Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP02_FL5_G17
(855 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 159 9e-39
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 159 9e-39
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 159 9e-39
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 159 9e-39
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 159 9e-39
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 159 9e-39
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 159 9e-39
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 150 7e-36
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 149 1e-35
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 149 1e-35
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 149 1e-35
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 139 1e-32
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 139 1e-32
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 126 1e-28
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 126 1e-28
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 126 1e-28
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 126 1e-28
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 126 1e-28
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 126 1e-28
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 126 1e-28
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 126 1e-28
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 126 1e-28
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 120 5e-27
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 120 5e-27
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 119 1e-26
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 119 1e-26
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 119 1e-26
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 119 1e-26
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 119 1e-26
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 119 1e-26
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 119 1e-26
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 119 2e-26
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 118 4e-26
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 118 4e-26
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 118 4e-26
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 118 4e-26
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 118 4e-26
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 118 4e-26
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 72 2e-12
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 1e-08
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 56 2e-07
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 56 2e-07
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 56 2e-07
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 56 2e-07
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 56 2e-07
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 56 2e-07
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 56 2e-07
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 56 2e-07
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 56 2e-07
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 56 2e-07
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 56 2e-07
AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinog... 54 5e-07
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 53 2e-06
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 44 0.001
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 44 0.001
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 44 0.001
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 44 0.001
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 44 0.001
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 44 0.001
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 44 0.001
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 44 0.001
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 44 0.001
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 44 0.001
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 42 0.003
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 42 0.003
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 42 0.003
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 41 0.005
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 39 0.020
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.027
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 37 0.11
AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protei... 32 2.3
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 7.1
AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein. 31 7.1
BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member ... 25 8.8
AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens ... 25 8.8
BC133035-1|AAI33036.1| 129|Homo sapiens keratin associated prot... 30 9.3
BC130399-1|AAI30400.1| 129|Homo sapiens keratin associated prot... 30 9.3
BC020553-1|AAH20553.1| 320|Homo sapiens pyrroline-5-carboxylate... 30 9.3
BC014868-1|AAH14868.1| 320|Homo sapiens pyrroline-5-carboxylate... 30 9.3
AL117348-6|CAI21802.1| 320|Homo sapiens pyrroline-5-carboxylate... 30 9.3
AL117348-5|CAI21801.1| 214|Homo sapiens pyrroline-5-carboxylate... 30 9.3
AF087859-1|AAP97169.1| 320|Homo sapiens pyrroline 5-carboxylate... 30 9.3
AB126075-1|BAD20202.1| 129|Homo sapiens keratin associated prot... 30 9.3
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 159 bits (387), Expect = 9e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +3
Query: 222 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 368
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTV 632
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 83.8 bits (198), Expect = 7e-16
Identities = 39/73 (53%), Positives = 50/73 (68%), Gaps = 1/73 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGLXXP-VFS 813
G +V RQ F EA +PG+ F+AAKFDGILGMA+ I+ ++V P FDN+ Q L +FS
Sbjct: 171 GVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFS 230
Query: 814 FYLNXDPGAXXGG 852
FYL+ DP A GG
Sbjct: 231 FYLSRDPDAQPGG 243
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 159 bits (387), Expect = 9e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +3
Query: 222 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 368
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTV 632
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 83.8 bits (198), Expect = 7e-16
Identities = 39/73 (53%), Positives = 50/73 (68%), Gaps = 1/73 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGLXXP-VFS 813
G +V RQ F EA +PG+ F+AAKFDGILGMA+ I+ ++V P FDN+ Q L +FS
Sbjct: 171 GVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFS 230
Query: 814 FYLNXDPGAXXGG 852
FYL+ DP A GG
Sbjct: 231 FYLSRDPDAQPGG 243
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 159 bits (387), Expect = 9e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +3
Query: 222 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 368
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTV 632
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 83.8 bits (198), Expect = 7e-16
Identities = 39/73 (53%), Positives = 50/73 (68%), Gaps = 1/73 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGLXXP-VFS 813
G +V RQ F EA +PG+ F+AAKFDGILGMA+ I+ ++V P FDN+ Q L +FS
Sbjct: 171 GVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFS 230
Query: 814 FYLNXDPGAXXGG 852
FYL+ DP A GG
Sbjct: 231 FYLSRDPDAQPGG 243
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 159 bits (387), Expect = 9e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +3
Query: 222 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 368
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTV 632
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 83.8 bits (198), Expect = 7e-16
Identities = 39/73 (53%), Positives = 50/73 (68%), Gaps = 1/73 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGLXXP-VFS 813
G +V RQ F EA +PG+ F+AAKFDGILGMA+ I+ ++V P FDN+ Q L +FS
Sbjct: 171 GVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFS 230
Query: 814 FYLNXDPGAXXGG 852
FYL+ DP A GG
Sbjct: 231 FYLSRDPDAQPGG 243
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 159 bits (387), Expect = 9e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +3
Query: 222 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 368
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTV 632
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 83.8 bits (198), Expect = 7e-16
Identities = 39/73 (53%), Positives = 50/73 (68%), Gaps = 1/73 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGLXXP-VFS 813
G +V RQ F EA +PG+ F+AAKFDGILGMA+ I+ ++V P FDN+ Q L +FS
Sbjct: 171 GVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFS 230
Query: 814 FYLNXDPGAXXGG 852
FYL+ DP A GG
Sbjct: 231 FYLSRDPDAQPGG 243
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 159 bits (387), Expect = 9e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +3
Query: 222 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 368
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTV 632
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 83.8 bits (198), Expect = 7e-16
Identities = 39/73 (53%), Positives = 50/73 (68%), Gaps = 1/73 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGLXXP-VFS 813
G +V RQ F EA +PG+ F+AAKFDGILGMA+ I+ ++V P FDN+ Q L +FS
Sbjct: 171 GVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFS 230
Query: 814 FYLNXDPGAXXGG 852
FYL+ DP A GG
Sbjct: 231 FYLSRDPDAQPGG 243
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 159 bits (387), Expect = 9e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +3
Query: 222 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 368
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTV 632
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
Score = 83.8 bits (198), Expect = 7e-16
Identities = 39/73 (53%), Positives = 50/73 (68%), Gaps = 1/73 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGLXXP-VFS 813
G +V RQ F EA +PG+ F+AAKFDGILGMA+ I+ ++V P FDN+ Q L +FS
Sbjct: 171 GVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFS 230
Query: 814 FYLNXDPGAXXGG 852
FYL+ DP A GG
Sbjct: 231 FYLSRDPDAQPGG 243
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 150 bits (363), Expect = 7e-36
Identities = 70/146 (47%), Positives = 98/146 (67%), Gaps = 5/146 (3%)
Frame = +3
Query: 231 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 395
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 396 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 575
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 576 IQYGSGSLSGFLSTDDVTVGGLKGAA 653
IQYG+G + G LS D +T+GG+KGA+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGAS 164
Score = 65.7 bits (153), Expect = 2e-10
Identities = 33/65 (50%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +1
Query: 661 FAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXDPG 837
F EA+ EP L F A FDGILG+ F ++ + V P D + QG L PVFSFYLN DP
Sbjct: 167 FGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPE 226
Query: 838 AXXGG 852
GG
Sbjct: 227 EPDGG 231
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 149 bits (362), Expect = 1e-35
Identities = 70/146 (47%), Positives = 98/146 (67%), Gaps = 5/146 (3%)
Frame = +3
Query: 231 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 395
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 396 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 575
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 576 IQYGSGSLSGFLSTDDVTVGGLKGAA 653
IQYG+G + G LS D +T+GG+KGA+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGAS 164
Score = 65.7 bits (153), Expect = 2e-10
Identities = 33/65 (50%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +1
Query: 661 FAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXDPG 837
F EA+ EP L F A FDGILG+ F ++ + V P D + QG L PVFSFYLN DP
Sbjct: 167 FGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPE 226
Query: 838 AXXGG 852
GG
Sbjct: 227 EPDGG 231
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 149 bits (362), Expect = 1e-35
Identities = 70/146 (47%), Positives = 98/146 (67%), Gaps = 5/146 (3%)
Frame = +3
Query: 231 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 395
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 396 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 575
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 576 IQYGSGSLSGFLSTDDVTVGGLKGAA 653
IQYG+G + G LS D +T+GG+KGA+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGAS 164
Score = 65.7 bits (153), Expect = 2e-10
Identities = 33/65 (50%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +1
Query: 661 FAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXDPG 837
F EA+ EP L F A FDGILG+ F ++ + V P D + QG L PVFSFYLN DP
Sbjct: 167 FGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPE 226
Query: 838 AXXGG 852
GG
Sbjct: 227 EPDGG 231
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 149 bits (362), Expect = 1e-35
Identities = 70/146 (47%), Positives = 98/146 (67%), Gaps = 5/146 (3%)
Frame = +3
Query: 231 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 395
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 396 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 575
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 576 IQYGSGSLSGFLSTDDVTVGGLKGAA 653
IQYG+G + G LS D +T+GG+KGA+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGAS 164
Score = 65.7 bits (153), Expect = 2e-10
Identities = 33/65 (50%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +1
Query: 661 FAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXDPG 837
F EA+ EP L F A FDGILG+ F ++ + V P D + QG L PVFSFYLN DP
Sbjct: 167 FGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPE 226
Query: 838 AXXGG 852
GG
Sbjct: 227 EPDGG 231
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 139 bits (336), Expect = 1e-32
Identities = 64/139 (46%), Positives = 93/139 (66%), Gaps = 5/139 (3%)
Frame = +3
Query: 252 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 416
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 417 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGS 596
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 141
Query: 597 LSGFLSTDDVTVGGLKGAA 653
+ G LS D +T+GG+KGA+
Sbjct: 142 VDGILSEDKLTIGGIKGAS 160
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/65 (44%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Frame = +1
Query: 661 FAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXDPG 837
F EA+ E L F ++ DGILG+ F ++ + V P D + QG L PVFSFY N DP
Sbjct: 163 FGEALWESSLVFTVSRPDGILGLGFPILSVEGVRPPLDVLVEQGLLDKPVFSFYFNRDPE 222
Query: 838 AXXGG 852
GG
Sbjct: 223 VADGG 227
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 139 bits (336), Expect = 1e-32
Identities = 64/139 (46%), Positives = 93/139 (66%), Gaps = 5/139 (3%)
Frame = +3
Query: 252 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 416
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 417 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGS 596
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 145
Query: 597 LSGFLSTDDVTVGGLKGAA 653
+ G LS D +T+GG+KGA+
Sbjct: 146 VDGILSEDKLTIGGIKGAS 164
Score = 58.0 bits (134), Expect = 4e-08
Identities = 29/65 (44%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Frame = +1
Query: 661 FAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXDPG 837
F EA+ E L F ++ DGILG+ F ++ + V P D + QG L PVFSFY N DP
Sbjct: 167 FGEALWESSLVFTVSRPDGILGLGFPILSVEGVRPPLDVLVEQGLLDKPVFSFYFNRDPE 226
Query: 838 AXXGG 852
GG
Sbjct: 227 VADGG 231
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 126 bits (303), Expect = 1e-28
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +3
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
Score = 60.1 bits (139), Expect = 1e-08
Identities = 30/66 (45%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXD 831
Q F E P L F+ A+FDG++GM F A VTP FDN+ +QG L VFSFY N +
Sbjct: 172 QMFGEVTEMPALPFMLAQFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRN 231
Query: 832 PGAXXG 849
+ G
Sbjct: 232 SQSLGG 237
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 1e-28
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +3
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/60 (50%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXD 831
Q F E P L F+ A+FDG++GM F A VTP FDN+ +QG L VFSFY N D
Sbjct: 172 QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 1e-28
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +3
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/60 (50%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXD 831
Q F E P L F+ A+FDG++GM F A VTP FDN+ +QG L VFSFY N D
Sbjct: 172 QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 126 bits (303), Expect = 1e-28
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +3
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/60 (50%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXD 831
Q F E P L F+ A+FDG++GM F A VTP FDN+ +QG L VFSFY N D
Sbjct: 172 QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 1e-28
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +3
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/60 (50%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXD 831
Q F E P L F+ A+FDG++GM F A VTP FDN+ +QG L VFSFY N D
Sbjct: 172 QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 1e-28
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +3
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/60 (50%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXD 831
Q F E P L F+ A+FDG++GM F A VTP FDN+ +QG L VFSFY N D
Sbjct: 172 QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 126 bits (303), Expect = 1e-28
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +3
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
Score = 60.1 bits (139), Expect = 1e-08
Identities = 30/66 (45%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXD 831
Q F E P L F+ A+FDG++GM F A VTP FDN+ +QG L VFSFY N +
Sbjct: 172 QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRN 231
Query: 832 PGAXXG 849
+ G
Sbjct: 232 SQSLGG 237
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 1e-28
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +3
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/60 (50%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXD 831
Q F E P L F+ A+FDG++GM F A VTP FDN+ +QG L VFSFY N D
Sbjct: 172 QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 1e-28
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +3
Query: 369 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 548
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 549 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/60 (50%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXD 831
Q F E P L F+ A+FDG++GM F A VTP FDN+ +QG L VFSFY N D
Sbjct: 172 QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 120 bits (290), Expect = 5e-27
Identities = 67/155 (43%), Positives = 89/155 (57%), Gaps = 12/155 (7%)
Frame = +3
Query: 213 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 362
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 363 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 536
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 537 KSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
S TY + +I YG+GS++G L D V VGG+
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGI 156
Score = 52.0 bits (119), Expect = 3e-06
Identities = 27/60 (45%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGL-XXPVFSFYLNXD 831
Q F + +EPG A FDGILG+A+ +I+ TP FDN+ QGL +FS YL+ D
Sbjct: 161 QIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSAD 220
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 120 bits (290), Expect = 5e-27
Identities = 67/155 (43%), Positives = 89/155 (57%), Gaps = 12/155 (7%)
Frame = +3
Query: 213 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 362
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 363 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 536
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 537 KSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
S TY + +I YG+GS++G L D V VGG+
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGI 156
Score = 52.0 bits (119), Expect = 3e-06
Identities = 27/60 (45%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGL-XXPVFSFYLNXD 831
Q F + +EPG A FDGILG+A+ +I+ TP FDN+ QGL +FS YL+ D
Sbjct: 161 QIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSAD 220
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 1e-26
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +3
Query: 213 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 362
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 363 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 542
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 543 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
Score = 70.1 bits (164), Expect = 9e-12
Identities = 35/72 (48%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGL-XXPVFS 813
G V Q F E+V+EPG FV A+FDGILG+ + ++A VTP FDNM AQ L P+FS
Sbjct: 157 GLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFS 216
Query: 814 FYLNXDPGAXXG 849
Y++ +P G
Sbjct: 217 VYMSSNPEGGAG 228
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 119 bits (287), Expect = 1e-26
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +3
Query: 213 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 362
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 363 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 542
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 543 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
Score = 70.1 bits (164), Expect = 9e-12
Identities = 35/72 (48%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGL-XXPVFS 813
G V Q F E+V+EPG FV A+FDGILG+ + ++A VTP FDNM AQ L P+FS
Sbjct: 157 GLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFS 216
Query: 814 FYLNXDPGAXXG 849
Y++ +P G
Sbjct: 217 VYMSSNPEGGAG 228
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 119 bits (287), Expect = 1e-26
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +3
Query: 213 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 362
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 363 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 542
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 543 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
Score = 70.1 bits (164), Expect = 9e-12
Identities = 35/72 (48%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGL-XXPVFS 813
G V Q F E+V+EPG FV A+FDGILG+ + ++A VTP FDNM AQ L P+FS
Sbjct: 157 GLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFS 216
Query: 814 FYLNXDPGAXXG 849
Y++ +P G
Sbjct: 217 VYMSSNPEGGAG 228
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 1e-26
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +3
Query: 213 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 362
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 363 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 542
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 543 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
Score = 70.1 bits (164), Expect = 9e-12
Identities = 35/72 (48%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGL-XXPVFS 813
G V Q F E+V+EPG FV A+FDGILG+ + ++A VTP FDNM AQ L P+FS
Sbjct: 157 GLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFS 216
Query: 814 FYLNXDPGAXXG 849
Y++ +P G
Sbjct: 217 VYMSSNPEGGAG 228
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 1e-26
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +3
Query: 213 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 362
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 363 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 542
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 543 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
Score = 70.1 bits (164), Expect = 9e-12
Identities = 35/72 (48%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGL-XXPVFS 813
G V Q F E+V+EPG FV A+FDGILG+ + ++A VTP FDNM AQ L P+FS
Sbjct: 157 GLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFS 216
Query: 814 FYLNXDPGAXXG 849
Y++ +P G
Sbjct: 217 VYMSSNPEGGAG 228
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 1e-26
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +3
Query: 213 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 362
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 363 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 542
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 543 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
Score = 70.1 bits (164), Expect = 9e-12
Identities = 35/72 (48%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGL-XXPVFS 813
G V Q F E+V+EPG FV A+FDGILG+ + ++A VTP FDNM AQ L P+FS
Sbjct: 157 GLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFS 216
Query: 814 FYLNXDPGAXXG 849
Y++ +P G
Sbjct: 217 VYMSSNPEGGAG 228
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 119 bits (287), Expect = 1e-26
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +3
Query: 213 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 362
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 363 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 542
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 543 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
Score = 70.1 bits (164), Expect = 9e-12
Identities = 35/72 (48%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +1
Query: 637 GSRVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGL-XXPVFS 813
G V Q F E+V+EPG FV A+FDGILG+ + ++A VTP FDNM AQ L P+FS
Sbjct: 157 GLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFS 216
Query: 814 FYLNXDPGAXXG 849
Y++ +P G
Sbjct: 217 VYMSSNPEGGAG 228
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 119 bits (286), Expect = 2e-26
Identities = 66/155 (42%), Positives = 89/155 (57%), Gaps = 12/155 (7%)
Frame = +3
Query: 213 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 362
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 363 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 536
