14
Identities = 49/161 (30%), Positives = 73/161 (45%)
Frame = +2
Query: 59 VGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADEQ 238
VG+G +G + + FA GY V L E + A+ I+ + + GLL+ D
Sbjct: 14 VGTGTMGHAITLQFALAGYPVHLVGRSEASLEKAMKAIRSDAEDFAEAGLLKAGDTVDTV 73
Query: 239 FQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXX 418
+ G D A V D FV E V ENL++KK V+ +++ + I
Sbjct: 74 LARITGYADYASGVADVDFVIESVAENLDVKKSVWTEVEHAAPKDAILSTNTSGLSPTAL 133
Query: 419 XENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
M H + +V+H NP +PLVE+VP T P+V T
Sbjct: 134 QSVMGHPERFVVAHFWNPAQLMPLVEVVPGEKTDPKVVDIT 174
>UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6;
Bacillaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 287
Score = 80.2 bits (189), Expect = 3e-14
Identities = 53/167 (31%), Positives = 85/167 (50%), Gaps = 3/167 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
E++ +VGSG++GR A + A G+Q TL D+ ++Q+ A + ++ ++ + G+ RG L
Sbjct: 3 ERLVVVGSGVMGRGIAYVGAVGGFQTTLVDIKQEQLESA----QKEIASIFEQGVARGKL 58
Query: 224 NADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
E+ + + + DLA AV+DA V E VPE LELKK+VF+ +D +
Sbjct: 59 TDSERQEAEARLSYSLDLAAAVRDADLVIEAVPEKLELKKQVFETIDAHAPASCYFATNT 118
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
K +VI H NP + + LVEI+ T E +
Sbjct: 119 STMSPTEIGSFTKRPERVIAMHFFNPVHKMKLVEIIRGLETSDETAQ 165
>UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Burkholderia sp. 383|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 333
Score = 79.8 bits (188), Expect = 4e-14
Identities = 50/162 (30%), Positives = 79/162 (48%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
E VGI+G+G IG SWA LF + G +V ++D + ++ +LE+ GL R
Sbjct: 12 EVVGILGAGTIGASWAALFLAAGLEVDVYDPSPEGEAFVRDYVRHAWPSLERLGLARRGD 71
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+F AV A FVQE VPE +E+K +++ +++ +D I
Sbjct: 72 PGRLRFVATPEE-----AVARAQFVQESVPERIEIKHALYRRIEDHLDPRAIVCSSASGL 126
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
K+ + I+ HP NPP+ +PLVE++ T+P V
Sbjct: 127 LVKEMQAGWKNPGRFILGHPFNPPHLIPLVELLGNEKTEPGV 168
>UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=17; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Silicibacter sp. (strain
TM1040)
Length = 491
Score = 79.8 bits (188), Expect = 4e-14
Identities = 53/172 (30%), Positives = 82/172 (47%), Gaps = 4/172 (2%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLL 211
++ I+G G+IG WA F G+ V +FD E++I D +A+ + L L L
Sbjct: 2 TKTAAIIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGDVLANARRSLPGLGNVALP 61
Query: 212 -RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 388
G+L+ E LA V+ +VQE VPE L+LK+KV+ L+ +
Sbjct: 62 PEGSLSYHET---------LAETVQGVDWVQESVPERLDLKQKVYAELEAHAPGGAVIGS 112
Query: 389 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ + AQ++V+HP NP Y +PLVE+V PE+ K +
Sbjct: 113 STSGYKPSQLQDGFTNAAQIVVAHPFNPVYLMPLVEVVTTDVNTPEMIAKAK 164
>UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 668
Score = 79.8 bits (188), Expect = 4e-14
Identities = 50/160 (31%), Positives = 80/160 (50%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V ++G+GL+G A + A GY VT+ D+ ++ + + IK L LE+ G ++ +A
Sbjct: 20 VAVLGAGLMGHGIAEVCAMAGYNVTMRDIKQEFVDRGMNMIKESLAKLEQKGKIK---SA 76
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
+E +K T DL AVKDA V E VPE +E+KK+V++ +D + + I
Sbjct: 77 EEVLSRIKPTVDLEEAVKDADLVIEAVPEVVEIKKQVWEEVDKLAKPDCIFTSNTSTMRI 136
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ + H NPP + LVE++ T EV
Sbjct: 137 TMLADFTSRPEKFAGLHFFNPPVLMRLVEVIRGEKTSDEV 176
>UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 314
Score = 79.0 bits (186), Expect = 7e-14
Identities = 51/169 (30%), Positives = 84/169 (49%), Gaps = 6/169 (3%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V ++G+G IGRS+A LFA GY V +FD + + + +++ ++ + A
Sbjct: 5 VAVIGAGTIGRSFAWLFARSGYPVQVFDP-RPDLAEVVTELQAEVSA---------DAAA 54
Query: 230 DEQFQCVKGTCDLAIAVKDAI----FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
+ GT LA +V+ A+ FVQE PE+ + K K+F + + I
Sbjct: 55 HDMLASELGTISLAESVETAVAGASFVQESGPEDPQAKPKLFAQIAAAAPKDAIFATSSS 114
Query: 398 XXXXXXXXENMKHK--AQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
++ + A+VIV HP NPP+ +PLVE+VPAP T + ++
Sbjct: 115 TIPASLIARHLPPEVAARVIVGHPFNPPHLMPLVEVVPAPATSSDTVER 163
>UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Bacillus sp. SG-1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bacillus sp. SG-1
Length = 293
Score = 79.0 bits (186), Expect = 7e-14
Identities = 52/167 (31%), Positives = 84/167 (50%), Gaps = 3/167 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+K+ ++GSG++GR A + A G+Q TL DV ++Q+ A + +L ++ + G+ RG L
Sbjct: 13 DKLVVIGSGVMGRGIAYVSAVGGFQTTLVDVEQRQLDSA----QGELTSIFQKGVDRGKL 68
Query: 224 NADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
+ +E + + D+A AV+ A V E VPE E+KK VF+ +D ++
Sbjct: 69 SKEESTDAQGRLSFSTDMAKAVESADLVIEAVPEKTEIKKAVFEKIDEYAQESCYFATNT 128
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
+VI H NP + +PLVEIV T E T+
Sbjct: 129 STMSPTEIASFTGRPKKVIAMHFFNPVHKMPLVEIVRGLETSDETTQ 175
>UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Sulfolobus|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Sulfolobus solfataricus
Length = 384
Score = 78.2 bits (184), Expect = 1e-13
Identities = 49/166 (29%), Positives = 83/166 (50%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+K+G+VG+G +G A + A Y V++ D+ + A I L + G ++
Sbjct: 4 KKIGVVGAGTMGHGIAEVSALANYNVSVVDISWDFLNRAKERIMESLNKFYEKGQIKEK- 62
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
++ + ++ + + ++DA FV E VPE +ELK+KVF+ LD++ +T
Sbjct: 63 -PEDIMKRIEFSTSYDV-MRDADFVIEAVPEIIELKRKVFETLDSITPSHTFLASNTSSI 120
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
E K K ++I H NPP + LVEIVP+ +T E + T
Sbjct: 121 PISTIAEVTKRKEKIIGMHFFNPPPIMKLVEIVPSKYTSDETIEVT 166
>UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 281
Score = 77.8 bits (183), Expect = 2e-13
Identities = 53/168 (31%), Positives = 74/168 (44%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 220
+E + ++G+G++G A A VG V L+DV E + + +A + L+ K G L
Sbjct: 2 AETIAVIGAGVMGSGIAQTAAMVGKTVYLYDVSEAALQNGLASAEKSLRRFVKTGGL-SE 60
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
A ++ T DLA AV+ A V E VPENL LKK VFQ LD + + I
Sbjct: 61 PEARAALGRIRSTVDLAEAVRGADVVIEAVPENLALKKDVFQQLDQLAKPDAILATNTSE 120
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
VI H NP + L+EIV T + R
Sbjct: 121 LSVTALAAATNRPENVIGMHWFNPAPVMKLIEIVKGETTSDDTVDAIR 168
>UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=3; Staphylococcus|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 321
Score = 77.8 bits (183), Expect = 2e-13
Identities = 52/164 (31%), Positives = 73/164 (44%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
K +VG+G+IG W + G++V D E + +K E+ GL N
Sbjct: 2 KFAVVGTGVIGSGWITRMLAHGHEVIATDPSEGAYERMLTQVKQNWPYAEQMGLAE---N 58
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
A Q + T L AVKDA +QE VPE E+K V + +D
Sbjct: 59 AS--IQNLTFTPHLEEAVKDADHIQENVPEVEEIKDAVLKEIDFYAKPEATIGSSTSGIM 116
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
N+ H +++V+HP +P Y +PLVEIVP T E T K
Sbjct: 117 PSELQANLSHPERLVVAHPFHPVYILPLVEIVPGKQTSEETTVK 160
>UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;
n=3; Rhodobacteraceae|Rep: Putative hydroxlacyl-CoA
dehydrogenase - Sulfitobacter sp. NAS-14.1
Length = 309
Score = 77.4 bits (182), Expect = 2e-13
Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLLRGN 220
V ++G GLIG SWA LF G+ V +D +A QL+ + +G
Sbjct: 7 VAVIGCGLIGASWAALFQHAGHTVRAWDPDTGARDGFAARVAGPLAQLQEISAGAAPQGA 66
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
L+ E Q A++D + +QE PEN+ LK +++ ++++V + I
Sbjct: 67 LSTHESLQD---------ALQDVVLIQENAPENVPLKHQLYAQIESIVAPDVIIASSTSA 117
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEI 499
M+H ++I +HP NPP+ VPLVE+
Sbjct: 118 HPWSDLVPGMQHPDRLITAHPFNPPHLVPLVEV 150
>UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=2; Thermoplasmatales|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Thermoplasma acidophilum
Length = 291
Score = 77.4 bits (182), Expect = 2e-13
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 3/160 (1%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK---VQLKTLEKDGLLRGNLN 226
+VGSG++G+ A +FA GY VT+ DV + + +A+ IK L L K G + +
Sbjct: 8 VVGSGVMGQGIAQVFARSGYPVTIIDVRDDILANAVRSIKEGRYGLMNLVKKGTMTES-E 66
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
D+ ++ + ++ DA V E VPENL+LK+KVF +++ V +N I
Sbjct: 67 VDKIMGKIRTSTSYG-SLSDADIVVEAVPENLDLKRKVFIDIEKNVSENAIIASNTSGIT 125
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+++K K + I H NP + L+E+V A T +
Sbjct: 126 IAEIAQDLKKKDRAIGMHWFNPAGIMKLIEVVRAKMTSED 165
>UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=5; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Silicibacter pomeroyi
Length = 317
Score = 76.6 bits (180), Expect = 4e-13
Identities = 53/162 (32%), Positives = 73/162 (45%), Gaps = 3/162 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVT--LFDVVEKQITDAIADIK-VQLKTLEKDGLLRG 217
+V +G G IG WA F + GY VT L D E+ I D + L L GL G
Sbjct: 11 RVTSIGGGPIGGGWAAHFLARGYDVTSYLHDRAEEGAFRTILDTAWISLTAL---GLAPG 67
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
++ DL AV A F+QE PENL +K+ ++ L +V +N +
Sbjct: 68 -----ASLDRLRVVHDLDAAVAGAGFIQESAPENLAMKQALYHRLGRIVPENVVIGSSTS 122
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKP 523
N + + ++ HP NPPY +PLVEIV T P
Sbjct: 123 GLMMTDIQANCETPGRTVIGHPFNPPYLLPLVEIVGGERTDP 164
>UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1;
Brevibacterium sp. HCU|Rep: Hydroxyacyl-CoA
dehydrogenase - Brevibacterium sp. HCU
Length = 316
Score = 75.8 bits (178), Expect = 6e-13
Identities = 49/160 (30%), Positives = 80/160 (50%), Gaps = 1/160 (0%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
VGI G+G IG ++A+LFA G+ V +FD + + I ++ L++ LL N
Sbjct: 7 VGIFGAGSIGTAFALLFADAGFAVRIFDPDPSALERSRHVIDQRITELQRFTLLAS--NP 64
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
E + ++ A AI VQE PE+++ K+ +F++L V D TI
Sbjct: 65 SEVRELIEIVSSARTAASGAILVQEAGPEDVQTKQHIFEDLTAVTSDETILASASSAIPS 124
Query: 410 XXXXENMKHKA-QVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+ H A + ++ HP NPPY + +VE+V P T+ +
Sbjct: 125 SRFVD--VHSAFRSLIGHPGNPPYLLRVVELVGNPSTEEQ 162
>UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 661
Score = 75.8 bits (178), Expect = 6e-13
Identities = 49/162 (30%), Positives = 78/162 (48%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V ++G+G +G + A + A G+ V L DV E Q+ A+ I+ L+ + G + + +
Sbjct: 9 VAVIGAGSMGHAIAEVVAIHGFNVKLMDVSEDQLKRAMEKIEEGLRKSYERGYI--SEDP 66
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
++ + ++ T DL KDA V E +PE +LKKKVF ++ D+TI
Sbjct: 67 EKVLKRIEATADLIEVAKDADLVIEAIPEIFDLKKKVFSEIEQYCPDHTIFATNTSSLSI 126
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
E K + I H NPP + L+EIV T E +
Sbjct: 127 TKLAEATKRPEKFIGMHFFNPPKILKLLEIVWGEKTSEETIR 168
>UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 323
Score = 74.9 bits (176), Expect = 1e-12
Identities = 51/164 (31%), Positives = 75/164 (45%), Gaps = 4/164 (2%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGL-LR 214
+V ++G+G IG W LF + GY+V + +E I DA+ L +D L
Sbjct: 11 RVAVIGAGSIGLGWITLFLAHGYRVRVNSTRSNIETVIHDALRLFTPGLPGASRDPADLA 70
Query: 215 GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
G L + DL AV D VQE PENLE+K+ +F L+ T+
Sbjct: 71 GRLEIEP---------DLERAVADVAVVQENTPENLEIKQDLFARLEKHAAAGTLLLSST 121
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
M + + +IV HP NPP+ +PLVE+V + P+
Sbjct: 122 STMLPADLGARMDNPSHLIVGHPFNPPHVIPLVEVVGDTTSDPD 165
>UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG00090.1 - Gibberella zeae PH-1
Length = 320
Score = 74.5 bits (175), Expect = 1e-12
Identities = 50/161 (31%), Positives = 76/161 (47%), Gaps = 1/161 (0%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V IVG G+IG WA+LF S G +V + D + A +K L+ RGN
Sbjct: 8 VAIVGCGVIGMGWAVLFMSCGLKVIISDPAD----GAHESLKRYLEQARSFFEERGNF-- 61
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLD-NVVDDNTIXXXXXXXXX 406
D+ + D+ + + FVQE PE +E K+ + + LD N I
Sbjct: 62 DKLSSNYEFVDDILPLLPEVDFVQENGPERVEFKQSLMEKLDENTRPGVAIASSSSGLPS 121
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ K +++++ HP NPP+ +PLVE+VP P T +V
Sbjct: 122 SAFIQKCKKDPSRILIGHPFNPPHLIPLVEVVPHPGTSSDV 162
>UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=1; Treponema denticola|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Treponema denticola
Length = 309
Score = 73.3 bits (172), Expect = 3e-12
Identities = 48/165 (29%), Positives = 81/165 (49%)
Frame = +2
Query: 23 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 202
M K K KV +VG G +G + +FA G+ V + + + + A+ IK+ L +
Sbjct: 1 MIEKGKKIKVAVVGDGTMGHGISEVFAKAGHTVQIIGLNDASLKSALDRIKLSLNEFVAE 60
Query: 203 GLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIX 382
GL+ + + D + + D+ A +DA V E +PEN++LK + F L+ + +TI
Sbjct: 61 GLVSAS-DIDTIVGRISFSTDIQKA-EDAAIVIEALPENMDLKTETFGKLEKICPQDTIL 118
Query: 383 XXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
+ +K + +VI +H PP +PLVE+ AP T
Sbjct: 119 ATASGHSVSEVIAQ-VKKRDRVIATHFWFPPQLLPLVEVCGAPET 162
>UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 317
Score = 73.3 bits (172), Expect = 3e-12
Identities = 51/166 (30%), Positives = 74/166 (44%), Gaps = 1/166 (0%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
++V ++G+G+IG SWA LF + G V DV + LE+ GL
Sbjct: 6 KRVAVIGTGVIGASWAALFLAKGLDVAATDVAPDAEARLRQYLDAAWPALEELGLAPAAS 65
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVD-DNTIXXXXXXX 400
A F T DLA AV A VQE PE ++ K+ ++ LD ++ D I
Sbjct: 66 RARLTF-----THDLAEAVAGAGLVQENGPERIDFKRTLYGQLDALLPPDVPIASSSSGL 120
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
H + ++ HP NPP+ +PLVEIV T + +K
Sbjct: 121 TMSEIQTGCPAHPERCVIGHPFNPPHLIPLVEIVSGAQTSEQTVEK 166
>UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a; n=3;
Magnetospirillum|Rep: Glyoxysomal fatty acid
beta-oxidation multifunctional protein MFP-a -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 703
Score = 73.3 bits (172), Expect = 3e-12
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 3/164 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KVGI+G+G +G AM FA++G VT+ DV ++ + + I+ K E+ + RG+L
Sbjct: 296 KVGIIGAGTMGGGIAMCFANIGIPVTIIDVSDENLQRGLGVIR---KNYERS-VSRGSLT 351
Query: 227 ADE---QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
++ + + + D A A+KDA E V E +ELKK +F LD V+ I
Sbjct: 352 QEQLESRMGLLSASTDYA-ALKDADLAIEAVFEKMELKKDIFAKLDAVLPAGAILGTNTS 410
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
K A VI H +P +PL+EIV T +V
Sbjct: 411 TLDIDEIANTTKRPADVIGLHFFSPANVMPLLEIVQGKQTAMDV 454
>UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 313
Score = 72.9 bits (171), Expect = 4e-12
Identities = 48/170 (28%), Positives = 80/170 (47%)
Frame = +2
Query: 35 FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLR 214
F++ K+ +VG+G++G A L+A G+QV L+D +Q+ A I ++ L K+GL
Sbjct: 2 FENWKLLVVGAGVMGSGIAQLYACKGFQVALYDKFPEQLDRAKQLIANNMENLIKEGLAT 61
Query: 215 GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
A+ + +L A V E V EN ++K++ F LD + + I
Sbjct: 62 QE-EAERTKTLISYETELEKCAPQADLVLESVFENADVKRETFAQLDKLCASDCILCSNT 120
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ H + I++H NPP+ + LVE+V P T E K +
Sbjct: 121 SASNIFEIAP-VSHPERQIITHYFNPPFIMDLVEVVMGPKTSDETLDKVK 169
>UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24;
Burkholderia|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 305
Score = 72.5 bits (170), Expect = 6e-12
Identities = 48/167 (28%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
++ IVG+G+IG SWA + + G+ V D + AD +++ G L+
Sbjct: 5 RIAIVGAGVIGASWAAFYLTQGFDVVATDPAPQ------ADTRLRESLAAFLGERAAELS 58
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNT-IXXXXXXXX 403
A F DL A+ FVQE PE L+LK+ +++ +D+V+ + I
Sbjct: 59 ARLSFDA-----DLVRALDGVDFVQENGPERLDLKRALYRQMDDVLPAHVPIASSSSGLK 113
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
KH + +++HP NPP+ +PLVE+V T +VT + +
Sbjct: 114 MSDIQTACDKHPERCLIAHPFNPPHLIPLVELVGGDATSQDVTARVK 160
>UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Marinomonas sp. MED121|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Marinomonas sp. MED121
Length = 323
Score = 72.1 bits (169), Expect = 8e-12
Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 1/166 (0%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KVG++G+G+IG +WA+ + +G +V +D + + T+EK GL G
Sbjct: 12 KVGVIGTGVIGGAWALHYLRMGMEVVAYDPGPNSKEKLLTMVDNIWPTIEKLGLREG--A 69
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVD-DNTIXXXXXXXX 403
+ ++ + V LA V+ +QE PE L+ K+ +F +LD +V D I
Sbjct: 70 SKDKLRFVDSLDALANQVE---VIQESTPERLDAKRSLFADLDCIVPADVVIISSTSGFA 126
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
E + +V HP NPPY VP E+ T EV T
Sbjct: 127 MTDMANELETQPDRFVVGHPFNPPYLVPFCEVCGGERTSQEVVDWT 172
>UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Archaea|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Sulfolobus acidocaldarius
Length = 657
Score = 71.3 bits (167), Expect = 1e-11
Identities = 49/165 (29%), Positives = 75/165 (45%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+VG+VG+G +G A + A G+ V L DV E + +A+ I+ L+ L + ++ N N
Sbjct: 6 RVGVVGAGTMGHGIAEVVAIAGFNVVLTDVNEDILRNALEKIRWSLEKLREKRQIKENPN 65
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
+K T D F+ E E ++K+K+F LD VV + I
Sbjct: 66 T--VLSRIKTTVSFG-DFSDVDFIIEAAIERSDVKRKIFSELDRVVKKDAIFATNTSTIP 122
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
E + + I H +NPP +PLVEI+ T E K T
Sbjct: 123 ISYLAEVTGRQEKFIGLHFMNPPVLMPLVEIIMGNKTAEETLKTT 167
>UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
NAD-dependent; n=9; Clostridiales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase NAD-dependent -
Clostridium perfringens
Length = 282
Score = 70.9 bits (166), Expect = 2e-11
Identities = 46/167 (27%), Positives = 73/167 (43%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
EK+ ++G+G +G FA GY+V + D+ ++ + IA I L L G +
Sbjct: 2 EKIFVIGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVDRGIAGINKGLTKLVSKGKITEE- 60
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ + + GT DL +A D V E EN+E+KK++F LD + + TI
Sbjct: 61 DKEAVLSKITGTTDLGLAA-DCDLVIEAAVENMEIKKQIFAELDKICKEETILASNTSSL 119
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+VI H NP + LVE++ T E K +
Sbjct: 120 SITEVASATNRPDRVIGMHFFNPATIMKLVEVIRGMATSQETFDKVK 166
>UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 303
Score = 69.7 bits (163), Expect = 4e-11
Identities = 49/162 (30%), Positives = 77/162 (47%), Gaps = 2/162 (1%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
+VG+G IG WA LF++ G +V + D D +A + L + + R + D+
Sbjct: 1 MVGAGTIGLGWAALFSAHGLEVRITDP-----RDDLASVVGDAMPLLAESMGR---DPDQ 52
Query: 236 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 415
++ LA AV DA VQE PE LE K+ +F ++ +
Sbjct: 53 LLAGIEIADSLADAVSDADLVQENGPERLEFKQDLFADIARHAPPRAVLASSSSGIVASA 112
Query: 416 XXENMKHKA--QVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
E++ +++++HP NPP VPLVEIVP T+ VT+
Sbjct: 113 IAEHLPDDVAGRLLIAHPFNPPQVVPLVEIVPGERTEERVTE 154
>UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Flavobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Dokdonia donghaensis MED134
Length = 394
Score = 69.7 bits (163), Expect = 4e-11
Identities = 48/165 (29%), Positives = 81/165 (49%), Gaps = 3/165 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ +GI+G+G +G A + A+ G V LFDV ++ + A ++ LK L + +G +
Sbjct: 3 KNIGIIGAGTMGSGIAQVAATAGCAVKLFDVNQEALDKAKEALEKVLKRL----IEKGRI 58
Query: 224 NADEQFQCVKGTCDLAIAVKD---AIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
+A E+ + ++ +K+ A E + ENLE+KKKVFQ L+ V D I
Sbjct: 59 DASEKDR-IQANITYVTTLKELANADLTIEAIVENLEVKKKVFQELETYVSDTAIIASNT 117
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
++++ + I H NP + LVE++PA T V
Sbjct: 118 SSLSIASIAASLQNPERCIGIHFFNPAPLMKLVEVIPAVQTSQNV 162
>UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 317
Score = 69.3 bits (162), Expect = 5e-11
Identities = 45/164 (27%), Positives = 79/164 (48%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+G+VG+GL+G A A G++ + DV ++ + L L G +
Sbjct: 19 IGVVGTGLMGVGIATQSALHGHRTIVHDVDPARLASVAPKAQAVLDELIDAGRIDPAAK- 77
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
++ +L + + A FV E +PE LELK +++ L ++ D+ I
Sbjct: 78 QAALARIETHAELDV-MASAQFVIEAIPEVLELKHRLYAALTQLLADDAILASNTSGFHP 136
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
++ K + +++H NPP+ +PLVE+VP T PEVT++T
Sbjct: 137 DQLAAPLRAKDRFVIAHFWNPPHMIPLVEVVPGTATAPEVTQQT 180
>UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 308
Score = 69.3 bits (162), Expect = 5e-11
