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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= I09A02NGRL0001_D09
         (501 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q15084 Cluster: Protein disulfide-isomerase A6 precurso...   189   4e-47
UniRef50_Q5DFE8 Cluster: SJCHGC05888 protein; n=1; Schistosoma j...   122   5e-27
UniRef50_Q9XTU8 Cluster: Putative uncharacterized protein; n=2; ...   118   7e-26
UniRef50_Q9MAU6 Cluster: F13M7.3 protein; n=10; Magnoliophyta|Re...    93   4e-18
UniRef50_Q22XT0 Cluster: Protein disulfide-isomerase domain cont...    75   1e-12
UniRef50_Q5CY16 Cluster: Protein disulfide isomerase, signal pep...    67   2e-10
UniRef50_UPI0000E49DA6 Cluster: PREDICTED: similar to ENSANGP000...    66   3e-10
UniRef50_A0BDV3 Cluster: Chromosome undetermined scaffold_101, w...    54   1e-06
UniRef50_Q16U14 Cluster: Putative uncharacterized protein; n=1; ...    51   2e-05
UniRef50_Q869Z0 Cluster: Similar to Aspergillus niger. PDI relat...    39   0.073
UniRef50_A4RY42 Cluster: Predicted protein; n=2; Ostreococcus|Re...    37   0.22 
UniRef50_Q7R984 Cluster: Thioredoxin, putative; n=6; Plasmodium|...    36   0.68 
UniRef50_A2EL28 Cluster: Putative uncharacterized protein; n=11;...    33   3.6  
UniRef50_Q6CJ44 Cluster: Similar to sgd|S0002744 Saccharomyces c...    33   3.6  
UniRef50_UPI0000DB77ED Cluster: PREDICTED: similar to CG15455-PA...    33   4.8  
UniRef50_A7BPM5 Cluster: Secreted protein; n=1; Beggiatoa sp. PS...    32   6.3  
UniRef50_A1VHJ4 Cluster: RND efflux system, outer membrane lipop...    32   6.3  
UniRef50_Q6C6T9 Cluster: Yarrowia lipolytica chromosome E of str...    32   6.3  
UniRef50_Q6UX30 Cluster: SAMK3000; n=1; Homo sapiens|Rep: SAMK30...    32   8.3  

>UniRef50_Q15084 Cluster: Protein disulfide-isomerase A6 precursor;
           n=54; Eumetazoa|Rep: Protein disulfide-isomerase A6
           precursor - Homo sapiens (Human)
          Length = 440

 Score =  189 bits (460), Expect = 4e-47
 Identities = 86/127 (67%), Positives = 98/127 (77%), Gaps = 3/127 (2%)
 Frame = +3

Query: 3   NDYISILKRLGDKYKSKMWGWIWAEAAAQPTLEEALELGGFGYPAMAVVNAKKLKFSTLR 182
           N Y+ +L +L DKYK KMWGW+W EA AQ  LE AL +GGFGYPAMA +NA+K+KF+ L+
Sbjct: 314 NSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFALLK 373

Query: 183 GSFSETGINEFLRGLSFGRGQTAPVKGAEMPKITTTEPWDGNDGELPLEEDIDLSDV--- 353
           GSFSE GINEFLR LSFGRG TAPV G   P I   EPWDG DGELP+E+DIDLSDV   
Sbjct: 374 GSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELD 433

Query: 354 DLEKDEL 374
           DL KDEL
Sbjct: 434 DLGKDEL 440


>UniRef50_Q5DFE8 Cluster: SJCHGC05888 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC05888 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 416

 Score =  122 bits (294), Expect = 5e-27
 Identities = 56/118 (47%), Positives = 78/118 (66%), Gaps = 1/118 (0%)
 Frame = +3

Query: 9   YISILKRLGDKYKSKMWGWIWAEAAAQPTLEEALELGGFGYPAMAVVNAKKLKFSTLRGS 188
           Y+ +LK   DK+K + WGWIW EA   P LE+A ++GG GYPAM  V+ +K K +TLRG+
Sbjct: 301 YLDLLKTEADKFKKQKWGWIWTEALKHPELEKAFDIGGSGYPAMVAVHGRKKKRTTLRGA 360

