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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= FWDP01_FL5_E11
         (847 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   193   4e-48
UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome s...   149   7e-35
UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH...   127   4e-28
UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albica...   120   6e-26
UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;...   117   3e-25
UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1; ...   116   1e-24
UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; ...   112   1e-23
UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   105   1e-21
UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC...   104   2e-21
UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole gen...    61   2e-18
UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridipla...    59   2e-17
UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    89   1e-16
UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergil...    75   2e-12
UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    75   2e-12
UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, who...    75   3e-12
UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    70   6e-11
UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    69   2e-10
UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacte...    67   6e-10
UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    66   1e-09
UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    63   7e-09
UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    61   3e-08
UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1; Opitut...    44   3e-08
UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    60   7e-08
UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1...    60   9e-08
UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    59   2e-07
UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    58   4e-07
UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n...    54   3e-06
UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E...    53   1e-05
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    52   2e-05
UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni...    50   6e-05
UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr...    50   1e-04
UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    49   2e-04
UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    48   3e-04
UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;...    48   4e-04
UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n...    47   7e-04
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    46   0.001
UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 compone...    46   0.001
UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    46   0.002
UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    45   0.002
UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    44   0.004
UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;...    44   0.004
UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni...    43   0.008
UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    42   0.026
UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    42   0.026
UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    41   0.045
UniRef50_A5XEI0 Cluster: Oxoglutarate (Alpha-ketoglutarate) dehy...    39   0.14 
UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ...    39   0.18 
UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    38   0.32 
UniRef50_Q2JFB9 Cluster: Putative uncharacterized protein; n=1; ...    37   0.73 
UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    36   0.97 
UniRef50_Q8UDS8 Cluster: Short chain dehydrogenase; n=1; Agrobac...    36   1.3  
UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, p...    36   1.7  
UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    36   1.7  
UniRef50_Q02C37 Cluster: Putative uncharacterized protein; n=1; ...    35   2.2  
UniRef50_UPI0000F2D68A Cluster: PREDICTED: hypothetical protein;...    35   3.0  
UniRef50_Q0RQH6 Cluster: Putative LuxR-family transcriptional re...    35   3.0  
UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    35   3.0  
UniRef50_A0LLC1 Cluster: Putative uncharacterized protein; n=1; ...    35   3.0  
UniRef50_A5DZM2 Cluster: Putative uncharacterized protein; n=1; ...    34   3.9  
UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1;...    34   5.2  
UniRef50_A7QD53 Cluster: Chromosome undetermined scaffold_80, wh...    34   5.2  
UniRef50_Q4QJD5 Cluster: Putative uncharacterized protein; n=2; ...    34   5.2  
UniRef50_UPI0000DD7C6C Cluster: PREDICTED: hypothetical protein;...    33   6.8  
UniRef50_Q395C1 Cluster: Rhs family protein; n=6; Burkholderia|R...    33   6.8  
UniRef50_A4U1B6 Cluster: Secreted protein; n=1; Magnetospirillum...    33   6.8  
UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase,...    33   6.8  
UniRef50_Q5K6W4 Cluster: Putative uncharacterized protein; n=1; ...    33   6.8  
UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    33   6.8  
UniRef50_Q13118 Cluster: Krueppel-like factor 10; n=35; Amniota|...    33   6.8  
UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspar...    33   9.0  
UniRef50_Q2JGL1 Cluster: Rieske (2Fe-2S) protein; n=7; Actinomyc...    33   9.0  
UniRef50_A1IAX2 Cluster: Outer membrane lipoprotein-sorting prot...    33   9.0  
UniRef50_Q8S6C0 Cluster: Putative uncharacterized protein OJ1004...    33   9.0  
UniRef50_Q01A93 Cluster: Chromosome 04 contig 1, DNA sequence; n...    33   9.0  
UniRef50_Q55GQ4 Cluster: Putative uncharacterized protein; n=1; ...    33   9.0  
UniRef50_Q9UU85 Cluster: Protein kinase domain-containing protei...    33   9.0  
UniRef50_Q4IER0 Cluster: Leucine carboxyl methyltransferase 2; n...    33   9.0  

>UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 component,
           mitochondrial precursor; n=77; Eumetazoa|Rep:
           2-oxoglutarate dehydrogenase E1 component, mitochondrial
           precursor - Homo sapiens (Human)
          Length = 1002

 Score =  193 bits (471), Expect = 4e-48
 Identities = 117/269 (43%), Positives = 148/269 (55%), Gaps = 3/269 (1%)
 Frame = +3

Query: 21  NKPQTAAVSVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATN 200
           N+P  A          +  AAEPFL+G+SS YVE MY AWL +P SVH SWD FFRN   
Sbjct: 26  NRPAAARTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNA 85

Query: 201 GAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRS 380
           GA PG AY  P    P ++  +   +   S      +    P  +K+++DHLAVQ++IR+
Sbjct: 86  GAPPGTAYQSP---LPLSRGSLAAVAHAQS------LVEAQPNVDKLVEDHLAVQSLIRA 136

Query: 381 YQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPST 560
           YQ RGH VAQLDPLGI   D  SS           +          DE+D+D+VF LP+T
Sbjct: 137 YQIRGHHVAQLDPLGILDADLDSSVP-----ADIISSTDKLGFYGLDESDLDKVFHLPTT 191

Query: 561 TFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLETMQ---LDPTAHGATERNKDER 731
           TFIG +E ALPLREI+ RLE AYC +IG+EFMFIN LE  Q         G  +   +E+
Sbjct: 192 TFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEK 251

Query: 732 *PEEAHPGSSNQINWVREFPR*KWSSEXR 818
               A    S +     EF + KWSSE R
Sbjct: 252 RTLLARLVRSTRF---EEFLQRKWSSEKR 277


>UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome
           shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 17
           SCAF14563, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1054

 Score =  149 bits (362), Expect = 7e-35
 Identities = 89/216 (41%), Positives = 115/216 (53%)
 Frame = +3

Query: 36  AAVSVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPG 215
           AA  V+     S     P    S+ +YVE MY +WL DP SVH SWD FFRN        
Sbjct: 38  AAGVVDRRSCSSGAVTGPSALTSNPSYVEEMYFSWLEDPKSVHKSWDMFFRNMEASPSGE 97

Query: 216 AAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRG 395
           AA   P  L                     ++S  S + +K+++DHLAV  +IR+YQ+RG
Sbjct: 98  AADRRPSTLLRGR-----------------TLSHSSDVAQKVVEDHLAVHTLIRAYQTRG 140

Query: 396 HLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGE 575
           H VAQLDPLGI   D  S                   +    E+D+DR F+LPSTTFIG 
Sbjct: 141 HHVAQLDPLGILEADLDSFVP-----SDLITSIDKLGYYDLKESDLDRSFQLPSTTFIGG 195

Query: 576 KEKALPLREILNRLEQAYCNNIGIEFMFINSLETMQ 683
           ++  LPLREI+ RLE AYC +IG+EFMFIN+++  Q
Sbjct: 196 EDSTLPLREIIRRLEMAYCGHIGVEFMFINNVDQCQ 231



 Score = 50.4 bits (115), Expect = 6e-05
 Identities = 21/41 (51%), Positives = 28/41 (68%)
 Frame = +1

Query: 676 QCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAK 798
           QC WIR ++E P + +     KR +LARL RST FE+FLA+
Sbjct: 229 QCQWIRNKIETPGIMRFTDADKRTLLARLIRSTRFEDFLAR 269


>UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH
           protein - Homo sapiens (Human)
          Length = 640

 Score =  127 bits (306), Expect = 4e-28
 Identities = 82/179 (45%), Positives = 106/179 (59%), Gaps = 14/179 (7%)
 Frame = +3

