Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP03_FL5_C15
(844 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein. 391 e-108
AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2 prot... 391 e-108
AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1 prot... 388 e-107
AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein. 388 e-107
AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens ... 386 e-107
AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens ... 151 4e-36
U57627-1|AAB03839.2| 901|Homo sapiens ocrl1 protein. 31 6.9
M88162-1|AAA59964.2| 968|Homo sapiens Lowe oculocerebrorenal sy... 31 6.9
BC130612-1|AAI30613.1| 893|Homo sapiens oculocerebrorenal syndr... 31 6.9
BC094726-1|AAH94726.1| 893|Homo sapiens oculocerebrorenal syndr... 31 6.9
AL662877-2|CAI41087.1| 893|Homo sapiens oculocerebrorenal syndr... 31 6.9
AL662877-1|CAI41088.1| 901|Homo sapiens oculocerebrorenal syndr... 31 6.9
AL138745-5|CAI42615.1| 893|Homo sapiens oculocerebrorenal syndr... 31 6.9
AL138745-4|CAI42616.1| 901|Homo sapiens oculocerebrorenal syndr... 31 6.9
AL022162-2|CAI95696.1| 893|Homo sapiens oculocerebrorenal syndr... 31 6.9
AL022162-1|CAI95695.1| 901|Homo sapiens oculocerebrorenal syndr... 31 6.9
>BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein.
Length = 418
Score = 391 bits (962), Expect = e-108
Identities = 191/240 (79%), Positives = 203/240 (84%)
Frame = +3
Query: 123 MEIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 302
M IKFLEVIKPFC++LPEI KPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 303 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKXFG 482
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQK FG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 483 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGXXXXXXXXXXQKGYGLGXGIS 662
M+IT+GQAIVYVMTGMYG+P+E+GAG+CLLIIIQLFVAG QKGYGLG GIS
Sbjct: 121 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS 180
Query: 663 LXXATNICETIVWKAFSPXTVXTGRGHXIRGVL*XHCSICRXNXXDKXRXLREAFYRQXL 842
L ATNICETIVWKAFSP T+ TGRG G + + DK R LREAFYRQ L
Sbjct: 181 LFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLL-ATRTDKVRALREAFYRQNL 239
>AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2
protein.
Length = 476
Score = 391 bits (962), Expect = e-108
Identities = 191/240 (79%), Positives = 203/240 (84%)
Frame = +3
Query: 123 MEIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 302
M IKFLEVIKPFC++LPEI KPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 303 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKXFG 482
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQK FG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 483 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGXXXXXXXXXXQKGYGLGXGIS 662
M+IT+GQAIVYVMTGMYG+P+E+GAG+CLLIIIQLFVAG QKGYGLG GIS
Sbjct: 121 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS 180
Query: 663 LXXATNICETIVWKAFSPXTVXTGRGHXIRGVL*XHCSICRXNXXDKXRXLREAFYRQXL 842
L ATNICETIVWKAFSP T+ TGRG G + + DK R LREAFYRQ L
Sbjct: 181 LFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLL-ATRTDKVRALREAFYRQNL 239
>AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1
protein.
Length = 476
Score = 388 bits (955), Expect = e-107
Identities = 191/240 (79%), Positives = 201/240 (83%)
Frame = +3
Query: 123 MEIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 302
M IKFLEVIKPFC ILPEI KPERKIQF+EKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 303 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKXFG 482
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQK FG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 483 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGXXXXXXXXXXQKGYGLGXGIS 662
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAG QKGYGLG GIS
Sbjct: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS 180
Query: 663 LXXATNICETIVWKAFSPXTVXTGRGHXIRGVL*XHCSICRXNXXDKXRXLREAFYRQXL 842
L ATNICETIVWKAFSP TV TGRG G + + DK R LREAFYRQ L
Sbjct: 181 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLL-ATRTDKVRALREAFYRQNL 239
>AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein.
