Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0003_C07
(475 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P34896 Cluster: Serine hydroxymethyltransferase, cytoso... 254 6e-67
UniRef50_Q5BJF5 Cluster: Serine hydroxymethyltransferase; n=3; E... 235 4e-61
UniRef50_P34897 Cluster: Serine hydroxymethyltransferase, mitoch... 235 4e-61
UniRef50_A4SBB9 Cluster: Serine hydroxymethyltransferase; n=11; ... 220 1e-56
UniRef50_Q9LM59 Cluster: Serine hydroxymethyltransferase; n=21; ... 198 4e-50
UniRef50_UPI0000E49DF3 Cluster: PREDICTED: similar to serine hyd... 196 3e-49
UniRef50_Q23KJ4 Cluster: Serine hydroxymethyltransferase family ... 191 6e-48
UniRef50_O62585 Cluster: Serine hydroxymethyltransferase, cytoso... 180 2e-44
UniRef50_A2EAE3 Cluster: Serine hydroxymethyltransferase; n=1; T... 173 1e-42
UniRef50_Q7RQX7 Cluster: Serine hydroxymethyltransferase; n=4; P... 158 5e-38
UniRef50_A0CF19 Cluster: Chromosome undetermined scaffold_174, w... 148 5e-35
UniRef50_Q8KC36 Cluster: Serine hydroxymethyltransferase; n=103;... 147 9e-35
UniRef50_Q9U638 Cluster: SHMT; n=5; Aconoidasida|Rep: SHMT - Pla... 145 4e-34
UniRef50_Q5CM80 Cluster: Serine hydroxymethyltransferase; n=2; C... 145 5e-34
UniRef50_Q9A8J6 Cluster: Serine hydroxymethyltransferase; n=42; ... 144 7e-34
UniRef50_Q8FQR1 Cluster: Serine hydroxymethyltransferase; n=37; ... 144 1e-33
UniRef50_Q6G3L3 Cluster: Serine hydroxymethyltransferase; n=163;... 143 2e-33
UniRef50_Q8EWD1 Cluster: Serine hydroxymethyltransferase; n=14; ... 140 2e-32
UniRef50_Q98A81 Cluster: Serine hydroxymethyltransferase 2; n=4;... 140 2e-32
UniRef50_Q6LHN7 Cluster: Serine hydroxymethyltransferase 2; n=27... 140 2e-32
UniRef50_A6PKY7 Cluster: Serine hydroxymethyltransferase; n=2; B... 138 6e-32
UniRef50_Q11NZ7 Cluster: Serine hydroxymethyltransferase; n=6; B... 136 2e-31
UniRef50_Q62I16 Cluster: Serine hydroxymethyltransferase 1; n=45... 130 1e-29
UniRef50_Q72IH2 Cluster: Serine hydroxymethyltransferase; n=6; B... 130 2e-29
UniRef50_Q12RK5 Cluster: Glycine hydroxymethyltransferase; n=2; ... 130 2e-29
UniRef50_Q89HS7 Cluster: Serine hydroxymethyltransferase; n=2; R... 128 8e-29
UniRef50_Q9RYB2 Cluster: Serine hydroxymethyltransferase; n=43; ... 127 1e-28
UniRef50_Q183S3 Cluster: Serine hydroxymethyltransferase; n=1; C... 122 4e-27
UniRef50_Q057P9 Cluster: Serine hydroxymethyltransferase; n=3; G... 122 4e-27
UniRef50_Q9PJW0 Cluster: Serine hydroxymethyltransferase; n=8; C... 121 7e-27
UniRef50_A7D249 Cluster: Glycine hydroxymethyltransferase; n=1; ... 118 9e-26
UniRef50_Q9HPY5 Cluster: Serine hydroxymethyltransferase; n=79; ... 107 9e-23
UniRef50_O83349 Cluster: Serine hydroxymethyltransferase; n=18; ... 104 9e-22
UniRef50_Q883D8 Cluster: Serine hydroxymethyltransferase, putati... 100 1e-20
UniRef50_Q05FV9 Cluster: Serine hydroxymethyltransferase; n=1; C... 93 3e-18
UniRef50_Q5CM83 Cluster: Serine hydroxymethyltransferase 2; n=2;... 79 5e-14
UniRef50_UPI00006DBC17 Cluster: hypothetical protein BdolA_01004... 76 5e-13
UniRef50_O29406 Cluster: Serine hydroxymethyltransferase; n=6; E... 74 1e-12
UniRef50_Q97AK0 Cluster: Serine hydroxymethyltransferase; n=3; T... 72 6e-12
UniRef50_A5K3J5 Cluster: Serine hydroxymethyltransferase, putati... 71 1e-11
UniRef50_A6TST7 Cluster: Glycine hydroxymethyltransferase; n=1; ... 70 3e-11
UniRef50_Q9YAH7 Cluster: Serine hydroxymethyltransferase; n=9; A... 70 3e-11
UniRef50_Q8TZ19 Cluster: Serine hydroxymethyltransferase; n=8; E... 69 5e-11
UniRef50_Q9HI38 Cluster: Serine hydroxymethyltransferase; n=5; T... 66 3e-10
UniRef50_Q6L0Q9 Cluster: Serine hydroxymethyltransferase; n=1; P... 65 7e-10
UniRef50_Q8ZYF9 Cluster: Serine hydroxymethyltransferase; n=5; T... 64 2e-09
UniRef50_Q8IKR8 Cluster: Putative uncharacterized protein; n=1; ... 62 6e-09
UniRef50_A0RYP2 Cluster: Glycine/serine hydroxymethyltransferase... 61 1e-08
UniRef50_UPI000038E502 Cluster: hypothetical protein Faci_030016... 60 2e-08
UniRef50_Q0FXL6 Cluster: Serine hydroxymethyltransferase; n=1; F... 58 7e-08
UniRef50_Q0S5S0 Cluster: Glycine hydroxymethyltransferase; n=1; ... 58 1e-07
UniRef50_Q0GPG8 Cluster: BZIP transcription factor bZIP94; n=1; ... 58 1e-07
UniRef50_Q9TSA5 Cluster: Serine hydroxymethyltransferase; n=1; O... 56 3e-07
UniRef50_A0GN01 Cluster: Glycine hydroxymethyltransferase; n=1; ... 55 9e-07
UniRef50_Q7RRP9 Cluster: Serine hydroxymethyltransferase, mitoch... 54 2e-06
UniRef50_Q5C0V4 Cluster: SJCHGC07535 protein; n=1; Schistosoma j... 54 2e-06
UniRef50_Q28QL6 Cluster: Glycine hydroxymethyltransferase; n=7; ... 52 6e-06
UniRef50_UPI0000DAE560 Cluster: hypothetical protein Rgryl_01000... 42 0.007
UniRef50_O33942 Cluster: EryCIV; n=11; Actinomycetales|Rep: EryC... 39 0.065
UniRef50_Q0AVP5 Cluster: Selenocysteine lyase; n=2; Clostridiale... 38 0.15
UniRef50_Q3A5G7 Cluster: Pyridoxal-phosphate-dependent aminotran... 37 0.26
UniRef50_Q8GGQ5 Cluster: Serine hydroxymethyltransferase; n=1; S... 37 0.26
UniRef50_Q5KZ59 Cluster: Aminotransferase; n=10; Bacteria|Rep: A... 36 0.46
UniRef50_A6RBG5 Cluster: Predicted protein; n=1; Ajellomyces cap... 36 0.46
UniRef50_Q2RVH6 Cluster: Aminotransferase, class V; n=3; Bacteri... 36 0.60
UniRef50_A0Y9H9 Cluster: DegT/DnrJ/EryC1/StrS aminotransferase; ... 35 0.80
UniRef50_Q0UBV4 Cluster: Predicted protein; n=1; Phaeosphaeria n... 35 0.80
UniRef50_Q9KVA5 Cluster: Perosamine synthase; n=7; Vibrio choler... 34 1.4
UniRef50_Q8YZC3 Cluster: DegT/DnrJ/EryC1/StrS family; n=7; Bacte... 34 1.8
UniRef50_A4E729 Cluster: Putative uncharacterized protein; n=4; ... 33 2.4
UniRef50_Q8TXP1 Cluster: UPF0425 pyridoxal phosphate-dependent p... 33 2.4
UniRef50_A0C8P8 Cluster: Chromosome undetermined scaffold_159, w... 33 3.2
UniRef50_Q5ACU5 Cluster: Putative uncharacterized protein PIB1; ... 33 4.3
UniRef50_UPI0000384B0D Cluster: COG0399: Predicted pyridoxal pho... 32 5.6
UniRef50_Q85302 Cluster: Homologue of retroviral pseudoprotease;... 32 5.6
UniRef50_O67617 Cluster: Transcriptional regulator; n=2; Aquifex... 32 5.6
UniRef50_A7DGE7 Cluster: DegT/DnrJ/EryC1/StrS aminotransferase; ... 32 5.6
UniRef50_A4AP52 Cluster: Perosamine synthetase; n=1; Flavobacter... 32 5.6
UniRef50_O10368 Cluster: Early 53 kDa protein; n=8; Nucleopolyhe... 32 5.6
UniRef50_A5FNU5 Cluster: TonB-dependent receptor; n=1; Flavobact... 32 7.4
UniRef50_Q6K9D9 Cluster: Putative uncharacterized protein OJ1471... 32 7.4
UniRef50_UPI0000584CE3 Cluster: PREDICTED: hypothetical protein;... 31 9.8
UniRef50_A6X7T2 Cluster: Diguanylate cyclase precursor; n=1; Och... 31 9.8
UniRef50_A0LTD4 Cluster: Major facilitator superfamily MFS_1; n=... 31 9.8
UniRef50_Q5BGG2 Cluster: Putative uncharacterized protein; n=1; ... 31 9.8
UniRef50_Q8PWQ9 Cluster: Cysteine desulfurase; n=5; Euryarchaeot... 31 9.8
>UniRef50_P34896 Cluster: Serine hydroxymethyltransferase,
cytosolic; n=86; root|Rep: Serine
hydroxymethyltransferase, cytosolic - Homo sapiens
(Human)
Length = 483
Score = 254 bits (623), Expect = 6e-67
Identities = 117/159 (73%), Positives = 138/159 (86%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
KISATSIFFESMPYKV+P TG I+YD+L E A+LF P++IIAG SCYSR L+Y R R+IA
Sbjct: 159 KISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIA 218
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-K 358
DENGAYLMADMAH+SGLVAAGV+PSPFEHC +VTTTTHKTLRG RAG+IF+RKGV+SV
Sbjct: 219 DENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDP 278
Query: 359 ANGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
G++++Y+ E IN AVFPGLQGGPHNHAIA +A A+K
Sbjct: 279 KTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALK 317
>UniRef50_Q5BJF5 Cluster: Serine hydroxymethyltransferase; n=3;
Euarchontoglires|Rep: Serine hydroxymethyltransferase -
Homo sapiens (Human)
Length = 480
Score = 235 bits (575), Expect = 4e-61
Identities = 109/159 (68%), Positives = 136/159 (85%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R +DY R R++
