Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0002_L08
(656 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X63600-1|CAA45145.1| 629|Homo sapiens acid sphingomyelinase pro... 172 8e-43
M81780-2|AAA75009.1| 597|Homo sapiens acid sphingomyelinase pro... 172 8e-43
M81780-1|AAA75008.1| 629|Homo sapiens acid sphingomyelinase pro... 172 8e-43
BC041164-1|AAH41164.1| 364|Homo sapiens SMPD1 protein protein. 172 8e-43
AB209775-1|BAD93012.1| 664|Homo sapiens sphingomyelin phosphodi... 172 8e-43
M59916-1|AAA58377.1| 629|Homo sapiens acid sphingomyelinase pro... 171 2e-42
X59960-1|CAA42584.1| 627|Homo sapiens sphingomyelin phosphodies... 167 2e-41
X52678-1|CAA36901.1| 502|Homo sapiens acid sphingomyelinase (50... 165 2e-40
Y08134-1|CAA69328.1| 465|Homo sapiens acid sphingomyelinase-lik... 58 2e-08
BC014444-1|AAH14444.1| 373|Homo sapiens sphingomyelin phosphodi... 58 2e-08
AL512288-4|CAI14294.1| 373|Homo sapiens sphingomyelin phosphodi... 58 2e-08
AL512288-3|CAI14293.1| 455|Homo sapiens sphingomyelin phosphodi... 58 2e-08
AL512288-5|CAI14295.1| 269|Homo sapiens sphingomyelin phosphodi... 58 3e-08
X52679-1|CAA36902.1| 316|Homo sapiens acid sphingomyelinase (31... 50 1e-05
BC018999-1|AAH18999.1| 453|Homo sapiens sphingomyelin phosphodi... 42 0.001
AL732431-1|CAI23631.1| 453|Homo sapiens XXyac-YR36GH4.1 protein. 42 0.001
AL445198-5|CAI13083.1| 532|Homo sapiens nuclear factor I/A prot... 32 2.1
AL445198-4|CAI13079.1| 466|Homo sapiens nuclear factor I/A prot... 32 2.1
AL445198-3|CAI13081.1| 509|Homo sapiens nuclear factor I/A prot... 32 2.1
AL445198-2|CAI13082.1| 487|Homo sapiens nuclear factor I/A prot... 32 2.1
AL096888-6|CAI23242.1| 532|Homo sapiens nuclear factor I/A prot... 32 2.1
AL096888-5|CAI23239.1| 466|Homo sapiens nuclear factor I/A prot... 32 2.1
AL096888-4|CAI23240.1| 509|Homo sapiens nuclear factor I/A prot... 32 2.1
AL096888-3|CAI23237.1| 487|Homo sapiens nuclear factor I/A prot... 32 2.1
AL096888-2|CAI23238.1| 380|Homo sapiens nuclear factor I/A prot... 32 2.1
AB037860-1|BAA92677.1| 561|Homo sapiens KIAA1439 protein protein. 32 2.1
X61028-1|CAA43362.1| 124|Homo sapiens keratin K4 protein. 31 3.6
X07695-1|CAA30534.1| 408|Homo sapiens cytokeratin 4 (408 AA) pr... 31 3.6
BC042174-1|AAH42174.1| 534|Homo sapiens KRT4 protein protein. 31 3.6
BC032132-1|AAH32132.1| 118|Homo sapiens KRT4 protein protein. 31 3.6
BC022264-1|AAH22264.1| 498|Homo sapiens nuclear factor I/A prot... 31 3.6
BC003630-1|AAH03630.2| 324|Homo sapiens KRT4 protein protein. 31 3.6
AY043326-1|AAL14196.1| 534|Homo sapiens keratin 4 protein. 31 3.6
AL445198-1|CAI13080.1| 498|Homo sapiens nuclear factor I/A prot... 31 3.6
AL096888-1|CAI23241.1| 498|Homo sapiens nuclear factor I/A prot... 31 3.6
BC009860-1|AAH09860.2| 356|Homo sapiens TICAM1 protein protein. 30 8.3
AF070530-1|AAC28630.1| 416|Homo sapiens unknown protein. 30 8.3
AB097023-1|BAC77376.1| 712|Homo sapiens putative NFkB activatin... 30 8.3
AB093555-1|BAC44839.1| 712|Homo sapiens TIR domain containing a... 30 8.3
AB086380-1|BAC55579.1| 712|Homo sapiens TICAM-1 protein. 30 8.3
>X63600-1|CAA45145.1| 629|Homo sapiens acid sphingomyelinase
protein.
