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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= I09A02NGRL0001_C18
         (399 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9VSU6 Cluster: CG4665-PA, isoform A; n=15; Bilateria|R...   188   3e-47
UniRef50_Q66IB5 Cluster: Zgc:112405; n=14; Euteleostomi|Rep: Zgc...   152   3e-36
UniRef50_P09417 Cluster: Dihydropteridine reductase; n=23; Eumet...   144   4e-34
UniRef50_Q8WTJ2 Cluster: Dihydropteridine reductase; n=3; Myceto...    91   6e-18
UniRef50_Q8I6Y4 Cluster: Quinonoid dihydropteridine reductase; n...    72   5e-12
UniRef50_UPI00006CC146 Cluster: hypothetical protein TTHERM_0022...    71   6e-12
UniRef50_A0DJ73 Cluster: Chromosome undetermined scaffold_52, wh...    68   8e-11
UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6...    43   0.002
UniRef50_Q1QXP0 Cluster: Short-chain dehydrogenase/reductase SDR...    42   0.003
UniRef50_A6C8E4 Cluster: UDP-glucose 4-epimerase; n=1; Planctomy...    40   0.018
UniRef50_UPI000050FF11 Cluster: COG0702: Predicted nucleoside-di...    37   0.17 
UniRef50_Q2CAE4 Cluster: Predicted dehydrogenase; n=1; Oceanicol...    36   0.39 
UniRef50_A6S8V0 Cluster: Putative uncharacterized protein; n=4; ...    36   0.39 
UniRef50_A6S0M5 Cluster: Putative uncharacterized protein; n=1; ...    36   0.39 
UniRef50_Q2U8H4 Cluster: Nucleoside-diphosphate-sugar epimerases...    35   0.51 
UniRef50_Q9HPP2 Cluster: Glucose 1-dehydrogenase; n=2; Halobacte...    35   0.67 
UniRef50_Q11WE7 Cluster: Sensor protein; n=1; Cytophaga hutchins...    34   0.89 
UniRef50_A3UGM6 Cluster: Oxidoreductase, short chain dehydrogena...    34   0.89 
UniRef50_Q2IKA0 Cluster: Short-chain dehydrogenase/reductase SDR...    33   1.6  
UniRef50_Q2AZB5 Cluster: Short-chain dehydrogenase/reductase SDR...    33   1.6  
UniRef50_A3VB77 Cluster: Possible FlgD protein; n=1; Rhodobacter...    33   1.6  
UniRef50_A3X572 Cluster: Short chain dehydrogenase; n=4; Rhodoba...    33   2.1  
UniRef50_Q2UQB0 Cluster: Predicted protein; n=1; Aspergillus ory...    33   2.1  
UniRef50_A7I972 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   2.1  
UniRef50_A4X1V9 Cluster: Short-chain dehydrogenase/reductase SDR...    33   2.7  
UniRef50_A4CHL2 Cluster: Putative uncharacterized protein; n=1; ...    33   2.7  
UniRef50_P52961 Cluster: GPI-linked NAD(P)(+)--arginine ADP-ribo...    33   2.7  
UniRef50_Q1GEJ9 Cluster: Short-chain dehydrogenase/reductase SDR...    32   3.6  
UniRef50_A5F9V2 Cluster: NAD-dependent epimerase/dehydratase; n=...    32   3.6  
UniRef50_A2C5Y7 Cluster: Dehydrogenases with different specifici...    32   4.8  
UniRef50_A4H827 Cluster: Putative uncharacterized protein; n=1; ...    32   4.8  
UniRef50_A5UW57 Cluster: Dehydrogenase-like protein; n=2; Roseif...    31   6.3  
UniRef50_A1SNH7 Cluster: Short-chain dehydrogenase/reductase SDR...    31   6.3  
UniRef50_Q97H04 Cluster: Flagellin; n=1; Clostridium acetobutyli...    31   8.3  
UniRef50_Q8D551 Cluster: Dehydrogenase; n=10; Vibrionales|Rep: D...    31   8.3  
UniRef50_Q3J6W6 Cluster: Lytic transglycosylase precursor; n=1; ...    31   8.3  
UniRef50_Q3WGG3 Cluster: Putative uncharacterized protein; n=1; ...    31   8.3  
UniRef50_Q0VP65 Cluster: Oxidoreductase; n=1; Alcanivorax borkum...    31   8.3  
UniRef50_Q0LN88 Cluster: Putative uncharacterized protein; n=1; ...    31   8.3  
UniRef50_Q6IJP9 Cluster: HDC14467; n=1; Drosophila melanogaster|...    31   8.3  
UniRef50_Q4QA60 Cluster: Putative uncharacterized protein; n=3; ...    31   8.3  

>UniRef50_Q9VSU6 Cluster: CG4665-PA, isoform A; n=15; Bilateria|Rep:
           CG4665-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 235

 Score =  188 bits (459), Expect = 3e-47
 Identities = 81/127 (63%), Positives = 110/127 (86%)
 Frame = +2

Query: 17  MTSGRIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHV 196
           M++GR++IYGG+GALGSACV+HFK++N+WV +IDL  NE AD ++ VP+DASWV+QE+ V
Sbjct: 1   MSAGRVVIYGGKGALGSACVDHFKANNYWVGSIDLTENEKADVSIVVPRDASWVEQEETV 60

