Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP03_FL5_I01
(820 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 162 1e-39
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 162 1e-39
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 162 1e-39
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 162 1e-39
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 162 1e-39
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 162 1e-39
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 162 1e-39
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 162 1e-39
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 162 1e-39
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 162 1e-39
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 162 1e-39
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 162 1e-39
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 162 1e-39
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 162 1e-39
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 162 1e-39
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 155 1e-37
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 155 1e-37
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 155 1e-37
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 155 1e-37
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 155 1e-37
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 153 1e-36
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 145 2e-34
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 145 2e-34
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 145 2e-34
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 145 2e-34
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 145 2e-34
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 145 2e-34
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 145 2e-34
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 145 2e-34
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 145 2e-34
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 141 3e-33
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 141 3e-33
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 141 3e-33
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 141 3e-33
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 141 3e-33
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 141 3e-33
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 120 5e-27
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 120 8e-27
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 120 8e-27
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 120 8e-27
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 120 8e-27
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 120 8e-27
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 120 8e-27
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 120 8e-27
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 120 8e-27
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 120 8e-27
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 120 8e-27
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 120 8e-27
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 118 3e-26
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 118 3e-26
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 118 3e-26
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 118 3e-26
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 118 3e-26
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 118 3e-26
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 118 3e-26
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 118 3e-26
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 118 3e-26
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 117 4e-26
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 117 4e-26
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 117 4e-26
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 117 4e-26
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 117 4e-26
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 117 4e-26
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 117 4e-26
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 117 4e-26
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 117 4e-26
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 117 4e-26
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 115 2e-25
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 115 2e-25
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 115 2e-25
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 115 2e-25
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 115 2e-25
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 115 2e-25
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 115 2e-25
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 115 2e-25
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 115 2e-25
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 115 2e-25
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 115 2e-25
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 114 3e-25
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 113 7e-25
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 113 7e-25
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 112 2e-24
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 112 2e-24
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 111 2e-24
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 111 2e-24
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 111 2e-24
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 111 3e-24
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 110 5e-24
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 110 5e-24
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 82 2e-15
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 54 6e-07
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 45 3e-04
U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit... 36 0.13
CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein. 36 0.13
BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated... 36 0.13
BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated... 36 0.13
BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein. 36 0.13
AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated... 36 0.13
AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated... 36 0.13
AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated... 36 0.13
AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated... 36 0.13
AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens ... 36 0.13
AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta ... 36 0.13
AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta ... 36 0.13
X83127-1|CAA58208.1| 401|Homo sapiens voltage gated potassium c... 36 0.23
U33428-1|AAC50953.1| 401|Homo sapiens K+ channel beta 1a subuni... 36 0.23
U16953-1|AAC50122.1| 408|Homo sapiens potassium channel beta3 s... 36 0.23
L47665-1|AAC41926.1| 419|Homo sapiens K+ channel beta-subunit p... 36 0.23
L39833-1|AAC37573.1| 408|Homo sapiens K+ channel beta-subunit p... 36 0.23
BC043166-1|AAH43166.1| 401|Homo sapiens potassium voltage-gated... 36 0.23
CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein. 34 0.71
BC043183-1|AAH43183.1| 1284|Homo sapiens collagen, type XX, alph... 33 1.6
AB040943-1|BAA96034.1| 1140|Homo sapiens KIAA1510 protein protein. 33 1.6
AY780786-1|AAV98356.1| 372|Homo sapiens potassium voltage-gated... 32 2.9
BC111958-1|AAI11959.1| 710|Homo sapiens ral guanine nucleotide ... 31 5.0
BC101756-1|AAI01757.1| 710|Homo sapiens ral guanine nucleotide ... 31 5.0
AK074082-1|BAB84908.1| 497|Homo sapiens FLJ00153 protein protein. 31 5.0
AB038782-1|BAB12116.1| 878|Homo sapiens intestinal mucin protein. 31 5.0
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 31 6.6
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 30 8.8
U72619-1|AAB61992.1| 22|Homo sapiens aldose reductase protein. 30 8.8
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 30 8.8
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 30 8.8
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 30 8.8
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 30 8.8
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 30 8.8
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 30 8.8
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 30 8.8
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 30 8.8
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 61.3 bits (142), Expect = 4e-09
Identities = 32/66 (48%), Positives = 42/66 (63%)
Frame = +1
Query: 469 GPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLL 648
G +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +L
Sbjct: 115 GFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMIL 171
Query: 649 XHATVK 666
+K
Sbjct: 172 NKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 64.5 bits (150), Expect = 4e-10