Length = 629
Score = 172 bits (419), Expect = 8e-43
Identities = 79/217 (36%), Positives = 115/217 (52%)
Frame = +1
Query: 4 INKMIYQFCVSLKIQSARVCEGITRLFGSEVVYVLKRITIGPDEICSFVIGDACGDVYNP 183
+ + + C LKI VC+ I LF ++V V +R + P E C ++G CG ++
Sbjct: 112 VGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGH-WDI 170
Query: 184 YHEWEVAFPPVPKPAVRPLDAPIDKAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRAS 363
+ W ++ P VPKP +P P AP ++L ++D H+D Y EG + DC +PLCCR
Sbjct: 171 FSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRG 230
Query: 364 SGPLRTPDSGAGRWGDYRKCDTPKRTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTK 543
SG GAG WG+Y KCD P RT++ +L + D + WTGD+P HDVW+QT+
Sbjct: 231 SGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPA-GPFDMVYWTGDIPAHDVWHQTR 289
Query: 544 EEHLQVFKKRLLKCLICFREYQFSQLSGNHESSPVNS 654
++ L+ GNHES+PVNS
Sbjct: 290 QDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNS 326
>M81780-2|AAA75009.1| 597|Homo sapiens acid sphingomyelinase
protein.
Length = 597
Score = 172 bits (419), Expect = 8e-43
Identities = 79/217 (36%), Positives = 115/217 (52%)
Frame = +1
Query: 4 INKMIYQFCVSLKIQSARVCEGITRLFGSEVVYVLKRITIGPDEICSFVIGDACGDVYNP 183
+ + + C LKI VC+ I LF ++V V +R + P E C ++G CG ++
Sbjct: 80 VGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGH-WDI 138
Query: 184 YHEWEVAFPPVPKPAVRPLDAPIDKAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRAS 363
+ W ++ P VPKP +P P AP ++L ++D H+D Y EG + DC +PLCCR
Sbjct: 139 FSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRG 198
Query: 364 SGPLRTPDSGAGRWGDYRKCDTPKRTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTK 543
SG GAG WG+Y KCD P RT++ +L + D + WTGD+P HDVW+QT+
Sbjct: 199 SGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPA-GPFDMVYWTGDIPAHDVWHQTR 257
Query: 544 EEHLQVFKKRLLKCLICFREYQFSQLSGNHESSPVNS 654
++ L+ GNHES+PVNS
Sbjct: 258 QDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNS 294
>M81780-1|AAA75008.1| 629|Homo sapiens acid sphingomyelinase
protein.
Length = 629
Score = 172 bits (419), Expect = 8e-43
Identities = 79/217 (36%), Positives = 115/217 (52%)
Frame = +1
Query: 4 INKMIYQFCVSLKIQSARVCEGITRLFGSEVVYVLKRITIGPDEICSFVIGDACGDVYNP 183
+ + + C LKI VC+ I LF ++V V +R + P E C ++G CG ++
Sbjct: 112 VGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGH-WDI 170
Query: 184 YHEWEVAFPPVPKPAVRPLDAPIDKAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRAS 363
+ W ++ P VPKP +P P AP ++L ++D H+D Y EG + DC +PLCCR
Sbjct: 171 FSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRG 230
Query: 364 SGPLRTPDSGAGRWGDYRKCDTPKRTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTK 543
SG GAG WG+Y KCD P RT++ +L + D + WTGD+P HDVW+QT+
Sbjct: 231 SGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPA-GPFDMVYWTGDIPAHDVWHQTR 289
Query: 544 EEHLQVFKKRLLKCLICFREYQFSQLSGNHESSPVNS 654
++ L+ GNHES+PVNS
Sbjct: 290 QDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNS 326
>BC041164-1|AAH41164.1| 364|Homo sapiens SMPD1 protein protein.