Query: 197 VNELSNALQGQKVNAVICVAGGWAGGNAAKDLSKQADLMWRQSVWSSTIAATLAAKYLAP 376
           V+++  +L G+K++AVICVAGGWAGGNA KDL+K ADLMW+QSV +S I+A +AA++L  
Sbjct: 61  VSKVGESLAGEKLDAVICVAGGWAGGNAKKDLAKNADLMWKQSVLTSAISAAVAAQHLKA 120

Query: 377 GGLLALT 397
           GGLLALT
Sbjct: 121 GGLLALT 127


>UniRef50_Q66IB5 Cluster: Zgc:112405; n=14; Euteleostomi|Rep:
           Zgc:112405 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 239

 Score =  152 bits (368), Expect = 3e-36
 Identities = 69/123 (56%), Positives = 92/123 (74%), Gaps = 1/123 (0%)
 Frame = +2

Query: 29  RIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNEL 208
           ++I+YGG+GALGSACV +FK+ +WWVA+IDL+ NE A+ NV V    S+ +Q   V  ++
Sbjct: 8   KVIVYGGKGALGSACVQYFKAKHWWVASIDLSANEEANANVTVKMTESFTEQANQVTADV 67

Query: 209 SNALQGQKVNAVICVAGGWAGGNA-AKDLSKQADLMWRQSVWSSTIAATLAAKYLAPGGL 385
            + L  +KV+A+ CVAGGWAGG+A AK L K ADLMW+QSVW+STI + LA K+L  GGL
Sbjct: 68  GDLLGEEKVDAIFCVAGGWAGGSAKAKTLFKNADLMWKQSVWTSTICSHLATKHLREGGL 127

Query: 386 LAL 394
           L L
Sbjct: 128 LTL 130


>UniRef50_P09417 Cluster: Dihydropteridine reductase; n=23;
           Eumetazoa|Rep: Dihydropteridine reductase - Homo sapiens
           (Human)
          Length = 244

 Score =  144 bits (350), Expect = 4e-34
 Identities = 64/123 (52%), Positives = 88/123 (71%), Gaps = 1/123 (0%)
 Frame = +2

Query: 29  RIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNEL 208
           R+++YGGRGALGS CV  F++ NWWVA++D+  NE A  ++ V    S+ +Q   V  E+
Sbjct: 12  RVLVYGGRGALGSRCVQAFRARNWWVASVDVVENEEASASIIVKMTDSFTEQADQVTAEV 71

Query: 209 SNALQGQKVNAVICVAGGWAGGNA-AKDLSKQADLMWRQSVWSSTIAATLAAKYLAPGGL 385
              L  +KV+A++CVAGGWAGGNA +K L K  DLMW+QS+W+STI++ LA K+L  GGL
Sbjct: 72  GKLLGEEKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLATKHLKEGGL 131

Query: 386 LAL 394
           L L
Sbjct: 132 LTL 134


>UniRef50_Q8WTJ2 Cluster: Dihydropteridine reductase; n=3;
           Mycetozoa|Rep: Dihydropteridine reductase - Physarum
           polycephalum (Slime mold)
          Length = 231

 Score = 91.5 bits (217), Expect = 6e-18
 Identities = 46/124 (37%), Positives = 77/124 (62%), Gaps = 1/124 (0%)
 Frame = +2

Query: 29  RIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNEL 208
           R+++YGG GALG+A V+HFKS  W   ++D + + +A  +V +   +   +++ H V E 
Sbjct: 3   RVLVYGGNGALGNAVVSHFKSKGWDTISVDFSQSSNAAHSVVIEGSS---KEDVHKVIEG 59

Query: 209 SNALQGQKVNAVICVAGGWAGGNAAK-DLSKQADLMWRQSVWSSTIAATLAAKYLAPGGL 385
             A     ++A++CVAGGW GG+  + D+  + + MW+ +V SS  ++ +A+K L  GGL
Sbjct: 60  LKAKNIAALDALVCVAGGWQGGSIHEDDIFTKTERMWQFNVQSSIASSHVASKLLNEGGL 119

Query: 386 LALT 397
           L LT
Sbjct: 120 LVLT 123


>UniRef50_Q8I6Y4 Cluster: Quinonoid dihydropteridine reductase; n=7;
           Trypanosomatidae|Rep: Quinonoid dihydropteridine
           reductase - Leishmania major
          Length = 229

 Score = 71.7 bits (168), Expect = 5e-12
 Identities = 44/123 (35%), Positives = 64/123 (52%), Gaps = 1/123 (0%)
 Frame = +2

Query: 32  IIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNELS 211
           +++ G RGALG A  N F +  W + ++D                AS +++ Q       
Sbjct: 4   VLLIGARGALGRAVANAFANGKWSIISVDQAAAVQQGDECCAVNPASSIEELQQAYK--- 60

Query: 212 NALQGQKVNAVICVAGGWAGGNAA-KDLSKQADLMWRQSVWSSTIAATLAAKYLAPGGLL 388
           +A+ G KV+AVI VAGGWAGG+ A    +   +LM RQS++SS  AA + +      GLL
Sbjct: 61  SAVTGLKVDAVINVAGGWAGGSVADASTAASTELMLRQSLFSSVAAAHVFSTQGEKNGLL 120

