Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP03_FL5_H22
(899 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein. 264 2e-70
M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase p... 264 2e-70
BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle... 264 2e-70
BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle... 264 2e-70
BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle... 264 2e-70
BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle... 264 2e-70
AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle... 264 2e-70
AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isofo... 264 3e-70
M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene ... 264 4e-70
BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle... 261 3e-69
M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein. 259 1e-68
U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L isoe... 256 1e-67
U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R isoe... 256 1e-67
D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein. 256 1e-67
BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver ... 256 1e-67
AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver ... 256 1e-67
AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver... 256 1e-67
AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver... 256 1e-67
AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein. 256 1e-67
BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein. 71 4e-12
BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein. 53 1e-06
BX538020-1|CAD97966.1| 1510|Homo sapiens hypothetical protein pr... 30 10.0
AB023164-1|BAA76791.3| 2330|Homo sapiens KIAA0947 protein protein. 30 10.0
>X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein.
Length = 531
Score = 264 bits (648), Expect = 2e-70
Identities = 126/214 (58%), Positives = 164/214 (76%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 359 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 538
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 539 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 718
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 719 KGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
>M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase
protein.
Length = 531
Score = 264 bits (648), Expect = 2e-70
Identities = 126/214 (58%), Positives = 164/214 (76%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 359 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 538
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 539 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 718
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 719 KGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
>BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 264 bits (648), Expect = 2e-70
Identities = 126/214 (58%), Positives = 164/214 (76%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 359 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 538
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 539 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 718
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 719 KGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
>BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 264 bits (648), Expect = 2e-70
Identities = 126/214 (58%), Positives = 164/214 (76%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 359 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 538
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 539 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 718
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 719 KGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
>BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 264 bits (648), Expect = 2e-70
Identities = 126/214 (58%), Positives = 164/214 (76%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 359 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 538
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 539 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 718
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 719 KGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
>BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 264 bits (648), Expect = 2e-70
Identities = 126/214 (58%), Positives = 164/214 (76%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 359 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 538
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 539 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 718
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 719 KGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
>AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 264 bits (648), Expect = 2e-70
Identities = 126/214 (58%), Positives = 164/214 (76%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 359 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 538
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 539 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 718
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 719 KGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
>AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isoform
1 variant protein.
Length = 531
Score = 264 bits (647), Expect = 3e-70
Identities = 126/214 (58%), Positives = 164/214 (76%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 359 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 538
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 539 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 718
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKRKGADFLVTEVENGGSLGSK 206
Query: 719 KGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
>M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene
encoding cytosolic thyroid hormone-binding protein,
complete cds. ).
Length = 531
Score = 264 bits (646), Expect = 4e-70
Identities = 125/214 (58%), Positives = 164/214 (76%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 359 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 538
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AE+ELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPYLYRPVAVALDTKGPEIRTGLIKGSGTAELELKKGATLKITLDN 146
Query: 539 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 718
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG LGS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSK 206
Query: 719 KGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
>BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 261 bits (639), Expect = 3e-69
Identities = 125/214 (58%), Positives = 163/214 (76%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 359 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 538
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 539 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 718
Y EK + + +++DYKNI VV+ G++I++DDGLIS+ + AD L +ENGG L S+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLVSK 206
Query: 719 KGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 207 KGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
>M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein.
Length = 543
Score = 259 bits (634), Expect = 1e-68
Identities = 126/217 (58%), Positives = 163/217 (75%), Gaps = 3/217 (1%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 39 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 98
Query: 359 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 529
TI N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 99 TIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 155
Query: 530 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 709
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q +S + L +ENGG+L
Sbjct: 156 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKISPEGLVTQVENGGVL 215
Query: 710 GSRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
GSRKGVNLPG VDLP +SE+D D FGV GVD++
Sbjct: 216 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIV 252
>U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L
isoenzyme protein.
Length = 566
Score = 256 bits (626), Expect = 1e-67
Identities = 124/217 (57%), Positives = 162/217 (74%), Gaps = 3/217 (1%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 62 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 121
Query: 359 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 529
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 122 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 178
Query: 530 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 709
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 179 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 238
Query: 710 GSRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
GSRKGVNLPG VDLP +SE+D D FGV GVD++
Sbjct: 239 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIV 275
>U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R
isoenzyme protein.