Length = 364
Score = 172 bits (419), Expect = 8e-43
Identities = 79/217 (36%), Positives = 115/217 (52%)
Frame = +1
Query: 4 INKMIYQFCVSLKIQSARVCEGITRLFGSEVVYVLKRITIGPDEICSFVIGDACGDVYNP 183
+ + + C LKI VC+ I LF ++V V +R + P E C ++G CG ++
Sbjct: 112 VGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGH-WDI 170
Query: 184 YHEWEVAFPPVPKPAVRPLDAPIDKAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRAS 363
+ W ++ P VPKP +P P AP ++L ++D H+D Y EG + DC +PLCCR
Sbjct: 171 FSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRG 230
Query: 364 SGPLRTPDSGAGRWGDYRKCDTPKRTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTK 543
SG GAG WG+Y KCD P RT++ +L + D + WTGD+P HDVW+QT+
Sbjct: 231 SGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPA-GPFDMVYWTGDIPAHDVWHQTR 289
Query: 544 EEHLQVFKKRLLKCLICFREYQFSQLSGNHESSPVNS 654
++ L+ GNHES+PVNS
Sbjct: 290 QDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNS 326
>AB209775-1|BAD93012.1| 664|Homo sapiens sphingomyelin
phosphodiesterase 1, acid lysosomal isoform 1 precursor
variant protein.
Length = 664
Score = 172 bits (419), Expect = 8e-43
Identities = 79/217 (36%), Positives = 115/217 (52%)
Frame = +1
Query: 4 INKMIYQFCVSLKIQSARVCEGITRLFGSEVVYVLKRITIGPDEICSFVIGDACGDVYNP 183
+ + + C LKI VC+ I LF ++V V +R + P E C ++G CG ++
Sbjct: 147 VGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGH-WDI 205
Query: 184 YHEWEVAFPPVPKPAVRPLDAPIDKAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRAS 363
+ W ++ P VPKP +P P AP ++L ++D H+D Y EG + DC +PLCCR
Sbjct: 206 FSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRG 265
Query: 364 SGPLRTPDSGAGRWGDYRKCDTPKRTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTK 543
SG GAG WG+Y KCD P RT++ +L + D + WTGD+P HDVW+QT+
Sbjct: 266 SGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPA-GPFDMVYWTGDIPAHDVWHQTR 324
Query: 544 EEHLQVFKKRLLKCLICFREYQFSQLSGNHESSPVNS 654
++ L+ GNHES+PVNS
Sbjct: 325 QDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNS 361
>M59916-1|AAA58377.1| 629|Homo sapiens acid sphingomyelinase
protein.
Length = 629
Score = 171 bits (416), Expect = 2e-42
Identities = 79/217 (36%), Positives = 114/217 (52%)
Frame = +1
Query: 4 INKMIYQFCVSLKIQSARVCEGITRLFGSEVVYVLKRITIGPDEICSFVIGDACGDVYNP 183
+ + + C LKI VC+ I LF ++V V +R + P E C ++G CG ++
Sbjct: 112 VGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGH-WDI 170
Query: 184 YHEWEVAFPPVPKPAVRPLDAPIDKAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRAS 363
+ W ++ P VPKP +P P AP ++L ++D H+D Y EG + DC +PLCCR
Sbjct: 171 FSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRG 230
Query: 364 SGPLRTPDSGAGRWGDYRKCDTPKRTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTK 543
SG GAG WG+Y KCD P RT++ +L + D + WTGD+P HDVW+QT+
Sbjct: 231 SGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPA-GPFDMVYWTGDIPAHDVWHQTR 289
Query: 544 EEHLQVFKKRLLKCLICFREYQFSQLSGNHESSPVNS 654
++ L+ GNHES PVNS
Sbjct: 290 QDQLRALTTVTALVRKFLGPVPVYPAVGNHESIPVNS 326
>X59960-1|CAA42584.1| 627|Homo sapiens sphingomyelin
phosphodiesterase protein.
