Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP03_T7_B05
(865 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U07681-1|AAA85639.1| 366|Homo sapiens NAD(H)-specific isocitrat... 109 1e-23
BC021967-1|AAH21967.1| 366|Homo sapiens isocitrate dehydrogenas... 109 1e-23
AL442090-1|CAC09449.1| 288|Homo sapiens hypothetical protein pr... 109 1e-23
AK222973-1|BAD96693.1| 366|Homo sapiens isocitrate dehydrogenas... 109 1e-23
AL049712-2|CAC01443.1| 383|Homo sapiens isocitrate dehydrogenas... 71 4e-12
AF023265-1|AAD09339.1| 383|Homo sapiens NAD+-specific isocitrat... 71 4e-12
U49283-1|AAB94295.1| 385|Homo sapiens NAD+-specific isocitrate ... 62 3e-09
BC001960-1|AAH01960.1| 385|Homo sapiens isocitrate dehydrogenas... 62 3e-09
AL050094-1|CAB43266.1| 259|Homo sapiens hypothetical protein pr... 62 3e-09
AL049712-1|CAC01442.2| 385|Homo sapiens isocitrate dehydrogenas... 62 3e-09
AK001905-1|BAA91971.1| 233|Homo sapiens protein ( Homo sapiens ... 62 3e-09
AF046929-1|AAF20164.1| 156|Homo sapiens NAD+-specific isocitrat... 62 3e-09
AF023266-1|AAD09340.1| 387|Homo sapiens NAD+-specific isocitrat... 62 3e-09
Z68907-1|CAA93143.1| 393|Homo sapiens NAD (H)-specific isocitra... 52 2e-06
Z68129-1|CAA92214.1| 393|Homo sapiens NAD(H)-specific isocitrat... 52 2e-06
U40272-1|AAD09357.1| 393|Homo sapiens NAD+-specific isocitrate ... 52 2e-06
BC001902-1|AAH01902.1| 393|Homo sapiens isocitrate dehydrogenas... 52 2e-06
BC000933-1|AAH00933.1| 393|Homo sapiens isocitrate dehydrogenas... 52 2e-06
U69269-1|AAB70116.1| 210|Homo sapiens NAD (H)-specific isocitra... 44 5e-04
U69268-1|AAB70115.1| 296|Homo sapiens NAD (H)-specific isocitra... 44 5e-04
AB209206-1|BAD92443.1| 174|Homo sapiens isocitrate dehydrogenas... 44 5e-04
>U07681-1|AAA85639.1| 366|Homo sapiens NAD(H)-specific isocitrate
dehydrogenase alpha subunit precursor protein.
Length = 366
Score = 109 bits (262), Expect = 1e-23
Identities = 48/74 (64%), Positives = 61/74 (82%)
Frame = -2
Query: 609 VHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGT 430
VHGTAPDIAGKDMANPTALLLSA+MMLRH+ L DHA ++ AC+ +++G++LT DLGG
Sbjct: 289 VHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGN 348
Query: 429 AKCSEFTNAIISKL 388
AKCS+FT I ++
Sbjct: 349 AKCSDFTEEICRRV 362
>BC021967-1|AAH21967.1| 366|Homo sapiens isocitrate dehydrogenase 3
(NAD+) alpha protein.
Length = 366
Score = 109 bits (262), Expect = 1e-23
Identities = 48/74 (64%), Positives = 61/74 (82%)
Frame = -2
Query: 609 VHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGT 430
VHGTAPDIAGKDMANPTALLLSA+MMLRH+ L DHA ++ AC+ +++G++LT DLGG
Sbjct: 289 VHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGN 348
Query: 429 AKCSEFTNAIISKL 388
AKCS+FT I ++
Sbjct: 349 AKCSDFTEEICRRV 362
>AL442090-1|CAC09449.1| 288|Homo sapiens hypothetical protein
protein.
Length = 288
Score = 109 bits (262), Expect = 1e-23
Identities = 48/74 (64%), Positives = 61/74 (82%)
Frame = -2
Query: 609 VHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGT 430
VHGTAPDIAGKDMANPTALLLSA+MMLRH+ L DHA ++ AC+ +++G++LT DLGG
Sbjct: 211 VHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGN 270
Query: 429 AKCSEFTNAIISKL 388
AKCS+FT I ++
Sbjct: 271 AKCSDFTEEICRRV 284
>AK222973-1|BAD96693.1| 366|Homo sapiens isocitrate dehydrogenase 3
(NAD+) alpha precursor variant protein.
Length = 366
Score = 109 bits (262), Expect = 1e-23
Identities = 48/74 (64%), Positives = 61/74 (82%)
Frame = -2
Query: 609 VHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGT 430
VHGTAPDIAGKDMANPTALLLSA+MMLRH+ L DHA ++ AC+ +++G++LT DLGG
Sbjct: 289 VHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGN 348
Query: 429 AKCSEFTNAIISKL 388
AKCS+FT I ++
Sbjct: 349 AKCSDFTEEICRRV 362
>AL049712-2|CAC01443.1| 383|Homo sapiens isocitrate dehydrogenase 3
(NAD+) beta protein.