Identities = 42/166 (25%), Positives = 81/166 (48%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KV ++G+G IG S+A + + + I D +D+ ++ G
Sbjct: 7 KVTLIGTGTIGLSFA------AFHLAKLSPSQLTIYDTRSDLSTYIEEFLPKFFESGKSP 60
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
AD ++ L AV D+ +QE PENL++K+K+++ ++ ++ +
Sbjct: 61 AD--LSEIRLAVTLQEAVSDSHIIQESGPENLDVKRKLWKEVEKYAPNDALLWSSTSGIP 118
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
++M+ K +++V HP NPP+ +PL+E+VP+ T V +T+
Sbjct: 119 ASQQAQDMQDKTRLLVVHPYNPPHIMPLLELVPSSETSDTVISRTQ 164
>UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein; n=19; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein - Croceibacter
atlanticus HTCC2559
Length = 802
Score = 68.5 bits (160), Expect = 9e-11
Identities = 52/183 (28%), Positives = 86/183 (46%), Gaps = 16/183 (8%)
Frame = +2
Query: 29 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDA------IADIKVQLKT 190
+K + K+ ++GSG++G A FA++G +V L D+V +++ + + KV
Sbjct: 2 AKRRINKIAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELNEKEKAKGLTLEDKVVRNR 61
Query: 191 LEKDGL---LRGN----LNADEQFQCVKGTCDLAIA-VKDAIFVQECVPENLELKKKVFQ 346
+ D L ++ + D + G + IA VKD ++ E V E L++KK+VF+
Sbjct: 62 IVNDALQSSIKSKPAPLYHKDFASRISTGNLEDDIAKVKDVDWIIEVVVERLDIKKQVFE 121
Query: 347 NLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQ--VIVSHPVNPPYYVPLVEIVPAPWTK 520
NL+ + T+ E Q +H NPP Y+ L EI+P P T
Sbjct: 122 NLEKHRTEGTLITSNTSGIPINLMSEGRSEDFQKHFCGTHFFNPPRYLELFEIIPGPKTS 181
Query: 521 PEV 529
PEV
Sbjct: 182 PEV 184
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 68.1 bits (159), Expect = 1e-10
Identities = 42/165 (25%), Positives = 74/165 (44%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+ I+G G +G A A G QV +DV I A + + V L+ G+ +
Sbjct: 5 IAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPSAGV 64
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
V+ T D+ AV A V E VPEN+ +K V++ +D ++ +TI
Sbjct: 65 GT----VRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPI 120
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
++ + +++ H NPP+ +P++E++ T P+ R
Sbjct: 121 TKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIR 165
>UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Myxococcus xanthus DK 1622|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Myxococcus xanthus
(strain DK 1622)
Length = 321
Score = 68.1 bits (159), Expect = 1e-10
Identities = 44/167 (26%), Positives = 77/167 (46%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+++G+VG G +G A+ A G QV L++ A A ++ L + GLL
Sbjct: 7 KRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERARAKLERDASLLVETGLLAPE- 65
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A ++ T LA A + V E +PE+L LK+++F+ LD + +T+
Sbjct: 66 QAPAAIGRIRRTTVLAEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLATNTTAL 125
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ +V+ +H P + +PLV+I+P T P+ + R
Sbjct: 126 SVTAIARDCTRPERVLSAHYYLPAHLIPLVDIIPGEKTSPDAVETVR 172
>UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Ignicoccus hospitalis KIN4/I|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Ignicoccus hospitalis KIN4/I
Length = 683
Score = 67.7 bits (158), Expect = 2e-10
Identities = 52/170 (30%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KV +VG+G++G A + A G V + D+ ++ + A+ IK L+ L G L+
Sbjct: 25 KVLVVGAGVMGHGIAQVAAMSGLNVRMIDIKQEFLDRAMERIKESLEKLYAKGKLKEPPE 84
Query: 227 AD-EQFQCVKGTCD----LAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 391
++ + + D A A KD FV E VPE LELK+ VF LD + I
Sbjct: 85 EVLKRIETMVANPDDESSYAEAAKDVDFVIEAVPEKLELKRAVFSVLDKYAPPHAILASN 144
Query: 392 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
+ K +V+ H NPP + LVE+V T E K T
Sbjct: 145 TSSIPITEIAKATKRPDKVVGMHFFNPPVILKLVEVVRGKETSDETVKIT 194
>UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=2; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Jannaschia sp. (strain CCS1)
Length = 466
Score = 67.7 bits (158), Expect = 2e-10
Identities = 51/156 (32%), Positives = 73/156 (46%), Gaps = 4/156 (2%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLL-R 214
K I+G G+IG WA F G+ V ++D E++I + + + + L L L
Sbjct: 2 KTAIIGGGVIGGGWAARFLLNGWNVAIYDPDPEAERKIGEVMDNARRALPGLYDTALPPE 61
Query: 215 GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
G L + T DL AV DA +VQE VPE L++K KV L + +
Sbjct: 62 GTL---------RFTDDLGDAVGDADWVQESVPERLDIKHKVHAELTTLAPGRAVIGSST 112
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
E A+VIV+HP NP Y +PL+E+V
Sbjct: 113 SGFKPSELTEK---GARVIVAHPFNPVYLLPLIELV 145
>UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=31;
Proteobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 518
Score = 66.9 bits (156), Expect = 3e-10
Identities = 46/162 (28%), Positives = 75/162 (46%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
VG++G+G +G A + A+ G+ V L+D+ E A+A I+ Q L + G L A
Sbjct: 20 VGVIGAGAMGAGIAQVAAAAGHTVLLYDLNEAACDKALAGIRAQFARLAEKGRLE-PAQA 78
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
D ++ +LA A+ V E E L++K+++F L+ VDD +
Sbjct: 79 DAAGARIRAVRELADFAGAALIV-EAAAERLDVKREIFATLERHVDDACLLATNTSSISI 137
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
++ +V H NP + LVE+V T PEV +
Sbjct: 138 TSIAAGLRVPQRVAGLHFFNPAPLMALVEVVSGLATAPEVAQ 179
>UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD binding
domain; n=2; Gammaproteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, C-terminal:3-hydroxyacyl-CoA
dehydrogenase, NAD binding domain - Azotobacter
vinelandii AvOP
Length = 307
Score = 66.9 bits (156), Expect = 3e-10
Identities = 47/163 (28%), Positives = 75/163 (46%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
I+G+GL+G A A G+ V L D +++ + L L G D
Sbjct: 8 ILGAGLMGIGIATHLARHGHAVLLRDPAAERLAEVPVMAGSILAELADAGRFE-RAQTDA 66
Query: 236 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 415
+ + LA V DA + E +PE LELK+ ++ L+ +V T+
Sbjct: 67 TLARLAVSPRLA-DVADARLLIEAIPERLELKRALYAELEALVGTGTVIASNTSGLPPDA 125
Query: 416 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
E M+H +++++H NPP+ +PLVEIVP T+ E + R
Sbjct: 126 LAEGMRHPERLLIAHFWNPPHLIPLVEIVPGSATRAEHLEAVR 168
>UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=3; Geobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Geobacter sp. FRC-32
Length = 289
Score = 66.9 bits (156), Expect = 3e-10
Identities = 48/158 (30%), Positives = 76/158 (48%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
VG+ G+G +G A + A G QV + D+ E+ A I L+ + K G +
Sbjct: 9 VGMAGAGSMGAGIAQIAAMAGLQVKVVDMSEEVWGRAKKTIVKSLERVVKKGTITEK-EM 67
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
+E + + D+A ++KD F+ E V E++ +KK++F LD V D+TI
Sbjct: 68 EETLGRISFSTDVA-SLKDVPFIFEAVFEDINVKKELFAKLDAVCGDDTIYATNTSSISI 126
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKP 523
+K+ A I H NP + LVE++PA T P
Sbjct: 127 TEMAALVKNPANFIGMHFFNPVPVMKLVEVIPALQTAP 164
>UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like
protein; n=1; marine actinobacterium PHSC20C1|Rep:
3-hydroxyacyl-CoA dehydrogenase-like protein - marine
actinobacterium PHSC20C1
Length = 288
Score = 66.1 bits (154), Expect = 5e-10
Identities = 47/164 (28%), Positives = 72/164 (43%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
K+ +VGSG +G L A G V +FDV E + A A + L+ + + +
Sbjct: 5 KLAVVGSGTMGHGIGQLAAMQGIAVRVFDVDEVALDRARASVATSLERFVRKETITDAQS 64
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
+ Q + + T DL A+ E VPE L LK+KVF +LD +
Sbjct: 65 HEIQGR-MDWTTDLDAALVGVEAAIEAVPEVLALKQKVFTDLDERTGPEVMLATNTSQLS 123
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
+ KH +V+ H NPP + LVEI+ T E+ ++
Sbjct: 124 ITTIASSAKHPERVVGMHFFNPPVVMRLVEIIRGTMTSDEMLQR 167
>UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Psychrobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Psychrobacter cryohalolentis
(strain K5)
Length = 533
Score = 65.7 bits (153), Expect = 7e-10
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 4/168 (2%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ + I+G+G++G A + A VG QV LFD ++ L+ L G
Sbjct: 4 KSLAIIGTGIMGMGIAQIAAQVGIQVLLFDAKAGAAEQGRQSLQAMLEKLAAKGKF---- 59
Query: 224 NADEQFQCVKGTC----DLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 391
DEQ Q D+A + +A V E + ENLE+K+++F+ L+++V TI
Sbjct: 60 -TDEQLQSTLKNLIVIEDIA-KIAEADVVIEAIIENLEIKQQLFKQLESIVPAETILATN 117
Query: 392 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
N +H +V H NP + +VE++P TK V +
Sbjct: 118 TSSLAVTAIASNCEHPERVAGFHFFNPVPLMKIVEVIPGISTKSSVVE 165
>UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelotomaculum thermopropionicum SI|Rep:
3-hydroxyacyl-CoA dehydrogenase - Pelotomaculum
thermopropionicum SI
Length = 319
Score = 65.7 bits (153), Expect = 7e-10
Identities = 45/164 (27%), Positives = 70/164 (42%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+ I+G+G +G S A G V L DV + A I+ L + G +G
Sbjct: 7 LAIIGAGTMGHSIAAAALQHGVSVRLIDVSAPALETARRKIQSYLASAAGKGGGKGGAVP 66
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
++ ++A V A V E VPE L+LKK++F LD + + I
Sbjct: 67 GHLAGVLETCMEMAAGVTGADMVIEAVPEKLDLKKEIFAQLDKLCPPSVILATNTSGLPI 126
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
+V+ +H P Y +PLVE+V + +T P+V T
Sbjct: 127 TAIASAAARPERVLGTHFYMPAYLIPLVEVVCSDYTSPDVAGDT 170
>UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precursor;
n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
precursor - Pseudomonas putida W619
Length = 313
Score = 65.7 bits (153), Expect = 7e-10
Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
++G+GL+G A +FA G++V+L+D T +A +V L++ G+ + A+
Sbjct: 9 VIGAGLMGHGIAQVFAQAGHKVSLYD--PDAATLDLAPQRVA-HNLDQMGIASAPILAN- 64
Query: 236 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 415
+ DL AV +A V E VPE LELK+K+F ++ +T+
Sbjct: 65 ----IALFTDLREAVSNADIVIEAVPERLELKQKLFADIAGFAPPHTVLASNTSVIPITE 120
Query: 416 XXENM--KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
E + + +A+++ +H NPP+ VPLVE+V T V + T
Sbjct: 121 IGEMLGSEARARLVGTHWWNPPHLVPLVEVVRTEHTSLSVFEST 164
>UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Archaeoglobus fulgidus
Length = 295
Score = 65.3 bits (152), Expect = 9e-10
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 2/161 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+G+VG+G++G A + A GY V + DV E+ + A+ I+ L + + +G ++
Sbjct: 9 IGVVGAGVMGHGIAQVAARTGYDVVMVDVSEEVLKKAMELIESGPFGLRRL-VEKGKMSE 67
Query: 230 DEQFQCVKG--TCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
DE + T A+KDA F+ E V E +LKKK+F LD + TI
Sbjct: 68 DEAKAVMARIRTSTSLEALKDADFIIEAVTEKADLKKKIFAELDRICKPETIIASNTSAI 127
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
++ K + I H NP + L+E++ T E
Sbjct: 128 MISDLATAVERKDKFIGMHWFNPAPVMRLIEVIRGALTSDE 168
>UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-coA dehydrogenase -
Clostridium tetani
Length = 282
Score = 64.9 bits (151), Expect = 1e-09
Identities = 45/161 (27%), Positives = 72/161 (44%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+K+ ++G+G +G A FA+ GY+V L D+ ++ + I I+ L L G +
Sbjct: 2 KKICVLGAGTMGAGIAQAFAAKGYEVVLRDIKDEFVERGIKGIEKGLSKLVSKGRM-AQE 60
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ D ++GT DL A D V E EN+E+K+++F LD + TI
Sbjct: 61 DMDSILGRIEGTVDLNKAA-DCDLVVEAAIENMEIKREIFAELDRICKPETILSSNTSSL 119
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+VI H NP + L+EI+ T E
Sbjct: 120 SITEIATATNRPDKVIGMHFFNPAPVMKLIEIIRGMATSQE 160
>UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)]; n=20;
Rickettsia|Rep: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)] - Rickettsia typhi
Length = 720
Score = 64.9 bits (151), Expect = 1e-09
Identities = 42/167 (25%), Positives = 81/167 (48%), Gaps = 2/167 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+KV ++G+G++G A L A+ ++V L D+++K D +K +K L + L +
Sbjct: 6 KKVCVIGAGVMGSGIAALIANSSHRVVLLDILDKDSNDPNKIVKNAVKNLHRQKLPPLSY 65
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
F + +K+ V E + E L++K +++ + + ++TI
Sbjct: 66 PDKVNFITIGNLEHDLDLIKECNLVIEVIVEKLDIKHQLYNKIIPYLKEDTIIASNTSTL 125
Query: 404 XXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
EN+ + K++ I++H NPP Y+ LVE++ K EV +K
Sbjct: 126 PLKKLKENLPNNIKSRFIITHFFNPPRYMELVELIIDNTIKDEVIEK 172
>UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=8; Mycobacterium tuberculosis complex|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Mycobacterium tuberculosis
Length = 304
Score = 64.5 bits (150), Expect = 2e-09
Identities = 49/164 (29%), Positives = 79/164 (48%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+ +VG+GL+GR A + AS G V + D +I A A ++ G RG++
Sbjct: 9 RAAVVGAGLMGRRIAGVLASAGLDVAITDT-NAEILHAAA-----VEAARVAGAGRGSVA 62
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
A DLA A+ DA V E V ENL +K+++F+ L + D +
Sbjct: 63 A---------AADLAAAIPDADLVIEAVVENLAVKQELFERLATLAPD-AVLATNTSVLP 112
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
E ++ ++VI +H NPP +P+VE+VP+ T P+ +
Sbjct: 113 IGAVTERVEDGSRVIGTHFWNPPDLIPVVEVVPSARTAPDTADR 156
>UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 485
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 3/167 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+G++G+G +G A + A+ G++V LFDV + +L TL K G + A
Sbjct: 11 IGVIGAGTMGAGIAQVAAAAGHKVLLFDVASGAAASGLERTAKELATLVKRGKME-QKRA 69
Query: 230 DEQFQCVKGTCDLAIAVKD---AIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
+E + G +A ++D A E + E L++K+KVF L+ ++ ++ I
Sbjct: 70 EE----IIGRITIAEKLEDLAPAALTVEAIVERLDVKQKVFAQLEAILAEDAILATNTSS 125
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
+K +++ H NP + LVE+V T PEV + T
Sbjct: 126 ISITAIGAALKRPERLVGMHFFNPAPIMKLVEVVSGLATSPEVAQIT 172
>UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
unidentified eubacterium SCB49|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - unidentified eubacterium SCB49
Length = 403
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/164 (28%), Positives = 76/164 (46%), Gaps = 2/164 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDGLLRGN-L 223
+GI+G+G +G A + A+ G V LFD+ + + A A + K+ + +EK +
Sbjct: 20 IGIIGAGTMGSGIAQVAATAGCTVKLFDLNQAALDKAKASLEKIMTRLVEKGRVTEEEKA 79
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
E V +LA D+ E + E+L +KKKVFQ L++ V D+ I
Sbjct: 80 RIQENISYVNALKELA----DSDLTIEAIIEDLGIKKKVFQELESYVSDSCIIASNTSSL 135
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
+++ + + H NP + LVE++PA T V K
Sbjct: 136 SIASIASSLQKPERCVGIHFFNPAPLMKLVEVIPAIQTSDAVLK 179
>UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Halobacteriaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 654
Score = 64.5 bits (150), Expect = 2e-09
Identities = 44/163 (26%), Positives = 73/163 (44%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V ++G+G +G A + A GY V L D+ + D +I+ L+ L + G L + +
Sbjct: 11 VAVLGAGTMGHGIAEVAAIAGYDVVLRDIDAAIVEDGYDEIEWSLEKLAEKGRL--DEDP 68
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
D+ V T DL AV DA V E PE L +K+ +F+++D + +
Sbjct: 69 DDVAARVATTTDLEAAVSDADLVIEAGPEQLSVKQDIFESVDAAAPADALLATNSSSLSI 128
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
+ V+ H NPP + LVE++ T E ++
Sbjct: 129 TEIAAATERPESVLGLHFFNPPVKMDLVEVIYGKATTDETAQR 171
>UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=48; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Burkholderia mallei
(Pseudomonas mallei)
Length = 331
Score = 64.1 bits (149), Expect = 2e-09
Identities = 47/171 (27%), Positives = 67/171 (39%)
Frame = +2
Query: 14 RVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTL 193
R MA K + +G+G+IG W + G V +D E A+++ L
Sbjct: 8 RKYMAVITKIDTFAAIGAGVIGSGWVARALANGLDVLAWDPAEDAEMQLRANVENAWPAL 67
Query: 194 EKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDN 373
E+ GL G A F C V DA FVQE PE LK ++ + + +
Sbjct: 68 ERAGLAPGASPARLHFVPTIEAC-----VADADFVQESAPEREALKLELHERISRAAKPD 122
Query: 374 TIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
I + IV HP NP Y +PLVE++ T P+
Sbjct: 123 AIIASSTSGLLPTDFYARAHRPERCIVGHPFNPVYLLPLVEVLGGERTAPD 173
>UniRef50_O69856 Cluster: Fatty acid oxidation complex
alpha-subunit; n=6; Actinobacteria (class)|Rep: Fatty
acid oxidation complex alpha-subunit - Streptomyces
coelicolor
Length = 709
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 1/153 (0%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
KVG+VG+GL+ A+LF + V L D+ ++++ + + ++ L G + +
Sbjct: 340 KVGVVGAGLMASQLALLFLRRLEVPVVLTDIDQERVDKGVGYVHAEIDKLLGKGRVNQD- 398
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A+ V G D A DA FV E V E + +K+KVF ++ V + I
Sbjct: 399 KANRLKALVTGVLDKAEGFADADFVIEAVFEEMGVKQKVFAEVEAVAPAHAILATNTSSL 458
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+KH +V+ H NP +PL+EIV
Sbjct: 459 SVSEMASKLKHPERVVGFHFFNPVAILPLLEIV 491
>UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD
binding domain; n=2; Azotobacter vinelandii|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain -
Azotobacter vinelandii AvOP
Length = 208
Score = 63.7 bits (148), Expect = 3e-09
Identities = 43/162 (26%), Positives = 75/162 (46%), Gaps = 3/162 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+ I+GSG +G A A G++V L +Q+ + +A + L GL+ A
Sbjct: 6 IAILGSGSMGVGIATHLARHGHEVLLIYPSMEQLAEVLAMARSILA-----GLVEAGRFA 60
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQ---ECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
EQ + +KD V+ E +PE +ELK+ ++ L+ +VD +
Sbjct: 61 PEQVAATLARLRTSTRLKDVAGVRLLIETLPERIELKRALYAELERIVDAEAVIASDTGG 120
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
E M+H +++++H +PP+ VPLV +V T+ E
Sbjct: 121 LSPERLAEGMRHPGRLLIAHFRSPPHRVPLVAVVAGRQTRSE 162
>UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Caulobacter sp. K31
Length = 348
Score = 63.3 bits (147), Expect = 4e-09
Identities = 47/154 (30%), Positives = 71/154 (46%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ V ++G+GL+G A +FA+ GY V LFD T A I + ++ G
Sbjct: 47 QPVAVLGAGLMGAGIAKVFAAKGYPVFLFDRDLDTATSATRQINGAIAHVD------GGR 100
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ D LA AV DA FV E V E L++K+++F L + +
Sbjct: 101 DVD-------AAGSLAEAVADAAFVFESVSEKLDVKRRIFSALAECARHDAVLASNTSAI 153
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVP 505
E + +A+++ SH NP VPLVE+VP
Sbjct: 154 PITQIAEGLPCEARIVGSHWWNPADVVPLVEVVP 187
>UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Pseudomonas fluorescens PfO-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Pseudomonas fluorescens (strain PfO-1)
Length = 703
Score = 62.5 bits (145), Expect = 6e-09
Identities = 46/164 (28%), Positives = 73/164 (44%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 217
K KV ++G+G +G AM FA VG V L D+ + + + ++ + K G L
Sbjct: 297 KINKVAVIGAGTLGGGIAMSFADVGIPVALMDLDGRTLDRGLKRVRENYQLSVKRGKLSA 356
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
+ ++ + + GT D A + DA + E V E +E K +VF L++V I
Sbjct: 357 -VQMQQRMELLFGTLDYA-DLSDADLIIEAVCEKMESKHQVFLALESVCKPGAILATNTS 414
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ + VI H +P + LVEIV T P+V
Sbjct: 415 SLDIDALAKMVSRPQDVIGMHFFSPANVMRLVEIVLCQTTAPDV 458
>UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase; n=19;
cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase -
Aeropyrum pernix
Length = 669
Score = 62.5 bits (145), Expect = 6e-09
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 7/180 (3%)
Frame = +2
Query: 23 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 202
MA + K+ + +VG+G +G A L A G++V L D+ + +A+ I+ L+ L +
Sbjct: 1 MAGEVKT--ITVVGAGTMGHGIAELAAIAGFKVYLADINIDILNNALQRIRWSLEKLAEK 58
Query: 203 GLLRGN----LNADEQFQCVKG---TCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNV 361
G +R + ++ V+ + DLA A+ ++ F+ E +PE LELK+++F D
Sbjct: 59 GRIRESVETVMSRITPIVSVRDGEYSEDLAKALSESDFMIEAIPEKLELKQQLFAFADKH 118
Query: 362 VDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
+ I +V+ H NPP +PLVE+V T E T
Sbjct: 119 AKETAILASNTSSLPITEIAAATSRPEKVVGMHFFNPPVLMPLVEVVKGEKTSEETVAAT 178
>UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Halobacteriaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 669
Score = 62.5 bits (145), Expect = 6e-09
Identities = 42/154 (27%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTL-EKDGLLRGN 220
+ + ++G+G +G + A GY V + D+ ++ + D +I+ L L E+D L +
Sbjct: 22 DTIAVLGAGNMGHGITEVAALAGYDVRMRDIKDEFVEDGYDNIEWSLNKLAERDQLTQEE 81
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
AD V D+ AV D V E VPE +E+KK V+ ++ +N I
Sbjct: 82 --ADAALDRVTPLVDVEEAVSDVDVVIEAVPEKMEIKKDVYTEVEEHAPENAIFATNTSS 139
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
E + Q H NPP + LVE++
Sbjct: 140 LSITELSEVTERPEQFCGMHFFNPPVRMQLVEVI 173
>UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Firmicutes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus sp. NRRL B-14911
Length = 295
Score = 62.1 bits (144), Expect = 8e-09
Identities = 43/164 (26%), Positives = 71/164 (43%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ + +VG+G +G AML A G++ TL D+ EK + A ++ + G L