Length = 627
Score = 167 bits (407), Expect = 2e-41
Identities = 78/217 (35%), Positives = 114/217 (52%)
Frame = +1
Query: 4 INKMIYQFCVSLKIQSARVCEGITRLFGSEVVYVLKRITIGPDEICSFVIGDACGDVYNP 183
+ + + C LKI VC+ I LF ++V V +R + P E ++G CG ++
Sbjct: 110 VGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEARGLLLGSTCGH-WDI 168
Query: 184 YHEWEVAFPPVPKPAVRPLDAPIDKAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRAS 363
+ W ++ P VPKP +P P AP ++L ++D H+D Y EG + DC +PLCCR
Sbjct: 169 FSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRG 228
Query: 364 SGPLRTPDSGAGRWGDYRKCDTPKRTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTK 543
SG GAG WG+Y KCD P RT++ +L + D + WTGD+P HDVW+QT+
Sbjct: 229 SGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPA-GPFDMVYWTGDIPAHDVWHQTR 287
Query: 544 EEHLQVFKKRLLKCLICFREYQFSQLSGNHESSPVNS 654
++ L+ GNHES+PVNS
Sbjct: 288 QDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNS 324
>X52678-1|CAA36901.1| 502|Homo sapiens acid sphingomyelinase (502
AA) protein.
Length = 502
Score = 165 bits (400), Expect = 2e-40
Identities = 75/199 (37%), Positives = 107/199 (53%)
Frame = +1
Query: 58 VCEGITRLFGSEVVYVLKRITIGPDEICSFVIGDACGDVYNPYHEWEVAFPPVPKPAVRP 237
VC+ I LF ++V V +R + P E C ++G CG ++ + W ++ P VPKP +P
Sbjct: 3 VCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGH-WDIFSSWNISLPTVPKPPPKP 61
Query: 238 LDAPIDKAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRASSGPLRTPDSGAGRWGDYR 417
P AP ++L ++D H+D Y EG + DC +PLCCR SG GAG WG+Y
Sbjct: 62 PSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRGSGLPPASRPGAGYWGEYS 121
Query: 418 KCDTPKRTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTKEEHLQVFKKRLLKCLICF 597
KCD P RT++ +L + D + WTGD+P HDVW+QT+++ L+
Sbjct: 122 KCDLPLRTLESLLSGLGPA-GPFDMVYWTGDIPAHDVWHQTRQDQLRALTTVTALVRKFL 180
Query: 598 REYQFSQLSGNHESSPVNS 654
GNHES PVNS
Sbjct: 181 GPVPVYPAVGNHESIPVNS 199
>Y08134-1|CAA69328.1| 465|Homo sapiens acid sphingomyelinase-like
phosphodiesterase protein.
Length = 465
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 1/133 (0%)
Frame = +1
Query: 256 KAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRASSGPLRTPDSGAGRWGDYRKCDTPK 435
+A K I+D H DP Y +P S+G PD AG WGDY CD+P
Sbjct: 17 RAEPGKFWHIADLHLDPDYKVS-----KDPFQVCPSAGSQPVPD--AGPWGDYL-CDSPW 68
Query: 436 RTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTKEEHLQVFKKRLLKCL-ICFREYQF 612
I+ + + + + D+ILWTGD PH + E + +RL K + F + +
Sbjct: 69 ALINSSIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKV 128
Query: 613 SQLSGNHESSPVN 651
GNH+ P N
Sbjct: 129 YAALGNHDFHPKN 141
>BC014444-1|AAH14444.1| 373|Homo sapiens sphingomyelin
phosphodiesterase, acid-like 3B protein.
Length = 373
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 1/133 (0%)
Frame = +1
Query: 256 KAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRASSGPLRTPDSGAGRWGDYRKCDTPK 435
+A K I+D H DP Y +P S+G PD AG WGDY CD+P
Sbjct: 17 RAEPGKFWHIADLHLDPDYKVS-----KDPFQVCPSAGSQPVPD--AGPWGDYL-CDSPW 68
Query: 436 RTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTKEEHLQVFKKRLLKCL-ICFREYQF 612
I+ + + + + D+ILWTGD PH + E + +RL K + F + +
Sbjct: 69 ALINSSIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKV 128
Query: 613 SQLSGNHESSPVN 651
GNH+ P N
Sbjct: 129 YAALGNHDFHPKN 141
>AL512288-4|CAI14294.1| 373|Homo sapiens sphingomyelin
phosphodiesterase, acid-like 3B protein.
