Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0002_M04
(531 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U49283-1|AAB94295.1| 385|Homo sapiens NAD+-specific isocitrate ... 251 1e-66
BC001960-1|AAH01960.1| 385|Homo sapiens isocitrate dehydrogenas... 251 1e-66
AL050094-1|CAB43266.1| 259|Homo sapiens hypothetical protein pr... 251 1e-66
AL049712-2|CAC01443.1| 383|Homo sapiens isocitrate dehydrogenas... 251 1e-66
AL049712-1|CAC01442.2| 385|Homo sapiens isocitrate dehydrogenas... 251 1e-66
AF023266-1|AAD09340.1| 387|Homo sapiens NAD+-specific isocitrat... 251 1e-66
AF023265-1|AAD09339.1| 383|Homo sapiens NAD+-specific isocitrat... 251 1e-66
Z68907-1|CAA93143.1| 393|Homo sapiens NAD (H)-specific isocitra... 212 6e-55
Z68129-1|CAA92214.1| 393|Homo sapiens NAD(H)-specific isocitrat... 212 6e-55
U40272-1|AAD09357.1| 393|Homo sapiens NAD+-specific isocitrate ... 212 6e-55
BC000933-1|AAH00933.1| 393|Homo sapiens isocitrate dehydrogenas... 212 6e-55
U69268-1|AAB70115.1| 296|Homo sapiens NAD (H)-specific isocitra... 211 1e-54
BC001902-1|AAH01902.1| 393|Homo sapiens isocitrate dehydrogenas... 210 3e-54
AK001905-1|BAA91971.1| 233|Homo sapiens protein ( Homo sapiens ... 194 2e-49
U07681-1|AAA85639.1| 366|Homo sapiens NAD(H)-specific isocitrat... 146 4e-35
BC021967-1|AAH21967.1| 366|Homo sapiens isocitrate dehydrogenas... 146 4e-35
AL442090-1|CAC09449.1| 288|Homo sapiens hypothetical protein pr... 146 4e-35
AK222973-1|BAD96693.1| 366|Homo sapiens isocitrate dehydrogenas... 146 6e-35
U69269-1|AAB70116.1| 210|Homo sapiens NAD (H)-specific isocitra... 135 8e-32
AK093338-1|BAC04136.1| 355|Homo sapiens protein ( Homo sapiens ... 125 1e-28
AF046929-1|AAF20164.1| 156|Homo sapiens NAD+-specific isocitrat... 104 2e-22
AB209206-1|BAD92443.1| 174|Homo sapiens isocitrate dehydrogenas... 96 8e-20
>U49283-1|AAB94295.1| 385|Homo sapiens NAD+-specific isocitrate
dehydrogenase beta precursor protein.
Length = 385
Score = 251 bits (614), Expect = 1e-66
Identities = 118/176 (67%), Positives = 136/176 (77%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NVVHVKSLP RH+++D +IIREQTEGEYS+LEHES GV+ECLKI+T AKS+RIAKF
Sbjct: 141 NVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKF 200
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AFDYA K GR KVTAVHKANIMKLGDGLFL+ CEE+A+LYP+I+FE MI+DNC MQ+V N
Sbjct: 201 AFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 260
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARHIFSGAVG 530
P QFDV+V PNLYGNI+DN E AVFE GARH F+ AVG
Sbjct: 261 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG 316
>BC001960-1|AAH01960.1| 385|Homo sapiens isocitrate dehydrogenase 3
(NAD+) beta protein.
Length = 385
Score = 251 bits (614), Expect = 1e-66
Identities = 118/176 (67%), Positives = 136/176 (77%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NVVHVKSLP RH+++D +IIREQTEGEYS+LEHES GV+ECLKI+T AKS+RIAKF
Sbjct: 141 NVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKF 200
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AFDYA K GR KVTAVHKANIMKLGDGLFL+ CEE+A+LYP+I+FE MI+DNC MQ+V N
Sbjct: 201 AFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 260
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARHIFSGAVG 530
P QFDV+V PNLYGNI+DN E AVFE GARH F+ AVG
Sbjct: 261 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG 316
>AL050094-1|CAB43266.1| 259|Homo sapiens hypothetical protein
protein.
