Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP03_T7_G08
(791 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 ... 187 5e-47
J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide acetyltr... 187 5e-47
BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide S-acet... 187 5e-47
AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide S-acet... 187 5e-47
Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein. 144 3e-34
U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase co... 144 3e-34
U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl tr... 144 3e-34
AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing compo... 144 3e-34
AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide dehydr... 144 3e-34
BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase ... 144 4e-34
X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide S-acetyl... 92 2e-18
D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial dihydrolipo... 90 1e-17
L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide succinyl... 89 1e-17
D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide succinyl... 89 1e-17
CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein. 89 1e-17
BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide S-succ... 89 1e-17
BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide S-succ... 89 1e-17
AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein. 89 1e-17
S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate dehyd... 77 1e-13
X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein. 76 1e-13
J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched ... 76 1e-13
BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branch... 76 1e-13
BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branch... 76 1e-13
M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylas... 74 7e-13
AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branch... 74 7e-13
AM260536-1|CAJ97431.1| 1266|Homo sapiens ponsin protein. 31 6.3
AL158165-8|CAI14385.1| 1004|Homo sapiens sorbin and SH3 domain c... 31 6.3
AL158165-7|CAI14379.1| 1292|Homo sapiens sorbin and SH3 domain c... 31 6.3
AL158165-6|CAI14380.1| 811|Homo sapiens sorbin and SH3 domain c... 31 6.3
AL158165-5|CAI14381.1| 1151|Homo sapiens sorbin and SH3 domain c... 31 6.3
AL158165-2|CAI14383.1| 905|Homo sapiens sorbin and SH3 domain c... 31 6.3
AJ489942-1|CAD34588.1| 846|Homo sapiens c-Cbl associated protei... 31 6.3
AF356527-1|AAK37565.1| 905|Homo sapiens sorbin and SH3 domain c... 31 6.3
AF356526-1|AAK37564.1| 1151|Homo sapiens sorbin and SH3 domain c... 31 6.3
AF356525-1|AAK37563.1| 1292|Homo sapiens sorbin and SH3 domain c... 31 6.3
AF330623-1|AAK57479.1| 811|Homo sapiens brain R85FL protein. 31 6.3
AF136381-1|AAF22175.1| 1004|Homo sapiens c-Cbl-associated protei... 31 6.3
>Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 to
561) protein.
Length = 615
Score = 187 bits (455), Expect = 5e-47
Identities = 88/156 (56%), Positives = 116/156 (74%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIKA A AC +VP NS WM++ IRQ VDVSVAV+TP GLITPI+ NA +G+ +
Sbjct: 446 DFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETI 505
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQELV 267
+ ++ LA KA++GKLQP E+QGGT T+SNLGM+GI F+AIINPPQ+ I+A G ++ +
Sbjct: 506 ANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKL 565
Query: 266 IPDQSEPNGFRTAKFVTFTASADHRVVDGAIGAQWM 159
+P +E GF A ++ T S DHRVVDGA+GAQW+
Sbjct: 566 VPADNE-KGFDVASMMSVTLSCDHRVVDGAVGAQWL 600
>J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide
acetyltransferase protein.
Length = 613
Score = 187 bits (455), Expect = 5e-47
Identities = 88/156 (56%), Positives = 116/156 (74%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIKA A AC +VP NS WM++ IRQ VDVSVAV+TP GLITPI+ NA +G+ +
Sbjct: 444 DFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETI 503
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQELV 267
+ ++ LA KA++GKLQP E+QGGT T+SNLGM+GI F+AIINPPQ+ I+A G ++ +
Sbjct: 504 ANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKL 563
Query: 266 IPDQSEPNGFRTAKFVTFTASADHRVVDGAIGAQWM 159
+P +E GF A ++ T S DHRVVDGA+GAQW+
Sbjct: 564 VPADNE-KGFDVASMMSVTLSCDHRVVDGAVGAQWL 598
>BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 187 bits (455), Expect = 5e-47
Identities = 88/156 (56%), Positives = 116/156 (74%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIKA A AC +VP NS WM++ IRQ VDVSVAV+TP GLITPI+ NA +G+ +
Sbjct: 478 DFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETI 537
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQELV 267
+ ++ LA KA++GKLQP E+QGGT T+SNLGM+GI F+AIINPPQ+ I+A G ++ +
Sbjct: 538 ANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKL 597
Query: 266 IPDQSEPNGFRTAKFVTFTASADHRVVDGAIGAQWM 159
+P +E GF A ++ T S DHRVVDGA+GAQW+
Sbjct: 598 VPADNE-KGFDVASMMSVTLSCDHRVVDGAVGAQWL 632
>AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 187 bits (455), Expect = 5e-47
Identities = 88/156 (56%), Positives = 116/156 (74%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIKA A AC +VP NS WM++ IRQ VDVSVAV+TP GLITPI+ NA +G+ +
Sbjct: 478 DFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETI 537
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQELV 267
+ ++ LA KA++GKLQP E+QGGT T+SNLGM+GI F+AIINPPQ+ I+A G ++ +
Sbjct: 538 ANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKL 597
Query: 266 IPDQSEPNGFRTAKFVTFTASADHRVVDGAIGAQWM 159
+P +E GF A ++ T S DHRVVDGA+GAQW+
Sbjct: 598 VPADNE-KGFDVASMMSVTLSCDHRVVDGAVGAQWL 632
>Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein.