Sbjct: 158 RISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVC 217
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-K 358
DE A+L+ADMAH+SGLVAA VIPSPF+H DIVTTTTHKTLRG R+G+IF+RKGV++V
Sbjct: 218 DEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDP 277
Query: 359 ANGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
G+++ Y FE +IN AVFP LQGGPHNHAIAA+A A+K
Sbjct: 278 KTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALK 316
>UniRef50_P34897 Cluster: Serine hydroxymethyltransferase,
mitochondrial precursor; n=160; Eukaryota|Rep: Serine
hydroxymethyltransferase, mitochondrial precursor - Homo
sapiens (Human)
Length = 504
Score = 235 bits (575), Expect = 4e-61
Identities = 109/159 (68%), Positives = 136/159 (85%), Gaps = 1/159 (0%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
+ISATSIFFESMPYK++P TGLIDY++LA TA+LF+PR+IIAG S Y+R +DY R R++
Sbjct: 182 RISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVC 241
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSV-K 358
DE A+L+ADMAH+SGLVAA VIPSPF+H DIVTTTTHKTLRG R+G+IF+RKGV++V
Sbjct: 242 DEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDP 301
Query: 359 ANGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
G+++ Y FE +IN AVFP LQGGPHNHAIAA+A A+K
Sbjct: 302 KTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALK 340
>UniRef50_A4SBB9 Cluster: Serine hydroxymethyltransferase; n=11;
Viridiplantae|Rep: Serine hydroxymethyltransferase -
Ostreococcus lucimarinus CCE9901
Length = 525
Score = 220 bits (537), Expect = 1e-56
Identities = 98/158 (62%), Positives = 124/158 (78%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
KISATSIFF S+PY++D +TGLIDYD +TA L +P++I+AG S Y+R DY R R+IA
Sbjct: 196 KISATSIFFTSVPYRLDESTGLIDYDACEKTAALVRPKLIVAGASAYARLYDYPRMRKIA 255
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
D + A L+ADMAH+SGLVAAG +PSPF++ D+VTTTTHK+LRGPR +IF+RKG +
Sbjct: 256 DNSNAILLADMAHISGLVAAGEVPSPFDYADVVTTTTHKSLRGPRGAMIFYRKGEKGKDK 315
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
G +MYD E KI+ AVFPGLQGGPHNH IA +A A+K
Sbjct: 316 KGNPIMYDLESKIDFAVFPGLQGGPHNHTIAGLAVALK 353
>UniRef50_Q9LM59 Cluster: Serine hydroxymethyltransferase; n=21;
Eukaryota|Rep: Serine hydroxymethyltransferase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 599
Score = 198 bits (484), Expect = 4e-50
Identities = 95/164 (57%), Positives = 122/164 (74%), Gaps = 6/164 (3%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K+S SIFFES PYKVDP TG IDYDKL E A ++P+++I G S Y R ++ RFR IA
Sbjct: 276 KVSGASIFFESFPYKVDPRTGYIDYDKLEEKALDYRPKILICGGSSYPRDWEFPRFRHIA 335
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVR---- 349
D+ GA LM DMA +SGLVAA P+PF++CDIVT+TTHK+LRGPR G+IF+++G++
Sbjct: 336 DKCGAVLMFDMAQISGLVAAKESPNPFDYCDIVTSTTHKSLRGPRGGIIFYKRGLKPKKQ 395
Query: 350 SVKAN--GQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
S+ N + YDFE KIN +VFP LQGGPHN+ IAA+A A+K
Sbjct: 396 SINLNHCESNIQYDFEEKINFSVFPSLQGGPHNNHIAALAIALK 439
>UniRef50_UPI0000E49DF3 Cluster: PREDICTED: similar to serine
hydroxymethyltransferase isoform 1; n=4; Coelomata|Rep:
PREDICTED: similar to serine hydroxymethyltransferase
isoform 1 - Strongylocentrotus purpuratus
Length = 496
Score = 196 bits (477), Expect = 3e-49
Identities = 88/115 (76%), Positives = 106/115 (92%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
KISATS+FFESMPY+V+P TGLIDY+ LA A+LF+P++IIAGMSCY R LDYKRF++IA
Sbjct: 211 KISATSLFFESMPYRVNPKTGLIDYEALAVNARLFRPQMIIAGMSCYPRNLDYKRFKEIA 270
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGV 346
EN AYL+ADMAHVSGLVAAGV+ +PFE+CDIVT+TTHKTLRGPR+G+IFFR+GV
Sbjct: 271 VENDAYLLADMAHVSGLVAAGVVANPFEYCDIVTSTTHKTLRGPRSGIIFFRRGV 325
>UniRef50_Q23KJ4 Cluster: Serine hydroxymethyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep: Serine
hydroxymethyltransferase family protein - Tetrahymena
thermophila SB210
Length = 515
Score = 191 bits (466), Expect = 6e-48
Identities = 83/158 (52%), Positives = 114/158 (72%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K+SA S++FE + Y ++ +GLIDYDKL E +K F P+VI G YSR +DY+R R+I
Sbjct: 194 KLSAGSVYFEILNYGINEKSGLIDYDKLEEQSKYFLPKVIFGGADLYSRKIDYERLRKIC 253
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
D GA L+ D+ VSGLVA ++P PF++ DIVT+ THK+LRGPR ++F+++GV+ V
Sbjct: 254 DSIGATLVVDLGQVSGLVATKILPDPFKYADIVTSATHKSLRGPRGALVFYKQGVKGVDK 313
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
G ++ YDF+ KI A+FPG QGGPHNH IA IA A+K
Sbjct: 314 KGNEIKYDFKNKIENAIFPGSQGGPHNHTIAGIAVALK 351
>UniRef50_O62585 Cluster: Serine hydroxymethyltransferase,
cytosolic; n=1; Encephalitozoon cuniculi|Rep: Serine
hydroxymethyltransferase, cytosolic - Encephalitozoon
cuniculi
Length = 460
Score = 180 bits (437), Expect = 2e-44
Identities = 89/157 (56%), Positives = 115/157 (73%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
KISA+S++F+S PY V + GLIDY+ L +T F P ++I G S YSR +DYKR + IA
Sbjct: 147 KISASSVYFDSRPYTVG-SNGLIDYEGLEKTFTDFLPHILICGYSAYSRDIDYKRLQSIA 205
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
NGA+L AD++H+S LVA+G++ SPFEHCDIV TTT K LRGPR +IF+R R+V
Sbjct: 206 GRNGAFLFADISHISPLVASGLMNSPFEHCDIVMTTTQKGLRGPRGALIFYR---RAVTK 262
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAM 472
NG+ V D + +IN AVFP LQGGPHNH IA IA+A+
Sbjct: 263 NGETV--DLDARINFAVFPMLQGGPHNHTIAGIASAL 297
>UniRef50_A2EAE3 Cluster: Serine hydroxymethyltransferase; n=1;
Trichomonas vaginalis G3|Rep: Serine
hydroxymethyltransferase - Trichomonas vaginalis G3
Length = 451
Score = 173 bits (422), Expect = 1e-42
Identities = 83/158 (52%), Positives = 113/158 (71%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K+S++SIF+ S Y ++P T LID++KL + AK P++I+AG S Y R +D+K FR+I
Sbjct: 153 KVSSSSIFWNSEQYTLNPKTSLIDFEKLEQKAKELHPKLIVAGASAYPRFIDFKEFRKIC 212
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
++ + LM+D+AH SGL+AAG+ PSPFE+ DIVTTTTHKTLRGPR ++FF+K
Sbjct: 213 NQTNSILMSDVAHYSGLIAAGLYPSPFEYSDIVTTTTHKTLRGPRGALVFFKK------- 265
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
++E KIN A+FP LQGGPH H IAAIA A+K
Sbjct: 266 -------EYEKKINSAIFPTLQGGPHLHQIAAIAVALK 296
>UniRef50_Q7RQX7 Cluster: Serine hydroxymethyltransferase; n=4;
Plasmodium|Rep: Serine hydroxymethyltransferase -
Plasmodium yoelii yoelii
Length = 446
Score = 158 bits (384), Expect = 5e-38
Identities = 84/158 (53%), Positives = 104/158 (65%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K+S TS FES YK + + G +D D + E A FKP VII G S Y R LDYKRFR+IA
Sbjct: 144 KVSVTSDMFESKLYKSN-SEGYVDLDVVREMALSFKPNVIICGYSSYPRDLDYKRFREIA 202
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
DE AYL+AD+AH+S +A G + +PF + D+VTTTTHK LRGPR+ +IFF K K
Sbjct: 203 DEVNAYLLADIAHISSFIACGNLNNPFLYADVVTTTTHKILRGPRSAMIFFNK-----KR 257
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
N E KIN +VFP QGGPHN+ IAA+A +K
Sbjct: 258 NP-----GIEQKINSSVFPSFQGGPHNNKIAAVACQLK 290
>UniRef50_A0CF19 Cluster: Chromosome undetermined scaffold_174,
whole genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_174,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 439
Score = 148 bits (359), Expect = 5e-35
Identities = 74/158 (46%), Positives = 105/158 (66%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K+SA S FE + Y+++ T IDYDK+ AK +KP++I+AG S YS+ +D+ RFR I
Sbjct: 145 KLSAISKIFEVLFYQLNEKTQEIDYDKVEILAKAYKPKLIVAGCSAYSKLIDFGRFRNIC 204
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
D+ GA L+AD+AH SGL++AGVIPSPF + DIV TTTHK+LRGPR +I+++
Sbjct: 205 DQVGAILLADIAHTSGLMSAGVIPSPFPYADIVMTTTHKSLRGPRGSLIYYK-------- 256
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
++ +I+++V PGL G H H I IA A+K
Sbjct: 257 ------LQYKNRIDESVAPGLVAGAHFHTITGIAVALK 288
>UniRef50_Q8KC36 Cluster: Serine hydroxymethyltransferase; n=103;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Chlorobium tepidum
Length = 440
Score = 147 bits (357), Expect = 9e-35
Identities = 78/162 (48%), Positives = 103/162 (63%), Gaps = 6/162 (3%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K++ + FF++ Y VD TG+ID +K+ E A+ KP++II G S YS+ D+K FR++A
