Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP03_FL5_O05
(901 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein. 197 4e-50
M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene ... 196 9e-50
M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase p... 196 9e-50
BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle... 196 9e-50
BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein. 196 9e-50
BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle... 196 9e-50
BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle... 196 9e-50
BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle... 196 9e-50
BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle... 196 9e-50
AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle... 196 9e-50
AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isofo... 196 9e-50
X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein. 193 6e-49
M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein. 192 1e-48
U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L isoe... 191 3e-48
U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R isoe... 191 3e-48
BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver ... 191 3e-48
AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver ... 191 3e-48
AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver... 191 3e-48
AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver... 191 3e-48
AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein. 191 3e-48
D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein. 188 2e-47
S60712-1|AAB26262.1| 67|Homo sapiens R-type pyruvate kinase pr... 109 2e-23
AF025439-1|AAC39559.1| 164|Homo sapiens Opa-interacting protein... 50 1e-05
Z98885-6|CAO72062.1| 509|Homo sapiens bromodomain containing 1 ... 35 0.46
AB209216-1|BAD92453.1| 471|Homo sapiens bromodomain containing ... 35 0.46
AM260536-1|CAJ97431.1| 1266|Homo sapiens ponsin protein. 34 0.61
AL158165-7|CAI14379.1| 1292|Homo sapiens sorbin and SH3 domain c... 34 0.61
AF356525-1|AAK37563.1| 1292|Homo sapiens sorbin and SH3 domain c... 34 0.61
AL121747-11|CAO03633.1| 340|Homo sapiens RanBP-type and C3HC4-t... 31 5.7
U08377-1|AAA19604.1| 951|Homo sapiens protein ( Human homolog o... 31 7.5
BC024041-1|AAH24041.1| 547|Homo sapiens SFRS8 protein protein. 31 7.5
BC015953-1|AAH15953.1| 760|Homo sapiens SFRS8 protein protein. 31 7.5
BC008707-1|AAH08707.1| 760|Homo sapiens SFRS8 protein protein. 31 7.5
AK125451-1|BAC86167.1| 221|Homo sapiens protein ( Homo sapiens ... 31 7.5
AB208921-1|BAD92158.1| 636|Homo sapiens SFRS8 protein variant p... 31 7.5
U77629-1|AAB86993.1| 193|Homo sapiens Achaete-Scute homologue 2... 30 10.0
BX538020-1|CAD97966.1| 1510|Homo sapiens hypothetical protein pr... 30 10.0
BC057801-1|AAH57801.2| 193|Homo sapiens achaete-scute complex h... 30 10.0
AF442769-2|AAL35362.1| 193|Homo sapiens achaete-scute-like 2 pr... 30 10.0
AB023164-1|BAA76791.3| 2330|Homo sapiens KIAA0947 protein protein. 30 10.0
>BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein.
Length = 366
Score = 197 bits (481), Expect = 4e-50
Identities = 93/119 (78%), Positives = 103/119 (86%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 116 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 175
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLV 610
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA ++HR+LF +LV
Sbjct: 176 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELV 234
Score = 119 bits (286), Expect = 2e-26
Identities = 56/76 (73%), Positives = 64/76 (84%)
Frame = +1
Query: 25 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN 204
S+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +LGEKGKN
Sbjct: 40 SKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKN 99
Query: 205 IKIISKIENHQGNGQF 252
IKIISKIENH+G +F
Sbjct: 100 IKIISKIENHEGVRRF 115
Score = 52.8 bits (121), Expect = 2e-06
Identities = 26/74 (35%), Positives = 40/74 (54%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KCLA+A++V+T SG+SAH +++YRPR + G+ P++
Sbjct: 252 VEASYKCLAAALIVLTESGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 310
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 311 DPVQEAWAEDVDLR 324
>M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene
encoding cytosolic thyroid hormone-binding protein,
complete cds. ).