Length = 476
Score = 388 bits (955), Expect = e-107
Identities = 191/240 (79%), Positives = 201/240 (83%)
Frame = +3
Query: 123 MEIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 302
M IKFLEVIKPFC ILPEI KPERKIQF+EKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 303 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKXFG 482
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQK FG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 483 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGXXXXXXXXXXQKGYGLGXGIS 662
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAG QKGYGLG GIS
Sbjct: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS 180
Query: 663 LXXATNICETIVWKAFSPXTVXTGRGHXIRGVL*XHCSICRXNXXDKXRXLREAFYRQXL 842
L ATNICETIVWKAFSP TV TGRG G + + DK R LREAFYRQ L
Sbjct: 181 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLL-ATRTDKVRALREAFYRQNL 239
>AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens
cDNA FLJ12578 fis, clone NT2RM4001054, moderately
similar to Homo sapiens sec61 homolog mRNA. ).
Length = 437
Score = 386 bits (951), Expect = e-107
Identities = 189/240 (78%), Positives = 202/240 (84%)
Frame = +3
Query: 123 MEIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 302
M IKFLEVIKPFC++ PEI KPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVPPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 303 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKXFG 482
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQK FG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 483 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGXXXXXXXXXXQKGYGLGXGIS 662
M+IT+GQAIVYV+TGMYG+P+E+GAG+CLLIIIQLFVAG QKGYGLG GIS
Sbjct: 121 MIITIGQAIVYVITGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS 180
Query: 663 LXXATNICETIVWKAFSPXTVXTGRGHXIRGVL*XHCSICRXNXXDKXRXLREAFYRQXL 842
L ATNICETIVWKAFSP T+ TGRG G + + DK R LREAFYRQ L
Sbjct: 181 LFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLL-ATRTDKVRALREAFYRQNL 239
>AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens
cDNA FLJ90447 fis, clone NT2RP3001240, highly similar to
Canis familiaris sec61 homologue mRNA. ).
Length = 356
Score = 151 bits (365), Expect = 4e-36
Identities = 76/120 (63%), Positives = 84/120 (70%)
Frame = +3
Query: 483 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGXXXXXXXXXXQKGYGLGXGIS 662
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAG QKGYGLG GIS
Sbjct: 1 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS 60
Query: 663 LXXATNICETIVWKAFSPXTVXTGRGHXIRGVL*XHCSICRXNXXDKXRXLREAFYRQXL 842
L ATNICETIVWKAFSP TV TGRG G + + DK R LREA YRQ L
Sbjct: 61 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLL-ATRTDKVRALREALYRQNL 119
>U57627-1|AAB03839.2| 901|Homo sapiens ocrl1 protein.
Length = 901
Score = 30.7 bits (66), Expect = 6.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +2
Query: 200 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 340
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 775 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 827
>M88162-1|AAA59964.2| 968|Homo sapiens Lowe oculocerebrorenal
syndrome protein protein.
Length = 968
Score = 30.7 bits (66), Expect = 6.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +2
Query: 200 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 340
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 842 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 894
>BC130612-1|AAI30613.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 30.7 bits (66), Expect = 6.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +2
Query: 200 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 340
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 767 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 819
>BC094726-1|AAH94726.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 30.7 bits (66), Expect = 6.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +2
Query: 200 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 340
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 767 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 819
>AL662877-2|CAI41087.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 30.7 bits (66), Expect = 6.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +2
Query: 200 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 340
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 767 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 819
>AL662877-1|CAI41088.1| 901|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 901
Score = 30.7 bits (66), Expect = 6.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +2
Query: 200 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 340
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 775 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 827
>AL138745-5|CAI42615.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 30.7 bits (66), Expect = 6.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +2
Query: 200 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 340
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 767 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 819
>AL138745-4|CAI42616.1| 901|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 901
Score = 30.7 bits (66), Expect = 6.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +2
Query: 200 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 340
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 775 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 827
>AL022162-2|CAI95696.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 30.7 bits (66), Expect = 6.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +2
Query: 200 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 340
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 767 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 819
>AL022162-1|CAI95695.1| 901|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 901
Score = 30.7 bits (66), Expect = 6.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +2
Query: 200 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 340
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 775 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 827
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,201,463
Number of Sequences: 237096
Number of extensions: 2307069
Number of successful extensions: 3977
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3864
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3968
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10649685938
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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