Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP03_T7_B02
(803 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR456737-1|CAG33018.1| 598|Homo sapiens POLA2 protein. 166 9e-41
BC002990-1|AAH02990.1| 598|Homo sapiens polymerase (DNA directe... 166 9e-41
BC001347-1|AAH01347.1| 598|Homo sapiens polymerase (DNA directe... 166 9e-41
L24559-1|AAA16459.1| 598|Homo sapiens DNA polymerase alpha prot... 165 1e-40
>CR456737-1|CAG33018.1| 598|Homo sapiens POLA2 protein.
Length = 598
Score = 166 bits (403), Expect = 9e-41
Identities = 95/248 (38%), Positives = 140/248 (56%), Gaps = 13/248 (5%)
Frame = -3
Query: 795 SXNXAYXPLKDMVTYXNTHXPHVVIMTGPFXDSEHXQGQRQYDGRDI*LVVWEILDSXGE 616
S + Y PL D++ N P V I+ GPF D++H Q + + + L + E
Sbjct: 352 SDSITYDPLLDLIAVINHDRPDVCILFGPFLDAKHEQVENCLLTSPFEDIFKQCLRTIIE 411
Query: 615 LSNTSPVTKIYIVSNLKDAFHVNVYPTPPY----VSRRKHPNIHFVPDPCTLTINGIHVG 448
+ +S +++ S L+D H VYP PP+ +SR + FV +PC+L+ING+ G
Sbjct: 412 GTRSSGSHLVFVPS-LRDVHHEPVYPQPPFSYSDLSREDKKQVQFVSEPCSLSINGVIFG 470
Query: 447 VTSTDILMHISQEEISLGTG-GDKLSRLASHVLSQQTYYPLCPAP--VPLDXXXXXXXXX 277
+TSTD+L H+ EEIS +G D+ SR+ H+L+Q++YYPL P + +D
Sbjct: 471 LTSTDLLFHLGAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQ 530
Query: 276 XXASPHLLVLPSNFRYFVKDVNGCVVVNPEHLTKGTGGGTFTRVLI---DSDNATKR--- 115
+P +L++PS RYFVKDV GCV VNP LTKG GGTF R+ + +D A ++
Sbjct: 531 LPVTPDVLIIPSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQSPC 590
Query: 114 IAAQIVRI 91
IA Q+VRI
Sbjct: 591 IAVQVVRI 598
>BC002990-1|AAH02990.1| 598|Homo sapiens polymerase (DNA directed),
alpha 2 (70kD subunit) protein.
Length = 598
Score = 166 bits (403), Expect = 9e-41
Identities = 95/248 (38%), Positives = 140/248 (56%), Gaps = 13/248 (5%)
Frame = -3
Query: 795 SXNXAYXPLKDMVTYXNTHXPHVVIMTGPFXDSEHXQGQRQYDGRDI*LVVWEILDSXGE 616
S + Y PL D++ N P V I+ GPF D++H Q + + + L + E
Sbjct: 352 SDSITYDPLLDLIAVINHDRPDVCILFGPFLDAKHEQVENCLLTSPFEDIFKQCLRTIIE 411
Query: 615 LSNTSPVTKIYIVSNLKDAFHVNVYPTPPY----VSRRKHPNIHFVPDPCTLTINGIHVG 448
+ +S +++ S L+D H VYP PP+ +SR + FV +PC+L+ING+ G
Sbjct: 412 GTRSSGSHLVFVPS-LRDVHHEPVYPQPPFSYSDLSREDKKQVQFVSEPCSLSINGVIFG 470
Query: 447 VTSTDILMHISQEEISLGTG-GDKLSRLASHVLSQQTYYPLCPAP--VPLDXXXXXXXXX 277
+TSTD+L H+ EEIS +G D+ SR+ H+L+Q++YYPL P + +D
Sbjct: 471 LTSTDLLFHLGAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQ 530
Query: 276 XXASPHLLVLPSNFRYFVKDVNGCVVVNPEHLTKGTGGGTFTRVLI---DSDNATKR--- 115
+P +L++PS RYFVKDV GCV VNP LTKG GGTF R+ + +D A ++
Sbjct: 531 LPVTPDVLIIPSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQSPC 590
Query: 114 IAAQIVRI 91
IA Q+VRI
Sbjct: 591 IAVQVVRI 598
>BC001347-1|AAH01347.1| 598|Homo sapiens polymerase (DNA directed),
alpha 2 (70kD subunit) protein.