Identities = 34/67 (50%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG RP KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFRPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LSKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 113
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 114 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170
Query: 646 LXHATVK 666
L +K
Sbjct: 171 LNKPGLK 177
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 162 bits (394), Expect = 1e-39
Identities = 73/106 (68%), Positives = 85/106 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 335
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 5 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 64
Query: 336 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP
Sbjct: 65 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWP 110
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/67 (49%), Positives = 43/67 (64%)
Frame = +1
Query: 466 TGPRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERL 645
TG +P KE FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN +E +
Sbjct: 111 TGFKPGKE---FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 167
Query: 646 LXHATVK 666
L +K
Sbjct: 168 LNKPGLK 174
Score = 48.8 bits (111), Expect = 2e-05
Identities = 16/32 (50%), Positives = 25/32 (78%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VNQ+ECHPYL ++L ++C++ G+ +T Y PL
Sbjct: 179 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 210
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 155 bits (377), Expect = 1e-37
Identities = 73/111 (65%), Positives = 84/111 (75%)
Frame = +3
Query: 144 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 323
FVE + + K PI+GLGTWKS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI
Sbjct: 4 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63
Query: 324 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 476
+E V REDLFI SKLW TF LVR A ++TL +L + YLD+YLIHWPQ
Sbjct: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Score = 54.4 bits (125), Expect = 5e-07
Identities = 27/65 (41%), Positives = 37/65 (56%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P+ K LFP D G ++D +AME LV EGLVK++GVSNF+ +E+LL
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 652 HATVK 666
+K
Sbjct: 173 KPGLK 177
Score = 48.4 bits (110), Expect = 3e-05
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYL ++L ++C + G+ +T Y PL
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPL 213
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 155 bits (377), Expect = 1e-37
Identities = 73/111 (65%), Positives = 84/111 (75%)
Frame = +3
Query: 144 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 323
FVE + + K PI+GLGTWKS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI
Sbjct: 4 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63
Query: 324 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 476
+E V REDLFI SKLW TF LVR A ++TL +L + YLD+YLIHWPQ
Sbjct: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Score = 54.4 bits (125), Expect = 5e-07
Identities = 27/65 (41%), Positives = 37/65 (56%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P+ K LFP D G ++D +AME LV EGLVK++GVSNF+ +E+LL
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 652 HATVK 666
+K
Sbjct: 173 KPGLK 177
Score = 48.4 bits (110), Expect = 3e-05
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYL ++L ++C + G+ +T Y PL
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPL 213
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 155 bits (377), Expect = 1e-37
Identities = 73/111 (65%), Positives = 84/111 (75%)
Frame = +3
Query: 144 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 323
FVE + + K PI+GLGTWKS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI
Sbjct: 4 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63
Query: 324 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 476
+E V REDLFI SKLW TF LVR A ++TL +L + YLD+YLIHWPQ
Sbjct: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Score = 54.4 bits (125), Expect = 5e-07
Identities = 27/65 (41%), Positives = 37/65 (56%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P+ K LFP D G ++D +AME LV EGLVK++GVSNF+ +E+LL
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 652 HATVK 666
+K
Sbjct: 173 KPGLK 177
Score = 48.4 bits (110), Expect = 3e-05
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYL ++L ++C + G+ +T Y PL
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPL 213
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 155 bits (377), Expect = 1e-37
Identities = 73/111 (65%), Positives = 84/111 (75%)
Frame = +3
Query: 144 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 323
FVE + + K PI+GLGTWKS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI
Sbjct: 4 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63
Query: 324 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 476
+E V REDLFI SKLW TF LVR A ++TL +L + YLD+YLIHWPQ
Sbjct: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Score = 54.4 bits (125), Expect = 5e-07
Identities = 27/65 (41%), Positives = 37/65 (56%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P+ K LFP D G ++D +AME LV EGLVK++GVSNF+ +E+LL
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 652 HATVK 666
+K
Sbjct: 173 KPGLK 177
Score = 48.4 bits (110), Expect = 3e-05
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYL ++L ++C + G+ +T Y PL
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPL 213
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 155 bits (377), Expect = 1e-37
Identities = 73/111 (65%), Positives = 84/111 (75%)
Frame = +3
Query: 144 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 323
FVE + + K PI+GLGTWKS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI
Sbjct: 4 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63
Query: 324 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 476
+E V REDLFI SKLW TF LVR A ++TL +L + YLD+YLIHWPQ
Sbjct: 64 QEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Score = 54.4 bits (125), Expect = 5e-07
Identities = 27/65 (41%), Positives = 37/65 (56%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P+ K LFP D G ++D +AME LV EGLVK++GVSNF+ +E+LL
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 652 HATVK 666
+K
Sbjct: 173 KPGLK 177
Score = 48.4 bits (110), Expect = 3e-05
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYL ++L ++C + G+ +T Y PL
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPL 213
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 153 bits (370), Expect = 1e-36
Identities = 72/111 (64%), Positives = 83/111 (74%)
Frame = +3
Query: 144 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 323
FVE + + K PI+GLGTWKS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI
Sbjct: 4 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKI 63
Query: 324 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 476
+E V REDLFI SKLW TF LVR A ++TL + + YLD+YLIHWPQ
Sbjct: 64 QEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQ 114
Score = 54.4 bits (125), Expect = 5e-07
Identities = 27/65 (41%), Positives = 37/65 (56%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P+ K LFP D G ++D +AME LV EGLVK++GVSNF+ +E+LL
Sbjct: 113 PQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLN 172
Query: 652 HATVK 666
+K
Sbjct: 173 KPGLK 177
Score = 48.4 bits (110), Expect = 3e-05
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYL ++L ++C + G+ +T Y PL
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPL 213
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 145 bits (351), Expect = 2e-34
Identities = 63/105 (60%), Positives = 82/105 (78%), Gaps = 1/105 (0%)
Frame = +3
Query: 168 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 344
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 345 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Score = 54.4 bits (125), Expect = 5e-07
Identities = 24/56 (42%), Positives = 38/56 (67%)
Frame = +1
Query: 502 FPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLXHATVKP 669
FP + G I + Y +T KA+E LV +GLV+++G+SNFNS ++ +L A+V+P
Sbjct: 125 FPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Score = 41.1 bits (92), Expect = 0.005
Identities = 17/32 (53%), Positives = 20/32 (62%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V QVECHPYL L C+A G+ +T Y PL
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPL 213
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 145 bits (351), Expect = 2e-34
Identities = 63/105 (60%), Positives = 82/105 (78%), Gaps = 1/105 (0%)
Frame = +3
Query: 168 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 344
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 345 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Score = 54.4 bits (125), Expect = 5e-07
Identities = 24/56 (42%), Positives = 38/56 (67%)
Frame = +1
Query: 502 FPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLXHATVKP 669
FP + G I + Y +T KA+E LV +GLV+++G+SNFNS ++ +L A+V+P
Sbjct: 125 FPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Score = 41.1 bits (92), Expect = 0.005
Identities = 17/32 (53%), Positives = 20/32 (62%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V QVECHPYL L C+A G+ +T Y PL
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPL 213
