Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I09A02NGRL0001_E07
(658 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B58FD Cluster: PREDICTED: similar to rho/rac-in... 64 2e-09
UniRef50_UPI0000DB7276 Cluster: PREDICTED: similar to citron iso... 64 2e-09
UniRef50_Q9VTY8 Cluster: CG10522-PA; n=4; Sophophora|Rep: CG1052... 59 8e-08
UniRef50_Q16NS1 Cluster: Citron ser/thr kinase; n=3; Culicidae|R... 52 1e-05
UniRef50_Q21025 Cluster: Putative uncharacterized protein; n=3; ... 48 2e-04
UniRef50_O14578 Cluster: Citron Rho-interacting kinase; n=56; Eu... 45 0.001
UniRef50_Q6DT37 Cluster: Serine/threonine-protein kinase MRCK ga... 42 0.017
UniRef50_UPI0000EB1830 Cluster: Serine/threonine-protein kinase ... 40 0.053
UniRef50_Q54EH3 Cluster: Rap/ran-GAP domain-containing protein; ... 37 0.37
UniRef50_Q5KCD5 Cluster: Rab guanyl-nucleotide exchange factor, ... 37 0.37
UniRef50_UPI00006A08A1 Cluster: Serine/threonine-protein kinase ... 36 0.86
UniRef50_A7E5X2 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1
UniRef50_A7SF24 Cluster: Predicted protein; n=3; Nematostella ve... 34 3.5
UniRef50_Q5T7A0 Cluster: CDC42 binding protein kinase alpha; n=1... 34 3.5
UniRef50_Q5VT25 Cluster: Serine/threonine-protein kinase MRCK al... 34 3.5
UniRef50_Q16L65 Cluster: Protein phosphatase 1 regulatory subuni... 33 8.0
UniRef50_Q6BWS6 Cluster: Similar to CA4444|IPF3533 Candida albic... 33 8.0
UniRef50_Q9NS56 Cluster: E3 ubiquitin-protein ligase Topors; n=2... 33 8.0
>UniRef50_UPI00015B58FD Cluster: PREDICTED: similar to
rho/rac-interacting citron kinase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
rho/rac-interacting citron kinase - Nasonia vitripennis
Length = 1545
Score = 64.5 bits (150), Expect = 2e-09
Identities = 30/60 (50%), Positives = 38/60 (63%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIVGEEKVTIIYLSEEAYK 411
EI +CY E GVFV+ENG+RTR+ DP WS + F P+L+IV V II L +YK
Sbjct: 1391 EILLCYNEFGVFVNENGQRTRSIDPTWSHLPFAFAFRKPYLFIVHFSSVEIIKLDSSSYK 1450
>UniRef50_UPI0000DB7276 Cluster: PREDICTED: similar to citron isoform
2; n=1; Apis mellifera|Rep: PREDICTED: similar to citron
isoform 2 - Apis mellifera
Length = 1394
Score = 64.5 bits (150), Expect = 2e-09
Identities = 27/59 (45%), Positives = 39/59 (66%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIVGEEKVTIIYLSEEAY 408
E+ +CY E G+FV+ENG+RTRN DP W+ + F P+L+I+ V I+ L +EAY
Sbjct: 1240 ELLLCYNEFGMFVNENGQRTRNIDPTWNHLPFAFAFRKPYLFIIHFSSVEIVKLDQEAY 1298
>UniRef50_Q9VTY8 Cluster: CG10522-PA; n=4; Sophophora|Rep: CG10522-PA
- Drosophila melanogaster (Fruit fly)
Length = 1854
Score = 59.3 bits (137), Expect = 8e-08
Identities = 40/131 (30%), Positives = 60/131 (45%)
Frame = +1
Query: 1 DASASEFKISRSLTIDRPPTSLLLTSRYLFITGEKPLKINLPSGALESFAMDEPTVXXXX 180
D FK R+L P TS+ T ++ +K +I+L + A E F
Sbjct: 1629 DLKLHMFKPVRALDTATPVTSIFFTRHSAIVSSDKFYEIDLDNYAAEEFVDLSDKSMEST 1688
Query: 181 XXXXXXXXILLIREKPFEIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYI 360
+ + R+ E +C+AE GVFVDE G R+R D W A G+ + +PFL+I
Sbjct: 1689 AKCQPLTAVRISRQ---EYLLCFAEYGVFVDEFGCRSRPYDLNWVYAPTGFVYRDPFLFI 1745
Query: 361 VGEEKVTIIYL 393
+ V I+ L
Sbjct: 1746 SHYQSVQIVRL 1756
>UniRef50_Q16NS1 Cluster: Citron ser/thr kinase; n=3; Culicidae|Rep:
Citron ser/thr kinase - Aedes aegypti (Yellowfever
mosquito)
Length = 1851
Score = 52.0 bits (119), Expect = 1e-05
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 1/138 (0%)
Frame = +1
Query: 1 DASASEFKISRSLTIDRPPTSLLLTSRYLFITGEKPLKINLPS-GALESFAMDEPTVXXX 177
D S FK R L P TS+L T ++ +K +I+L + GA E M + ++
Sbjct: 1625 DTSLGRFKPVRGLDTVLPVTSVLFTKHTAIVSSDKFFEIDLGTYGAEEFLDMSDSSLRDI 1684
