Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP03_FL5_O21
(843 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein. 268 1e-71
AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2 prot... 268 1e-71
AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens ... 267 4e-71
AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1 prot... 266 5e-71
AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein. 266 5e-71
AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens ... 98 3e-20
M76558-1|AAA58402.1| 2161|Homo sapiens calcium channel alpha-1D ... 33 0.98
M83566-1|AAA35629.1| 2181|Homo sapiens calcium channel alpha-1 s... 32 3.0
D43747-1|BAA07804.1| 2170|Homo sapiens voltage-dependent calcium... 32 3.0
AB209171-1|BAD92408.1| 1854|Homo sapiens calcium channel, voltag... 32 3.0
>BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein.
Length = 418
Score = 268 bits (658), Expect = 1e-71
Identities = 135/179 (75%), Positives = 143/179 (79%)
Frame = +2
Query: 272 TLFIFLVCCQIPLFGIMSSDSADPFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGA 451
TLFIFLVCCQIPLFGIMSSDSADPFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGA
Sbjct: 38 TLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGA 97
Query: 452 KIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFV 631
KIIEVGDTPKDRALFNGAQKLFGM+IT+GQAIVYVMTGMYG+P+E+GAG+CLLIIIQLFV
Sbjct: 98 KIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFV 157
Query: 632 AGLIVLLLDEXXXXXXXXXXXXXXXXXXKHL*NHCMEGISPATXXTGRGQNSXGAVIXL 808
AGLIVLLLDE + SP T TGRG GAVI L
Sbjct: 158 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIAL 216
Score = 81.0 bits (191), Expect = 5e-15
Identities = 36/43 (83%), Positives = 39/43 (90%)
Frame = +1
Query: 160 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAIHIIYFL 288
MGIKFLEVIKPFC++LPEI KPERKIQFREKVLWTAI + FL
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFL 43
>AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2
protein.
Length = 476
Score = 268 bits (658), Expect = 1e-71
Identities = 135/179 (75%), Positives = 143/179 (79%)
Frame = +2
Query: 272 TLFIFLVCCQIPLFGIMSSDSADPFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGA 451
TLFIFLVCCQIPLFGIMSSDSADPFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGA
Sbjct: 38 TLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGA 97
Query: 452 KIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFV 631
KIIEVGDTPKDRALFNGAQKLFGM+IT+GQAIVYVMTGMYG+P+E+GAG+CLLIIIQLFV
Sbjct: 98 KIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFV 157
Query: 632 AGLIVLLLDEXXXXXXXXXXXXXXXXXXKHL*NHCMEGISPATXXTGRGQNSXGAVIXL 808
AGLIVLLLDE + SP T TGRG GAVI L
Sbjct: 158 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIAL 216
Score = 81.0 bits (191), Expect = 5e-15
Identities = 36/43 (83%), Positives = 39/43 (90%)
Frame = +1
Query: 160 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAIHIIYFL 288
MGIKFLEVIKPFC++LPEI KPERKIQFREKVLWTAI + FL
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFL 43
>AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens
cDNA FLJ12578 fis, clone NT2RM4001054, moderately
similar to Homo sapiens sec61 homolog mRNA. ).
Length = 437
Score = 267 bits (654), Expect = 4e-71
Identities = 134/179 (74%), Positives = 143/179 (79%)
Frame = +2
Query: 272 TLFIFLVCCQIPLFGIMSSDSADPFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGA 451
TLFIFLVCCQIPLFGIMSSDSADPFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGA
Sbjct: 38 TLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGA 97
Query: 452 KIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFV 631
KIIEVGDTPKDRALFNGAQKLFGM+IT+GQAIVYV+TGMYG+P+E+GAG+CLLIIIQLFV
Sbjct: 98 KIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVITGMYGDPAEMGAGICLLIIIQLFV 157
Query: 632 AGLIVLLLDEXXXXXXXXXXXXXXXXXXKHL*NHCMEGISPATXXTGRGQNSXGAVIXL 808
AGLIVLLLDE + SP T TGRG GAVI L
Sbjct: 158 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIAL 216
Score = 78.2 bits (184), Expect = 3e-14
Identities = 35/43 (81%), Positives = 38/43 (88%)
Frame = +1
Query: 160 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAIHIIYFL 288
MGIKFLEVIKPFC++ PEI KPERKIQFREKVLWTAI + FL
Sbjct: 1 MGIKFLEVIKPFCAVPPEIQKPERKIQFREKVLWTAITLFIFL 43
>AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1
protein.
Length = 476
Score = 266 bits (653), Expect = 5e-71
Identities = 133/179 (74%), Positives = 142/179 (79%)
Frame = +2
Query: 272 TLFIFLVCCQIPLFGIMSSDSADPFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGA 451
TLFIFLVCCQIPLFGIMSSDSADPFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGA
Sbjct: 38 TLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGA 97
Query: 452 KIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFV 631
KIIEVGDTPKDRALFNGAQKLFGM+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFV
Sbjct: 98 KIIEVGDTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFV 157
Query: 632 AGLIVLLLDEXXXXXXXXXXXXXXXXXXKHL*NHCMEGISPATXXTGRGQNSXGAVIXL 808
AGLIVLLLDE + SP T TGRG GA+I L
Sbjct: 158 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIAL 216
Score = 76.6 bits (180), Expect = 1e-13
Identities = 35/43 (81%), Positives = 37/43 (86%)
Frame = +1
Query: 160 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAIHIIYFL 288
M IKFLEVIKPFC ILPEI KPERKIQF+EKVLWTAI + FL
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFL 43
>AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein.