Length = 383
Score = 71.3 bits (167), Expect = 4e-12
Identities = 31/65 (47%), Positives = 47/65 (72%)
Frame = -2
Query: 582 GKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGTAKCSEFTNA 403
G+++ANPTA+LLSA MLRHL L H+ ++ +A +V++ G+ T D+GG A C +FT A
Sbjct: 316 GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTSDMGGYATCHDFTEA 375
Query: 402 IISKL 388
+I+ L
Sbjct: 376 VIAAL 380
>AF023265-1|AAD09339.1| 383|Homo sapiens NAD+-specific isocitrate
dehydrogenase beta subunit isoform A protein.
Length = 383
Score = 71.3 bits (167), Expect = 4e-12
Identities = 31/65 (47%), Positives = 47/65 (72%)
Frame = -2
Query: 582 GKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGTAKCSEFTNA 403
G+++ANPTA+LLSA MLRHL L H+ ++ +A +V++ G+ T D+GG A C +FT A
Sbjct: 316 GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTSDMGGYATCHDFTEA 375
Query: 402 IISKL 388
+I+ L
Sbjct: 376 VIAAL 380
>U49283-1|AAB94295.1| 385|Homo sapiens NAD+-specific isocitrate
dehydrogenase beta precursor protein.
Length = 385
Score = 62.1 bits (144), Expect = 3e-09
Identities = 27/65 (41%), Positives = 45/65 (69%)
Frame = -2
Query: 582 GKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGTAKCSEFTNA 403
G+++ANPTA+LLSA MLRHL L H+ ++ +A +V++ G+ T D+GG + ++F +
Sbjct: 316 GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKS 375
Query: 402 IISKL 388
+I L
Sbjct: 376 VIGHL 380
>BC001960-1|AAH01960.1| 385|Homo sapiens isocitrate dehydrogenase 3
(NAD+) beta protein.
Length = 385
Score = 62.1 bits (144), Expect = 3e-09
Identities = 27/65 (41%), Positives = 45/65 (69%)
Frame = -2
Query: 582 GKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGTAKCSEFTNA 403
G+++ANPTA+LLSA MLRHL L H+ ++ +A +V++ G+ T D+GG + ++F +
Sbjct: 316 GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKS 375
Query: 402 IISKL 388
+I L
Sbjct: 376 VIGHL 380
>AL050094-1|CAB43266.1| 259|Homo sapiens hypothetical protein
protein.
Length = 259
Score = 62.1 bits (144), Expect = 3e-09
Identities = 27/65 (41%), Positives = 45/65 (69%)
Frame = -2
Query: 582 GKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGTAKCSEFTNA 403
G+++ANPTA+LLSA MLRHL L H+ ++ +A +V++ G+ T D+GG + ++F +
Sbjct: 190 GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKS 249
Query: 402 IISKL 388
+I L
Sbjct: 250 VIGHL 254
>AL049712-1|CAC01442.2| 385|Homo sapiens isocitrate dehydrogenase 3
(NAD+) beta protein.
Length = 385
Score = 62.1 bits (144), Expect = 3e-09
Identities = 27/65 (41%), Positives = 45/65 (69%)
Frame = -2
Query: 582 GKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGTAKCSEFTNA 403
G+++ANPTA+LLSA MLRHL L H+ ++ +A +V++ G+ T D+GG + ++F +
Sbjct: 316 GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKS 375
Query: 402 IISKL 388
+I L
Sbjct: 376 VIGHL 380
>AK001905-1|BAA91971.1| 233|Homo sapiens protein ( Homo sapiens
cDNA FLJ11043 fis, clone PLACE1004437, highly similar to
Human NAD+-specific isocitrate dehydrogenase beta
subunit ).
Length = 233
Score = 62.1 bits (144), Expect = 3e-09
Identities = 27/65 (41%), Positives = 45/65 (69%)
Frame = -2
Query: 582 GKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGTAKCSEFTNA 403
G+++ANPTA+LLSA MLRHL L H+ ++ +A +V++ G+ T D+GG + ++F +
Sbjct: 164 GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKS 223
Query: 402 IISKL 388
+I L
Sbjct: 224 VIGHL 228
>AF046929-1|AAF20164.1| 156|Homo sapiens NAD+-specific isocitrate
dehydrogenase b subunit protein.
Length = 156
Score = 62.1 bits (144), Expect = 3e-09
Identities = 27/65 (41%), Positives = 45/65 (69%)
Frame = -2
Query: 582 GKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGTAKCSEFTNA 403
G+++ANPTA+LLSA MLRHL L H+ ++ +A +V++ G+ T D+GG + ++F +
Sbjct: 87 GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKS 146
Query: 402 IISKL 388
+I L
Sbjct: 147 VIGHL 151
>AF023266-1|AAD09340.1| 387|Homo sapiens NAD+-specific isocitrate
dehydrogenase beta subunit isoform B protein.