Query: 389 ALT 397
            LT
Sbjct: 121 LLT 123


>UniRef50_UPI00006CC146 Cluster: hypothetical protein
           TTHERM_00220710; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00220710 - Tetrahymena
           thermophila SB210
          Length = 233

 Score = 71.3 bits (167), Expect = 6e-12
 Identities = 45/129 (34%), Positives = 71/129 (55%), Gaps = 2/129 (1%)
 Frame = +2

Query: 17  MTSGR-IIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQH 193
           M S R +++ GG G LG + ++ FKS NW +A+I LN N  ++ N+ +P++ S  Q    
Sbjct: 1   MASQRTLLVIGGCGNLGRSVISKFKS-NWNIASIGLNINNESNKNIILPQNQSASQYVSE 59

Query: 194 VVNELSNALQGQKVNAVICVAGGWAGGNAA-KDLSKQADLMWRQSVWSSTIAATLAAKYL 370
           V  +L +       +A+ICVAGGW GG+    ++ +    M   +V  S +AA L+  +L
Sbjct: 60  VKQQLKSF--SPSYDAIICVAGGWNGGSIKDSNVFETYHKMHSVNVIPSILAAHLSTHFL 117

Query: 371 APGGLLALT 397
              GLL  T
Sbjct: 118 RKNGLLVFT 126


>UniRef50_A0DJ73 Cluster: Chromosome undetermined scaffold_52, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_52,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 222

 Score = 67.7 bits (158), Expect = 8e-11
 Identities = 44/124 (35%), Positives = 69/124 (55%), Gaps = 1/124 (0%)
 Frame = +2

Query: 29  RIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNEL 208
           + +I+GG GALG + V  FK   W V ++D N NE  D N+ + K+AS +   +  +N L
Sbjct: 2   KALIFGGSGALGRSMVKVFKG--WKVTSVDFNKNEECD-NIII-KNASDINLLKSELNTL 57

Query: 209 SNALQGQKVNAVICVAGGWAGGNAAKDLSKQA-DLMWRQSVWSSTIAATLAAKYLAPGGL 385
                 +K N ++CVAGGW GG+  ++   Q  + M ++SV  + + + LA   L+  GL
Sbjct: 58  ------EKFNCIVCVAGGWTGGSIKEENVLQVYEDMNQKSVVPALVCSHLATTQLSRQGL 111

Query: 386 LALT 397
           L  T
Sbjct: 112 LIFT 115


>UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6;
           Pseudomonas aeruginosa|Rep: Probable short-chain
           dehydrogenase - Pseudomonas aeruginosa
          Length = 252

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 4/122 (3%)
 Frame = +2

Query: 17  MTSGRIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHV 196
           M++  ++I G  G LG A    F  S+W +A  D++       N  VP DAS V   +  
Sbjct: 1   MSTPVVLITGAAGGLGRAIAKRFAQSHWRIAATDVDKEGLHALNAQVPLDASGVADLRSA 60

Query: 197 VN---ELSNAL-QGQKVNAVICVAGGWAGGNAAKDLSKQADLMWRQSVWSSTIAATLAAK 364
            N    +S  L +  +++A++  AG W  G       +  DL+   ++ +S      A  
Sbjct: 61  DNCHTLMSKILARTGRLDALVNAAGVWREGPVENFTEEDFDLVLGVNLKASFYMCQAAIP 120

Query: 365 YL 370
           YL
Sbjct: 121 YL 122


>UniRef50_Q1QXP0 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Chromohalobacter salexigens DSM
           3043|Rep: Short-chain dehydrogenase/reductase SDR
           precursor - Chromohalobacter salexigens (strain DSM 3043
           / ATCC BAA-138 / NCIMB13768)
          Length = 233

 Score = 42.3 bits (95), Expect = 0.003
 Identities = 28/121 (23%), Positives = 54/121 (44%)
 Frame = +2

Query: 32  IIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNELS 211
           +I+ G    +G AC   F    W V  +D  P +  D    VP  A+ +  EQ V   + 
Sbjct: 9   VIVTGSASGMGQACAQRFLDEGWRVIALDTQP-QLTDHTRLVPVQAN-ICDEQQVAEVID 66

Query: 212 NALQGQKVNAVICVAGGWAGGNAAKDLSKQADLMWRQSVWSSTIAATLAAKYLAPGGLLA 391
           +A+  + V+A++  AG +   N      +    ++  +V  +     +A++++  GG + 
Sbjct: 67  HAVGDKPVSALVHAAGVFPTSNLETFDEESYRRIFDVNVLGTLNITRVASEHMHHGGSMM 126

Query: 392 L 394
           L
Sbjct: 127 L 127


>UniRef50_A6C8E4 Cluster: UDP-glucose 4-epimerase; n=1; Planctomyces
           maris DSM 8797|Rep: UDP-glucose 4-epimerase -
           Planctomyces maris DSM 8797
          Length = 345

 Score = 39.9 bits (89), Expect = 0.018
 Identities = 24/72 (33%), Positives = 37/72 (51%)
 Frame = +2

