Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP01_T7_O13
(783 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. 86 2e-16
AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. 86 2e-16
BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. 71 4e-12
AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens ... 71 4e-12
AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. 71 4e-12
AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 pro... 71 4e-12
AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. 71 4e-12
D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. 70 8e-12
BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. 70 8e-12
X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. 67 6e-11
M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protei... 67 6e-11
BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, ... 67 6e-11
BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin ... 67 6e-11
BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin ... 67 6e-11
AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, ... 67 6e-11
AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, ... 67 6e-11
X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 67 8e-11
BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. 67 8e-11
AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 67 8e-11
AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. 67 8e-11
AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, ... 66 1e-10
AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens ... 65 2e-10
BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. 59 2e-08
BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (am... 50 7e-06
AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis, ... 50 7e-06
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 49 2e-05
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 49 2e-05
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 49 2e-05
AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, ... 46 2e-04
AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, ... 46 2e-04
AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein. 45 3e-04
AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein. 45 3e-04
AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. 45 3e-04
AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. 45 3e-04
AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. 45 3e-04
AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. 45 3e-04
AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. 45 3e-04
AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens ... 44 8e-04
AB209574-1|BAD92811.1| 326|Homo sapiens villin-like variant pro... 40 0.008
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 35 0.38
DQ012935-1|AAY22174.1| 1503|Homo sapiens transient receptor pote... 31 3.5
BC112342-1|AAI12343.1| 1553|Homo sapiens TRPM2 protein protein. 31 3.5
AY603182-1|AAT12288.1| 846|Homo sapiens TRPM2-S protein. 31 3.5
AP001754-4|BAA95563.1| 1503|Homo sapiens transient receptor pote... 31 3.5
AJ878416-1|CAI47593.1| 1503|Homo sapiens transient receptor pote... 31 3.5
AJ417076-1|CAD01139.1| 1449|Homo sapiens putative TRP cation cha... 31 3.5
AB166746-1|BAD83706.1| 1289|Homo sapiens transient receptor pote... 31 3.5
AB166745-1|BAD83705.1| 1503|Homo sapiens transient receptor pote... 31 3.5
AB001535-1|BAA34700.1| 1503|Homo sapiens KNP3 protein. 31 3.5
BC129991-1|AAI29992.1| 754|Homo sapiens PERQ1 protein protein. 30 8.2
>BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein.
Length = 812
Score = 85.8 bits (203), Expect = 2e-16
Identities = 55/158 (34%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 603 DQDHHGRGRVDIV--DKYSSDVDVQKFFT-ALG--SGVKDLVPDESTGGDDQEFERNEAS 439
D++ GR + ++ DK ++ ++ K LG S +K VPDE ++ + S
Sbjct: 189 DRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEI-------IDQKQKS 241
Query: 438 NVILSEVSDATGKIKVTPLS-KPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQA 262
++L +SD+ G++ VT ++ +P Q+ L+ + YILD IYVW GK AT EK A
Sbjct: 242 TIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAA 301
Query: 261 MTKAQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 148
M+KA + K+YPS V V E A FKQ F W
Sbjct: 302 MSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKW 339
Score = 54.8 bits (126), Expect = 3e-07
Identities = 33/98 (33%), Positives = 52/98 (53%), Gaps = 4/98 (4%)
Frame = -1
Query: 429 LSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKA 250
L E S+ TG+ VT ++ F Q++L+P + +LDT +++WIG +A A EK A+ A
Sbjct: 611 LFECSNKTGQFVVTEITD-FTQDDLNPTDVMLLDTWD-QVFLWIGAEANATEKESALATA 668
Query: 249 QELLGAKNYPSW----VQVTRVLQNTEPAAFKQYFFTW 148
Q+ L +PS + + Q EP F +F W
Sbjct: 669 QQYL--HTHPSGRDPDTPILIIKQGFEPPIFTGWFLAW 704
Score = 41.5 bits (93), Expect = 0.003
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ KGKR + +V+ S +GDVF+LD I + G ++ + E+LKA+ A +R
Sbjct: 129 LLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIR 188
Query: 602 IR 597
R
Sbjct: 189 DR 190
>AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein.
Length = 819
Score = 85.8 bits (203), Expect = 2e-16
Identities = 55/158 (34%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 603 DQDHHGRGRVDIV--DKYSSDVDVQKFFT-ALG--SGVKDLVPDESTGGDDQEFERNEAS 439
D++ GR + ++ DK ++ ++ K LG S +K VPDE ++ + S
Sbjct: 196 DRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEI-------IDQKQKS 248
Query: 438 NVILSEVSDATGKIKVTPLS-KPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQA 262
++L +SD+ G++ VT ++ +P Q+ L+ + YILD IYVW GK AT EK A
Sbjct: 249 TIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAA 308
Query: 261 MTKAQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 148
M+KA + K+YPS V V E A FKQ F W
Sbjct: 309 MSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKW 346
Score = 54.8 bits (126), Expect = 3e-07
Identities = 33/98 (33%), Positives = 52/98 (53%), Gaps = 4/98 (4%)
Frame = -1
Query: 429 LSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKA 250
L E S+ TG+ VT ++ F Q++L+P + +LDT +++WIG +A A EK A+ A
Sbjct: 618 LFECSNKTGQFVVTEITD-FTQDDLNPTDVMLLDTWD-QVFLWIGAEANATEKESALATA 675
Query: 249 QELLGAKNYPSW----VQVTRVLQNTEPAAFKQYFFTW 148
Q+ L +PS + + Q EP F +F W
Sbjct: 676 QQYL--HTHPSGRDPDTPILIIKQGFEPPIFTGWFLAW 711
Score = 41.5 bits (93), Expect = 0.003
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ KGKR + +V+ S +GDVF+LD I + G ++ + E+LKA+ A +R
Sbjct: 136 LLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIR 195
Query: 602 IR 597
R
Sbjct: 196 DR 197
>BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein.