Query: 178 XXXXXXXXXILLIREKPFEIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLY 357
+ + E +C+ E G+FVDE G R+R ++ W + + L+
Sbjct: 1685 RSCSP----MAAFKVNSQEFLLCFKEVGIFVDEYGCRSRPDNINWLQEPLDFRYRESCLF 1740
Query: 358 IVGEEKVTIIYLSEEAYK 411
I + V ++Y+S+ K
Sbjct: 1741 IAHSDCVQVMYVSKSYTK 1758
>UniRef50_Q21025 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 1286
Score = 48.0 bits (109), Expect = 2e-04
Identities = 19/56 (33%), Positives = 36/56 (64%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIVGEEKVTIIYLSE 399
E+ + Y G+FV+ +G+++RNE +W + + +PFLYIV ++ + I+ +SE
Sbjct: 1159 EVLLAYQNQGIFVNLHGEQSRNETIEWEKMPMEFIYTSPFLYIVHDDSIEILEISE 1214
>UniRef50_O14578 Cluster: Citron Rho-interacting kinase; n=56;
Eumetazoa|Rep: Citron Rho-interacting kinase - Homo
sapiens (Human)
Length = 2027
Score = 45.2 bits (102), Expect = 0.001
Identities = 18/52 (34%), Positives = 30/52 (57%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIVGEEKVTII 387
E +C+ E GVFVD G+R+R +D KWS + + P+L++ + +I
Sbjct: 1799 EYLLCFHEFGVFVDSYGRRSRTDDLKWSRLPLAFAYREPYLFVTHFNSLEVI 1850
>UniRef50_Q6DT37 Cluster: Serine/threonine-protein kinase MRCK gamma;
n=11; Eutheria|Rep: Serine/threonine-protein kinase MRCK
gamma - Homo sapiens (Human)
Length = 1551
Score = 41.5 bits (93), Expect = 0.017
Identities = 14/51 (27%), Positives = 27/51 (52%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIVGEEKVTI 384
E + + G++VD G+++R + W AA GW + P+L + E + +
Sbjct: 1289 EFLLLFTTAGIYVDGAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDV 1339
>UniRef50_UPI0000EB1830 Cluster: Serine/threonine-protein kinase MRCK
gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma)
(Myotonic dystrophy kinase-related CDC42-binding kinase
gamma) (Myotonic dystrophy protein kinase-like alpha)
(MRCK gamma) (DMPK-like gamma).; n=1; Canis lupus
familiaris|Rep: Serine/threonine-protein kinase MRCK
gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma)
(Myotonic dystrophy kinase-related CDC42-binding kinase
gamma) (Myotonic dystrophy protein kinase-like alpha)
(MRCK gamma) (DMPK-like gamma). - Canis familiaris
Length = 1597
Score = 39.9 bits (89), Expect = 0.053
Identities = 14/51 (27%), Positives = 26/51 (50%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIVGEEKVTI 384
E + + GV+VD G+++R + W A GW + P+L + E + +
Sbjct: 1432 EFLLLFTTAGVYVDSAGRKSRVHELLWPAVPTGWGYAAPYLTVFSENSIDV 1482
>UniRef50_Q54EH3 Cluster: Rap/ran-GAP domain-containing protein;
n=1; Dictyostelium discoideum AX4|Rep: Rap/ran-GAP
domain-containing protein - Dictyostelium discoideum AX4
Length = 1031
Score = 37.1 bits (82), Expect = 0.37
Identities = 13/29 (44%), Positives = 20/29 (68%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSA 318
EI +C+ G+FVDE+G +TR + KW +
Sbjct: 804 EILLCFNNIGIFVDESGNKTRQFELKWGS 832
>UniRef50_Q5KCD5 Cluster: Rab guanyl-nucleotide exchange factor,
putative; n=2; Filobasidiella neoformans|Rep: Rab
guanyl-nucleotide exchange factor, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 1036
Score = 37.1 bits (82), Expect = 0.37
Identities = 14/44 (31%), Positives = 21/44 (47%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIV 363
E+ + + GVF G TR W + HG F NP++Y +
Sbjct: 270 EVLLARQDTGVFYSSEGNYTRQRSVHWPSPPHGIAFSNPYIYSI 313
>UniRef50_UPI00006A08A1 Cluster: Serine/threonine-protein kinase MRCK
gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma)
(Myotonic dystrophy kinase-related CDC42-binding kinase
gamma) (Myotonic dystrophy protein kinase-like alpha)
(MRCK gamma) (DMPK-like gamma).; n=1; Xenopus
tropicalis|Rep: Serine/threonine-protein kinase MRCK
gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma)
(Myotonic dystrophy kinase-related CDC42-binding kinase