Length = 531
Score = 196 bits (478), Expect = 9e-50
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 281 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 340
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 341 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 398
Score = 130 bits (313), Expect = 9e-30
Identities = 61/82 (74%), Positives = 69/82 (84%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +L
Sbjct: 199 NGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVL 258
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 259 GEKGKNIKIISKIENHEGVRRF 280
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 417 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 475
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 476 DPVQEAWAEDVDLR 489
>M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase
protein.
Length = 531
Score = 196 bits (478), Expect = 9e-50
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 281 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 340
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 341 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQNLIAREAEAAIYHLQLFEEL 398
Score = 130 bits (313), Expect = 9e-30
Identities = 61/82 (74%), Positives = 69/82 (84%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +L
Sbjct: 199 NGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVL 258
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 259 GEKGKNIKIISKIENHEGVRRF 280
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 417 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 475
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 476 DPVQEAWAEDVDLR 489
>BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 196 bits (478), Expect = 9e-50
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 281 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 340
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 341 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 398
Score = 126 bits (304), Expect = 1e-28
Identities = 60/82 (73%), Positives = 68/82 (82%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG L S+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +L
Sbjct: 199 NGGSLVSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVL 258
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 259 GEKGKNIKIISKIENHEGVRRF 280
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 417 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 475
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 476 DPVQEAWAEDVDLR 489
>BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein.
Length = 343
Score = 196 bits (478), Expect = 9e-50
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 93 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 152
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 153 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 210
Score = 130 bits (313), Expect = 9e-30
Identities = 61/82 (74%), Positives = 69/82 (84%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +L
Sbjct: 11 NGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVL 70
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 71 GEKGKNIKIISKIENHEGVRRF 92
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 229 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 287
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 288 DPVQEAWAEDVDLR 301
>BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 196 bits (478), Expect = 9e-50
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 281 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 340
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 341 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 398
Score = 130 bits (313), Expect = 9e-30
Identities = 61/82 (74%), Positives = 69/82 (84%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +L
Sbjct: 199 NGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVL 258
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 259 GEKGKNIKIISKIENHEGVRRF 280
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 417 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 475
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 476 DPVQEAWAEDVDLR 489
>BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 196 bits (478), Expect = 9e-50
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 281 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 340
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 341 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 398
Score = 130 bits (313), Expect = 9e-30
Identities = 61/82 (74%), Positives = 69/82 (84%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +L
Sbjct: 199 NGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVL 258
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 259 GEKGKNIKIISKIENHEGVRRF 280
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 417 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 475
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 476 DPVQEAWAEDVDLR 489
>BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 196 bits (478), Expect = 9e-50
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 281 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 340
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 341 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 398
Score = 130 bits (313), Expect = 9e-30
Identities = 61/82 (74%), Positives = 69/82 (84%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +L
Sbjct: 199 NGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVL 258
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 259 GEKGKNIKIISKIENHEGVRRF 280
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 417 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 475
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 476 DPVQEAWAEDVDLR 489
>BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 196 bits (478), Expect = 9e-50
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 281 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 340
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 341 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 398
Score = 130 bits (313), Expect = 9e-30
Identities = 61/82 (74%), Positives = 69/82 (84%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +L
Sbjct: 199 NGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVL 258
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 259 GEKGKNIKIISKIENHEGVRRF 280
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 417 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 475
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 476 DPVQEAWAEDVDLR 489
>AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 196 bits (478), Expect = 9e-50
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 281 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 340
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 341 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 398
Score = 130 bits (313), Expect = 9e-30
Identities = 61/82 (74%), Positives = 69/82 (84%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +L
Sbjct: 199 NGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVL 258
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 259 GEKGKNIKIISKIENHEGVRRF 280
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 417 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 475
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 476 DPVQEAWAEDVDLR 489
>AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isoform
1 variant protein.