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 537 KSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 641
S TY + +I YG+GS++G L D V VGG+
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGI 156
Score = 52.0 bits (119), Expect = 3e-06
Identities = 27/60 (45%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQGL-XXPVFSFYLNXD 831
Q F + +EPG A FDGILG+A+ +I+ TP FDN+ QGL +FS YL+ D
Sbjct: 161 QIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSAD 220
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 118 bits (283), Expect = 4e-26
Identities = 65/141 (46%), Positives = 88/141 (62%), Gaps = 9/141 (6%)
Frame = +3
Query: 249 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 401
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 402 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 581
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 582 YGSGSLSGFLSTDDVTVGGLK 644
YGSGSL+GF D +TV ++
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQ 154
Score = 56.4 bits (130), Expect = 1e-07
Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Frame = +1
Query: 643 RVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFY 819
+V Q F + +EPG FV A+FDGI+G+A+ ++ D T M +G L PVFS Y
Sbjct: 154 QVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVY 213
Query: 820 LNXDPGAXXG 849
L+ G+ G
Sbjct: 214 LSNQQGSSGG 223
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 118 bits (283), Expect = 4e-26
Identities = 65/141 (46%), Positives = 88/141 (62%), Gaps = 9/141 (6%)
Frame = +3
Query: 249 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 401
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 402 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 581
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 582 YGSGSLSGFLSTDDVTVGGLK 644
YGSGSL+GF D +TV ++
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQ 154
Score = 56.4 bits (130), Expect = 1e-07
Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Frame = +1
Query: 643 RVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFY 819
+V Q F + +EPG FV A+FDGI+G+A+ ++ D T M +G L PVFS Y
Sbjct: 154 QVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVY 213
Query: 820 LNXDPGAXXG 849
L+ G+ G
Sbjct: 214 LSNQQGSSGG 223
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 118 bits (283), Expect = 4e-26
Identities = 65/141 (46%), Positives = 88/141 (62%), Gaps = 9/141 (6%)
Frame = +3
Query: 249 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 401
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 402 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 581
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 130
Query: 582 YGSGSLSGFLSTDDVTVGGLK 644
YGSGSL+GF D +TV ++
Sbjct: 131 YGSGSLTGFFGYDTLTVQSIQ 151
Score = 56.4 bits (130), Expect = 1e-07
Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Frame = +1
Query: 643 RVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFY 819
+V Q F + +EPG FV A+FDGI+G+A+ ++ D T M +G L PVFS Y
Sbjct: 151 QVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVY 210
Query: 820 LNXDPGAXXG 849
L+ G+ G
Sbjct: 211 LSNQQGSSGG 220
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 118 bits (283), Expect = 4e-26
Identities = 65/141 (46%), Positives = 88/141 (62%), Gaps = 9/141 (6%)
Frame = +3
Query: 249 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 401
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 402 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 581
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 582 YGSGSLSGFLSTDDVTVGGLK 644
YGSGSL+GF D +TV ++
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQ 154
Score = 56.4 bits (130), Expect = 1e-07
Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Frame = +1
Query: 643 RVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFY 819
+V Q F + +EPG FV A+FDGI+G+A+ ++ D T M +G L PVFS Y
Sbjct: 154 QVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVY 213
Query: 820 LNXDPGAXXG 849
L+ G+ G
Sbjct: 214 LSNQQGSSGG 223
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 118 bits (283), Expect = 4e-26
Identities = 65/141 (46%), Positives = 88/141 (62%), Gaps = 9/141 (6%)
Frame = +3
Query: 249 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 401
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 402 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 581
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 582 YGSGSLSGFLSTDDVTVGGLK 644
YGSGSL+GF D +TV ++
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQ 154
Score = 56.4 bits (130), Expect = 1e-07
Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Frame = +1
Query: 643 RVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFY 819
+V Q F + +EPG FV A+FDGI+G+A+ ++ D T M +G L PVFS Y
Sbjct: 154 QVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVY 213
Query: 820 LNXDPGAXXG 849
L+ G+ G
Sbjct: 214 LSNQQGSSGG 223
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 118 bits (283), Expect = 4e-26
Identities = 65/141 (46%), Positives = 88/141 (62%), Gaps = 9/141 (6%)
Frame = +3
Query: 249 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 401
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 402 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 581
