Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0002_A04
(443 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9V9X4 Cluster: CG11334-PA, isoform A; n=14; Eukaryota|... 138 5e-32
UniRef50_Q4FZP2 Cluster: MGC116493 protein; n=7; Coelomata|Rep: ... 83 2e-15
UniRef50_Q9AYT7 Cluster: IDI2; n=25; Eukaryota|Rep: IDI2 - Horde... 73 4e-12
UniRef50_A1CY38 Cluster: Translation initiation factor, putative... 73 4e-12
UniRef50_Q0UX53 Cluster: Putative uncharacterized protein; n=1; ... 72 6e-12
UniRef50_Q93169 Cluster: Uncharacterized protein C01G10.9; n=2; ... 70 3e-11
UniRef50_Q5AD59 Cluster: Potential Initiation factor 2 subunit f... 69 3e-11
UniRef50_A7EGZ3 Cluster: Putative uncharacterized protein; n=2; ... 66 4e-10
UniRef50_Q06489 Cluster: Methylthioribose-1-phosphate isomerase;... 61 9e-09
UniRef50_UPI00006CFF79 Cluster: 5-methylthioribose kinase family... 58 1e-07
UniRef50_Q67MP0 Cluster: Translation initiation factor eIF-2B al... 57 2e-07
UniRef50_Q4Q0R9 Cluster: Translation initiation factor 2 subunit... 57 2e-07
UniRef50_A6C0G9 Cluster: Putative translation initiation factor,... 50 2e-05
UniRef50_Q8F2A8 Cluster: Probable methylthioribose-1-phosphate i... 48 7e-05
UniRef50_O31662 Cluster: Methylthioribose-1-phosphate isomerase;... 48 9e-05
UniRef50_O29877 Cluster: Putative translation initiation factor ... 48 1e-04
UniRef50_A3DN77 Cluster: EIF-2B alpha/beta/delta-related unchara... 42 0.005
UniRef50_A1RWS6 Cluster: EIF-2B alpha/beta/delta-related unchara... 41 0.010
UniRef50_Q4JB92 Cluster: Translation initiation factor eIF-2B al... 40 0.018
UniRef50_A5UQK6 Cluster: Putative translation initiation factor,... 40 0.024
UniRef50_A0LIZ1 Cluster: EIF-2B alpha/beta/delta-related unchara... 38 0.074
UniRef50_O58433 Cluster: Putative translation initiation factor ... 38 0.097
UniRef50_A1SDR1 Cluster: EIF-2B alpha/beta/delta-related unchara... 38 0.13
UniRef50_Q0LDK7 Cluster: Putative translation initiation factor,... 37 0.17
UniRef50_Q55N23 Cluster: Putative uncharacterized protein; n=2; ... 37 0.17
UniRef50_Q5H060 Cluster: Initiation factor eIF-2B; n=7; Gammapro... 37 0.22
UniRef50_Q9HZ65 Cluster: Probable methylthioribose-1-phosphate i... 36 0.30
UniRef50_Q2LXN1 Cluster: Methylthioribose salvage protein; n=6; ... 36 0.39
UniRef50_Q2IH96 Cluster: Initiation factor 2B alpha/beta/delta; ... 36 0.39
UniRef50_Q1N0Y8 Cluster: Translation initiation factor IF-2B sub... 36 0.52
UniRef50_Q1FHK8 Cluster: Binding-protein-dependent transport sys... 36 0.52
UniRef50_Q8R7Q1 Cluster: Sugar permeases; n=4; Bacteria|Rep: Sug... 34 1.6
UniRef50_Q8DK09 Cluster: Translation initiation factor IF-2B alp... 33 2.1
UniRef50_Q54R90 Cluster: Translation initiation factor eIF-2B al... 33 2.1
UniRef50_A4W7Z1 Cluster: EIF-2B alpha/beta/delta-related unchara... 33 2.8
UniRef50_Q5CXZ3 Cluster: Glycoprotein, putative; n=2; Cryptospor... 33 2.8
UniRef50_A1S110 Cluster: Glycosyl transferase, family 2; n=1; Th... 33 2.8
UniRef50_Q2RRC9 Cluster: Sensor protein; n=1; Rhodospirillum rub... 33 3.7
UniRef50_P74497 Cluster: Probable methylthioribose-1-phosphate i... 32 4.8
UniRef50_Q2FN46 Cluster: Putative translation initiation factor,... 32 6.4
UniRef50_O57947 Cluster: Putative translation initiation factor ... 32 6.4
UniRef50_UPI0000F1E8D9 Cluster: PREDICTED: hypothetical protein;... 31 8.5
UniRef50_Q9RXY2 Cluster: Putative uncharacterized protein; n=1; ... 31 8.5
UniRef50_Q8TWU6 Cluster: Predicted RNA-binding protein, contains... 31 8.5
UniRef50_Q9YE84 Cluster: Putative translation initiation factor ... 31 8.5
>UniRef50_Q9V9X4 Cluster: CG11334-PA, isoform A; n=14;
Eukaryota|Rep: CG11334-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 364