Length = 531
Score = 196 bits (478), Expect = 9e-50
Identities = 93/118 (78%), Positives = 101/118 (85%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPRP
Sbjct: 281 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRP 340
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 341 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 398
Score = 126 bits (305), Expect = 8e-29
Identities = 60/82 (73%), Positives = 68/82 (82%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + + E+R +L
Sbjct: 199 NGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVREVRKVL 258
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 259 GEKGKNIKIISKIENHEGVRRF 280
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 417 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 475
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 476 DPVQEAWAEDVDLR 489
>X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein.
Length = 531
Score = 193 bits (471), Expect = 6e-49
Identities = 92/118 (77%), Positives = 100/118 (84%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKP P
Sbjct: 281 DEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPPP 340
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKGDYP+E V I +EAEA I+H QLF +L
Sbjct: 341 TRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 398
Score = 130 bits (313), Expect = 9e-30
Identities = 61/82 (74%), Positives = 69/82 (84%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG LGS+KGVNLPG VDLPAVSEKD DL FGVEQ VDM+FASFIR + +HE+R +L
Sbjct: 199 NGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVL 258
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
GEKGKNIKIISKIENH+G +F
Sbjct: 259 GEKGKNIKIISKIENHEGVRRF 280
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 417 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 475
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 476 DPVQEAWAEDVDLR 489
>M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein.
Length = 543
Score = 192 bits (468), Expect = 1e-48
Identities = 89/118 (75%), Positives = 100/118 (84%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPRP
Sbjct: 293 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRP 352
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKG++PVE V I +EAEA ++HRQLF +L
Sbjct: 353 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHRIAREAEAAVYHRQLFEEL 410
Score = 110 bits (264), Expect = 8e-24
Identities = 51/82 (62%), Positives = 63/82 (76%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG+LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R L
Sbjct: 211 NGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAAL 270
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
G +G IKIISKIENH+G +F
Sbjct: 271 GPEGHGIKIISKIENHEGVKRF 292
Score = 63.7 bits (148), Expect = 9e-10
Identities = 33/79 (41%), Positives = 44/79 (55%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEAA KC A+AI+V+TT+G+SA LLS+YRPR + GV P++Y
Sbjct: 429 VEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRA-AVIAVTRSAQAARQVHLCRGVFPLLYR 487
Query: 843 XPTASDWLKDXDNRXQXGL 899
P + W D D R Q G+
Sbjct: 488 EPPEAIWADDVDRRVQFGI 506
>U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L
isoenzyme protein.
Length = 566
Score = 191 bits (466), Expect = 3e-48
Identities = 89/118 (75%), Positives = 100/118 (84%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPRP
Sbjct: 316 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRP 375
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKG++PVE V I +EAEA ++HRQLF +L
Sbjct: 376 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEEL 433
Score = 110 bits (264), Expect = 8e-24
Identities = 51/82 (62%), Positives = 63/82 (76%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG+LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R L
Sbjct: 234 NGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAAL 293
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
G +G IKIISKIENH+G +F
Sbjct: 294 GPEGHGIKIISKIENHEGVKRF 315
Score = 63.7 bits (148), Expect = 9e-10
Identities = 33/79 (41%), Positives = 44/79 (55%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEAA KC A+AI+V+TT+G+SA LLS+YRPR + GV P++Y
Sbjct: 452 VEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRA-AVIAVTRSAQAARQVHLCRGVFPLLYR 510
Query: 843 XPTASDWLKDXDNRXQXGL 899
P + W D D R Q G+
Sbjct: 511 EPPEAIWADDVDRRVQFGI 529
>U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R
isoenzyme protein.