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 145 bits (351), Expect = 2e-34
Identities = 63/105 (60%), Positives = 82/105 (78%), Gaps = 1/105 (0%)
Frame = +3
Query: 168 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 344
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 345 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Score = 54.4 bits (125), Expect = 5e-07
Identities = 24/56 (42%), Positives = 38/56 (67%)
Frame = +1
Query: 502 FPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLXHATVKP 669
FP + G I + Y +T KA+E LV +GLV+++G+SNFNS ++ +L A+V+P
Sbjct: 125 FPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Score = 41.1 bits (92), Expect = 0.005
Identities = 17/32 (53%), Positives = 20/32 (62%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V QVECHPYL L C+A G+ +T Y PL
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPL 213
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 145 bits (351), Expect = 2e-34
Identities = 63/105 (60%), Positives = 82/105 (78%), Gaps = 1/105 (0%)
Frame = +3
Query: 168 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 344
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 345 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Score = 54.4 bits (125), Expect = 5e-07
Identities = 24/56 (42%), Positives = 38/56 (67%)
Frame = +1
Query: 502 FPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLXHATVKP 669
FP + G I + Y +T KA+E LV +GLV+++G+SNFNS ++ +L A+V+P
Sbjct: 125 FPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Score = 41.1 bits (92), Expect = 0.005
Identities = 17/32 (53%), Positives = 20/32 (62%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V QVECHPYL L C+A G+ +T Y PL
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPL 213
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 145 bits (351), Expect = 2e-34
Identities = 63/105 (60%), Positives = 82/105 (78%), Gaps = 1/105 (0%)
Frame = +3
Query: 168 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 344
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 345 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Score = 54.4 bits (125), Expect = 5e-07
Identities = 24/56 (42%), Positives = 38/56 (67%)
Frame = +1
Query: 502 FPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLXHATVKP 669
FP + G I + Y +T KA+E LV +GLV+++G+SNFNS ++ +L A+V+P
Sbjct: 125 FPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Score = 41.1 bits (92), Expect = 0.005
Identities = 17/32 (53%), Positives = 20/32 (62%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V QVECHPYL L C+A G+ +T Y PL
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPL 213
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 145 bits (351), Expect = 2e-34
Identities = 63/105 (60%), Positives = 82/105 (78%), Gaps = 1/105 (0%)
Frame = +3
Query: 168 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 344
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 345 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Score = 54.4 bits (125), Expect = 5e-07
Identities = 24/56 (42%), Positives = 38/56 (67%)
Frame = +1
Query: 502 FPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLXHATVKP 669
FP + G I + Y +T KA+E LV +GLV+++G+SNFNS ++ +L A+V+P
Sbjct: 125 FPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Score = 41.1 bits (92), Expect = 0.005
Identities = 17/32 (53%), Positives = 20/32 (62%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V QVECHPYL L C+A G+ +T Y PL
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPL 213
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 145 bits (351), Expect = 2e-34
Identities = 63/105 (60%), Positives = 82/105 (78%), Gaps = 1/105 (0%)
Frame = +3
Query: 168 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 344
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 345 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 145 bits (351), Expect = 2e-34
Identities = 63/105 (60%), Positives = 82/105 (78%), Gaps = 1/105 (0%)
Frame = +3
Query: 168 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 344
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 345 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Score = 54.4 bits (125), Expect = 5e-07
Identities = 24/56 (42%), Positives = 38/56 (67%)
Frame = +1
Query: 502 FPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLXHATVKP 669
FP + G I + Y +T KA+E LV +GLV+++G+SNFNS ++ +L A+V+P
Sbjct: 125 FPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Score = 41.1 bits (92), Expect = 0.005
Identities = 17/32 (53%), Positives = 20/32 (62%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V QVECHPYL L C+A G+ +T Y PL
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPL 213
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 145 bits (351), Expect = 2e-34
Identities = 63/105 (60%), Positives = 82/105 (78%), Gaps = 1/105 (0%)
Frame = +3
Query: 168 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 344
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 345 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Score = 54.4 bits (125), Expect = 5e-07
Identities = 24/56 (42%), Positives = 38/56 (67%)
Frame = +1
Query: 502 FPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLXHATVKP 669
FP + G I + Y +T KA+E LV +GLV+++G+SNFNS ++ +L A+V+P
Sbjct: 125 FPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP 180
Score = 41.1 bits (92), Expect = 0.005
Identities = 17/32 (53%), Positives = 20/32 (62%)
Frame = +2
Query: 674 VNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V QVECHPYL L C+A G+ +T Y PL
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPL 213
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 141 bits (341), Expect = 3e-33
Identities = 62/100 (62%), Positives = 75/100 (75%)
Frame = +3
Query: 174 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 353
P +GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 354 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
FI +KLW T H+ LV A +++L L + YLDLYLIHWP
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Score = 58.8 bits (136), Expect = 2e-08
Identities = 29/48 (60%), Positives = 35/48 (72%)
Frame = +1
Query: 505 PTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLL 648
P D+S + SD D++DT +AME LV GLVK+IGVSNFN LERLL
Sbjct: 134 PLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLL 181
Score = 46.4 bits (105), Expect = 1e-04
Identities = 17/33 (51%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
+ NQ+ECHPYL K L FC++ V +T Y PL
Sbjct: 191 LTNQIECHPYLTQKNLISFCQSRDVSVTAYRPL 223
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 141 bits (341), Expect = 3e-33
Identities = 62/100 (62%), Positives = 75/100 (75%)
Frame = +3
Query: 174 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 353
P +GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 354 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
FI +KLW T H+ LV A +++L L + YLDLYLIHWP
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Score = 58.8 bits (136), Expect = 2e-08
Identities = 29/48 (60%), Positives = 35/48 (72%)
Frame = +1
Query: 505 PTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLL 648
P D+S + SD D++DT +AME LV GLVK+IGVSNFN LERLL
Sbjct: 134 PLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLL 181
Score = 46.4 bits (105), Expect = 1e-04
Identities = 17/33 (51%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
+ NQ+ECHPYL K L FC++ V +T Y PL
Sbjct: 191 LTNQIECHPYLTQKNLISFCQSRDVSVTAYRPL 223
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 141 bits (341), Expect = 3e-33
Identities = 62/100 (62%), Positives = 75/100 (75%)
Frame = +3
Query: 174 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 353
P +GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 354 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
FI +KLW T H+ LV A +++L L + YLDLYLIHWP
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Score = 58.8 bits (136), Expect = 2e-08
Identities = 29/48 (60%), Positives = 35/48 (72%)
Frame = +1
Query: 505 PTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLL 648
P D+S + SD D++DT +AME LV GLVK+IGVSNFN LERLL
Sbjct: 134 PLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLL 181
Score = 46.4 bits (105), Expect = 1e-04
Identities = 17/33 (51%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
+ NQ+ECHPYL K L FC++ V +T Y PL
Sbjct: 191 LTNQIECHPYLTQKNLISFCQSRDVSVTAYRPL 223
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 141 bits (341), Expect = 3e-33
Identities = 62/100 (62%), Positives = 75/100 (75%)
Frame = +3
Query: 174 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 353
P +GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 354 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
FI +KLW T H+ LV A +++L L + YLDLYLIHWP
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 141 bits (341), Expect = 3e-33
Identities = 62/100 (62%), Positives = 75/100 (75%)
Frame = +3
Query: 174 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 353
P +GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 354 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
FI +KLW T H+ LV A +++L L + YLDLYLIHWP
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Score = 58.8 bits (136), Expect = 2e-08