Query: 32  IIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNELS 211
           I++ GG G +GS CV    ++   V  ID   N S     AVP  AS+ Q +    +EL 
Sbjct: 3   ILVTGGAGYIGSHCVQQLLAAGQKVCVID---NLSRGHREAVPSQASFFQLDLGETDELI 59

Query: 212 NALQGQKVNAVI 247
           + ++ Q++  VI
Sbjct: 60  DVMKSQRIEKVI 71


>UniRef50_UPI000050FF11 Cluster: COG0702: Predicted
           nucleoside-diphosphate-sugar epimerases; n=1;
           Brevibacterium linens BL2|Rep: COG0702: Predicted
           nucleoside-diphosphate-sugar epimerases - Brevibacterium
           linens BL2
          Length = 228

 Score = 36.7 bits (81), Expect = 0.17
 Identities = 28/94 (29%), Positives = 46/94 (48%)
 Frame = +2

Query: 29  RIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNEL 208
           R++I GG G +       FK + + V ++  NP++SA+   A   +A  +  E    ++L
Sbjct: 6   RVVILGGHGKIALMAAPKFKEAGYSVDSVIRNPDQSAEVE-AAGANAVVLDIESAETDKL 64

Query: 209 SNALQGQKVNAVICVAGGWAGGNAAKDLSKQADL 310
           +    G K  AV+  AG   GGN   D ++  DL
Sbjct: 65  AELFTGAK--AVVFSAGA-GGGN--PDRTRAVDL 93


>UniRef50_Q2CAE4 Cluster: Predicted dehydrogenase; n=1; Oceanicola
           granulosus HTCC2516|Rep: Predicted dehydrogenase -
           Oceanicola granulosus HTCC2516
          Length = 241

 Score = 35.5 bits (78), Expect = 0.39
 Identities = 14/35 (40%), Positives = 19/35 (54%)
 Frame = +2

Query: 23  SGRIIIYGGRGALGSACVNHFKSSNWWVANIDLNP 127
           SG ++I G  G +G+A   HF    W V  +DL P
Sbjct: 2   SGHVLITGAAGGIGAALAAHFAGRGWTVTALDLAP 36


>UniRef50_A6S8V0 Cluster: Putative uncharacterized protein; n=4;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 304

 Score = 35.5 bits (78), Expect = 0.39
 Identities = 21/76 (27%), Positives = 36/76 (47%)
 Frame = +2

Query: 32  IIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNELS 211
           + I G  GALG   +     SN +  NI +    S+      P  A+ +  + +    L+
Sbjct: 7   VAIAGSNGALGKPILEALLQSNKF--NITILTRSSSTSTSTYPSSATVLPVDFNSTQSLT 64

Query: 212 NALQGQKVNAVICVAG 259
           +ALQ QK++A++   G
Sbjct: 65  DALQSQKIDAIVSCVG 80


>UniRef50_A6S0M5 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 263

 Score = 35.5 bits (78), Expect = 0.39
 Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 6/101 (5%)
 Frame = +2

Query: 17  MTSGRIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPK-----DASWVQ 181
           M S R++I+GG G +G   V+   + +W V ++  +  + AD     PK     D     
Sbjct: 1   MASLRVLIFGGNGGIGQLIVDSMLTRSWHVTSVIRDSRQKADALRLGPKKGPKADILVCD 60

Query: 182 QEQHVVNELSNALQGQKVNAVICVAGGWAGGNAA-KDLSKQ 301
             +    + S  L   K N V+  AG     NA  +D +K+
Sbjct: 61  LARMKDEDASKILTQVKPNYVVFAAGSMTNVNAVDRDAAKK 101


>UniRef50_Q2U8H4 Cluster: Nucleoside-diphosphate-sugar epimerases;
           n=6; Pezizomycotina|Rep: Nucleoside-diphosphate-sugar
           epimerases - Aspergillus oryzae
          Length = 306

 Score = 35.1 bits (77), Expect = 0.51
 Identities = 14/35 (40%), Positives = 21/35 (60%)
 Frame = +2

Query: 23  SGRIIIYGGRGALGSACVNHFKSSNWWVANIDLNP 127
           S RII+ GG G  G   ++H  +  + + N+DLNP
Sbjct: 2   SKRIIVTGGSGKAGQYVIHHLLAQGYSILNLDLNP 36


>UniRef50_Q9HPP2 Cluster: Glucose 1-dehydrogenase; n=2;
           Halobacteriaceae|Rep: Glucose 1-dehydrogenase -
           Halobacterium salinarium (Halobacterium halobium)
          Length = 236

 Score = 34.7 bits (76), Expect = 0.67
 Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
 Frame = +2

Query: 32  IIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQ-------QEQ 190
           +++ G  GALGSA    F  +   V   D+     +D  V  P  AS+ Q       Q  
Sbjct: 12  VLVTGAVGALGSAVCRAFADAGATVCGTDVVAPAESDDAVPTPTFASFYQGDLTEDTQAA 71

Query: 191 HVVNELSNALQGQKVNAVICVAGGWAGGN 277
           HVV+  S       ++A+  VAG W GG+
Sbjct: 72  HVVS--STVADHGGLDALCNVAGMWQGGD 98