Length = 587
Score = 191 bits (466), Expect = 3e-48
Identities = 89/118 (75%), Positives = 100/118 (84%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPRP
Sbjct: 337 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRP 396
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKG++PVE V I +EAEA ++HRQLF +L
Sbjct: 397 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEEL 454
Score = 110 bits (264), Expect = 8e-24
Identities = 51/82 (62%), Positives = 63/82 (76%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG+LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R L
Sbjct: 255 NGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAAL 314
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
G +G IKIISKIENH+G +F
Sbjct: 315 GPEGHGIKIISKIENHEGVKRF 336
Score = 63.7 bits (148), Expect = 9e-10
Identities = 33/79 (41%), Positives = 44/79 (55%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEAA KC A+AI+V+TT+G+SA LLS+YRPR + GV P++Y
Sbjct: 473 VEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRA-AVIAVTRSAQAARQVHLCRGVFPLLYR 531
Query: 843 XPTASDWLKDXDNRXQXGL 899
P + W D D R Q G+
Sbjct: 532 EPPEAIWADDVDRRVQFGI 550
>BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 191 bits (466), Expect = 3e-48
Identities = 89/118 (75%), Positives = 100/118 (84%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPRP
Sbjct: 324 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRP 383
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKG++PVE V I +EAEA ++HRQLF +L
Sbjct: 384 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEEL 441
Score = 110 bits (264), Expect = 8e-24
Identities = 51/82 (62%), Positives = 63/82 (76%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG+LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R L
Sbjct: 242 NGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAAL 301
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
G +G IKIISKIENH+G +F
Sbjct: 302 GPEGHGIKIISKIENHEGVKRF 323
Score = 63.7 bits (148), Expect = 9e-10
Identities = 33/79 (41%), Positives = 44/79 (55%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEAA KC A+AI+V+TT+G+SA LLS+YRPR + GV P++Y
Sbjct: 460 VEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRA-AVIAVTRSAQAARQVHLCRGVFPLLYR 518
Query: 843 XPTASDWLKDXDNRXQXGL 899
P + W D D R Q G+
Sbjct: 519 EPPEAIWADDVDRRVQFGI 537
>AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 191 bits (466), Expect = 3e-48
Identities = 89/118 (75%), Positives = 100/118 (84%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPRP
Sbjct: 324 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRP 383
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKG++PVE V I +EAEA ++HRQLF +L
Sbjct: 384 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEEL 441
Score = 110 bits (264), Expect = 8e-24
Identities = 51/82 (62%), Positives = 63/82 (76%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG+LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R L
Sbjct: 242 NGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAAL 301
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
G +G IKIISKIENH+G +F
Sbjct: 302 GPEGHGIKIISKIENHEGVKRF 323
Score = 63.7 bits (148), Expect = 9e-10
Identities = 33/79 (41%), Positives = 44/79 (55%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEAA KC A+AI+V+TT+G+SA LLS+YRPR + GV P++Y
Sbjct: 460 VEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRA-AVIAVTRSAQAARQVHLCRGVFPLLYR 518
Query: 843 XPTASDWLKDXDNRXQXGL 899
P + W D D R Q G+
Sbjct: 519 EPPEAIWADDVDRRVQFGI 537
>AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 585
Score = 191 bits (466), Expect = 3e-48
Identities = 89/118 (75%), Positives = 100/118 (84%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPRP
Sbjct: 335 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRP 394
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKG++PVE V I +EAEA ++HRQLF +L
Sbjct: 395 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEEL 452
Score = 110 bits (264), Expect = 8e-24
Identities = 51/82 (62%), Positives = 63/82 (76%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG+LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R L
Sbjct: 253 NGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAAL 312
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