Length = 373
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 1/133 (0%)
Frame = +1
Query: 256 KAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRASSGPLRTPDSGAGRWGDYRKCDTPK 435
+A K I+D H DP Y +P S+G PD AG WGDY CD+P
Sbjct: 17 RAEPGKFWHIADLHLDPDYKVS-----KDPFQVCPSAGSQPVPD--AGPWGDYL-CDSPW 68
Query: 436 RTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTKEEHLQVFKKRLLKCL-ICFREYQF 612
I+ + + + + D+ILWTGD PH + E + +RL K + F + +
Sbjct: 69 ALINSSIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKV 128
Query: 613 SQLSGNHESSPVN 651
GNH+ P N
Sbjct: 129 YAALGNHDFHPKN 141
>AL512288-3|CAI14293.1| 455|Homo sapiens sphingomyelin
phosphodiesterase, acid-like 3B protein.
Length = 455
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/133 (31%), Positives = 60/133 (45%), Gaps = 1/133 (0%)
Frame = +1
Query: 256 KAPTFKVLQISDTHFDPYYAEGANADCNEPLCCRASSGPLRTPDSGAGRWGDYRKCDTPK 435
+A K I+D H DP Y +P S+G PD AG WGDY CD+P
Sbjct: 17 RAEPGKFWHIADLHLDPDYKVS-----KDPFQVCPSAGSQPVPD--AGPWGDYL-CDSPW 68
Query: 436 RTIDHMLKHIADTHTDIDYILWTGDLPPHDVWNQTKEEHLQVFKKRLLKCL-ICFREYQF 612
I+ + + + + D+ILWTGD PH + E + +RL K + F + +
Sbjct: 69 ALINSSIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKV 128
Query: 613 SQLSGNHESSPVN 651
GNH+ P N
Sbjct: 129 YAALGNHDFHPKN 141
>AL512288-5|CAI14295.1| 269|Homo sapiens sphingomyelin
phosphodiesterase, acid-like 3B protein.
Length = 269
Score = 58.0 bits (134), Expect = 3e-08
Identities = 41/128 (32%), Positives = 58/128 (45%), Gaps = 1/128 (0%)
Frame = +1
Query: 271 KVLQISDTHFDPYYAEGANADCNEPLCCRASSGPLRTPDSGAGRWGDYRKCDTPKRTIDH 450
K I+D H DP Y +P S+G PD AG WGDY CD+P I+
Sbjct: 52 KFWHIADLHLDPDYKVS-----KDPFQVCPSAGSQPVPD--AGPWGDYL-CDSPWALINS 103
Query: 451 MLKHIADTHTDIDYILWTGDLPPHDVWNQTKEEHLQVFKKRLLKCL-ICFREYQFSQLSG 627
+ + + + D+ILWTGD PH + E + +RL K + F + + G
Sbjct: 104 SIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKVYAALG 163
Query: 628 NHESSPVN 651
NH+ P N
Sbjct: 164 NHDFHPKN 171
>X52679-1|CAA36902.1| 316|Homo sapiens acid sphingomyelinase (317
AA) protein.
Length = 316
Score = 49.6 bits (113), Expect = 1e-05
Identities = 22/56 (39%), Positives = 29/56 (51%)
Frame = +1
Query: 487 DYILWTGDLPPHDVWNQTKEEHLQVFKKRLLKCLICFREYQFSQLSGNHESSPVNS 654
D + WTGD+P HDVW+QT+++ L+ GNHES PVNS
Sbjct: 2 DMVYWTGDIPAHDVWHQTRQDQLRALTTVTALVRKFLGPVPVYPAVGNHESIPVNS 57
>BC018999-1|AAH18999.1| 453|Homo sapiens sphingomyelin
phosphodiesterase, acid-like 3A protein.
Length = 453
Score = 42.3 bits (95), Expect = 0.001
Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 1/122 (0%)
Frame = +1
Query: 283 ISDTHFDPYYAEGANADCNEPLCCRASSGPLRTPDSGAGRWGDYRKCDTPKRTIDHMLKH 462
++D H DP Y + + C +S G S G +GD CD+P + I
Sbjct: 43 VTDLHLDPTY----HITDDHTKVCASSKG---ANASNPGPFGDVL-CDSPYQLILSAFDF 94
Query: 463 IADTHTDIDYILWTGDLPPH-DVWNQTKEEHLQVFKKRLLKCLICFREYQFSQLSGNHES 639
I ++ + +++WTGD PPH V + + + V F Q GNH+
Sbjct: 95 IKNSGQEASFMIWTGDSPPHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDY 154
Query: 640 SP 645
P
Sbjct: 155 WP 156
>AL732431-1|CAI23631.1| 453|Homo sapiens XXyac-YR36GH4.1 protein.