Length = 476
Score = 266 bits (653), Expect = 5e-71
Identities = 133/179 (74%), Positives = 142/179 (79%)
Frame = +2
Query: 272 TLFIFLVCCQIPLFGIMSSDSADPFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGA 451
TLFIFLVCCQIPLFGIMSSDSADPFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGA
Sbjct: 38 TLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGA 97
Query: 452 KIIEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFV 631
KIIEVGDTPKDRALFNGAQKLFGM+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFV
Sbjct: 98 KIIEVGDTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFV 157
Query: 632 AGLIVLLLDEXXXXXXXXXXXXXXXXXXKHL*NHCMEGISPATXXTGRGQNSXGAVIXL 808
AGLIVLLLDE + SP T TGRG GA+I L
Sbjct: 158 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIAL 216
Score = 76.6 bits (180), Expect = 1e-13
Identities = 35/43 (81%), Positives = 37/43 (86%)
Frame = +1
Query: 160 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAIHIIYFL 288
M IKFLEVIKPFC ILPEI KPERKIQF+EKVLWTAI + FL
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFL 43
>AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens
cDNA FLJ90447 fis, clone NT2RP3001240, highly similar to
Canis familiaris sec61 homologue mRNA. ).
Length = 356
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/96 (53%), Positives = 59/96 (61%)
Frame = +2
Query: 521 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLLLDEXXXXXXXXXXXXX 700
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAGLIVLLLDE
Sbjct: 1 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS 60
Query: 701 XXXXXKHL*NHCMEGISPATXXTGRGQNSXGAVIXL 808
+ SP T TGRG GA+I L
Sbjct: 61 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIAL 96
>M76558-1|AAA58402.1| 2161|Homo sapiens calcium channel alpha-1D
subunit protein.
Length = 2161
Score = 33.5 bits (73), Expect = 0.98
Identities = 34/101 (33%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Frame = +2
Query: 365 LASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALF-NGAQKLFGMV-ITVG 538
+ S+ L+ L + I+ S L MQL G +T R+ F N Q L + I G
Sbjct: 647 MKSSASLLLLLFLFIIIFSLLGMQLFGGK--FNFDETQTKRSTFDNFPQALLTVFQILTG 704
Query: 539 Q---AIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLL 652
+ A++Y YG PS G VC+ II LF+ G +LL
Sbjct: 705 EDWNAVMYDGIMAYGGPSSSGMIVCIYFII-LFICGNYILL 744
>M83566-1|AAA35629.1| 2181|Homo sapiens calcium channel alpha-1
subunit protein.
Length = 2181
Score = 31.9 bits (69), Expect = 3.0
Identities = 33/94 (35%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Frame = +2
Query: 386 LMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALF-NGAQKLFGMV-ITVGQ---AIV 550
L+ L + I+ S L MQL G +T R+ F N Q L + I G+ A++
Sbjct: 674 LLLLFLFIIIFSLLGMQLFGGK--FNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVM 731
Query: 551 YVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLL 652
Y YG PS G VC+ II LF+ G +LL
Sbjct: 732 YDGIMAYGGPSSSGMIVCIYFII-LFICGNYILL 764
>D43747-1|BAA07804.1| 2170|Homo sapiens voltage-dependent calcium
channel alpha1 subunit, CACN4 protein.
Length = 2170
Score = 31.9 bits (69), Expect = 3.0
Identities = 33/94 (35%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Frame = +2
Query: 386 LMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALF-NGAQKLFGMV-ITVGQ---AIV 550
L+ L + I+ S L MQL G +T R+ F N Q L + I G+ A++
Sbjct: 665 LLLLFLFIIIFSLLGMQLFGGK--FNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVM 722
Query: 551 YVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLL 652
Y YG PS G VC+ II LF+ G +LL
Sbjct: 723 YDGIMAYGGPSSSGMIVCIYFII-LFICGNYILL 755
>AB209171-1|BAD92408.1| 1854|Homo sapiens calcium channel,
voltage-dependent, L type, alpha 1D subunit variant
protein.
Length = 1854
Score = 31.9 bits (69), Expect = 3.0
Identities = 33/94 (35%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Frame = +2
Query: 386 LMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALF-NGAQKLFGMV-ITVGQ---AIV 550
L+ L + I+ S L MQL G +T R+ F N Q L + I G+ A++
Sbjct: 347 LLLLFLFIIIFSLLGMQLFGGK--FNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVM 404
Query: 551 YVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLL 652
Y YG PS G VC+ II LF+ G +LL
Sbjct: 405 YDGIMAYGGPSSSGMIVCIYFII-LFICGNYILL 437
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 125,714,846
Number of Sequences: 237096
Number of extensions: 2841282
Number of successful extensions: 5823
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5562
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5805
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10649685938
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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