Length = 501
Score = 144 bits (349), Expect = 3e-34
Identities = 71/159 (44%), Positives = 108/159 (67%), Gaps = 2/159 (1%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIKA A K++P VN W +Q +D+SVAVAT GL+TPI+ +A ++GI ++
Sbjct: 330 DFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEI 389
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQE-L 270
+ ++K L++KA+DGKL P+EYQGG+ ++SNLGM+GI F A+INPPQ+ I+A G + L
Sbjct: 390 ADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVL 449
Query: 269 VIPDQSEPNG-FRTAKFVTFTASADHRVVDGAIGAQWMK 156
+ + E N + + +T T S+D RVVD + +++K
Sbjct: 450 KLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLK 488
>U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase
complex protein X subunit precursor protein.
Length = 501
Score = 144 bits (349), Expect = 3e-34
Identities = 71/159 (44%), Positives = 108/159 (67%), Gaps = 2/159 (1%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIKA A K++P VN W +Q +D+SVAVAT GL+TPI+ +A ++GI ++
Sbjct: 330 DFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEI 389
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQE-L 270
+ ++K L++KA+DGKL P+EYQGG+ ++SNLGM+GI F A+INPPQ+ I+A G + L
Sbjct: 390 ADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVL 449
Query: 269 VIPDQSEPNG-FRTAKFVTFTASADHRVVDGAIGAQWMK 156
+ + E N + + +T T S+D RVVD + +++K
Sbjct: 450 KLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLK 488
>U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl
transferase protein.
Length = 375
Score = 144 bits (349), Expect = 3e-34
Identities = 71/159 (44%), Positives = 108/159 (67%), Gaps = 2/159 (1%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIKA A K++P VN W +Q +D+SVAVAT GL+TPI+ +A ++GI ++
Sbjct: 204 DFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEI 263
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQE-L 270
+ ++K L++KA+DGKL P+EYQGG+ ++SNLGM+GI F A+INPPQ+ I+A G + L
Sbjct: 264 ADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVL 323
Query: 269 VIPDQSEPNG-FRTAKFVTFTASADHRVVDGAIGAQWMK 156
+ + E N + + +T T S+D RVVD + +++K
Sbjct: 324 KLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLK 362
>AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing
component X protein.
Length = 501
Score = 144 bits (349), Expect = 3e-34
Identities = 71/159 (44%), Positives = 108/159 (67%), Gaps = 2/159 (1%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIKA A K++P VN W +Q +D+SVAVAT GL+TPI+ +A ++GI ++
Sbjct: 330 DFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEI 389
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQE-L 270
+ ++K L++KA+DGKL P+EYQGG+ ++SNLGM+GI F A+INPPQ+ I+A G + L
Sbjct: 390 ADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVL 449
Query: 269 VIPDQSEPNG-FRTAKFVTFTASADHRVVDGAIGAQWMK 156
+ + E N + + +T T S+D RVVD + +++K
Sbjct: 450 KLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLK 488
>AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide
dehydrogenase-binding protein protein.
Length = 501
Score = 144 bits (349), Expect = 3e-34
Identities = 71/159 (44%), Positives = 108/159 (67%), Gaps = 2/159 (1%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIKA A K++P VN W +Q +D+SVAVAT GL+TPI+ +A ++GI ++
Sbjct: 330 DFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEI 389
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQE-L 270
+ ++K L++KA+DGKL P+EYQGG+ ++SNLGM+GI F A+INPPQ+ I+A G + L
Sbjct: 390 ADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVL 449
Query: 269 VIPDQSEPNG-FRTAKFVTFTASADHRVVDGAIGAQWMK 156
+ + E N + + +T T S+D RVVD + +++K
Sbjct: 450 KLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLK 488
>BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase
complex, component X protein.