Sbjct: 8 KNITVVGAGQMGHQIAMLCALGGFETTLHDMQEKALDQAQEKLRGIMDKWAAKGKLPSE- 66
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ F ++ T D AVK A F+ E V E LE+K++VF L+ + + I
Sbjct: 67 QIEAAFSRLRCTSDFGEAVKSADFIIEAVVEKLEVKREVFSMLEEMAPPHAIFATNSSTI 126
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
+ + H PP + VE+V + T E +
Sbjct: 127 VNSLLANAADRPEKTVNMHFFFPPLVMDCVEVVMSSRTSEETAE 170
>UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 295
Score = 62.1 bits (144), Expect = 8e-09
Identities = 46/168 (27%), Positives = 75/168 (44%), Gaps = 3/168 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN- 226
V I+G+G +G A + A G+ V+L D+ + D + I+ L+ +G+ R +
Sbjct: 4 VAILGAGTMGHGIAQVSAMAGHDVSLRDIEADIVDDGLTAIESNLE----EGIAREKVTE 59
Query: 227 --ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
A+ +KGT L AV A V E VPE + +K + +++ VD T+
Sbjct: 60 STAEATIDRLKGTTSLEEAVTGADLVVEAVPEEMAIKHETLTAVESHVDPATLIASNTSS 119
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ + + I H NP + + LVEIV A T E + R
Sbjct: 120 LSLTEIASVLDYPERAIGLHFFNPVHIMALVEIVVAEQTSAETIARAR 167
>UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase; n=4; Crenarchaeota|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase - Cenarchaeum
symbiosum
Length = 365
Score = 62.1 bits (144), Expect = 8e-09
Identities = 40/156 (25%), Positives = 67/156 (42%)
Frame = +2
Query: 74 IGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADEQFQCVK 253
+G A + A+ GY+V L D+ ++ + A+ I+ L + G + D ++
Sbjct: 1 MGHGIAQVSAASGYEVVLRDIEQRFLDSAMEKIRWSLDKMASKGRITAE-EKDGILNRIR 59
Query: 254 GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMK 433
L A++ A V E VPE ++LK+KV+ LD + +
Sbjct: 60 PVVALGEALEGADLVIEAVPEVMDLKRKVYAELDAAAPEGAAFASNTSTLPITEIAQATS 119
Query: 434 HKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
+ I H NPP + LVE++P T E T+ T
Sbjct: 120 RPERFIGIHFFNPPQLMKLVEVIPGEGTSDETTRMT 155
>UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Rep:
Blr6087 protein - Bradyrhizobium japonicum
Length = 330
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/173 (27%), Positives = 78/173 (45%), Gaps = 8/173 (4%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDV-------VEKQITDAIADIKVQLKTLEKDGL 208
+ +G+G +GR A+ FA G++VT+ DV K TDA+ +++ +L GL
Sbjct: 7 IACLGAGRMGRGIAVAFAYAGHRVTMIDVKPRSAEDFAKLETDALGEVRKTFASLSNLGL 66
Query: 209 L-RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 385
L +++ V A+ DA V E VPE +ELK++V V +TI
Sbjct: 67 LTEADVDPLVARVSVATASQSGTALADAGMVFEGVPEVVELKREVLGAASRQVKPDTIIA 126
Query: 386 XXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ + + + H +NP Y +PLVE+ P T P + + +
Sbjct: 127 STTSTILVDDLSGAIVNPHRFLNVHWLNPAYLIPLVEVSPGKATDPAIIDEVK 179
>UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr11 scaffold_13, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 724
Score = 61.7 bits (143), Expect = 1e-08
Identities = 41/162 (25%), Positives = 73/162 (45%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+KV ++G GL+G A + V L +V + + I I+ ++ L G L +
Sbjct: 309 KKVAVIGGGLMGSGIATALITSNIYVVLKEVNSEYLLKGIKTIEANVRGLVTKGKLTQD- 367
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A + +KG D + KD V E V EN+ LK+K+F ++ + + I
Sbjct: 368 KARKALSMLKGVLDYS-EFKDIDMVIEAVIENISLKQKIFSEIEKICSPHCILATNTSTI 426
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
E + ++I +H +P + +PL+E+V T +V
Sbjct: 427 DLNLVGEKTSSQDRIIGAHFFSPAHVMPLLEVVRTEKTSAQV 468
>UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Halobacterium salinarium (Halobacterium halobium)
Length = 286
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/170 (25%), Positives = 80/170 (47%), Gaps = 1/170 (0%)
Frame = +2
Query: 23 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEK 199
M S +E +G+VG+G +G A + A+ GY V + D+ ++ + I+ L + +
Sbjct: 1 MRSLADTETIGVVGAGTMGAGIAQVAATAGYTVVMRDIEQEYVDAGFDSIESSLDRFVSN 60
Query: 200 DGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 379
D L +AD + GT DLA + D V E E++E+K+ +F++LD+ + ++ +
Sbjct: 61 DDL--SEADADAIVDRITGTTDLA-ELADCDVVIEAAVEDMEIKQDIFRDLDDALPEDVV 117
Query: 380 XXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
++V+ H +NP + VE+V T +V
Sbjct: 118 LATNTSTLSITTIASVTDRASRVVGLHFMNPVPIMTGVEVVVGEKTDADV 167
>UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 286
Score = 61.3 bits (142), Expect = 1e-08
Identities = 44/159 (27%), Positives = 72/159 (45%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
VG+VG+G +G A A G+ V + D + + A + ++ L+ G G A
Sbjct: 9 VGVVGAGTMGAGVAECLAQAGHDVIVVDPDPQAVDQARSRMRDSLRLAILLGRAGGPKPA 68
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
+ + V T ++ ++DA V ECVPE ++LK+KVF LD V + +
Sbjct: 69 EVTAR-VHWTGEMT-DLRDAAVVIECVPERIDLKEKVFAELDRVCAPDALLASCTSGIPV 126
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+ +V+ H +NP VE+V P T P+
Sbjct: 127 DRLADTTTRPERVVGLHFMNPAPLKDTVEVVRGPRTSPQ 165
>UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Acinetobacter
baumannii (strain ATCC 17978 / NCDC KC 755)
Length = 233
Score = 61.3 bits (142), Expect = 1e-08
Identities = 26/82 (31%), Positives = 44/82 (53%)
Frame = +2
Query: 293 FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNP 472
F+QE PE L+LK+ ++Q + + + T+ ++ H ++ + HP NP
Sbjct: 6 FIQENAPERLDLKQNLYQEITSYCPEKTLIASSSSGLKVSDFQKDATHPERIFLGHPFNP 65
Query: 473 PYYVPLVEIVPAPWTKPEVTKK 538
P+ +PLVEIV T P++ KK
Sbjct: 66 PHLLPLVEIVGGKLTDPQILKK 87
>UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 287
Score = 61.3 bits (142), Expect = 1e-08
Identities = 47/160 (29%), Positives = 71/160 (44%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
+VG+G +G A L A G++V + D+ + A A I+ L+ + G L D
Sbjct: 8 VVGAGNMGAGIAQLCAQQGFEVVIADISLELSDKAKARIEKGLRKRVEQGKLDA-AQKDA 66
Query: 236 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 415
++ DL A FV E V E++ +K+KVF LDN+ TI
Sbjct: 67 ILSRIQTAGDLGPAAV-CRFVIESVIEDIAIKRKVFAELDNLSPPETILATNTTSLSISA 125
Query: 416 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
E + +V+ H NPP + LVEI+P T E +
Sbjct: 126 MAEATRRPERVVQMHFFNPPVIMKLVEIMPGKKTSRETVE 165
>UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=12; Actinomycetales|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 723
Score = 61.3 bits (142), Expect = 1e-08
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 2/163 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFA-SVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 220
KVG+VG+GL+ A+LFA + V + D+ + ++ + + ++ K L K +
Sbjct: 350 KVGVVGAGLMASQLALLFARQLKVPVVMTDIDQARVDKGVGYVHAEVDKMLAKKRISADA 409
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
N + V G+ A DA FV E V E L +KK+VF ++ +V I
Sbjct: 410 ANRTKAL--VTGSVSKD-AFADADFVIEAVFEELNVKKQVFAEVEAIVSPECILATNTSS 466
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
++ H +++ H NP +PL+EIV AP T V
Sbjct: 467 LSVTAMAADLAHPERLVGFHFFNPVAVMPLLEIVRAPKTDDAV 509
>UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4;
Trichocomaceae|Rep: RIB40 genomic DNA, SC009 -
Aspergillus oryzae
Length = 337
Score = 61.3 bits (142), Expect = 1e-08
Identities = 47/172 (27%), Positives = 72/172 (41%), Gaps = 13/172 (7%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL-- 223
V I+G+G+IG SW LF + G +V + D + + Q TL + GL G
Sbjct: 12 VAIIGTGVIGASWTALFLARGLKVLVTDPAPNAEKNLETYLNAQWPTLTQIGLSEGASLK 71
Query: 224 ------NADEQFQCVKGTCDLAIAVKDA----IFVQECVPENLELKKKVFQNLDNVVDDN 373
+ D F+ + ++ + + V + PE LE K+ +F LD
Sbjct: 72 NYAFVDSLDNHFEEIDFIQEVPFPFSNTGVILLTVTKNGPERLEFKRTLFAYLDEKARPE 131
Query: 374 TIXXXXXXXXXXXXXXENMKHKAQ-VIVSHPVNPPYYVPLVEIVPAPWTKPE 526
I +H + V+V HP NPP+ +PLVE+VP T E
Sbjct: 132 VIIASSSSGIPSSEYASACRHHPERVLVGHPFNPPHLIPLVEVVPHRTTDRE 183
>UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Roseovarius sp. HTCC2601
Length = 220
Score = 60.5 bits (140), Expect = 2e-08
Identities = 42/168 (25%), Positives = 75/168 (44%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 220
S ++ +VG+G +G A L+A GY + D + D V+ GL+ +
Sbjct: 13 SGRICVVGAGFMGCVIATLYAHHGYDAVICD-----SNQTMLDTYVERARPIAAGLVEDS 67
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
++ V DLA A++ V E V E+LE+K+ +F L+ + +N +
Sbjct: 68 DASEAMLAGVTLEPDLASAIEGVFLVHEAVQESLEVKQALFAELERICPENVVLATNTSS 127
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
M K +++ H V P + VP++E++ A T E+ +R
Sbjct: 128 FLISDIAAQMTRKERMMGIHYVTPGHIVPVIELIHAADTPAELVAWSR 175
>UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=8; Enterobacteriaceae|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Escherichia coli
(strain K12)
Length = 475
Score = 60.5 bits (140), Expect = 2e-08
Identities = 46/165 (27%), Positives = 72/165 (43%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ V ++GSG +G A + AS G+QV L+D+ + +T AI I +L + G L
Sbjct: 6 QTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAET 65
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ + T A+A D + E E LE+KK +F L V T+
Sbjct: 66 CERTLKRLIPVTDIHALAAADLVI--EAASERLEVKKALFAQLAEVCPPQTLLTTNTSSI 123
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
+K+ +V H NP + LVE+V T EV ++
Sbjct: 124 SITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQ 168
>UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
root|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Thermobifida fusca (strain YX)
Length = 398
Score = 60.1 bits (139), Expect = 3e-08
Identities = 47/164 (28%), Positives = 73/164 (44%), Gaps = 3/164 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KVG+VG G +G +FA G+ VT ++ + + ++ K+L K + +G L
Sbjct: 7 KVGVVGLGTMGAGIVEVFARAGFTVTGVEIDDAALERGRTHLE---KSLAK-AVAKGKLT 62
Query: 227 ADEQFQCVKGTCDLAIA---VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
DEQ + + G + + DA E VPE L++K+ VF +LD ++ I
Sbjct: 63 EDEQ-RAILGRVTFTTSRDDLADAHLAVEAVPERLDIKRSVFADLDRILPPAAILATNTS 121
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+VI H NP + LVEIV T+P V
Sbjct: 122 SLSVTEIAALTSRPGKVIGLHFFNPAPVMRLVEIVTTVVTEPHV 165
>UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenase;
n=2; Streptomyces|Rep: Putative 3-Hydroxyacyl-CoA
dehydrogenase - Streptomyces coelicolor
Length = 504
Score = 59.7 bits (138), Expect = 4e-08
Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 1/162 (0%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRG 217
S V +VG+G +G+ A + G+ V L+D V+ + +A I +L + +EKD L
Sbjct: 7 SSPVAVVGTGTMGQGIAQVALVAGHPVRLYDAVDGRAREAADAIGARLDRLVEKDRLTGA 66
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
+A GT + D V E V E L++K+++F+ L++VV D+ +
Sbjct: 67 ERDAARARLVPAGTLG---ELADCALVVEAVVERLDVKQELFRALEDVVGDDCLLATNTS 123
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKP 523
++ + + H NP +PLVE+V T P
Sbjct: 124 SLSVTAVGGALRVPGRFVGLHFFNPAPLLPLVEVVSGFATDP 165
>UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding
- Halorubrum lacusprofundi ATCC 49239
Length = 676
Score = 59.7 bits (138), Expect = 4e-08
Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 1/162 (0%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 220
++V ++G+G +G A + A GY V L D+ E+ + I+ L K EKD + G
Sbjct: 20 QRVTVLGAGNMGHGIAEVAALAGYDVALRDIEEEFVQGGYDQIEWSLGKLAEKDRI--GE 77
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
AD V+ DL ++ DA V E VPE + +KK V+ + + +
Sbjct: 78 DEADAALDRVEAFVDLEDSLADADVVVEVVPEKMAIKKDVYDEVVEYAPEEAVFVTNTSS 137
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
E + H NPP + LVE++ T +
Sbjct: 138 LSITELSEVTDRPERFCGMHFFNPPVRMDLVEVISGKHTSED 179
>UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 282
Score = 59.3 bits (137), Expect = 6e-08
Identities = 47/163 (28%), Positives = 74/163 (45%), Gaps = 3/163 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK---TLEKDGLLRG 217
KVG++G+G +G A +FA GY+V L DV + + +A IK L+ K +G
Sbjct: 5 KVGVIGAGTMGNGIAHVFAKSGYKVVLCDVKREFLDRGLATIKKNLEREVAKNKISQEQG 64
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
+ AD + ++ DLA D V E E E+K ++F++LD++ + I
Sbjct: 65 QVAADHIYPTLERK-DLA----DCDIVVEAASERFEIKAELFRDLDSICRPDVILATNTS 119
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
K +VI H NP + LVE++ T E
Sbjct: 120 SISITKIAAVTKRPDKVIGMHFFNPVPVMKLVEVIRGLATSDE 162
>UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=16;
Bacteroidetes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 298
Score = 58.8 bits (136), Expect = 8e-08
Identities = 45/161 (27%), Positives = 65/161 (40%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
I+GSG +G A FA G+QV L D + A+ I L+ G++ + +
Sbjct: 10 IIGSGTMGSGIAHSFAQFGFQVFLCDSNAAALNKAMLQISTNLERQISKGIIPDS-EKET 68
Query: 236 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 415
+ D A K V E VPE LE+K +F+ LD TI
Sbjct: 69 IISRITPITDFKEAAKTVSLVVEAVPELLEIKADLFKELDMHCPPETILASNTSSISITT 128
Query: 416 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
+VI H +NP + LVEI+ T E T++
Sbjct: 129 LASYTSRPEKVIGMHFMNPVPVMQLVEIINGLLTSSETTRR 169
>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bordetella parapertussis
Length = 354
Score = 58.4 bits (135), Expect = 1e-07
Identities = 43/153 (28%), Positives = 66/153 (43%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ + +VG+G +G A LFAS G+ V L D + +T A I+ QL D +
Sbjct: 50 QNLAVVGAGAMGSGIAALFASKGFDVVLIDPMAGALTRAAQVIERQLGVYAPDAIAPA-- 107
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
Q ++ L A A V E VPE L LK+ +F LD + D I
Sbjct: 108 -----MQRIRMDAGLEAACS-AQLVIEAVPEKLALKRDIFARLDTLCDPQAIFATNTSGL 161
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ + + + + +H P +PLVE+V
Sbjct: 162 SINDIAQAVTRRDRFVGTHFFTPADVIPLVEVV 194
>UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 443
Score = 58.4 bits (135), Expect = 1e-07
Identities = 43/161 (26%), Positives = 73/161 (45%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+VG++G+G +G AM FA+VG VT+ D + + ++ + G L
Sbjct: 43 RVGVIGAGTMGGGIAMSFANVGIPVTVCDTDGAALERGLERVRRNYEFSVARGRLDAATM 102
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
A + ++ DL +KDA V E V E++ LK+ +F+ LD +V + I
Sbjct: 103 A-ARLALIRAAVDLQ-DLKDADLVIEAVFEDMALKQDIFRKLDAIVHPDAILATNTSGLD 160
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ V+ +H +P + L+E+V T PEV
Sbjct: 161 IDEIAVVTRRPQDVVGAHFFSPAHVQKLLEVVRGARTAPEV 201
>UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=5; Burkholderiales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 511
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/158 (25%), Positives = 69/158 (43%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
+VG+G++G A + A G+ V L+D E +A + L L G L +
Sbjct: 17 VVGAGVMGVGIAQVAAQAGHAVMLYDAREGAAAEAKTKLAKSLDALVAKGKLTAQ-GVSQ 75
Query: 236 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 415
++ LA A A V E + E L++K+ +FQ L+ +V + +
Sbjct: 76 TLSRIEAIASLAAAAP-ARLVIEAIVEKLDVKRGLFQQLEAIVAADCVLATNTSSISVTA 134
Query: 416 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
++H A+++ H NP + LVE+V T P V
Sbjct: 135 IANGLQHPARLVGMHFFNPVPQMRLVEVVSGLQTDPAV 172
>UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Psychromonas ingrahamii 37|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Psychromonas ingrahamii (strain 37)
Length = 511
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/168 (24%), Positives = 76/168 (45%)
Frame = +2
Query: 32 KFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLL 211
K + V ++G+G +G A + A GYQV LFD+ + + +A +I+ QL+ K G +
Sbjct: 3 KLLFKTVAVIGAGAMGAGIAQVAAQSGYQVYLFDLAKGKAEEAKENIEKQLERRVKKGRM 62
Query: 212 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 391
+ + + +L+ + A V E + ENLE+K+ +F+ L+ + + I
Sbjct: 63 E-QQTLESTLLRIHCSSELS-EIASANLVIEAIVENLEIKQGLFKELETICSADCILASN 120
Query: 392 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
+K + I H NP + LVE++ T + +
Sbjct: 121 TSSISITAIASALKSPERFIGLHFFNPAPVMKLVEVIQGVATADNIAE 168
>UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 589
Score = 58.4 bits (135), Expect = 1e-07
Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 3/168 (1%)
Frame = +2
Query: 35 FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT-LEKDGLL 211
++ V I+G+G++GR A ++AS GY V + D +Q D +A +K + E G
Sbjct: 11 YRERPVAILGAGVLGRRIACIWASAGYDVQVRDPSPEQRADCVAYVKQHVVAYAEHTGAA 70
Query: 212 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 391
G + E DL V +A V E VPE ++LK F+ LD + + I
Sbjct: 71 PGEVTTSE---------DLKNTVNNAWLVIEAVPEKIQLKIDTFEQLDKLAPTDCILASN 121
Query: 392 XXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ + K +++ H PP V +VE++ +T P +
Sbjct: 122 SSSYKSSEMLDKVSDSAKPRILNMHYYMPP-QVMVVELMTNGFTDPSI 168
>UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=11; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Deinococcus radiodurans
Length = 347
Score = 58.0 bits (134), Expect = 1e-07
Identities = 43/167 (25%), Positives = 67/167 (40%)
Frame = +2
Query: 29 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGL 208
S + V + GSG++G A A G+ V L+D+ + I A + ++D
Sbjct: 50 SSMSIKTVTVCGSGVLGSQIAFQTAFHGFDVHLYDINDAAIAKARETLGKLQARYQQDLK 109
Query: 209 LRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 388
+ D F + D+A AVK V E +PEN+++K+K + L V D NTI
Sbjct: 110 VDAQQTGDA-FARISFFTDIAEAVKGVDLVIEAIPENMDIKRKFYNQLGEVADPNTIFAT 168
Query: 389 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
E + + H N + EI+ P T V
Sbjct: 169 NSSTLLPSQFMEETGRPEKFLALHFANEIWKFNTAEIMRTPRTDDAV 215
>UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 288
Score = 58.0 bits (134), Expect = 1e-07
Identities = 41/163 (25%), Positives = 80/163 (49%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 220
+ ++ + G+G++GR A++ A G++V+L+D A AD+ + N
Sbjct: 3 ASQISVFGAGIMGRGIAVVLADAGHRVSLYD--------ARADVAREAAAAHP------N 48
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
+ A + + AV+ + + E V ENLE+K+ +F ++ ++T
Sbjct: 49 IEASDTIEA---------AVEGSSLLFEAVVENLEVKRDLFAEIERF-SESTPIASNTST 98
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+N+ +++++H NP VPLVE+VP+P T+P+V
Sbjct: 99 FTPSELAKNLCEPGRLVIAHFFNPAEVVPLVEVVPSPDTRPDV 141
>UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9;
Gammaproteobacteria|Rep: 3-hydroxyacyl CoA dehydrogenase
- Legionella pneumophila (strain Corby)
Length = 284
Score = 58.0 bits (134), Expect = 1e-07
Identities = 44/169 (26%), Positives = 71/169 (42%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 217
K K+ ++G+G +G LFA G+ VTL D ++ Q+ A I L L L
Sbjct: 2 KQTKLTLLGAGTMGSGITQLFAQYGFYVTLIDNLQSQLDKAKDTIAKNLHYLALTQNLES 61
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
+ + + T L +K + ++ E + EN E KK ++Q L I
Sbjct: 62 THSIETILASITFTTKLD-ELKQSEYIIENITENWERKKALYQVLKKECSATCILGVNTS 120
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ H +VI H +NP +P+VE++ T +KTR
Sbjct: 121 SIPITKIASLVDHPQRVIGVHFMNPAPMMPMVEVIKGYHTDELTIEKTR 169
>UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 387
Score = 57.2 bits (132), Expect = 2e-07
Identities = 39/161 (24%), Positives = 68/161 (42%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+K+ ++GSG +G A + GY V + DV ++ + + + +K + L G L
Sbjct: 7 KKIAVIGSGAMGHGIAQVCIMAGYTVVMVDVKQEFLDNGMKKVKESMDFLVGKGKLSAE- 65
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ D + + D AV D V E VPE ++LKKKVF ++ + +
Sbjct: 66 DKDRMMGQLSTSLDNKAAVADVQVVIEAVPEIMDLKKKVFADVSSAAPAEALLASNTSTM 125
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+ + + H NP + LVE++ T E
Sbjct: 126 SITEIATAVTKPERFLGMHFFNPVNRMKLVEVIFGEKTSAE 166
>UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus halodurans
Length = 287
Score = 56.8 bits (131), Expect = 3e-07
Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 4/169 (2%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ-LKTLEKDGLLRGNLN 226
VG+VG+G +G A L A G QV L D+ + Q+ DI Q + T + + +G ++
Sbjct: 6 VGVVGAGTMGSGIANLAAMSGLQVVLLDLDDNQL-----DIAWQKINTFMEKSVAKGKMS 60
Query: 227 ADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
E+ +K T + +A V E V ENL++KK+VF LD + ++TI
Sbjct: 61 EAEKEAALGRIKSTTTYE-ELAEADLVIEAVIENLDVKKEVFHTLDTCLANDTIIATNTS 119
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+V+ H NP + LVE+V T + + +
Sbjct: 120 SMSITEIAAATNRPDRVVGMHFFNPAQLMKLVEVVRGYQTSDDTVETVK 168
>UniRef50_Q5LVG3 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=2; Rhodobacteraceae|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 681
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/163 (29%), Positives = 74/163 (45%), Gaps = 2/163 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+V IVG GL+G AM G VT V+E+ A A + ++ L G+ RG ++
Sbjct: 288 RVAIVGGGLMGAGVAMACLGGGLSVT---VIERDAAAAQA-AQERVAGLVAAGVKRGKIS 343
Query: 227 ADEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
D Q + T D DA E V E+L++K+ VF +L V+ + I
Sbjct: 344 PDAQADMLARLATTDTYADASDADLAIEAVFEDLDVKRIVFADLAAVMRPDAILATNTSY 403
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ + A+ + H +P + + L+EIV P T PEV
Sbjct: 404 LDPQLVFAGIANPARCLGLHFFSPAHVMKLLEIVKTPDTAPEV 446
>UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Salinibacter ruber (strain DSM 13855)