Length = 715
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 5/157 (3%)
Frame = -1
Query: 597 DHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVI--LS 424
+ GR + +V++ S ++ K G K +PD GGDD + + ++ + L
Sbjct: 201 ERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDDIIADISNRKMAKLY 252
Query: 423 EVSDATGKIKVTPLSK--PFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTK 253
VSDA+G ++VT +++ PF L + +ILD + I+VW GK A E+ AM
Sbjct: 253 MVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKT 312
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 313 AEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 349
Score = 43.6 bits (98), Expect = 8e-04
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++ A+ L
Sbjct: 620 SNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLKSAKMYL 678
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 148
+ + Q EP F +F W
Sbjct: 679 ETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/60 (33%), Positives = 29/60 (48%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ KG+R V +V S KGD F++D +IY + G E+LKA A +R
Sbjct: 139 LLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIR 198
>AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens
cDNA FLJ90642 fis, clone PLACE1004078, highly similar to
Bovine mRNA for adseverin. ).
Length = 715
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 5/157 (3%)
Frame = -1
Query: 597 DHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVI--LS 424
+ GR + +V++ S ++ K G K +PD GGDD + + ++ + L
Sbjct: 201 ERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDDIIADISNRKMAKLY 252
Query: 423 EVSDATGKIKVTPLSK--PFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTK 253
VSDA+G ++VT +++ PF L + +ILD + I+VW GK A E+ AM
Sbjct: 253 MVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKT 312
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 313 AEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 349
Score = 43.6 bits (98), Expect = 8e-04
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++ A+ L
Sbjct: 620 SNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLKSAKMYL 678
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 148
+ + Q EP F +F W
Sbjct: 679 ETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/60 (33%), Positives = 29/60 (48%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ KG+R V +V S KGD F++D +IY + G E+LKA A +R
Sbjct: 139 LLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIR 198
>AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein.
Length = 715
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 5/157 (3%)
Frame = -1
Query: 597 DHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVI--LS 424
+ GR + +V++ S ++ K G K +PD GGDD + + ++ + L
Sbjct: 201 ERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDDIIADISNRKMAKLY 252
Query: 423 EVSDATGKIKVTPLSK--PFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTK 253
VSDA+G ++VT +++ PF L + +ILD + I+VW GK A E+ AM
Sbjct: 253 MVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKT 312
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 313 AEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 349
Score = 43.6 bits (98), Expect = 8e-04
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++ A+ L
Sbjct: 620 SNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLKSAKMYL 678
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 148
+ + Q EP F +F W
Sbjct: 679 ETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/60 (33%), Positives = 29/60 (48%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ KG+R V +V S KGD F++D +IY + G E+LKA A +R
Sbjct: 139 LLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIR 198
>AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1
protein.
Length = 527
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 5/157 (3%)
Frame = -1
Query: 597 DHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVI--LS 424
+ GR + +V++ S ++ K G K +PD GGDD + + ++ + L
Sbjct: 201 ERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDDIIADISNRKMAKLY 252
Query: 423 EVSDATGKIKVTPLSK--PFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTK 253
VSDA+G ++VT +++ PF L + +ILD + I+VW GK A E+ AM
Sbjct: 253 MVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKT 312
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 313 AEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 349
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/60 (33%), Positives = 29/60 (48%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ KG+R V +V S KGD F++D +IY + G E+LKA A +R
Sbjct: 139 LLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIR 198
>AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein.
Length = 626
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 5/157 (3%)
Frame = -1
Query: 597 DHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVI--LS 424
+ GR + +V++ S ++ K G K +PD GGDD + + ++ + L
Sbjct: 247 ERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDDIIADISNRKMAKLY 298
Query: 423 EVSDATGKIKVTPLSK--PFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTK 253
VSDA+G ++VT +++ PF L + +ILD + I+VW GK A E+ AM
Sbjct: 299 MVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKT 358
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 359 AEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 395
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/60 (33%), Positives = 29/60 (48%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ KG+R V +V S KGD F++D +IY + G E+LKA A +R
Sbjct: 185 LLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIR 244
>D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein.
Length = 686
Score = 70.1 bits (164), Expect = 8e-12
Identities = 46/151 (30%), Positives = 73/151 (48%), Gaps = 2/151 (1%)
Frame = -1
Query: 588 GRGRVDIVDKYSSDVDVQKFFTA-LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSD 412
GR ++ +VD + D+ + A LG V L ++ + + +NV L V +
Sbjct: 33 GRAQIGVVDDEAKAPDLMQIMEAVLGCRVGSL----RAATPSKDINQLQKANVRLYHVYE 88
Query: 411 ATGKIKVTPLSKP-FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLG 235
+ V L+ P Q+ L ++ YILD IYVW G+ ++ E+ A ++A +
Sbjct: 89 KGKDLVVLELATPPLTQDLLQEEDFYILDQGGFKIYVWQGRMSSLQERKAAFSRAVGFIQ 148
Query: 234 AKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
AK YP++ V V E AAFKQ F TW +
Sbjct: 149 AKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 179
Score = 40.3 bits (90), Expect = 0.008
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Frame = -1
Query: 372 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNYPSW----VQV 205
F QE+L + +LDT I++W+G+ A+E +A+ QE L K +P+ +
Sbjct: 462 FSQEDLDKYDIMLLDTWQ-EIFLWLGE--AASEWKEAVAWGQEYL--KTHPAGRSPATPI 516
Query: 204 TRVLQNTEPAAFKQYFFTW 148
V Q EP F +FFTW
Sbjct: 517 VLVKQGHEPPTFIGWFFTW 535
>BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein.