Length = 501
Score = 144 bits (348), Expect = 4e-34
Identities = 71/159 (44%), Positives = 108/159 (67%), Gaps = 2/159 (1%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIKA A K++P VN W +Q +D+SVAVAT GL+TPI+ +A ++GI ++
Sbjct: 330 DFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATVKGLLTPIIKDAAAKGIQEI 389
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQE-L 270
+ ++K L++KA+DGKL P+EYQGG+ ++SNLGM+GI F A+INPPQ+ I+A G + L
Sbjct: 390 ADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVL 449
Query: 269 VIPDQSEPNG-FRTAKFVTFTASADHRVVDGAIGAQWMK 156
+ + E N + + +T T S+D RVVD + +++K
Sbjct: 450 KLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLK 488
>X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide
S-acetyltransferase protein.
Length = 220
Score = 92.3 bits (219), Expect = 2e-18
Identities = 44/78 (56%), Positives = 57/78 (73%)
Frame = -1
Query: 626 DFIIKAVAAACKRVPTVNSHWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIIDL 447
DFIIK A AC +VP NS WM++ IRQ VDVSVAV+TP GLITPI+ NA +G+ +
Sbjct: 142 DFIIKRSALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETI 201
Query: 446 SKNMKQLAQKAKDGKLQP 393
+ ++ LA KA++GKLQP
Sbjct: 202 ANDVVSLATKAREGKLQP 219
>D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial
dihydrolipoamide succinyltransferase protein.
Length = 453
Score = 89.8 bits (213), Expect = 1e-17
Identities = 51/150 (34%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
Frame = -1
Query: 617 IKAVAAACKRVPTVNS----HWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
+KA A A + P VN+ E R + +D+SVAVATP GL+ P++ N ++ D
Sbjct: 285 VKASAFALQEQPVVNAVIDDTTKEVVYRDY--IDISVAVATPRGLVVPVIRNVEAMNFAD 342
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
+ + + +L +KA+ +L ++ GGT T+SN G++G IINPPQS I+ G+ +
Sbjct: 343 IERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTTIINPPQSAILGMHGIFDR 402
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDG 180
+ + R +V T DHR++DG
Sbjct: 403 PVAIGGKVE-VRPMMYVALT--YDHRLIDG 429
>L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 89.4 bits (212), Expect = 1e-17
Identities = 51/150 (34%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
Frame = -1
Query: 617 IKAVAAACKRVPTVNS----HWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
+KA A A + P VN+ E R + +D+SVAVATP GL+ P++ N ++ D
Sbjct: 285 VKASAFALQEQPVVNAVIDDTTKEVVYRDY--IDISVAVATPRGLVVPVIRNVEAMNFAD 342
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
+ + + +L +KA+ +L ++ GGT T+SN G++G IINPPQS I+ G+ +
Sbjct: 343 IERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDR 402
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDG 180
+ + R +V T DHR++DG
Sbjct: 403 PVAIGGKVE-VRPMMYVALT--YDHRLIDG 429
>D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 89.4 bits (212), Expect = 1e-17
Identities = 49/148 (33%), Positives = 82/148 (55%), Gaps = 2/148 (1%)
Frame = -1
Query: 617 IKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPILHNADSRGIIDLS 444
+KA A A + P VN+ ++ + +D+SVAVATP GL+ P++ N ++ D+
Sbjct: 285 VKASAFALQEQPVVNAVIDDTTKEVVYTDYIDISVAVATPRGLVVPVIRNVEAMNFADIE 344
Query: 443 KNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQELVI 264
+ + +L +KA+ +L ++ GGT T+SN G++G IINPPQS I+ G+ + +
Sbjct: 345 RTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPV 404
Query: 263 PDQSEPNGFRTAKFVTFTASADHRVVDG 180
+ R +V T DHR++DG
Sbjct: 405 AIGGKVE-VRPMMYVALT--YDHRLIDG 429
>CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein.