Score = 138 bits (334), Expect = 5e-32
Identities = 69/123 (56%), Positives = 85/123 (69%)
Frame = +3
Query: 75 MSLESIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLA 254
MSL+SIKY RGS Q++YV V+GVEDGW+VINKMQVRGAPAIAIVGCLSLA
Sbjct: 1 MSLQSIKYSRGSLEILDQLLLPGQSKYVVVRGVEDGWKVINKMQVRGAPAIAIVGCLSLA 60
Query: 255 IELLKDNIADKKIMRQEIEGKLNYLVSARPTAVNIKXXXXXXXXXXXXXCADDSVSHEEF 434
+E+ ++ +KK +RQEIEGKLNYLVSARPTAVN+K D+++ +
Sbjct: 61 VEINPEDFENKKSLRQEIEGKLNYLVSARPTAVNMKIAADELITLANELYKDEAIDVTQM 120
Query: 435 KER 443
K R
Sbjct: 121 KHR 123
>UniRef50_Q4FZP2 Cluster: MGC116493 protein; n=7; Coelomata|Rep:
MGC116493 protein - Xenopus laevis (African clawed frog)
Length = 354
Score = 83.4 bits (197), Expect = 2e-15
Identities = 46/96 (47%), Positives = 58/96 (60%)
Frame = +3
Query: 75 MSLESIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLA 254
MSLES++Y RGS ++ Y V GV+ G I M+VRGAPAIAIVG LSLA
Sbjct: 1 MSLESVRYSRGSLQVLNQLLLPHKSEYEPVTGVQQGADAIRTMKVRGAPAIAIVGVLSLA 60
Query: 255 IELLKDNIADKKIMRQEIEGKLNYLVSARPTAVNIK 362
+EL D + + L++LVSARPTAVN+K
Sbjct: 61 VELTTKPCQDVPSLITFVRESLHHLVSARPTAVNMK 96
>UniRef50_Q9AYT7 Cluster: IDI2; n=25; Eukaryota|Rep: IDI2 - Hordeum
vulgare (Barley)
Length = 367
Score = 72.5 bits (170), Expect = 4e-12
Identities = 42/95 (44%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Frame = +3
Query: 78 SLESIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAI 257
+L+SI Y RG+ + YV V+ DGW I M VRGAPAIAI LSLA+
Sbjct: 6 ALQSILYGRGALRLLDQRKLPLEEVYVDVKDSADGWNAIRDMVVRGAPAIAIAAALSLAV 65
Query: 258 ELLKDN-IADKKIMRQEIEGKLNYLVSARPTAVNI 359
E+ N I + KL YLVS+RPTAVN+
Sbjct: 66 EVNDHNFIGTPAEAASFVSKKLEYLVSSRPTAVNL 100
>UniRef50_A1CY38 Cluster: Translation initiation factor, putative;
n=11; Fungi/Metazoa group|Rep: Translation initiation
factor, putative - Neosartorya fischeri (strain ATCC
1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus
(strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 387
Score = 72.5 bits (170), Expect = 4e-12
Identities = 42/98 (42%), Positives = 56/98 (57%), Gaps = 5/98 (5%)
Frame = +3
Query: 81 LESIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIE 260
L++I+Y RG +++ +Q ED W I +M+VRGAPAIAIV L+LA E
Sbjct: 5 LQAIRYSRGKLAIIDQLQLPYVEKFITIQTPEDAWHAIKEMRVRGAPAIAIVAALALASE 64
Query: 261 LLKDNIADKKIMRQE-----IEGKLNYLVSARPTAVNI 359
L + DK E I KL+YLVS+RPTAVN+
Sbjct: 65 LNTLIVHDKLSSGAEEVKLFIREKLDYLVSSRPTAVNL 102
>UniRef50_Q0UX53 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 355
Score = 71.7 bits (168), Expect = 6e-12
Identities = 43/123 (34%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = +3
Query: 75 MSLESIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLA 254
M L++IKY RG Y + D W I +M+ RGAPAIAIV LSLA
Sbjct: 1 MVLQAIKYTRGQLEILDQLKLPHAEEYDHIYSSTDAWHAIKEMRTRGAPAIAIVAALSLA 60
Query: 255 IELLKDNIAD-KKIMRQEIEGKLNYLVSARPTAVNIKXXXXXXXXXXXXXCADDSVSHEE 431
+EL ++ + ++ I KL YLV++RPTAVN+ A + S E
Sbjct: 61 VELTNMKLSSIAEEVQVFITEKLEYLVTSRPTAVNLADAAGKLKKITDEAAAREGTSGES 120
Query: 432 FKE 440
+E
Sbjct: 121 VRE 123
>UniRef50_Q93169 Cluster: Uncharacterized protein C01G10.9; n=2;
Caenorhabditis|Rep: Uncharacterized protein C01G10.9 -
Caenorhabditis elegans
Length = 366
Score = 69.7 bits (163), Expect = 3e-11
Identities = 36/94 (38%), Positives = 58/94 (61%)
Frame = +3
Query: 81 LESIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIE 260
L+S+K+ + + +Y+ V+GV D + VI MQVRGAP IA+VG L L +E
Sbjct: 25 LDSLKFDGTNLEVLDQLLLPHEFKYIPVEGVSDAFAVIKSMQVRGAPLIAVVGSLGLLLE 84
Query: 261 LLKDNIADKKIMRQEIEGKLNYLVSARPTAVNIK 362
+ K + D + + Q K+N+L+S+RPTAV+++
Sbjct: 85 IQKASELDSESIIQ----KINFLISSRPTAVDLR 114
>UniRef50_Q5AD59 Cluster: Potential Initiation factor 2 subunit