Sbjct: 130 KVNFSGQFFDAHSYGVDKETGIIDMNKVEEMARRVKPKLIITGASAYSQGFDFKAFREVA 189
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRK------G 343
D+ GA LMAD+AH +GLVAAG+ +P HC VTTTTHKTLRGPR G+I K G
Sbjct: 190 DKVGALLMADIAHPAGLVAAGLSANPMPHCHFVTTTTHKTLRGPRGGMIMMGKDFENPLG 249
Query: 344 VRSVKANGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATA 469
+ NG +V E I+ V PG+QGGP H IA A A
Sbjct: 250 LTINTKNGSRVKMMSE-VIDAEVMPGIQGGPLMHIIAGKAVA 290
>UniRef50_Q9U638 Cluster: SHMT; n=5; Aconoidasida|Rep: SHMT -
Plasmodium falciparum
Length = 442
Score = 145 bits (352), Expect = 4e-34
Identities = 75/158 (47%), Positives = 101/158 (63%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K+S TS FES YK + + G +D + + A F+P+VII G + Y R +DYK FR+I
Sbjct: 140 KVSITSDLFESKLYKCN-SEGYVDMESVRNLALSFQPKVIICGYTSYPRDIDYKGFREIC 198
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
DE AYL AD++H+S VA ++ +PF + D+VTTTTHK LRGPR+ +IFF K K
Sbjct: 199 DEVNAYLFADISHISSFVACNLLNNPFTYADVVTTTTHKILRGPRSALIFFNK-----KR 253
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
N + KIN +VFP QGGPHN+ IAA+A +K
Sbjct: 254 NP-----GIDQKINSSVFPSFQGGPHNNKIAAVACQLK 286
>UniRef50_Q5CM80 Cluster: Serine hydroxymethyltransferase; n=2;
Cryptosporidium|Rep: Serine hydroxymethyltransferase -
Cryptosporidium hominis
Length = 445
Score = 145 bits (351), Expect = 5e-34
Identities = 75/158 (47%), Positives = 106/158 (67%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
+++ +S +FES+PY D G+IDYDKL E A LF+P++IIAG S Y R +++KRFR I
Sbjct: 138 RVNCSSHYFESLPYVTD-LEGVIDYDKLEENAILFRPKMIIAGASGYPRMINFKRFRDIC 196
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
D+ AYLM D+AH SGLV AG PSP ++ D +TTT+HKTLRGPR+ +IF+RK V S
Sbjct: 197 DKVKAYLMVDIAHYSGLVVAGKYPSPKDYADFITTTSHKTLRGPRSAIIFYRKEVES--- 253
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
K+ KI+++V +Q H + +AA+ +K
Sbjct: 254 ---KIRV----KIDESVSKEIQSSIHFNQVAALCFQLK 284
>UniRef50_Q9A8J6 Cluster: Serine hydroxymethyltransferase; n=42;
Bacteria|Rep: Serine hydroxymethyltransferase -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 429
Score = 144 bits (350), Expect = 7e-34
Identities = 76/149 (51%), Positives = 96/149 (64%)
Frame = +2
Query: 23 FFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYL 202
+F+ + Y V LIDYD +AE A+ KP++IIAG S YSR +D+ +FR+IAD GAYL
Sbjct: 146 WFKPISYSVRQQDQLIDYDGVAEVAQREKPKLIIAGGSAYSREIDFAKFREIADSIGAYL 205
Query: 203 MADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMY 382
M DMAH +GL+A G +P H IVTTTTHKTLRGPR G++ N + ++
Sbjct: 206 MVDMAHYAGLIAGGAYANPIPHAHIVTTTTHKTLRGPRGGLVL---------TNDEAII- 255
Query: 383 DFEGKINQAVFPGLQGGPHNHAIAAIATA 469
K+N AVFPGLQGGP H IAA A A
Sbjct: 256 ---KKVNSAVFPGLQGGPLEHVIAAKAVA 281
>UniRef50_Q8FQR1 Cluster: Serine hydroxymethyltransferase; n=37;
Bacteria|Rep: Serine hydroxymethyltransferase -
Corynebacterium efficiens
Length = 434
Score = 144 bits (348), Expect = 1e-33
Identities = 77/158 (48%), Positives = 102/158 (64%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K++ + +E Y VDP T L+D D++ E A +P+VIIAG S Y R LD+ FR+IA
Sbjct: 139 KLNFSGKLYEVAAYGVDPDTMLVDMDQVREQAIKEQPKVIIAGWSAYPRHLDFAAFREIA 198
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
DE GA L DMAH +GLVAAG+ PSP + D+V++T HKTL GPR+G+I ++
Sbjct: 199 DEVGATLWVDMAHFAGLVAAGLHPSPVPYADVVSSTVHKTLGGPRSGIILAKQ------- 251
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
D+ K+N +VFPG QGGP HAIAA ATA+K
Sbjct: 252 -------DYAKKLNSSVFPGQQGGPLMHAIAAKATALK 282
>UniRef50_Q6G3L3 Cluster: Serine hydroxymethyltransferase; n=163;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Bartonella henselae (Rochalimaea henselae)
Length = 437
Score = 143 bits (347), Expect = 2e-33
Identities = 76/157 (48%), Positives = 99/157 (63%)
Frame = +2
Query: 5 ISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIAD 184
++ + +F+S+ Y V L+D + + AK KP++IIAG S YSR D+K+FR+IAD
Sbjct: 142 VNMSGKWFKSISYGVRKEDQLLDMEAVERLAKEHKPKLIIAGGSAYSRLWDWKKFREIAD 201
Query: 185 ENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKAN 364
E GAYL+ DM+H++GLVA GV PSP H IVTTTTHK+LRGPR G+I +
Sbjct: 202 EIGAYLLVDMSHIAGLVAGGVHPSPVPHAHIVTTTTHKSLRGPRGGLILTNDEI------ 255
Query: 365 GQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
KIN A+FPGLQGGP H IAA A A +
Sbjct: 256 -------LAKKINSAIFPGLQGGPLMHVIAAKAVAFE 285
>UniRef50_Q8EWD1 Cluster: Serine hydroxymethyltransferase; n=14;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Mycoplasma penetrans
Length = 412
Score = 140 bits (338), Expect = 2e-32
Identities = 72/152 (47%), Positives = 100/152 (65%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K++ + +E+ Y VD T +DYD + + A+ KP++I+ G S YSR +D+K+F +IA
Sbjct: 123 KVNISGKTYEADHYGVDKETQCLDYDAILKQAQEVKPKLIVCGASNYSRVVDFKKFGEIA 182
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
GAYL+AD+AH+SGL+ AG P+P + DIVTTTTHKTLRGPR+G+I
Sbjct: 183 KSVGAYLLADVAHISGLIVAGYHPNPLPYADIVTTTTHKTLRGPRSGLIL---------T 233
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAA 457
N ++++ KIN AVFPG QGGP H IAA
Sbjct: 234 NNEELI----KKINSAVFPGSQGGPLMHVIAA 261
>UniRef50_Q98A81 Cluster: Serine hydroxymethyltransferase 2; n=4;
Bacteria|Rep: Serine hydroxymethyltransferase 2 -
Rhizobium loti (Mesorhizobium loti)
Length = 437
Score = 140 bits (338), Expect = 2e-32
Identities = 65/150 (43%), Positives = 97/150 (64%)
Frame = +2
Query: 26 FESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLM 205
++ +PY + T IDYD+L ETA+ +P++I G + Y R DY +IA E +YL+
Sbjct: 144 YQRVPYGLHDKTQQIDYDRLRETARRERPKLIWVGGTSYPRVFDYAAMAEIALEANSYLV 203
Query: 206 ADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYD 385
AD+AH+SGL+ AG P+P HCD+VT+T+HK++RGPR G I + R ++
Sbjct: 204 ADIAHISGLIVAGAHPNPVVHCDVVTSTSHKSIRGPRGGFILSKNEDRYQALYHSTSKHN 263
Query: 386 FEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
+I++AVFP LQGGPH + IAA+A A++
Sbjct: 264 LAKRIDRAVFPQLQGGPHMNTIAALAVALQ 293
>UniRef50_Q6LHN7 Cluster: Serine hydroxymethyltransferase 2; n=27;
Bacteria|Rep: Serine hydroxymethyltransferase 2 -
Photobacterium profundum (Photobacterium sp. (strain
SS9))
Length = 431
Score = 140 bits (338), Expect = 2e-32
Identities = 73/149 (48%), Positives = 96/149 (64%)
Frame = +2
Query: 23 FFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYL 202
+F+++ Y V+ T IDY+++ E A KP++IIAG S R +++ +FR+IADE GA+L
Sbjct: 149 WFDAVQYGVNKDTLEIDYNQVRELAIEHKPKMIIAGGSAIPRIINFAKFREIADEVGAFL 208
Query: 203 MADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMY 382
M DMAH++GL+AAG PSP H ++TTTTHKTLRGPR G+I +
Sbjct: 209 MVDMAHIAGLIAAGEHPSPIPHAHVITTTTHKTLRGPRGGMILTN-------------LE 255
Query: 383 DFEGKINQAVFPGLQGGPHNHAIAAIATA 469
D KIN AVFPGLQGGP H IA A A
Sbjct: 256 DINKKINSAVFPGLQGGPLMHVIAGKAVA 284
>UniRef50_A6PKY7 Cluster: Serine hydroxymethyltransferase; n=2;
Bacteria|Rep: Serine hydroxymethyltransferase -
Victivallis vadensis ATCC BAA-548
Length = 572
Score = 138 bits (334), Expect = 6e-32
Identities = 72/153 (47%), Positives = 96/153 (62%)
Frame = +2
Query: 5 ISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIAD 184
++ + + + +PY V+ T +IDYD++ A KPR+IIAG S Y R +D+ R R IAD
Sbjct: 289 LNFSGMLYNIVPYGVNRETEMIDYDEVERLAVENKPRMIIAGASAYPRVIDFARLRAIAD 348
Query: 185 ENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKAN 364
GA L DMAH++GLVAAG P+P +CD+VTTTTHKTLRGPR G+I ++
Sbjct: 349 LVGAKLFVDMAHIAGLVAAGEHPNPVPYCDVVTTTTHKTLRGPRGGLILCKE-------- 400
Query: 365 GQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIA 463
++ IN VFPG+QGGP H IAA A
Sbjct: 401 ------EYLKSINSKVFPGMQGGPLEHVIAAKA 427
>UniRef50_Q11NZ7 Cluster: Serine hydroxymethyltransferase; n=6;
Bacteria|Rep: Serine hydroxymethyltransferase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 431
Score = 136 bits (329), Expect = 2e-31
Identities = 73/161 (45%), Positives = 100/161 (62%), Gaps = 4/161 (2%)
Frame = +2
Query: 5 ISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIAD 184
++ + +F++ Y V+ +GLI+ D + TA KP++II G S YSR DY RFR+IAD
Sbjct: 133 VNMSGKYFKAHFYGVEKESGLINMDIVEATALKVKPKMIICGASAYSRDWDYARFRKIAD 192