Length = 453
Score = 42.3 bits (95), Expect = 0.001
Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 1/122 (0%)
Frame = +1
Query: 283 ISDTHFDPYYAEGANADCNEPLCCRASSGPLRTPDSGAGRWGDYRKCDTPKRTIDHMLKH 462
++D H DP Y + + C +S G S G +GD CD+P + I
Sbjct: 43 VTDLHLDPTY----HITDDHTKVCASSKG---ANASNPGPFGDVL-CDSPYQLILSAFDF 94
Query: 463 IADTHTDIDYILWTGDLPPH-DVWNQTKEEHLQVFKKRLLKCLICFREYQFSQLSGNHES 639
I ++ + +++WTGD PPH V + + + V F Q GNH+
Sbjct: 95 IKNSGQEASFMIWTGDSPPHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDY 154
Query: 640 SP 645
P
Sbjct: 155 WP 156
>AL445198-5|CAI13083.1| 532|Homo sapiens nuclear factor I/A
protein.
Length = 532
Score = 31.9 bits (69), Expect = 2.1
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPTFKVLQISDTHFDPYYAEGAN 327
G + G V+NP+ + PP P P RP+ P+ K PT + + P Y+ +
Sbjct: 444 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 503
Query: 328 ADCN 339
+ N
Sbjct: 504 SPAN 507
>AL445198-4|CAI13079.1| 466|Homo sapiens nuclear factor I/A
protein.
Length = 466
Score = 31.9 bits (69), Expect = 2.1
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPTFKVLQISDTHFDPYYAEGAN 327
G + G V+NP+ + PP P P RP+ P+ K PT + + P Y+ +
Sbjct: 378 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 437
Query: 328 ADCN 339
+ N
Sbjct: 438 SPAN 441
>AL445198-3|CAI13081.1| 509|Homo sapiens nuclear factor I/A
protein.
Length = 509
Score = 31.9 bits (69), Expect = 2.1
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPTFKVLQISDTHFDPYYAEGAN 327
G + G V+NP+ + PP P P RP+ P+ K PT + + P Y+ +
Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 480
Query: 328 ADCN 339
+ N
Sbjct: 481 SPAN 484
>AL445198-2|CAI13082.1| 487|Homo sapiens nuclear factor I/A
protein.
Length = 487
Score = 31.9 bits (69), Expect = 2.1
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPTFKVLQISDTHFDPYYAEGAN 327
G + G V+NP+ + PP P P RP+ P+ K PT + + P Y+ +
Sbjct: 399 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 458
Query: 328 ADCN 339
+ N
Sbjct: 459 SPAN 462
>AL096888-6|CAI23242.1| 532|Homo sapiens nuclear factor I/A
protein.
Length = 532
Score = 31.9 bits (69), Expect = 2.1
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPTFKVLQISDTHFDPYYAEGAN 327
G + G V+NP+ + PP P P RP+ P+ K PT + + P Y+ +
Sbjct: 444 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 503
Query: 328 ADCN 339
+ N
Sbjct: 504 SPAN 507
>AL096888-5|CAI23239.1| 466|Homo sapiens nuclear factor I/A
protein.
Length = 466
Score = 31.9 bits (69), Expect = 2.1
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPTFKVLQISDTHFDPYYAEGAN 327
G + G V+NP+ + PP P P RP+ P+ K PT + + P Y+ +
Sbjct: 378 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 437
Query: 328 ADCN 339
+ N
Sbjct: 438 SPAN 441
>AL096888-4|CAI23240.1| 509|Homo sapiens nuclear factor I/A
protein.
Length = 509
Score = 31.9 bits (69), Expect = 2.1
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPTFKVLQISDTHFDPYYAEGAN 327
G + G V+NP+ + PP P P RP+ P+ K PT + + P Y+ +
Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 480
Query: 328 ADCN 339
+ N
Sbjct: 481 SPAN 484
>AL096888-3|CAI23237.1| 487|Homo sapiens nuclear factor I/A
protein.