family protein; n=5; Saccharomycetales|Rep: Potential
Initiation factor 2 subunit family protein - Candida
albicans (Yeast)
Length = 416
Score = 69.3 bits (162), Expect = 3e-11
Identities = 33/74 (44%), Positives = 52/74 (70%), Gaps = 3/74 (4%)
Frame = +3
Query: 147 TRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIEL---LKDNIADKKIMRQEIEGK 317
T Y+ + +ED ++ I MQVRGAPAIAIVG S+ +E+ LK + +++K ++ +
Sbjct: 32 TSYIPINNIEDAFKAIKLMQVRGAPAIAIVGAFSVVVEVSNYLKQSDSNQKTIK-NLNDS 90
Query: 318 LNYLVSARPTAVNI 359
LNYL+++RPTAVN+
Sbjct: 91 LNYLITSRPTAVNL 104
>UniRef50_A7EGZ3 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Sclerotinia sclerotiorum 1980
Length = 445
Score = 65.7 bits (153), Expect = 4e-10
Identities = 40/95 (42%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Frame = +3
Query: 81 LESIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIE 260
LE+IKY RG + Y V E+ + I M+VRGAPAIAIV L+LA+E
Sbjct: 4 LEAIKYGRGRLEVLDQLRLPHEFVYDNVSTCEEAFDSIKSMRVRGAPAIAIVAALALAVE 63
Query: 261 L--LKDNIADKKIMRQEIEGKLNYLVSARPTAVNI 359
L KD K+ Q I +L+YL+ +RPTAV++
Sbjct: 64 LHHEKDGSKTKQEAVQYINKRLDYLLGSRPTAVDL 98
>UniRef50_Q06489 Cluster: Methylthioribose-1-phosphate isomerase;
n=6; Saccharomycetales|Rep: Methylthioribose-1-phosphate
isomerase - Saccharomyces cerevisiae (Baker's yeast)
Length = 411
Score = 61.3 bits (142), Expect = 9e-09
Identities = 34/83 (40%), Positives = 54/83 (65%), Gaps = 12/83 (14%)
Frame = +3
Query: 147 TRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSL--AIELLKDN----------IADKK 290
T+YV + ++DG+ VI MQVRGAPAIAIVG LS+ ++L+K N + + +
Sbjct: 30 TKYVPIHTIDDGYSVIKSMQVRGAPAIAIVGSLSVLTEVQLIKHNPTSDVATLYSLVNWE 89
Query: 291 IMRQEIEGKLNYLVSARPTAVNI 359
+ + +L++L+S+RPTAVN+
Sbjct: 90 STKTVLNKRLDFLLSSRPTAVNL 112
>UniRef50_UPI00006CFF79 Cluster: 5-methylthioribose kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
5-methylthioribose kinase family protein - Tetrahymena
thermophila SB210
Length = 779
Score = 57.6 bits (133), Expect = 1e-07
Identities = 26/69 (37%), Positives = 42/69 (60%)
Frame = +3
Query: 156 VKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVS 335
+++ +ED W+VI M VRGAP IA+V L EL + + +R+ + + YL +
Sbjct: 30 IRINTIEDAWKVIKDMNVRGAPLIAVVATQGLRNELFNRDFKSVEELRKYVLQAVEYLRT 89
Query: 336 ARPTAVNIK 362
+RPTAVN++
Sbjct: 90 SRPTAVNLQ 98
>UniRef50_Q67MP0 Cluster: Translation initiation factor eIF-2B alpha
subunit; n=26; Bacteria|Rep: Translation initiation
factor eIF-2B alpha subunit - Symbiobacterium
thermophilum
Length = 359
Score = 56.8 bits (131), Expect = 2e-07
Identities = 28/72 (38%), Positives = 40/72 (55%)
Frame = +3
Query: 144 QTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLN 323
+TRY+++ E+ W I ++VRGAPAI I + L + + AD + E
Sbjct: 28 ETRYLRLTTPEETWEAIRSLRVRGAPAIGIAAAMGLYLGVKGSEAADFEDFYHEFRQVKA 87
Query: 324 YLVSARPTAVNI 359
YL SARPTAVN+
Sbjct: 88 YLASARPTAVNL 99
>UniRef50_Q4Q0R9 Cluster: Translation initiation factor 2 subunit,
putative; n=7; Trypanosomatidae|Rep: Translation
initiation factor 2 subunit, putative - Leishmania major
Length = 506
Score = 56.8 bits (131), Expect = 2e-07
Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 4/98 (4%)
Frame = +3
Query: 78 SLESIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAI 257
+LESIKY GS +T + V VED W I +M+VRGAPAIA+ L +A+
Sbjct: 140 TLESIKYTPGSLRLLDQRKLPLETVFDDVLTVEDIWSAIKEMRVRGAPAIAVSAALGIAV 199
Query: 258 ELLKDNIADKKIMRQEIEGKL----NYLVSARPTAVNI 359
+ + +E++ L ++++++RPTAVN+
Sbjct: 200 ATQRKAANGELKSGREVQTFLLTSCDFVMTSRPTAVNL 237
>UniRef50_A6C0G9 Cluster: Putative translation initiation factor,
aIF-2BI/5-methylthioribose-1- phosphate isomerase; n=1;
Planctomyces maris DSM 8797|Rep: Putative translation