Query: 185 ENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRS---V 355
GA L+AD++H +GL+A G++ P HC IV+TTTHKTLRGPR GVI K + +
Sbjct: 193 SVGAILLADISHPAGLIAKGLLNDPIPHCHIVSTTTHKTLRGPRGGVIMMGKDFENPFGL 252
Query: 356 KA-NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
K G+ M ++ VFPG QGGP H IAA A A +
Sbjct: 253 KTPKGETRM--MSNVLDMGVFPGTQGGPLEHVIAAKAVAFQ 291
>UniRef50_Q62I16 Cluster: Serine hydroxymethyltransferase 1; n=454;
root|Rep: Serine hydroxymethyltransferase 1 -
Burkholderia mallei (Pseudomonas mallei)
Length = 415
Score = 130 bits (315), Expect = 1e-29
Identities = 66/136 (48%), Positives = 87/136 (63%)
Frame = +2
Query: 68 IDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVAAGV 247
IDY+ + A KP++I+AG S ++ +D++R +IA GAYLM DMAH +GL+AAGV
Sbjct: 154 IDYEAAEQLAHEHKPKLIVAGASAFALKIDFERLAKIAKAVGAYLMVDMAHYAGLIAAGV 213
Query: 248 IPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDFEGKINQAVFPGLQ 427
P+P H D VTTTTHK+LRGPR GVI + ++E +IN A+FPG+Q
Sbjct: 214 YPNPVPHADFVTTTTHKSLRGPRGGVILMKA--------------EYEKQINSAIFPGIQ 259
Query: 428 GGPHNHAIAAIATAMK 475
GGP H IAA A A K
Sbjct: 260 GGPLMHVIAAKAVAFK 275
>UniRef50_Q72IH2 Cluster: Serine hydroxymethyltransferase; n=6;
Bacteria|Rep: Serine hydroxymethyltransferase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 407
Score = 130 bits (314), Expect = 2e-29
Identities = 68/156 (43%), Positives = 98/156 (62%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
+++ + ++ + Y V P T LID +++ A +P+VI+AG S Y R D+K FR+IA
Sbjct: 128 RVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPRFWDFKAFREIA 187
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
DE GAYL+ DMAH +GLVAAG+ P+P + +VT+TTHKTLRGPR G+I +
Sbjct: 188 DEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLIL---------S 238
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATA 469
N + +I++ +FPG+QGGP H IA A A
Sbjct: 239 NDP----ELGKRIDKLIFPGIQGGPLEHVIAGKAVA 270
>UniRef50_Q12RK5 Cluster: Glycine hydroxymethyltransferase; n=2;
Gammaproteobacteria|Rep: Glycine
hydroxymethyltransferase - Shewanella denitrificans
(strain OS217 / ATCC BAA-1090 / DSM 15013)
Length = 451
Score = 130 bits (313), Expect = 2e-29
Identities = 65/155 (41%), Positives = 97/155 (62%)
Frame = +2
Query: 5 ISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIAD 184
++ + +++++ Y + GLIDYD++ + A+L KPR+II G + YSR +D++RFR+IAD
Sbjct: 147 VTFSGSYYQAIGYGTT-SQGLIDYDEVLKLARLHKPRLIICGATAYSRIVDFERFREIAD 205
Query: 185 ENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKAN 364
E GA L+AD++H++GLVA G PSP + TT THK L GPR G+I + +
Sbjct: 206 EVGAILLADISHIAGLVATGRHPSPINAAHVTTTCTHKQLAGPRGGLIMSGRDANEMVPG 265
Query: 365 GQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATA 469
K F + Q+VFP +QG P + IAA A A
Sbjct: 266 RNKT---FAASLEQSVFPWMQGAPAVNIIAAKAAA 297
>UniRef50_Q89HS7 Cluster: Serine hydroxymethyltransferase; n=2;
Rhizobiales|Rep: Serine hydroxymethyltransferase -
Bradyrhizobium japonicum
Length = 460
Score = 128 bits (308), Expect = 8e-29
Identities = 69/159 (43%), Positives = 97/159 (61%), Gaps = 2/159 (1%)
Frame = +2
Query: 5 ISATSIFFESMPYKVDPTTG-LIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
+S F + YK P+ G ID+D+L A+ +P++++ G S Y R LDY F+ IA
Sbjct: 164 VSHMGRLFNFIRYKTAPSNGGAIDFDELRAIAREARPKMVLCGYSSYPRDLDYAAFKSIA 223
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEH-CDIVTTTTHKTLRGPRAGVIFFRKGVRSVK 358
DE GA MAD++H GLVAA V+ +P + D++TTT+HKTLRGPR G+I RK
Sbjct: 224 DEVGALTMADVSHYGGLVAANVMRNPLDAGFDVMTTTSHKTLRGPRGGIILCRK------ 277
Query: 359 ANGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
+ G+I+ +VFPGLQGGPH + +A IA +K
Sbjct: 278 --------ENAGRIDASVFPGLQGGPHMNVVAGIAVTLK 308
>UniRef50_Q9RYB2 Cluster: Serine hydroxymethyltransferase; n=43;
Bacteria|Rep: Serine hydroxymethyltransferase -
Deinococcus radiodurans
Length = 408
Score = 127 bits (307), Expect = 1e-28
Identities = 67/156 (42%), Positives = 97/156 (62%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K + + + ++ + Y++D T ID +++ A KP++IIAG S YSR +D+ FR+IA
Sbjct: 132 KANFSGMRYQMVAYQLDRETERIDMEEVRRLAHEHKPKMIIAGASAYSRVIDFAAFREIA 191
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
DE GA L AD+AH++GL+AAG P+ H +V +TTHKTLRGPR G+I A
Sbjct: 192 DEVGALLFADIAHIAGLIAAGEHPNALPHAHVVASTTHKTLRGPRGGIIL---------A 242
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATA 469
N ++ ++++ VFPG QGGP H IAA A A
Sbjct: 243 NDPEI----AKQLDRTVFPGYQGGPLEHVIAAKAVA 274
>UniRef50_Q183S3 Cluster: Serine hydroxymethyltransferase; n=1;
Clostridium difficile 630|Rep: Serine
hydroxymethyltransferase - Clostridium difficile (strain
630)
Length = 418
Score = 122 bits (294), Expect = 4e-27
Identities = 67/144 (46%), Positives = 89/144 (61%)
Frame = +2
Query: 41 YKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAH 220
Y VDP TG IDYD L AK +P++IIAG S Y R +DY+R ++A E GAY M DMAH
Sbjct: 142 YGVDPNTGRIDYDALEAKAKECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAH 201
Query: 221 VSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDFEGKI 400
V+GLVAA VIPSP + D V+++T KT GPR+G++ KA K K+
Sbjct: 202 VAGLVAAKVIPSPVPYADFVSSSTTKTFCGPRSGIVL-------CKAEHAK-------KL 247
Query: 401 NQAVFPGLQGGPHNHAIAAIATAM 472
++ VFPG G H + +AA A ++
Sbjct: 248 DKGVFPGTLGSIHLNTVAAKAFSL 271
>UniRef50_Q057P9 Cluster: Serine hydroxymethyltransferase; n=3;
Gammaproteobacteria|Rep: Serine hydroxymethyltransferase
- Buchnera aphidicola subsp. Cinara cedri
Length = 417
Score = 122 bits (294), Expect = 4e-27
Identities = 65/150 (43%), Positives = 91/150 (60%)
Frame = +2
Query: 26 FESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLM 205
++S Y V+ G IDYD L + L +P++II G S YS D+K R+IADE AY
Sbjct: 138 YKSFSYGVNKC-GEIDYDALKYLSHLHRPKMIIGGFSAYSGICDWKYMRKIADEINAYFF 196
Query: 206 ADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYD 385
D++H+ GL+ AG+ P+P ++ +V+TTTHKTL GPR G+I + G K +Y
Sbjct: 197 VDISHIVGLIVAGIYPNPLKYAHVVSTTTHKTLGGPRGGLI--------ISNCGNKKIY- 247
Query: 386 FEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
K++ +VFPG QGGP H IAA A + K
Sbjct: 248 --SKLDSSVFPGSQGGPLMHVIAAKAISFK 275
>UniRef50_Q9PJW0 Cluster: Serine hydroxymethyltransferase; n=8;
Chlamydiaceae|Rep: Serine hydroxymethyltransferase -
Chlamydia muridarum
Length = 497
Score = 121 bits (292), Expect = 7e-27
Identities = 70/161 (43%), Positives = 96/161 (59%), Gaps = 3/161 (1%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
+I+ S +PY+V+ T L DYD +A+ AK +P V+IAG S YSR L++ +QIA
Sbjct: 188 RINVMSKLMHCLPYEVNLDTELFDYDVIAKIAKEHRPTVLIAGYSSYSRRLNFATLKQIA 247
Query: 182 DENGAYLMADMAHVSGLVAAGVI---PSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRS 352
++ GA L DMAH +GLVA GV +P + DIVTTTTHKTLRGPR G++ +K
Sbjct: 248 EDCGAVLWVDMAHFAGLVAGGVFIGEENPIPYADIVTTTTHKTLRGPRGGLVLAKK---- 303
Query: 353 VKANGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
++ +N+A P + GGP H IAA A A+K
Sbjct: 304 ----------EYSDTLNKAC-PLMMGGPLPHVIAAKAVALK 333
>UniRef50_A7D249 Cluster: Glycine hydroxymethyltransferase; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: Glycine
hydroxymethyltransferase - Halorubrum lacusprofundi ATCC
49239
Length = 460
Score = 118 bits (283), Expect = 9e-26
Identities = 64/154 (41%), Positives = 89/154 (57%)
Frame = +2
Query: 14 TSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENG 193
T +E Y+VD TG IDY+ L E A+ F+P ++++G S Y R +D++ + AD
Sbjct: 179 TGQIYEVEQYEVDADTGYIDYEGLREAAEEFEPDIVVSGYSAYPRTVDWEEIQAAADAVD 238
Query: 194 AYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQK 373
AY +AD+AH++GLVAAGV PSP D VT +THKT+R R G++ +
Sbjct: 239 AYHLADIAHITGLVAAGVHPSPVGVADFVTGSTHKTIRAGRGGIVMCDE----------- 287
Query: 374 VMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
+F I++AVFPG QGGP H IA A K
Sbjct: 288 ---EFADDIDKAVFPGGQGGPLMHNIAGKAVGFK 318
>UniRef50_Q9HPY5 Cluster: Serine hydroxymethyltransferase; n=79;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Halobacterium salinarium (Halobacterium halobium)
Length = 415
Score = 107 bits (258), Expect = 9e-23