G +G IKIISKIENH+G +F
Sbjct: 313 GPEGHGIKIISKIENHEGVKRF 334
Score = 63.7 bits (148), Expect = 9e-10
Identities = 33/79 (41%), Positives = 44/79 (55%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEAA KC A+AI+V+TT+G+SA LLS+YRPR + GV P++Y
Sbjct: 471 VEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRA-AVIAVTRSAQAARQVHLCRGVFPLLYR 529
Query: 843 XPTASDWLKDXDNRXQXGL 899
P + W D D R Q G+
Sbjct: 530 EPPEAIWADDVDRRVQFGI 548
>AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 565
Score = 191 bits (466), Expect = 3e-48
Identities = 89/118 (75%), Positives = 100/118 (84%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPRP
Sbjct: 315 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRP 374
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKG++PVE V I +EAEA ++HRQLF +L
Sbjct: 375 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEEL 432
Score = 110 bits (264), Expect = 8e-24
Identities = 51/82 (62%), Positives = 63/82 (76%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG+LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R L
Sbjct: 233 NGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAAL 292
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
G +G IKIISKIENH+G +F
Sbjct: 293 GPEGHGIKIISKIENHEGVKRF 314
Score = 63.7 bits (148), Expect = 9e-10
Identities = 33/79 (41%), Positives = 44/79 (55%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEAA KC A+AI+V+TT+G+SA LLS+YRPR + GV P++Y
Sbjct: 451 VEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRA-AVIAVTRSAQAARQVHLCRGVFPLLYR 509
Query: 843 XPTASDWLKDXDNRXQXGL 899
P + W D D R Q G+
Sbjct: 510 EPPEAIWADDVDRRVQFGI 528
>AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein.
Length = 574
Score = 191 bits (466), Expect = 3e-48
Identities = 89/118 (75%), Positives = 100/118 (84%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPRP
Sbjct: 324 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRP 383
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKG++PVE V I +EAEA ++HRQLF +L
Sbjct: 384 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEEL 441
Score = 110 bits (264), Expect = 8e-24
Identities = 51/82 (62%), Positives = 63/82 (76%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG+LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R L
Sbjct: 242 NGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAAL 301
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
G +G IKIISKIENH+G +F
Sbjct: 302 GPEGHGIKIISKIENHEGVKRF 323
Score = 63.7 bits (148), Expect = 9e-10
Identities = 33/79 (41%), Positives = 44/79 (55%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEAA KC A+AI+V+TT+G+SA LLS+YRPR + GV P++Y
Sbjct: 460 VEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRA-AVIAVTRSAQAARQVHLCRGVFPLLYR 518
Query: 843 XPTASDWLKDXDNRXQXGL 899
P + W D D R Q G+
Sbjct: 519 EPPEAIWADDVDRRVQFGI 537
>D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein.
Length = 599
Score = 188 bits (458), Expect = 2e-47
Identities = 88/118 (74%), Positives = 99/118 (83%)
Frame = +2
Query: 254 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 433
DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ K RP
Sbjct: 349 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARP 408
Query: 434 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
TRAE SDVANA+LDGADC+MLSGETAKG++PVE V I +EAEA ++HRQLF +L
Sbjct: 409 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEEL 466
Score = 110 bits (264), Expect = 8e-24
Identities = 51/82 (62%), Positives = 63/82 (76%)
Frame = +1
Query: 7 NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 186
NGG+LGSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R L
Sbjct: 267 NGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAAL 326
Query: 187 GEKGKNIKIISKIENHQGNGQF 252
G +G IKIISKIENH+G +F
Sbjct: 327 GPEGHGIKIISKIENHEGVKRF 348
Score = 63.7 bits (148), Expect = 9e-10
Identities = 33/79 (41%), Positives = 44/79 (55%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEAA KC A+AI+V+TT+G+SA LLS+YRPR + GV P++Y
Sbjct: 485 VEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRA-AVIAVTRSAQAARQVHLCRGVFPLLYR 543
Query: 843 XPTASDWLKDXDNRXQXGL 899
P + W D D R Q G+
Sbjct: 544 EPPEAIWADDVDRRVQFGI 562
>S60712-1|AAB26262.1| 67|Homo sapiens R-type pyruvate kinase
protein.