Identities = 29/48 (60%), Positives = 35/48 (72%)
Frame = +1
Query: 505 PTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLL 648
P D+S + SD D++DT +AME LV GLVK+IGVSNFN LERLL
Sbjct: 134 PLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLL 181
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 141 bits (341), Expect = 3e-33
Identities = 62/100 (62%), Positives = 75/100 (75%)
Frame = +3
Query: 174 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 353
P +GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 354 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
FI +KLW T H+ LV A +++L L + YLDLYLIHWP
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWP 104
Score = 58.8 bits (136), Expect = 2e-08
Identities = 29/48 (60%), Positives = 35/48 (72%)
Frame = +1
Query: 505 PTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLL 648
P D+S + SD D++DT +AME LV GLVK+IGVSNFN LERLL
Sbjct: 134 PLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLL 181
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 120 bits (290), Expect = 5e-27
Identities = 62/114 (54%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ GY HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFP 119
Score = 53.6 bits (123), Expect = 8e-07
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 EPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 53.6 bits (123), Expect = 8e-07
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 EPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 21 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 78
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 79 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 132
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 132 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 191
Query: 652 HATVK 666
+K
Sbjct: 192 KPGLK 196
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 200 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 232
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 120 bits (288), Expect = 8e-27
Identities = 61/114 (53%), Positives = 80/114 (70%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +AVK AI+ G+ HID A+VY NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/65 (44%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 118 bits (283), Expect = 3e-26
Identities = 65/128 (50%), Positives = 86/128 (67%), Gaps = 7/128 (5%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 308
V+ N+ P+LG GT+ +SK EVT K AI+ G+RHID A++Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 309 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q- 485
I SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLYLIH P + +
Sbjct: 65 IRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 486 GRRLSLPD 509
G LS D
Sbjct: 125 GEELSPTD 132
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 118 bits (283), Expect = 3e-26
Identities = 65/128 (50%), Positives = 86/128 (67%), Gaps = 7/128 (5%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 308
V+ N+ P+LG GT+ +SK EVT K AI+ G+RHID A++Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 309 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q- 485
I SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLYLIH P + +
Sbjct: 65 IRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 486 GRRLSLPD 509
G LS D
Sbjct: 125 GEELSPTD 132
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 118 bits (283), Expect = 3e-26
Identities = 65/128 (50%), Positives = 86/128 (67%), Gaps = 7/128 (5%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 308
V+ N+ P+LG GT+ +SK EVT K AI+ G+RHID A++Y NE++VG A
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 66
Query: 309 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q- 485
I SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLYLIH P + +
Sbjct: 67 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 126
Query: 486 GRRLSLPD 509
G LS D
Sbjct: 127 GEELSPTD 134
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 121 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 180
Query: 652 HATVK 666
+K
Sbjct: 181 KPGLK 185
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 189 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 221
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (283), Expect = 3e-26
Identities = 65/128 (50%), Positives = 86/128 (67%), Gaps = 7/128 (5%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 308
V+ N+ P+LG GT+ +SK EVT K AI+ G+RHID A++Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 309 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q- 485
I SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLYLIH P + +
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 486 GRRLSLPD 509
G LS D
Sbjct: 125 GEELSPTD 132
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (283), Expect = 3e-26
Identities = 65/128 (50%), Positives = 86/128 (67%), Gaps = 7/128 (5%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 308
V+ N+ P+LG GT+ +SK EVT K AI+ G+RHID A++Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 309 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q- 485
I SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLYLIH P + +
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 486 GRRLSLPD 509
G LS D
Sbjct: 125 GEELSPTD 132
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (283), Expect = 3e-26
Identities = 65/128 (50%), Positives = 86/128 (67%), Gaps = 7/128 (5%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 308
V+ N+ P+LG GT+ +SK EVT K AI+ G+RHID A++Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 309 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q- 485
I SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLYLIH P + +
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 486 GRRLSLPD 509
G LS D
Sbjct: 125 GEELSPTD 132
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 118 bits (283), Expect = 3e-26
Identities = 65/128 (50%), Positives = 86/128 (67%), Gaps = 7/128 (5%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 308
V+ N+ P+LG GT+ +SK EVT K AI+ G+RHID A++Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 309 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q- 485
I SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLYLIH P + +
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 486 GRRLSLPD 509
G LS D
Sbjct: 125 GEELSPTD 132
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 118 bits (283), Expect = 3e-26
Identities = 65/128 (50%), Positives = 86/128 (67%), Gaps = 7/128 (5%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 308
V+ N+ P+LG GT+ +SK EVT K AI+ G+RHID A++Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 309 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q- 485
I SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLYLIH P + +
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 486 GRRLSLPD 509
G LS D
Sbjct: 125 GEELSPTD 132
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 118 bits (283), Expect = 3e-26
Identities = 65/128 (50%), Positives = 86/128 (67%), Gaps = 7/128 (5%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 308
V+ N+ P+LG GT+ +SK EVT K AI+ G+RHID A++Y NE++VG A
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVT---KLAIEAGFRHIDSAHLYNNEEQVGLA 64
Query: 309 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q- 485
I SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLYLIH P + +
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124
Query: 486 GRRLSLPD 509
G LS D
Sbjct: 125 GEELSPTD 132
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 117 bits (282), Expect = 4e-26
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 117 bits (282), Expect = 4e-26
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 117 bits (282), Expect = 4e-26
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 117 bits (282), Expect = 4e-26
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 117 bits (282), Expect = 4e-26
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 117 bits (282), Expect = 4e-26
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 117 bits (282), Expect = 4e-26
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 117 bits (282), Expect = 4e-26
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 117 bits (282), Expect = 4e-26
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 117 bits (282), Expect = 4e-26
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 119 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 219
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 115 bits (276), Expect = 2e-25
Identities = 60/106 (56%), Positives = 71/106 (66%), Gaps = 4/106 (3%)
Frame = +3
Query: 174 PILGLGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 341
PI+GLGT+ KS P G +VK AID GYRHID AY+Y NE EVGEAI KI EG V
Sbjct: 19 PIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR 78
Query: 342 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
RED+F KLW T H P++VR L+ TL L + Y+DLY+I P A
Sbjct: 79 REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/65 (38%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K ++P D++GK + + T +AME GLVKS+GVSNFN LE +L