Query: 324 PINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSS--ADWHGGMRAFANEAV 497
           P  +K+++DHLAVQ++IR+YQ RGH VAQLDPLGI   D  SS  AD         + AV
Sbjct: 9   PNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKL-DLAV 67

Query: 498 IRQHVRF---------DEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIE 650
            ++ +R          DE+D+D+VF LP+TTFIG +E ALPLREI+ RLE AYC +IG+E
Sbjct: 68  FKERLRMLTVGGFYGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVE 127

Query: 651 FMFINSLETMQ---LDPTAHGATERNKDER*PEEAHPGSSNQINWVREFPR*KWSSEXR 818
           FMFIN LE  Q         G  +   +E+    A    S +     EF + KWSSE R
Sbjct: 128 FMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRF---EEFLQRKWSSEKR 183


>UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albicans
           CaKGD1 2-oxoglutarate dehydrogenase; n=4;
           Ascomycota|Rep: Similar to CA3149|CaKGD1 Candida
           albicans CaKGD1 2-oxoglutarate dehydrogenase -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 997

 Score =  120 bits (288), Expect = 6e-26
 Identities = 72/205 (35%), Positives = 109/205 (53%), Gaps = 4/205 (1%)
 Frame = +3

Query: 72  STAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNA-TNGAQPGAAYTPPPNLAP 248
           +T  + FL  +++ Y++ MY AW  DP+SVH SW+A+F+N  ++   P  A+T PP + P
Sbjct: 27  ATGQDSFLLSNNANYIDEMYAAWKHDPSSVHISWNAYFKNIESSNVPPSKAFTAPPTIIP 86

Query: 249 YNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGI 428
                        + G    +   SP NE ++  HL VQ ++R+YQ RGH  A++DPLGI
Sbjct: 87  -----------TVAGGAAGFVPGSSPTNEDVVT-HLKVQLLVRAYQVRGHQKAKIDPLGI 134

Query: 429 STGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKL-PSTT--FIGEKEKALPLR 599
           S GD                + +  +H  F EADMD+   L P     F    +K+L LR
Sbjct: 135 SFGD-----------NDVVPKELTLEHYGFTEADMDKQITLGPGILPRFAEGGKKSLTLR 183

Query: 600 EILNRLEQAYCNNIGIEFMFINSLE 674
           EI++  E+ YC + G+E++ I S E
Sbjct: 184 EIISNCERLYCQSYGVEYIHIPSKE 208



 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 24/49 (48%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
 Frame = +1

Query: 664 IPWK-QCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKNGP 807
           IP K QC+W+R+R+E P   K + D+KR IL R+  S  FE+FLA   P
Sbjct: 204 IPSKEQCDWLRERIEIPEPYKYSPDEKRQILDRVIWSCSFESFLASKFP 252


>UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;
           n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
           protein - Nasonia vitripennis
          Length = 1012

 Score =  117 bits (282), Expect = 3e-25
 Identities = 74/228 (32%), Positives = 113/228 (49%), Gaps = 12/228 (5%)
 Frame = +3

Query: 84  EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNE 263
           + FL  +SS Y+E +++ W  DP+SV  SWD +FR   +GA  G +       +     +
Sbjct: 31  DSFLTQTSSQYIEHLFSKWRKDPSSVPESWDVYFRKVESGAPLGPSPRKSSLKSSSKMQD 90

Query: 264 VPLTSLVPSS-----GGMPSISAGSPIN---EKIIDDHLAVQAIIRSYQSRGHLVAQLDP 419
           VP   L            P +   S      E  ++  L + A IRSYQ+RGHL+A +DP
Sbjct: 91  VPANLLGAQRIEYDLMTKPRVRLKSEAEIQGEAYVESTLDINATIRSYQARGHLIADIDP 150

Query: 420 LGISTGDPVSSADWHGGMRAFANEAVIRQHVR-FDEADMDRVFKLPSTTFIGEKEKALPL 596
           LGI   D     +            V+R+H++   E D++R F L + T IG   + LPL
Sbjct: 151 LGIQNPDSARLQNTSD----LPPRLVVREHLKGMTETDLNREFPLGTITVIGGDRETLPL 206