Length = 67
Score = 109 bits (261), Expect = 2e-23
Identities = 50/66 (75%), Positives = 56/66 (84%)
Frame = +2
Query: 377 KPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANI 556
KPV CATQMLESM+ KPRPTRAE SDVANA+LDGADC+MLSGETAKG++PVE V I
Sbjct: 1 KPVFCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAI 60
Query: 557 CKEAEA 574
+EAEA
Sbjct: 61 AREAEA 66
>AF025439-1|AAC39559.1| 164|Homo sapiens Opa-interacting protein
OIP3 protein.
Length = 164
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/74 (33%), Positives = 38/74 (51%)
Frame = +3
Query: 663 VEAATKCLASAIVVITTSGKSAHLLSKYRPRCXXXXXXXXXXXXXXRCTSTGGVLPIVYX 842
VEA+ KC + AI+V+T SG+SAH +++YRPR + G+ P++
Sbjct: 50 VEASFKCCSGAIIVLTKSGRSAHQVARYRPRA-PIIAVTRNPQTARQAHLYRGIFPVLCK 108
Query: 843 XPTASDWLKDXDNR 884
P W +D D R
Sbjct: 109 DPVQEAWAEDVDLR 122
Score = 39.1 bits (87), Expect = 0.021
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +2
Query: 515 GDYPVECVHTMANICKEAEAVIWHRQLFNDL 607
GDYP+E V I +EAEA I+H QLF +L
Sbjct: 1 GDYPLEAVRMQHLIAREAEAAIYHLQLFEEL 31
>Z98885-6|CAO72062.1| 509|Homo sapiens bromodomain containing 1
protein.
Length = 509
Score = 34.7 bits (76), Expect = 0.46
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Frame = -3
Query: 788 CGCLVXGDDGAARPVLAEQVRRLAARRDDHDGRRQALGGRLHPRRWRPSARDRSAASPRT 609
C GD AA+ +AE +RRL R R+A G R H R W R + P
Sbjct: 427 CSPSEVGDSSAAKEKVAEHMRRL---RGGGGVPRKAPGRRSHQRLWGCEERAGAGRRPGE 483
Query: 608 QGH-*RVACARLQ 573
+GH C R+Q
Sbjct: 484 EGHTPTTLCLRVQ 496
>AB209216-1|BAD92453.1| 471|Homo sapiens bromodomain containing
protein 1 variant protein.
Length = 471
Score = 34.7 bits (76), Expect = 0.46
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Frame = -3
Query: 788 CGCLVXGDDGAARPVLAEQVRRLAARRDDHDGRRQALGGRLHPRRWRPSARDRSAASPRT 609
C GD AA+ +AE +RRL R R+A G R H R W R + P
Sbjct: 389 CSPSEVGDSSAAKEKVAEHMRRL---RGGGGVPRKAPGRRSHQRLWGCEERAGAGRRPGE 445
Query: 608 QGH-*RVACARLQ 573
+GH C R+Q
Sbjct: 446 EGHTPTTLCLRVQ 458
>AM260536-1|CAJ97431.1| 1266|Homo sapiens ponsin protein.
Length = 1266
Score = 34.3 bits (75), Expect = 0.61
Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 7/73 (9%)
Frame = -3
Query: 206 MFLPFSPRMPRISCSAAPLRMNDAKIIS-TPCSTPKSRSDLS------FSETAGRSTGMP 48
M LPFS P S +A+P + +K+I+ P S P SR LS SE + G+P
Sbjct: 892 MDLPFSSS-PSRSATASPQFSSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVGVP 950
Query: 47 GRLTPFRDPSIPP 9
GR + P +PP
Sbjct: 951 GRRSLALTPPLPP 963
>AL158165-7|CAI14379.1| 1292|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 1292
Score = 34.3 bits (75), Expect = 0.61
Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 7/73 (9%)
Frame = -3
Query: 206 MFLPFSPRMPRISCSAAPLRMNDAKIIS-TPCSTPKSRSDLS------FSETAGRSTGMP 48
M LPFS P S +A+P + +K+I+ P S P SR LS SE + G+P
Sbjct: 938 MDLPFSSS-PSRSATASPQFSSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVGVP 996
Query: 47 GRLTPFRDPSIPP 9
GR + P +PP
Sbjct: 997 GRRSLALTPPLPP 1009
>AF356525-1|AAK37563.1| 1292|Homo sapiens sorbin and SH3 domain
containing 1 protein.