Query: 189 FSETGINEFLRGLSFGRGQTAPVKGA-EMPKITTTEPWDGNDGELPLEEDIDLSDVDL 359
           +S   +++FLR LS G G T P+     +P++ T EPWDG D + P+EED D   V+L
Sbjct: 361 YSSNSVHDFLRTLSVG-GATLPLFDVNSLPEVKTVEPWDGKDAQ-PIEEDYDDLKVEL 416


>UniRef50_Q9XTU8 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 436

 Score =  118 bits (284), Expect = 7e-26
 Identities = 54/126 (42%), Positives = 79/126 (62%), Gaps = 5/126 (3%)
 Frame = +3

Query: 12  ISILKRLGDKYKSKMWGWIWAEAAAQPTLEEALELGGFGYPAMAVVNAKKLKFSTLRGSF 191
           I +L  L   +K + +GW+W E  AQ  ++ A E+G +G+P +  ++ KK+ +ST  G F
Sbjct: 311 IDMLNELATIFKKRSFGWVWMEGGAQENVQRAFEIGDYGFPVLIAMSPKKMMYSTQIGQF 370

Query: 192 SETGINEFLRGLSFGRGQTAPVKGAEMP----KITTTEPWDGNDGELPLEEDIDLSDVDL 359
           S  GI EFL  +++G+G+   +K   +     KI  T+PWDG D ELP+ EDIDLSDVD+
Sbjct: 371 SVDGIKEFLNAVNYGKGRVLEIKPTHLSNNFLKIVETQPWDGKDKELPVMEDIDLSDVDM 430

Query: 360 -EKDEL 374
            EK EL
Sbjct: 431 DEKTEL 436


>UniRef50_Q9MAU6 Cluster: F13M7.3 protein; n=10; Magnoliophyta|Rep:
           F13M7.3 protein - Arabidopsis thaliana (Mouse-ear cress)
          Length = 443

 Score = 92.7 bits (220), Expect = 4e-18
 Identities = 43/123 (34%), Positives = 69/123 (56%)
 Frame = +3

Query: 3   NDYISILKRLGDKYKSKMWGWIWAEAAAQPTLEEALELGGFGYPAMAVVNAKKLKFSTLR 182
           N Y+ +L  + DK+K   +G++W  A  QP LE+ + +GG+GYPAM  +NAKK  ++ L+
Sbjct: 314 NKYLEMLLSVADKFKKDPYGFVWVAAGKQPDLEKRVGVGGYGYPAMVALNAKKGAYAPLK 373

Query: 183 GSFSETGINEFLRGLSFGRGQTAPVKGAEMPKITTTEPWDGNDGELPLEEDIDLSDVDLE 362
             F    + +F++  + G     P+ G    +I  TE WDG DGE+   ++  L D+   
Sbjct: 374 SGFEVKHLKDFVKEAAKGGKGNLPIDGT--MEIVKTEAWDGKDGEVVDADEFSLEDLMGN 431

Query: 363 KDE 371
            DE
Sbjct: 432 DDE 434


>UniRef50_Q22XT0 Cluster: Protein disulfide-isomerase domain
           containing protein; n=3; Oligohymenophorea|Rep: Protein
           disulfide-isomerase domain containing protein -
           Tetrahymena thermophila SB210
          Length = 430

 Score = 74.5 bits (175), Expect = 1e-12
 Identities = 35/114 (30%), Positives = 59/114 (51%)
 Frame = +3

Query: 3   NDYISILKRLGDKYKSKMWGWIWAEAAAQPTLEEALELGGFGYPAMAVVNAKKLKFSTLR 182
           N YI+++  +    K +   ++W++   Q   EE L  GG GYP+   ++ KK  +   +
Sbjct: 319 NGYINLITEIAQANKGRPITYLWSQGGDQYDFEEKLNAGGSGYPSAMAISHKKNLYQIFK 378