Sbjct: 122 PMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILN 181
Query: 652 HATVK 666
+K
Sbjct: 182 KPGLK 186
Score = 43.6 bits (98), Expect = 9e-04
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY +L +FC+ + IT Y PL
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPL 222
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 115 bits (276), Expect = 2e-25
Identities = 59/123 (47%), Positives = 80/123 (65%), Gaps = 3/123 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVTQAV---KDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
VE N+ P+LG GT+ +AV K AI+ G+RHID AY+Y NE++VG AI S
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QGRRL 497
KI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLYL+H+P A +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 498 SLP 506
LP
Sbjct: 128 PLP 130
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GK+ F VD T + ME GL KSIGVSNFN LE +L
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.1 bits (92), Expect = 0.005
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYLN +L +FC++ + + + L
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 115 bits (276), Expect = 2e-25
Identities = 59/123 (47%), Positives = 80/123 (65%), Gaps = 3/123 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVTQAV---KDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
VE N+ P+LG GT+ +AV K AI+ G+RHID AY+Y NE++VG AI S
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 65
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QGRRL 497
KI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLYL+H+P A +
Sbjct: 66 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 125
Query: 498 SLP 506
LP
Sbjct: 126 PLP 128
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GK+ F VD T + ME GL KSIGVSNFN LE +L
Sbjct: 117 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILN 176
Query: 652 HATVK 666
+K
Sbjct: 177 KPGLK 181
Score = 41.1 bits (92), Expect = 0.005
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYLN +L +FC++ + + + L
Sbjct: 185 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 217
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 115 bits (276), Expect = 2e-25
Identities = 60/106 (56%), Positives = 71/106 (66%), Gaps = 4/106 (3%)
Frame = +3
Query: 174 PILGLGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 341
PI+GLGT+ KS P G +VK AID GYRHID AY+Y NE EVGEAI KI EG V
Sbjct: 19 PIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR 78
Query: 342 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
RED+F KLW T H P++VR L+ TL L + Y+DLY+I P A
Sbjct: 79 REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/65 (38%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K ++P D++GK + + T +AME GLVKS+GVSNFN LE +L
Sbjct: 122 PMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILN 181
Query: 652 HATVK 666
+K
Sbjct: 182 KPGLK 186
Score = 43.6 bits (98), Expect = 9e-04
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY +L +FC+ + IT Y PL
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPL 222
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 115 bits (276), Expect = 2e-25
Identities = 60/106 (56%), Positives = 71/106 (66%), Gaps = 4/106 (3%)
Frame = +3
Query: 174 PILGLGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 341
PI+GLGT+ KS P G +VK AID GYRHID AY+Y NE EVGEAI KI EG V
Sbjct: 19 PIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR 78
Query: 342 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
RED+F KLW T H P++VR L+ TL L + Y+DLY+I P A
Sbjct: 79 REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/65 (38%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K ++P D++GK + + T +AME GLVKS+GVSNFN LE +L
Sbjct: 122 PMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILN 181
Query: 652 HATVK 666
+K
Sbjct: 182 KPGLK 186
Score = 43.6 bits (98), Expect = 9e-04
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY +L +FC+ + IT Y PL
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPL 222
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 115 bits (276), Expect = 2e-25
Identities = 59/123 (47%), Positives = 80/123 (65%), Gaps = 3/123 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVTQAV---KDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
VE N+ P+LG GT+ +AV K AI+ G+RHID AY+Y NE++VG AI S
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QGRRL 497
KI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLYL+H+P A +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 498 SLP 506
LP
Sbjct: 128 PLP 130
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GK+ F VD T + ME GL KSIGVSNFN LE +L
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.1 bits (92), Expect = 0.005
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYLN +L +FC++ + + + L
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 115 bits (276), Expect = 2e-25
Identities = 59/123 (47%), Positives = 80/123 (65%), Gaps = 3/123 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVTQAV---KDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
VE N+ P+LG GT+ +AV K AI+ G+RHID AY+Y NE++VG AI S
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QGRRL 497
KI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLYL+H+P A +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 498 SLP 506
LP
Sbjct: 128 PLP 130
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GK+ F VD T + ME GL KSIGVSNFN LE +L
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.1 bits (92), Expect = 0.005
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYLN +L +FC++ + + + L
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 115 bits (276), Expect = 2e-25
Identities = 60/106 (56%), Positives = 71/106 (66%), Gaps = 4/106 (3%)
Frame = +3
Query: 174 PILGLGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 341
PI+GLGT+ KS P G +VK AID GYRHID AY+Y NE EVGEAI KI EG V
Sbjct: 19 PIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR 78
Query: 342 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
RED+F KLW T H P++VR L+ TL L + Y+DLY+I P A
Sbjct: 79 REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/65 (38%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K ++P D++GK + + T +AME GLVKS+GVSNFN LE +L
Sbjct: 122 PMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILN 181
Query: 652 HATVK 666
+K
Sbjct: 182 KPGLK 186
Score = 43.6 bits (98), Expect = 9e-04
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY +L +FC+ + IT Y PL
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPL 222
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 115 bits (276), Expect = 2e-25
Identities = 59/123 (47%), Positives = 80/123 (65%), Gaps = 3/123 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVTQAV---KDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
VE N+ P+LG GT+ +AV K AI+ G+RHID AY+Y NE++VG AI S
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QGRRL 497
KI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLYL+H+P A +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 498 SLP 506
LP
Sbjct: 128 PLP 130
Score = 50.4 bits (115), Expect = 8e-06
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GK+ F VD T + ME GL KSIGVSNFN LE +L
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.1 bits (92), Expect = 0.005
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYLN +L +FC++ + + + L
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 115 bits (276), Expect = 2e-25
Identities = 59/123 (47%), Positives = 80/123 (65%), Gaps = 3/123 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVTQAV---KDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
VE N+ P+LG GT+ +AV K AI+ G+RHID AY+Y NE++VG AI S
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QGRRL 497
KI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLYL+H+P A +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 498 SLP 506
LP
Sbjct: 128 PLP 130
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GK+ F VD T + ME GL KSIGVSNFN LE +L
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.1 bits (92), Expect = 0.005
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYLN +L +FC++ + + + L
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 115 bits (276), Expect = 2e-25
Identities = 59/123 (47%), Positives = 80/123 (65%), Gaps = 3/123 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVTQAV---KDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
VE N+ P+LG GT+ +AV K AI+ G+RHID AY+Y NE++VG AI S
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QGRRL 497
KI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLYL+H+P A +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 498 SLP 506
LP
Sbjct: 128 PLP 130
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GK+ F VD T + ME GL KSIGVSNFN LE +L
Sbjct: 119 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.1 bits (92), Expect = 0.005
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYLN +L +FC++ + + + L
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 219
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 114 bits (275), Expect = 3e-25
Identities = 59/114 (51%), Positives = 78/114 (68%), Gaps = 5/114 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI
Sbjct: 5 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 62