Length = 1292
Score = 34.3 bits (75), Expect = 0.61
Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 7/73 (9%)
Frame = -3
Query: 206 MFLPFSPRMPRISCSAAPLRMNDAKIIS-TPCSTPKSRSDLS------FSETAGRSTGMP 48
M LPFS P S +A+P + +K+I+ P S P SR LS SE + G+P
Sbjct: 938 MDLPFSSS-PSRSATASPQFSSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVGVP 996
Query: 47 GRLTPFRDPSIPP 9
GR + P +PP
Sbjct: 997 GRRSLALTPPLPP 1009
>AL121747-11|CAO03633.1| 340|Homo sapiens RanBP-type and C3HC4-type
zinc finger containing 1 protein.
Length = 340
Score = 31.1 bits (67), Expect = 5.7
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = -3
Query: 668 LHPRRWRPSARDR-SAASPRTQGH*RVACARLQLQPPCKCWPWCEHTRQDSRPWQSPRR 495
L P RW SA S+ SPR V CA + P + P TR+ R W++ RR
Sbjct: 74 LSPHRWAGSAPGAPSSTSPRGLA---VRCAAGRAPRPTRSPPHTSPTRRSERAWRARRR 129
>U08377-1|AAA19604.1| 951|Homo sapiens protein ( Human homolog of
Drosophila splicing regulator
suppressor-of-white-apricot mRNA, complete cds. ).
Length = 951
Score = 30.7 bits (66), Expect = 7.5
Identities = 14/37 (37%), Positives = 19/37 (51%)
Frame = +2
Query: 5 GTEVCSDPGKASTCPAYPWTYPQSPRRTSRTCSSASN 115
G V + PG +T P P T P P T+ T S A++
Sbjct: 399 GVTVSNSPGVTTTAPPPPGTTPPPPPTTAETSSGATS 435
>BC024041-1|AAH24041.1| 547|Homo sapiens SFRS8 protein protein.
Length = 547
Score = 30.7 bits (66), Expect = 7.5
Identities = 14/37 (37%), Positives = 19/37 (51%)
Frame = +2
Query: 5 GTEVCSDPGKASTCPAYPWTYPQSPRRTSRTCSSASN 115
G V + PG +T P P T P P T+ T S A++
Sbjct: 336 GVTVSNSPGVTTTAPPPPGTTPPPPPTTAETSSGATS 372
>BC015953-1|AAH15953.1| 760|Homo sapiens SFRS8 protein protein.
Length = 760
Score = 30.7 bits (66), Expect = 7.5
Identities = 14/37 (37%), Positives = 19/37 (51%)
Frame = +2
Query: 5 GTEVCSDPGKASTCPAYPWTYPQSPRRTSRTCSSASN 115
G V + PG +T P P T P P T+ T S A++
Sbjct: 399 GVTVSNSPGVTTTAPPPPGTTPPPPPTTAETSSGATS 435
>BC008707-1|AAH08707.1| 760|Homo sapiens SFRS8 protein protein.
Length = 760
Score = 30.7 bits (66), Expect = 7.5
Identities = 14/37 (37%), Positives = 19/37 (51%)
Frame = +2
Query: 5 GTEVCSDPGKASTCPAYPWTYPQSPRRTSRTCSSASN 115
G V + PG +T P P T P P T+ T S A++
Sbjct: 399 GVTVSNSPGVTTTAPPPPGTTPPPPPTTAETSSGATS 435
>AK125451-1|BAC86167.1| 221|Homo sapiens protein ( Homo sapiens
cDNA FLJ43462 fis, clone OCBBF2035916. ).