Query: 183 GSFSETGINEFLRGLSFGRGQTAPVKGAEMPKITTTEPWDGNDGELPLEEDIDL 344
           GSF +  ++ F+ GL  GRG  + +    +PKI   + WDG D E    ++ DL
Sbjct: 379 GSFKKKDLDSFISGLLTGRGSFSTL--PTLPKIKKVKEWDGQDAEQQQTDNSDL 430


>UniRef50_Q5CY16 Cluster: Protein disulfide isomerase, signal
           peptide, ER retention motif; n=2; Cryptosporidium|Rep:
           Protein disulfide isomerase, signal peptide, ER
           retention motif - Cryptosporidium parvum Iowa II
          Length = 451

 Score = 66.9 bits (156), Expect = 2e-10
 Identities = 37/122 (30%), Positives = 63/122 (51%)
 Frame = +3

Query: 9   YISILKRLGDKYKSKMWGWIWAEAAAQPTLEEALELGGFGYPAMAVVNAKKLKFSTLRGS 188
           Y+ I K +     +    ++W+E  +Q   EE L L  FGYPA+  +N +K +FST RGS
Sbjct: 333 YLKIYKDVVSASAAMTIRFLWSEGGSQFDFEEKLNLA-FGYPAVVAINNEKQRFSTHRGS 391

Query: 189 FSETGINEFLRGLSFGRGQTAPVKGAEMPKITTTEPWDGNDGELPLEEDIDLSDVDLEKD 368
           F+   +N F+  L+ GR    P+   ++PKI+    W+    +     + + +  + + D
Sbjct: 392 FTVESLNSFIIALTTGRAPVDPL--PKLPKISKVSSWEPKKSKENSNAEENRNKSNRQSD 449

Query: 369 EL 374
           EL
Sbjct: 450 EL 451


>UniRef50_UPI0000E49DA6 Cluster: PREDICTED: similar to
           ENSANGP00000020140; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to ENSANGP00000020140
           - Strongylocentrotus purpuratus
          Length = 399

 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 26/49 (53%), Positives = 36/49 (73%)
 Frame = +3

Query: 225 LSFGRGQTAPVKGAEMPKITTTEPWDGNDGELPLEEDIDLSDVDLEKDE 371
           +S GRG +  ++G  +P I T EPWDG DGE+P E+DIDLSD D++ D+
Sbjct: 338 VSVGRGSSESIRGDALPSIETKEPWDGKDGEMPEEDDIDLSDFDMDDDD 386


>UniRef50_A0BDV3 Cluster: Chromosome undetermined scaffold_101,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_101,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 417

 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 27/81 (33%), Positives = 42/81 (51%)
 Frame = +3

Query: 9   YISILKRLGDKYKSKMWGWIWAEAAAQPTLEEALELGGFGYPAMAVVNAKKLKFSTLRGS 188
           Y++  +      KSK     W++A  Q  LEE   L G GYP++  ++ KK  FS +RGS
Sbjct: 324 YLNTYRETVKPLKSKPLVHFWSQAGDQYELEEQFGLSGAGYPSVLALSPKKQLFSKMRGS 383

Query: 189 FSETGINEFLRGLSFGRGQTA 251
            +   ++ FL  L  G+ Q +
Sbjct: 384 LTSANVDRFLNNLLSGKEQVS 404


>UniRef50_Q16U14 Cluster: Putative uncharacterized protein; n=1;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 161

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 27/83 (32%), Positives = 44/83 (53%)
 Frame = -2

Query: 371 LILL*VDIGEVYVLFERQLAVVAVPGLRRGDLGHLGAFYRRSLASTERETSEEFIDAXXX 192
           ++L+ + IG++ VLF R+L V+AVPGL   +LG  G   R  +  T  + S+E +DA   
Sbjct: 32  ILLVQIHIGQIDVLFFRKLPVLAVPGLDVVNLGQCGTLDRSRVPPTVGQISQELVDAFLR 91