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
SKI +G V RED+F TSKLW HRP+L R AL+ +L NL + Y+DLYLIH+P
Sbjct: 63 RSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFP 116
Score = 49.2 bits (112), Expect = 2e-05
Identities = 30/69 (43%), Positives = 36/69 (52%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E L KSIGVSNFN LE +L
Sbjct: 116 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILN 175
Query: 652 HATVKPGRQ 678
KPG Q
Sbjct: 176 ----KPGLQ 180
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 184 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 216
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 113 bits (272), Expect = 7e-25
Identities = 57/104 (54%), Positives = 74/104 (71%), Gaps = 5/104 (4%)
Frame = +3
Query: 177 ILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 341
+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG AI SKI +G V
Sbjct: 1 VLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 58
Query: 342 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 59 REDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 102
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 102 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 161
Query: 652 HATVK 666
+K
Sbjct: 162 KPGLK 166
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 170 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 202
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 113 bits (272), Expect = 7e-25
Identities = 60/125 (48%), Positives = 83/125 (66%), Gaps = 4/125 (3%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVTQAV---KDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
V+ N+ P+LG GT+ ++A+ K AI+ G+RHID A++Y NE++VG AI S
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q-GRR 494
KI +G V RED+F TSKLW+T HRP+LVR AL+ +L + Y+DLYLIH P + + G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 495 LSLPD 509
LS D
Sbjct: 128 LSPTD 132
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 112 bits (269), Expect = 2e-24
Identities = 56/114 (49%), Positives = 76/114 (66%), Gaps = 3/114 (2%)
Frame = +3
Query: 174 PILGLGTWKSKPGEVTQAV---KDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 344
P+LG GT+ +AV K AI+ G+RHID AY+Y NE++VG AI SKI +G V R
Sbjct: 2 PVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKR 61
Query: 345 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QGRRLSLP 506
ED+F TSKLW TF +P +V+ AL+ +L L + Y+DLYL+H+P A + LP
Sbjct: 62 EDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLP 115
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GK+ F VD T + ME GL KSIGVSNFN LE +L
Sbjct: 104 PMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILN 163
Query: 652 HATVK 666
+K
Sbjct: 164 KPGLK 168
Score = 41.1 bits (92), Expect = 0.005
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPYLN +L +FC++ + + + L
Sbjct: 172 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL 204
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 112 bits (269), Expect = 2e-24
Identities = 61/127 (48%), Positives = 82/127 (64%), Gaps = 6/127 (4%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 311
V+ N+ P+LG GT+ P EV +A K AI+ G+RHID A++Y NE++VG A+
Sbjct: 8 VKLNDGHFMPVLGFGTYA--PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAV 65
Query: 312 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*Q-G 488
SKI +G V RED+F TSKLW HRP+LVR AL+ +L + Y+DLYLIH P + + G
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 489 RRLSLPD 509
LS D
Sbjct: 126 EELSPTD 132
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/65 (46%), Positives = 36/65 (55%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L
Sbjct: 119 PMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 652 HATVK 666
+K
Sbjct: 179 KPGLK 183
Score = 41.5 bits (93), Expect = 0.004
Identities = 15/33 (45%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N +L +FC++ + + Y L
Sbjct: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL 219
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 111 bits (268), Expect = 2e-24
Identities = 55/117 (47%), Positives = 76/117 (64%), Gaps = 3/117 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
V N+ P+LG GT+ + + +A K AID+G+RHID AY+Y NE+EVG+AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QG 488
KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL++IH P A +G
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKG 127
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 111 bits (268), Expect = 2e-24
Identities = 55/117 (47%), Positives = 76/117 (64%), Gaps = 3/117 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
V N+ P+LG GT+ + + +A K AID+G+RHID AY+Y NE+EVG+AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QG 488
KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL++IH P A +G
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKG 127
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 111 bits (268), Expect = 2e-24
Identities = 55/117 (47%), Positives = 76/117 (64%), Gaps = 3/117 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
V N+ P+LG GT+ + + +A K AID+G+RHID AY+Y NE+EVG+AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA*QG 488
KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL++IH P A +G
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKG 127
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 111 bits (267), Expect = 3e-24
Identities = 53/112 (47%), Positives = 75/112 (66%), Gaps = 3/112 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWKSKP---GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
V+ N+ PILG GT ++ V +AV+ AID+GYRHID AY + NE+ +G+AI
Sbjct: 9 VKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIRK 68
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
KI G V R+D+F T+K+W TF RP+LV+ L+ +L L + Y+DLYL H+P
Sbjct: 69 KIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFP 120
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 110 bits (265), Expect = 5e-24
Identities = 54/114 (47%), Positives = 74/114 (64%), Gaps = 3/114 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
V N+ P+LG GT+ + + +A K AID+G+RHID AY+Y NE+EVG+AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL++IH P A
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Score = 38.7 bits (86), Expect = 0.025
Identities = 14/29 (48%), Positives = 19/29 (65%)
Frame = +2
Query: 683 VECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VECHPYLN +L EFC++ + + Y L
Sbjct: 173 VECHPYLNQSKLLEFCKSKDIVLVAYSAL 201
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 110 bits (265), Expect = 5e-24
Identities = 54/114 (47%), Positives = 74/114 (64%), Gaps = 3/114 (2%)
Frame = +3
Query: 147 VEFNNELKCPILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 317
V N+ P+LG GT+ + + +A K AID+G+RHID AY+Y NE+EVG+AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 318 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL++IH P A
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Score = 38.7 bits (86), Expect = 0.025
Identities = 14/29 (48%), Positives = 19/29 (65%)
Frame = +2
Query: 683 VECHPYLNXKRLXEFCEAXGVXITXYXPL 769
VECHPYLN +L EFC++ + + Y L
Sbjct: 173 VECHPYLNQSKLLEFCKSKDIVLVAYSAL 201
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 82.2 bits (194), Expect = 2e-15
Identities = 38/60 (63%), Positives = 46/60 (76%)
Frame = +3
Query: 294 EVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
EVG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/65 (43%), Positives = 35/65 (53%)
Frame = +1
Query: 472 PRPSKEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLX 651
P K + P D++GKI F VD T +A+E GL KSIGVSNFN LE +L
Sbjct: 85 PVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILN 144
Query: 652 HATVK 666
+K
Sbjct: 145 KPGLK 149
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY N ++L +FC++ + + Y L
Sbjct: 153 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL 185
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 54.0 bits (124), Expect = 6e-07
Identities = 28/56 (50%), Positives = 34/56 (60%)
Frame = +1
Query: 499 LFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLXHATVK 666
L PTD++GK+ F VD T +AME GL KSIGVSNFN LE +L +K
Sbjct: 5 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 60
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 46.4 bits (105), Expect = 1e-04
Identities = 24/61 (39%), Positives = 34/61 (55%)
Frame = +1
Query: 484 KEDGSLFPTDQSGKIQFSDVDYVDTXKAMEPLVKEGLVKSIGVSNFNSXXLERLLXHATV 663
K ++P D++GK + + T +AME GLVKS+GVSNFN LE +L +
Sbjct: 4 KPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGL 63
Query: 664 K 666
K
Sbjct: 64 K 64
Score = 43.6 bits (98), Expect = 9e-04
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = +2
Query: 671 VVNQVECHPYLNXKRLXEFCEAXGVXITXYXPL 769
V NQVECHPY +L +FC+ + IT Y PL
Sbjct: 68 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPL 100
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 45.2 bits (102), Expect = 3e-04
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = +3
Query: 369 LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
+W TF RP+LV+ L+ +L L + Y+DLYL H+P
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFP 35
>U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit
protein.