Length = 686
Score = 70.1 bits (164), Expect = 8e-12
Identities = 46/151 (30%), Positives = 73/151 (48%), Gaps = 2/151 (1%)
Frame = -1
Query: 588 GRGRVDIVDKYSSDVDVQKFFTA-LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSD 412
GR ++ +VD + D+ + A LG V L ++ + + +NV L V +
Sbjct: 33 GRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSL----RAATPSKDINQLQKANVRLYHVYE 88
Query: 411 ATGKIKVTPLSKP-FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLG 235
+ V L+ P Q+ L ++ YILD IYVW G+ ++ E+ A ++A +
Sbjct: 89 KGKDLVVLELATPPLTQDLLQEEDFYILDQGGFKIYVWQGRMSSLQERKAAFSRAVGFIQ 148
Query: 234 AKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
AK YP++ V V E AAFKQ F TW +
Sbjct: 149 AKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 179
Score = 40.3 bits (90), Expect = 0.008
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Frame = -1
Query: 372 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNYPSW----VQV 205
F QE+L + +LDT I++W+G+ A+E +A+ QE L K +P+ +
Sbjct: 462 FSQEDLDKYDIMLLDTWQ-EIFLWLGE--AASEWKEAVAWGQEYL--KTHPAGRSPATPI 516
Query: 204 TRVLQNTEPAAFKQYFFTW 148
V Q EP F +FFTW
Sbjct: 517 VLVKQGHEPPTFIGWFFTW 535
>X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein.
Length = 782
Score = 67.3 bits (157), Expect = 6e-11
Identities = 54/188 (28%), Positives = 85/188 (45%), Gaps = 5/188 (2%)
Frame = -1
Query: 621 VRQSSTDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEA 442
V + D + GR RV + ++ + + LG E T +D R A
Sbjct: 243 VSKGIRDNERSGRARVHVSEE---GTEPEAMLQVLGPKPALPAGTEDTAKEDAA-NRKLA 298
Query: 441 SNVILSEVSDATGKIKVTPLS--KPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEK 271
L +VS+ G + V+ ++ PF Q L ++ +ILD G I+VW GKQA E+
Sbjct: 299 K---LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEER 355
Query: 270 SQAMTKAQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQ-- 97
A+ A + + +YP QV+ + + E FKQ+F WRD + + L +
Sbjct: 356 KAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIA 415
Query: 96 NKEKVP*D 73
N E+VP D
Sbjct: 416 NVERVPFD 423
Score = 50.4 bits (115), Expect = 7e-06
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ G+ + + QE+L+ + +LDT ++VW+GK + EK++A+T A+ +
Sbjct: 673 SNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKTEALTSAKRYI 731
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
N +T V Q EP +F +F W D
Sbjct: 732 ETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+FQ KG+R V +V S GD F+LD N+I+ + G + E+LKA + +R
Sbjct: 189 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 248
>M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protein
protein.
Length = 348
Score = 67.3 bits (157), Expect = 6e-11
Identities = 44/156 (28%), Positives = 74/156 (47%), Gaps = 3/156 (1%)
Frame = -1
Query: 603 DQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVILS 424
D + G+ +V+IV ++ + G K + E +D ++ A L
Sbjct: 199 DSERQGKAQVEIVTDGEEPAEMIQVL-----GPKPALK-EGNPEEDLTADKANAQAAALY 252
Query: 423 EVSDATGKIKVTPL--SKPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTK 253
+VSDATG++ +T + S PF E L + ++LD + G IY+W G++A E+ A+
Sbjct: 253 KVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQV 312
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWR 145
A+ + Y QV + Q E FKQ+F W+
Sbjct: 313 AEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDWK 348
Score = 37.9 bits (84), Expect = 0.041
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
++Q KGK+ + + S GD F+LD +I+ + G K+ +E+ KA A +R
Sbjct: 139 LYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIR 198
Query: 602 ---------IRIITDAEE 576
+ I+TD EE
Sbjct: 199 DSERQGKAQVEIVTDGEE 216
>BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 67.3 bits (157), Expect = 6e-11
Identities = 54/188 (28%), Positives = 85/188 (45%), Gaps = 5/188 (2%)
Frame = -1
Query: 621 VRQSSTDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEA 442
V + D + GR RV + ++ + + LG E T +D R A
Sbjct: 243 VSKGIRDNERSGRARVHVSEE---GTEPEAMLQVLGPKPALPAGTEDTAKEDAA-NRKLA 298
Query: 441 SNVILSEVSDATGKIKVTPLS--KPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEK 271
L +VS+ G + V+ ++ PF Q L ++ +ILD G I+VW GKQA E+
Sbjct: 299 K---LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEER 355
Query: 270 SQAMTKAQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQ-- 97
A+ A + + +YP QV+ + + E FKQ+F WRD + + L +
Sbjct: 356 KAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIA 415
Query: 96 NKEKVP*D 73
N E+VP D
Sbjct: 416 NVERVPFD 423
Score = 50.4 bits (115), Expect = 7e-06
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ G+ + + QE+L+ + +LDT ++VW+GK + EK++A+T A+ +
Sbjct: 673 SNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKTEALTSAKRYI 731
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
N +T V Q EP +F +F W D
Sbjct: 732 ETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+FQ KG+R V +V S GD F+LD N+I+ + G + E+LKA + +R
Sbjct: 189 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 248
>BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 67.3 bits (157), Expect = 6e-11
Identities = 44/156 (28%), Positives = 74/156 (47%), Gaps = 3/156 (1%)
Frame = -1
Query: 603 DQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVILS 424
D + G+ +V+IV ++ + G K + E +D ++ A L
Sbjct: 199 DSERQGKAQVEIVTDGEEPAEMIQVL-----GPKPALK-EGNPEEDLTADKANAQAAALY 252
Query: 423 EVSDATGKIKVTPL--SKPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTK 253
+VSDATG++ +T + S PF E L + ++LD + G IY+W G++A E+ A+
Sbjct: 253 KVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQV 312
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWR 145
A+ + Y QV + Q E FKQ+F W+
Sbjct: 313 AEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDWK 348
Score = 37.9 bits (84), Expect = 0.041
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
++Q KGK+ + + S GD F+LD +I+ + G K+ +E+ KA A +R
Sbjct: 139 LYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIR 198
Query: 602 ---------IRIITDAEE 576
+ I+TD EE
Sbjct: 199 DSERQGKAQVEIVTDGEE 216
>BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 67.3 bits (157), Expect = 6e-11
Identities = 44/156 (28%), Positives = 74/156 (47%), Gaps = 3/156 (1%)
Frame = -1
Query: 603 DQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVILS 424
D + G+ +V+IV ++ + G K + E +D ++ A L
Sbjct: 199 DSERQGKAQVEIVTDGEEPAEMIQVL-----GPKPALK-EGNPEEDLTADKANAQAAALY 252
Query: 423 EVSDATGKIKVTPL--SKPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTK 253
+VSDATG++ +T + S PF E L + ++LD + G IY+W G++A E+ A+
Sbjct: 253 KVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQV 312
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWR 145
A+ + Y QV + Q E FKQ+F W+
Sbjct: 313 AEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDWK 348
Score = 37.9 bits (84), Expect = 0.041
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
++Q KGK+ + + S GD F+LD +I+ + G K+ +E+ KA A +R
Sbjct: 139 LYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIR 198
Query: 602 ---------IRIITDAEE 576
+ I+TD EE
Sbjct: 199 DSERQGKAQVEIVTDGEE 216
>AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 731
Score = 67.3 bits (157), Expect = 6e-11
Identities = 54/188 (28%), Positives = 85/188 (45%), Gaps = 5/188 (2%)
Frame = -1
Query: 621 VRQSSTDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEA 442
V + D + GR RV + ++ + + LG E T +D R A
Sbjct: 192 VSKGIRDNERSGRARVHVSEE---GTEPEAMLQVLGPKPALPAGTEDTAKEDAA-NRKLA 247
Query: 441 SNVILSEVSDATGKIKVTPLS--KPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEK 271
L +VS+ G + V+ ++ PF Q L ++ +ILD G I+VW GKQA E+
Sbjct: 248 K---LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEER 304
Query: 270 SQAMTKAQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQ-- 97
A+ A + + +YP QV+ + + E FKQ+F WRD + + L +
Sbjct: 305 KAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIA 364
Query: 96 NKEKVP*D 73
N E+VP D
Sbjct: 365 NVERVPFD 372
Score = 50.4 bits (115), Expect = 7e-06
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ G+ + + QE+L+ + +LDT ++VW+GK + EK++A+T A+ +
Sbjct: 622 SNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKTEALTSAKRYI 680
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
N +T V Q EP +F +F W D
Sbjct: 681 ETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 714
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+FQ KG+R V +V S GD F+LD N+I+ + G + E+LKA + +R
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
>AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 67.3 bits (157), Expect = 6e-11
Identities = 54/188 (28%), Positives = 85/188 (45%), Gaps = 5/188 (2%)
Frame = -1
Query: 621 VRQSSTDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEA 442
V + D + GR RV + ++ + + LG E T +D R A
Sbjct: 243 VSKGIRDNERSGRARVHVSEE---GTEPEAMLQVLGPKPALPAGTEDTAKEDAA-NRKLA 298
Query: 441 SNVILSEVSDATGKIKVTPLS--KPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEK 271
L +VS+ G + V+ ++ PF Q L ++ +ILD G I+VW GKQA E+
Sbjct: 299 K---LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEER 355
Query: 270 SQAMTKAQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQ-- 97
A+ A + + +YP QV+ + + E FKQ+F WRD + + L +
Sbjct: 356 KAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIA 415
Query: 96 NKEKVP*D 73
N E+VP D
Sbjct: 416 NVERVPFD 423
Score = 50.4 bits (115), Expect = 7e-06
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ G+ + + QE+L+ + +LDT ++VW+GK + EK++A+T A+ +
Sbjct: 673 SNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKTEALTSAKRYI 731
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
N +T V Q EP +F +F W D
Sbjct: 732 ETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+FQ KG+R V +V S GD F+LD N+I+ + G + E+LKA + +R
Sbjct: 189 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 248
>X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for
villin. ).