Length = 719
Score = 56.8 bits (131), Expect = 3e-07
Identities = 44/161 (27%), Positives = 71/161 (44%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ VG++G+GL+G A + A G V L D + I + E G++
Sbjct: 319 DTVGVLGAGLMGSGIAQVSAQNGLDVVLTDQSLALAAEGKKAIWSAVTEQEDKGIIN-TF 377
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
D+ + V T D A ++ A V E VPE+L +K V ++ VVD +T+
Sbjct: 378 TRDQIVERVAPTADYA-PLQAADVVIEAVPEDLSIKHAVLSEVETVVDADTVLASNTSAL 436
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
E + ++V+ H +P +PL+EIV T E
Sbjct: 437 PISTIAEGVDDPSRVLGMHYFSPVPDIPLLEIVVTEETSDE 477
>UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase;
n=7; Bacteria|Rep: Beta-hydroxybutyryl-CoA dehydrogenase
- Polyangium cellulosum (Sorangium cellulosum)
Length = 293
Score = 56.8 bits (131), Expect = 3e-07
Identities = 45/162 (27%), Positives = 69/162 (42%), Gaps = 3/162 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
VG+VG+G++G A A G+ V L DV E + A I+ L+ + G A
Sbjct: 12 VGVVGAGVMGVGVAQSLAQTGHDVVLVDVSEAALARARMGIRNGLRAVTLFGSAEDKKRA 71
Query: 230 DEQ---FQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
+ + V T D + A FV E V E ++K++V+ L+ V I
Sbjct: 72 GDPKAVLERVAFTTDYG-RLAGADFVVENVTEKWDIKREVYARLEGVCRPEIIFAADTSA 130
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
K +QV+ H +NP P+VE++ T PE
Sbjct: 131 ISITRIGSVTKRPSQVVGMHFMNPVPLKPMVEVIRGFHTSPE 172
>UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 301
Score = 56.8 bits (131), Expect = 3e-07
Identities = 46/166 (27%), Positives = 71/166 (42%), Gaps = 1/166 (0%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
VG+VGSGL+G A + A GY V L D+ E + A+ I L L + G L +
Sbjct: 10 VGVVGSGLMGSGIAQVAAVAGYAVRLHDIEESALHRALTTIDESLHRLARKGKLS---TS 66
Query: 230 DEQFQCVKGTCDLAIA-VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
D + + T +A + D+ V E V E L++K+ VF L +V N +
Sbjct: 67 DVEAAKARITTTRRLADLADSDVVVEAVYEELDVKRVVFAELAAIVRPNVLLASNTTAIP 126
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ +V+ H +P + L EIV T + + R
Sbjct: 127 ITHIASGVSGPQRVVGMHFFSPVPVMQLCEIVRGLQTDDDTVARAR 172
>UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 322
Score = 56.4 bits (130), Expect = 4e-07
Identities = 42/162 (25%), Positives = 65/162 (40%), Gaps = 4/162 (2%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V +G G+IG W F G V L D A A I+ + G A
Sbjct: 13 VAAIGGGVIGGGWVAAFLGSGRAVRLHDPAP----GAEARIRAHVTQAWPQMAALGLARA 68
Query: 230 DEQFQCVKGTCDLAIAVKDAI----FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
D+ + G ++DA+ FVQE PE ++K+ +F LD +V + +
Sbjct: 69 DDDWT---GRLSFHETIEDAVEGTDFVQENTPERSDVKRALFAELDRLVPADVLVGSSTS 125
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKP 523
+ A+ ++ HP NP + +PLVE+ T P
Sbjct: 126 SLPISDLQAGLSTAARFVLGHPFNPVHLIPLVEVGGGDATDP 167
>UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 287
Score = 56.0 bits (129), Expect = 5e-07
Identities = 43/155 (27%), Positives = 68/155 (43%), Gaps = 1/155 (0%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGNLNAD 232
+VG+G +G AM+ A G+QV L DV + A +++ ++ + +EK ++ A
Sbjct: 6 VVGAGAMGSQIAMVCALAGHQVCLHDVDPAMLERADRELRDRMARQVEKGRRTADDVTAA 65
Query: 233 EQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXX 412
+ V + A A DA V E V E +E+K ++F LD + TI
Sbjct: 66 FERLRVADSLAAAAAAADADLVIEAVVERIEVKSELFAELDRLCPPATILASNSSSFVPS 125
Query: 413 XXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
+V H NP + VE+VP P T
Sbjct: 126 RLAAATGRADRVCNLHFFNPALVMACVEVVPGPET 160
>UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein 1;
n=2; Caenorhabditis|Rep: Hydroxy-acyl-coa dehydrogenase
protein 1 - Caenorhabditis elegans
Length = 299
Score = 56.0 bits (129), Expect = 5e-07
Identities = 44/168 (26%), Positives = 72/168 (42%), Gaps = 7/168 (4%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK---VQLKTLEKDGLLRGN 220
V I G+G++G A + GY V L+ EK++ +A IK +++ + +K +
Sbjct: 13 VAIFGAGMMGSGIAQVCLQAGYPVNLYGRSEKKLLEARETIKKNLIRVASKKKTDVPMEP 72
Query: 221 LNADE----QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 388
+E Q ++ D+ A +DA E V ENL+LK +FQ + N +
Sbjct: 73 AALEEIAQIQLDLLQIHTDIPSAAEDAAMAIEAVAENLDLKLDIFQTIQKTCPQNCMLIT 132
Query: 389 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVT 532
+++ A H NP + LVE+V T PE T
Sbjct: 133 NTSSLKLSQMLPVIQNPALFAGLHFFNPVPVMKLVEVVSTDETSPETT 180
>UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 344
Score = 56.0 bits (129), Expect = 5e-07
Identities = 47/163 (28%), Positives = 72/163 (44%), Gaps = 10/163 (6%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVG-YQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 220
+ + + G+GL+G A + A G + VTL DV +K + + I L + K + +
Sbjct: 42 QNITVFGAGLMGAGIAQVLAHKGKFNVTLSDVTDKALANGQTIISKSLGRIVKKSMAEAS 101
Query: 221 LNADEQFQCVKG-------TCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 379
A+EQ Q VKG T D AVKD V E + EN+ +KK +F LD + +
Sbjct: 102 --AEEQAQYVKGIVDSIKVTTDPEAAVKDTDLVIEAIIENVGIKKDLFGFLDGKAPKDAL 159
Query: 380 XXXXXXXXXXXXXXENMKHKAQVIVS--HPVNPPYYVPLVEIV 502
E + + Q + H NP + LVE+V
Sbjct: 160 FASNTSSLSITDVAEAVSAQRQELFGGFHAFNPVPQMKLVEVV 202
>UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=2; Aspergillus|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Aspergillus clavatus
Length = 307
Score = 56.0 bits (129), Expect = 5e-07
Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 2/162 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG--LLRGNL 223
V ++G G++GR M++A+ G+ V L+ EK A+A +K + L + LL G
Sbjct: 16 VAVIGGGVLGRRLCMMWAAAGHTVQLY---EKSPEVAVAALKYIHEALPQQASKLLLGK- 71
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A V L AV++A V E +PE L LK ++F LD + + I
Sbjct: 72 KAGHGIGHVSPASSLETAVQNAWMVIEAIPELLPLKIELFGQLDQLAPADCILATNSSSY 131
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
E + +A+V +H PP L EI+ +T P +
Sbjct: 132 KSREMLEKVARRARVCNAHYYMPPEQNHL-EIMTCGFTDPAI 172
>UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Sulfolobaceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Metallosphaera sedula DSM 5348
Length = 334
Score = 56.0 bits (129), Expect = 5e-07
Identities = 40/160 (25%), Positives = 80/160 (50%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KV ++GSG++G +FA G++VTL+DV E+ + A+ I+ L+ L++ G ++ +
Sbjct: 2 KVFVIGSGVMGSGIGQVFAMAGHEVTLYDVKEEALKKAMEGIRWSLQKLQEKGSVK---D 58
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
+ + + DL+ A +D + + E V E++++K V + + D+ I
Sbjct: 59 VESVLSRIFTSRDLSEA-RDHLVI-EAVFEDIKVKSDVLGRVSPLTDE--IIASNTSSLP 114
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+++ + + H NPP + LVE++ T E
Sbjct: 115 ITELSRAVRNPERFLGMHFFNPPVLMKLVEVIRGDNTSEE 154
>UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 517
Score = 55.6 bits (128), Expect = 7e-07
Identities = 41/155 (26%), Positives = 71/155 (45%), Gaps = 3/155 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
++G+VG+G +G A + A G+ V L+DV + + A+ ++ L+ G +
Sbjct: 3 RLGVVGAGTMGAGIAQVAAQSGFDVLLYDVDPEALARALGRVESDLQRQAARGRI----- 57
Query: 227 ADEQFQCVKGTCDLAIAVKD---AIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
D Q V G ++ D A FV E PE+LELK+++F+ LD + ++ +
Sbjct: 58 PDAQVAEVLGRITTTTSLGDFAAADFVIEAAPEDLELKRRLFERLDRLCREDVVLATNTS 117
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+V+ H NP + LVE+V
Sbjct: 118 SLSVTQIGALAGRADRVVGMHFFNPVPAMRLVEVV 152
>UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Burkholderiales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 304
Score = 55.6 bits (128), Expect = 7e-07
Identities = 45/164 (27%), Positives = 77/164 (46%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+V ++G+GL+G A+ F + + V ++D V Q +A+ + + LE G RG
Sbjct: 10 RVAVLGAGLMGHGIALAFMTSDFDVAIWDPVS-QAREAVRERIAE--HLELMGDPRG--- 63
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
D V+ L V+D V E PE++ K+++ + +D +V+ I
Sbjct: 64 VD-----VRVCSTLQDCVRDCDIVVEAAPESVSTKRELIREID-LVNSECIIASNTSVLR 117
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
E +V+ +H NPPY +PLVE+V T+ V K+
Sbjct: 118 ITEIAEGSADPGRVVGTHWWNPPYLMPLVEVVRGELTREGVAKQ 161
>UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome.
precursor; n=6; Pezizomycotina|Rep: Contig An11c0270,
complete genome. precursor - Aspergillus niger
Length = 599
Score = 55.6 bits (128), Expect = 7e-07
Identities = 46/164 (28%), Positives = 73/164 (44%), Gaps = 1/164 (0%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 220
S + ++G+G++GR A +FA+ GY V L+D A+ + LKT K +GN
Sbjct: 12 SRPLALLGAGVLGRRIACVFAAAGYNVNLYDPSLSAQQAALDYVTQNLKTYSK--FSKGN 69
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
+F + DL V DA V E VPE+L++K V LD + + I
Sbjct: 70 ----RRFGHCRAFSDLESTVSDAWLVIEAVPEHLQMKIDVMGELDKLAPVDCILASNSSS 125
Query: 401 XXXXXXXENM-KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
E + H+ ++ + P +VE++ T PEV
Sbjct: 126 FKSRFMLEKVGGHRRPLVCNMHFYMPPEKRVVELMTDGETWPEV 169
>UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation
multifunctional protein (MFP) [Includes: Enoyl-CoA
hydratase/3-2-trans-enoyl-CoA isomerase/3-
hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.3.3.8)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]; n=23; Magnoliophyta|Rep: Peroxisomal fatty
acid beta-oxidation multifunctional protein (MFP)
[Includes: Enoyl-CoA hydratase/3-2-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Oryza sativa subsp.
japonica (Rice)
Length = 726
Score = 55.6 bits (128), Expect = 7e-07
Identities = 43/163 (26%), Positives = 70/163 (42%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 217
K KV ++G GL+G A V L +V + + I L+ L K G L
Sbjct: 308 KIRKVAVIGGGLMGSGIATALLVSNTSVVLKEVNPQFLQRGQKMIAANLEGLVKRGSLTK 367
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
+ ++ +KG D + KD V E V E + LK+ +F +L+ V + I
Sbjct: 368 D-KMNKAMSLLKGALDYS-DFKDVDMVIEAVIEKIPLKQSIFSDLEKVCPPHCILATNTS 425
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
E + ++I +H +P + +PL+EIV T P+
Sbjct: 426 TIDLNVVGEKTNSQDRIIGAHFFSPAHIMPLLEIVRTEKTSPQ 468
>UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 309
Score = 55.2 bits (127), Expect = 9e-07
Identities = 40/163 (24%), Positives = 67/163 (41%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
++G+G++G A+ A G Q TL +A+ + + L + L L+ D
Sbjct: 8 VIGTGMMGPGIALTLALGGVQTTLLSRTPAGAERGVAEARRLGRVLVEQELAAA-LDLD- 65
Query: 236 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 415
+ G+ D ++ A V E PE + K+++F +D V + +
Sbjct: 66 ----IAGSTDFEYSIGQADIVIESGPEEMGWKQELFARMDRVARADAVLASNTSGLSVTA 121
Query: 416 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
QV+ +H NPP+ VPLVEI+ T P R
Sbjct: 122 IAAECARPEQVLATHFWNPPHLVPLVEIIQGRATSPAAAAAVR 164
>UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Kineococcus radiotolerans
SRS30216|Rep: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 681
Score = 54.4 bits (125), Expect = 2e-06
Identities = 42/161 (26%), Positives = 74/161 (45%), Gaps = 1/161 (0%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLR 214
K VG+VG+GL+ A+L + V L DV ++ + ++ + L + G +
Sbjct: 317 KVTSVGVVGAGLMASQLALLLLHRLQVPVVLTDVSPDRVEKGVGFVREGVAELLRKGRVS 376
Query: 215 GNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
+ A+ V G+ D + A+ DA FV E V E L +K+ V + L+ ++ + +
Sbjct: 377 PD-TANRLSASVSGSVDKS-ALADADFVVEAVFEELAVKQDVLRELEPLLRPDAVIATNT 434
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
++H + + H NP +PLVE+V P T
Sbjct: 435 SSLSVTAMASVLEHPQRFVGFHFFNPVAVLPLVEVVRTPET 475
>UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 765
Score = 54.4 bits (125), Expect = 2e-06
Identities = 43/164 (26%), Positives = 78/164 (47%), Gaps = 2/164 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
EKV ++G+G++G A A+ G +V L DV + A AD ++ + ++ G +
Sbjct: 6 EKVAVLGAGVMGAGIAAHLANAGVRVVLLDVDK-----AAADAGIR-RARDEGGFMDPAF 59
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A + DL++ + DA ++ E +PE L LK+ +++ L + +I
Sbjct: 60 AA--RIATGSTVRDLSL-LADADWIVEALPERLALKQSLYRQLQGIRKPGSILSSNTSTI 116
Query: 404 XXXXXXENMK--HKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
M A +++H NPP + L+E+V P T+PE+
Sbjct: 117 PLAALVGGMAGDFAADFLITHFFNPPRRMRLLELVAGPATRPEI 160
>UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 722
Score = 54.0 bits (124), Expect = 2e-06
Identities = 40/166 (24%), Positives = 73/166 (43%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ VG+VG GL+G A G QV L ++ ++ + + I+ L ++ + G + +
Sbjct: 305 KSVGVVGGGLMGSGIATACLLAGIQVVLKEIKQEFLDAGVGRIQSNLTSMVRKGRMTED- 363
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A + VK T + V E V ENL LK+K+F L+ + + I
Sbjct: 364 KARQLMSLVKPTLTDQ-DFRQCDMVIEAVIENLPLKQKIFCELERICKPDCILSTNTSTI 422
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
MK+ +++ +H +P + + L EI+ T ++ T
Sbjct: 423 DITKIAAKMKNPERIVGAHFFSPAHVMQLFEIIRTDATPAQILVDT 468
>UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5;
Trichocomaceae|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 338
Score = 54.0 bits (124), Expect = 2e-06
Identities = 29/87 (33%), Positives = 42/87 (48%)
Frame = +2
Query: 266 LAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQ 445
L A A VQE PEN++ K+ + ++ V + M+ K +
Sbjct: 93 LESACASATIVQEQGPENVDWKQSAWARIEAVAPPSAHLWTSTSGIAASIQQAKMQDKTR 152
Query: 446 VIVSHPVNPPYYVPLVEIVPAPWTKPE 526
++V HP NPP +PL+EIVPAP T E
Sbjct: 153 LLVVHPFNPPNIMPLLEIVPAPGTSAE 179
>UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 687
Score = 53.6 bits (123), Expect = 3e-06
Identities = 44/155 (28%), Positives = 68/155 (43%), Gaps = 3/155 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
K+ IVG G +G A SVG V L + DAIA + + TL GL RG L+
Sbjct: 284 KIAIVGGGTMGAGIAYACLSVGLPVVLLET----DADAIARAQHNIDTLIGAGLKRGRLD 339
Query: 227 ADEQFQCVKGTCDLA---IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
D ++ L A DA V E E++++KK +F LD V +T+
Sbjct: 340 -DSGAAALRDRLTLTEDYAAASDATLVIEAAFESMDVKKDIFAKLDAAVSPDTVLATNTS 398
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ + ++++ H P + + L+EIV
Sbjct: 399 YLDVDVLAASTRDPSRILGLHFFAPAHIMRLLEIV 433
>UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A277A UniRef100 entry -
Xenopus tropicalis
Length = 666
Score = 53.2 bits (122), Expect = 4e-06
Identities = 42/161 (26%), Positives = 69/161 (42%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KVGIVG+G +G AM FA+VG + +V ++ + + ++ + G L
Sbjct: 292 KVGIVGAGTMGGGIAMNFANVGIPTVVVEVNDETLQRGLGLVRRNYEASAAKGRLTAEQV 351
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
A + ++G D A A+ + V E V EN+ LK+ + L V I
Sbjct: 352 AG-RMALLQGALDYA-ALAECDLVIEAVFENMALKQDICAKLGAVAKPGAIIATNTSTLD 409
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
A V+ H +P + + L+E+V T P+V
Sbjct: 410 VDVLARATGRSADVVGMHFFSPAHVMRLLEVVRGAATAPDV 450
>UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 289
Score = 53.2 bits (122), Expect = 4e-06
Identities = 37/112 (33%), Positives = 57/112 (50%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
++V I G+G +GRS + A G +V L+DV E + A + V++ + G L
Sbjct: 7 KRVLIAGAGTMGRSIGLSCAVRGCEVILYDVKEDALEAARRAMAVKIDKMVPAGALTPEA 66
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 379
A+ + T DLA A DA V E VPE+ ++K + F+ L V + TI
Sbjct: 67 -AESIKANITTTTDLAAAGADADLVSESVPEDPDIKGEFFEKLHGVCPERTI 117
>UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subunit
precursor; n=1; Euglena gracilis|Rep:
L-3-hydroxyacyl-CoA dehydrogenase subunit precursor -
Euglena gracilis
Length = 320
Score = 53.2 bits (122), Expect = 4e-06
Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 7/169 (4%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLE----KDG---L 208
VG+VG G +G A + A+ GY+V D+ ++ I ++ L + KDG
Sbjct: 25 VGVVGMGAMGHGIAQMTAAAGYKVVAVDIDANMLSKGIKAVEDSLSKVAAKAVKDGKADK 84
Query: 209 LRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 388
NA + + + D+ A+ V E + E+L +KKK F +L V N I
Sbjct: 85 ATAEKNAADVRSRITTSGDIG-ALSSCDLVIESIIEDLNIKKKFFADLGKVAGANAILAS 143
Query: 389 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
E + + H NP + LVE++ TK +V K
Sbjct: 144 NTSSFPITQLGEASGRTSNFLGLHFFNPVQMMKLVEVIKTKDTKEDVYK 192
>UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 310
Score = 52.8 bits (121), Expect = 5e-06
Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 1/166 (0%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V ++G+GL+G A A G +V L+D Q + ++ +Q +K+ L R + A
Sbjct: 8 VAVIGAGLMGTCIAGELAYHGARVNLYD-RSAQAMEKSKEMLIQ----QKEQLKREEVMA 62
Query: 230 DEQFQCVKGTCD-LAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
F C+ L AV ++ + E ENLE+KK VF+++ N +
Sbjct: 63 TSDFIGTVAFCESLEEAVVNSGLIFEATIENLEVKKSVFKSISQFCRTNAVIATNTLALD 122
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
E++ + + + + P Y +P VEI T PE +K +
Sbjct: 123 TSVVAEHVTNPERCLGIRFLYPVYSIPEVEITLGSQTSPETIQKVQ 168
>UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep:
Enoyl-CoA hydratase - Rhodopseudomonas palustris
Length = 699
Score = 52.4 bits (120), Expect = 7e-06
Identities = 42/160 (26%), Positives = 68/160 (42%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+V I+G+G +G AM FA+ G VTL + E+Q+ + ++ + G L +
Sbjct: 297 RVAIIGAGTMGGGIAMSFANAGIPVTLIETGEEQLKRGLGIMQKNWEATAARGGLPPDAP 356
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
A ++ + G L VKDA + E V E + +KK+VF +D +
Sbjct: 357 A-KRMALITGLVGLE-NVKDADLIIEAVFETMAVKKEVFTAVDAHAKPGAVLASNTSYLS 414
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
K V+ H +P + L EIV T P+
Sbjct: 415 IDEIAATTKRPQDVLGMHFFSPANVMKLCEIVRGAKTAPD 454
>UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=14; Staphylococcus|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Staphylococcus aureus subsp. aureus JH9
Length = 753
Score = 52.4 bits (120), Expect = 7e-06
Identities = 46/164 (28%), Positives = 72/164 (43%), Gaps = 3/164 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFD-VVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
KV ++G+G +G A LF + G +V L D VV+K + IA K K +K L +L
Sbjct: 5 KVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLIAK-KSYDKITDKKRPLLFDL 63
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
N G D + DA E V E++E+K V+Q + ++ +
Sbjct: 64 NLVSHL--TYGNFDDDLVNDDADLYIEAVKEDIEIKHAVWQQVLQHAKEDALFATNTSGI 121
Query: 404 XXXXXXE--NMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ N K + + H NPP + LVE++P TK +
Sbjct: 122 PINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSHTKESI 165
>UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 304
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
EK+G+VG GL+G FA G +V DV E+++ + IK L++ + +G +
Sbjct: 3 EKIGVVGFGLMGTQITQFFAQQGLEVVAIDVSEERLRKGMEAIKAGRFGLQR-LVEKGKI 61
Query: 224 NADEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVD 367
+E + T A+KD V E V E++ LK KV + +D V D
Sbjct: 62 TEEEMNAVLSRISTSTSHSALKDCDLVIEAVFEDVNLKLKVLREIDAVTD 111
>UniRef50_Q5LVD0 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=6; Rhodobacterales|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 698
Score = 52.0 bits (119), Expect = 9e-06
Identities = 44/163 (26%), Positives = 67/163 (41%), Gaps = 3/163 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+G++G G +G A G VT+ ++ + A I+ L L RG L A
Sbjct: 292 IGVIGGGTMGAGIATAALLSGLSVTMLEMTPEAAEAAKGRIEGNL----SGALKRGKLTA 347
Query: 230 DEQFQCVKGTCDLAI---AVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
+ LAI A+ DA V E V E++E+KK+VF LD V +
Sbjct: 348 QQFDNLTTKALTLAIDYDALADADLVIEAVFEDMEVKKQVFTKLDAVCKPGAVLASNTSY 407
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
V+ H +P + + L+E+V A T P+V
Sbjct: 408 LDINQIAAVTSRPQDVLGLHFFSPAHVMKLLEVVIADQTAPDV 450
>UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=54;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 284
Score = 52.0 bits (119), Expect = 9e-06
Identities = 42/155 (27%), Positives = 66/155 (42%), Gaps = 2/155 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 220
E VG+VG+G +G A A G V + DV + + IA +K L + + KD L
Sbjct: 4 EIVGVVGAGTMGNGIAQTAAVAGLNVVMIDVSDAALEKGIATLKGSLDRLVSKDKL--DA 61
Query: 221 LNADEQFQCVKGTCDLA-IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
D + + D A +A D + E EN+ELK ++ + ++ V I
Sbjct: 62 ATRDAALARITTSTDYAKLAAADIVI--EAATENVELKGRILKQIEAVARAEAIIATNTS 119
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ A+ + H NP +PLVEI+
Sbjct: 120 SISITALAAPLADPARFVGMHFFNPVPLMPLVEII 154
>UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB3;
n=1; Mycobacterium ulcerans Agy99|Rep:
3-hydroxybutyryl-CoA dehydrogenase FadB3 - Mycobacterium
ulcerans (strain Agy99)
Length = 294
Score = 52.0 bits (119), Expect = 9e-06
Identities = 40/148 (27%), Positives = 67/148 (45%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 217
+S V ++G+G +GR A++FAS G V ++ +Q A + L L +D RG
Sbjct: 13 RSRPVAVIGAGTLGRRIALMFASRGGTVRIYARRAEQRAQATQYVADNLPKLLQD---RG 69
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
+ V T LA A++ A E VPE LE+K ++ +D +TI