initiation factor, aIF-2BI/5-methylthioribose-1-
phosphate isomerase - Planctomyces maris DSM 8797
Length = 360
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/70 (35%), Positives = 36/70 (51%)
Frame = +3
Query: 150 RYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYL 329
R ++ + VE W I K++VRGAPAI I + I L ++ Q + YL
Sbjct: 37 REIECRDVETVWEAIKKLRVRGAPAIGIAAAYGVVIALQTGTGNERPDFDQRLTEAATYL 96
Query: 330 VSARPTAVNI 359
+RPTAVN+
Sbjct: 97 AESRPTAVNL 106
>UniRef50_Q8F2A8 Cluster: Probable methylthioribose-1-phosphate
isomerase; n=4; Leptospira|Rep: Probable
methylthioribose-1-phosphate isomerase - Leptospira
interrogans
Length = 364
Score = 48.4 bits (110), Expect = 7e-05
Identities = 29/72 (40%), Positives = 44/72 (61%)
Frame = +3
Query: 147 TRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNY 326
T Y+ + +ED I +M VRGAPAIAI G + I L +++ K E++ KL+
Sbjct: 28 TSYITAKTLEDCIFAIREMVVRGAPAIAITG--AFGITLYWNSLVSKPSF-SELKLKLSE 84
Query: 327 LVSARPTAVNIK 362
L+ +RPTAVN++
Sbjct: 85 LLESRPTAVNLR 96
>UniRef50_O31662 Cluster: Methylthioribose-1-phosphate isomerase;
n=17; Bacillaceae|Rep: Methylthioribose-1-phosphate
isomerase - Bacillus subtilis
Length = 353
Score = 48.0 bits (109), Expect = 9e-05
Identities = 27/75 (36%), Positives = 44/75 (58%), Gaps = 3/75 (4%)
Frame = +3
Query: 144 QTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAI---ELLKDNIADKKIMRQEIEG 314
+T Y+++ ED + I ++VRGAPAI I LA+ ++ DN+ + R+ +E
Sbjct: 29 ETEYLELTTKEDVFDAIVTLKVRGAPAIGITAAFGLALAAKDIETDNVTE---FRRRLED 85
Query: 315 KLNYLVSARPTAVNI 359
YL S+RPTA+N+
Sbjct: 86 IKQYLNSSRPTAINL 100
>UniRef50_O29877 Cluster: Putative translation initiation factor
eIF-2B subunit 1; n=10; Archaea|Rep: Putative
translation initiation factor eIF-2B subunit 1 -
Archaeoglobus fulgidus
Length = 339
Score = 47.6 bits (108), Expect = 1e-04
Identities = 22/68 (32%), Positives = 39/68 (57%)
Frame = +3
Query: 156 VKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVS 335
++ + VE+ I K+ VRGAPA+ G +A+ + AD +++ ++ ++L S
Sbjct: 25 IECRNVEELADAIKKLAVRGAPALEAAGAYGIALAAREREFADVDELKEHLKKAADFLAS 84
Query: 336 ARPTAVNI 359
RPTAVN+
Sbjct: 85 TRPTAVNL 92
>UniRef50_A3DN77 Cluster: EIF-2B alpha/beta/delta-related
uncharacterized proteins; n=1; Staphylothermus marinus
F1|Rep: EIF-2B alpha/beta/delta-related uncharacterized
proteins - Staphylothermus marinus (strain ATCC 43588 /
DSM 3639 / F1)
Length = 356
Score = 42.3 bits (95), Expect = 0.005
Identities = 20/58 (34%), Positives = 33/58 (56%)
Frame = +3
Query: 186 RVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVSARPTAVNI 359
+ I +M++RGAPAI + L++A K D +E++ +N L + RPTA N+
Sbjct: 47 KAIIEMEIRGAPAIGVAAALAIASYAYKVKTRDIDSFYREVDSAINILWNTRPTAHNL 104
>UniRef50_A1RWS6 Cluster: EIF-2B alpha/beta/delta-related
uncharacterized proteins; n=1; Thermofilum pendens Hrk
5|Rep: EIF-2B alpha/beta/delta-related uncharacterized
proteins - Thermofilum pendens (strain Hrk 5)
Length = 345
Score = 41.1 bits (92), Expect = 0.010
Identities = 21/69 (30%), Positives = 37/69 (53%)
Frame = +3
Query: 153 YVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLV 332
Y++ E + I M++RGAPAI + ++A+ + + + +E+E +
Sbjct: 29 YIETSSWERVVKAIKDMEIRGAPAIGVAAAYAVALFAVNFPGENLEAFMKELERVAGVVK 88
Query: 333 SARPTAVNI 359
SARPTAVN+
Sbjct: 89 SARPTAVNL 97
>UniRef50_Q4JB92 Cluster: Translation initiation factor eIF-2B alpha
subunit; n=8; Thermoprotei|Rep: Translation initiation
factor eIF-2B alpha subunit - Sulfolobus acidocaldarius
Length = 367
Score = 40.3 bits (90), Expect = 0.018
Identities = 26/69 (37%), Positives = 39/69 (56%)
Frame = +3
Query: 153 YVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLV 332