>UniRef50_Q11WE7 Cluster: Sensor protein; n=1; Cytophaga
           hutchinsonii ATCC 33406|Rep: Sensor protein - Cytophaga
           hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 696

 Score = 34.3 bits (75), Expect = 0.89
 Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
 Frame = -3

Query: 226 TLQSVT*FVDYMLLLLYPRGIFRHGNVEISTFIWV-KVYIC 107
           TLQ +T F+  ++ +LY  GI R GN   S FIW   +Y+C
Sbjct: 320 TLQ-MTAFLQIIIYILYGLGIRRKGNANASYFIWAWSLYLC 359


>UniRef50_A3UGM6 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=2;
           Hyphomonadaceae|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Oceanicaulis
           alexandrii HTCC2633
          Length = 264

 Score = 34.3 bits (75), Expect = 0.89
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 12/129 (9%)
 Frame = +2

Query: 23  SGRI-IIYGGRGALGSACVNHFKSSNWWVANIDLNPNESA----DF-----NVAVPKDAS 172
           +G+I I+ GG   +G AC + F +    V   DLN + +A    +F      V V  +A+
Sbjct: 4   NGKIAIVTGGASGIGKACASAFHAQGARVVIADLNTDAAARAGSEFGGFGQGVDVTDEAA 63

Query: 173 WVQQEQHVVNELSNALQGQKVNAVICVAGG--WAGGNAAKDLSKQADLMWRQSVWSSTIA 346
             +    V  EL   +     NA I V+ G  W  G+A    +   D  W+ +V +S  A
Sbjct: 64  LARLINRVEREL-GPVDIFMSNAGIGVSDGPLWGAGDAP---TPAWDACWQVNVMASVYA 119

Query: 347 ATLAAKYLA 373
           A + AK +A
Sbjct: 120 ARMLAKSMA 128


>UniRef50_Q2IKA0 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Anaeromyxobacter dehalogenans 2CP-C|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 236

 Score = 33.5 bits (73), Expect = 1.6
 Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
 Frame = +2

Query: 32  IIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASW----VQQEQHVV 199
           I+I G  GALG+A   H  +  + VA + L  +E     +     A +    ++ +    
Sbjct: 5   IVISGAVGALGTALAGHLVAHGYRVAGVGLRRHEERLRTLEADLGAGFAGFTLEADSTAA 64

Query: 200 NELSNALQGQKVNAV---ICVAGGWAGGNAAKDLSKQADLMWRQSVWSSTIAATLAAKYL 370
            + +    G ++ AV     VAGGW GG    +   + +  WR  +  +  +A  A + L
Sbjct: 65  WDATLDAVGSRLGAVSGAALVAGGWRGGEPFHE--DRDEGTWRSMLDENLESAQRALRAL 122

Query: 371 AP 376
            P
Sbjct: 123 MP 124


>UniRef50_Q2AZB5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacillus cereus group|Rep: Short-chain
           dehydrogenase/reductase SDR - Bacillus
           weihenstephanensis KBAB4
          Length = 248

 Score = 33.5 bits (73), Expect = 1.6
 Identities = 17/61 (27%), Positives = 31/61 (50%)
 Frame = +2

Query: 32  IIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNELS 211
           I+I G    +G+AC+ +F   ++ V  +D+N N+  D+          VQ +    NE++
Sbjct: 7   IMISGANSGIGNACIEYFLEKSFNVIALDINTNKLVDY-TKTHTSFKLVQIDLSNSNEIN 65

Query: 212 N 214
           N
Sbjct: 66  N 66


>UniRef50_A3VB77 Cluster: Possible FlgD protein; n=1;
           Rhodobacterales bacterium HTCC2654|Rep: Possible FlgD
           protein - Rhodobacterales bacterium HTCC2654
          Length = 227

 Score = 33.5 bits (73), Expect = 1.6
 Identities = 23/64 (35%), Positives = 31/64 (48%)
 Frame = +2

Query: 119 LNPNESADFNVAVPKDASWVQQEQHVVNELSNALQGQKVNAVICVAGGWAGGNAAKDLSK 298
           LNP ES+D+ V +   +   QQ Q   N+L  ALQ Q     +    GW G  A   +S 
Sbjct: 52  LNPIESSDYAVQLATFSGVEQQVQ--TNDLLKALQTQLGVMSMSDLAGWVGMEARAGVSA 109

Query: 299 QADL 310
           Q D+
Sbjct: 110 QFDM 113


>UniRef50_A3X572 Cluster: Short chain dehydrogenase; n=4;
           Rhodobacterales|Rep: Short chain dehydrogenase -
           Roseobacter sp. MED193
          Length = 256

 Score = 33.1 bits (72), Expect = 2.1
 Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 4/120 (3%)
 Frame = +2

Query: 29  RIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQE---QHVV 199
           R++I  G   +G A    F ++ + V   DL+P+  A+         +    E   Q + 
Sbjct: 7   RVLITAGGSGIGRAMAEGFAAAGFKVWITDLDPDTVANLPPGWRGTVANAADEVSVQALF 66

Query: 200 NELSNALQGQKVNAVICVAGGWAGGNA-AKDLSKQADLMWRQSVWSSTIAATLAAKYLAP 376
           +E++    G +V   +C   G AG  A  +D++ Q    WR  V  +   A LAAKY  P
Sbjct: 67  DEIAEQWGGLEV---LCANAGIAGPTALVEDVALQD---WRACVSVNLEGAFLAAKYATP 120