Sbjct: 70 F----GEVGSVTATDCLATALEGAWLAVESVPEKLEIKTALWGQIDQAAPPDTIFATNSS 125
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYY 481
+N++ K ++ +H PP +
Sbjct: 126 SFPSRLMADNVRDKTRLCNTHFYMPPQF 153
>UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 52.0 bits (119), Expect = 9e-06
Identities = 38/155 (24%), Positives = 65/155 (41%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 220
+ K+ +VGSG +G A + A G +V L DV + + + DGL
Sbjct: 19 ARKIAVVGSGYMGGGIAQVLALGGARVALADVSAEVAQSNYDRLLAESDQFVADGLFPAG 78
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
+ + Q + D+ AV DA F++E VPE + +K + + + I
Sbjct: 79 -STEILKQNLWAARDIEEAVADADFIEEAVPEIIAIKHQTLARISAAARPDAIIGSNTST 137
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVP 505
E + + + + H NP ++P VEI+P
Sbjct: 138 ISIADLSEPVTNPERFLGVHFSNPSPFIPGVEIIP 172
>UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase; n=18;
Bacteria|Rep: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase - Deinococcus
radiodurans
Length = 708
Score = 51.6 bits (118), Expect = 1e-05
Identities = 39/162 (24%), Positives = 70/162 (43%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ GI+G+G +G AM F +VG VT+ + ++ + + I+ + K G + +
Sbjct: 308 KSAGIIGAGTMGGGIAMNFLNVGIPVTIVETSQEALDRGLGVIRKNYENTAKKGRMTQD- 366
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ +++ + T + + A + E V EN+++KK +F LD + I
Sbjct: 367 DVEKRMGLLTPTLKME-DLAGADIIIEAVFENMDVKKDIFTRLDKIAKPGAILASNTSTL 425
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
QVI H +P + L+EIV A T V
Sbjct: 426 DVNEIASVTGRPEQVIGLHFFSPANVMKLLEIVRADKTSDSV 467
>UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=34;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 298
Score = 51.6 bits (118), Expect = 1e-05
Identities = 47/171 (27%), Positives = 79/171 (46%), Gaps = 4/171 (2%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 217
K ++VG++G+G++G A + A V +F+ + A A L++L++ G+ G
Sbjct: 5 KIQRVGVIGAGIMGAGIAEVCARAHVDVLVFEQTREL---AAAGRSRILRSLDR-GVSSG 60
Query: 218 NLNADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVV-DDNTIXX 385
+ E+ Q ++ T DL D V E V E+ ++K ++F LD VV D N +
Sbjct: 61 KITEREREQAAWRLRFTSDLG-DFADRQLVVEAVVEDEKVKSEIFTELDQVVTDPNAVLA 119
Query: 386 XXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
K +VI H NP +PLVE+V T V+++
Sbjct: 120 SNTSSIPIMKLGIATKSPERVIGMHFFNPVPVLPLVELVTTLKTSKSVSER 170
>UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Frankia sp. (strain CcI3)
Length = 624
Score = 51.2 bits (117), Expect = 2e-05
Identities = 43/164 (26%), Positives = 70/164 (42%), Gaps = 3/164 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
VG+VGSG + A + A G+ V L E+ + +A I+ L + RG L+
Sbjct: 345 VGVVGSGTMAGGIAEVLARSGHDVLLRARSERTLAATLAKIESSLAA----SVARGRLSD 400
Query: 230 DEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
++ V+GT DL + + E V E+L +K+++F +LD + +
Sbjct: 401 ADRLAALARVRGTTDLG-ELGHCELLLEAVVEDLAVKRELFADLDKIAAPGAVLATTTSS 459
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVT 532
VI H NP + L+E+VP T +VT
Sbjct: 460 LPVIECAMATSRPRDVIGMHWFNPAPAMKLIEVVPTVLTGDDVT 503
Score = 43.2 bits (97), Expect = 0.004
Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 4/168 (2%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK-TLEKDGLLR 214
+ +VG+VG G +G A + A G +V V + DA+A + +++ +L++ G
Sbjct: 37 RHRRVGVVGLGTMGAGIAEVLAKAGLEV----VGIARDADALARSRARVEHSLDRAG-RH 91
Query: 215 GNLNADEQFQCVKGTCDLA---IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 385
G L+ D + V L AV D V E + E + K+ +F LD + T+
Sbjct: 92 GKLD-DATREAVLARMRLGTELAAVADCELVIEAIDERMSAKQALFARLDEICPPATVFL 150
Query: 386 XXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+V+ +H NP + LVE+V T P V
Sbjct: 151 TNTSSLSVTELAAGTARPERVLGTHWFNPAPVMRLVEVVRTVVTDPTV 198
>UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:
PlmT8 - Streptomyces sp. HK803
Length = 571
Score = 51.2 bits (117), Expect = 2e-05
Identities = 42/162 (25%), Positives = 65/162 (40%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 220
+ ++G+VGSG + A A GY TL E + +A+A ++ L + G L
Sbjct: 290 ARRIGVVGSGTMATGIAQACARAGYPTTLVARSEVRAKEALATVENSLNRAVQRGRLTPE 349
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
+ + G L AV V E V E++++K+ VF+ LD V T+
Sbjct: 350 -QLTSSMESLTGVSRLE-AVAACDLVVEAVVEDIDVKRTVFRELDAVCGAQTVLATSTSS 407
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
V+ H NP + LVE+V T E
Sbjct: 408 LPVIECAMATGRPEAVVGMHFFNPAPVMKLVEVVRTALTSRE 449
>UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA
dehydrogenase and acyl-CoA-binding protein; n=11;
Francisella tularensis|Rep: Fusion product of
3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding
protein - Francisella tularensis subsp. tularensis
(strain FSC 198)
Length = 898
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 2/167 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+K+ ++G+G +G A FA+ + V LFD+ +Q A I+ L L K
Sbjct: 118 DKIAVLGAGTMGAQIAAHFANAKFPVVLFDLKSQQ-GSANVIIEDSLAKLTKLNPAPFGS 176
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
++ D + D + E V E +++K+ ++ + + + +N I
Sbjct: 177 KDSIKYITPANYEDNLELLADCDLIIEAVAERIDIKESLYTKISSHIKENAILASNTSGL 236
Query: 404 XXXXXXENMKHKAQVIVS--HPVNPPYYVPLVEIVPAPWTKPEVTKK 538
+ + +V H NPP Y+PLVE++P T E+ K
Sbjct: 237 SITKLAQVLPENLKVNFCGVHFFNPPRYMPLVELIPHADTNSEILDK 283
>UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 517
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/161 (22%), Positives = 70/161 (43%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V ++G+G++GR A L A+ G V L D ++ ++ A+ + L G + A
Sbjct: 11 VRVIGTGVMGRGIAQLAAAAGLTVELADARQEAVSAAVDHVGEMFGKLVGKGRMSAE-EA 69
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
D ++ D V E V E+L+ K+++F L+ V + +
Sbjct: 70 DAATARLRPVGDPLAPADSCDLVVEAVREDLDTKRELFAGLEEVCPRHAVLATNTSSLSV 129
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVT 532
+ +++I H NP + LVE++P T+ +++
Sbjct: 130 TAIGAALADPSRLIGLHFFNPVPLMKLVEVIPGARTRQDLS 170
>UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 275
Score = 51.2 bits (117), Expect = 2e-05
Identities = 45/154 (29%), Positives = 68/154 (44%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 220
S + +VG G +GR A+ + G++VTL DV E + A A + + RG
Sbjct: 2 STSMVVVGGGTMGRGIAIAALATGFEVTLVDVAEDVLDRAQARVSEHFARHPQPD--RGV 59
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
L+ T LA +++ A V E VPE L LK ++FQ L T+
Sbjct: 60 LHT---------TTSLAGSLETAEVVIEAVPEILPLKTQIFQQLRG-APPGTLLVSNTST 109
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
E ++V+ H NP + +PLVE+V
Sbjct: 110 MSISALAEACGGSSRVVGMHFFNPAHRMPLVEVV 143
>UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=13;
Clostridia|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Clostridium difficile
Length = 281
Score = 51.2 bits (117), Expect = 2e-05
Identities = 42/157 (26%), Positives = 65/157 (41%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
K+ ++GSG +G FAS G+ V L + I +A + L L G
Sbjct: 2 KLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTKGKWMKATK 61
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
A E V T + +KD + E E++ +KK VF+ LD + ++TI
Sbjct: 62 A-EILSHVSSTTNYE-DLKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILATNTSSLS 119
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
+ K +VI H NP + LVE++ T
Sbjct: 120 ITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLT 156
>UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme; n=3; Bordetella|Rep: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme - Bordetella pertussis
Length = 705
Score = 50.8 bits (116), Expect = 2e-05
Identities = 36/156 (23%), Positives = 67/156 (42%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
+VG+G +GR A+ A G +V DV + + A+ I+ ++L G + A +
Sbjct: 308 VVGAGTMGRGIAIALADAGLRVRFIDVEQASLDRALEAIRAHYRSLAARGRMT-EAAARD 366
Query: 236 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 415
+ D+ A +A V E E+L +K+ +F+ LD++V +
Sbjct: 367 AVARISPASDMQ-AAAEADVVVEAAFEDLAIKQAIFRQLDSIVRPGAVLATNTSTLDVDA 425
Query: 416 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKP 523
+ V+ +H +P + L+E+V T P
Sbjct: 426 IAAATRRPQDVVGTHFFSPANVMRLLEVVRGARTAP 461
>UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 733
Score = 50.8 bits (116), Expect = 2e-05
Identities = 45/166 (27%), Positives = 75/166 (45%), Gaps = 8/166 (4%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT----LEKDG-- 205
E+V I+G+G++G A + A GYQV L D+ ++ + +A + QL+ L+ G
Sbjct: 333 ERVAILGAGMMGAGLAYICADAGYQVVLKDINQEALDKGVAHFEAQLRKRKRHLDDAGRQ 392
Query: 206 LLRGNLNADEQFQCV--KGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 379
+R L + + G DL I +A+F ENL+LK +V + + + + I
Sbjct: 393 AIRDRLTPSLELSALSDNGGTDLII---EAVF------ENLDLKHRVTRETEPTLSADGI 443
Query: 380 XXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
+ H + I H +P +PL+EIV P T
Sbjct: 444 WASNTSAIPIGDLAKVSAHADRFIGLHYFSPVEVMPLLEIVVGPET 489
>UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Lactobacillus reuteri|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Lactobacillus reuteri F275
Length = 294
Score = 50.8 bits (116), Expect = 2e-05
Identities = 42/169 (24%), Positives = 77/169 (45%), Gaps = 4/169 (2%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLF----DVVEKQITDAIADIKVQLKTLEKDGLL 211
+ + I G+G++G A A G+ V+++ D E++I +D + L +K+
Sbjct: 2 KNIMIAGAGVLGSQIAYQTALSGFNVSVYNHHIDTAERRIKALKSDYERDLHLTDKE--F 59
Query: 212 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 391
+ LN + T D+A AVKDA + E +PE+LELK++ ++ + + + TI
Sbjct: 60 QQGLNNIKVI-----TDDVATAVKDADLMIEALPESLELKEQFYEEVSELAPEKTIFASN 114
Query: 392 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
+ + H N + +VEI+ T PEV ++
Sbjct: 115 SSTFIPSQLAPYTDRPEKFLNMHFANQIWKFNVVEIMGTSQTSPEVIEE 163
>UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Marinomonas sp. MED121|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Marinomonas sp. MED121
Length = 545
Score = 50.8 bits (116), Expect = 2e-05
Identities = 35/153 (22%), Positives = 67/153 (43%), Gaps = 2/153 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+G+VG+G +G A + + G++V L+D Q +A K + L + +G +
Sbjct: 17 IGVVGAGAMGAGIAQVASQAGHKVFLYD----QNEEASFRAKESISLLLNKKVAKGTITR 72
Query: 230 DEQFQCVKGTCDL--AIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ C+ L +K A + E + E LE+K+ +F+ L+ + I
Sbjct: 73 EHYDTCIANIIPLHSLDELKSADLIIEAIVETLEIKQSLFRALELICKPECILASNTSSI 132
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+K+ + + H NP +PLVE++
Sbjct: 133 SITAIASCLKYPERFLGLHFFNPAPVMPLVEVI 165
>UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2;
Alphaproteobacteria|Rep: Acetoacetyl-CoA reductase -
Rhodobacterales bacterium HTCC2150
Length = 780
Score = 50.8 bits (116), Expect = 2e-05
Identities = 36/165 (21%), Positives = 77/165 (46%), Gaps = 3/165 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKV-QLKTLEKDGLLRGN 220
+++ ++G+G +G A A+ G++V L D+ K + + + V +L + L+
Sbjct: 7 KRIAVIGAGTMGSGIAGQIANAGHEVLLLDLPGKNSRNEVTENAVTRLLKSDPPALMHKK 66
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
A + ++ D + + ++ E + E L++KK ++Q L++V+ +
Sbjct: 67 RAALIKVGNIEDDFD---KLAECDWIVEAIVERLDIKKALYQRLNDVISPECVVTSNTST 123
Query: 401 XXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
E+M +A+ ++H NP Y+ L+E+V T P V
Sbjct: 124 IPIKLLVEDMPQDFRARFAITHYFNPVRYMRLLELVRGADTNPAV 168
>UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Comamonas testosteroni KF-1
Length = 706
Score = 50.8 bits (116), Expect = 2e-05
Identities = 43/155 (27%), Positives = 71/155 (45%), Gaps = 3/155 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+VGI+G+G +G AM FA+ G V L + + + +A I+ + + RG L
Sbjct: 307 RVGILGAGTMGGGIAMAFANAGIPVVLCEREQAALDRGMAMIERNYQI----SVSRGGLT 362
Query: 227 AD---EQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
A+ E+ Q ++ T DL+ A + V E V E++ +K+ VF LD + TI
Sbjct: 363 AEAVKERMQHIQQTLDLS-AFAEVDLVIEAVFEDMAIKRDVFVQLDRICRKGTILATNTS 421
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ VI H +P + L+E+V
Sbjct: 422 RLNINEIAAVTQRPEDVIGLHFFSPANVMKLLEVV 456
>UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit,
mitochondrial-like protein; n=6; Trypanosomatidae|Rep:
Trifunctional enzyme alpha subunit, mitochondrial-like
protein - Leishmania major
Length = 726
Score = 50.4 bits (115), Expect = 3e-05
Identities = 36/163 (22%), Positives = 71/163 (43%), Gaps = 3/163 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGNL 223
+VG++G+G++G FA V + D+ E+ + I +++ + + + + ++ L
Sbjct: 309 RVGVIGAGVMGSGIVHYFAKNNIPVAVKDLTEESVKQGITNVRAEFERAVRRKRMVTAEL 368
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNL--DNVVDDNTIXXXXXX 397
D + V G + +DA + E E +++KKKV Q L D ++ ++
Sbjct: 369 --DGKMALVTGGTTNEV-FRDADVIVEAAVEVMDIKKKVIQQLEKDGILHSKSLFATNTS 425
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
K ++ H NP +PLVE++ T E
Sbjct: 426 SLSLTEMQTVAKCPHNIVGMHFFNPVSKMPLVEVIKGKSTSTE 468
>UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 278
Score = 50.0 bits (114), Expect = 4e-05
Identities = 32/110 (29%), Positives = 53/110 (48%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+ ++G+G +GRS A A G++ L D++ + A I+ +L G + A
Sbjct: 7 IAVIGAGTMGRSIAQAAAVGGFRTILEDILPNALRKAEDAIRAELGRAVSTGSVEQR-EA 65
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 379
D ++ +L A +DA V E VP+ LE K ++F LD V T+
Sbjct: 66 DAALARIEYASNLEDAARDADMVIEAVPDELESKLEIFVLLDKVCRPETM 115
>UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Shewanella woodyi ATCC 51908|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Shewanella woodyi ATCC 51908
Length = 696
Score = 50.0 bits (114), Expect = 4e-05
Identities = 43/177 (24%), Positives = 76/177 (42%)
Frame = +2
Query: 5 QTLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL 184
Q L +S VG+VG+G +G A F G + + E+ + + +++
Sbjct: 293 QKLATSTSSTRTINTVGVVGAGNMGVGIARCFIDAGMDLIWIEQTEEALLRGMDNLRKGY 352
Query: 185 KTLEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVV 364
++ G + + D++ Q VKG+ + + V E E+LE+KK +F+ LD
Sbjct: 353 QSKITKGHMTEQ-DLDDKMQLVKGST-VYDRLAPCDLVVEAAFEDLEVKKIIFKALDQHC 410
Query: 365 DDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
D+ I + QV+ H +P + + L+EIV A T +V K
Sbjct: 411 KDSAILATNTSYLDINSIAKVTSRPDQVVGLHFFSPAHVMKLIEIVRAENTADDVIK 467
>UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=5; Gammaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Serratia proteamaculans 568
Length = 506
Score = 50.0 bits (114), Expect = 4e-05
Identities = 37/160 (23%), Positives = 68/160 (42%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+V ++G+G +G A + A+ G+QV LFD+ A+ + +L+ G + +
Sbjct: 9 RVAVIGAGTMGIGIAQVAAAAGHQVQLFDIAASAARQALGALAQRLRQRVAAG--KADAT 66
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
E + ++ D+ V E V E L +K+ +F+ L+ + T+
Sbjct: 67 TTEALLARIQPAESLNSLADSGLVIEAVAEKLAIKQSLFRELEALCSPATLFASNTSSLS 126
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
++H ++ H NP + LVEIV T E
Sbjct: 127 ITAIAGALQHPQRLAGLHFFNPAPLMKLVEIVSGLDTSTE 166
>UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Caulobacter sp. K31|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Caulobacter sp. K31
Length = 296
Score = 49.6 bits (113), Expect = 5e-05
Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 3/174 (1%)
Frame = +2
Query: 29 SKFKSE-KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG 205
S F E K+G+VG+GL+G A++FA G V L D + A+A + L G
Sbjct: 10 SPFAPELKIGVVGAGLMGAEIALVFALGGMDVLLHDRDAAALEKALARLSALLDRGVSRG 69
Query: 206 LLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 385
L A + ++ DL+ D V E V E+LE+K +V LD + +
Sbjct: 70 LYTEGRRA-TALENIRLAPDLS-RFGDRDLVTEAVFESLEVKGQVLAALDEACPEACVIA 127
Query: 386 XXXXXXXXXXXXENM--KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
+ + + + + +H +P + LVE+VPA T PE T
Sbjct: 128 SNTSTLPISTLGAALSPERRPRFLGAHYFSPVSRMLLVEVVPAFETSPETVAWT 181
>UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=32;
Proteobacteria|Rep: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE -
Brucella melitensis
Length = 565
Score = 49.2 bits (112), Expect = 6e-05
Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 2/162 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+ IVG+G++G A + A G +FD E ++ + L L + +G ++A
Sbjct: 48 IAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASLDRLASTLAKLAE----KGKISA 103
Query: 230 DEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
++ V C + D V E + E L+ K+ +F L+ VV N I
Sbjct: 104 EDAQTAVSRIEICSSIQELADCDLVVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSL 163
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+H +V H NP + +VE++ T P V
Sbjct: 164 SVTSIARVCRHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAV 205
>UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=4; Brucella|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 501
Score = 49.2 bits (112), Expect = 6e-05
Identities = 40/159 (25%), Positives = 68/159 (42%), Gaps = 2/159 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KV I+GSG++G A A+ G V LFD Q+ D + K+ L + + RG L
Sbjct: 8 KVAIIGSGVMGAGIAETMAAGGIDVLLFD----QMADKASAAKLALSHRLQSRVERGKLG 63
Query: 227 ADEQFQCVKGTCDL--AIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
AD Q ++ + + A V E + ENL +KK + L+ ++ +
Sbjct: 64 ADRAAQILERIVPVQQLDEIVSADLVVEAIVENLTVKKDLVAALEAILPRQAVIATNTSS 123
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
+ K+ ++ H NP + +VE++ T
Sbjct: 124 LSVTAIAASAKYPERIAGFHFFNPVPLMRVVEVIKGALT 162
>UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16;
Bacillaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 795
Score = 49.2 bits (112), Expect = 6e-05
Identities = 45/177 (25%), Positives = 75/177 (42%), Gaps = 16/177 (9%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIA---------DIKVQLKTLEK 199
+ ++GSG++G A A+VG L D+V +++T ++ +L
Sbjct: 7 RAAVLGSGVMGSGIAAHLANVGIPTLLLDIVPRELTKEEEAKGWTLEHKQVRNRLANQAL 66
Query: 200 DGLLRGN----LNADEQFQCVKGTC-DLAIAVKDAIFVQECVPENLELKKKVFQNLDNVV 364
+ LL+ ++ D G D + + ++ E V E LE+KK+VF +D V
Sbjct: 67 ERLLKQKPAPLMSKDNIALIETGNFEDDFHRLAEVDWIIEAVVEKLEVKKEVFARVDEVR 126
Query: 365 DDNTIXXXXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
TI E K + +H NPP Y+ L+EI+P T P+V
Sbjct: 127 TPGTIVSSNTSGISIAAMAEGRSDDFKKHFLGTHFFNPPRYLKLLEIIPTEHTDPDV 183
>UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 849
Score = 49.2 bits (112), Expect = 6e-05
Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 2/176 (1%)
Frame = +2
Query: 8 TLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK 187
T+R S F KV ++G+G++G A + V LFD+ K+ +K ++
Sbjct: 33 TIRRHPVSNFLIRKVAVLGAGVMGAQIAAHLINARVPVLLFDLPAKEGPKNAIALKA-IE 91
Query: 188 TLEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVD 367
+L+K + D ++ D + + V E + E ++ K +++ + +
Sbjct: 92 SLKKLSPAPFGVKDDAKYLEAANYEDDIAKLAECDVVIEAIAERMDWKHDLYKKVAPHIA 151
Query: 368 DNTIXXXXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
N I E K++ H NPP Y+ LVE++P T+PE+
Sbjct: 152 PNAIFATNTSGLSITKLSEGFSDELKSRFCGVHFFNPPRYMHLVELIPTAHTRPEI 207
>UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 801
Score = 49.2 bits (112), Expect = 6e-05
Identities = 43/176 (24%), Positives = 74/176 (42%), Gaps = 10/176 (5%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEK---DGL 208
K +K ++GSG++G A L AS G + L D+V +TD + K D +
Sbjct: 4 KIKKAAVIGSGVMGGGIAALLASAGVETLLLDIVPFDLTDEQKKDPAARNRIVKFGYDTI 63
Query: 209 LRGNLNA-----DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDN 373
+ A D + D + D ++ E V ENL++K+++F+ ++ V
Sbjct: 64 MMSRPAALMHSSDAALISIGNLEDDFDKLADCDWIVEVVVENLKIKQQLFKRIEPVRKKG 123
Query: 374 TIXXXXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
+I E + K + +H NP Y+ L+EI+ T EV +
Sbjct: 124 SIISSNTSGIPLKAMSEGLSSDFKQHFLGTHFFNPVRYMHLLEIIKGEETSEEVLR 179
>UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 312
Score = 49.2 bits (112), Expect = 6e-05
Identities = 36/151 (23%), Positives = 73/151 (48%), Gaps = 1/151 (0%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ-LKTLEKDGLLRGNLN 226
+ ++G+G +G + A+LFA+ G++VTL D + A + + L+ LE+ GL +
Sbjct: 5 IAVIGAGTMGAAIALLFANAGFEVTLVDKSRGALRRAEDRHRGESLEELEEAGLRK---- 60
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
D + T +L + D F+ E + E L K ++F+ ++ ++ +
Sbjct: 61 QDNPASLITYTTELRVYECD--FIVEAIVERLRDKIELFRKIEE-INSPAVLATNTSSFM 117
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEI 499
++ + ++ + H NPP +PLVE+
Sbjct: 118 PSEIARHLANPERLTLFHFSNPPILMPLVEV 148
>UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=5; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacter sphaeroides ATCC 17025
Length = 673
Score = 48.8 bits (111), Expect = 8e-05
Identities = 36/153 (23%), Positives = 65/153 (42%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
++G++G G +G A A+ G + TL + + I ++ + G L
Sbjct: 292 RIGVIGGGTMGSGIAAAIAAAGLEATLAETGPDALEAGIKRVRAIFEAQVTRG-LTDRAG 350
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
A ++ V GT L + D V E V E+L +K++VF++L + + I
Sbjct: 351 AADRLARVSGTVGLG-PLADCDLVIEAVFEDLAVKRRVFEDLTRLCRPDAILATNTSYLD 409
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVP 505
+ + + I H +P + L+EIVP
Sbjct: 410 PERIVAGLPNPDRFIALHFFSPAQVMKLLEIVP 442
>UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified
Gammaproteobacteria (miscellaneous)|Rep: Enoyl-CoA
hydratase - marine gamma proteobacterium HTCC2080
Length = 699
Score = 48.8 bits (111), Expect = 8e-05
Identities = 39/151 (25%), Positives = 60/151 (39%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
VGI+G+G +G AM FA G VTL D+ ++ + + I K G L +
Sbjct: 296 VGIIGAGTMGGGIAMCFAQAGIAVTLVDMTDEAVKGGLEKIAKNYAISVKKGRL--TVAQ 353
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
+ T + + V E V ENLE+KK+VF LD + +
Sbjct: 354 TDAILANITTSSSFDDLANVDMVIEAVFENLEVKKEVFGKLDVICKPGAVLASNTSYQSI 413
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
V+ H +P + L+E+V
Sbjct: 414 DAIAAATSRPESVLGMHFFSPANVMKLLEVV 444
>UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Acidobacteria bacterium
Ellin345|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Acidobacteria bacterium (strain
Ellin345)
Length = 806
Score = 48.4 bits (110), Expect = 1e-04
Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 5/166 (3%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLE--KDGLLRG 217
EKV ++G+G +G A FA+ G LFD+V D A K+ L+ K
Sbjct: 6 EKVAVLGAGTMGARIAAHFANAGIPSYLFDIVPPD-ADGPARNKIAAAGLDAAKKSKPAA 64
Query: 218 NLNAD-EQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
+ D + V D + + ++ E V ENLELK+ + + ++ V ++
Sbjct: 65 FFHPDLAKLVTVGNFEDDLKKLGECDWIIEAVVENLELKRALLKKVEAVRKPGSLITTNT 124
Query: 395 XXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
E + +H NPP Y+ L+E++P P T P+
Sbjct: 125 SGLPVSKISEGFSEDFRRNWFGTHFFNPPRYMRLLELIPTPDTDPK 170
>UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 296
Score = 48.4 bits (110), Expect = 1e-04
Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 3/167 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V ++G+G +G A + A G++ L+D+ E + I + +K L G L+A
Sbjct: 12 VAVLGAGTMGSGIATVMARAGHRTILYDINEANLERGIDTVH---GFFDKSVRL-GKLDA 67
Query: 230 DEQFQCVKGTCDLAIAVKDAI---FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
Q K + + +KD V E V E+L LKK+ F LD++V T+
Sbjct: 68 TAG-QAAKDSLSGSTELKDLAPCDVVVEAVFEDLSLKKETFGRLDDIVPPTTLFHTNTST 126
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
+ + +V+ +H NP + LVE+ T K T
Sbjct: 127 LSVTGIASGSRLRERVVGTHYCNPAPLMKLVEVANGRHTADWAHKAT 173
>UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 284
Score = 48.0 bits (109), Expect = 1e-04
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 1/168 (0%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ VG+VG G +G A +FA++G V + + +++ A+ + L + G L G++
Sbjct: 7 KNVGVVGGGRMGAGIAQVFATLGSTVIIAESGDREA--AVKRVSDGLDRAHERGKL-GDV 63
Query: 224 NADEQFQCVKGTCDLAIAVKDAI-FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
+ V T A+ A+ V E VPE ++LK V ++ V T+
Sbjct: 64 DPATILGRV-STVAAPDALPPALDLVVEAVPELVDLKLSVLSLVEKTVSPTTVIASNTSS 122
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ A++I H NP LVEIV AP T V +K R
Sbjct: 123 ISIAELGSALGDPARLIGMHFFNPVPASSLVEIVRAPATDAGVVEKVR 170
>UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=6; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Roseiflexus sp. RS-1
Length = 807
Score = 48.0 bits (109), Expect = 1e-04
Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 17/179 (9%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLE-KDGLLRGN 220
+KV ++G+G +G A + G QV L D V +T + L++ E ++ +R
Sbjct: 5 KKVAVIGAGTMGGGIAAHCINAGLQVVLLDTVPSSLTPEEEKRGLTLESKEVRNRFVRAG 64
Query: 221 L----NA------DEQF--QCVKGTC--DLAIAVKDAIFVQECVPENLELKKKVFQNLDN 358
L NA D Q + V G DLA+ + DA ++ E + E LE K+ + + ++
Sbjct: 65 LERIKNARPAALFDPQSISRIVTGNVEDDLAL-IADADWIVEAIIEQLEPKRALMEKIEQ 123
Query: 359 VVDDNTIXXXXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
V +I + + +H NPP Y+ L+E++P P T P+V
Sbjct: 124 VRKPGSIVSSNTSGIPIAAIAAGRSDDFRRHFLGTHFFNPPRYLYLLEVIPTPDTDPQV 182
>UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 283
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/151 (23%), Positives = 61/151 (40%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+ ++G G IG S A A G+ V + + E + A + L
Sbjct: 6 IAVIGGGNIGSSLAFDCALRGHNVVVVEKDEPSCEQSRARVLETAGYAPLFSPLAKGKKP 65
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
+ ++ + +L A+ D FV E +PEN+ELK+ ++ + + N +
Sbjct: 66 QDILDNIRWSNELG-AISDCAFVVENIPENIELKQALYTRMAEFIAPNAVLAANTSCIPI 124
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
K AQVI H +NP Y VE++
Sbjct: 125 TKLGSFHKTSAQVIGVHFMNPVYLKHTVEVI 155
>UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Actinosynnema pretiosum subsp. auranticum
Length = 341
Score = 47.6 bits (108), Expect = 2e-04
Identities = 37/154 (24%), Positives = 62/154 (40%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
++G+G++G L S G V L D ++ A AD++ L+T + G+ G L
Sbjct: 62 VLGAGVMGCGITALALSRGLPVLLVDPDADRLDAARADVRAHLRTAQLLGVAAGPLGE-- 119
Query: 236 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 415
+ D ++ + V E V E+ E K K + V T
Sbjct: 120 ----LTTATDTG-GPREVVAVVEAVTEDAETKAKALTGVCATVPPGTPLVSNTSSIPMGE 174
Query: 416 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
+ ++ +H +NPPY +P VE+ P T
Sbjct: 175 LAPALPRPGDLVGAHFMNPPYLIPAVEVARGPLT 208
>UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=10; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 509
Score = 47.2 bits (107), Expect = 2e-04
Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 2/162 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+ IVG+G++G A + A G +FD E A A + +L + +G ++A
Sbjct: 8 IAIVGAGVMGTGIAQIAAQAGLVTQIFDARE----GAAAASRDRLASTLAKLAEKGKISA 63
Query: 230 DEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
++ V C + D V E + E L+ K+ +F L+ VV N I
Sbjct: 64 EDAQTAVSRIEICSSIQELADCDLVVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSL 123
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+H +V H NP + +VE++ T P V
Sbjct: 124 SVTSIARVCRHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAV 165
>UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2;
Bordetella|Rep: Putative enoyl-CoA isomerase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 694
Score = 47.2 bits (107), Expect = 2e-04
Identities = 39/162 (24%), Positives = 66/162 (40%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
E+V +VG+G +G + A G V DV ++ A + + L L
Sbjct: 288 EQVAVVGAGTMGTGIVICLADAGLPVIWHDVDADRLAQGRAQVCQHFERLAARKRLTSR- 346
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A+++ V T ++A + A E V E++ +K VF+ LD V+ I
Sbjct: 347 QAEQRVAAVATTGEMA-GIAQADLAIEAVFEDMAVKCAVFRELDRVLKPGAILGTNTSTL 405
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ + V+ H +P +PL+EIV T +V
Sbjct: 406 DVDRIAHSTRRPQDVVGLHFFSPAPVMPLLEIVRGAATHADV 447
>UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Dinoroseobacter shibae DFL 12|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Dinoroseobacter shibae DFL 12
Length = 391
Score = 46.8 bits (106), Expect = 3e-04
Identities = 42/150 (28%), Positives = 63/150 (42%), Gaps = 4/150 (2%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGL-LRGNL 223
I+GSG IG WA F G+ V +FD + ++T I + L L L G L
Sbjct: 7 IIGSGRIGSGWAARFLLFGWHVRVFDADPGAQARLTQVIEAARTSLLGLYDTPLPPPGRL 66
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ +A AV A++VQE VPE+L LK++V + + I
Sbjct: 67 SQHG---------SIAEAVAGAVWVQESVPEDLSLKREVVREV-QAHGPEAIVASAASDI 116
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLV 493
E +V+++ V P Y +P V
Sbjct: 117 PLEALREGAARPERVVIARAVAPVYLLPPV 146
>UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;
n=9; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - Coxiella burnetii
Length = 642
Score = 46.4 bits (105), Expect = 4e-04
Identities = 39/171 (22%), Positives = 80/171 (46%), Gaps = 1/171 (0%)
Frame = +2
Query: 29 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDG 205
+++ +++ ++G+G++G A A G +VTL D ++I AI + K L+
Sbjct: 269 TRYLPQQIHVIGAGVMGGDIAAWCALRGIRVTLHDKSAEKIAPAIKRAHALYEKKLKIPR 328
Query: 206 LLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 385
L++ + D V+GT VK A + E V E++++K++V ++ + I
Sbjct: 329 LIQAAM--DRLEPDVEGT-----GVKKADLIIEAVFEDIKVKQEVLSAIEPQLKPEAILA 381
Query: 386 XXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
+K+ +++ H NP +PLVE+ + T ++ +K
Sbjct: 382 TNTSSLSLDELSSVLKNPERLVAIHFFNPVAKLPLVEVASSQQTSADIAEK 432
>UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit
FadJ; n=2; Cystobacterineae|Rep: Fatty oxidation
complex, alpha subunit FadJ - Myxococcus xanthus (strain
DK 1622)
Length = 746
Score = 46.4 bits (105), Expect = 4e-04
Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 2/165 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASV-GYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRG 217
+KV ++G GL+G A + + + G V + D + + A+ ++ L + +++ L R
Sbjct: 350 KKVAVLGGGLMGGGIAYVTSVLQGVPVRVKDKDDAGVGRAMKQVQSILDERVKRRSLTRR 409
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
A V D + K A V E V E+L+LK ++ ++ V D TI
Sbjct: 410 EATAKSAL--VTAGTDYS-GFKSADLVIEAVFEDLKLKHRIIAEVEAVTGDQTIFASNTS 466
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVT 532
+ + AQVI H +P + +PL+EI+ T VT
Sbjct: 467 SIPITELAKGSRRPAQVIGMHYFSPVHKMPLLEIITHAGTADWVT 511
>UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=20; Proteobacteria|Rep:
Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 797
Score = 46.0 bits (104), Expect = 6e-04
Identities = 42/168 (25%), Positives = 68/168 (40%), Gaps = 3/168 (1%)
Frame = +2
Query: 29 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQ-ITDAIADIKVQLKTLEKDG 205
SK KV ++G+G++G A A+ V LFD+ K + + D + T
Sbjct: 2 SKLIIRKVAVLGAGVMGAQIAAHCANADVPVVLFDLPAKDGPPNRVVDRAIGGLTKLDPA 61
Query: 206 LLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 385
L + A DL ++D V E + E LE K+ ++ + + I
Sbjct: 62 PLAAAVRASH-IDAANYDSDLE-RLRDCDLVIEAIAEKLEWKRDLYAKAAPYLRPDAIFA 119
Query: 386 XXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKP 523
E + +++ H NPP Y+ LVE++PAP T P
Sbjct: 120 SNTSGLSIATLAEGLPEALRSRFCGVHFFNPPRYMALVELIPAPATDP 167
>UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 681
Score = 46.0 bits (104), Expect = 6e-04
Identities = 42/162 (25%), Positives = 67/162 (41%), Gaps = 2/162 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQLKTL-EKDGLLRGN 220
KVGIVG+GL+ A LF + V + D+ + + + + L EK L G
Sbjct: 318 KVGIVGAGLMASQLAQLFIERLEVPVVMKDISPEALEKGCGQVVEGFRRLGEKGKLTEG- 376
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
A V GT D D FV E V E + +KK+V L+ ++ + +
Sbjct: 377 -KARHLAGLVSGTLDFR-DFSDCDFVIEAVFEEMAVKKQVLGELEPLLRPDAVIATNTSS 434
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
++ +++ H NP +PLVE++ T E
Sbjct: 435 LSVTEMASVLRVPGRMLGFHFFNPVAVLPLVEVIRTAQTSGE 476
>UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=16;
Gammaproteobacteria|Rep: Fatty acid oxidation complex
subunit alpha [Includes: Enoyl-CoA
hydratase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 731
Score = 46.0 bits (104), Expect = 6e-04
Identities = 42/166 (25%), Positives = 68/166 (40%), Gaps = 1/166 (0%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGY-QVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+VGI+G GL+G A + A+ G V + D+ E+ I A+ QL T
Sbjct: 324 RVGILGGGLMGGGIASVTATRGQLPVRIKDINEQGINHALK-YNWQLLTKRVQSKRMKPT 382
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ G+ D + A V E V E+L LK+++ +++ +TI
Sbjct: 383 ERQRLMTLISGSTDYR-GFEHADIVIEAVFEDLALKRQMITEIEDHAAPHTIFASNTSSL 441
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
E + V+ H +P +PLVE++P T E T
Sbjct: 442 PIHQIAEGARRPQLVVGLHYFSPVDKMPLVEVIPHAHTSAETVATT 487
>UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 710
Score = 45.6 bits (103), Expect = 8e-04
Identities = 40/159 (25%), Positives = 64/159 (40%)
Frame = +2
Query: 26 ASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG 205
AS E++G+VG G +G A+ G VT+ + E + A ++ L G
Sbjct: 299 ASARPVERIGVVGGGTMGAGIAVSALDAGLPVTMIERDEASLARGRAHVEKVYDGLVAKG 358
Query: 206 LLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXX 385
+ +A + GT A+A D + E V E++ +KK VF L V +
Sbjct: 359 RMTPAAHAARLARFKGGTSYDALAQADVVI--EAVFEDMAVKKAVFAELARVCKPGAVLA 416
Query: 386 XXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
++ A VI H +P + L+EIV
Sbjct: 417 TNTSYLDIDELAASIDRPADVIGLHFFSPANVMKLLEIV 455
>UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Psychromonas|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychromonas ingrahamii
(strain 37)
Length = 724
Score = 45.6 bits (103), Expect = 8e-04
Identities = 38/160 (23%), Positives = 64/160 (40%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+ ++G+G++G A LF+ V L D+ ++ + L+K + N
Sbjct: 326 QAAVLGAGVMGGGIAWLFSKNEIPVRLKDIEWDAVSKGYQTAALYYGQLKKVHKINEN-K 384
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
+ + GT + K V E V ENLE+KK V + ++ + I
Sbjct: 385 IRVKMNYIAGTVNYN-GFKRIDLVVEAVSENLEVKKTVLEEVEAQLSKQAILASNTSSLS 443
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
N++ I H NP +PLVEI+P T +
Sbjct: 444 ITEMAVNLQRPENFIGMHFFNPVNRMPLVEIIPGEKTSQQ 483
>UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:
Dehydrogenase - Fusarium sporotrichioides
Length = 285
Score = 45.6 bits (103), Expect = 8e-04
Identities = 34/110 (30%), Positives = 53/110 (48%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V ++G G++GR A +A+ GY V + D +Q A+ + D +RG++ A
Sbjct: 14 VAVLGGGVLGRRIACGWAASGYDVIIRDPSHEQRVAAVEYCNTSMSKY-PDSNVRGSIQA 72
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 379
E DL AV A V E VPE L +K F +L+ + ++TI
Sbjct: 73 VE---------DLPEAVAKAWLVIETVPEKLPIKIATFTDLERLTSEDTI 113
>UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=5; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Xanthobacter sp. (strain Py2)
Length = 789
Score = 45.2 bits (102), Expect = 0.001
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 4/167 (2%)
Frame = +2
Query: 35 FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQIT--DAIADIKVQLKTLEKDGL 208
F +KV ++G+G++G A A+ G +V L D+V + +AIA+ V+ K L+ D
Sbjct: 16 FDIKKVAVIGAGVMGAGIAAHVANAGIEVLLLDIVPEGAANRNAIAEKAVE-KLLKADPA 74
Query: 209 LRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 388
+ A + D + ++ E V E L++K+ ++ ++ +
Sbjct: 75 AFMSKRA-AKLVTAGNIEDNLSDLASCDWIVEAVIERLDIKQALYAKIEAARRPGSAVSS 133
Query: 389 XXXXXXXXXXXENM--KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKP 523
+ + +++H NPP Y+ L+EIV P T P
Sbjct: 134 NTSTIPLGDLTAGLPESFRRDFLITHFFNPPRYMRLLEIVAGPETNP 180
>UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 723
Score = 45.2 bits (102), Expect = 0.001
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 1/165 (0%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 220
+ +VG++G GL+G + + A+ G V + + + A+ ++ L K +
Sbjct: 328 ARRVGVLGGGLMGSGISFVTANAGIPVRIRERDDAAAGKALGSVRALLDERVKRRSI-DR 386
Query: 221 LNADEQFQCVKGTCDLA-IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
L DE+ + V T D + A D + E V E+L LK+++ + + V+ I
Sbjct: 387 LERDERMRLVTATTDWSGYAAVDVLI--EAVFEDLALKQEMVRAFE-AVNPTGIFASNTS 443
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVT 532
E H V+ H +P +PL+EI+ T E T
Sbjct: 444 SIPITKIAEASAHPETVLGMHYFSPVQKMPLLEIIVTEKTSKEAT 488
>UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=23; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 733
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVE------KQITDAIAD--IKVQLKTLEK 199
+KVGI+G+G++G A + A G +V L D + K ++ + D +K T EK
Sbjct: 328 KKVGIIGAGMMGAGIAYVSALAGIEVVLIDAAQDSADRGKAYSEGLLDKGMKRGKVTEEK 387
Query: 200 DGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNT 376
+ G + A + + G CDL + +A+F V + K + N D + NT
Sbjct: 388 KAKVLGQITATTDYDALNG-CDLIV---EAVFEDPKVKAEVTAKAEAAMNADGIFATNT 442
>UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=7; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 723
Score = 44.8 bits (101), Expect = 0.001
Identities = 41/158 (25%), Positives = 69/158 (43%), Gaps = 3/158 (1%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 217
K KVGI+G+G++G A + A G V L D I A K L+K + RG
Sbjct: 321 KVSKVGILGAGMMGAGIAYVSAKAGIDVVLLDT---SIEAAEKGKDYSSKLLDK-AIARG 376
Query: 218 NLNADEQFQCVKGTCDLAIA---VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 388
+ +++ Q + + A ++D + E V E++++K +N + V+ + I
Sbjct: 377 R-STEQKKQALLDKINTTTAYDDLEDCDLIIEAVFEDIDIKAACTRNTEAVIAETAIYAS 435
Query: 389 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ K Q I H +P +PLVEI+
Sbjct: 436 NTSTLPITELAKASKRPNQFIGLHFFSPVDKMPLVEII 473
>UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit
FadB; n=1; Blastopirellula marina DSM 3645|Rep: Fatty
oxidation complex, alpha subunit FadB - Blastopirellula
marina DSM 3645
Length = 724
Score = 44.8 bits (101), Expect = 0.001
Identities = 35/158 (22%), Positives = 67/158 (42%), Gaps = 1/158 (0%)
Frame = +2
Query: 32 KFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLL 211
K K E V ++G+G++G A G TL D + + +A + ++ ++D
Sbjct: 314 KTKIESVSVIGAGIMGAGIAAASIRRGILTTLSDANAEALRRGVAGV-LEEAAYDRDAGK 372
Query: 212 RGNLNADEQFQCVKGTC-DLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 388
+ A E + + D +A + E + ENLE+K+K++ L+ + D+ I
Sbjct: 373 KTIAKAVEGAAMLNASISDSEVAASKLVI--EAIVENLEVKRKIYARLEPQLADDAILAS 430
Query: 389 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
N+ + + H NP + LVE++
Sbjct: 431 NTSTLPITQLAANLAKPERFVGIHFFNPVRKMKLVEVI 468
>UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=104; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 736
Score = 44.8 bits (101), Expect = 0.001
Identities = 47/164 (28%), Positives = 73/164 (44%), Gaps = 8/164 (4%)
Frame = +2
Query: 35 FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDV-VE-----KQITDAIAD--IKVQLKT 190
+++ KVG++G+G++G A A G +V L DV VE K ++ + D I T
Sbjct: 322 YRAVKVGVLGAGMMGAGIAYSCARSGMEVVLKDVAVESAEKGKAYSEKLLDKAIAKGRST 381
Query: 191 LEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDD 370
EK L G + A + G CDL I +A+F E+ LK++VF + VD
Sbjct: 382 EEKKAELLGRITATADAADLAG-CDLVI---EAVF------EDPSLKQQVFAEIAPYVDQ 431
Query: 371 NTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ + + A I H +P +PLVEI+
Sbjct: 432 DALLCSNTSTLPITELASGVDRPADFIGLHFFSPVDKMPLVEII 475
>UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Geobacter lovleyi SZ|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor - Geobacter
lovleyi SZ
Length = 285
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/158 (22%), Positives = 60/158 (37%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+G+ G+G +G A L A G++V L+ + DA I+ L L + GL+
Sbjct: 8 IGVAGAGSMGAGIAQLAAMAGFRVRLYARHASALADAAGRIETSLAKLHEKGLIG---EE 64
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
+ C +A+ D V E + E + K ++ L V+ I
Sbjct: 65 PTVIRARISNCHEPVALSDCDLVIEAIAEQMAAKCELLAELGAVLGKEAILASSTSSLSI 124
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKP 523
+ I H +NP + LVE++ T P
Sbjct: 125 TALGAASGIPQRFIGMHFMNPVPLMELVELIAGSETSP 162
>UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein ech-8 - Caenorhabditis elegans
Length = 437
Score = 44.8 bits (101), Expect = 0.001
Identities = 32/153 (20%), Positives = 68/153 (44%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ V ++G G +GR A+ F G++ L +V K ++++ K EK +
Sbjct: 40 KSVAVIGGGTMGRGIAIAFCLSGFETYLVEVNNKAAEFCKNELEITYKR-EKAFRRLNDS 98
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
++ + ++ T D + + + E V E+++LKK++F LD + + I
Sbjct: 99 KVEKLRKNLQITTDFQ-KLNNCDLIVEAVFEDMKLKKELFTKLDKICKPSCIFGTNTSSL 157
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
++ +V+ H NP + +VE++
Sbjct: 158 DLNEMSSVLRDPTKVVGIHFFNPANLIRMVEVI 190
>UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Picrophilus torridus|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Picrophilus torridus
Length = 273
Score = 44.8 bits (101), Expect = 0.001
Identities = 37/166 (22%), Positives = 78/166 (46%), Gaps = 2/166 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+V ++G+G +G A +FA ++V L DV + + I+ L+ ++ G ++ +
Sbjct: 2 RVTVIGAGTMGSGIAEVFALNNHEVLLSDVSNDILNNGRKKIEASLEKFKEKGRIK---S 58
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNL--DNVVDDNTIXXXXXXX 400
++ + + D+ D +++ E V E +++K+ V + D+++ NT
Sbjct: 59 VEDVLEKISMNTDINAQESD-LYI-EAVLERIDVKRDVLSRIRSDSIIATNT------SS 110
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
+ +++ + I H NPP + L+EIV T E TK+
Sbjct: 111 ISITYLSKFVRNPEKFIGMHFFNPPPIMSLIEIVRGNSTSDETTKR 156
>UniRef50_Q5P607 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=2; Proteobacteria|Rep: Fusion
of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 671
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/167 (22%), Positives = 68/167 (40%), Gaps = 2/167 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASV--GYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
V ++G+G IG S ++TL DV + + A+ G +
Sbjct: 21 VAVIGAGTIGPDIGYYLKSALPELKLTLVDVSQAALDRALQRFHDYAAKAVAKGKM-SEA 79
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A + GT D + DA +V E EN+ LK+++F +++ VV + +
Sbjct: 80 EARAVTANLAGTLDYG-DIADADWVLEAATENIALKRRIFADVEAVVRPDALITSNTSSL 138
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
++H + V+H P + P+VE+V +P V + R
Sbjct: 139 PAAQIFAELRHPERATVTHFFAPAWRNPVVEVVRWEKAEPAVVEYLR 185
>UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Mesorhizobium sp. (strain BNC1)
Length = 677
Score = 44.4 bits (100), Expect = 0.002
Identities = 39/157 (24%), Positives = 67/157 (42%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
++G++G+G +G A+ + G V L D + +T A A +K L LE+ G L+
Sbjct: 287 RLGVIGAGTMGVGLAVSLLAAGKSVVLIDKDDLALTRASAAVKSGLARLERGGKLKE--A 344
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
D + + +L+ AV++ V E V E+ E+K V +L + +
Sbjct: 345 PDAALARLVASKELS-AVENCEVVIEAVVESFEVKSAVLSDLHARLSPGAMVVSNTSYLD 403
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
+ + H P + LVE+VP P T
Sbjct: 404 IAELARASGRPDRFLGLHFFAPVPVMTLVEVVPLPET 440
>UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;
n=4; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - gamma proteobacterium HTCC2207
Length = 718
Score = 44.0 bits (99), Expect = 0.002
Identities = 43/172 (25%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Frame = +2
Query: 23 MASKFKSEKV-GIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEK 199
+ASK K G++G+G++G A A GY V + D+ + + I + K L K
Sbjct: 310 LASKLPEIKTAGVIGAGIMGGGIAYQNAIRGYSVVMKDINQPALDLGIQEAN---KLLAK 366
Query: 200 DGLLRGNLNADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDD 370
G+ RG L ++ Q +K + + + + V E V E +KK V ++ ++D+
Sbjct: 367 -GVKRGKLTEEKAGQILSLIKPSLEDSDVAPCNMLV-EAVVELESVKKMVLPAVEALLDN 424
Query: 371 NTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+ + E+++ H NP + +PLVEI+ T E
Sbjct: 425 SAVITSNTSTISINRLAESLERPQNFCGMHFFNPVHAMPLVEIIRGENTSDE 476
>UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Solibacter usitatus
Ellin6076|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Solibacter usitatus (strain
Ellin6076)
Length = 778
Score = 44.0 bits (99), Expect = 0.002
Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 2/163 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+V ++G+G +G A FA+ G+ V L D+V A +++ K + +
Sbjct: 7 RVAVLGAGTMGARIAAHFANAGFPVDLLDLVLPDKPQRNALALAGIESAAKQRPVGFFTD 66
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
A + D V ++ E V ENLE+K+ ++Q + + I
Sbjct: 67 AAKTLITPGNFEDDLGRVGRCEWIVEAVAENLEIKRALWQRVAALRAPGAILSTNTSGIP 126
Query: 407 XXXXXENM--KHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ + + +H NPP Y+ L E++P T PEV
Sbjct: 127 LAQISAGFDSEFRRHFLGTHFFNPPRYLHLAEVIPGAETNPEV 169
>UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 659
Score = 43.6 bits (98), Expect = 0.003
Identities = 39/159 (24%), Positives = 66/159 (41%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+GI G+GL+G A+ + GY V ++ + A I ++ G L A
Sbjct: 297 IGIAGTGLMGSGIAVASLAAGYTVIGYETTAEAAAKGHARITDMIQKAVDTGRLSTEA-A 355
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
D Q + + D+A A+ DA V E V ++ +K +F+ LD ++ TI
Sbjct: 356 DAQRSKLSVSADMA-ALADADLVIEAVFDDFTVKASLFRELDALLPPATILATNTSYLNP 414
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+V+ H +P + L+E+V T E
Sbjct: 415 DELAAVTNRTDRVLGLHFFSPANIMRLLEVVRCAETSDE 453
>UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
related protein; n=3; Thermoplasmatales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase related protein -
Thermoplasma acidophilum
Length = 314
Score = 43.6 bits (98), Expect = 0.003
Identities = 21/77 (27%), Positives = 38/77 (49%)
Frame = +2
Query: 296 VQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPP 475
V E EN ++K ++F ++ ++ ++ I +K ++ H NPP
Sbjct: 115 VIEAAFENQDVKNRIFSDISDL-SEHAIIASNTSSLSITEMSSRLKRPENALILHFFNPP 173
Query: 476 YYVPLVEIVPAPWTKPE 526
Y +PLVE+VP+ +T E
Sbjct: 174 YLLPLVEVVPSLYTSDE 190
>UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family protein; n=1; Lentisphaera
araneosa HTCC2155|Rep: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family protein - Lentisphaera araneosa
HTCC2155
Length = 762
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/165 (24%), Positives = 77/165 (46%), Gaps = 4/165 (2%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEK-QITDAIADIKVQLKTLEKDGLLR 214
K + + ++GSG++G A FA+ G+ V L D+ AI++ V+ K L+ +
Sbjct: 3 KIKHIAVLGSGVMGSQIAAHFANCGFSVALLDLTSAGPKPSAISEGAVK-KLLKINPSPL 61
Query: 215 GNLNADEQFQCVKGTCDLAIA-VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 391
+ + E G D + + +A + E V E+L +K+ ++ + V + I
Sbjct: 62 YSPSVIENI--FPGNFDDHLEHLDEADLIIEAVIEDLAIKQNLWSQICKYVKADAILATN 119
Query: 392 XXXXXXXXXXENMKHKA--QVIVSHPVNPPYYVPLVEIVPAPWTK 520
+N+ +K+ + + H NPP Y L+E++P P T+
Sbjct: 120 TSGLPLKDITKNLSNKSLKRFLGVHFFNPPRYQKLLELIPGPKTQ 164
>UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 313
Score = 43.2 bits (97), Expect = 0.004
Identities = 24/82 (29%), Positives = 36/82 (43%)
Frame = +2
Query: 284 DAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHP 463
D V ECVPE L++K+++F L+ + +K A++I H
Sbjct: 79 DVDLVIECVPERLDIKQELFAKLEKYAKPEAVLASNSTSFPISEIASGLKTAARMIGLHF 138
Query: 464 VNPPYYVPLVEIVPAPWTKPEV 529
P + VP VE+V T P V
Sbjct: 139 FMPAHLVPCVEVVYGEKTSPMV 160
>UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 281
Score = 43.2 bits (97), Expect = 0.004
Identities = 46/157 (29%), Positives = 72/157 (45%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
KV ++G+GL+GR A+ AS ++V L DV EK + A I +L L K
Sbjct: 2 KVFVIGAGLMGRGIAIAIAS-KHEVVLQDVSEKALEAAREQIPEEL--LSK--------- 49
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
++ T L VKD V E V E+L K +V + ++ + N
Sbjct: 50 -------IEFTTTLE-KVKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSVIS 99
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
E + ++ + H +NPP+ +PLVEIV + +T
Sbjct: 100 VDDIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFT 136
>UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=65; Bacteria|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Bacillus subtilis
Length = 287
Score = 43.2 bits (97), Expect = 0.004
Identities = 37/162 (22%), Positives = 67/162 (41%), Gaps = 1/162 (0%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 220
+++ + G+G +G A A G+ V ++DV + + +K QL + EK
Sbjct: 4 KQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKRLKKQLARDAEKGKRTETE 63
Query: 221 LNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
+ + + T + A + A V E + EN+ K ++F+ LD + +TI
Sbjct: 64 VKSVINRISISQTLEEA---EHADIVIEAIAENMAAKTEMFKTLDRICPPHTILASNTSS 120
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+VI H +NP + LVE++ T E
Sbjct: 121 LPITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATSEE 162
>UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Sphingomonas sp. SKA58
Length = 722
Score = 42.7 bits (96), Expect = 0.005
Identities = 44/172 (25%), Positives = 73/172 (42%), Gaps = 3/172 (1%)
Frame = +2
Query: 32 KFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFD---VVEKQITDAIADIKVQLKTLEKD 202
KF+++KVG++G+G++G A + A+ G V L D ++ D A KV K +EK
Sbjct: 310 KFEAKKVGVLGAGMMGAGIAFVSANAGIDVVLIDRDTATAQKGKDYSA--KVLGKLVEKG 367
Query: 203 GLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIX 382
L + AD + T D A+ + V E V E+ +K + + + V+ I
Sbjct: 368 KLTQD--KADAVLARITPTDDFAL-LDGCDMVVEAVFEDTAIKAETTKKAEAVLPAQAIF 424
Query: 383 XXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
+ + Q I H +P + LVE++ T E K
Sbjct: 425 ASNTSTLPISQLAQASRSPDQFIGLHFFSPVDRMGLVEVIMGKQTSKETLAK 476
>UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep:
Blr2428 protein - Bradyrhizobium japonicum
Length = 715
Score = 42.3 bits (95), Expect = 0.007
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 1/152 (0%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDGLLRGNLN 226
V ++G+G +G A A G +V+L D+ + I A+ ++ K + K +R L
Sbjct: 343 VHVIGAGAMGGDIAAWCAGQGLRVSLADMKAEPIAGAVKRAAELYGKIIRKPTEVRDAL- 401
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
D + G V++A V E VPE LELK+KV+ L+ + I
Sbjct: 402 -DRLIPDMDGE-----GVRNADLVIEAVPEKLELKQKVYAGLEPKMKPGAILATNTSSIP 455
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ +++ H NP + LVE+V
Sbjct: 456 LQDLRTTLARPDRLVGLHFFNPVSRLQLVEVV 487
>UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Lactobacillales|Rep: Dihydrolipoyl dehydrogenase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 469
Score = 42.3 bits (95), Expect = 0.007
Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGL 208
E + I+G G+IG WA L S+G VT+ + +++ + + A I +L K LE+ G+
Sbjct: 183 ESIAIIGGGVIGVEWASLLNSLGVNVTIIEFLDRLLINESATISKELKKRLEQRGI 238
>UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 287
Score = 42.3 bits (95), Expect = 0.007
Identities = 37/166 (22%), Positives = 68/166 (40%), Gaps = 1/166 (0%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
VG++G+G +G + A GY+V D E+ + A ++ L++ + G L A
Sbjct: 5 VGVLGTGTMGAGIVQVAARAGYRVVACDASEEALGKARRYVRSGLESFARRGAL-SEEEA 63
Query: 230 DEQFQCVKGTCDL-AIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
+ V+ T + +A +A+ E + E + KK+ F LD ++ + +
Sbjct: 64 EAALGRVRWTTAMEELAGSEAVI--EAIVERVGPKKEAFAALDALLPPDALLLTNTSSIS 121
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+V +H PP VE+V T E ++ R
Sbjct: 122 ITELASATGRPERVCGAHFFTPPPLREAVEVVRGEQTSDETVERVR 167
>UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Sphingomonas wittichii RW1
Length = 489
Score = 42.3 bits (95), Expect = 0.007
Identities = 35/160 (21%), Positives = 66/160 (41%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
+ +VG+G +G A++ A G+ V + D + + + L +L K G + A
Sbjct: 9 IAVVGAGTMGAGIALVAAQAGHAVRVIDTQDAALDRGRQSVARSLASLVKRGTI-DEAGA 67
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
+ + + D+A A A+ + E + E +++K +F+ L V I
Sbjct: 68 AAIAERIGWSTDVADAAPAALAI-EAIVERMDVKTGLFETLARHVAPGAILASNTSSLSI 126
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ + H NP + LVE++P+ T P V
Sbjct: 127 EAMASAVPGPERFAGLHFFNPVPAMKLVELIPSSRTAPTV 166
>UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 304
Score = 41.9 bits (94), Expect = 0.009
Identities = 39/163 (23%), Positives = 64/163 (39%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+V +VG G +GR A A+ GY VT++D+ + + I L +G ++
Sbjct: 8 QVLVVGGGTMGRQIAFQCAAHGYFVTIYDISAEVLQATQKRIGAYADYLVAEGHIQPQA- 66
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
A + + D A +A + E VPE+ LK +VF D TI
Sbjct: 67 AKRAINRISISTD-ARQAANADLLCEAVPEDPALKGEVFARFDRYCPQRTIFSTNASLLV 125
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
+ + + H P + L +++P T EV K
Sbjct: 126 PSQIAKATGRPDRFLALHFHQPVWVGNLADVMPHAGTSSEVVK 168
>UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 733
Score = 41.9 bits (94), Expect = 0.009
Identities = 39/168 (23%), Positives = 71/168 (42%), Gaps = 3/168 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+K+G++G+G++G A++ A G +V L D + DA K T G+ RG
Sbjct: 327 KKIGVLGAGMMGAGIALVSAQAGMEVVLID----RDQDAADKGKAYSATYMDKGIKRGKA 382
Query: 224 NADEQ---FQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
+++ + T DL A+K + E V E+ +K ++ + ++ ++ ++ I
Sbjct: 383 TPEKKEALLAQITATADLD-ALKGCDLIIEAVFEDPGVKAEMTKKVEAIIPEDCIFASNT 441
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
E Q I H +P + LVEI+ T K
Sbjct: 442 STLPITSLAEASVRPEQFIGIHFFSPVEKMFLVEIIKGEKTGDRAVAK 489
>UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius sp.
HTCC2601|Rep: Enoyl-CoA hydratase - Roseovarius sp.
HTCC2601
Length = 634
Score = 41.9 bits (94), Expect = 0.009
Identities = 40/161 (24%), Positives = 59/161 (36%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+ +VG+ G AM FA G V L D QI A A I G + G
Sbjct: 293 RAAVVGADSAGAGIAMCFARAGLPVVLIDTDAAQIERARARIAELWDQARDGGGIDGPTL 352
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
++ + T A A D + V E++ +++F LD + I
Sbjct: 353 VAQRARLELSTELHAAASADVVVA--AVSEDMTQTQEIFSALDRICKPGAILVNNGATLD 410
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ + VI H + P V L+E+V T PEV
Sbjct: 411 LDSIAQATRRPGDVIGMHFLQPDGAVRLLEVVRGARTAPEV 451
>UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2;
Sinorhizobium|Rep: 3-hydroxybutyryl-CoA epimerase -
Sinorhizobium medicae WSM419
Length = 442
Score = 41.9 bits (94), Expect = 0.009
Identities = 34/157 (21%), Positives = 65/157 (41%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
++G G +G A + G + + + E A+A ++ K + L A E
Sbjct: 49 VIGGGTMGTGIAAALCNAGLPLVIVERDEAAREGAVARLRAIFDGAVKRRRISAGLAA-E 107
Query: 236 QFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXXXX 415
+ V G D A+ + +A + E V E+L++K+ VF+ + + +
Sbjct: 108 RLARVTGATDYAV-LAEADLIIEAVFEDLDVKRDVFRKVAAACRHDAVLATNTSYLNPER 166
Query: 416 XXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+ + + + H +P + L+EIVP T PE
Sbjct: 167 IADGIASPERFLGLHFFSPAQVMKLLEIVPTGATAPE 203
>UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=9; Actinomycetales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Arthrobacter sp. (strain FB24)
Length = 290
Score = 41.9 bits (94), Expect = 0.009
Identities = 41/161 (25%), Positives = 64/161 (39%), Gaps = 1/161 (0%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK-VQLKTLEKDGLLRGNLN 226
VG++G G +G A F G V + + E A ++ K++E+ G GNL
Sbjct: 14 VGVLGGGRMGAGIAHAFLINGANVLVVERDEASAEAARERVESAAAKSIER-GATDGNL- 71
Query: 227 ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
DE + T D KD V E VPE+ ELK + ++ + D+
Sbjct: 72 -DEMVSRLSVTVDYD-DFKDRELVVEAVPEDWELKVASLREIEARLSDDAYLASNTSSLS 129
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+K + H NP L+E+V T P++
Sbjct: 130 VNGLARELKRPGNFLGLHFFNPVPASTLIEVVLGEQTSPDL 170
>UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative; n=1; Filobasidiella
neoformans|Rep: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 342
Score = 41.9 bits (94), Expect = 0.009
Identities = 41/173 (23%), Positives = 76/173 (43%), Gaps = 4/173 (2%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFD--VVEKQITDAIADIKVQLKTLEKDGLL 211
K E++ + G+GL+G A + A G +V L D + + + I+ ++ + +
Sbjct: 35 KVEELTVFGAGLMGAGIAQVGAQNGLKVELTDDPAILRNGINIISKSLARVAKKKSPDDI 94
Query: 212 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 391
G N + + T D + AV++A V E + E++++K+ +F LD + I
Sbjct: 95 EGFTN--NVLKNISTTTDSSQAVENADLVVEAIIESIKVKRDLFGFLDGKAKSDCIFATN 152
Query: 392 XXXXXXXXXXE--NMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
E + + +A+ H NP + LVEI+ P T E + R
Sbjct: 153 TSSLSVTEIAEACSPERQAKFAGLHFFNPVPAMKLVEIIRTPQTSQETYETLR 205
>UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 336
Score = 41.5 bits (93), Expect = 0.012
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 11/170 (6%)
Frame = +2
Query: 23 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 202
M++ + ++ ++G+G +G+ A++FA G VTL D + DA+ +T ++
Sbjct: 1 MSAAAEVTRIHVLGAGRMGQGIALVFAFAGIDVTLIDFKRR---DAVGQSAFDDRTRDEI 57
Query: 203 G------LLRGNLNADEQFQCVKGTCDLAI-----AVKDAIFVQECVPENLELKKKVFQN 349
+ G ++A + V +A AV+DA V E +PE L+ K +
Sbjct: 58 ARPLHAQVALGRIDAAQADAVVARIAIVARDGAAEAVRDADIVFEALPEVLDAKADALRW 117
Query: 350 LDNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEI 499
L VD ++ +++ +H +NP +PLVEI
Sbjct: 118 LGEHVDARATIASTTSTFVVTELQRHVVRPERMLNAHWLNPALLMPLVEI 167
>UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 304
Score = 41.5 bits (93), Expect = 0.012
Identities = 41/170 (24%), Positives = 71/170 (41%), Gaps = 3/170 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+KV I+G+G +G+ L A+ G++ ++D+ + A K +L+ L + R L
Sbjct: 10 KKVLILGAGSMGQQIGFLCAAKGFETAIYDLSPPLLDTA----KKRLEKLAGRFVSRHRL 65
Query: 224 NADEQFQC---VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
+E V T D A +A F+ E V E++E+K +VF+ + I
Sbjct: 66 TGEEAAAAMARVTLTPDSEQAAANADFISESVTESVEIKCRVFETFHPLCPARAIFTTNT 125
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ + H N +V+I+P P T PE + R
Sbjct: 126 SSLIPSMLTHAVGRPDRFAAFHFHN-TLTSDIVDIMPHPGTTPETAETIR 174
>UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein
NCU04393.1; n=2; Sordariales|Rep: Putative
uncharacterized protein NCU04393.1 - Neurospora crassa
Length = 420
Score = 41.5 bits (93), Expect = 0.012
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 17/175 (9%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVE-------KQITDAIADIKVQLKT---- 190
+ V I+G+G IGR A+++AS VT++D+ + + ITD +A ++ T
Sbjct: 93 QPVLIMGAGHIGRRVALVWASALRPVTVYDISKNALRSSTEYITDNLAKYCLEHGTHPGP 152
Query: 191 LEKDGLLRGNLNADEQ------FQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNL 352
+ LR A ++ F T + K V EC+PENL LK +
Sbjct: 153 VHFTSDLREATTAGKRHGLKLDFSAAHDTEPKSTRKKGPWMVIECLPENLSLKIAALAEI 212
Query: 353 DNVVDDNTIXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
+ ++ +N I +++H ++I +H PP V +VE++ + T
Sbjct: 213 ERLLPENCIIASNSSSLMTSEMAPHLQHPGRLINTHYYIPPRNV-MVEVMSSSHT 266
>UniRef50_Q0UJN7 Cluster: Predicted protein; n=1; Phaeosphaeria
nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
(Septoria nodorum)
Length = 152
Score = 41.5 bits (93), Expect = 0.012
Identities = 33/143 (23%), Positives = 55/143 (38%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ VGIVG+G+IG SW LF + G +V + D +K TL+ G +
Sbjct: 4 QTVGIVGTGVIGASWTGLFLAHGLRVLVADPAPGAKEKLEKHLKAIWPTLQSIGTKKSAS 63
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A+ F + ++ PE LK+ + +D+ V + +
Sbjct: 64 LANYTF----------VGASLGQHYKKNAPERQNLKQSLLAEIDSSVRSDVVIASSSSGI 113
Query: 404 XXXXXXENMKHKAQVIVSHPVNP 472
K +V++ HP NP
Sbjct: 114 PSSRFISKCKTPERVLIGHPFNP 136
>UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6;
Clostridium|Rep: Dihydrolipoyl dehydrogenase -
Clostridium oremlandii OhILAs
Length = 467
Score = 41.1 bits (92), Expect = 0.016
Identities = 27/96 (28%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +2
Query: 2 LQTLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ 181
+ T +++ K +++ I+G G+IG +A +F ++G +VT+F+ + DI +
Sbjct: 159 VMTSNELLSFKEIPKRLAIIGGGVIGIEFAGIFNALGSEVTVFEFAPSILIKLDKDISKR 218
Query: 182 LKT-LEKDGLLRGNLNADEQFQCVKGTCDLAIAVKD 286
L T L+KDG+ E+ + G+ L I KD
Sbjct: 219 LTTSLKKDGIKINTSTGVEEIKESNGS--LVIVAKD 252
>UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Paracoccus denitrificans PD1222|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 371
Score = 41.1 bits (92), Expect = 0.016
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 2/167 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG-LLRGNLN 226
+ ++G G +G A +A+ G+ V D V + A+ ++ L + G L + +L+
Sbjct: 4 IAVIGLGTMGLGIAQTYAAAGFAVLATDAVPEARETALGRLRAGLAPRVRAGKLAQADLD 63
Query: 227 AD-EQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A + V G A+ D E V E + +K+ +F L+ VV + +
Sbjct: 64 AILARITVVDGP--KAMGATDLAI--EAVVERMPVKQSLFAALEAVVAPDAVLASNTSSL 119
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
E + +++ H NP + LVE+V P T + R
Sbjct: 120 SMAAMAEGLARPERLLGLHFFNPAPVMKLVELVAHPGTGAAALDRAR 166
>UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=92;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bradyrhizobium japonicum
Length = 293
Score = 41.1 bits (92), Expect = 0.016
Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 2/155 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL--KTLEKDGLLRG 217
+KVG++G+G +G A + A G+ V L DV ++ +A I L + +K
Sbjct: 6 KKVGVIGAGQMGNGIAHVAALAGFDVVLNDVSADRLKSGMATINGNLARQVSKKVVTEEA 65
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
A + + DLA D V E E E+K+K+F L V+ I
Sbjct: 66 KTKALSRIVAAEKLDDLA----DCDLVIETAVEKEEVKRKIFHELCAVLKPEAIVASDTS 121
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ I H +NP VPL+E+V
Sbjct: 122 SISITRLAAATDRPERFIGIHFMNP---VPLMELV 153
>UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=95; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase (EC
4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase
(EC 1.1.1.35)] - Yersinia pseudotuberculosis
Length = 753
Score = 41.1 bits (92), Expect = 0.016
Identities = 40/166 (24%), Positives = 68/166 (40%), Gaps = 1/166 (0%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+VG++G GL+G A + A+ G V + D+ + I A+ L + +R
Sbjct: 317 RVGVLGGGLMGGGIANVTATRAGLPVRIKDINPQGINQALKYTWDALGKRVRSKRMRPT- 375
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
Q + G+ D + V E V E+L LK+++ +++ +TI
Sbjct: 376 EQQRQMMLISGSTDYR-GFERVDIVVEAVFEDLSLKQQMVADIERFGAAHTIFASNTSSL 434
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKT 541
+ QVI H +P +PLVE++P T E T
Sbjct: 435 PISQIAALAQRPEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIATT 480
>UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=116; cellular
organisms|Rep: Fatty acid oxidation complex subunit
alpha [Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Yersinia pestis
Length = 729
Score = 41.1 bits (92), Expect = 0.016
Identities = 35/153 (22%), Positives = 69/153 (45%), Gaps = 4/153 (2%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQI----TDAIADIKVQLKTLEKDGLLRGNL 223
++G+G++G A A V + D+ E + +A + QL+ + DGL ++
Sbjct: 318 VLGAGIMGGGIAYQSALKSVPVIMKDINENSLDLGMNEAAKLLNKQLERGKVDGLKMASI 377
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A ++ T D A ++ A + E V EN ++K V ++ ++ ++T+
Sbjct: 378 LAT-----IRPTLDYA-GIERAQVIVEAVVENPKVKAAVLAEVEALIGEDTVLASNTSTI 431
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+++K H NP + +PLVEI+
Sbjct: 432 PIDQLAKSLKRPENFCGMHFFNPVHRMPLVEII 464
>UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 953
Score = 40.7 bits (91), Expect = 0.021
Identities = 36/161 (22%), Positives = 63/161 (39%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+ ++G+G +G M G L + ++ + + ++ L K G +
Sbjct: 327 KSAAVIGAGTMGVGITMSMVMAGIPTYLTEQNQQYLDKGLKMVQGILAHWVKQGRM-SEA 385
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
A + F V+ T +KD V E V EN+ LKK++ + LD V + I
Sbjct: 386 KAQQIFSLVRPTLTYD-DLKDVDVVVEAVFENMALKKEILKTLDGVCKPSAILASNTSTL 444
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+V+ H +P + + L+E V T PE
Sbjct: 445 DIDEMASATTRPDKVMGMHFFSPAHIMKLLENVRGKDTSPE 485
>UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA
dehydrogenase,possibly related to diterpenoid
metabolism; n=6; Proteobacteria|Rep: DitN-like
3-hydroxyacyl-CoA dehydrogenase,possibly related to
diterpenoid metabolism - Azoarcus sp. (strain EbN1)
(Aromatoleum aromaticum (strain EbN1))
Length = 299
Score = 40.7 bits (91), Expect = 0.021
Identities = 33/153 (21%), Positives = 58/153 (37%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
EK+ +VG+GL+G A A GY++ L D + A+ I + K G L
Sbjct: 5 EKIIVVGAGLMGTGIAYSCAISGYRILLVDANPSALDKAVGQINSLVAAGVKLGKL-VEA 63
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
+ ++ +L DA + E E +++K + D ++ I
Sbjct: 64 AGKAALERLEAAIELDGRASDAALLIETATEKIDIKLAIIGKADELLPPEAIIASNTSAL 123
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ Q H NP + + LVE++
Sbjct: 124 SISELAAATRRPTQFAGMHFFNPVHKMKLVELI 156
>UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep:
3-hydroxybutyryl-coA dehydrogenase - Blastopirellula
marina DSM 3645
Length = 319
Score = 40.7 bits (91), Expect = 0.021
Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL-- 223
VG+VG GL+GR + +QV +D+ + A A + L+ L + + +
Sbjct: 6 VGVVGLGLMGRGICTSLLANNFQVVAYDINPESFAAARAHVASALEELARHPSVAEAIPE 65
Query: 224 NADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
N FQ T DL+ + D FV E +PE+ +K++ L+ ++ ++T
Sbjct: 66 NWPSHFQL---TADLS-PLGDCDFVIESIPEDPVIKQETIAALERLLPNSTPIASNTSAL 121
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ + ++I H P + +EI+
Sbjct: 122 PISLLQAHCQLPQRIIGMHWAEPCHLTRFLEII 154
>UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13;
cellular organisms|Rep: 3-hydroxybutyryl-CoA epimerase -
Pseudomonas putida W619
Length = 423
Score = 40.7 bits (91), Expect = 0.021
Identities = 36/171 (21%), Positives = 72/171 (42%), Gaps = 2/171 (1%)
Frame = +2
Query: 23 MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 202
+++ + ++ ++G+G +GR + A G V D + T+A + Q +
Sbjct: 12 VSTSYNVQQTAVIGAGTMGRGIVISLARAGLPVLWLD-NDPSATEAGLAMLAQTWAQQ-- 68
Query: 203 GLLRGNLNADEQFQCVKGTCDLA--IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNT 376
+ +G ++ + C+ + + +A V E V ENL LK+++F+ LD+ +
Sbjct: 69 -VGKGRIDQAQADACLARVRQVTAYTELAEADLVIEAVYENLALKQEIFRALDSTLKPEA 127
Query: 377 IXXXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
I QV+ H +P + + L+E+V T P V
Sbjct: 128 ILASNTSALDIDAIAAVTGRPEQVLGLHFFSPAHVMKLLEVVRGQLTAPAV 178
>UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Streptomyces avermitilis
Length = 272
Score = 40.3 bits (90), Expect = 0.028
Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 1/98 (1%)
Frame = +2
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDD-NTIXXXXXXXXX 406
+E V T DLA A +D V E PE+ K ++FQ LD V+D I
Sbjct: 53 EETLARVSFTTDLA-AFRDRQLVLEAAPEDEPTKLRIFQALDRAVEDPEAILATNTSALP 111
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTK 520
QV+ H NP +PLVE++ + T+
Sbjct: 112 VMRLARATDRPGQVLGLHFFNPAPVLPLVEVIGSLLTR 149
>UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation
complex; n=5; Betaproteobacteria|Rep: Alpha-subunit of
fatty acid oxidation complex - Azoarcus sp. (strain
EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 678
Score = 40.3 bits (90), Expect = 0.028
Identities = 42/158 (26%), Positives = 70/158 (44%), Gaps = 6/158 (3%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
+V +VG+G++G A + A G VTL D ++I A+ K E+ LRG+
Sbjct: 318 RVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGR---AAKLFERK--LRGD-T 371
Query: 227 ADEQFQCVKGTCDLAI------AVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXX 388
A + Q V+ D I + A V E + ENL+ K+ +F L+ + +
Sbjct: 372 ATKARQ-VRFALDRLIPDPHGHGARRADVVIEAIFENLDAKRALFAQLERRARPDAVLAT 430
Query: 389 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ + A+++ H NP +PLVE+V
Sbjct: 431 NTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVV 468
>UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Reinekea sp. MED297|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Reinekea sp. MED297
Length = 705
Score = 40.3 bits (90), Expect = 0.028
Identities = 39/154 (25%), Positives = 63/154 (40%), Gaps = 2/154 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 226
++G+VG+G++G A AS G V L D + + K + L RG L+
Sbjct: 315 RIGVVGAGMMGAGIAWACASKGLPVVLVDTEQSRAEQG----KGYSERLVAKRFERGRLS 370
Query: 227 ADEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXX 400
A+E + + + + V E V E+ LK V+Q + +VV TI
Sbjct: 371 AEEGTALLNRITPTESMSELAECDLVIEAVFEDRALKADVYQLIQSVVSPETIIASNTST 430
Query: 401 XXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ Q I H +P +PL+EI+
Sbjct: 431 LPISSLAGMVDRPDQFIGLHFFSPVDKMPLLEII 464
>UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Magnetococcus sp. MC-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Magnetococcus sp. (strain MC-1)
Length = 717
Score = 40.3 bits (90), Expect = 0.028
Identities = 37/156 (23%), Positives = 69/156 (44%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V +VG G++GR+ A+ A G QV+L + + + A+ + + D L +L
Sbjct: 312 VHVVGDGVMGRAIAVWCALQGMQVSLQGLSTELLGRALQEATQLARKKRLDRLATRDL-L 370
Query: 230 DEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
D +G V A V E + E++ K++++ L+ + ++ +
Sbjct: 371 DRLMPDQRGD-----GVCHADLVIEAIFEDVTAKQQLYAALEPRMREHALLATNTSAIPL 425
Query: 410 XXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWT 517
+ +K Q++ H NP +PLVE+V P T
Sbjct: 426 QTLAQGLKRPQQLLGLHFFNPVARMPLVEVVEGPQT 461
>UniRef50_A2QA05 Cluster: Catalytic activity:; n=4;
Trichocomaceae|Rep: Catalytic activity: - Aspergillus
niger
Length = 622
Score = 40.3 bits (90), Expect = 0.028
Identities = 30/115 (26%), Positives = 51/115 (44%)
Frame = +2
Query: 8 TLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK 187
T + KS + I+G+G++GR A +F+S GY V + D + A I +
Sbjct: 3 TTNTTITHPSKSRPIVIIGAGILGRRIAAVFSSAGYSVHISDPSPSALDSARTYISTHIH 62
Query: 188 TLEKDGLLRGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNL 352
+ R +L+ + + AV A + E VPE L +K+ +F +L
Sbjct: 63 EFTTH-IPRPSLSPGP----ISTFTSVPEAVATAWLIVEAVPEILPIKQSLFADL 112
>UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Acholeplasmataceae|Rep: Dihydrolipoyl dehydrogenase -
Acholeplasma laidlawii
Length = 336
Score = 40.3 bits (90), Expect = 0.028
Identities = 23/68 (33%), Positives = 41/68 (60%), Gaps = 1/68 (1%)
Frame = +2
Query: 8 TLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKV-QL 184
T R ++ K + + IVG G+IG +A +F S G +VT+ ++++ + DI+V
Sbjct: 162 TSRELLNVKNYPKSIVIVGGGVIGVEFATVFNSFGSKVTIIEMMDGILPTMDDDIRVAYA 221
Query: 185 KTLEKDGL 208
KTL++DG+
Sbjct: 222 KTLKRDGI 229
>UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n=1;
Geobacter metallireducens GS-15|Rep: 3-hydroxyacyl-CoA
dehydrogenase-like - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 290
Score = 39.9 bits (89), Expect = 0.038
Identities = 40/169 (23%), Positives = 71/169 (42%), Gaps = 5/169 (2%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
+KV I+G+G++G A+ A GY V L +V + I+ L + G L +
Sbjct: 5 KKVAILGAGMMGSDIALSCALAGYDVLLKEVSLDLAAAGVERIRGSLAKWSEKGRLA--V 62
Query: 224 NADEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI---XXX 388
+A++Q V D D V E + E+L++K + F+ L+ V + I
Sbjct: 63 DAEQQKSAVARITPVDNFSGFGDVDLVIEAIFEDLDVKSQNFRQLEEVCKPSCIIASNTS 122
Query: 389 XXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
+ + K++ + H +P + LVE+V T E +
Sbjct: 123 SLPITKLGACFSSAERKSRFVGMHFFSPAAIMKLVEVVNGEDTSAETVE 171
>UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1;
Acinetobacter sp. DF4|Rep:
3-hydroxyacyl-CoA-dehydrogenase - Acinetobacter sp. DF4
Length = 240
Score = 39.9 bits (89), Expect = 0.038
Identities = 34/119 (28%), Positives = 59/119 (49%), Gaps = 2/119 (1%)
Frame = +2
Query: 29 SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGL 208
+K+++ KVG++G+G++G A A G V L DV + +A K L+K +
Sbjct: 123 TKWQATKVGVLGAGMMGAGIAYSTAIKGIPVVLKDV---SVENAEKGKAYSQKLLDK-RV 178
Query: 209 LRGNLNADEQFQCVKGTCDLAIA--VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 379
+G + A+++ Q + A A ++ + E V EN ELK KV Q + + N +
Sbjct: 179 SQGRMTAEKRDQVLSLITATASAQDLQGCDLIIEAVFENQELKAKVTQEAEQYLAPNGV 237
>UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Ralstonia metallidurans
(strain CH34 / ATCC 43123 / DSM 2839)
Length = 714
Score = 39.9 bits (89), Expect = 0.038
Identities = 40/156 (25%), Positives = 66/156 (42%), Gaps = 3/156 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
++VGI+G+G++G A A G + L DV D K+ + L + G+ +G +
Sbjct: 316 KRVGILGAGMMGAGIAYASAMRGIEAVLKDV----SLDHAGKGKLHSEKLLEKGVSKGKI 371
Query: 224 N---ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
+ DE Q + T D A + + E V E ELK +V + + + +N +
Sbjct: 372 SPSKRDEVLQRITPTAD-ASGLAGCDIIIEAVYEKRELKAEVTREAEPHLAENGLFASNT 430
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
E I H +P +PLVEI+
Sbjct: 431 STLPITGLAEASASPENFIGLHFFSPVDRMPLVEII 466
>UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Geobacter sp. FRC-32|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Geobacter sp. FRC-32
Length = 311
Score = 39.9 bits (89), Expect = 0.038
Identities = 40/171 (23%), Positives = 65/171 (38%), Gaps = 5/171 (2%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEK-----DGLL 211
K I+G+G++GR W A G++V D + + +A + T K D
Sbjct: 2 KFAILGTGIMGRGWITQCAMSGHEVHCHDASPQTLAGTVAGCEKLAATAAKKFKHDDPNF 61
Query: 212 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXX 391
N + KG A K E + E+L+LK V + + + +
Sbjct: 62 VSNAMGKIRVHNEKGA--FIDAAKGCDVFLEVIFEDLKLKCSVLADYLPQLPPSVVFWSN 119
Query: 392 XXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKKTR 544
+ + IV+H +NP +P VE+VP T E + TR
Sbjct: 120 SSSLDIDPMAQAGGRPDRSIVTHGMNPVPLMPGVEVVPGAKTSSETIEFTR 170
>UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Vibrio cholerae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Vibrio cholerae
Length = 284
Score = 39.9 bits (89), Expect = 0.038
Identities = 37/168 (22%), Positives = 68/168 (40%), Gaps = 4/168 (2%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFASVGYQVTLFDVV--EKQITDAIADIKVQLKTLEKDGLLRGN 220
KV +VG+G++G+ + + +V + +IA + + + K +
Sbjct: 2 KVAVVGNGVMGKGIVEILLCYTKLAGIESIVWISRDTESSIASTSLLSRKVVKFLKTKSE 61
Query: 221 LN--ADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXX 394
++ E ++ T D + A+K A V E V E+ ++K + + VVDD TI
Sbjct: 62 IDFPPSESMAALQITSDFS-ALKSAELVIEAVSEDKDVKHDIMAKIAAVVDDTTIVASNT 120
Query: 395 XXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
N + + H NP + LVE+V T + +K
Sbjct: 121 SSLSITELAANFRKPENFLGLHFFNPAPMMSLVEVVRGLTTCESIIEK 168
>UniRef50_A3T2M8 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=4; cellular organisms|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Sulfitobacter sp. NAS-14.1
Length = 695
Score = 39.9 bits (89), Expect = 0.038
Identities = 41/160 (25%), Positives = 67/160 (41%), Gaps = 6/160 (3%)
Frame = +2
Query: 41 SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 220
+E +VG G +G + A A+ G VT VVE+ + A K L+ L G+ RG
Sbjct: 286 AETAIVVGGGNMGAAIAYTLATAGISVT---VVERSASSAEWASK-NLQKLIDQGISRGI 341
Query: 221 LNADEQFQCVKGTCDLAIAVK--DAI----FVQECVPENLELKKKVFQNLDNVVDDNTIX 382
L+ D K D + V DA+ E E+ +K + L+ + TI
Sbjct: 342 LSVD----AAKTVEDRLVTVSGYDALPPTDLAIEAAFEDFAVKTAILTELEGALPPETII 397
Query: 383 XXXXXXXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+ +KH A+ + H +P + + L+E+V
Sbjct: 398 ATNTSYLDVNRLSDGLKHPARFVGMHFFSPAHIMKLLEVV 437
>UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family; n=1; Salinibacter ruber DSM
13855|Rep: 3-hydroxyacyl-CoA dehydrogenase, C-terminal
domain family - Salinibacter ruber (strain DSM 13855)
Length = 802
Score = 39.5 bits (88), Expect = 0.050
Identities = 38/165 (23%), Positives = 70/165 (42%), Gaps = 4/165 (2%)
Frame = +2
Query: 56 IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 235
++G+G +G A A+ G +V L D+ D A ++ + + ADE
Sbjct: 27 VLGAGTMGAQIAAHLANAGLEVHLLDIAPDD-DDPNAVVREGFEQAREAS--PDPFFADE 83
Query: 236 QFQCVK-GTCDLAIAVKDAI-FVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXXX 409
V G + A+ ++ E V E +++K+ V ++ D+ +
Sbjct: 84 AADRVHLGNFEEHFDRIGAVDWIVEAVVERMDVKRDVHARIEAHAADDAVISTNTSGLPI 143
Query: 410 XXXXENMK--HKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTKK 538
E K + + +H NPP Y+ L+E+VP T P+VT++
Sbjct: 144 HAITEGRSADFKRRFLGTHFYNPPRYLKLLELVPTDATDPDVTER 188
>UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=36; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 740
Score = 39.5 bits (88), Expect = 0.050
Identities = 37/155 (23%), Positives = 62/155 (40%)
Frame = +2
Query: 38 KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 217
K KVG++G+G +G A + A G V L D ++ A + L K G
Sbjct: 326 KIRKVGVLGAGFMGAGIAYVTAKAGIPVVLIDRDQESADKGKAHSAGLMDGLIKKGRATA 385
Query: 218 NLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
++ + T D + A++ A V E V E+ +KK+ + + + + I
Sbjct: 386 E-EKEKLLSLITATPDYS-ALEGADLVIEAVFEDSAVKKEATEKAEAALKSSAIFASNTS 443
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+N K I H +P + LVEI+
Sbjct: 444 TIPITSLAKNSKRPKNFIGLHFFSPVDRMMLVEII 478
>UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Deltaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 795
Score = 39.5 bits (88), Expect = 0.050
Identities = 41/181 (22%), Positives = 87/181 (48%), Gaps = 16/181 (8%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITD-------AIAD--IKVQLKTLE 196
++V ++G+G++G + A A+ G++V L DVV K+ ++ + D ++ ++
Sbjct: 5 DRVAVLGAGVMGSTIAAHLANAGFRVLLLDVVPKEPSEEERAAGLGLGDRAVRDRIAAAG 64
Query: 197 KDGLLR---GNLNADEQFQCVK-GTC-DLAIAVKDAIFVQECVPENLELKKKVFQNLDNV 361
+ GL R L E ++ G D ++D +V E V E+L +K+++ +
Sbjct: 65 RAGLERLKPAPLYLPEHAGRIEVGNLEDDLPRLRDRDWVIEVVVEDLAVKQQLLGRVAAH 124
Query: 362 VDDNTIXXXXXXXXXXXXXXENMKH--KAQVIVSHPVNPPYYVPLVEIVPAPWTKPEVTK 535
+ + + E++ + +++V+H NPP Y+ LVE+V + +T V
Sbjct: 125 LRPDAVLSTNTSGLSVNALAESLPEPLRPRLLVTHFFNPPRYMRLVELVSSRFTDRAVAA 184
Query: 536 K 538
+
Sbjct: 185 R 185
>UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;
n=3; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Nitrococcus mobilis Nb-231
Length = 726
Score = 39.5 bits (88), Expect = 0.050
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 3/164 (1%)
Frame = +2
Query: 47 KVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 220
+VG++G+GL+G + + A+ V L DV K + + I ++ + L + + R
Sbjct: 331 RVGVLGAGLMGAGISFVTAARAKVPVRLKDVEPKGLASGLKYIDERIDQRLSRHAISRFE 390
Query: 221 LNADEQFQC-VKGTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
E+ +C V T D + + V E V E+LELK ++ + ++ + + I
Sbjct: 391 A---ERARCRVTPTLDFS-GCRSLDLVIEAVFEDLELKHRMIREVEANCNADVIFASNTS 446
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+ + VI H +P +PL+E++ T PEV
Sbjct: 447 SLPLARIAQAAERPQNVIGLHYFSPVDRMPLLEVIAHERTAPEV 490
>UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65;
cellular organisms|Rep: Dihydrolipoyl dehydrogenase -
Pseudomonas fluorescens
Length = 478
Score = 39.5 bits (88), Expect = 0.050
Identities = 20/56 (35%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDGL 208
+K+G++G+G+IG ++A +G +VT+ + ++K + A I K LK L K GL
Sbjct: 182 KKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGL 237
>UniRef50_Q8CXB6 Cluster: UDP-glucose:GDP-mannose dehydrogenase;
n=2; Bacillaceae|Rep: UDP-glucose:GDP-mannose
dehydrogenase - Oceanobacillus iheyensis
Length = 440
Score = 39.1 bits (87), Expect = 0.066
Identities = 16/40 (40%), Positives = 26/40 (65%)
Frame = +2
Query: 35 FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQIT 154
+ + KVG++G G +G A+LF GYQVT D+ + +I+
Sbjct: 12 YVNSKVGVIGMGYVGLPLALLFLKKGYQVTGIDINQSKIS 51
>UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Symbiobacterium thermophilum|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Symbiobacterium
thermophilum
Length = 190
Score = 39.1 bits (87), Expect = 0.066
Identities = 36/164 (21%), Positives = 65/164 (39%), Gaps = 2/164 (1%)
Frame = +2
Query: 44 EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 223
E++ ++G + G A L A GY L + + + +A ++ +L + +G G
Sbjct: 2 ERITVIGGTVAGVEIAALMARAGYATCLHEPDQAALAEAGRRLQDRLLGRQGEG---GGA 58
Query: 224 NADEQFQCVKGTCDLA--IAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXX 397
+ Q V+ + +AV DA V E +L K+++F LD+ + I
Sbjct: 59 ASVAQLAAVRVRLEAVPEVAVADADLVIEASSVDLPGKRELFARLDSFAPAHAILATCSP 118
Query: 398 XXXXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPEV 529
+V+ +PP P V ++ P PEV
Sbjct: 119 TISSAYLAAATSRPDRVVSLGFFSPPLAPPAVAVIQEPHLAPEV 162
>UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Xanthomonadaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 693
Score = 38.7 bits (86), Expect = 0.087
Identities = 41/152 (26%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
V ++G G++G A A G+ VTL D ++ I A+ KD R + A
Sbjct: 320 VHVIGVGVMGGDIAAWAAYKGFDVTLQDREQRFIDTALTRGGELFAKRVKDDAKRPAVAA 379
Query: 230 DEQFQCVKGTCDLAIA-VKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXXX 406
++G DLA A V A V E + EN + K+ ++Q+++ + + +
Sbjct: 380 R-----LRG--DLAGAGVTQADLVIEAIIENPQAKRDLYQSIEPQLKPDALLTTNTSSIP 432
Query: 407 XXXXXENMKHKAQVIVSHPVNPPYYVPLVEIV 502
+++ AQ H NP +PLVEIV
Sbjct: 433 LTDLRGHIQRPAQFAGLHYFNPVAMMPLVEIV 464
>UniRef50_A6LMV1 Cluster: Putative uncharacterized protein
precursor; n=1; Thermosipho melanesiensis BI429|Rep:
Putative uncharacterized protein precursor - Thermosipho
melanesiensis BI429
Length = 208
Score = 38.7 bits (86), Expect = 0.087
Identities = 22/51 (43%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +2
Query: 32 KFKSEK-VGIVGSGLIGRSWAMLFASVGYQVTL-FDVVEKQITDAIADIKV 178
K KS+K +GI G+GL+GR+ A L + G+ V + FD EK+I D I +
Sbjct: 109 KLKSKKNIGIYGAGLVGRALAQLLLNRGFNVVVFFDDDEKKIGDRYLGIPI 159
>UniRef50_A5ZCW2 Cluster: Putative uncharacterized protein; n=1;
Bacteroides caccae ATCC 43185|Rep: Putative
uncharacterized protein - Bacteroides caccae ATCC 43185
Length = 448
Score = 38.7 bits (86), Expect = 0.087
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Frame = +2
Query: 35 FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK-VQLKTLEKDGLL 211
FK K+ + G+G +G S A L S + VT DV+ +++ I +Q +EK L
Sbjct: 4 FKDIKIAVAGTGYVGLSIATLL-SQHHHVTTVDVIPEKVEKLNNKISPIQDDYIEKY-LA 61
Query: 212 RGNLNADEQFQCVKGTCDLAIAVKDAIFVQECVPENLELKKKVF--QNLDNVVD 367
+LN + T D A A KDA +V P N + +K F ++++V+D
Sbjct: 62 EKDLN-------LTATLDGAAAYKDADYVVIAAPTNYDPQKNFFDTHHIEDVID 108
>UniRef50_A3VIL7 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacterales bacterium HTCC2654
Length = 695
Score = 38.7 bits (86), Expect = 0.087
Identities = 40/161 (24%), Positives = 63/161 (39%), Gaps = 2/161 (1%)
Frame = +2
Query: 50 VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 229
VG+VG+G + R AM G VT V + AI ++ +++ D + G L+
Sbjct: 302 VGVVGAGALARDVAMAALKAGVPVT----VALEDDTAITRVRGRIERAFGDAVEAGTLSG 357
Query: 230 DEQFQCVK--GTCDLAIAVKDAIFVQECVPENLELKKKVFQNLDNVVDDNTIXXXXXXXX 403
E+ ++ T D A+ D + E + E+ K + L V +TI
Sbjct: 358 RERDDRLRRLNTADDYGALDDKDVIIEALAEDSVRKTQALGQLSQVAAGHTIFASSTAEC 417
Query: 404 XXXXXXENMKHKAQVIVSHPVNPPYYVPLVEIVPAPWTKPE 526
+ H + P LVEI PA T+PE
Sbjct: 418 DIETLAGASGRPDRFAAMHFIAPADANRLVEIAPARGTRPE 458
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 530,576,272
Number of Sequences: 1657284
Number of extensions: 10187495
Number of successful extensions: 35572
Number of sequences better than 10.0: 444
Number of HSP's better than 10.0 without gapping: 34158
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 35374
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 35405708495
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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