Identities = 61/146 (41%), Positives = 83/146 (56%)
Frame = +2
Query: 26 FESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLM 205
+E Y+VD TG +DY+ L E A F+P +I++G S Y R ++++R + AD GA M
Sbjct: 138 YEVEQYEVDAETGRLDYEALREHADAFEPDMIVSGFSAYPREVEWERIQAAADAVGALHM 197
Query: 206 ADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYD 385
AD+AH++GLVAAG SP D VT +THKT+R R G++ +
Sbjct: 198 ADIAHITGLVAAGEHASPVGVADFVTGSTHKTIRAGRGGIVMCDEA-------------- 243
Query: 386 FEGKINQAVFPGLQGGPHNHAIAAIA 463
F I+ AVFPG QGGP H IA A
Sbjct: 244 FADDIDSAVFPGAQGGPLMHNIAGKA 269
>UniRef50_O83349 Cluster: Serine hydroxymethyltransferase; n=18;
Bacteria|Rep: Serine hydroxymethyltransferase -
Treponema pallidum
Length = 574
Score = 104 bits (250), Expect = 9e-22
Identities = 53/108 (49%), Positives = 69/108 (63%), Gaps = 3/108 (2%)
Frame = +2
Query: 26 FESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLM 205
F + Y VD TGL+DY + AK +P +++AG S Y R ++++ FR+IAD+ GA LM
Sbjct: 195 FRVVSYAVDRDTGLLDYAAIEAQAKRERPLILLAGYSAYPRSINFRIFREIADKVGAVLM 254
Query: 206 ADMAHVSGLVAAGVI---PSPFEHCDIVTTTTHKTLRGPRAGVIFFRK 340
ADMAH +GLVA GV P IVT+TTHKTLRGPR I +K
Sbjct: 255 ADMAHFAGLVAGGVFTGDEDPVRWSHIVTSTTHKTLRGPRGAFILCKK 302
>UniRef50_Q883D8 Cluster: Serine hydroxymethyltransferase, putative;
n=1; Pseudomonas syringae pv. tomato|Rep: Serine
hydroxymethyltransferase, putative - Pseudomonas
syringae pv. tomato
Length = 364
Score = 100 bits (240), Expect = 1e-20
Identities = 46/109 (42%), Positives = 67/109 (61%)
Frame = +2
Query: 2 KISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIA 181
K++ + +FF Y VD T LIDYD + A FKP++I+ G S Y R D +R R+I+
Sbjct: 74 KVNFSGMFFNFRHYGVDEATDLIDYDLAEQDAIRFKPKLIVCGSSSYPRLFDARRLREIS 133
Query: 182 DENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVI 328
D+ GA LM D++H +GL+A G IP+P D+ T + KT+RG +I
Sbjct: 134 DKVGALLMFDLSHEAGLIACGAIPNPVPLADVATMSMDKTMRGAHGAII 182
>UniRef50_Q05FV9 Cluster: Serine hydroxymethyltransferase; n=1;
Candidatus Carsonella ruddii PV|Rep: Serine
hydroxymethyltransferase - Carsonella ruddii (strain PV)
Length = 398
Score = 93.1 bits (221), Expect = 3e-18
Identities = 49/137 (35%), Positives = 82/137 (59%)
Frame = +2
Query: 23 FFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYL 202
+F+ + Y +D I+ + L + K KP+++I G S Y + +D+ F ++ +N ++
Sbjct: 130 YFDIVNYLLDKNFS-INKEYLYKIIKKEKPKILILGYSSYQKYIDWDFFYYLSIKNNCFV 188
Query: 203 MADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMY 382
++D++H+SGL+A+G+ PSP + +VTTTTHKTLRG + G+I K++
Sbjct: 189 ISDISHISGLIASGLYPSPLNYSSLVTTTTHKTLRGIKGGIIL---------TQNSKII- 238
Query: 383 DFEGKINQAVFPGLQGG 433
KIN +VFPG QGG
Sbjct: 239 ---KKINLSVFPGQQGG 252
>UniRef50_Q5CM83 Cluster: Serine hydroxymethyltransferase 2; n=2;
Cryptosporidium|Rep: Serine hydroxymethyltransferase 2 -
Cryptosporidium hominis
Length = 438
Score = 79.0 bits (186), Expect = 5e-14
Identities = 45/155 (29%), Positives = 79/155 (50%), Gaps = 4/155 (2%)
Frame = +2
Query: 23 FFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYL 202
+++ Y +D D L E K+ KP++++ + +DY+ +I E +L
Sbjct: 133 YYQVEYYNLDKKGRGFDIADLREKCKILKPKLLLVPSDVLTLFIDYRLLSEICSEFKIFL 192
Query: 203 MADMAHVSGLVAAGVIP----SPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQ 370
+AD++ ++ L++ +P+ +CDI+ + T +L GP+ G + N
Sbjct: 193 VADISEIALLISFDRYGKEKNNPYRYCDIIYSNTQSSLGGPKGGFLML---------NNS 243
Query: 371 KVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
K F+ K+N AVFPGLQGGPHNH I + A ++
Sbjct: 244 KNPGLFQ-KVNSAVFPGLQGGPHNHQIGSFAVQIQ 277
>UniRef50_UPI00006DBC17 Cluster: hypothetical protein
BdolA_01004192; n=1; Burkholderia dolosa AUO158|Rep:
hypothetical protein BdolA_01004192 - Burkholderia
dolosa AUO158
Length = 122
Score = 75.8 bits (178), Expect = 5e-13
Identities = 55/121 (45%), Positives = 61/121 (50%)
Frame = -2
Query: 468 AVAIAAMAWL*GPP*SPGNTAWLIFPSKSYITFCPFALTERTPLRKNMTPARGPRSVLCV 289
A A+ A+ + GPP PGNTA LIF FA++ K P RGPRSVLCV
Sbjct: 14 ATALPAITCISGPPCRPGNTAELIF----------FAISSSLVSTK---PPRGPRSVLCV 60
Query: 288 VVVTMSQCSKGLGITPAATRPDTCAMSAIK*APFSSAICLNRL*SRHRE*QLIPAIITRG 109
V VT CS G PAA P CAMS I AP SAI R S R PA+I G
Sbjct: 61 VDVTTCACSTGFAWRPAAITPAMCAMSTISFAPTLSAIARKRAKSSARGYAEKPAMIRLG 120
Query: 108 L 106
L
Sbjct: 121 L 121
>UniRef50_O29406 Cluster: Serine hydroxymethyltransferase; n=6;
Euryarchaeota|Rep: Serine hydroxymethyltransferase -
Archaeoglobus fulgidus
Length = 438
Score = 74.1 bits (174), Expect = 1e-12
Identities = 45/135 (33%), Positives = 69/135 (51%), Gaps = 1/135 (0%)
Frame = +2
Query: 68 IDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVAAGV 247
+D D+ + A+ +P++ I G S K R+IADE GAY+M D +HV GL+A
Sbjct: 162 VDVDETRKVAERERPKLFILGSSLILFRQPVKEIREIADEIGAYVMYDASHVLGLIAGKA 221
Query: 248 IPSPF-EHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDFEGKINQAVFPGL 424
+P E D++T +THKT GP+ +I RK + K+++AVFPG+
Sbjct: 222 FQNPLKEGADVMTGSTHKTFFGPQRAIIASRK--------------ELAEKVDRAVFPGV 267
Query: 425 QGGPHNHAIAAIATA 469
H + +A A
Sbjct: 268 VSNHHLNTLAGYVVA 282
>UniRef50_Q97AK0 Cluster: Serine hydroxymethyltransferase; n=3;
Thermoplasma|Rep: Serine hydroxymethyltransferase -
Thermoplasma volcanium
Length = 389
Score = 72.1 bits (169), Expect = 6e-12
Identities = 30/87 (34%), Positives = 50/87 (57%)
Frame = +2
Query: 68 IDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVAAGV 247
ID++ +T +P+V+I G S + + D + R++ + G+ L+ D +HV GL+A G
Sbjct: 144 IDFESFEKTIDYIRPKVVILGQSVFVKSYDIPKVRELCNSVGSMLLYDASHVMGLIAGGT 203
Query: 248 IPSPFEHCDIVTTTTHKTLRGPRAGVI 328
CD+V +THKT GP+ G+I
Sbjct: 204 FQKDIGLCDVVFGSTHKTFFGPQGGII 230
>UniRef50_A5K3J5 Cluster: Serine hydroxymethyltransferase, putative;
n=1; Plasmodium vivax|Rep: Serine
hydroxymethyltransferase, putative - Plasmodium vivax
Length = 470
Score = 70.9 bits (166), Expect = 1e-11
Identities = 31/117 (26%), Positives = 61/117 (52%)
Frame = +2
Query: 68 IDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVAAGV 247
+DYD++ + F P ++ + +Y F + D N ++A++++ L++
Sbjct: 182 VDYDEIHKIYDAFNPHLVHVDETNNPHNFNYDFFSSLKDINKCVVVANISNKGSLISQDF 241
Query: 248 IPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDFEGKINQAVFP 418
IPSPF H D+V T ++ +R VIF+++G + V G+ + Y++E K+ P
Sbjct: 242 IPSPFNHSDVVYTYFNENMRAHNCHVIFYKRGYKQVDKEGKLIHYEYEKKLKNQFLP 298
>UniRef50_A6TST7 Cluster: Glycine hydroxymethyltransferase; n=1;
Alkaliphilus metalliredigens QYMF|Rep: Glycine
hydroxymethyltransferase - Alkaliphilus metalliredigens
QYMF
Length = 368
Score = 69.7 bits (163), Expect = 3e-11
Identities = 35/89 (39%), Positives = 54/89 (60%), Gaps = 1/89 (1%)
Frame = +2
Query: 65 LIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVAAG 244
++D +KL + A KP++II G S K R+IAD+ G L D +HV+GL+A+G
Sbjct: 111 VVDAEKLKKQALALKPKMIIFGGSGTLFFEPIKELREIADQEGIILAYDASHVTGLIASG 170
Query: 245 VIPSPFEH-CDIVTTTTHKTLRGPRAGVI 328
+ P+P E DI+ +THK+ GP+ G +
Sbjct: 171 MFPNPLEEGADIMFGSTHKSFPGPQGGFV 199
>UniRef50_Q9YAH7 Cluster: Serine hydroxymethyltransferase; n=9;
Archaea|Rep: Serine hydroxymethyltransferase - Aeropyrum
pernix
Length = 439
Score = 69.7 bits (163), Expect = 3e-11
Identities = 50/154 (32%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
Frame = +2
Query: 5 ISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIAD 184
+ A I SMPY D +D DK + + KPR + G S Y + +
Sbjct: 137 LGALGIEQVSMPY--DEENMNVDVDKAVKLIEEVKPRFAVLGGSVYIFPHPTREIAEAIH 194
Query: 185 ENGAYLMADMAHVSGLVAAGVIPSPFEH-CDIVTTTTHKTLRGPRAGVIFFRKGVRSVKA 361
G L+ D AHV GL+ G P+P E D VT +THKT GP+ G +FFR
Sbjct: 195 SVGGKLIYDAAHVLGLIMGGAWPNPLERGADAVTGSTHKTFPGPQGGAVFFR-------- 246
Query: 362 NGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIA 463
+ +Y K+++ +FP H H I A A
Sbjct: 247 --DEQLYK---KVSKTIFPWWVSNHHLHRIPATA 275
>UniRef50_Q8TZ19 Cluster: Serine hydroxymethyltransferase; n=8;
Euryarchaeota|Rep: Serine hydroxymethyltransferase -
Methanopyrus kandleri
Length = 428
Score = 68.9 bits (161), Expect = 5e-11
Identities = 45/149 (30%), Positives = 71/149 (47%), Gaps = 1/149 (0%)
Frame = +2