Length = 259
Score = 251 bits (614), Expect = 1e-66
Identities = 118/176 (67%), Positives = 136/176 (77%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NVVHVKSLP RH+++D +IIREQTEGEYS+LEHES GV+ECLKI+T AKS+RIAKF
Sbjct: 15 NVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKF 74
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AFDYA K GR KVTAVHKANIMKLGDGLFL+ CEE+A+LYP+I+FE MI+DNC MQ+V N
Sbjct: 75 AFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 134
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARHIFSGAVG 530
P QFDV+V PNLYGNI+DN E AVFE GARH F+ AVG
Sbjct: 135 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG 190
>AL049712-2|CAC01443.1| 383|Homo sapiens isocitrate dehydrogenase 3
(NAD+) beta protein.
Length = 383
Score = 251 bits (614), Expect = 1e-66
Identities = 118/176 (67%), Positives = 136/176 (77%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NVVHVKSLP RH+++D +IIREQTEGEYS+LEHES GV+ECLKI+T AKS+RIAKF
Sbjct: 141 NVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKF 200
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AFDYA K GR KVTAVHKANIMKLGDGLFL+ CEE+A+LYP+I+FE MI+DNC MQ+V N
Sbjct: 201 AFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 260
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARHIFSGAVG 530
P QFDV+V PNLYGNI+DN E AVFE GARH F+ AVG
Sbjct: 261 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG 316
>AL049712-1|CAC01442.2| 385|Homo sapiens isocitrate dehydrogenase 3
(NAD+) beta protein.
Length = 385
Score = 251 bits (614), Expect = 1e-66
Identities = 118/176 (67%), Positives = 136/176 (77%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NVVHVKSLP RH+++D +IIREQTEGEYS+LEHES GV+ECLKI+T AKS+RIAKF
Sbjct: 141 NVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKF 200
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AFDYA K GR KVTAVHKANIMKLGDGLFL+ CEE+A+LYP+I+FE MI+DNC MQ+V N
Sbjct: 201 AFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 260
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARHIFSGAVG 530
P QFDV+V PNLYGNI+DN E AVFE GARH F+ AVG
Sbjct: 261 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG 316
>AF023266-1|AAD09340.1| 387|Homo sapiens NAD+-specific isocitrate
dehydrogenase beta subunit isoform B protein.
Length = 387
Score = 251 bits (614), Expect = 1e-66
Identities = 118/176 (67%), Positives = 136/176 (77%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NVVHVKSLP RH+++D +IIREQTEGEYS+LEHES GV+ECLKI+T AKS+RIAKF
Sbjct: 141 NVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKF 200
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AFDYA K GR KVTAVHKANIMKLGDGLFL+ CEE+A+LYP+I+FE MI+DNC MQ+V N
Sbjct: 201 AFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 260
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARHIFSGAVG 530
P QFDV+V PNLYGNI+DN E AVFE GARH F+ AVG
Sbjct: 261 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG 316
>AF023265-1|AAD09339.1| 383|Homo sapiens NAD+-specific isocitrate
dehydrogenase beta subunit isoform A protein.
Length = 383
Score = 251 bits (614), Expect = 1e-66
Identities = 118/176 (67%), Positives = 136/176 (77%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NVVHVKSLP RH+++D +IIREQTEGEYS+LEHES GV+ECLKI+T AKS+RIAKF
Sbjct: 141 NVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKF 200
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AFDYA K GR KVTAVHKANIMKLGDGLFL+ CEE+A+LYP+I+FE MI+DNC MQ+V N
Sbjct: 201 AFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 260
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARHIFSGAVG 530
P QFDV+V PNLYGNI+DN E AVFE GARH F+ AVG
Sbjct: 261 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG 316
>Z68907-1|CAA93143.1| 393|Homo sapiens NAD (H)-specific isocitrate
dehydrogenase gamma subunit precursor protein.