Length = 487
Score = 31.9 bits (69), Expect = 2.1
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPTFKVLQISDTHFDPYYAEGAN 327
G + G V+NP+ + PP P P RP+ P+ K PT + + P Y+ +
Sbjct: 399 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 458
Query: 328 ADCN 339
+ N
Sbjct: 459 SPAN 462
>AL096888-2|CAI23238.1| 380|Homo sapiens nuclear factor I/A
protein.
Length = 380
Score = 31.9 bits (69), Expect = 2.1
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPTFKVLQISDTHFDPYYAEGAN 327
G + G V+NP+ + PP P P RP+ P+ K PT + + P Y+ +
Sbjct: 292 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 351
Query: 328 ADCN 339
+ N
Sbjct: 352 SPAN 355
>AB037860-1|BAA92677.1| 561|Homo sapiens KIAA1439 protein protein.
Length = 561
Score = 31.9 bits (69), Expect = 2.1
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPTFKVLQISDTHFDPYYAEGAN 327
G + G V+NP+ + PP P P RP+ P+ K PT + + P Y+ +
Sbjct: 473 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 532
Query: 328 ADCN 339
+ N
Sbjct: 533 SPAN 536
>X61028-1|CAA43362.1| 124|Homo sapiens keratin K4 protein.
Length = 124
Score = 31.1 bits (67), Expect = 3.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
Frame = -1
Query: 362 EALQQSGSLQSAFAPSA*YGSKCVSEICKTLNVGA---LSIGASKGRTAGFGTGGNATSH 192
E + SG QSA + S GS I L G+ LS G G +GFG GG+ +
Sbjct: 50 EEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGS 109
Query: 191 S 189
S
Sbjct: 110 S 110
>X07695-1|CAA30534.1| 408|Homo sapiens cytokeratin 4 (408 AA)
protein.
Length = 408
Score = 31.1 bits (67), Expect = 3.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
Frame = -1
Query: 362 EALQQSGSLQSAFAPSA*YGSKCVSEICKTLNVGA---LSIGASKGRTAGFGTGGNATSH 192
E + SG QSA + S GS I L G+ LS G G +GFG GG+ +
Sbjct: 334 EEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGS 393
Query: 191 S 189
S
Sbjct: 394 S 394
>BC042174-1|AAH42174.1| 534|Homo sapiens KRT4 protein protein.
Length = 534
Score = 31.1 bits (67), Expect = 3.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
Frame = -1
Query: 362 EALQQSGSLQSAFAPSA*YGSKCVSEICKTLNVGA---LSIGASKGRTAGFGTGGNATSH 192
E + SG QSA + S GS I L G+ LS G G +GFG GG+ +
Sbjct: 460 EEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGS 519
Query: 191 S 189
S
Sbjct: 520 S 520
>BC032132-1|AAH32132.1| 118|Homo sapiens KRT4 protein protein.
Length = 118
Score = 31.1 bits (67), Expect = 3.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
Frame = -1
Query: 362 EALQQSGSLQSAFAPSA*YGSKCVSEICKTLNVGA---LSIGASKGRTAGFGTGGNATSH 192
E + SG QSA + S GS I L G+ LS G G +GFG GG+ +
Sbjct: 44 EEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGS 103
Query: 191 S 189
S
Sbjct: 104 S 104
>BC022264-1|AAH22264.1| 498|Homo sapiens nuclear factor I/A
protein.
Length = 498
Score = 31.1 bits (67), Expect = 3.6
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPT 267
G + G V+NP+ + PP P P RP+ P+ K PT
Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPT 460
>BC003630-1|AAH03630.2| 324|Homo sapiens KRT4 protein protein.
Length = 324
Score = 31.1 bits (67), Expect = 3.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
Frame = -1
Query: 362 EALQQSGSLQSAFAPSA*YGSKCVSEICKTLNVGA---LSIGASKGRTAGFGTGGNATSH 192
E + SG QSA + S GS I L G+ LS G G +GFG GG+ +
Sbjct: 250 EEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGS 309
Query: 191 S 189
S
Sbjct: 310 S 310
>AY043326-1|AAL14196.1| 534|Homo sapiens keratin 4 protein.