Query: 29 ESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMA 208
E +P+ D ID D + + +P V++ G S + + + + G Y++
Sbjct: 138 EYLPF--DEEDMAIDVDGMVRKIEEVEPSVVMLGASLFLFPHPVEEAVEAVEAVGGYVVY 195
Query: 209 DMAHVSGLVAAGVIPSPF-EHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYD 385
D AHV GL+A G P E +VT +THKT GP+ G++ ++ D
Sbjct: 196 DAAHVLGLIAGGQFQDPIREGAHVVTGSTHKTFPGPQGGIVLCQR--------------D 241
Query: 386 FEGKINQAVFPGLQGGPHNHAIAAIATAM 472
I++AVFPGL H H +AA+A A+
Sbjct: 242 LADDIDEAVFPGLVSNHHLHHVAALAVAL 270
>UniRef50_Q9HI38 Cluster: Serine hydroxymethyltransferase; n=5;
Thermoplasmatales|Rep: Serine hydroxymethyltransferase -
Thermoplasma acidophilum
Length = 426
Score = 66.5 bits (155), Expect = 3e-10
Identities = 49/142 (34%), Positives = 68/142 (47%), Gaps = 1/142 (0%)
Frame = +2
Query: 38 PYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMA 217
PY +D T ID D+ ++ KP+V + G S + K + E G + D A
Sbjct: 140 PYDMDTMT--IDPDQASKMIIKEKPKVCLFGQSVFMFPAPLKEMAEAFHEVGCKVWYDGA 197
Query: 218 HVSGLVAAGVIPSPF-EHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDFEG 394
HV GL+A G P E DIVT +THKT GP+ GVI + KA
Sbjct: 198 HVLGLIAGGRFQDPLREGADIVTGSTHKTFPGPQHGVILGNTDDETWKA----------- 246
Query: 395 KINQAVFPGLQGGPHNHAIAAI 460
+ +AVFPG+ H +A+AA+
Sbjct: 247 -VRRAVFPGVLSNHHLNAMAAL 267
>UniRef50_Q6L0Q9 Cluster: Serine hydroxymethyltransferase; n=1;
Picrophilus torridus|Rep: Serine
hydroxymethyltransferase - Picrophilus torridus
Length = 377
Score = 65.3 bits (152), Expect = 7e-10
Identities = 38/123 (30%), Positives = 62/123 (50%), Gaps = 1/123 (0%)
Frame = +2
Query: 59 TGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVA 238
+G IDYD + + A+ +P VII G S ++ D KR ++ E + ++ D +HV GL+A
Sbjct: 133 SGSIDYDAMEKIARSERPSVIILGQSEFTMPYDIKRVYDLSREIDSRIIYDASHVLGLIA 192
Query: 239 AGVI-PSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDFEGKINQAVF 415
P + D++ +THKT GP+ G+I K + +M+ F N + F
Sbjct: 193 GRRFQPGALRYSDVLLGSTHKTFFGPQGGIILTNND-EIYKKIEKNIMFKFMDNYNLSRF 251
Query: 416 PGL 424
L
Sbjct: 252 AAL 254
>UniRef50_Q8ZYF9 Cluster: Serine hydroxymethyltransferase; n=5;
Thermoproteaceae|Rep: Serine hydroxymethyltransferase -
Pyrobaculum aerophilum
Length = 430
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/131 (33%), Positives = 61/131 (46%), Gaps = 1/131 (0%)
Frame = +2
Query: 68 IDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVAAGV 247
ID D + + +P +II G S Y + A GAY++ D AHV GL+ GV
Sbjct: 149 IDIDAARKIIEEKRPNLIILGASLYLFPHPVREIANAAKAVGAYVLHDSAHVFGLIIGGV 208
Query: 248 IPSPF-EHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDFEGKINQAVFPGL 424
P+P E ++T++THKT GP+ G+I SV + I +AVFP
Sbjct: 209 FPNPLKEGAHVITSSTHKTFPGPQGGLI------ASVTDE------ELNNAIQRAVFPVF 256
Query: 425 QGGPHNHAIAA 457
H H AA
Sbjct: 257 TSNYHLHRYAA 267
>UniRef50_Q8IKR8 Cluster: Putative uncharacterized protein; n=1;
Plasmodium falciparum 3D7|Rep: Putative uncharacterized
protein - Plasmodium falciparum (isolate 3D7)
Length = 462
Score = 62.1 bits (144), Expect = 6e-09
Identities = 35/119 (29%), Positives = 64/119 (53%), Gaps = 6/119 (5%)
Frame = +2
Query: 71 DYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRF-RQIADENGAY-----LMADMAHVSGL 232
+YD++ + + F P +I S +DY RF + + ++N ++ +M + + L
Sbjct: 168 NYDEIQKISNDFNPDIIYFDESNNPYNIDYDRFIKGLKNKNNKIHNKPIIITNMNNKANL 227
Query: 233 VAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDFEGKINQA 409
++ +I SPF H DIV T ++ R + VIF++KG + V +G + YD+E K+ A
Sbjct: 228 ISQNLINSPFTHSDIVFTYFNENFRAHNSFVIFYKKGYKCVNTDGHIIEYDYEKKLKYA 286
>UniRef50_A0RYP2 Cluster: Glycine/serine hydroxymethyltransferase;
n=2; Thermoprotei|Rep: Glycine/serine
hydroxymethyltransferase - Cenarchaeum symbiosum
Length = 441
Score = 61.3 bits (142), Expect = 1e-08
Identities = 49/149 (32%), Positives = 70/149 (46%), Gaps = 2/149 (1%)
Frame = +2
Query: 29 ESMPYKVDPTTG-LIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLM 205
+SM VD T +ID +K T P++ + G S + K + G ++
Sbjct: 153 KSMTIDVDATKAKIIDLEKAGRT-----PKIAMFGGSLFLFPHPVKELAEFMKGRGMHIN 207
Query: 206 ADMAHVSGLVAAGVIPSPF-EHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMY 382
D AHV+GL+A G P E D +T +THKTL GP+ G++ R+ A G
Sbjct: 208 YDGAHVAGLIAGGQFQDPIREGADTMTMSTHKTLFGPQGGLVL----GRNEHAEG----- 258
Query: 383 DFEGKINQAVFPGLQGGPHNHAIAAIATA 469
I +A+FPGL H H +AA A A
Sbjct: 259 -----IKKAMFPGLTSSHHIHHMAAKAVA 282
>UniRef50_UPI000038E502 Cluster: hypothetical protein Faci_03001668;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03001668 - Ferroplasma acidarmanus fer1
Length = 387
Score = 60.1 bits (139), Expect = 2e-08
Identities = 30/88 (34%), Positives = 49/88 (55%), Gaps = 1/88 (1%)
Frame = +2
Query: 68 IDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVAAGV 247
++YD + E K II G S + + D KR +I +++G ++ D +HV GL+A
Sbjct: 142 LEYDLVEEKIKANNIGTIILGQSMFIKPYDMKRISEICEKHGTKILYDASHVMGLLAGKA 201
Query: 248 I-PSPFEHCDIVTTTTHKTLRGPRAGVI 328
P ++ +IV +THKT GP+ G+I
Sbjct: 202 FQPDALKYSNIVYGSTHKTFFGPQGGII 229
>UniRef50_Q0FXL6 Cluster: Serine hydroxymethyltransferase; n=1;
Fulvimarina pelagi HTCC2506|Rep: Serine
hydroxymethyltransferase - Fulvimarina pelagi HTCC2506
Length = 417
Score = 58.4 bits (135), Expect = 7e-08
Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 1/98 (1%)
Frame = +2
Query: 68 IDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVAAGV 247
+D + AE + KP +++ G S R D E G+ + D +HV+GL+A GV
Sbjct: 162 LDSEAAAEQIRREKPAMVMLGRSVVLRPDDLGPVVAACRETGSLSVYDASHVAGLIAGGV 221
Query: 248 IPSPFE-HCDIVTTTTHKTLRGPRAGVIFFRKGVRSVK 358
+P E D++TT+T+KTL GP ++ R + V+
Sbjct: 222 FLNPLEVGVDLITTSTYKTLAGPTGAIVMGRDPEQGVR 259
>UniRef50_Q0S5S0 Cluster: Glycine hydroxymethyltransferase; n=1;
Rhodococcus sp. RHA1|Rep: Glycine
hydroxymethyltransferase - Rhodococcus sp. (strain RHA1)
Length = 453
Score = 58.0 bits (134), Expect = 1e-07
Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 1/99 (1%)
Frame = +2
Query: 29 ESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMA 208
E +PY P+ ID ++ + +PR+I+ G S + R+ AD GA ++
Sbjct: 167 EHLPYS--PSALDIDAGEIDDFVHRLRPRLIVVGGSVTLFPHNLGPIREAADRVGAVVVY 224
Query: 209 DMAHVSGLVAAGVIPSPF-EHCDIVTTTTHKTLRGPRAG 322
D +H +GL+AAG P E D+VT +T+KT GP G
Sbjct: 225 DASHTAGLIAAGYYQDPLAEGADVVTFSTYKTFAGPAGG 263
>UniRef50_Q0GPG8 Cluster: BZIP transcription factor bZIP94; n=1;
Glycine max|Rep: BZIP transcription factor bZIP94 -
Glycine max (Soybean)
Length = 230
Score = 58.0 bits (134), Expect = 1e-07
Identities = 23/36 (63%), Positives = 30/36 (83%)
Frame = +2
Query: 368 QKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
Q+V+YD++ KINQ VFPGLQGGP+NH I +A A+K
Sbjct: 157 QQVLYDYKDKINQPVFPGLQGGPYNHTIIGLAVALK 192
>UniRef50_Q9TSA5 Cluster: Serine hydroxymethyltransferase; n=1; Ovis
aries|Rep: Serine hydroxymethyltransferase - Ovis aries
(Sheep)
Length = 150
Score = 56.4 bits (130), Expect = 3e-07
Identities = 25/44 (56%), Positives = 32/44 (72%)
Frame = +2
Query: 47 VDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQI 178
V+P TG IDYD+L E A+LF P++IIAG SCYSR F+Q+
Sbjct: 54 VNPDTGYIDYDQLEENARLFHPKLIIAGTSCYSRQAMTPEFKQV 97
>UniRef50_A0GN01 Cluster: Glycine hydroxymethyltransferase; n=1;
Burkholderia phytofirmans PsJN|Rep: Glycine
hydroxymethyltransferase - Burkholderia phytofirmans
PsJN
Length = 358
Score = 54.8 bits (126), Expect = 9e-07
Identities = 43/146 (29%), Positives = 69/146 (47%), Gaps = 1/146 (0%)
Frame = +2
Query: 35 MPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADM 214
+PY V G I+ D+ A A+ +P V GM+ L + + I E G + D
Sbjct: 78 IPYSVKD--GSINLDEFATIARKERPAVTGLGMTLTLFPLPIREIKAIVSEWGGLVYFDG 135
Query: 215 AHVSGLVAAGVIPSPF-EHCDIVTTTTHKTLRGPRAGVIFFRKGVRSVKANGQKVMYDFE 391
AH GL++AG+ P E D++T ++ KT GP+ G+I + N ++
Sbjct: 136 AHQLGLISAGLFQDPLGEGADVMTGSSGKTFSGPQGGIICW---------NTDRL----A 182
Query: 392 GKINQAVFPGLQGGPHNHAIAAIATA 469
I + +FP L G + +AA+A A
Sbjct: 183 DTIAETIFPVLTGSHQINRVAALAVA 208
>UniRef50_Q7RRP9 Cluster: Serine hydroxymethyltransferase,
mitochondrial; n=4; Plasmodium (Vinckeia)|Rep: Serine