Query: 597 REILNRLEQAYCNNIGIEFMFINS---LETMQLDPTAHGATERNKDER 731
           REI+ RL + YC ++G+E+++I+    LE ++      GA E   D R
Sbjct: 207 REIIKRLNKVYCGHLGLEYIYIHDSTVLEWLRYKFEIPGAWELAADHR 254



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 14/38 (36%), Positives = 23/38 (60%)
 Frame = +1

Query: 685 WIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAK 798
           W+R + E P   ++ AD ++ I   + ++  FENFLAK
Sbjct: 236 WLRYKFEIPGAWELAADHRKWIWVNIMKAVTFENFLAK 273


>UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 334

 Score =  116 bits (278), Expect = 1e-24
 Identities = 79/231 (34%), Positives = 123/231 (53%), Gaps = 9/231 (3%)
 Frame = +3

Query: 9   SWLLNKPQTAAVSVNANRLKSSTAA-----EPFLNGSSSAYVETMYNAWLADPNSVHASW 173
           S L +K ++ A+ ++  R +S+TA+     + FL+G+++ Y++ MY  W  DP+SVH SW
Sbjct: 35  SALSSKRRSLAI-ISQKRHESTTASATDLNDSFLSGNTANYIDEMYMQWKEDPSSVHISW 93

Query: 174 DAFFRNATNGAQP-GAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDD 350
             +FRN  +G  P   A+TPPP L P     VP  S +P  GG    + GS +      +
Sbjct: 94  QVYFRNMESGDMPMSQAFTPPPTLVPTPTGGVP--SFLPGLGG----AEGSEVT-----N 142

Query: 351 HLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEAD 530
           HL VQ + R+YQ+RGH  A +DPLGI        A+  G  +    + +  +H +F E D
Sbjct: 143 HLKVQLLCRAYQARGHHKADIDPLGIR-----REAEEFGYSKP---KELQLEHYQFSEKD 194

Query: 531 MDRVFKL-PSTT--FIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLE 674
           +D  + L P     F     + + LREI+   E+ YC + G+E++ I   E
Sbjct: 195 LDTEYSLGPGILPHFKKSGREKMTLREIIAACERIYCGSYGVEYIHIPDRE 245



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 21/45 (46%), Positives = 29/45 (64%)
 Frame = +1

Query: 673 KQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKNGP 807
           +QC+W+R R+E     K + D+KR IL RL  S+ FE+FLA   P
Sbjct: 245 EQCDWLRARIEVDKPFKYSIDEKRRILDRLIWSSSFESFLATKYP 289


>UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1013

 Score =  112 bits (269), Expect = 1e-23
 Identities = 71/201 (35%), Positives = 104/201 (51%), Gaps = 3/201 (1%)
 Frame = +3

Query: 81  AEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKN 260
           +E FL+G+SS YVE M+  W+ DP SVH SW +FF ++  G   G A+  PP L      
Sbjct: 45  SESFLDGTSSTYVEDMFANWVKDPKSVHPSWASFFESSERGVPAGEAFMSPPTL-----G 99

Query: 261 EVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGD 440
               T   PS+      S+GSP   K + D + +  ++R+YQ RGH +A LDPLG+   +
Sbjct: 100 SSVATKATPST----YTSSGSP---KQVSDSMRLLLLVRAYQVRGHALANLDPLGLEVKE 152

Query: 441 PVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPS---TTFIGEKEKALPLREILN 611
               A+++     F             EADMDR   +     + F+  K+    LR++L 
Sbjct: 153 --EPAEFNPAKYGFT------------EADMDRPIFVGEGFISGFLTNKQPETTLRQVLK 198