Query: 191 XXXXXXXXXEFLRVDNSHGRVTE 123
                      L +D+ H R+ +
Sbjct: 92  EGSTQQRVLHLLDIDDGHRRIAK 114


>UniRef50_Q869Z0 Cluster: Similar to Aspergillus niger. PDI related
           protein A; n=2; Dictyostelium discoideum|Rep: Similar to
           Aspergillus niger. PDI related protein A - Dictyostelium
           discoideum (Slime mold)
          Length = 409

 Score = 38.7 bits (86), Expect = 0.073
 Identities = 20/95 (21%), Positives = 44/95 (46%)
 Frame = +3

Query: 9   YISILKRLGDKYKSKMWGWIWAEAAAQPTLEEALELGGFGYPAMAVVNAKKLKFSTLRGS 188
           Y+ +L  +   +  +M  ++W + +    +    +L G   P + V+N  K +++   GS
Sbjct: 313 YLELLNTVSQNFIGRM-KFVWVDVSVHDKIVPQFDLSGT--PNIFVINNSKKRYTPFMGS 369

Query: 189 FSETGINEFLRGLSFGRGQTAPVKGAEMPKITTTE 293
           FS+  +N F + +  G  +  P    + PK  + +
Sbjct: 370 FSDESLNSFFKSVLSGLKKAIPF--TDSPKFNSQQ 402


>UniRef50_A4RY42 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 753

 Score = 37.1 bits (82), Expect = 0.22
 Identities = 24/82 (29%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
 Frame = +3

Query: 129 YPAMAVVNAKKLKFSTLRGSFSETGINEFLRGLSFGRGQTAPVKGAEMPKITT-TEPWDG 305
           YP + V+  +  +++T +G+F E  + +F   +  G+ +T   +  EMPK+    E  + 
Sbjct: 617 YPTVTVLAMRTSRYATHKGAFDEIAVRDFCTDILGGKVKT--WRFQEMPKLVEGGETVEE 674

Query: 306 NDGELPLEEDIDLSDVDLEKDE 371
              E  +EE+ DLSD+  E+ E
Sbjct: 675 IVEEEIVEEEFDLSDIMSEEVE 696


>UniRef50_Q7R984 Cluster: Thioredoxin, putative; n=6;
           Plasmodium|Rep: Thioredoxin, putative - Plasmodium
           yoelii yoelii
          Length = 438

 Score = 35.5 bits (78), Expect = 0.68
 Identities = 17/58 (29%), Positives = 31/58 (53%)
 Frame = +3

Query: 66  IWAEAAAQPTLEEALELGGFGYPAMAVVNAKKLKFSTLRGSFSETGINEFLRGLSFGR 239
           +W  A  Q  + + L L  FG+P +  ++  K  +S L+G++SE  I  F+  +  G+
Sbjct: 338 MWTHAGDQLDIVQKLNLT-FGFPTVIAISFSKNVYSILKGNYSEQSIKNFVIQMMTGK 394


>UniRef50_A2EL28 Cluster: Putative uncharacterized protein; n=11;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 4994

 Score = 33.1 bits (72), Expect = 3.6
 Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
 Frame = +3

Query: 120 GFGYPAMAVVNAKKLKFSTLRGSF-SETGINEFLRGLSFGRGQTAPVKG 263
           GFG  ++AV  AK LKF+  + SF +ET +++ +  ++  RG +   KG
Sbjct: 589 GFGKTSVAVALAKGLKFNPYKVSFNAETKLSDLIGNITITRGTSDNSKG 637


>UniRef50_Q6CJ44 Cluster: Similar to sgd|S0002744 Saccharomyces
           cerevisiae YDR336w; n=1; Kluyveromyces lactis|Rep:
           Similar to sgd|S0002744 Saccharomyces cerevisiae YDR336w
           - Kluyveromyces lactis (Yeast) (Candida sphaerica)
          Length = 359

 Score = 33.1 bits (72), Expect = 3.6
 Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
 Frame = +3

Query: 207 NEFLRGLSFGRGQ-TAPVKGAEMPKITTTEPWDGNDGELPLE 329
           NEF+   +F +G  T PV   ++P+I + + + G  G +P E
Sbjct: 123 NEFIASTTFKKGSMTLPVASEDVPQINSNKMYQGKTGGIPFE 164