YV V VE+ I M+VRGAPAI I + + ++D+I+ +K + + K L
Sbjct: 46 YVDVTKVEEVSDAIRTMKVRGAPAIGITAGYGMVL-AIQDSISLEKAISDLTKAK-KILD 103
Query: 333 SARPTAVNI 359
+RPTAVN+
Sbjct: 104 ESRPTAVNL 112
>UniRef50_A5UQK6 Cluster: Putative translation initiation factor,
aIF-2BI family; n=5; Bacteria|Rep: Putative translation
initiation factor, aIF-2BI family - Roseiflexus sp. RS-1
Length = 353
Score = 39.9 bits (89), Expect = 0.024
Identities = 30/76 (39%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
Frame = +3
Query: 144 QTRYVKVQGVEDGWRVINKMQVRGAPAI---AIVGCLSLAIELLKDNIAD-KKIMRQEIE 311
+TR V+ VED I MQ+RGAPAI A G A D + D +I + E
Sbjct: 26 ETRIVRCAAVEDVAYAIRTMQIRGAPAIGCAAAYGMALAACSAAHDAVGDVARIYARLAE 85
Query: 312 GKLNYLVSARPTAVNI 359
K L + RPTAVN+
Sbjct: 86 AKA-LLDAQRPTAVNL 100
>UniRef50_A0LIZ1 Cluster: EIF-2B alpha/beta/delta-related
uncharacterized proteins; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: EIF-2B alpha/beta/delta-related
uncharacterized proteins - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 349
Score = 38.3 bits (85), Expect = 0.074
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = +3
Query: 192 INKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVSARPTAVNI 359
I M +RGAPA+ + G ++LA+ + AD + + + + +ARPT N+
Sbjct: 43 IKNMAIRGAPAVGVAGAMALALGAVLIQAADARTFKSKFARLCRQVRTARPTGRNL 98
>UniRef50_O58433 Cluster: Putative translation initiation factor
eIF-2B subunit 1; n=4; Thermococcaceae|Rep: Putative
translation initiation factor eIF-2B subunit 1 -
Pyrococcus horikoshii
Length = 364
Score = 37.9 bits (84), Expect = 0.097
Identities = 25/91 (27%), Positives = 36/91 (39%)
Frame = +3
Query: 87 SIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELL 266
+++Y+ S + + K VE+ I M VRGAPAI LA+
Sbjct: 16 TVEYKNKSVYMINQRLLPKEFKVEKFSKVEEVAEAIKNMTVRGAPAIGAAAGFGLALYAE 75
Query: 267 KDNIADKKIMRQEIEGKLNYLVSARPTAVNI 359
K+ E L + RPTAVN+
Sbjct: 76 TSKAKTKEEFLDGFEKAYEILKNTRPTAVNL 106
>UniRef50_A1SDR1 Cluster: EIF-2B alpha/beta/delta-related
uncharacterized proteins; n=3; Actinomycetales|Rep:
EIF-2B alpha/beta/delta-related uncharacterized proteins
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 344
Score = 37.5 bits (83), Expect = 0.13
Identities = 23/72 (31%), Positives = 38/72 (52%)
Frame = +3
Query: 144 QTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLN 323
+ RY+ V V+ I + VRGAPA+ VG L + + + + R ++E ++
Sbjct: 25 EERYLDVDTVDALVAAIQSLAVRGAPALGAVGALGVVVAMRQAEREGWDDERLQVE--VD 82
Query: 324 YLVSARPTAVNI 359
+ ARPTAVN+
Sbjct: 83 RIRLARPTAVNL 94
>UniRef50_Q0LDK7 Cluster: Putative translation initiation factor,
aIF-2BI/5-methylthioribose-1- phosphate isomerase; n=2;
Chloroflexi (class)|Rep: Putative translation initiation
factor, aIF-2BI/5-methylthioribose-1- phosphate
isomerase - Herpetosiphon aurantiacus ATCC 23779
Length = 358
Score = 37.1 bits (82), Expect = 0.17
Identities = 19/68 (27%), Positives = 32/68 (47%)
Frame = +3
Query: 156 VKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVS 335
V+ + + I MQVRGAPAI I +A+ + + +++ L +
Sbjct: 32 VRCEDLNSVIEAIRSMQVRGAPAIGITAAYGMALAAQRSTAQTSSKLLEKLAKAKALLDA 91
Query: 336 ARPTAVNI 359
RPTA+N+
Sbjct: 92 TRPTAINL 99
>UniRef50_Q55N23 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 393
Score = 37.1 bits (82), Expect = 0.17
Identities = 25/74 (33%), Positives = 41/74 (55%), Gaps = 5/74 (6%)
Frame = +3
Query: 153 YVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDN--IADKKIMRQEIE--GK- 317
++ V E+ + I M++RGAPAIA + L+L L + ++ I G+
Sbjct: 41 WMPVSTPEEAFDAIKTMRIRGAPAIASLAALTLRSYLSSSSSPVSSSSSSSDVISWVGQT 100
Query: 318 LNYLVSARPTAVNI 359
++YL S+RPTAVN+
Sbjct: 101 IDYLQSSRPTAVNL 114
>UniRef50_Q5H060 Cluster: Initiation factor eIF-2B; n=7;