Length = 598
Score = 166 bits (403), Expect = 9e-41
Identities = 95/248 (38%), Positives = 140/248 (56%), Gaps = 13/248 (5%)
Frame = -3
Query: 795 SXNXAYXPLKDMVTYXNTHXPHVVIMTGPFXDSEHXQGQRQYDGRDI*LVVWEILDSXGE 616
S + Y PL D++ N P V I+ GPF D++H Q + + + L + E
Sbjct: 352 SDSITYDPLLDLIAVINHDRPDVCILFGPFLDAKHEQVENCLLTSPFEDIFKQCLRTIIE 411
Query: 615 LSNTSPVTKIYIVSNLKDAFHVNVYPTPPY----VSRRKHPNIHFVPDPCTLTINGIHVG 448
+ +S +++ S L+D H VYP PP+ +SR + FV +PC+L+ING+ G
Sbjct: 412 GTRSSGSHLVFVPS-LRDVHHEPVYPQPPFSYSDLSREDKKQVQFVSEPCSLSINGVIFG 470
Query: 447 VTSTDILMHISQEEISLGTG-GDKLSRLASHVLSQQTYYPLCPAP--VPLDXXXXXXXXX 277
+TSTD+L H+ EEIS +G D+ SR+ H+L+Q++YYPL P + +D
Sbjct: 471 LTSTDLLFHLGAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQ 530
Query: 276 XXASPHLLVLPSNFRYFVKDVNGCVVVNPEHLTKGTGGGTFTRVLI---DSDNATKR--- 115
+P +L++PS RYFVKDV GCV VNP LTKG GGTF R+ + +D A ++
Sbjct: 531 LPVTPDVLIIPSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQSPC 590
Query: 114 IAAQIVRI 91
IA Q+VRI
Sbjct: 591 IAVQVVRI 598
>L24559-1|AAA16459.1| 598|Homo sapiens DNA polymerase alpha protein.
Length = 598
Score = 165 bits (402), Expect = 1e-40
Identities = 95/248 (38%), Positives = 140/248 (56%), Gaps = 13/248 (5%)
Frame = -3
Query: 795 SXNXAYXPLKDMVTYXNTHXPHVVIMTGPFXDSEHXQGQRQYDGRDI*LVVWEILDSXGE 616
S + Y PL D++ N P V I+ GPF +S+H Q + + + L + E
Sbjct: 352 SDSITYDPLLDLIAVINHDRPDVCILFGPFLESKHEQVENCLLTSPFEDIFKQCLRTIIE 411
Query: 615 LSNTSPVTKIYIVSNLKDAFHVNVYPTPPY----VSRRKHPNIHFVPDPCTLTINGIHVG 448
+ +S +++ S L+D H VYP PP+ +SR + FV +PC+L+ING+ G
Sbjct: 412 GTRSSGSHLVFVPS-LRDVHHEPVYPQPPFSYSDLSREDKKQVQFVSEPCSLSINGVIFG 470
Query: 447 VTSTDILMHISQEEISLGTG-GDKLSRLASHVLSQQTYYPLCPAP--VPLDXXXXXXXXX 277
+TSTD+L H+ EEIS +G D+ SR+ H+L+Q++YYPL P + +D
Sbjct: 471 LTSTDLLFHLGAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQ 530
Query: 276 XXASPHLLVLPSNFRYFVKDVNGCVVVNPEHLTKGTGGGTFTRVLI---DSDNATKR--- 115
+P +L++PS RYFVKDV GCV VNP LTKG GGTF R+ + +D A ++
Sbjct: 531 LPVTPDVLIIPSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQSPC 590
Query: 114 IAAQIVRI 91
IA Q+VRI
Sbjct: 591 IAVQVVRI 598
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,770,973
Number of Sequences: 237096
Number of extensions: 2171350
Number of successful extensions: 3801
Number of sequences better than 10.0: 4
Number of HSP's better than 10.0 without gapping: 3690
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3785
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9924838204
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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