hydroxymethyltransferase, mitochondrial - Plasmodium
yoelii yoelii
Length = 484
Score = 54.0 bits (124), Expect = 2e-06
Identities = 23/100 (23%), Positives = 53/100 (53%)
Frame = +2
Query: 176 IADENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGVRSV 355
+ D+N ++ ++++ + + I SPF DIV + ++ +R +IF+RKG +++
Sbjct: 232 VEDKNNTLVITNISNKASFIIGNFISSPFSQADIVFSYLNENIRANNCYIIFYRKGFKNI 291
Query: 356 KANGQKVMYDFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
G+ + Y++E + + F N+ I +++T+ K
Sbjct: 292 STQGKLICYEYEDNLKKTYFQ----NNVNNIICSLSTSFK 327
>UniRef50_Q5C0V4 Cluster: SJCHGC07535 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07535 protein - Schistosoma
japonicum (Blood fluke)
Length = 218
Score = 53.6 bits (123), Expect = 2e-06
Identities = 22/31 (70%), Positives = 27/31 (87%)
Frame = +2
Query: 383 DFEGKINQAVFPGLQGGPHNHAIAAIATAMK 475
DFE +IN+AVFPGLQGGPHN+ IAA+A +K
Sbjct: 23 DFERRINEAVFPGLQGGPHNNTIAAMAVCLK 53
>UniRef50_Q28QL6 Cluster: Glycine hydroxymethyltransferase; n=7;
Rhodobacteraceae|Rep: Glycine hydroxymethyltransferase -
Jannaschia sp. (strain CCS1)
Length = 445
Score = 52.0 bits (119), Expect = 6e-06
Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 6/100 (6%)
Frame = +2
Query: 47 VDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVS 226
V P ID LA+ A +P +I G S R IAD+ GAYL+ D AH
Sbjct: 169 VYPNCYTIDIPGLADLAAKERPALITLGGSLNLLPHPVAEVRAIADDVGAYLLMDAAHQC 228
Query: 227 GLVAAGVIPSPF------EHCDIVTTTTHKTLRGPRAGVI 328
GL A P P E ++T +T+K+L GP G+I
Sbjct: 229 GLFAGQAWPDPLASENGAEGAHLMTMSTYKSLGGPAGGLI 268
>UniRef50_UPI0000DAE560 Cluster: hypothetical protein
Rgryl_01000619; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000619 - Rickettsiella
grylli
Length = 442
Score = 41.9 bits (94), Expect = 0.007
Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 5/102 (4%)
Frame = +2
Query: 68 IDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIAD--ENGAYLMADMAHVSGLVAA 241
I+Y + K KP ++ + + + K+ R+I D + D +H++GL+
Sbjct: 151 INYIAFEDILKKVKPSLVYIDQATFLFPISVKKMREIIDIVSPSTIIHYDSSHINGLIFG 210
Query: 242 GVIPSPFE---HCDIVTTTTHKTLRGPRAGVIFFRKGVRSVK 358
GV +P + HC +THKT GP G + + S K
Sbjct: 211 GVCNNPLDEGAHC--FGGSTHKTFPGPHKGFLATNDPILSKK 250
>UniRef50_O33942 Cluster: EryCIV; n=11; Actinomycetales|Rep: EryCIV
- Saccharopolyspora erythraea (Streptomyces erythraeus)
Length = 401
Score = 38.7 bits (86), Expect = 0.065
Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 1/101 (0%)
Frame = +2
Query: 47 VDPTTGLIDYDKLAETAKLFKPRV-IIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHV 223
VDP TGL+D + A L PR I G+ + R + +IA E+ L D AH
Sbjct: 119 VDPETGLLDPE---HVASLVTPRTGAIIGVHLWGRPAPVEALEKIAAEHQVKLFFDAAHA 175
Query: 224 SGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFRKGV 346
G A G F + ++ + K + G I G+
Sbjct: 176 LGCTAGGRPVGAFGNAEVFSFHATKAVTSFEGGAIVTDDGL 216
>UniRef50_Q0AVP5 Cluster: Selenocysteine lyase; n=2;
Clostridiales|Rep: Selenocysteine lyase - Syntrophomonas
wolfei subsp. wolfei (strain Goettingen)
Length = 382
Score = 37.5 bits (83), Expect = 0.15
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +2
Query: 161 KRFRQIADENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPR-AGVIFFR 337
K QIA ENG M D A +G++ V F+ DI+ T HK L GP+ G I+ R
Sbjct: 159 KTIGQIARENGILFMLDTAQTAGVLRIDV--EEFK-IDILAFTGHKGLLGPQGTGGIYLR 215
Query: 338 KGV 346
G+
Sbjct: 216 PGI 218
>UniRef50_Q3A5G7 Cluster: Pyridoxal-phosphate-dependent
aminotransferase enzyme; n=1; Pelobacter carbinolicus
DSM 2380|Rep: Pyridoxal-phosphate-dependent
aminotransferase enzyme - Pelobacter carbinolicus
(strain DSM 2380 / Gra Bd 1)
Length = 379
Score = 36.7 bits (81), Expect = 0.26
Identities = 25/66 (37%), Positives = 32/66 (48%)
Frame = +2
Query: 47 VDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVS 226
VDP T LID + E+ + R I+A C DY RQIA +G YL++D H
Sbjct: 103 VDPQTLLIDPASV-ESRITARTRAIVAVDYAGQPC-DYDTLRQIASHHGLYLISDACHSL 160
Query: 227 GLVAAG 244
G G
Sbjct: 161 GAAWRG 166
>UniRef50_Q8GGQ5 Cluster: Serine hydroxymethyltransferase; n=1;
Streptomyces atroolivaceus|Rep: Serine
hydroxymethyltransferase - Streptomyces atroolivaceus
Length = 447
Score = 36.7 bits (81), Expect = 0.26
Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Frame = +2
Query: 53 PTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADEN--GAYLMADMAHVS 226
P +D + AE +P ++ S +D K + E G + D +H
Sbjct: 147 PDPHSLDLEHAAELLARVRPSLVYVDQSHCLFPVDVKSLVETVREASPGTLVHVDASHWL 206
Query: 227 GLVAAGVIPSPFEH-CDIVTTTTHKTLRGPRAGVIFFR 337
GLV P+P + D +THKT GP+ V+ R
Sbjct: 207 GLVLGDAFPNPLDQGADSWGGSTHKTFPGPQKAVVLTR 244
>UniRef50_Q5KZ59 Cluster: Aminotransferase; n=10; Bacteria|Rep:
Aminotransferase - Geobacillus kaustophilus
Length = 499
Score = 35.9 bits (79), Expect = 0.46
Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 8/104 (7%)
Frame = +2
Query: 47 VDPT-TGLIDYDKLAETAKLFK--PRVIIAGMSCYSRC---LDYKRFRQIADENGAYLMA 208
V PT G +D D L E + ++ P+ I A +C + Y + +I E+G
Sbjct: 173 VRPTENGDVDLDHLRELLERYRDRPQKIGAFTACSNVTGLETPYHKLAKIMHEHGGLCFV 232
Query: 209 DMAHVSGLVAAGVIPS-PFEHCDIVTTTTHKTLRGP-RAGVIFF 334
D A + V + P P E D + + HK L GP AGV+ F
Sbjct: 233 DFAASAPYVRIDMHPDDPMEQLDAIYFSPHKFLGGPGSAGVLIF 276
>UniRef50_A6RBG5 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 417
Score = 35.9 bits (79), Expect = 0.46
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Frame = +2
Query: 26 FESMPYK-VDPTTGLID--YDKLAETAKLFKPRVIIAGMSCYSRCLDYKRF-RQIADENG 193
F PY +D T +++ + + + A LF+P G C + ++ RF RQ+ADE+
Sbjct: 127 FVIAPYNNIDETRAIVNSLHPRSSLAAILFEPMQGAGG--CRTATKEFARFLRQVADEHS 184
Query: 194 AYLMADMAHVSGLVAAGV 247
A L+AD S L AG+
Sbjct: 185 ALLIADEVMTSRLAPAGL 202
>UniRef50_Q2RVH6 Cluster: Aminotransferase, class V; n=3;
Bacteria|Rep: Aminotransferase, class V - Rhodospirillum
rubrum (strain ATCC 11170 / NCIB 8255)
Length = 393
Score = 35.5 bits (78), Expect = 0.60
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 5/100 (5%)
Frame = +2
Query: 62 GLIDYDKLAETAKLFKPRVIIAGMSCYSRCLD----YKRFRQIADENGAYLMADMAHVSG 229
G +D D+LA A +P + + + + + + Q+A ENGA D +G
Sbjct: 126 GTVDPDRLA-LAFARRPAIALVSVMAANNVVGTLQALEDLGQVAHENGALFHTDAIQAAG 184
Query: 230 LVAAGVIPSPFEHCDIVTTTTHKTLRGPR-AGVIFFRKGV 346
VA V P D+++ + HK L GP+ G ++ R GV
Sbjct: 185 KVAIDVRTLP---VDMLSLSAHK-LHGPKGVGALYLRPGV 220
>UniRef50_A0Y9H9 Cluster: DegT/DnrJ/EryC1/StrS aminotransferase;
n=1; marine gamma proteobacterium HTCC2143|Rep:
DegT/DnrJ/EryC1/StrS aminotransferase - marine gamma
proteobacterium HTCC2143
Length = 367
Score = 35.1 bits (77), Expect = 0.80
Identities = 28/100 (28%), Positives = 39/100 (39%)
Frame = +2
Query: 5 ISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIAD 184
+ +S+ +P D T I D A+ A + R II G+ Y + R+ D
Sbjct: 94 LPVSSVGATVVPVATDLETYCISIDA-AKKAVTDRTRAII-GVHLYGHPFEAVELRKFCD 151
Query: 185 ENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTL 304
E G YL+ D A G G F H + KTL
Sbjct: 152 EKGIYLVEDCAQAHGATLGGRKVGSFGHAAAFSFYPTKTL 191
>UniRef50_Q0UBV4 Cluster: Predicted protein; n=1; Phaeosphaeria
nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
(Septoria nodorum)
Length = 302
Score = 35.1 bits (77), Expect = 0.80
Identities = 21/52 (40%), Positives = 27/52 (51%)
Frame = +1
Query: 274 HRNNNYTQNTAGSSRWGHILPQGSSLGQSERAESDVRFRREDQPGRIPGASG 429
H N YTQ T ++ +G P GS G+ R S R R+D PG +PG G
Sbjct: 122 HTNYEYTQTTPTTNMYGRGNPYGS--GRRGRGRSG-RDGRQDPPGMMPGYPG 170
>UniRef50_Q9KVA5 Cluster: Perosamine synthase; n=7; Vibrio
cholerae|Rep: Perosamine synthase - Vibrio cholerae
Length = 367
Score = 34.3 bits (75), Expect = 1.4
Identities = 18/77 (23%), Positives = 31/77 (40%)
Frame = +2
Query: 98 KLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVAAGVIPSPFEHCDI 277
K+ K + + Y + D + R + DE+G YL+ D A G G F
Sbjct: 115 KINKKTKAVMAVHIYGQACDIQSLRDLCDEHGLYLIEDCAEAIGTAVNGKKVGTFGDVST 174
Query: 278 VTTTTHKTLRGPRAGVI 328
+ +KT+ G++
Sbjct: 175 FSFFGNKTITSGEGGMV 191
>UniRef50_Q8YZC3 Cluster: DegT/DnrJ/EryC1/StrS family; n=7;
Bacteria|Rep: DegT/DnrJ/EryC1/StrS family - Anabaena sp.