Length = 534
Score = 31.1 bits (67), Expect = 3.6
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 3/61 (4%)
Frame = -1
Query: 362 EALQQSGSLQSAFAPSA*YGSKCVSEICKTLNVGA---LSIGASKGRTAGFGTGGNATSH 192
E + SG QSA + S GS I L G+ LS G G +GFG GG+ +
Sbjct: 460 EEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGS 519
Query: 191 S 189
S
Sbjct: 520 S 520
>AL445198-1|CAI13080.1| 498|Homo sapiens nuclear factor I/A
protein.
Length = 498
Score = 31.1 bits (67), Expect = 3.6
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPT 267
G + G V+NP+ + PP P P RP+ P+ K PT
Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPT 460
>AL096888-1|CAI23241.1| 498|Homo sapiens nuclear factor I/A
protein.
Length = 498
Score = 31.1 bits (67), Expect = 3.6
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%)
Frame = +1
Query: 154 GDACGDVYNPYHEWEVAFPPVPKPAVRPLDAPI--DKAPT 267
G + G V+NP+ + PP P P RP+ P+ K PT
Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPT 460
>BC009860-1|AAH09860.2| 356|Homo sapiens TICAM1 protein protein.
Length = 356
Score = 29.9 bits (64), Expect = 8.3
Identities = 12/32 (37%), Positives = 16/32 (50%), Gaps = 2/32 (6%)
Frame = +1
Query: 181 PYHEWEVAFPPVP--KPAVRPLDAPIDKAPTF 270
P H W+ PP P +PA P P ++P F
Sbjct: 276 PLHAWQAGTPPPPSPQPAAFPQSLPFPQSPAF 307
>AF070530-1|AAC28630.1| 416|Homo sapiens unknown protein.
Length = 416
Score = 29.9 bits (64), Expect = 8.3
Identities = 12/32 (37%), Positives = 16/32 (50%), Gaps = 2/32 (6%)
Frame = +1
Query: 181 PYHEWEVAFPPVP--KPAVRPLDAPIDKAPTF 270
P H W+ PP P +PA P P ++P F
Sbjct: 336 PLHAWQAGTPPPPSPQPAAFPQSLPFPQSPAF 367
>AB097023-1|BAC77376.1| 712|Homo sapiens putative NFkB activating
protein protein.
Length = 712
Score = 29.9 bits (64), Expect = 8.3
Identities = 12/32 (37%), Positives = 16/32 (50%), Gaps = 2/32 (6%)
Frame = +1
Query: 181 PYHEWEVAFPPVP--KPAVRPLDAPIDKAPTF 270
P H W+ PP P +PA P P ++P F
Sbjct: 632 PLHAWQAGTPPPPSPQPAAFPQSLPFPQSPAF 663
>AB093555-1|BAC44839.1| 712|Homo sapiens TIR domain containing
adaptor inducing interferon-beta protein.
Length = 712
Score = 29.9 bits (64), Expect = 8.3
Identities = 12/32 (37%), Positives = 16/32 (50%), Gaps = 2/32 (6%)
Frame = +1
Query: 181 PYHEWEVAFPPVP--KPAVRPLDAPIDKAPTF 270
P H W+ PP P +PA P P ++P F
Sbjct: 632 PLHAWQAGTPPPPSPQPAAFPQSLPFPQSPAF 663
>AB086380-1|BAC55579.1| 712|Homo sapiens TICAM-1 protein.
Length = 712
Score = 29.9 bits (64), Expect = 8.3
Identities = 12/32 (37%), Positives = 16/32 (50%), Gaps = 2/32 (6%)
Frame = +1
Query: 181 PYHEWEVAFPPVP--KPAVRPLDAPIDKAPTF 270
P H W+ PP P +PA P P ++P F
Sbjct: 632 PLHAWQAGTPPPPSPQPAAFPQSLPFPQSPAF 663
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,164,384
Number of Sequences: 237096
Number of extensions: 2411669
Number of successful extensions: 5730
Number of sequences better than 10.0: 40
Number of HSP's better than 10.0 without gapping: 5395
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5674
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7366354010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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