Gammaproteobacteria|Rep: Initiation factor eIF-2B -
Xanthomonas oryzae pv. oryzae
Length = 449
Score = 36.7 bits (81), Expect = 0.22
Identities = 22/56 (39%), Positives = 30/56 (53%)
Frame = +3
Query: 192 INKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVSARPTAVNI 359
I+ + VRGAPAI I +A+ D Q++E L L +ARPTAVN+
Sbjct: 147 IHSLAVRGAPAIGIAAGWGVALAARDIAADDGNAALQKLEPALLRLNAARPTAVNL 202
>UniRef50_Q9HZ65 Cluster: Probable methylthioribose-1-phosphate
isomerase; n=34; Proteobacteria|Rep: Probable
methylthioribose-1-phosphate isomerase - Pseudomonas
aeruginosa
Length = 358
Score = 36.3 bits (80), Expect = 0.30
Identities = 23/93 (24%), Positives = 43/93 (46%)
Frame = +3
Query: 81 LESIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIE 260
+++I++R G+ + +++ + + + I M VRGAPAI I + +
Sbjct: 11 VKAIEWRDGTLRLLDQRLLPQEEVWLEHESAAEVAKAIRDMVVRGAPAIGISAAYGIVLG 70
Query: 261 LLKDNIADKKIMRQEIEGKLNYLVSARPTAVNI 359
+ +A R +E L +RPTAVN+
Sbjct: 71 -ARARLAQGGDWRAALEEDFRLLADSRPTAVNL 102
>UniRef50_Q2LXN1 Cluster: Methylthioribose salvage protein; n=6;
Bacteria|Rep: Methylthioribose salvage protein -
Syntrophus aciditrophicus (strain SB)
Length = 367
Score = 35.9 bits (79), Expect = 0.39
Identities = 23/97 (23%), Positives = 38/97 (39%)
Frame = +3
Query: 69 LKMSLESIKYRRGSXXXXXXXXXXXQTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLS 248
+ S +I +R + + RY+ E+ I + VRGAPAI + +
Sbjct: 1 MSASFTTIAWRNDAVLLLDQQALPGEERYLTCTRFEEVLTAIRDLTVRGAPAIGVASAMG 60
Query: 249 LAIELLKDNIADKKIMRQEIEGKLNYLVSARPTAVNI 359
+A+ L + E + ARPTA N+
Sbjct: 61 IALGALSLPDDSPEAFCNGFEALCDRFAQARPTARNL 97
>UniRef50_Q2IH96 Cluster: Initiation factor 2B alpha/beta/delta;
n=4; Bacteria|Rep: Initiation factor 2B alpha/beta/delta
- Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 339
Score = 35.9 bits (79), Expect = 0.39
Identities = 22/72 (30%), Positives = 36/72 (50%)
Frame = +3
Query: 144 QTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLN 323
+ R++++ E I + VRGAPAI + +LA+E A + + + +
Sbjct: 30 EERWLELSTAEAVAAAIQDLTVRGAPAIGVAAAYALAVE------ARRGAGPERLRAAAD 83
Query: 324 YLVSARPTAVNI 359
L ARPTAVN+
Sbjct: 84 LLARARPTAVNL 95
>UniRef50_Q1N0Y8 Cluster: Translation initiation factor IF-2B
subunit alpha; n=1; Oceanobacter sp. RED65|Rep:
Translation initiation factor IF-2B subunit alpha -
Oceanobacter sp. RED65
Length = 358
Score = 35.5 bits (78), Expect = 0.52
Identities = 23/72 (31%), Positives = 36/72 (50%)
Frame = +3
Query: 144 QTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLN 323
+ +Y++ I M VRGAPAI I +LA+ A K R + + +N
Sbjct: 31 EIKYIECSDASAVANAIKNMVVRGAPAIGISAAYALAL------AARKLGPRGDYKSIIN 84
Query: 324 YLVSARPTAVNI 359
L ++RPTA+N+
Sbjct: 85 ELSASRPTAINL 96
>UniRef50_Q1FHK8 Cluster: Binding-protein-dependent transport
systems inner membrane component precursor; n=1;
Clostridium phytofermentans ISDg|Rep:
Binding-protein-dependent transport systems inner
membrane component precursor - Clostridium
phytofermentans ISDg
Length = 408
Score = 35.5 bits (78), Expect = 0.52
Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
Frame = -2
Query: 346 VGLADTK*-LSLPSISCRMIFLSAMLSFSNSIARDKQPTIAIAGAPLTCILFMTLHPSST 170
+G+ DT L LPS+ + +L + F SI + + + + GA ILF + P ++
Sbjct: 253 LGIMDTIWALILPSV-VMVYYLLLLKGFFESIPVELEESAKLDGASNFSILFKIIMPIAS 311
Query: 169 PCTLTYLVCKGRSNWSSISKLPLRYLIDSKLILSL-IYIQN 50
P T + W++I+ P+ Y+ ++K I + +YI+N
Sbjct: 312 PMIATVSFFTAITYWNNINN-PILYITNNKSIYPVPMYIKN 351
>UniRef50_Q8R7Q1 Cluster: Sugar permeases; n=4; Bacteria|Rep: Sugar
permeases - Thermoanaerobacter tengcongensis
Length = 289
Score = 33.9 bits (74), Expect = 1.6
Identities = 20/66 (30%), Positives = 30/66 (45%)
Frame = -2
Query: 277 MLSFSNSIARDKQPTIAIAGAPLTCILFMTLHPSSTPCTLTYLVCKGRSNWSSISKLPLR 98