Length = 827
Score = 66.9 bits (156), Expect = 8e-11
Identities = 38/95 (40%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Frame = -1
Query: 429 LSEVSDATGKIKVTPLS-KPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTK 253
L VSD+ G + V ++ +P Q+ LS ++ YILD IYVW GK+A EK AM+
Sbjct: 255 LYHVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGLKIYVWKGKKANEQEKKGAMSH 314
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 148
A + AK YP QV E A F+Q F W
Sbjct: 315 ALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKW 349
Score = 60.9 bits (141), Expect = 5e-09
Identities = 41/125 (32%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Frame = -1
Query: 456 ERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATAN 277
E N L E S+ TG+ T + F Q++L + ++LD + ++ WIGK A
Sbjct: 612 EENLVITPRLFECSNKTGRFLATEIPD-FNQDDLEEDDVFLLD-VWDQVFFWIGKHANEE 669
Query: 276 EKSQAMTKAQELLGAKNYPSW----VQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*K 109
EK A T AQE L K +PS + V Q EP F +F W F S+++
Sbjct: 670 EKKAAATTAQEYL--KTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYED 727
Query: 108 LKAQN 94
LKA++
Sbjct: 728 LKAES 732
Score = 40.7 bits (91), Expect = 0.006
Identities = 19/60 (31%), Positives = 34/60 (56%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ KGKR V +V+ S +GDVF+LD I + G ++ +E+L+ ++ A ++R
Sbjct: 139 LLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIR 198
>BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein.
Length = 421
Score = 66.9 bits (156), Expect = 8e-11
Identities = 38/95 (40%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Frame = -1
Query: 429 LSEVSDATGKIKVTPLS-KPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTK 253
L VSD+ G + V ++ +P Q+ LS ++ YILD IYVW GK+A EK AM+
Sbjct: 255 LYHVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGLKIYVWKGKKANEQEKKGAMSH 314
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 148
A + AK YP QV E A F+Q F W
Sbjct: 315 ALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKW 349
Score = 40.7 bits (91), Expect = 0.006
Identities = 19/60 (31%), Positives = 34/60 (56%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ KGKR V +V+ S +GDVF+LD I + G ++ +E+L+ ++ A ++R
Sbjct: 139 LLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIR 198
>AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein.
Length = 827
Score = 66.9 bits (156), Expect = 8e-11
Identities = 38/95 (40%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Frame = -1
Query: 429 LSEVSDATGKIKVTPLS-KPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTK 253
L VSD+ G + V ++ +P Q+ LS ++ YILD IYVW GK+A EK AM+
Sbjct: 255 LYHVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGLKIYVWKGKKANEQEKKGAMSH 314
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 148
A + AK YP QV E A F+Q F W
Sbjct: 315 ALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKW 349
Score = 60.5 bits (140), Expect = 7e-09
Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 4/124 (3%)
Frame = -1
Query: 456 ERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATAN 277
E N L E S+ TG+ T + F Q++L + ++LD + ++ WIGK A
Sbjct: 612 EENLVITPRLFECSNKTGRFLATEIPD-FNQDDLEEDDVFLLD-VWDQVFFWIGKHANEE 669
Query: 276 EKSQAMTKAQELLGAKNYPSW----VQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*K 109
EK A T AQE L K +PS + V Q EP F +F W F S+++
Sbjct: 670 EKKAAATTAQEYL--KTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYED 727
Query: 108 LKAQ 97
LKA+
Sbjct: 728 LKAE 731
Score = 40.7 bits (91), Expect = 0.006
Identities = 19/60 (31%), Positives = 34/60 (56%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ KGKR V +V+ S +GDVF+LD I + G ++ +E+L+ ++ A ++R
Sbjct: 139 LLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIR 198
>AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 66.9 bits (156), Expect = 8e-11
Identities = 44/156 (28%), Positives = 74/156 (47%), Gaps = 3/156 (1%)
Frame = -1
Query: 603 DQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVILS 424
D + G+ +V+IV ++ + G K + E +D ++ A L
Sbjct: 199 DSERQGKAQVEIVTDGEEPAEMIQVL-----GPKPALK-EGNPEEDLTADKANAQAAALY 252
Query: 423 EVSDATGKIKVTPL--SKPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTK 253
+VSDATG++ +T + S PF E L + ++LD + G IY+W G++A E+ A+
Sbjct: 253 KVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQV 312
Query: 252 AQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWR 145
A+ + Y QV + Q E FKQ+F W+
Sbjct: 313 AEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
Score = 37.9 bits (84), Expect = 0.041
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
++Q KGK+ + + S GD F+LD +I+ + G K+ +E+ KA A +R
Sbjct: 139 LYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIR 198
Query: 602 ---------IRIITDAEE 576
+ I+TD EE
Sbjct: 199 DSERQGKAQVEIVTDGEE 216
>AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 485
Score = 66.1 bits (154), Expect = 1e-10
Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 5/124 (4%)
Frame = -1
Query: 429 LSEVSDATGKIKVTPLS--KPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAM 259
L +VS+ G + V+ ++ PF Q L ++ +ILD G I+VW GKQA E+ A+
Sbjct: 31 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAAL 90
Query: 258 TKAQELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQ--NKEK 85
A + + +YP QV+ + + E FKQ+F WRD + + L + N E+
Sbjct: 91 KTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVER 150
Query: 84 VP*D 73
VP D
Sbjct: 151 VPFD 154
Score = 38.7 bits (86), Expect = 0.023
Identities = 16/58 (27%), Positives = 33/58 (56%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQE 244
S+ G+ + + QE+L+ + +LDT ++VW+GK + EK++A+T ++
Sbjct: 404 SNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKTEALTSGED 460
>AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens
cDNA FLJ14872 fis, clone PLACE1002655, highly similar to
ADSEVERIN. ).
Length = 468
Score = 65.3 bits (152), Expect = 2e-10
Identities = 36/96 (37%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = -1
Query: 420 VSDATGKIKVTPLSK--PFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTKA 250
VSDA+G ++VT +++ PF L + +ILD + I+VW GK A E+ AM A
Sbjct: 7 VSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTA 66
Query: 249 QELLGAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
+E L NY Q+ + + E FKQ+F WRD
Sbjct: 67 EEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 102
Score = 43.6 bits (98), Expect = 8e-04
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++ A+ L
Sbjct: 373 SNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLKSAKMYL 431
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 148
+ + Q EP F +F W
Sbjct: 432 ETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 463
>BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein.
Length = 672
Score = 58.8 bits (136), Expect = 2e-08
Identities = 28/72 (38%), Positives = 40/72 (55%)
Frame = -1
Query: 357 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNYPSWVQVTRVLQNTEP 178
L ++ YILD IYVW G+ ++ E+ A ++A + AK YP++ V V E
Sbjct: 94 LQEEDFYILDQGGFKIYVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAES 153
Query: 177 AAFKQYFFTWRD 142
AAFKQ F TW +
Sbjct: 154 AAFKQLFRTWSE 165
Score = 40.3 bits (90), Expect = 0.008
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Frame = -1
Query: 372 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNYPSW----VQV 205
F QE+L + +LDT I++W+G+ A+E +A+ QE L K +P+ +
Sbjct: 448 FSQEDLDKYDIMLLDTWQ-EIFLWLGE--AASEWKEAVAWGQEYL--KTHPAGRSPATPI 502
Query: 204 TRVLQNTEPAAFKQYFFTW 148
V Q EP F +FFTW
Sbjct: 503 VLVKQGHEPPTFIGWFFTW 521
>BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin
(amyloidosis, Finnish type) protein.
Length = 285
Score = 50.4 bits (115), Expect = 7e-06
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ G+ + + QE+L+ + +LDT ++VW+GK + EK++A+T A+ +
Sbjct: 176 SNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKTEALTSAKRYI 234
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
N +T V Q EP +F +F W D
Sbjct: 235 ETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 268
>AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 207
Score = 50.4 bits (115), Expect = 7e-06
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ G+ + + QE+L+ + +LDT ++VW+GK + EK++A+T A+ +
Sbjct: 98 SNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKTEALTSAKRYI 156
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 142
N +T V Q EP +F +F W D
Sbjct: 157 ETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 190
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/87 (31%), Positives = 46/87 (52%)
Frame = -1
Query: 402 KIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNY 223
K+++ P + Q L + YILD S ++++W+G+++ ++ A+ QEL G +
Sbjct: 756 KVELMPRMR-LLQSLLDTRCVYILDCWS-DVFIWLGRKSPRLVRAAALKLGQELCGMLHR 813
Query: 222 PSWVQVTRVLQNTEPAAFKQYFFTWRD 142
P V+R L+ TE FK F W D
Sbjct: 814 PRHATVSRSLEGTEAQVFKAKFKNWDD 840
Score = 34.7 bits (76), Expect = 0.38
Identities = 24/77 (31%), Positives = 39/77 (50%)
Frame = -1
Query: 399 IKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNYP 220
IK+ P+ P K +L P+ ++LD +IYVW G QAT + ++A A E +
Sbjct: 630 IKLEPV--PLKGTSLDPRFVFLLDR-GLDIYVWRGAQATLSSTTKARLFA-EKINKNERK 685
Query: 219 SWVQVTRVLQNTEPAAF 169
++T ++Q E F
Sbjct: 686 GKAEITLLVQGQELPEF 702
Score = 32.7 bits (71), Expect = 1.5
Identities = 19/59 (32%), Positives = 31/59 (52%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQV 606
M++ GK+ + + V + S+ VF+LD DIYV+ G +A KA FA ++
Sbjct: 621 MYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKI 679
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog protein.
Length = 1268
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/87 (31%), Positives = 46/87 (52%)
Frame = -1
Query: 402 KIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNY 223
K+++ P + Q L + YILD S ++++W+G+++ ++ A+ QEL G +
Sbjct: 755 KVELMPRMR-LLQSLLDTRCVYILDCWS-DVFIWLGRKSPRLVRAAALKLGQELCGMLHR 812
Query: 222 PSWVQVTRVLQNTEPAAFKQYFFTWRD 142
P V+R L+ TE FK F W D
Sbjct: 813 PRHATVSRSLEGTEAQVFKAKFKNWDD 839
Score = 34.7 bits (76), Expect = 0.38
Identities = 24/77 (31%), Positives = 39/77 (50%)
Frame = -1
Query: 399 IKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNYP 220
IK+ P+ P K +L P+ ++LD +IYVW G QAT + ++A A E +
Sbjct: 629 IKLEPV--PLKGTSLDPRFVFLLDR-GLDIYVWRGAQATLSSTTKARLFA-EKINKNERK 684
Query: 219 SWVQVTRVLQNTEPAAF 169
++T ++Q E F
Sbjct: 685 GKAEITLLVQGQELPEF 701
Score = 32.7 bits (71), Expect = 1.5
Identities = 19/59 (32%), Positives = 31/59 (52%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQV 606
M++ GK+ + + V + S+ VF+LD DIYV+ G +A KA FA ++
Sbjct: 620 MYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKI 678
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/87 (31%), Positives = 46/87 (52%)
Frame = -1
Query: 402 KIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNY 223
K+++ P + Q L + YILD S ++++W+G+++ ++ A+ QEL G +
Sbjct: 756 KVELMPRMR-LLQSLLDTRCVYILDCWS-DVFIWLGRKSPRLVRAAALKLGQELCGMLHR 813
Query: 222 PSWVQVTRVLQNTEPAAFKQYFFTWRD 142
P V+R L+ TE FK F W D
Sbjct: 814 PRHATVSRSLEGTEAQVFKAKFKNWDD 840
Score = 34.7 bits (76), Expect = 0.38
Identities = 24/77 (31%), Positives = 39/77 (50%)
Frame = -1
Query: 399 IKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNYP 220
IK+ P+ P K +L P+ ++LD +IYVW G QAT + ++A A E +
Sbjct: 630 IKLEPV--PLKGTSLDPRFVFLLDR-GLDIYVWRGAQATLSSTTKARLFA-EKINKNERK 685
Query: 219 SWVQVTRVLQNTEPAAF 169
++T ++Q E F
Sbjct: 686 GKAEITLLVQGQELPEF 702
Score = 32.7 bits (71), Expect = 1.5
Identities = 19/59 (32%), Positives = 31/59 (52%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQV 606
M++ GK+ + + V + S+ VF+LD DIYV+ G +A KA FA ++
Sbjct: 621 MYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKI 679
>AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 260
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+FQ KG+R V +V S GD F+LD N+I+ + G + E+LKA + +R
Sbjct: 138 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 197
>AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 228
Score = 45.6 bits (103), Expect = 2e-04
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+FQ KG+R V +V S GD F+LD N+I+ + G + E+LKA + +R
Sbjct: 149 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 208
>AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/62 (33%), Positives = 37/62 (59%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ Q KG+R V R V+P+ +++ GD F+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 602 IR 597
+
Sbjct: 1505 TK 1506
Score = 27.5 bits (58), Expect(2) = 0.18
Identities = 14/45 (31%), Positives = 23/45 (51%)
Frame = -1
Query: 222 PSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQNKE 88
P W R+ ++ E FK+ F W + S+ + +L AQ+KE
Sbjct: 1658 PDWAIFGRLTEHNETILFKEKFLDWTELKRSNEKNPGEL-AQHKE 1701
Score = 27.1 bits (57), Expect(2) = 0.18
Identities = 12/39 (30%), Positives = 19/39 (48%)
Frame = -1
Query: 357 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQEL 241
L P+ + D +YVW GK+ T ++ A A+ L
Sbjct: 1589 LQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAFQLAKHL 1626
>AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/62 (33%), Positives = 37/62 (59%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ Q KG+R V R V+P+ +++ GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 602 IR 597
+
Sbjct: 1079 TK 1080
Score = 27.5 bits (58), Expect(2) = 0.18
Identities = 14/45 (31%), Positives = 23/45 (51%)
Frame = -1
Query: 222 PSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQNKE 88
P W R+ ++ E FK+ F W + S+ + +L AQ+KE
Sbjct: 1232 PDWAIFGRLTEHNETILFKEKFLDWTELKRSNEKNPGEL-AQHKE 1275
Score = 27.1 bits (57), Expect(2) = 0.18
Identities = 12/39 (30%), Positives = 19/39 (48%)
Frame = -1
Query: 357 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQEL 241
L P+ + D +YVW GK+ T ++ A A+ L
Sbjct: 1163 LQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAFQLAKHL 1200
>AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/62 (33%), Positives = 37/62 (59%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ Q KG+R V R V+P+ +++ GD F+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 602 IR 597
+
Sbjct: 1505 TK 1506
Score = 27.5 bits (58), Expect(2) = 0.18
Identities = 14/45 (31%), Positives = 23/45 (51%)
Frame = -1
Query: 222 PSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQNKE 88
P W R+ ++ E FK+ F W + S+ + +L AQ+KE
Sbjct: 1658 PDWAIFGRLTEHNETILFKEKFLDWTELKRSNEKNPGEL-AQHKE 1701
Score = 27.1 bits (57), Expect(2) = 0.18
Identities = 12/39 (30%), Positives = 19/39 (48%)
Frame = -1
Query: 357 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQEL 241
L P+ + D +YVW GK+ T ++ A A+ L
Sbjct: 1589 LQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAFQLAKHL 1626
>AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/62 (33%), Positives = 37/62 (59%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ Q KG+R V R V+P+ +++ GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 602 IR 597
+
Sbjct: 1079 TK 1080
Score = 27.5 bits (58), Expect(2) = 0.18
Identities = 14/45 (31%), Positives = 23/45 (51%)
Frame = -1
Query: 222 PSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQNKE 88
P W R+ ++ E FK+ F W + S+ + +L AQ+KE
Sbjct: 1232 PDWAIFGRLTEHNETILFKEKFLDWTELKRSNEKNPGEL-AQHKE 1275
Score = 27.1 bits (57), Expect(2) = 0.18
Identities = 12/39 (30%), Positives = 19/39 (48%)
Frame = -1
Query: 357 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQEL 241
L P+ + D +YVW GK+ T ++ A A+ L
Sbjct: 1163 LQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAFQLAKHL 1200
>AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.