Length = 453
Score = 89.4 bits (212), Expect = 1e-17
Identities = 51/150 (34%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
Frame = -1
Query: 617 IKAVAAACKRVPTVNS----HWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
+KA A A + P VN+ E R + +D+SVAVATP GL+ P++ N ++ D
Sbjct: 285 VKASAFALQEQPVVNAVIDDTTKEVVYRDY--IDISVAVATPRGLVVPVIRNVEAMNFAD 342
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
+ + + +L +KA+ +L ++ GGT T+SN G++G IINPPQS I+ G+ +
Sbjct: 343 IERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDR 402
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDG 180
+ + R +V T DHR++DG
Sbjct: 403 PVAIGGKVE-VRPMMYVALT--YDHRLIDG 429
>BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 89.4 bits (212), Expect = 1e-17
Identities = 51/150 (34%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
Frame = -1
Query: 617 IKAVAAACKRVPTVNS----HWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
+KA A A + P VN+ E R + +D+SVAVATP GL+ P++ N ++ D
Sbjct: 285 VKASAFALQEQPVVNAVIDDTTKEVVYRDY--IDISVAVATPRGLVVPVIRNVEAMNFAD 342
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
+ + + +L +KA+ +L ++ GGT T+SN G++G IINPPQS I+ G+ +
Sbjct: 343 IERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDR 402
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDG 180
+ + R +V T DHR++DG
Sbjct: 403 PVAIGGKVE-VRPMMYVALT--YDHRLIDG 429
>BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 89.4 bits (212), Expect = 1e-17
Identities = 51/150 (34%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
Frame = -1
Query: 617 IKAVAAACKRVPTVNS----HWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
+KA A A + P VN+ E R + +D+SVAVATP GL+ P++ N ++ D
Sbjct: 285 VKASAFALQEQPVVNAVIDDTTKEVVYRDY--IDISVAVATPRGLVVPVIRNVEAMNFAD 342
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
+ + + +L +KA+ +L ++ GGT T+SN G++G IINPPQS I+ G+ +
Sbjct: 343 IERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDR 402
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDG 180
+ + R +V T DHR++DG
Sbjct: 403 PVAIGGKVE-VRPMMYVALT--YDHRLIDG 429
>AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein.
Length = 453
Score = 89.4 bits (212), Expect = 1e-17
Identities = 51/150 (34%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
Frame = -1
Query: 617 IKAVAAACKRVPTVNS----HWMESFIRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
+KA A A + P VN+ E R + +D+SVAVATP GL+ P++ N ++ D
Sbjct: 285 VKASAFALQEQPVVNAVIDDTTKEVVYRDY--IDISVAVATPRGLVVPVIRNVEAMNFAD 342
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
+ + + +L +KA+ +L ++ GGT T+SN G++G IINPPQS I+ G+ +
Sbjct: 343 IERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDR 402
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDG 180
+ + R +V T DHR++DG
Sbjct: 403 PVAIGGKVE-VRPMMYVALT--YDHRLIDG 429
>S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate
dehydrogenase complex dihydrolipoyl succinyltransferase
protein.
Length = 451
Score = 76.6 bits (180), Expect = 1e-13
Identities = 44/149 (29%), Positives = 82/149 (55%), Gaps = 3/149 (2%)
Frame = -1
Query: 617 IKAVAAACKRVPTVNSHWMESFIRQF---SNVDVSVAVATPTGLITPILHNADSRGIIDL 447
+KA A A + P VN+ ++ ++ +D+SVAVATP GL+ P++ N ++ D+
Sbjct: 284 VKASAFALQEQPVVNAV-IDDITKEVVYRDYIDISVAVATPQGLVVPVIRNVEAMNYADI 342
Query: 446 SKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQELV 267
+ + +L +KA+ + ++ GGT T+SN G++G ++F ++ P S I+ G+ +
Sbjct: 343 EQTITELGEKARKNEFAIEDMDGGTFTISNGGVFG-SLFEHPLSTPLSAILGMHGIFDKP 401
Query: 266 IPDQSEPNGFRTAKFVTFTASADHRVVDG 180
+ + R +V T DHR++DG
Sbjct: 402 VAIGGKVE-VRPMMYVALT--YDHRLIDG 427
>X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein.
Length = 482
Score = 76.2 bits (179), Expect = 1e-13
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Frame = -1
Query: 623 FIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
F +KA + + P +N+ E+ I ++ ++ +A+ T GLI P + N I D
Sbjct: 310 FFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFD 369
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
++ + +L + G+L + GGT T+SN+G G T +I PP+ I A G ++
Sbjct: 370 IATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIK-- 427
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDGA 177
IP ++ A+ + + SADHRV+DGA
Sbjct: 428 AIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 458
>J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched
chain acyltransferase mRNA, complete cds. ).
Length = 477
Score = 76.2 bits (179), Expect = 1e-13
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Frame = -1
Query: 623 FIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
F +KA + + P +N+ E+ I ++ ++ +A+ T GLI P + N I D
Sbjct: 305 FFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFD 364
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
++ + +L + G+L + GGT T+SN+G G T +I PP+ I A G ++
Sbjct: 365 IATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIK-- 422
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDGA 177
IP ++ A+ + + SADHRV+DGA
Sbjct: 423 AIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 453
>BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase (E2 component of branched chain ke
protein.