Length = 393
Score = 212 bits (518), Expect = 6e-55
Identities = 106/169 (62%), Positives = 120/169 (71%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NV+H KSLP V RH D+D +I+RE TEGEYS+LEHESV GVVE LKIIT AKS RIA++
Sbjct: 144 NVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEY 203
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AF A + GRKKVTAVHKANIMKLGDGLFL+ C E+A YP+I FE MIVDN TMQ+VS
Sbjct: 204 AFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSR 263
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARH 509
P QFDVMV PNLYGNIV+N AVFE R+
Sbjct: 264 PQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRN 312
>Z68129-1|CAA92214.1| 393|Homo sapiens NAD(H)-specific isocitrate
dehydrogenase gamma-subunit precursor protein.
Length = 393
Score = 212 bits (518), Expect = 6e-55
Identities = 106/169 (62%), Positives = 120/169 (71%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NV+H KSLP V RH D+D +I+RE TEGEYS+LEHESV GVVE LKIIT AKS RIA++
Sbjct: 144 NVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEY 203
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AF A + GRKKVTAVHKANIMKLGDGLFL+ C E+A YP+I FE MIVDN TMQ+VS
Sbjct: 204 AFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSR 263
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARH 509
P QFDVMV PNLYGNIV+N AVFE R+
Sbjct: 264 PQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRN 312
>U40272-1|AAD09357.1| 393|Homo sapiens NAD+-specific isocitrate
dehydrogenase gamma subunit precursor protein.
Length = 393
Score = 212 bits (518), Expect = 6e-55
Identities = 106/169 (62%), Positives = 120/169 (71%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NV+H KSLP V RH D+D +I+RE TEGEYS+LEHESV GVVE LKIIT AKS RIA++
Sbjct: 144 NVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEY 203
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AF A + GRKKVTAVHKANIMKLGDGLFL+ C E+A YP+I FE MIVDN TMQ+VS
Sbjct: 204 AFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSR 263
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARH 509
P QFDVMV PNLYGNIV+N AVFE R+
Sbjct: 264 PQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRN 312
>BC000933-1|AAH00933.1| 393|Homo sapiens isocitrate dehydrogenase 3
(NAD+) gamma protein.
Length = 393
Score = 212 bits (518), Expect = 6e-55
Identities = 106/169 (62%), Positives = 120/169 (71%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NV+H KSLP V RH D+D +I+RE TEGEYS+LEHESV GVVE LKIIT AKS RIA++
Sbjct: 144 NVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEY 203
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AF A + GRKKVTAVHKANIMKLGDGLFL+ C E+A YP+I FE MIVDN TMQ+VS
Sbjct: 204 AFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSR 263
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARH 509
P QFDVMV PNLYGNIV+N AVFE R+
Sbjct: 264 PQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRN 312
>U69268-1|AAB70115.1| 296|Homo sapiens NAD (H)-specific isocitrate
dehydrogenase gamma subunit protein.
Length = 296
Score = 211 bits (516), Expect = 1e-54
Identities = 106/169 (62%), Positives = 120/169 (71%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NV+H KSLP V RH D+D +I+RE TEGEYS+LEHESV GVVE LKIIT AKS RIA++
Sbjct: 60 NVIHWKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEY 119
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AF A + GRKKVTAVHKANIMKLGDGLFL+ C E+A YP+I FE MIVDN TMQ+VS
Sbjct: 120 AFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSR 179
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARH 509
P QFDVMV PNLYGNIV+N AVFE R+
Sbjct: 180 PQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRN 228
>BC001902-1|AAH01902.1| 393|Homo sapiens isocitrate dehydrogenase 3
(NAD+) gamma protein.