>UniRef50_Q2UQB0 Cluster: Predicted protein; n=1; Aspergillus
           oryzae|Rep: Predicted protein - Aspergillus oryzae
          Length = 159

 Score = 33.1 bits (72), Expect = 2.1
 Identities = 15/31 (48%), Positives = 21/31 (67%)
 Frame = -2

Query: 389 QVIHPAPSILQLMWLRLSNSRPIAATSSLPA 297
           +VI  AP++LQL WL L+ S+P    S LP+
Sbjct: 122 RVIGNAPAVLQLYWLLLARSKPRFRISQLPS 152


>UniRef50_A7I972 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Candidatus Methanoregula boonei 6A8|Rep: NAD-dependent
           epimerase/dehydratase - Methanoregula boonei (strain
           6A8)
          Length = 369

 Score = 33.1 bits (72), Expect = 2.1
 Identities = 13/29 (44%), Positives = 16/29 (55%)
 Frame = +2

Query: 32  IIIYGGRGALGSACVNHFKSSNWWVANID 118
           +II G  G +GSACV  F    W V  +D
Sbjct: 4   VIITGSSGLIGSACVEKFLHEGWHVTGVD 32


>UniRef50_A4X1V9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR - Salinispora tropica
           CNB-440
          Length = 280

 Score = 32.7 bits (71), Expect = 2.7
 Identities = 26/75 (34%), Positives = 39/75 (52%)
 Frame = +2

Query: 152 AVPKDASWVQQEQHVVNELSNALQGQKVNAVICVAGGWAGGNAAKDLSKQADLMWRQSVW 331
           AV  D +  QQ   VV     A+ G+ V+AV+  AGG+ GG     L+  A+  WR S+ 
Sbjct: 91  AVVADLTDPQQVPRVVE----AVDGRAVDAVVNNAGGYLGGE-PDTLAGVAE-QWRASLE 144

Query: 332 SSTIAATLAAKYLAP 376
           ++ + A L  + L P
Sbjct: 145 ANLLTAVLLTEALRP 159


>UniRef50_A4CHL2 Cluster: Putative uncharacterized protein; n=1;
           Robiginitalea biformata HTCC2501|Rep: Putative
           uncharacterized protein - Robiginitalea biformata
           HTCC2501
          Length = 198

 Score = 32.7 bits (71), Expect = 2.7
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = +2

Query: 26  GRIIIYGGRGALGSACVNHFKSSNWWVANIDL 121
           GRI+I GG G + SAC+N+   S  WV  + +
Sbjct: 144 GRILIIGGVGYVLSACINYAGISGSWVGTLTI 175


>UniRef50_P52961 Cluster: GPI-linked NAD(P)(+)--arginine
           ADP-ribosyltransferase 1 precursor (EC 2.4.2.31)
           (Mono(ADP-ribosyl)transferase); n=18; Eutheria|Rep:
           GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
           precursor (EC 2.4.2.31) (Mono(ADP-ribosyl)transferase) -
           Homo sapiens (Human)
          Length = 327

 Score = 32.7 bits (71), Expect = 2.7
 Identities = 13/22 (59%), Positives = 16/22 (72%)
 Frame = -3

Query: 103 PPVGRFKVINASRPQRAPAAVY 38
           PP   F+VINASRP + PA +Y
Sbjct: 244 PPFETFQVINASRPAQGPARIY 265


>UniRef50_Q1GEJ9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Silicibacter sp. (strain
           TM1040)
          Length = 250

 Score = 32.3 bits (70), Expect = 3.6
 Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 7/123 (5%)
 Frame = +2

Query: 29  RIIIYGGRGALGSACVNHFKSSNW--WVANIDLNPNESADFNVAVPKDASWVQQEQHVVN 202
           R+++  G   +G A    F ++    WV+++D       D   A+P    W  ++    +
Sbjct: 2   RVLVTAGASGIGRAMAEGFVATGAEVWVSDVD------RDALAALPD--GWNARQVDATD 53

Query: 203 ELS-NALQGQKVNA----VICVAGGWAGGNAAKDLSKQADLMWRQSVWSSTIAATLAAKY 367
           E++  AL  +   A    V+C   G AG  A  +  +  D  WR  V  +   A LAAKY
Sbjct: 54  EVAMRALFAEIAQAGGLDVLCANAGVAGPTALVEDIQLED--WRACVSVNLEGAFLAAKY 111

Query: 368 LAP 376
            AP
Sbjct: 112 AAP 114


>UniRef50_A5F9V2 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Flavobacterium johnsoniae UW101
          Length = 213

 Score = 32.3 bits (70), Expect = 3.6
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
 Frame = +2

Query: 29  RIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNEL 208
           +I I G  G +GSA +N        +  I  NP ++A        + +W   +   VNEL
Sbjct: 2   KIAIIGATGFVGSAILNELADRKHDITAIARNPKDTA--------NVTWKSADIFNVNEL 53

Query: 209 SNALQGQKVNAVI-CVAGGWAGGNAAKD 289
           +  L+G   +AVI     GW   N   D
Sbjct: 54  AEILKGN--DAVINAYNSGWTNPNIYDD 79