Length = 387
Score = 62.1 bits (144), Expect = 3e-09
Identities = 27/65 (41%), Positives = 45/65 (69%)
Frame = -2
Query: 582 GKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLREGRALTGDLGGTAKCSEFTNA 403
G+++ANPTA+LLSA MLRHL L H+ ++ +A +V++ G+ T D+GG + ++F +
Sbjct: 316 GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKS 375
Query: 402 IISKL 388
+I L
Sbjct: 376 VIGHL 380
>Z68907-1|CAA93143.1| 393|Homo sapiens NAD (H)-specific isocitrate
dehydrogenase gamma subunit precursor protein.
Length = 393
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/82 (34%), Positives = 40/82 (48%)
Frame = -2
Query: 642 YSHAETRAXRVVHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLRE 463
Y H T IA K++ANPTA LL++ MML HL+L+ +A ++ A +
Sbjct: 299 YGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDN 358
Query: 462 GRALTGDLGGTAKCSEFTNAII 397
T D+GG SE +I
Sbjct: 359 ENMHTPDIGGQGTTSEAIQDVI 380
>Z68129-1|CAA92214.1| 393|Homo sapiens NAD(H)-specific isocitrate
dehydrogenase gamma-subunit precursor protein.
Length = 393
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/82 (34%), Positives = 40/82 (48%)
Frame = -2
Query: 642 YSHAETRAXRVVHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLRE 463
Y H T IA K++ANPTA LL++ MML HL+L+ +A ++ A +
Sbjct: 299 YGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDN 358
Query: 462 GRALTGDLGGTAKCSEFTNAII 397
T D+GG SE +I
Sbjct: 359 ENMHTPDIGGQGTTSEAIQDVI 380
>U40272-1|AAD09357.1| 393|Homo sapiens NAD+-specific isocitrate
dehydrogenase gamma subunit precursor protein.
Length = 393
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/82 (34%), Positives = 40/82 (48%)
Frame = -2
Query: 642 YSHAETRAXRVVHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLRE 463
Y H T IA K++ANPTA LL++ MML HL+L+ +A ++ A +
Sbjct: 299 YGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDN 358
Query: 462 GRALTGDLGGTAKCSEFTNAII 397
T D+GG SE +I
Sbjct: 359 ENMHTPDIGGQGTTSEAIQDVI 380
>BC001902-1|AAH01902.1| 393|Homo sapiens isocitrate dehydrogenase 3
(NAD+) gamma protein.
Length = 393
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/82 (34%), Positives = 40/82 (48%)
Frame = -2
Query: 642 YSHAETRAXRVVHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLRE 463
Y H T IA K++ANPTA LL++ MML HL+L+ +A ++ A +
Sbjct: 299 YGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDN 358
Query: 462 GRALTGDLGGTAKCSEFTNAII 397
T D+GG SE +I
Sbjct: 359 ENMHTPDIGGQGTTSEAIQDVI 380
>BC000933-1|AAH00933.1| 393|Homo sapiens isocitrate dehydrogenase 3
(NAD+) gamma protein.
Length = 393
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/82 (34%), Positives = 40/82 (48%)
Frame = -2
Query: 642 YSHAETRAXRVVHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNACYEVLRE 463
Y H T IA K++ANPTA LL++ MML HL+L+ +A ++ A +
Sbjct: 299 YGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDN 358
Query: 462 GRALTGDLGGTAKCSEFTNAII 397
T D+GG SE +I
Sbjct: 359 ENMHTPDIGGQGTTSEAIQDVI 380
>U69269-1|AAB70116.1| 210|Homo sapiens NAD (H)-specific isocitrate
dehydrogenase gamma subunit protein.
Length = 210
Score = 44.4 bits (100), Expect = 5e-04
Identities = 21/53 (39%), Positives = 30/53 (56%)
Frame = -2
Query: 642 YSHAETRAXRVVHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNA 484
Y H T IA K++ANPTA LL++ MML HL+L+ +A ++ A
Sbjct: 104 YGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKA 156
>U69268-1|AAB70115.1| 296|Homo sapiens NAD (H)-specific isocitrate
dehydrogenase gamma subunit protein.
Length = 296
Score = 44.4 bits (100), Expect = 5e-04
Identities = 21/53 (39%), Positives = 30/53 (56%)
Frame = -2
Query: 642 YSHAETRAXRVVHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNA 484
Y H T IA K++ANPTA LL++ MML HL+L+ +A ++ A
Sbjct: 215 YGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKA 267
>AB209206-1|BAD92443.1| 174|Homo sapiens isocitrate dehydrogenase 3
(NAD+) gamma isoform b precursor variant protein.
Length = 174
Score = 44.4 bits (100), Expect = 5e-04
Identities = 21/53 (39%), Positives = 30/53 (56%)
Frame = -2
Query: 642 YSHAETRAXRVVHGTAPDIAGKDMANPTALLLSAIMMLRHLQLNDHADLVQNA 484
Y H T IA K++ANPTA LL++ MML HL+L+ +A ++ A
Sbjct: 93 YGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKA 145
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,756,671
Number of Sequences: 237096
Number of extensions: 1532758
Number of successful extensions: 2523
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 2465
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2511
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 11039988564
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -