Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP02_FL5_O13
(848 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein. 199 9e-51
M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase p... 199 9e-51
BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle... 199 9e-51
BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle... 199 9e-51
BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle... 199 9e-51
BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle... 199 9e-51
BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle... 199 9e-51
AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle... 199 9e-51
AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isofo... 199 9e-51
M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene ... 198 2e-50
M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein. 190 4e-48
U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L isoe... 189 1e-47
U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R isoe... 189 1e-47
D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein. 189 1e-47
BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver ... 189 1e-47
AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver ... 189 1e-47
AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver... 189 1e-47
AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver... 189 1e-47
AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein. 189 1e-47
BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein. 61 6e-09
BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein. 47 1e-04
>X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein.
Length = 531
Score = 199 bits (486), Expect = 9e-51
Identities = 92/157 (58%), Positives = 126/157 (80%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 340 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 519
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 520 DYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISI 630
Y EK + + +++DYKNI VV+ G++I++DDGLIS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISL 183
Score = 60.9 bits (141), Expect = 6e-09
Identities = 28/37 (75%), Positives = 30/37 (81%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG LGS+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 197 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 233
>M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase
protein.
Length = 531
Score = 199 bits (486), Expect = 9e-51
Identities = 92/157 (58%), Positives = 126/157 (80%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 340 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 519
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 520 DYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISI 630
Y EK + + +++DYKNI VV+ G++I++DDGLIS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISL 183
Score = 60.9 bits (141), Expect = 6e-09
Identities = 28/37 (75%), Positives = 30/37 (81%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG LGS+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 197 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 233
>BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 199 bits (486), Expect = 9e-51
Identities = 92/157 (58%), Positives = 126/157 (80%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 340 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 519
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 520 DYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISI 630
Y EK + + +++DYKNI VV+ G++I++DDGLIS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISL 183
Score = 57.2 bits (132), Expect = 7e-08
Identities = 27/37 (72%), Positives = 29/37 (78%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG L S+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 197 VENGGSLVSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 233
>BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 199 bits (486), Expect = 9e-51
Identities = 92/157 (58%), Positives = 126/157 (80%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 340 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 519
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 520 DYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISI 630
Y EK + + +++DYKNI VV+ G++I++DDGLIS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISL 183
Score = 60.9 bits (141), Expect = 6e-09
Identities = 28/37 (75%), Positives = 30/37 (81%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG LGS+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 197 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 233
>BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 199 bits (486), Expect = 9e-51
Identities = 92/157 (58%), Positives = 126/157 (80%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 340 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 519
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 520 DYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISI 630
Y EK + + +++DYKNI VV+ G++I++DDGLIS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISL 183
Score = 60.9 bits (141), Expect = 6e-09
Identities = 28/37 (75%), Positives = 30/37 (81%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG LGS+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 197 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 233
>BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 199 bits (486), Expect = 9e-51
Identities = 92/157 (58%), Positives = 126/157 (80%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 340 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 519
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 520 DYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISI 630
Y EK + + +++DYKNI VV+ G++I++DDGLIS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISL 183
Score = 60.9 bits (141), Expect = 6e-09
Identities = 28/37 (75%), Positives = 30/37 (81%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG LGS+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 197 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 233
>BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 199 bits (486), Expect = 9e-51
Identities = 92/157 (58%), Positives = 126/157 (80%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 340 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 519
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 520 DYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISI 630
Y EK + + +++DYKNI VV+ G++I++DDGLIS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISL 183
Score = 60.9 bits (141), Expect = 6e-09
Identities = 28/37 (75%), Positives = 30/37 (81%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG LGS+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 197 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 233
>AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 199 bits (486), Expect = 9e-51
Identities = 92/157 (58%), Positives = 126/157 (80%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 340 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 519
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 520 DYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISI 630
Y EK + + +++DYKNI VV+ G++I++DDGLIS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISL 183
Score = 60.9 bits (141), Expect = 6e-09
Identities = 28/37 (75%), Positives = 30/37 (81%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG LGS+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 197 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 233
>AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isoform
1 variant protein.
Length = 531
Score = 199 bits (486), Expect = 9e-51
Identities = 92/157 (58%), Positives = 126/157 (80%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 340 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 519
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AEVELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDN 146
Query: 520 DYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISI 630
Y EK + + +++DYKNI VV+ G++I++DDGLIS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISL 183
Score = 60.9 bits (141), Expect = 6e-09
Identities = 28/37 (75%), Positives = 30/37 (81%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG LGS+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 197 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 233
>M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene
encoding cytosolic thyroid hormone-binding protein,
complete cds. ).
Length = 531
Score = 198 bits (484), Expect = 2e-50
Identities = 91/157 (57%), Positives = 126/157 (80%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+HMC LDIDS R +GIICTIGPASR+V L++M+++GMNVAR+NFSHG+HEYHAE
Sbjct: 27 LEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAE 86
Query: 340 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 519
TI+N R A +S+++ +A+ALDTKGPEIRTGL++G G+AE+ELKKG T+K+T +
Sbjct: 87 TIKNVRTATESFASDPYLYRPVAVALDTKGPEIRTGLIKGSGTAELELKKGATLKITLDN 146
Query: 520 DYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISI 630
Y EK + + +++DYKNI VV+ G++I++DDGLIS+
Sbjct: 147 AYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISL 183
Score = 60.9 bits (141), Expect = 6e-09
Identities = 28/37 (75%), Positives = 30/37 (81%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG LGS+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 197 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 233
>M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein.
Length = 543
Score = 190 bits (464), Expect = 4e-48
Identities = 93/161 (57%), Positives = 122/161 (75%), Gaps = 3/161 (1%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 39 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 98
Query: 340 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 510
TI N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 99 TIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 155
Query: 511 TSSDYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISII 633
++ +GN +T++VDY NI VV G RI+IDDGLIS++
Sbjct: 156 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLV 196
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/51 (58%), Positives = 36/51 (70%), Gaps = 1/51 (1%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGVXXXL-I*FRVXIRK 820
+ENGG+LGSRKGVNLPG VDLP +S +D DL FGV + I F +RK
Sbjct: 209 VENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRK 259
>U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L
isoenzyme protein.
Length = 566
Score = 189 bits (460), Expect = 1e-47
Identities = 92/161 (57%), Positives = 122/161 (75%), Gaps = 3/161 (1%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 62 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 121
Query: 340 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 510
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 122 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 178
Query: 511 TSSDYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISII 633
++ +GN +T++VDY NI VV G RI+IDDGLIS++
Sbjct: 179 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLV 219
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/51 (58%), Positives = 36/51 (70%), Gaps = 1/51 (1%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGVXXXL-I*FRVXIRK 820
+ENGG+LGSRKGVNLPG VDLP +S +D DL FGV + I F +RK
Sbjct: 232 VENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRK 282
>U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R
isoenzyme protein.
Length = 587
Score = 189 bits (460), Expect = 1e-47
Identities = 92/161 (57%), Positives = 122/161 (75%), Gaps = 3/161 (1%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 83 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 142
Query: 340 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 510
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 143 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 199
Query: 511 TSSDYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISII 633
++ +GN +T++VDY NI VV G RI+IDDGLIS++
Sbjct: 200 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLV 240
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/51 (58%), Positives = 36/51 (70%), Gaps = 1/51 (1%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGVXXXL-I*FRVXIRK 820
+ENGG+LGSRKGVNLPG VDLP +S +D DL FGV + I F +RK
Sbjct: 253 VENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRK 303
>D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein.
Length = 599
Score = 189 bits (460), Expect = 1e-47
Identities = 92/161 (57%), Positives = 122/161 (75%), Gaps = 3/161 (1%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 95 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 154
Query: 340 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 510
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 155 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 211
Query: 511 TSSDYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISII 633
++ +GN +T++VDY NI VV G RI+IDDGLIS++
Sbjct: 212 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLV 252
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/51 (58%), Positives = 36/51 (70%), Gaps = 1/51 (1%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGVXXXL-I*FRVXIRK 820
+ENGG+LGSRKGVNLPG VDLP +S +D DL FGV + I F +RK
Sbjct: 265 VENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRK 315
>BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 189 bits (460), Expect = 1e-47
Identities = 92/161 (57%), Positives = 122/161 (75%), Gaps = 3/161 (1%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 340 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 510
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 511 TSSDYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISII 633
++ +GN +T++VDY NI VV G RI+IDDGLIS++
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLV 227
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/51 (58%), Positives = 36/51 (70%), Gaps = 1/51 (1%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGVXXXL-I*FRVXIRK 820
+ENGG+LGSRKGVNLPG VDLP +S +D DL FGV + I F +RK
Sbjct: 240 VENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRK 290
>AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 189 bits (460), Expect = 1e-47
Identities = 92/161 (57%), Positives = 122/161 (75%), Gaps = 3/161 (1%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 340 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 510
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 511 TSSDYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISII 633
++ +GN +T++VDY NI VV G RI+IDDGLIS++
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLV 227
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/51 (58%), Positives = 36/51 (70%), Gaps = 1/51 (1%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGVXXXL-I*FRVXIRK 820
+ENGG+LGSRKGVNLPG VDLP +S +D DL FGV + I F +RK
Sbjct: 240 VENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRK 290
>AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 585
Score = 189 bits (460), Expect = 1e-47
Identities = 92/161 (57%), Positives = 122/161 (75%), Gaps = 3/161 (1%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 81 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 140
Query: 340 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 510
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 141 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 197
Query: 511 TSSDYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISII 633
++ +GN +T++VDY NI VV G RI+IDDGLIS++
Sbjct: 198 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLV 238
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/51 (58%), Positives = 36/51 (70%), Gaps = 1/51 (1%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGVXXXL-I*FRVXIRK 820
+ENGG+LGSRKGVNLPG VDLP +S +D DL FGV + I F +RK
Sbjct: 251 VENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRK 301
>AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 565
Score = 189 bits (460), Expect = 1e-47
Identities = 92/161 (57%), Positives = 122/161 (75%), Gaps = 3/161 (1%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 61 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 120
Query: 340 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 510
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 121 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 177
Query: 511 TSSDYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISII 633
++ +GN +T++VDY NI VV G RI+IDDGLIS++
Sbjct: 178 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLV 218
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/51 (58%), Positives = 36/51 (70%), Gaps = 1/51 (1%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGVXXXL-I*FRVXIRK 820
+ENGG+LGSRKGVNLPG VDLP +S +D DL FGV + I F +RK
Sbjct: 231 VENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRK 281
>AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein.
Length = 574
Score = 189 bits (460), Expect = 1e-47
Identities = 92/161 (57%), Positives = 122/161 (75%), Gaps = 3/161 (1%)
Frame = +1
Query: 160 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 339
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 340 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 510
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 511 TSSDYQEKGNTDTIYVDYKNITNVVKPGNRIFIDDGLISII 633
++ +GN +T++VDY NI VV G RI+IDDGLIS++
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLV 227
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/51 (58%), Positives = 36/51 (70%), Gaps = 1/51 (1%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGVXXXL-I*FRVXIRK 820
+ENGG+LGSRKGVNLPG VDLP +S +D DL FGV + I F +RK
Sbjct: 240 VENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRK 290
>BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein.
Length = 343
Score = 60.9 bits (141), Expect = 6e-09
Identities = 28/37 (75%), Positives = 30/37 (81%)
Frame = +2
Query: 671 IENGGMLGSRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
+ENGG LGS+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 9 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGV 45
>BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein.
Length = 366
Score = 46.8 bits (106), Expect = 1e-04
Identities = 22/29 (75%), Positives = 23/29 (79%)
Frame = +2
Query: 695 SRKGVNLPGIPVDLPAVSXKDKSDLLFGV 781
S+KGVNLPG VDLPAVS KD DL FGV
Sbjct: 40 SKKGVNLPGAAVDLPAVSEKDIQDLKFGV 68
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,214,229
Number of Sequences: 237096
Number of extensions: 2326529
Number of successful extensions: 6167
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 5829
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6157
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10761200974
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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