>UniRef50_A2C5Y7 Cluster: Dehydrogenases with different
           specificities; n=1; Prochlorococcus marinus str. MIT
           9303|Rep: Dehydrogenases with different specificities -
           Prochlorococcus marinus (strain MIT 9303)
          Length = 231

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 3/126 (2%)
 Frame = +2

Query: 23  SGRIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVN 202
           SG  +++G RGALGS      K  ++ V      P+++ + ++ V       Q+ Q    
Sbjct: 2   SGNALLFGSRGALGSEIEKVMKQKSFRVLTAGSGPDDAINNHLQVA-----YQRPQ---- 52

Query: 203 ELSNALQGQKVNAVICVAGGWAGGNAAKDLSKQADLMWRQSVWSST---IAATLAAKYLA 373
           E S+      ++ VI     WA G    D+    DL   + +W S    IA++L+A  L 
Sbjct: 53  EASDFYSLPSLDVVI-----WAHGLNCSDVIADFDLEDLERLWQSNVVFIASSLSA-LLK 106

Query: 374 PGGLLA 391
            G LLA
Sbjct: 107 AGKLLA 112


>UniRef50_A4H827 Cluster: Putative uncharacterized protein; n=1;
           Leishmania braziliensis|Rep: Putative uncharacterized
           protein - Leishmania braziliensis
          Length = 1741

 Score = 31.9 bits (69), Expect = 4.8
 Identities = 16/45 (35%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
 Frame = +2

Query: 269 GGNAAKDLSKQADLMWRQSVW-SSTIAATLAAKYLAP-GGLLALT 397
           GG    D  + +DL+WR+ +W  + ++A+   K+L P GG+ A T
Sbjct: 404 GGTPVADGRRSSDLLWRKELWRGAGMSASSDPKHLEPDGGIHAST 448


>UniRef50_A5UW57 Cluster: Dehydrogenase-like protein; n=2;
           Roseiflexus|Rep: Dehydrogenase-like protein -
           Roseiflexus sp. RS-1
          Length = 728

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 13/50 (26%), Positives = 26/50 (52%)
 Frame = +2

Query: 17  MTSGRIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKD 166
           ++ GRI++ G  G++GSAC      +   VA + + P +  D    + ++
Sbjct: 456 LSRGRIMVIGATGSIGSACARLAAQATKDVALVSIEPEKLIDLKRLIERE 505


>UniRef50_A1SNH7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 272

 Score = 31.5 bits (68), Expect = 6.3
 Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 6/123 (4%)
 Frame = +2

Query: 26  GRIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADF-----NVAVPKDASWVQQEQ 190
           G ++   GRG +G A      +    V   DL+P  +         VAVP DAS      
Sbjct: 9   GVVVTGAGRG-IGRALARRLAAEGARVVVNDLDPASAEAVAAEVGGVAVPGDASSADGVA 67

Query: 191 HVVNELSNALQGQKVNAVICVAG-GWAGGNAAKDLSKQADLMWRQSVWSSTIAATLAAKY 367
            +V   + AL   +++     AG   AGG    D  + +D  W++ +  + +A   AA+ 
Sbjct: 68  ALVERATEALG--RIDVYCANAGIDGAGGLGGVDSLQTSDEHWQRILEVNVLAHVRAARL 125

Query: 368 LAP 376
           L P
Sbjct: 126 LVP 128


>UniRef50_Q97H04 Cluster: Flagellin; n=1; Clostridium
           acetobutylicum|Rep: Flagellin - Clostridium
           acetobutylicum
          Length = 425

 Score = 31.1 bits (67), Expect = 8.3
 Identities = 22/90 (24%), Positives = 44/90 (48%)
 Frame = +2

Query: 110 NIDLNPNESADFNVAVPKDASWVQQEQHVVNELSNALQGQKVNAVICVAGGWAGGNAAKD 289
           N D++ N  + +N  +     W+ Q    +N+  N +  Q++  ++  AG        +D
Sbjct: 53  NTDISIN--SQYNTNINNTIYWLNQTDTALNQAGNIV--QRIKELLISAGNGGYTQDQRD 108

Query: 290 LSKQADLMWRQSVWSSTIAATLAAKYLAPG 379
            S +A+L  R S +S+ I ++ + +YL  G
Sbjct: 109 -SIKAELNQRISEFSNVINSSFSGQYLFGG 137


>UniRef50_Q8D551 Cluster: Dehydrogenase; n=10; Vibrionales|Rep:
           Dehydrogenase - Vibrio vulnificus
          Length = 223

 Score = 31.1 bits (67), Expect = 8.3
 Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
 Frame = +2

Query: 242 VICVAGGWAGGNAAKDLS-KQADLMWRQSVWSSTIAATLAAKYLAPGGLLALT 397
           +I  AG +A      D+   QA   +    W + +AA   A+YL  GG + LT
Sbjct: 63  LIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVLAAKHGARYLKQGGSITLT 115


>UniRef50_Q3J6W6 Cluster: Lytic transglycosylase precursor; n=1;
           Nitrosococcus oceani ATCC 19707|Rep: Lytic
           transglycosylase precursor - Nitrosococcus oceani
           (strain ATCC 19707 / NCIMB 11848)
          Length = 503