>UniRef50_UPI0000DB77ED Cluster: PREDICTED: similar to CG15455-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to
           CG15455-PA - Apis mellifera
          Length = 618

 Score = 32.7 bits (71), Expect = 4.8
 Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
 Frame = -3

Query: 241 PRPNERPLRNSLMPVS----EKDPLRVE-NLSFFALTTAMAG*PNPPSSKASSRVGCAAA 77
           P PN  P RN L P+S    E  P     N     LTTA    P PP+   ++    + +
Sbjct: 304 PGPNSEPSRNDLGPISVSVREVTPTTSPGNPGPGLLTTATVAAPTPPAEPTTTTTTPSPS 363

Query: 76  SAHIHPHILLLYL 38
           S H H H   L+L
Sbjct: 364 SGH-HSHFQGLHL 375


>UniRef50_A7BPM5 Cluster: Secreted protein; n=1; Beggiatoa sp.
           PS|Rep: Secreted protein - Beggiatoa sp. PS
          Length = 853

 Score = 32.3 bits (70), Expect = 6.3
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
 Frame = +3

Query: 138 MAVVNAKKLKFSTLRGSFSETGINEFLRGLSFGRGQTAPVKGAE-----MPKITTTE-PW 299
           +A  NA  L F  +  SF+    NEFL  L +G       +GAE      PK+   + PW
Sbjct: 532 IASTNADTLTFQVIGNSFA----NEFLSLLEYGESLMGAFRGAEDVILNNPKLFAGQRPW 587

Query: 300 --DGNDGELPLEEDIDLSDVDLEKDEL 374
             D +DG+  L + +  +DV +E   L
Sbjct: 588 LDDDSDGQF-LNDGLRSADVYIETQRL 613


>UniRef50_A1VHJ4 Cluster: RND efflux system, outer membrane
           lipoprotein, NodT family precursor; n=2; Desulfovibrio
           vulgaris subsp. vulgaris|Rep: RND efflux system, outer
           membrane lipoprotein, NodT family precursor -
           Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
          Length = 504

 Score = 32.3 bits (70), Expect = 6.3
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
 Frame = +3

Query: 57  WGWIWAEAAAQPTLEEALELGGFGYPAMAVVNAKKLKFSTLRGSF---SETGINEFLRGL 227
           W  ++ +A      EEAL   G    AMA V+A + +  T+  S+   S TG    +R  
Sbjct: 50  WWTLFGDATLDALEEEALAANGDLATAMANVDASRAQL-TVATSYLLPSITGQGSSVRQR 108

Query: 228 SFGRGQTAPVKGAEM 272
              RGQ  PV+G E+
Sbjct: 109 GSERGQNPPVEGREV 123


>UniRef50_Q6C6T9 Cluster: Yarrowia lipolytica chromosome E of strain
           CLIB 122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome E of
           strain CLIB 122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 634

 Score = 32.3 bits (70), Expect = 6.3
 Identities = 13/29 (44%), Positives = 17/29 (58%)
 Frame = -3

Query: 139 MAG*PNPPSSKASSRVGCAAASAHIHPHI 53
           MAG P P +S A+S        AH+HPH+
Sbjct: 238 MAGQPPPGASAAASAANSLQTPAHVHPHV 266


>UniRef50_Q6UX30 Cluster: SAMK3000; n=1; Homo sapiens|Rep: SAMK3000
           - Homo sapiens (Human)
          Length = 100

 Score = 31.9 bits (69), Expect = 8.3
 Identities = 11/25 (44%), Positives = 18/25 (72%)
 Frame = +2

Query: 383 INSELCIVLHSVLCYVLCACVLTCR 457
           + + +C+ ++  +C VLCACV TCR
Sbjct: 26  VRAHVCVCVYMCMC-VLCACVCTCR 49


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 383,177,986
Number of Sequences: 1657284
Number of extensions: 6268274
Number of successful extensions: 23085
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 22059
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 22974
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 29691847201
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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