gamma) (Myotonic dystrophy protein kinase-like alpha)
(MRCK gamma) (DMPK-like gamma). - Xenopus tropicalis
Length = 1564
Score = 35.9 bits (79), Expect = 0.86
Identities = 14/51 (27%), Positives = 26/51 (50%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIVGEEKVTI 384
E +C++ GV+VD G+++R ++ W A + P L + E + I
Sbjct: 1386 EFLLCFSTFGVYVDSQGRKSRTQEIMWPAPPVACVYTAPHLTVFSENALDI 1436
>UniRef50_A7E5X2 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 1735
Score = 35.5 bits (78), Expect = 1.1
Identities = 13/29 (44%), Positives = 21/29 (72%)
Frame = +1
Query: 211 LIREKPFEIFICYAECGVFVDENGKRTRN 297
+ R E +CYAECGV+VD++G+ +R+
Sbjct: 1606 MFRLSDAEFLLCYAECGVYVDKHGEVSRS 1634
>UniRef50_A7SF24 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 886
Score = 33.9 bits (74), Expect = 3.5
Identities = 14/43 (32%), Positives = 24/43 (55%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYI 360
E +C+ E GVFV+ G++TR + W+ + PFL++
Sbjct: 782 EFLLCFNEFGVFVNGAGRQTREKTLMWTRLPLAVAYNAPFLFV 824
>UniRef50_Q5T7A0 Cluster: CDC42 binding protein kinase alpha; n=14;
Eumetazoa|Rep: CDC42 binding protein kinase alpha - Homo
sapiens (Human)
Length = 727
Score = 33.9 bits (74), Expect = 3.5
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIVGEEKVTI 384
E +C+ G++ D G+R+R ++ W A + P+L + E V I
Sbjct: 633 EYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDI 683
>UniRef50_Q5VT25 Cluster: Serine/threonine-protein kinase MRCK alpha;
n=56; Euteleostomi|Rep: Serine/threonine-protein kinase
MRCK alpha - Homo sapiens (Human)
Length = 1732
Score = 33.9 bits (74), Expect = 3.5
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIVGEEKVTI 384
E +C+ G++ D G+R+R ++ W A + P+L + E V I
Sbjct: 1422 EYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDI 1472
>UniRef50_Q16L65 Cluster: Protein phosphatase 1 regulatory subunit
12b; n=1; Aedes aegypti|Rep: Protein phosphatase 1
regulatory subunit 12b - Aedes aegypti (Yellowfever
mosquito)
Length = 934
Score = 32.7 bits (71), Expect = 8.0
Identities = 16/27 (59%), Positives = 19/27 (70%)
Frame = +1
Query: 1 DASASEFKISRSLTIDRPPTSLLLTSR 81
DASASE ++S S TI PP+S L T R
Sbjct: 517 DASASEQQVSASFTISAPPSSSLSTRR 543
>UniRef50_Q6BWS6 Cluster: Similar to CA4444|IPF3533 Candida albicans
IPF3533 putative GDP/GTP exchange factor; n=1;
Debaryomyces hansenii|Rep: Similar to CA4444|IPF3533
Candida albicans IPF3533 putative GDP/GTP exchange factor
- Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 1481
Score = 32.7 bits (71), Expect = 8.0
Identities = 15/56 (26%), Positives = 30/56 (53%)
Frame = +1
Query: 232 EIFICYAECGVFVDENGKRTRNEDPKWSAAVHGWEFVNPFLYIVGEEKVTIIYLSE 399
E + Y +C +F +++GK +R K+ F+N L++V +E + I +S+
Sbjct: 1375 EFLLVYNDCAIFTNKHGKLSRYSMLKFEFKAKTIAFINNHLFLVCDEVMEIWSISD 1430
>UniRef50_Q9NS56 Cluster: E3 ubiquitin-protein ligase Topors; n=22;
Euteleostomi|Rep: E3 ubiquitin-protein ligase Topors -
Homo sapiens (Human)
Length = 1045
Score = 32.7 bits (71), Expect = 8.0
Identities = 19/56 (33%), Positives = 32/56 (57%)
Frame = +2
Query: 158 NRRSPLQLKNNRHLKRYF*YARNLSKFLSATRNAACSSMRTGSVRATRIPSGVRRY 325
+ R+ + KNN ++Y+ Y R+ S+ LS+ R+ S+ T VR + P G R+Y
Sbjct: 745 SERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTAST-GTDRVRNEK-PGGKRKY 798
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 587,060,633
Number of Sequences: 1657284
Number of extensions: 10921317
Number of successful extensions: 29937
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 29124
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 29933
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49586781480
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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