M F SI R+ + + + GA + ILF + P STP +T V + W+ +
Sbjct: 170 MTGFIGSIPREIEESAVMDGAGIFTILFKIIFPLSTPAIVTVTVTTFLTTWNEFI-MAAT 228
Query: 97 YLIDSK 80
YL K
Sbjct: 229 YLTSDK 234
>UniRef50_Q8DK09 Cluster: Translation initiation factor IF-2B alpha
subunit; n=6; Cyanobacteria|Rep: Translation initiation
factor IF-2B alpha subunit - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 355
Score = 33.5 bits (73), Expect = 2.1
Identities = 18/56 (32%), Positives = 28/56 (50%)
Frame = +3
Query: 192 INKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVSARPTAVNI 359
I M VRGAPAI + + + + +D++ +E + L RPTAVN+
Sbjct: 47 IRTMIVRGAPAIGVAAAFGMVLGAREYRGSDREGFLIHLENIASQLRQTRPTAVNL 102
>UniRef50_Q54R90 Cluster: Translation initiation factor eIF-2B alpha
subunit; n=1; Dictyostelium discoideum AX4|Rep:
Translation initiation factor eIF-2B alpha subunit -
Dictyostelium discoideum AX4
Length = 346
Score = 33.5 bits (73), Expect = 2.1
Identities = 21/62 (33%), Positives = 33/62 (53%)
Frame = +3
Query: 174 EDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVSARPTAV 353
ED I ++ VRGAP I + +SL +L + ++ ++EI L +RPTAV
Sbjct: 39 EDMITFIKQLSVRGAPLIGVAASMSLYNHILYN----PQLTKEEIVKVSQELRESRPTAV 94
Query: 354 NI 359
N+
Sbjct: 95 NL 96
>UniRef50_A4W7Z1 Cluster: EIF-2B alpha/beta/delta-related
uncharacterized protein; n=15; Gammaproteobacteria|Rep:
EIF-2B alpha/beta/delta-related uncharacterized protein
- Enterobacter sp. 638
Length = 342
Score = 33.1 bits (72), Expect = 2.8
Identities = 23/72 (31%), Positives = 39/72 (54%)
Frame = +3
Query: 144 QTRYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLN 323
+ R++ VE I+ ++VRGAP I + L LA+ +A+ R ++ L+
Sbjct: 27 EKRWLDASTVEALVGHIHALRVRGAPLIGLSASLLLAL------LAENGHSRDQLAVALD 80
Query: 324 YLVSARPTAVNI 359
L ++RPTAVN+
Sbjct: 81 TLRASRPTAVNL 92
>UniRef50_Q5CXZ3 Cluster: Glycoprotein, putative; n=2;
Cryptosporidium|Rep: Glycoprotein, putative -
Cryptosporidium parvum Iowa II
Length = 594
Score = 33.1 bits (72), Expect = 2.8
Identities = 19/38 (50%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Frame = -2
Query: 178 SSTPCTLTYLVCKGRSNWSSI--SKLPLRYLIDSKLIL 71
S+ CT+ C S+WSSI S+L RY I SKLIL
Sbjct: 452 STKTCTIIKSTCTAPSSWSSIKSSELIARYAILSKLIL 489
>UniRef50_A1S110 Cluster: Glycosyl transferase, family 2; n=1;
Thermofilum pendens Hrk 5|Rep: Glycosyl transferase,
family 2 - Thermofilum pendens (strain Hrk 5)
Length = 353
Score = 33.1 bits (72), Expect = 2.8
Identities = 14/48 (29%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +3
Query: 147 TRYVKVQGVEDGWRVINKM-QVRGAPAIAIVGCLSLAIELLKDNIADK 287
T +KV VE+GWRV+ ++ + RG + +V +++ L++ + D+
Sbjct: 127 TLSIKVSSVEEGWRVLEELCKKRGKIGVELVPAVAMGATLIRKIVLDR 174
>UniRef50_Q2RRC9 Cluster: Sensor protein; n=1; Rhodospirillum rubrum
ATCC 11170|Rep: Sensor protein - Rhodospirillum rubrum
(strain ATCC 11170 / NCIB 8255)
Length = 805
Score = 32.7 bits (71), Expect = 3.7
Identities = 22/68 (32%), Positives = 30/68 (44%)
Frame = +3
Query: 150 RYVKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYL 329
R G E WRV+ P I+ + + I LKDN D + RQ+ E L+ L
Sbjct: 468 RIALANGGERWWRVVAAPTPGEEPDTIILNGVLIDITALKDNERDLRAARQQAEQALSDL 527
Query: 330 VSARPTAV 353
S + T V
Sbjct: 528 RSTQDTLV 535
>UniRef50_P74497 Cluster: Probable methylthioribose-1-phosphate
isomerase; n=28; cellular organisms|Rep: Probable
methylthioribose-1-phosphate isomerase - Synechocystis
sp. (strain PCC 6803)
Length = 351
Score = 32.3 bits (70), Expect = 4.8
Identities = 19/68 (27%), Positives = 30/68 (44%)
Frame = +3
Query: 156 VKVQGVEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVS 335
V + E I M VRGAPAI + + + + + + ++E + L
Sbjct: 35 VAIADYEAMGHAIKSMVVRGAPAIGVAAAYGMYLGARRIQTTELREFVVQLEFVADQLRQ 94