Query: 612 RLEQAYCNNIGIEFMFINSLE 674
           RL++ YC +IGIE+M I   E
Sbjct: 199 RLKETYCGDIGIEYMHIQDRE 219


>UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 component,
           mitochondrial precursor; n=34; Fungi/Metazoa group|Rep:
           2-oxoglutarate dehydrogenase E1 component, mitochondrial
           precursor - Saccharomyces cerevisiae (Baker's yeast)
          Length = 1014

 Score =  105 bits (253), Expect = 1e-21
 Identities = 66/204 (32%), Positives = 109/204 (53%), Gaps = 4/204 (1%)
 Frame = +3

Query: 69  SSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGA-AYTPPPNLA 245
           ++T  + FL+ S++ Y++ MY AW  DP+SVH SWDA+F+N +N   P   A+  PP+++
Sbjct: 37  ATTGTDNFLSTSNATYIDEMYQAWQKDPSSVHVSWDAYFKNMSNPKIPATKAFQAPPSIS 96

Query: 246 PYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLG 425
            + +     T   P    M     GS ++E  +  HL VQ + R+YQ RGHL A +DPLG
Sbjct: 97  NFPQG----TEAAPLGTAM----TGS-VDEN-VSIHLKVQLLCRAYQVRGHLKAHIDPLG 146

Query: 426 ISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKL-PS--TTFIGEKEKALPL 596
           IS G   ++              +   +  F + D+D+   L P     F  + +  + L
Sbjct: 147 ISFGSNKNNP---------VPPELTLDYYGFSKHDLDKEINLGPGILPRFARDGKSKMSL 197

Query: 597 REILNRLEQAYCNNIGIEFMFINS 668
           +EI++ LE+ YC++ G+++  I S
Sbjct: 198 KEIVDHLEKLYCSSYGVQYTHIPS 221



 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 25/49 (51%), Positives = 33/49 (67%), Gaps = 1/49 (2%)
 Frame = +1

Query: 664 IPWKQ-CNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKNGP 807
           IP KQ C+W+R+R+E P   +   DQKR IL RLT +T FE+FL+   P
Sbjct: 219 IPSKQKCDWLRERIEIPEPYQYTVDQKRQILDRLTWATSFESFLSTKFP 267


>UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC,
           isoform C; n=1; Apis mellifera|Rep: PREDICTED: similar
           to CG33791-PC, isoform C - Apis mellifera
          Length = 980

 Score =  104 bits (250), Expect = 2e-21
 Identities = 65/194 (33%), Positives = 101/194 (52%), Gaps = 5/194 (2%)
 Frame = +3

Query: 105 SSAYVETMYNAWLADPNSVHASWDAFFR---NATNGAQPGAAYTPPPNLAPYNKNEVPLT 275
           S  Y+E MY +W  DP+SV  SW+ +F+        ++  +  + P + +       P +
Sbjct: 3   SIQYLEYMYQSWKKDPSSVSDSWNRYFKLIDEKDKKSEAASHKSSPKSTSSSTHGGSPSS 62

Query: 276 SLVPSSGGMPSISAGSPIN-EKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSS 452
               S        + S +  +K I     + A IR+YQ+RGHL+A  DPLGI   +P S 
Sbjct: 63  QSTKSPEQNAKSKSNSDMQGDKYIIGAFDINATIRAYQARGHLIADTDPLGIQ--NPESR 120

Query: 453 ADWHGGMRAFANEAVIRQHVR-FDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629
                G        V+RQ+++   EADM+R F L   T IG  +++LPLR+IL RL Q Y
Sbjct: 121 K--LQGTPNLPPAIVVRQYLKGMTEADMNREFPLAPFTVIGGSKRSLPLRDILIRLNQVY 178

Query: 630 CNNIGIEFMFINSL 671
           C ++G+E+ +I+ L
Sbjct: 179 CGHLGLEYTYIHDL 192



 Score = 34.3 bits (75), Expect = 3.9
 Identities = 13/42 (30%), Positives = 23/42 (54%)
 Frame = +1

Query: 682 NWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKNGP 807
           +W+R + E P    + AD ++ I   + ++  FE FLA+  P
Sbjct: 196 DWLRDKFEIPGAWDLPADHRKFIWMNIMKAVTFEGFLARKFP 237


>UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr13 scaffold_17, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 973

 Score = 60.9 bits (141), Expect(2) = 2e-18
 Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 4/121 (3%)
 Frame = +3

Query: 312 SAGSP-INEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFAN 488
           +A SP I+ + I + + +  ++R+YQ  GH+ A+LDPLG+   +     D          
Sbjct: 107 AATSPGISGQTIQESMRLLLLVRAYQVNGHMKAKLDPLGLEEREIPDDLD---------- 156

Query: 489 EAVIRQHVRFDEADMDRVFKLP---STTFIGEKEKALPLREILNRLEQAYCNNIGIEFMF 659
            A+      F EAD+DR F L       F+ E      LR IL RLEQAYC +IG E+M 
Sbjct: 157 PALYG----FTEADLDREFFLGVWRMAGFLSENRPVQTLRAILTRLEQAYCGSIGYEYMH 212

Query: 660 I 662
           I
Sbjct: 213 I 213



 Score = 54.4 bits (125), Expect(2) = 2e-18
 Identities = 23/40 (57%), Positives = 28/40 (70%)
 Frame = +3

Query: 72  STAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRN 191
           S   + FL+G+SS Y+E +  AW ADPNSV  SWD FFRN
Sbjct: 63  SRLTDSFLDGTSSVYLEELQRAWEADPNSVDESWDNFFRN 102



 Score = 45.6 bits (103), Expect = 0.002
 Identities = 19/40 (47%), Positives = 27/40 (67%)
 Frame = +1

Query: 676 QCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLA 795
           +CNW+R ++E P   + N  ++ +IL RL  ST FENFLA
Sbjct: 218 KCNWLRDKIETPTPRQYNQQRREVILDRLIWSTQFENFLA 257


>UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5;
           Viridiplantae|Rep: OSIGBa0096P03.7 protein - Oryza
           sativa (Rice)
          Length = 1016

 Score = 59.3 bits (137), Expect(2) = 2e-17
 Identities = 45/125 (36%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
 Frame = +3

Query: 312 SAGSP-INEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFAN 488
           +A SP I+ + I + + +  ++R+YQ  GHL A+LDPL +         D      AF  
Sbjct: 98  AATSPGISGQTIQESMRLLLLVRAYQVSGHLKAKLDPLALEERPIPDVLD-----PAFYG 152

Query: 489 EAVIRQHVRFDEADMDRVFKLP---STTFIGEKEKALPLREILNRLEQAYCNNIGIEFMF 659
                    F EAD+DR F L       F+ E      LR +L RLEQAYC  IG E+M 
Sbjct: 153 ---------FSEADLDREFFLGVWRMAGFLSENRPVQTLRSVLERLEQAYCGTIGYEYMH 203

Query: 660 INSLE 674
           I   E
Sbjct: 204 IPDRE 208



 Score = 53.2 bits (122), Expect(2) = 2e-17
 Identities = 26/56 (46%), Positives = 33/56 (58%)
 Frame = +3

Query: 24  KPQTAAVSVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRN 191
           +PQ  A  V    +  S   + FL+G+SS Y+E +  AW ADP SV  SWD FFRN
Sbjct: 39  RPQRFATPV-PRAVPLSRLTDSFLDGTSSVYLEELQRAWEADPTSVDESWDNFFRN 93



 Score = 44.4 bits (100), Expect = 0.004
 Identities = 18/42 (42%), Positives = 31/42 (73%)
 Frame = +1

Query: 673 KQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAK 798
           ++CNW+R R+E  N  + + D+++++L RL  ST FE+FLA+
Sbjct: 208 EKCNWLRDRIETVNAREYSYDRRQVMLDRLMWSTQFESFLAQ 249


>UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 component,
           mitochondrial, putative; n=9; Plasmodium|Rep:
           2-oxoglutarate dehydrogenase E1 component,
           mitochondrial, putative - Plasmodium vivax
          Length = 1059

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 61/201 (30%), Positives = 99/201 (49%), Gaps = 12/201 (5%)
 Frame = +3

Query: 96  NGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQP-GAAYTPPPNLAPYNKNEVPL 272
           N S +AY+E  Y  W  D NS+H SWD +F      A P G+A   PP +    +    +
Sbjct: 34  NPSMAAYIEGAYRMWRQDRNSLHKSWDVYFAEMAEEAGPLGSA---PPRVLSTREVRSRM 90

Query: 273 TSLVPSSGGMPSISAGSPINEKIID--------DHLAVQAIIRSYQSRGHLVAQLDPLGI 428
            + VP +    ++   + +N++++D        D   +  +IR YQ +GHL A ++PL +
Sbjct: 91  GASVPQNRSSSNLRI-TYVNKEMLDKGRMGNIYDIARIVQLIRWYQKKGHLYANINPLPL 149

Query: 429 STGDPVSSA--DWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTT-FIGEKEKALPLR 599
               P SS   +      ++++    +     D+ D +  F LPS T F   K++   LR
Sbjct: 150 PNVPPYSSVVNERDKNKMSYSDFGFTQ-----DDLDAEFEFDLPSITGFSSNKKETSTLR 204

Query: 600 EILNRLEQAYCNNIGIEFMFI 662
            +++RLEQ YC  IG E+M I
Sbjct: 205 SLIDRLEQTYCGTIGFEYMHI 225


>UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergillus
           oryzae|Rep: RIB40 genomic DNA, SC005 - Aspergillus
           oryzae
          Length = 453

 Score = 75.4 bits (177), Expect = 2e-12
 Identities = 59/187 (31%), Positives = 88/187 (47%), Gaps = 4/187 (2%)
 Frame = +3

Query: 126 MYNAWLADPNSVHASWDAFFRNATNGAQP-GAAYTPPPNLAPYNKNEVPLTSLVPSSGGM 302
           MY++W  DP+SVH SW A+F N  NG  P   A+  PP L   +      TS+ PSS   
Sbjct: 2   MYSSWKNDPSSVHLSWQAYFHNVENGHIPMDQAFMSPPGLVTASTR----TSIAPSSR-- 55

Query: 303 PSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAF 482
                 S + +      L V  +I++YQ  GH  A  DPLG++    +            
Sbjct: 56  ---EDSSTVKQ------LKVIQLIQAYQRWGHEHASTDPLGMANEGKI------------ 94

Query: 483 ANEAVIRQHVRFDEADMDRVFKLPSTT---FIGEKEKALPLREILNRLEQAYCNNIGIEF 653
             + +   H    E D+D V  + + +   F  EK K  PL E++   E+ YC+ +GIE+
Sbjct: 95  CRKELQLSHYGLSEQDLDLVLTVGTGSVQDFTSEKPK--PLWEVIAACEKTYCSTMGIEY 152

Query: 654 MFINSLE 674
           M I++ E
Sbjct: 153 MHISNQE 159



 Score = 34.7 bits (76), Expect = 3.0
 Identities = 16/45 (35%), Positives = 26/45 (57%)
 Frame = +1

Query: 673 KQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKNGP 807
           +Q +WIR R+E     +   ++KR +L  L R+T +E F+A   P
Sbjct: 159 EQVDWIRARIEGAQRHRFTDEEKRRMLHGLVRATSWEKFVATKFP 203


>UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=149; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
           component - Azotobacter vinelandii
          Length = 943

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 60/190 (31%), Positives = 93/190 (48%)
 Frame = +3

Query: 93  LNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVPL 272
           L+G ++AYVE +Y  +L DPN+V   W  +F      A+ G + T  P+ AP     V L
Sbjct: 15  LSGGNAAYVEELYELYLHDPNAVPEEWRTYFEKLP--AEAGTS-TDVPH-APVRDQFVLL 70