Length = 221
Score = 30.7 bits (66), Expect = 7.5
Identities = 13/28 (46%), Positives = 16/28 (57%)
Frame = -3
Query: 416 PWIPAFESHRSLVFQPDCIWRSWSSGRG 333
PW PA E+ RS + C R+W SG G
Sbjct: 180 PWGPALEADRSTGLRMSCCPRTWWSGPG 207
>AB208921-1|BAD92158.1| 636|Homo sapiens SFRS8 protein variant
protein.
Length = 636
Score = 30.7 bits (66), Expect = 7.5
Identities = 14/37 (37%), Positives = 19/37 (51%)
Frame = +2
Query: 5 GTEVCSDPGKASTCPAYPWTYPQSPRRTSRTCSSASN 115
G V + PG +T P P T P P T+ T S A++
Sbjct: 283 GVTVSNSPGVTTTAPPPPGTTPPPPPTTAETSSGATS 319
>U77629-1|AAB86993.1| 193|Homo sapiens Achaete-Scute homologue 2
protein.
Length = 193
Score = 30.3 bits (65), Expect = 10.0
Identities = 15/33 (45%), Positives = 18/33 (54%)
Frame = -3
Query: 737 EQVRRLAARRDDHDGRRQALGGRLHPRRWRPSA 639
E +R L +HD R AL G L P+ RPSA
Sbjct: 97 EYIRALQRLLAEHDAVRNALAGGLRPQAVRPSA 129
>BX538020-1|CAD97966.1| 1510|Homo sapiens hypothetical protein
protein.
Length = 1510
Score = 30.3 bits (65), Expect = 10.0
Identities = 14/43 (32%), Positives = 23/43 (53%)
Frame = -3
Query: 137 AKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTPFRDPSIPP 9
A +I+TP T + S L S + G+++PFR+ +PP
Sbjct: 881 APLIATPPRTSQPLSPLISSSSPSSPASPVGQVSPFRETPVPP 923
>BC057801-1|AAH57801.2| 193|Homo sapiens achaete-scute complex
homolog 2 (Drosophila) protein.
Length = 193
Score = 30.3 bits (65), Expect = 10.0
Identities = 15/33 (45%), Positives = 18/33 (54%)
Frame = -3
Query: 737 EQVRRLAARRDDHDGRRQALGGRLHPRRWRPSA 639
E +R L +HD R AL G L P+ RPSA
Sbjct: 97 EYIRALQRLLAEHDAVRNALAGGLRPQAVRPSA 129
>AF442769-2|AAL35362.1| 193|Homo sapiens achaete-scute-like 2
protein.
Length = 193
Score = 30.3 bits (65), Expect = 10.0
Identities = 15/33 (45%), Positives = 18/33 (54%)
Frame = -3
Query: 737 EQVRRLAARRDDHDGRRQALGGRLHPRRWRPSA 639
E +R L +HD R AL G L P+ RPSA
Sbjct: 97 EYIRALQRLLAEHDAVRNALAGGLRPQAVRPSA 129
>AB023164-1|BAA76791.3| 2330|Homo sapiens KIAA0947 protein protein.
Length = 2330
Score = 30.3 bits (65), Expect = 10.0
Identities = 14/43 (32%), Positives = 23/43 (53%)
Frame = -3
Query: 137 AKIISTPCSTPKSRSDLSFSETAGRSTGMPGRLTPFRDPSIPP 9
A +I+TP T + S L S + G+++PFR+ +PP
Sbjct: 1701 APLIATPPRTSQPLSPLISSSSPSSPASPVGQVSPFRETPVPP 1743
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 129,042,906
Number of Sequences: 237096
Number of extensions: 2853508
Number of successful extensions: 9344
Number of sequences better than 10.0: 40
Number of HSP's better than 10.0 without gapping: 8482
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9322
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11603768198
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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