 Score = 31.1 bits (67), Expect = 8.3
 Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
 Frame = -2

Query: 326 PIAATSSLPAYSGPWQRF--RLPNHQRRK*Q-HSLSDLAKRYLV 204
           P  + S + AY  PW+RF  ++PN   +  Q  +LS +A+RY +
Sbjct: 366 PTCSRSKVLAYLAPWERFEKQIPNRFHKVQQGQTLSHIARRYRI 409


>UniRef50_Q3WGG3 Cluster: Putative uncharacterized protein; n=1;
           Frankia sp. EAN1pec|Rep: Putative uncharacterized
           protein - Frankia sp. EAN1pec
          Length = 306

 Score = 31.1 bits (67), Expect = 8.3
 Identities = 18/70 (25%), Positives = 31/70 (44%)
 Frame = +2

Query: 17  MTSGRIIIYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHV 196
           M+  RI++ G  G  G A   H  ++ W V  +  +P   A       + A  V+ E   
Sbjct: 1   MSGQRIVVVGATGLQGRAVTAHLLAAGWRVRAMTRDPG-GAPARALAAEGAEIVRGEMDD 59

Query: 197 VNELSNALQG 226
           ++ L+ A+ G
Sbjct: 60  IDSLTAAMHG 69


>UniRef50_Q0VP65 Cluster: Oxidoreductase; n=1; Alcanivorax
           borkumensis SK2|Rep: Oxidoreductase - Alcanivorax
           borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
          Length = 327

 Score = 31.1 bits (67), Expect = 8.3
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 3/84 (3%)
 Frame = +2

Query: 38  IYGGRGALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNELSNA 217
           I GGRG LG   ++      W V  + + PN  A   +   K  S VQ       EL+  
Sbjct: 6   ISGGRGFLGGHIIDQLLDKQWEVVAL-VRPNSDAS-ALQAKKGVSVVQAPLDNATELALV 63

Query: 218 LQGQKVNAVICVAGG---WAGGNA 280
           +     +AV  VAG    W  GNA
Sbjct: 64  MPAAP-DAVFHVAGNTSLWRRGNA 86


>UniRef50_Q0LN88 Cluster: Putative uncharacterized protein; n=1;
           Herpetosiphon aurantiacus ATCC 23779|Rep: Putative
           uncharacterized protein - Herpetosiphon aurantiacus ATCC
           23779
          Length = 133

 Score = 31.1 bits (67), Expect = 8.3
 Identities = 16/43 (37%), Positives = 24/43 (55%)
 Frame = +3

Query: 66  LLALITLNLPTGGSQI*TLTQMKVLISTLPCLKMPRGYNRSNM 194
           +LAL  +NLPT  S+    T+ K   +T+PC K     +R N+
Sbjct: 13  VLALKNMNLPTKLSRKLLTTRRKATAATIPCFKRGNRGSRGNL 55


>UniRef50_Q6IJP9 Cluster: HDC14467; n=1; Drosophila
           melanogaster|Rep: HDC14467 - Drosophila melanogaster
           (Fruit fly)
          Length = 345

 Score = 31.1 bits (67), Expect = 8.3
 Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 3/44 (6%)
 Frame = +2

Query: 260 GWAGGNAAKDLSKQADLMWRQSVWSSTIAATLA---AKYLAPGG 382
           G AG   AK LS +   +W  S W+S++AAT +   A+++ PGG
Sbjct: 192 GHAGPPGAKTLSPE---VWPSSSWTSSMAATSSGEIARHVGPGG 232


>UniRef50_Q4QA60 Cluster: Putative uncharacterized protein; n=3;
            Leishmania|Rep: Putative uncharacterized protein -
            Leishmania major
          Length = 874

 Score = 31.1 bits (67), Expect = 8.3
 Identities = 26/123 (21%), Positives = 51/123 (41%), Gaps = 2/123 (1%)
 Frame = +2

Query: 32   IIIYGGRG--ALGSACVNHFKSSNWWVANIDLNPNESADFNVAVPKDASWVQQEQHVVNE 205
            ++ Y GR   A  SA  +  +  NW +A+I     +     +A P++ +   +   +V+ 
Sbjct: 690  LVEYSGRAERAAASALPSSHQQPNWVMADITYEEFKWILETIAGPREIARAARLLRLVSV 749

Query: 206  LSNALQGQKVNAVICVAGGWAGGNAAKDLSKQADLMWRQSVWSSTIAATLAAKYLAPGGL 385
            +        +   IC  GG+ GG+ A  ++ +A        W        + +YL   G 
Sbjct: 750  VDTTF----LRHHICSGGGYEGGDGAPSVTGRATAAPHSCPWPPPPPIFTSVEYLRLSGK 805

Query: 386  LAL 394
            ++L
Sbjct: 806  VSL 808


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 436,927,134
Number of Sequences: 1657284
Number of extensions: 8447989
Number of successful extensions: 26673
Number of sequences better than 10.0: 41
Number of HSP's better than 10.0 without gapping: 26052
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 26660
length of database: 575,637,011
effective HSP length: 92
effective length of database: 423,166,883
effective search space used: 16926675320
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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