Length = 367
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 47 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 105
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 106 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 33 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 91
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 92 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 146
>BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 47 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 105
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 106 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 47 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 105
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 106 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein.
Length = 395
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 47 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 105
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 106 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 253
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 47 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 105
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 106 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 254
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 33 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 91
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 92 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 146
>AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 47 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 105
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 106 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 353
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 33 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 91
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 92 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 146
>AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ16180 fis, clone BRHIP3000240, highly similar
to Homo sapiens potassium channel beta 2 subunit
(HKvbeta2.2) mRNA. ).
Length = 415
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 80 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 138
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 139 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 193
>AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta 2
subunit protein.
Length = 353
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 33 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 91
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 92 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 146
>AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta 2
subunit protein.
Length = 367
Score = 36.3 bits (80), Expect = 0.13
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 47 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 105
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ L ++Y+D+ + P
Sbjct: 106 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERLQLEYVDVVFANRP 160
>X83127-1|CAA58208.1| 401|Homo sapiens voltage gated potassium
channels, beta subunit protein.
Length = 401
Score = 35.5 bits (78), Expect = 0.23
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G+++ V + A + G D A VY K + S IK+
Sbjct: 81 LRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKK 139
Query: 330 GVVTREDLFITSKLW--------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
R L IT+KL+ R ++ G L+ +L L ++Y+D+ + P +
Sbjct: 140 KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 196
>U33428-1|AAC50953.1| 401|Homo sapiens K+ channel beta 1a subunit
protein.
Length = 401
Score = 35.5 bits (78), Expect = 0.23
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G+++ V + A + G D A VY K + S IK+
Sbjct: 81 LRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKK 139
Query: 330 GVVTREDLFITSKLW--------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
R L IT+KL+ R ++ G L+ +L L ++Y+D+ + P +
Sbjct: 140 KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 196
>U16953-1|AAC50122.1| 408|Homo sapiens potassium channel beta3
subunit protein.
Length = 408
Score = 35.5 bits (78), Expect = 0.23
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G+++ V + A + G D A VY K + S IK+
Sbjct: 88 LRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKK 146
Query: 330 GVVTREDLFITSKLW--------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
R L IT+KL+ R ++ G L+ +L L ++Y+D+ + P +
Sbjct: 147 KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 203
>L47665-1|AAC41926.1| 419|Homo sapiens K+ channel beta-subunit
protein.
Length = 419
Score = 35.5 bits (78), Expect = 0.23
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G+++ V + A + G D A VY K + S IK+
Sbjct: 99 LRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKK 157
Query: 330 GVVTREDLFITSKLW--------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
R L IT+KL+ R ++ G L+ +L L ++Y+D+ + P +
Sbjct: 158 KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 214
>L39833-1|AAC37573.1| 408|Homo sapiens K+ channel beta-subunit
protein.
Length = 408
Score = 35.5 bits (78), Expect = 0.23
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G+++ V + A + G D A VY K + S IK+
Sbjct: 88 LRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKK 146
Query: 330 GVVTREDLFITSKLW--------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
R L IT+KL+ R ++ G L+ +L L ++Y+D+ + P +
Sbjct: 147 KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 203
>BC043166-1|AAH43166.1| 401|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 1
protein.
Length = 401
Score = 35.5 bits (78), Expect = 0.23
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G+++ V + A + G D A VY K + S IK+
Sbjct: 81 LRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKK 139
Query: 330 GVVTREDLFITSKLW--------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 479
R L IT+KL+ R ++ G L+ +L L ++Y+D+ + P +
Sbjct: 140 KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG-LKGSLQRLQLEYVDVVFANRPDS 196
>CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 33.9 bits (74), Expect = 0.71
Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G++T + + A D G D A VY K + + IK+
Sbjct: 33 LRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGK-AEVVLGNIIKK 91
Query: 330 GVVTREDLFITSKL-W-------NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 473
R L IT+K+ W R ++ G L+ +L+ ++Y+D+ + P
Sbjct: 92 KGWRRSSLVITTKIFWGGKAETERGLSRKHIIEG-LKASLERRQLEYVDVVFANRP 146
>BC043183-1|AAH43183.1| 1284|Homo sapiens collagen, type XX, alpha 1
protein.
Length = 1284
Score = 32.7 bits (71), Expect = 1.6
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Frame = +2
Query: 410 PAGDPGQSERSVLGSVPDTLAPGLARKTALSSRPTNQVKSSSRT---SITWTPXRLWSRS 580
P G+ E SV G++ + PGL R T + +R+ S+ +TP + SRS
Sbjct: 684 PLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTV-SRS 742
Query: 581 SKRVWSRASESPTSTRXXW 637
+ ASE+P S + W
Sbjct: 743 PPSNLALASETPDSLQVSW 761
>AB040943-1|BAA96034.1| 1140|Homo sapiens KIAA1510 protein protein.
Length = 1140
Score = 32.7 bits (71), Expect = 1.6
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Frame = +2
Query: 410 PAGDPGQSERSVLGSVPDTLAPGLARKTALSSRPTNQVKSSSRT---SITWTPXRLWSRS 580
P G+ E SV G++ + PGL R T + +R+ S+ +TP + SRS
Sbjct: 534 PLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTV-SRS 592
Query: 581 SKRVWSRASESPTSTRXXW 637
+ ASE+P S + W
Sbjct: 593 PPSNLALASETPDSLQVSW 611
>AY780786-1|AAV98356.1| 372|Homo sapiens potassium voltage-gated
channel beta subunit protein.
Length = 372
Score = 31.9 bits (69), Expect = 2.9
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Frame = +3
Query: 165 LKCPILGLGTWKSKPGEVTQAVKD-----AIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 329
L+ LGLGTW + G+++ V + A + G D A VY K + S IK+
Sbjct: 81 LRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGK-AEVILGSIIKK 139
Query: 330 GVVTREDLFITSKLW 374
R L IT+KL+
Sbjct: 140 KGWRRSSLVITTKLY 154
>BC111958-1|AAI11959.1| 710|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 3 protein.
Length = 710
Score = 31.1 bits (67), Expect = 5.0
Identities = 22/47 (46%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Frame = -2
Query: 477 PGASVS-GTDPSTERSDCPGSPAGHRAPSPGDETCSTVSKL*TDLPS 340
P +SVS G+ PS+ RS +PAG SPG + ST L DLPS
Sbjct: 547 PTSSVSPGSPPSSPRSR--DAPAGSPPASPGPQGPSTKLPLSLDLPS 591
>BC101756-1|AAI01757.1| 710|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 3 protein.