Length = 587
Score = 256 bits (626), Expect = 1e-67
Identities = 124/217 (57%), Positives = 162/217 (74%), Gaps = 3/217 (1%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 83 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 142
Query: 359 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 529
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 143 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 199
Query: 530 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 709
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 200 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 259
Query: 710 GSRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
GSRKGVNLPG VDLP +SE+D D FGV GVD++
Sbjct: 260 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIV 296
>D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein.
Length = 599
Score = 256 bits (626), Expect = 1e-67
Identities = 124/217 (57%), Positives = 162/217 (74%), Gaps = 3/217 (1%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 95 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 154
Query: 359 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 529
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 155 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 211
Query: 530 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 709
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 212 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 271
Query: 710 GSRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
GSRKGVNLPG VDLP +SE+D D FGV GVD++
Sbjct: 272 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIV 308
>BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 256 bits (626), Expect = 1e-67
Identities = 124/217 (57%), Positives = 162/217 (74%), Gaps = 3/217 (1%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 359 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 529
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 530 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 709
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 710 GSRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
GSRKGVNLPG VDLP +SE+D D FGV GVD++
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIV 283
>AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 256 bits (626), Expect = 1e-67
Identities = 124/217 (57%), Positives = 162/217 (74%), Gaps = 3/217 (1%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 359 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 529
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 530 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 709
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 710 GSRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
GSRKGVNLPG VDLP +SE+D D FGV GVD++
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIV 283
>AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 585
Score = 256 bits (626), Expect = 1e-67
Identities = 124/217 (57%), Positives = 162/217 (74%), Gaps = 3/217 (1%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 81 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 140
Query: 359 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 529
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 141 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 197
Query: 530 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 709
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 198 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 257
Query: 710 GSRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
GSRKGVNLPG VDLP +SE+D D FGV GVD++
Sbjct: 258 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIV 294
>AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 565
Score = 256 bits (626), Expect = 1e-67
Identities = 124/217 (57%), Positives = 162/217 (74%), Gaps = 3/217 (1%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 61 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 120
Query: 359 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 529
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 121 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 177
Query: 530 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 709
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 178 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 237
Query: 710 GSRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
GSRKGVNLPG VDLP +SE+D D FGV GVD++
Sbjct: 238 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIV 274
>AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein.
Length = 574
Score = 256 bits (626), Expect = 1e-67
Identities = 124/217 (57%), Positives = 162/217 (74%), Gaps = 3/217 (1%)
Frame = +2
Query: 179 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 358
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 359 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 529
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 530 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 709
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 710 GSRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
GSRKGVNLPG VDLP +SE+D D FGV GVD++
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIV 283
>BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein.
Length = 343
Score = 71.3 bits (167), Expect = 4e-12
Identities = 34/51 (66%), Positives = 37/51 (72%)
Frame = +2
Query: 668 ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
AD L +ENGG LGS+KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 2 ADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 52
>BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein.
Length = 366
Score = 53.2 bits (122), Expect = 1e-06
Identities = 25/36 (69%), Positives = 27/36 (75%)
Frame = +2
Query: 713 SRKGVNLPGIPVDLPAVSEKDKSDXLFGVXXGVDMI 820
S+KGVNLPG VDLPAVSEKD D FGV VDM+
Sbjct: 40 SKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 75
>BX538020-1|CAD97966.1| 1510|Homo sapiens hypothetical protein
protein.
Length = 1510
Score = 30.3 bits (65), Expect = 10.0
Identities = 13/41 (31%), Positives = 22/41 (53%)
Frame = -3
Query: 819 IISTPXXTPKSXSDLSFSETAGRSTGMPGRLTPFRDPSIPP 697
+I+TP T + S L S + G+++PFR+ +PP
Sbjct: 883 LIATPPRTSQPLSPLISSSSPSSPASPVGQVSPFRETPVPP 923
>AB023164-1|BAA76791.3| 2330|Homo sapiens KIAA0947 protein protein.
Length = 2330
Score = 30.3 bits (65), Expect = 10.0
Identities = 13/41 (31%), Positives = 22/41 (53%)
Frame = -3
Query: 819 IISTPXXTPKSXSDLSFSETAGRSTGMPGRLTPFRDPSIPP 697
+I+TP T + S L S + G+++PFR+ +PP
Sbjct: 1703 LIATPPRTSQPLSPLISSSSPSSPASPVGQVSPFRETPVPP 1743
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 120,645,180
Number of Sequences: 237096
Number of extensions: 2441399
Number of successful extensions: 6581
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 6275
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6571
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11603768198
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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