Length = 393
Score = 210 bits (512), Expect = 3e-54
Identities = 105/169 (62%), Positives = 119/169 (70%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NV+H KSLP V RH D+D +I+RE TEGEYS+LEHESV GVVE LKIIT AKS RIA++
Sbjct: 144 NVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEY 203
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AF A + GRKKVTAVHKANIMKLGDGLFL+ C E+A YP+I FE MIVDN TMQ+VS
Sbjct: 204 AFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSR 263
Query: 363 PNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARH 509
P Q DVMV PNLYGNIV+N AVFE R+
Sbjct: 264 PQQLDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRN 312
>AK001905-1|BAA91971.1| 233|Homo sapiens protein ( Homo sapiens
cDNA FLJ11043 fis, clone PLACE1004437, highly similar to
Human NAD+-specific isocitrate dehydrogenase beta
subunit ).
Length = 233
Score = 194 bits (472), Expect = 2e-49
Identities = 92/140 (65%), Positives = 105/140 (75%)
Frame = +3
Query: 111 ESVPGVVECLKIITAAKSERIAKFAFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEM 290
+S GV+ECLKI+T AKS+RIAKFAFDYA K GR KVTAVHKANIMKLGDGLFL+ CEE+
Sbjct: 25 QSARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEV 84
Query: 291 AKLYPRIQFEKMIVDNCTMQMVSNPNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXX 470
A+LYP+I+FE MIVDNC MQ+V NP QFDV+V PNLYGNI+DN
Sbjct: 85 AELYPKIKFETMIVDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESY 144
Query: 471 XXECAVFEQGARHIFSGAVG 530
E AVFE GARH F+ AVG
Sbjct: 145 SAEYAVFETGARHPFAQAVG 164
>U07681-1|AAA85639.1| 366|Homo sapiens NAD(H)-specific isocitrate
dehydrogenase alpha subunit precursor protein.
Length = 366
Score = 146 bits (354), Expect = 4e-35
Identities = 70/139 (50%), Positives = 96/139 (69%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NV S+ K + DV+ + IRE TEGEYS +EH V GVV+ +K+IT S+RIA+F
Sbjct: 123 NVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEF 182
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AF+YA R VTAVHKANIM++ DGLFL+ C E+A+ I+F +M +D + MV +
Sbjct: 183 AFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQD 242
Query: 363 PNQFDVMVTPNLYGNIVDN 419
P+QFDV+V PNLYG+I+ +
Sbjct: 243 PSQFDVLVMPNLYGDILSD 261
>BC021967-1|AAH21967.1| 366|Homo sapiens isocitrate dehydrogenase 3
(NAD+) alpha protein.
Length = 366
Score = 146 bits (354), Expect = 4e-35
Identities = 70/139 (50%), Positives = 96/139 (69%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NV S+ K + DV+ + IRE TEGEYS +EH V GVV+ +K+IT S+RIA+F
Sbjct: 123 NVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEF 182
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AF+YA R VTAVHKANIM++ DGLFL+ C E+A+ I+F +M +D + MV +
Sbjct: 183 AFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQD 242
Query: 363 PNQFDVMVTPNLYGNIVDN 419
P+QFDV+V PNLYG+I+ +
Sbjct: 243 PSQFDVLVMPNLYGDILSD 261
>AL442090-1|CAC09449.1| 288|Homo sapiens hypothetical protein
protein.
Length = 288
Score = 146 bits (354), Expect = 4e-35
Identities = 70/139 (50%), Positives = 96/139 (69%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NV S+ K + DV+ + IRE TEGEYS +EH V GVV+ +K+IT S+RIA+F
Sbjct: 45 NVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEF 104
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AF+YA R VTAVHKANIM++ DGLFL+ C E+A+ I+F +M +D + MV +
Sbjct: 105 AFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQD 164
Query: 363 PNQFDVMVTPNLYGNIVDN 419
P+QFDV+V PNLYG+I+ +
Sbjct: 165 PSQFDVLVMPNLYGDILSD 183
>AK222973-1|BAD96693.1| 366|Homo sapiens isocitrate dehydrogenase 3
(NAD+) alpha precursor variant protein.