Length = 2214
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/62 (33%), Positives = 37/62 (59%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ Q KG+R V R V+P+ +++ GD F+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 602 IR 597
+
Sbjct: 1505 TK 1506
Score = 27.5 bits (58), Expect(2) = 0.18
Identities = 14/45 (31%), Positives = 23/45 (51%)
Frame = -1
Query: 222 PSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQNKE 88
P W R+ ++ E FK+ F W + S+ + +L AQ+KE
Sbjct: 1658 PDWAIFGRLTEHNETILFKEKFLDWTELKRSNEKNPGEL-AQHKE 1701
Score = 27.1 bits (57), Expect(2) = 0.18
Identities = 12/39 (30%), Positives = 19/39 (48%)
Frame = -1
Query: 357 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQEL 241
L P+ + D +YVW GK+ T ++ A A+ L
Sbjct: 1589 LQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAFQLAKHL 1626
>AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/62 (33%), Positives = 37/62 (59%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ Q KG+R V R V+P+ +++ GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 602 IR 597
+
Sbjct: 1079 TK 1080
Score = 27.5 bits (58), Expect(2) = 0.18
Identities = 14/45 (31%), Positives = 23/45 (51%)
Frame = -1
Query: 222 PSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQNKE 88
P W R+ ++ E FK+ F W + S+ + +L AQ+KE
Sbjct: 1232 PDWAIFGRLTEHNETILFKEKFLDWTELKRSNEKNPGEL-AQHKE 1275
Score = 27.1 bits (57), Expect(2) = 0.18
Identities = 12/39 (30%), Positives = 19/39 (48%)
Frame = -1
Query: 357 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQEL 241
L P+ + D +YVW GK+ T ++ A A+ L
Sbjct: 1163 LQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAFQLAKHL 1200
>AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/62 (33%), Positives = 37/62 (59%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQVR 603
+ Q KG+R V R V+P+ +++ GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 602 IR 597
+
Sbjct: 1079 TK 1080
Score = 27.5 bits (58), Expect(2) = 0.18
Identities = 14/45 (31%), Positives = 23/45 (51%)
Frame = -1
Query: 222 PSWVQVTRVLQNTEPAAFKQYFFTWRDFGMSHSRVI*KLKAQNKE 88
P W R+ ++ E FK+ F W + S+ + +L AQ+KE
Sbjct: 1232 PDWAIFGRLTEHNETILFKEKFLDWTELKRSNEKNPGEL-AQHKE 1275
Score = 27.1 bits (57), Expect(2) = 0.18
Identities = 12/39 (30%), Positives = 19/39 (48%)
Frame = -1
Query: 357 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQEL 241
L P+ + D +YVW GK+ T ++ A A+ L
Sbjct: 1163 LQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAFQLAKHL 1200
>AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ90717 fis, clone PLACE1008657, highly similar to
Bovine mRNA for adseverin. ).
Length = 396
Score = 43.6 bits (98), Expect = 8e-04
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = -1
Query: 417 SDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL 238
S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++ A+ L
Sbjct: 301 SNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLKSAKMYL 359
Query: 237 --GAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 148
+ + Q EP F +F W
Sbjct: 360 ETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 391
>AB209574-1|BAD92811.1| 326|Homo sapiens villin-like variant
protein.
Length = 326
Score = 40.3 bits (90), Expect = 0.008
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Frame = -1
Query: 372 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNYPSW----VQV 205
F QE+L + +LDT I++W+G+ A+E +A+ QE L K +P+ +
Sbjct: 194 FSQEDLDKYDIMLLDTWQ-EIFLWLGE--AASEWKEAVAWGQEYL--KTHPAGRSPATPI 248
Query: 204 TRVLQNTEPAAFKQYFFTW 148
V Q EP F +FFTW
Sbjct: 249 VLVKQGHEPPTFIGWFFTW 267
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 34.7 bits (76), Expect = 0.38
Identities = 24/77 (31%), Positives = 39/77 (50%)
Frame = -1
Query: 399 IKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLGAKNYP 220
IK+ P+ P K +L P+ ++LD +IYVW G QAT + ++A A E +
Sbjct: 617 IKLEPV--PLKGTSLDPRFVFLLDR-GLDIYVWRGAQATLSSTTKARLFA-EKINKNERK 672
Query: 219 SWVQVTRVLQNTEPAAF 169
++T ++Q E F
Sbjct: 673 GKAEITLLVQGQELPEF 689
Score = 32.7 bits (71), Expect = 1.5
Identities = 19/59 (32%), Positives = 31/59 (52%)
Frame = -2
Query: 782 MFQXKGKRXVXVRQVDPQIASMXKGDVFVLDXDNDIYVFVGEKAKNVEKLKAISFANQV 606
M++ GK+ + + V + S+ VF+LD DIYV+ G +A KA FA ++
Sbjct: 608 MYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKI 666
>DQ012935-1|AAY22174.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2 protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 439 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 311
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>BC112342-1|AAI12343.1| 1553|Homo sapiens TRPM2 protein protein.
Length = 1553
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 439 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 311
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AY603182-1|AAT12288.1| 846|Homo sapiens TRPM2-S protein.
Length = 846
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 439 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 311
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AP001754-4|BAA95563.1| 1503|Homo sapiens transient receptor
potential-related channel 7, a novel putative Ca2+
channel p protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 439 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 311
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AJ878416-1|CAI47593.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2 protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 439 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 311
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AJ417076-1|CAD01139.1| 1449|Homo sapiens putative TRP cation
channel protein.
Length = 1449
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 439 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 311
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AB166746-1|BAD83706.1| 1289|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2,
striatum sh protein.
Length = 1289
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 439 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 311
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 197 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 240
>AB166745-1|BAD83705.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2, long
form ( protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 439 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 311
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AB001535-1|BAA34700.1| 1503|Homo sapiens KNP3 protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.5
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 439 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 311
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>BC129991-1|AAI29992.1| 754|Homo sapiens PERQ1 protein protein.
Length = 754
Score = 30.3 bits (65), Expect = 8.2
Identities = 23/77 (29%), Positives = 35/77 (45%)
Frame = -1
Query: 579 RVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGK 400
R+D D+ D F L G K+ +P+E D Q E E + L E G
Sbjct: 14 RLDDEDEEMGTFDASGAFLPLKKGPKEPIPEEQE-LDFQGLEEEEEPSEGLEEEGPEAGG 72
Query: 399 IKVTPLSKPFKQENLSP 349
++TPL P ++++ SP
Sbjct: 73 KELTPL-PPQEEKSSSP 88
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,450,664
Number of Sequences: 237096
Number of extensions: 1887165
Number of successful extensions: 4115
Number of sequences better than 10.0: 50
Number of HSP's better than 10.0 without gapping: 3820
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4098
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9534535578
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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