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 582 YGSGSLSGFLSTDDVTVGGLK 644
YGSGSL+GF D +TV ++
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQ 154
Score = 56.4 bits (130), Expect = 1e-07
Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Frame = +1
Query: 643 RVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFY 819
+V Q F + +EPG FV A+FDGI+G+A+ ++ D T M +G L PVFS Y
Sbjct: 154 QVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVY 213
Query: 820 LNXDPGAXXG 849
L+ G+ G
Sbjct: 214 LSNQQGSSGG 223
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 72.1 bits (169), Expect = 2e-12
Identities = 29/61 (47%), Positives = 42/61 (68%)
Frame = +3
Query: 459 SNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 638
SN+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 60
Query: 639 L 641
+
Sbjct: 61 I 61
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/60 (50%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
Frame = +1
Query: 655 QTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFYLNXD 831
Q F E P L F+ A+FDG++GM F A VTP FDN+ +QG L VFSFY N D
Sbjct: 65 QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 124
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +3
Query: 249 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 401
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 402 VISIGTPPQSFKVVFDTGSSNL 467
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 66
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 67 TVKYTQGSWTGFVGEDLVTI 86
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 140
Score = 54.4 bits (125), Expect = 5e-07
Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Frame = +1
Query: 643 RVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTIAXDHVTPXFDNMXAQG-LXXPVFSFY 819
+V Q F + +EPG FV A+FDGI+G+A+ ++ D T M +G L PVFS Y
Sbjct: 75 QVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVY 134
Query: 820 LNXDPG 837
L+ G
Sbjct: 135 LSNQQG 140
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 52.8 bits (121), Expect = 2e-06
Identities = 27/74 (36%), Positives = 40/74 (54%)
Frame = +3
Query: 411 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGS 590
IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G ++Y
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQ 56
Query: 591 GSLSGFLSTDDVTV 632
GS +GF+ D VT+
Sbjct: 57 GSWTGFVGEDLVTI 70
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 115
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 116 YVPYTQGKWEGELGTDLVSI 135
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 159
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 160 YVPYTQGKWEGELGTDLVSI 179
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 41.9 bits (94), Expect = 0.003
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTD 620
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 41.9 bits (94), Expect = 0.003
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTD 620
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 41.9 bits (94), Expect = 0.003
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTD 620
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/80 (31%), Positives = 38/80 (47%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 572
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLFSTYRDLRKGV 128
Query: 573 AIQYGSGSLSGFLSTDDVTV 632
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 39.1 bits (87), Expect = 0.020
Identities = 21/66 (31%), Positives = 34/66 (51%)
Frame = +3
Query: 435 KVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLS 614
+++ DTGSSN V Y + +D+ +S TY + G ++Y GS +GF+
Sbjct: 3 QILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVG 56
Query: 615 TDDVTV 632
D VT+
Sbjct: 57 EDLVTI 62
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.027
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +3
Query: 240 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 392
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 393 YYGVISIGTP 422
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 36.7 bits (81), Expect = 0.11
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +3
Query: 393 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 551
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protein
LIP8 protein.
Length = 119
Score = 32.3 bits (70), Expect = 2.3
Identities = 13/33 (39%), Positives = 16/33 (48%)
Frame = -1
Query: 615 WRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTCC 517
W GS+R C + V + S SW CR CC
Sbjct: 8 WPGSKRECANCRVGTSSWRSSGWSWWKDCRPCC 40
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 7.1
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -2
Query: 458 GSGVEYHLERLRRRADTDHSVVLSIK 381
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein.
Length = 559
Score = 30.7 bits (66), Expect = 7.1
Identities = 27/98 (27%), Positives = 34/98 (34%), Gaps = 7/98 (7%)
Frame = -1
Query: 732 GHPEDPVELGGHEGKPGLRHGLGERLXXXXXXXXXXXHQWRGSRRGCRSRTVS--RTGCH 559
G P V +GG G G+ G R R+GC+ R S R G
Sbjct: 398 GFPGFGVGVGGIPGVAGVPGVGGSRSRRCPGSWHFPRSSGSSCRQGCQVRVSSWCRRGSW 457
Query: 558 SRRTSWT-CGCRTCCAA----NKRCWCSGTFWKAPRGW 460
S R SW CG + + WC W+ R W
Sbjct: 458 SWRGSWCRCGSWSWLGSWSWRGSWSWCGSWRWRGSRHW 495
>BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member 12
protein.