Length = 366
Score = 146 bits (353), Expect = 6e-35
Identities = 70/139 (50%), Positives = 96/139 (69%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
NV S+ K + DV+ + IRE TEGEYS +EH V GVV+ +K+IT S+RIA+F
Sbjct: 123 NVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGVSKRIAEF 182
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSN 362
AF+YA R VTAVHKANIM++ DGLFL+ C E+A+ I+F +M +D + MV +
Sbjct: 183 AFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQD 242
Query: 363 PNQFDVMVTPNLYGNIVDN 419
P+QFDV+V PNLYG+I+ +
Sbjct: 243 PSQFDVLVMPNLYGDILSD 261
>U69269-1|AAB70116.1| 210|Homo sapiens NAD (H)-specific isocitrate
dehydrogenase gamma subunit protein.
Length = 210
Score = 135 bits (327), Expect = 8e-32
Identities = 69/117 (58%), Positives = 78/117 (66%)
Frame = +3
Query: 159 KSERIAKFAFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDN 338
KS RIA++AF A + GRKKVTAVHKANIMKLGDGLFL+ C E+A YP+I FE MIVDN
Sbjct: 1 KSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDN 60
Query: 339 CTMQMVSNPNQFDVMVTPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARH 509
TMQ+VS P QFDVMV PNLYGNIV+N AVFE R+
Sbjct: 61 TTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRN 117
>AK093338-1|BAC04136.1| 355|Homo sapiens protein ( Homo sapiens
cDNA FLJ36019 fis, clone TESTI2016421, highly similar to
PROTEIN KINASE C-BINDING PROTEIN NELL1. ).
Length = 355
Score = 125 bits (301), Expect = 1e-28
Identities = 60/93 (64%), Positives = 72/93 (77%)
Frame = +3
Query: 3 NVVHVKSLPNVKCRHHDVDCIIIREQTEGEYSALEHESVPGVVECLKIITAAKSERIAKF 182
+V+H+K+LPNV+ H DVD +++ E TEGEYS LEHESV GV E LKI+T AKS RIA++
Sbjct: 11 SVIHLKNLPNVETWHKDVDILVVWENTEGEYSNLEHESVKGVTESLKIMTKAKSLRIAEY 70
Query: 183 AFDYAVKMGRKKVTAVHKANIMKLGDGLFLRSC 281
AF A KMG KKV AVHK NI KLGDG FL+ C
Sbjct: 71 AFQLAQKMGCKKVMAVHKVNITKLGDGPFLQCC 103
>AF046929-1|AAF20164.1| 156|Homo sapiens NAD+-specific isocitrate
dehydrogenase b subunit protein.
Length = 156
Score = 104 bits (250), Expect = 2e-22
Identities = 48/87 (55%), Positives = 58/87 (66%)
Frame = +3
Query: 270 LRSCEEMAKLYPRIQFEKMIVDNCTMQMVSNPNQFDVMVTPNLYGNIVDNXXXXXXXXXX 449
L+ CEE+A+LYP+I+FE MI+DNC MQ+V NP QFDV+V PNLYGNI+DN
Sbjct: 1 LQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAG 60
Query: 450 XXXXXXXXXECAVFEQGARHIFSGAVG 530
E AVFE GARH F+ AVG
Sbjct: 61 VVPGESYSAEYAVFETGARHPFAQAVG 87
>AB209206-1|BAD92443.1| 174|Homo sapiens isocitrate dehydrogenase 3
(NAD+) gamma isoform b precursor variant protein.
Length = 174
Score = 95.9 bits (228), Expect = 8e-20
Identities = 49/101 (48%), Positives = 59/101 (58%)
Frame = +3
Query: 207 GRKKVTAVHKANIMKLGDGLFLRSCEEMAKLYPRIQFEKMIVDNCTMQMVSNPNQFDVMV 386
GR + + ++ KLGDGLFL+ C E+A YP+I FE MIVDN TMQ+VS P QFDVMV
Sbjct: 6 GRTQRASTAAWSMRKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMV 65
Query: 387 TPNLYGNIVDNXXXXXXXXXXXXXXXXXXXECAVFEQGARH 509
PNLYGNIV+N AVFE R+
Sbjct: 66 MPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRN 106
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,219,680
Number of Sequences: 237096
Number of extensions: 1529296
Number of successful extensions: 3747
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 3659
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3747
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 5160237082
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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