Length = 482
Score = 76.2 bits (179), Expect = 1e-13
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Frame = -1
Query: 623 FIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
F +KA + + P +N+ E+ I ++ ++ +A+ T GLI P + N I D
Sbjct: 310 FFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFD 369
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
++ + +L + G+L + GGT T+SN+G G T +I PP+ I A G ++
Sbjct: 370 IATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIK-- 427
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDGA 177
IP ++ A+ + + SADHRV+DGA
Sbjct: 428 AIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 458
>BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 76.2 bits (179), Expect = 1e-13
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Frame = -1
Query: 623 FIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
F +KA + + P +N+ E+ I ++ ++ +A+ T GLI P + N I D
Sbjct: 310 FFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFD 369
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
++ + +L + G+L + GGT T+SN+G G T +I PP+ I A G ++
Sbjct: 370 IATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIK-- 427
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDGA 177
IP ++ A+ + + SADHRV+DGA
Sbjct: 428 AIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 458
>M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylase
protein.
Length = 477
Score = 73.7 bits (173), Expect = 7e-13
Identities = 45/151 (29%), Positives = 77/151 (50%), Gaps = 2/151 (1%)
Frame = -1
Query: 623 FIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
F +KA + P +N+ E+ I ++ ++ +A+ T G+I P + N I D
Sbjct: 305 FFLKAASLGLLPFPILNASVDENCQNITYKASHNIGIAMDTEQGVIVPNVKNVQICSIFD 364
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
++ + +L + G+L + GGT T+SN+G G T +I PP+ I A G ++
Sbjct: 365 IATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIK-- 422
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDGA 177
IP ++ A+ + + SADHRV+DGA
Sbjct: 423 AIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 453
>AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 73.7 bits (173), Expect = 7e-13
Identities = 45/151 (29%), Positives = 77/151 (50%), Gaps = 2/151 (1%)
Frame = -1
Query: 623 FIIKAVAAACKRVPTVNSHWMESF--IRQFSNVDVSVAVATPTGLITPILHNADSRGIID 450
F +KA + + P +N+ E+ I ++ ++ +A+ T GLI P + N I D
Sbjct: 310 FFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFD 369
Query: 449 LSKNMKQLAQKAKDGKLQPQEYQGGTVTVSNLGMYGITMFNAIINPPQSFIIACGGVQEL 270
++ + +L + +L + GGT T+SN+G G T +I PP+ I A G ++
Sbjct: 370 IATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIK-- 427
Query: 269 VIPDQSEPNGFRTAKFVTFTASADHRVVDGA 177
IP ++ A+ + + SADHRV+DGA
Sbjct: 428 AIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 458
>AM260536-1|CAJ97431.1| 1266|Homo sapiens ponsin protein.
Length = 1266
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 467 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 507
>AL158165-8|CAI14385.1| 1004|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 1004
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 483 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 523
>AL158165-7|CAI14379.1| 1292|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 1292
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 513 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 553
>AL158165-6|CAI14380.1| 811|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 811
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 312 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 352
>AL158165-5|CAI14381.1| 1151|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 1151
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 535 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 575
>AL158165-2|CAI14383.1| 905|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 905
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 398 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 438
>AJ489942-1|CAD34588.1| 846|Homo sapiens c-Cbl associated protein
protein.
Length = 846
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 381 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 421
>AF356527-1|AAK37565.1| 905|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 905
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 398 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 438
>AF356526-1|AAK37564.1| 1151|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 1151
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 535 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 575
>AF356525-1|AAK37563.1| 1292|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 1292
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 513 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 553
>AF330623-1|AAK57479.1| 811|Homo sapiens brain R85FL protein.
Length = 811
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 312 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 352
>AF136381-1|AAF22175.1| 1004|Homo sapiens c-Cbl-associated protein
SH3P12 protein.
Length = 1004
Score = 30.7 bits (66), Expect = 6.3
Identities = 14/41 (34%), Positives = 23/41 (56%)
Frame = -3
Query: 183 RSDRRSMDESIXRRTSKIPPTSFYK*RNGPTSIQLNERMSR 61
R+D D+ + R + P S Y+ + G +S+ NE+MSR
Sbjct: 483 RNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSR 523
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,625,272
Number of Sequences: 237096
Number of extensions: 2383588
Number of successful extensions: 4262
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 4067
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4250
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9701808132
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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