Length = 578
Score = 25.4 bits (53), Expect(2) = 8.8
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -1
Query: 384 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 232
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 8.8
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -1
Query: 531 CRTCCAANKRCWCSGTFWKAPRGWRIR 451
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens
cDNA FLJ10260 fis, clone HEMBB1000973, moderately
similar to Mus musculus schlafen3 mRNA. ).
Length = 578
Score = 25.4 bits (53), Expect(2) = 8.8
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -1
Query: 384 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 232
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINASLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 8.8
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -1
Query: 531 CRTCCAANKRCWCSGTFWKAPRGWRIR 451
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>BC133035-1|AAI33036.1| 129|Homo sapiens keratin associated protein
5-6 protein.
Length = 129
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -1
Query: 609 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 490
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>BC130399-1|AAI30400.1| 129|Homo sapiens keratin associated protein
5-6 protein.
Length = 129
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -1
Query: 609 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 490
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>BC020553-1|AAH20553.1| 320|Homo sapiens pyrroline-5-carboxylate
reductase family, member 2 protein.
Length = 320
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +3
Query: 585 GSGSLSGFLSTDDVTVGGLKGAAPDVRRGRVGARACLRGRQVRRDPRDGLXHYRXGPCDP 764
GSG F++ D + GG+K P ++GA+A L ++ D + C P
Sbjct: 175 GSGPAYAFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSP 234
Query: 765 G 767
G
Sbjct: 235 G 235
>BC014868-1|AAH14868.1| 320|Homo sapiens pyrroline-5-carboxylate
reductase family, member 2 protein.
Length = 320
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +3
Query: 585 GSGSLSGFLSTDDVTVGGLKGAAPDVRRGRVGARACLRGRQVRRDPRDGLXHYRXGPCDP 764
GSG F++ D + GG+K P ++GA+A L ++ D + C P
Sbjct: 175 GSGPAYAFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSP 234
Query: 765 G 767
G
Sbjct: 235 G 235
>AL117348-6|CAI21802.1| 320|Homo sapiens pyrroline-5-carboxylate
reductase family, member 2 protein.
Length = 320
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +3
Query: 585 GSGSLSGFLSTDDVTVGGLKGAAPDVRRGRVGARACLRGRQVRRDPRDGLXHYRXGPCDP 764
GSG F++ D + GG+K P ++GA+A L ++ D + C P
Sbjct: 175 GSGPAYAFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSP 234
Query: 765 G 767
G
Sbjct: 235 G 235
>AL117348-5|CAI21801.1| 214|Homo sapiens pyrroline-5-carboxylate
reductase family, member 2 protein.
Length = 214
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +3
Query: 585 GSGSLSGFLSTDDVTVGGLKGAAPDVRRGRVGARACLRGRQVRRDPRDGLXHYRXGPCDP 764
GSG F++ D + GG+K P ++GA+A L ++ D + C P
Sbjct: 128 GSGPAYAFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSP 187
Query: 765 G 767
G
Sbjct: 188 G 188
>AF087859-1|AAP97169.1| 320|Homo sapiens pyrroline 5-carboxylate
reductase protein.
Length = 320
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/61 (27%), Positives = 27/61 (44%)
Frame = +3
Query: 585 GSGSLSGFLSTDDVTVGGLKGAAPDVRRGRVGARACLRGRQVRRDPRDGLXHYRXGPCDP 764
GSG F++ D + GG+K P ++GA+A L ++ D + C P
Sbjct: 175 GSGPAYAFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSP 234
Query: 765 G 767
G
Sbjct: 235 G 235
>AB126075-1|BAD20202.1| 129|Homo sapiens keratin associated protein
protein.
Length = 129
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -1
Query: 609 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 490
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 118,802,759
Number of Sequences: 237096
Number of extensions: 2480391
Number of successful extensions: 5834
Number of sequences better than 10.0: 83
Number of HSP's better than 10.0 without gapping: 5365
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5776
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10872716010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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