Length = 710
Score = 31.1 bits (67), Expect = 5.0
Identities = 22/47 (46%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Frame = -2
Query: 477 PGASVS-GTDPSTERSDCPGSPAGHRAPSPGDETCSTVSKL*TDLPS 340
P +SVS G+ PS+ RS +PAG SPG + ST L DLPS
Sbjct: 547 PTSSVSPGSPPSSPRSR--DAPAGSPPASPGPQGPSTKLPLSLDLPS 591
>AK074082-1|BAB84908.1| 497|Homo sapiens FLJ00153 protein protein.
Length = 497
Score = 31.1 bits (67), Expect = 5.0
Identities = 22/47 (46%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Frame = -2
Query: 477 PGASVS-GTDPSTERSDCPGSPAGHRAPSPGDETCSTVSKL*TDLPS 340
P +SVS G+ PS+ RS +PAG SPG + ST L DLPS
Sbjct: 344 PTSSVSPGSPPSSPRSR--DAPAGSPPASPGPQGPSTKLPLSLDLPS 388
>AB038782-1|BAB12116.1| 878|Homo sapiens intestinal mucin protein.
Length = 878
Score = 31.1 bits (67), Expect = 5.0
Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +2
Query: 458 PDTLAPGLARKTALSSRPTNQVKSSSRTSI--TWTPXRLWSRSSKRVWSRASESPTSTRX 631
P + P + R ++ S+ P+ +S T + T TP L SR + R+ S+ + T T
Sbjct: 449 PSSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQMTTQSTLTTT 508
Query: 632 XWRGCCXTRLSSXVVNQVECHPYLNXKR 715
GC + Q C P + R
Sbjct: 509 --AGCTCDNGGTWEQGQCACLPGFSGDR 534
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 30.7 bits (66), Expect = 6.6
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +3
Query: 225 AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV---TREDLFITSKLWNTFH-RP 392
AV+ ++ G+ +D A++Y + + E I + G+ R + + W+ +P
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKP 87
Query: 393 DLVRGALQETLDNLNVQYLDLYLIHWP 473
D VR L+ +L L +DL+ +H P
Sbjct: 88 DSVRSQLETSLKRLQCPQVDLFYLHTP 114
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 30.3 bits (65), Expect = 8.8
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +3
Query: 225 AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV---TREDLFITSKLWNTFH-RP 392
AV+ ++ G+ +D A++Y + + E I + G+ R + + W+ +P
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKP 87
Query: 393 DLVRGALQETLDNLNVQYLDLYLIHWP 473
D VR L+ +L L +DL+ +H P
Sbjct: 88 DSVRSQLETSLKRLQCPQVDLFYLHAP 114
>U72619-1|AAB61992.1| 22|Homo sapiens aldose reductase protein.
Length = 22
Score = 30.3 bits (65), Expect = 8.8
Identities = 12/15 (80%), Positives = 12/15 (80%)
Frame = +3
Query: 156 NNELKCPILGLGTWK 200
NN K PILGLGTWK
Sbjct: 8 NNGAKMPILGLGTWK 22
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 30.3 bits (65), Expect = 8.8
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +3
Query: 225 AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV---TREDLFITSKLWNTFH-RP 392
AV+ ++ G+ +D A++Y + + E I + G+ R + + W+ +P
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKP 87
Query: 393 DLVRGALQETLDNLNVQYLDLYLIHWP 473
D VR L+ +L L +DL+ +H P
Sbjct: 88 DSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 30.3 bits (65), Expect = 8.8
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +3
Query: 225 AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV---TREDLFITSKLWNTFH-RP 392
AV+ ++ G+ +D A++Y + + E I + G+ R + + W+ +P
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKP 87
Query: 393 DLVRGALQETLDNLNVQYLDLYLIHWP 473
D VR L+ +L L +DL+ +H P
Sbjct: 88 DSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 30.3 bits (65), Expect = 8.8
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +3
Query: 225 AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV---TREDLFITSKLWNTFH-RP 392
AV+ ++ G+ +D A++Y + + E I + G+ R + + W+ +P
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKP 87
Query: 393 DLVRGALQETLDNLNVQYLDLYLIHWP 473
D VR L+ +L L +DL+ +H P
Sbjct: 88 DSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 30.3 bits (65), Expect = 8.8
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +3
Query: 225 AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV---TREDLFITSKLWNTFH-RP 392
AV+ ++ G+ +D A++Y + + E I + G+ R + + W+ +P
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKP 87
Query: 393 DLVRGALQETLDNLNVQYLDLYLIHWP 473
D VR L+ +L L +DL+ +H P
Sbjct: 88 DSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 30.3 bits (65), Expect = 8.8
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +3
Query: 225 AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV---TREDLFITSKLWNTFH-RP 392
AV+ ++ G+ +D A++Y + + E I + G+ R + + W+ +P
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKP 87
Query: 393 DLVRGALQETLDNLNVQYLDLYLIHWP 473
D VR L+ +L L +DL+ +H P
Sbjct: 88 DSVRSQLETSLKRLQCPQVDLFYLHAP 114
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 30.3 bits (65), Expect = 8.8
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +3
Query: 225 AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV---TREDLFITSKLWNTFH-RP 392
AV+ ++ G+ +D A++Y + + E I + G+ R + + W+ +P
Sbjct: 58 AVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKP 115
Query: 393 DLVRGALQETLDNLNVQYLDLYLIHWP 473
D VR L+ +L L +DL+ +H P
Sbjct: 116 DSVRSQLETSLKRLQCPQVDLFYLHAP 142
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 30.3 bits (65), Expect = 8.8
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +3
Query: 225 AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV---TREDLFITSKLWNTFH-RP 392
AV+ ++ G+ +D A++Y + + E I + G+ R + + W+ +P
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKP 87
Query: 393 DLVRGALQETLDNLNVQYLDLYLIHWP 473
D VR L+ +L L +DL+ +H P
Sbjct: 88 DSVRSQLETSLKRLQCPQVDLFYLHAP 114
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 30.3 bits (65), Expect = 8.8
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +3
Query: 225 AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV---TREDLFITSKLWNTFH-RP 392
AV+ ++ G+ +D A++Y + + E I + G+ R + + W+ +P
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKP 87
Query: 393 DLVRGALQETLDNLNVQYLDLYLIHWP 473
D VR L+ +L L +DL+ +H P
Sbjct: 88 DSVRSQLETSLKRLQCPQVDLFYLHAP 114
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,071,944
Number of Sequences: 237096
Number of extensions: 2278475
Number of successful extensions: 6718
Number of sequences better than 10.0: 130
Number of HSP's better than 10.0 without gapping: 6043
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6709
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10203625794
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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