Query: 336 ARPTAVNI 359
RPTAVN+
Sbjct: 95 TRPTAVNL 102
>UniRef50_Q2FN46 Cluster: Putative translation initiation factor,
aIF-2BI/5-methylthioribose-1- phosphate isomerase; n=2;
Methanomicrobiales|Rep: Putative translation initiation
factor, aIF-2BI/5-methylthioribose-1- phosphate
isomerase - Methanospirillum hungatei (strain JF-1 / DSM
864)
Length = 354
Score = 31.9 bits (69), Expect = 6.4
Identities = 17/63 (26%), Positives = 28/63 (44%)
Frame = +3
Query: 171 VEDGWRVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVSARPTA 350
+ D I ++ +RGAPA+ G +A+ L ++ + L RPTA
Sbjct: 38 IPDLAEAIKRLGIRGAPALGCAGGCGVALSALITKADSLPEFLDQVGSDADLLRKTRPTA 97
Query: 351 VNI 359
VN+
Sbjct: 98 VNL 100
>UniRef50_O57947 Cluster: Putative translation initiation factor
eIF-2B subunit 2; n=10; Euryarchaeota|Rep: Putative
translation initiation factor eIF-2B subunit 2 -
Pyrococcus horikoshii
Length = 324
Score = 31.9 bits (69), Expect = 6.4
Identities = 17/56 (30%), Positives = 29/56 (51%)
Frame = +3
Query: 192 INKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVSARPTAVNI 359
I M++RGA IA +L I+ K + + + E++ L + RPTAV++
Sbjct: 16 IKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSL 71
>UniRef50_UPI0000F1E8D9 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 307
Score = 31.5 bits (68), Expect = 8.5
Identities = 25/80 (31%), Positives = 36/80 (45%)
Frame = -2
Query: 319 SLPSISCRMIFLSAMLSFSNSIARDKQPTIAIAGAPLTCILFMTLHPSSTPCTLTYLVCK 140
S P IS + SA + ++ A P I+IA C + STPCT T +C
Sbjct: 161 SAPCISIASV--SAPCTSTSETASVSSPCISIASVSSLCTSAPEISSVSTPCTSTPELCD 218
Query: 139 GRSNWSSISKLPLRYLIDSK 80
S+ S+ PL ++D K
Sbjct: 219 -----STPSQFPLDSVVDRK 233
>UniRef50_Q9RXY2 Cluster: Putative uncharacterized protein; n=1;
Deinococcus radiodurans|Rep: Putative uncharacterized
protein - Deinococcus radiodurans
Length = 271
Score = 31.5 bits (68), Expect = 8.5
Identities = 17/47 (36%), Positives = 22/47 (46%)
Frame = -2
Query: 217 APLTCILFMTLHPSSTPCTLTYLVCKGRSNWSSISKLPLRYLIDSKL 77
APL ++ HPS T L C RSNW S ++ L Y +L
Sbjct: 42 APLPVWCWLIEHPSGLIVVDTGLTCTARSNWFSRTQTRLHYTEHDRL 88
>UniRef50_Q8TWU6 Cluster: Predicted RNA-binding protein, contains
THUMP domain; n=1; Methanopyrus kandleri|Rep: Predicted
RNA-binding protein, contains THUMP domain -
Methanopyrus kandleri
Length = 278
Score = 31.5 bits (68), Expect = 8.5
Identities = 17/54 (31%), Positives = 35/54 (64%), Gaps = 1/54 (1%)
Frame = +3
Query: 186 RVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQ-EIEGKLNYLVSARP 344
+++N++ R A + G +A+E D A++K++R+ ++EGK+ + V+ARP
Sbjct: 14 KILNEIPKRTVTAALLEGGEIVAVEEADDEHAERKLVRRHDVEGKVVF-VTARP 66
>UniRef50_Q9YE84 Cluster: Putative translation initiation factor
eIF-2B subunit 1; n=4; Thermoprotei|Rep: Putative
translation initiation factor eIF-2B subunit 1 -
Aeropyrum pernix
Length = 370
Score = 31.5 bits (68), Expect = 8.5
Identities = 17/58 (29%), Positives = 28/58 (48%)
Frame = +3
Query: 186 RVINKMQVRGAPAIAIVGCLSLAIELLKDNIADKKIMRQEIEGKLNYLVSARPTAVNI 359
R I M++RGAPAI + +LA+ + + + + + S RPTA N+
Sbjct: 58 RAIVDMEIRGAPAIGVAAAYALALAAAEAASRGGEGFIEALSEARREIESTRPTAYNL 115
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 361,580,656
Number of Sequences: 1657284
Number of extensions: 6024726
Number of successful extensions: 12277
Number of sequences better than 10.0: 45
Number of HSP's better than 10.0 without gapping: 12035
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12262
length of database: 575,637,011
effective HSP length: 93
effective length of database: 421,509,599
effective search space used: 22761518346
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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