(strain PCC 7120)
Length = 406
Score = 33.9 bits (74), Expect = 1.8
Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Frame = +2
Query: 47 VDPTTGLIDYDKLAETAKLFKPRVI-IAGMSCYSRCLDYKRFRQIADENGAYLMADMAHV 223
+DP T ID +K+ ++ PR I G+ + R + + +IAD + LM D AH
Sbjct: 119 IDPHTHNIDPNKIVQS---ITPRTTGIIGVHLWGRPCNVEALSEIADTHNLKLMFDAAHA 175
Query: 224 SGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVI 328
G G + F ++ + K L G I
Sbjct: 176 FGCSHQGRMIGSFGDAEVFSFHATKFLNTFEGGAI 210
>UniRef50_A4E729 Cluster: Putative uncharacterized protein; n=4;
Bacteria|Rep: Putative uncharacterized protein -
Collinsella aerofaciens ATCC 25986
Length = 379
Score = 33.5 bits (73), Expect = 2.4
Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 5/144 (3%)
Frame = +2
Query: 56 TTGLIDYDKLAETAKLFKPRVIIAGMSCYS-RCLDYKRFRQIADENGAYLMADMAHVSGL 232
T G++DYD+L V++ S + +D R +A GA ++ D + +G
Sbjct: 121 TNGVLDYDELERLVTPGTRAVVVTHASNVTGNAVDIARVAAMAHAAGALVIVDASQSAGT 180
Query: 233 VAAGVIPSPFEHCDIVTTTTHKTLRGPR-AGVIFFRKGVRSVK-ANGQKVMYDFEGKINQ 406
I D+V T HK L GP+ G + +G+ A G ++ F+ +
Sbjct: 181 AK---IDMDAMGLDVVCFTGHKGLMGPQGTGGLAVAEGIDVAPWAMGGTGVHSFDA-LQP 236
Query: 407 AVFP-GLQGGPHN-HAIAAIATAM 472
+P L+ G N H IA ++ +
Sbjct: 237 LEWPTRLEAGTLNGHGIAGLSAGL 260
>UniRef50_Q8TXP1 Cluster: UPF0425 pyridoxal phosphate-dependent
protein MK0620; n=1; Methanopyrus kandleri|Rep: UPF0425
pyridoxal phosphate-dependent protein MK0620 -
Methanopyrus kandleri
Length = 346
Score = 33.5 bits (73), Expect = 2.4
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
Frame = +2
Query: 116 VIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTH 295
V++ G + R++A L+ D + G P P D+V T+
Sbjct: 146 VVVTGCDVRWNVVSEDTLREVASAEAVTLLDDASGDRVRRLHGQKPGPRYGFDLVVTSCD 205
Query: 296 KTLRGPRAGVIFFR----KGVRSV 355
K + GPRAGV+ R +GVR V
Sbjct: 206 KLMDGPRAGVLIGRDDLVEGVRRV 229
>UniRef50_A0C8P8 Cluster: Chromosome undetermined scaffold_159,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_159,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 384
Score = 33.1 bits (72), Expect = 3.2
Identities = 11/29 (37%), Positives = 19/29 (65%)
Frame = +2
Query: 386 FEGKINQAVFPGLQGGPHNHAIAAIATAM 472
+ ++++A +PG Q GPH H I IA ++
Sbjct: 229 YSEEVDEACYPGYQSGPHFHTITGIAVSL 257
>UniRef50_Q5ACU5 Cluster: Putative uncharacterized protein PIB1;
n=1; Candida albicans|Rep: Putative uncharacterized
protein PIB1 - Candida albicans (Yeast)
Length = 362
Score = 32.7 bits (71), Expect = 4.3
Identities = 20/64 (31%), Positives = 27/64 (42%)
Frame = -1
Query: 331 EYDPSARTPQCFVCSCCYDVTMFKRTWNYTCCNKA*HVCHVCHQVGAIFISYLSESLIVE 152
E+ A CF+C Y++ F R + C K VC + FISY + IV
Sbjct: 13 EWQDDAEVTSCFICDRPYNI-FFNRRHHCRKCGKV-----VCGDCSSQFISYFPNTPIVT 66
Query: 151 TPRV 140
P V
Sbjct: 67 EPHV 70
>UniRef50_UPI0000384B0D Cluster: COG0399: Predicted pyridoxal
phosphate-dependent enzyme apparently involved in
regulation of cell wall biogenesis; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0399:
Predicted pyridoxal phosphate-dependent enzyme
apparently involved in regulation of cell wall
biogenesis - Magnetospirillum magnetotacticum MS-1
Length = 356
Score = 32.3 bits (70), Expect = 5.6
Identities = 20/56 (35%), Positives = 28/56 (50%)
Frame = +2
Query: 170 RQIADENGAYLMADMAHVSGLVAAGVIPSPFEHCDIVTTTTHKTLRGPRAGVIFFR 337
R +AD++GA L+ D AH A +P E D+V + HK L P V+ R
Sbjct: 124 RALADKHGALLVEDAAH-----ALAPVPGIGEAGDVVLYSPHKLLALPDGAVVVVR 174
>UniRef50_Q85302 Cluster: Homologue of retroviral pseudoprotease;
n=1; Orf virus|Rep: Homologue of retroviral
pseudoprotease - Orf virus
Length = 351
Score = 32.3 bits (70), Expect = 5.6
Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 9/98 (9%)
Frame = +1
Query: 190 WRLLDGRHGTRVRPCCSRCNS--KSF*TL*HRNNNYTQNTAGSSRWGHILPQGSSLGQSE 363
WRL GR VR C R ++ +SF TL R A +R G LP+ ++ G+
Sbjct: 164 WRLAGGRRVWGVRGCGGRVSTARRSFFTL-LRGAWSGARAAAGARAGGPLPRRAARGRQR 222
Query: 364 RAE-SDVRFRREDQP-GRIPGAS-----GRSSQPRHSR 456
R + R RR QP R P A+ GR PR +
Sbjct: 223 RGQPPPPRARRAQQPRRRAPRAAAGARRGRGPAPRQQQ 260
>UniRef50_O67617 Cluster: Transcriptional regulator; n=2; Aquifex
aeolicus|Rep: Transcriptional regulator - Aquifex
aeolicus
Length = 346
Score = 32.3 bits (70), Expect = 5.6
Identities = 15/54 (27%), Positives = 29/54 (53%)
Frame = +2
Query: 68 IDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENGAYLMADMAHVSG 229
+D ++L + K ++PRV+I + Y + D + +AD G +++ D A G
Sbjct: 106 MDVNQLEDAVKKYRPRVVIP-VHLYGQPADMENIMFLADRYGFFVLEDCAQAHG 158
>UniRef50_A7DGE7 Cluster: DegT/DnrJ/EryC1/StrS aminotransferase;
n=1; Methylobacterium extorquens PA1|Rep:
DegT/DnrJ/EryC1/StrS aminotransferase - Methylobacterium
extorquens PA1
Length = 394
Score = 32.3 bits (70), Expect = 5.6
Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 20 IFFESMPYKVDPTTGLIDYDKLAETAKLFKPR---VIIAGMSCYSRCLDYKRFRQIADEN 190
++ + P +D + + L + A PR VI+ + Y +D + +R ADE
Sbjct: 112 LYVGATPVFIDIASMGLPLMSLEDAAAKCTPRTRAVILVHFAGY--LVDPEPWRAFADER 169
Query: 191 GAYLMADMAHVSGLVAAGVI 250
G L+ D AH +GL AG +
Sbjct: 170 GLVLIEDAAHAAGLSGAGTL 189
>UniRef50_A4AP52 Cluster: Perosamine synthetase; n=1;
Flavobacteriales bacterium HTCC2170|Rep: Perosamine
synthetase - Flavobacteriales bacterium HTCC2170
Length = 363
Score = 32.3 bits (70), Expect = 5.6
Identities = 21/75 (28%), Positives = 36/75 (48%)
Frame = +2
Query: 5 ISATSIFFESMPYKVDPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIAD 184
+ AT IF + P+ + LI+ AK+ I + Y ++Y + ++IAD
Sbjct: 95 VGATPIFVDIDPFSWNLDPSLIE-------AKISSRTKAILYTNVYGAPVEYNKLKRIAD 147
Query: 185 ENGAYLMADMAHVSG 229
++G YL+ D A G
Sbjct: 148 KHGIYLIEDAAESFG 162
>UniRef50_O10368 Cluster: Early 53 kDa protein; n=8;
Nucleopolyhedrovirus|Rep: Early 53 kDa protein - Orgyia
pseudotsugata multicapsid polyhedrosis virus (OpMNPV)
Length = 455
Score = 32.3 bits (70), Expect = 5.6
Identities = 13/24 (54%), Positives = 15/24 (62%)
Frame = -1
Query: 352 RANSLAEEYDPSARTPQCFVCSCC 281
RA S EE+ PS TP CF +CC
Sbjct: 180 RAASADEEFVPSPNTPDCFEFACC 203
>UniRef50_A5FNU5 Cluster: TonB-dependent receptor; n=1;
Flavobacterium johnsoniae UW101|Rep: TonB-dependent
receptor - Flavobacterium johnsoniae UW101
Length = 607
Score = 31.9 bits (69), Expect = 7.4
Identities = 22/70 (31%), Positives = 31/70 (44%)
Frame = -1
Query: 466 SRYRGYGVVVRTALKPREYGLVDLPFEIVHHFLPVRFDRANSLAEEYDPSARTPQCFVCS 287
SR +GYG + RE G L ++HH L ++D S+ +E + P F
Sbjct: 318 SRNKGYGSSIDNV--KREVGTASL---LLHHLLTEKWDYNASIRQEITDNYGNPFLFSFG 372
Query: 286 CCYDVTMFKR 257
YD T F R
Sbjct: 373 TKYDFTSFYR 382
>UniRef50_Q6K9D9 Cluster: Putative uncharacterized protein
OJ1471_E11.21; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
OJ1471_E11.21 - Oryza sativa subsp. japonica (Rice)
Length = 304
Score = 31.9 bits (69), Expect = 7.4
Identities = 17/45 (37%), Positives = 23/45 (51%)
Frame = -3
Query: 461 LSRLWRGCEDRPEAPGIRPG*SSLRNRTSLSARSL*PSELPCGRI 327
L R R C R + +RPG SS + +S +A L PS P G +
Sbjct: 169 LPRRHRACLRRDRSRSLRPGRSSSSSSSSTAAADLGPSSSPSGHV 213
>UniRef50_UPI0000584CE3 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 584
Score = 31.5 bits (68), Expect = 9.8
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = -2
Query: 375 TFCPFALTERTPLRKNMTPARGPRSVLCVVVVTMSQCSKGLGI---TPAATRPDTCAM 211
T CP + +R+ +RK+MT G + C V T ++GL + T +P C++
Sbjct: 238 TLCPKSFAQRSGVRKHMTIHSGEKPYQCTVCQTSFARTEGLAVHMRTHTKEQPFQCSV 295
>UniRef50_A6X7T2 Cluster: Diguanylate cyclase precursor; n=1;
Ochrobactrum anthropi ATCC 49188|Rep: Diguanylate
cyclase precursor - Ochrobactrum anthropi (strain ATCC
49188 / DSM 6882 / NCTC 12168)
Length = 231
Score = 31.5 bits (68), Expect = 9.8
Identities = 16/48 (33%), Positives = 22/48 (45%)
Frame = +2
Query: 50 DPTTGLIDYDKLAETAKLFKPRVIIAGMSCYSRCLDYKRFRQIADENG 193
D TGL+ E + I+AG + LD F+QI D+NG
Sbjct: 66 DVLTGLLSRSAFRERGQKLLRESIVAGRDLTAMMLDIDHFKQINDQNG 113
>UniRef50_A0LTD4 Cluster: Major facilitator superfamily MFS_1; n=1;
Acidothermus cellulolyticus 11B|Rep: Major facilitator
superfamily MFS_1 - Acidothermus cellulolyticus (strain
ATCC 43068 / 11B)
Length = 442
Score = 31.5 bits (68), Expect = 9.8
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = -2
Query: 396 FPSKSYITFCPFALTERTPLRKNMT-PARGPRSVLCVVVVTMSQCSKGLGITPAATRPD 223
+P +S + FC A T L MT +R P +VL VV+ S CS ++T PD
Sbjct: 99 YPRRSVLLFCDLARAVLTLLLLAMTFDSRIPIAVLLAVVLLASFCSPPFVTARSSTIPD 157
>UniRef50_Q5BGG2 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 1411
Score = 31.5 bits (68), Expect = 9.8
Identities = 21/88 (23%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = -1
Query: 367 PVRFDRANSLAEEYDPSARTPQCFVCSCCYDVTMFKRTWNYTCC--NKA*HVCHVCHQVG 194
P++ + L+ P R QC C C YD + + C +K H C V
Sbjct: 351 PLQLFGLSGLSRPTRPKQRPLQCTRCYCFYDTRACRSSERCISCGSSKQEHNCRRGGAVH 410
Query: 193 AIFISYLSESLIVETPRVTTHTGDYYTR 110
+ +S+ ++ ++V+ P T+T + T+
Sbjct: 411 DLLLSFEADIILVQEP--WTNTAKHLTK 436
>UniRef50_Q8PWQ9 Cluster: Cysteine desulfurase; n=5;
Euryarchaeota|Rep: Cysteine desulfurase - Methanosarcina
mazei (Methanosarcina frisia)
Length = 393
Score = 31.5 bits (68), Expect = 9.8
Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Frame = +2
Query: 62 GLIDYDKLAETAKLFKPRVIIAG--MSCYSRCLDYKRFRQIADENGAYLMADMAHVSGLV 235
G+ID ++ E A + ++I + + + R ++A +NG ++ D A +G V
Sbjct: 138 GIID-PRMIENALTDRTKLIAVTHISNVFGSVQNVSRITKLARKNGVKILVDGAQSAGHV 196
Query: 236 AAGVIPSPFEHCDIVTTTTHKTLRGPR-AGVIFFR 337
+ CD T HK L GP+ GV++ +
Sbjct: 197 PVNIKTLG---CDFFATAGHKGLLGPQGTGVLYIK 228
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 488,077,490
Number of Sequences: 1657284
Number of extensions: 9724298
Number of successful extensions: 28820
Number of sequences better than 10.0: 86
Number of HSP's better than 10.0 without gapping: 27908
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28749
length of database: 575,637,011
effective HSP length: 94
effective length of database: 419,852,315
effective search space used: 26450695845
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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