Query: 273 TSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSS 452
                 +  + + S  +   +K ++    V  +I++Y++RGH  +QLDPLG+        
Sbjct: 71  AKNQRRAQPVATSSVSTEHEKKQVE----VLRLIQAYRTRGHQASQLDPLGL-------- 118

Query: 453 ADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYC 632
             W    R   ++  I  H     AD+D  F+     +IG++E  L  REIL  L++ YC
Sbjct: 119 --WQ---RTAPSDLSIT-HYGLTNADLDTPFRT-GELYIGKEEATL--REILQALQETYC 169

Query: 633 NNIGIEFMFI 662
             IG EF  I
Sbjct: 170 RTIGAEFTHI 179


>UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, whole
           genome shotgun sequence; n=4; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_5,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 1002

 Score = 74.5 bits (175), Expect = 3e-12
 Identities = 57/205 (27%), Positives = 95/205 (46%), Gaps = 10/205 (4%)
 Frame = +3

Query: 90  FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVP 269
           FL   ++ +++ + + W  DPNSV A+WDA+FR      +    +TP P        +  
Sbjct: 24  FLGAQNAEFLDNLLDKWSQDPNSVPATWDAYFRQVCESNK--FDFTPEPQKGQTISFQAD 81

Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449
           +   + S      +S       K++ DH  V+ +I  Y+ RGH  + +DPL +     + 
Sbjct: 82  VLLHIISK----QVSGV----RKLLSDHFRVRLLINKYRHRGHEKSMVDPLDLEHIQQI- 132

Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIG-EKEK---------ALPLR 599
                G ++ +  +   R++  F E D+DR F +      G  KEK          + LR
Sbjct: 133 -----GKVKGYT-KLDYREY--FAEEDLDREFYIHDEVSSGISKEKQCNDLINYVVMKLR 184

Query: 600 EILNRLEQAYCNNIGIEFMFINSLE 674
           +++N LE+AYC  I  E+M I S E
Sbjct: 185 DLINYLEKAYCGKISYEYMHIQSTE 209


>UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=2; Proteobacteria|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Nitrosococcus oceani
           (strain ATCC 19707 / NCIMB 11848)
          Length = 940

 Score = 70.1 bits (164), Expect = 6e-11
 Identities = 59/202 (29%), Positives = 90/202 (44%), Gaps = 2/202 (0%)
 Frame = +3

Query: 63  LKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNL 242
           +K   +  P LN ++++Y+E +Y  +L DPN+V A W  +F+    G         P   
Sbjct: 5   VKKQASPSP-LNAANASYLEALYEKFLKDPNTVPAHWRIWFKRLQAGV--------PEQA 55

Query: 243 APYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPL 422
           AP      P  ++ PS+   PS      +  +  +  +AV  +I +Y+ RGH  A +DPL
Sbjct: 56  APEFPARSPGPAVQPSA---PSAVMTEGLTAEAAEKQIAVLQLINAYRFRGHQKANIDPL 112

Query: 423 GISTGDPVSSAD--WHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPL 596
            I     VS  D  +HG                  E DM +VF   S   I +     PL
Sbjct: 113 RIYDRPVVSDLDPVFHG----------------LTEEDMGKVFSTGSLIGIDQ----APL 152

Query: 597 REILNRLEQAYCNNIGIEFMFI 662
            EI   +++ YC+ IG E+M I
Sbjct: 153 EEIFALIKKIYCHTIGAEYMHI 174


>UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
           E1 component - Haemophilus influenzae
          Length = 935

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 58/210 (27%), Positives = 94/210 (44%), Gaps = 4/210 (1%)
 Frame = +3

Query: 57  NRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPP 236
           N+      A   L G++ +Y+E +Y ++L+DP SV  SW   F +          +TP  
Sbjct: 4   NKAFDDWLASTALGGANQSYIEELYESYLSDPQSVEESWRKTFDSLPKTTALEQPHTPVR 63

Query: 237 N----LAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLV 404
           +    LA  N NE  +T + P++G             K++     V   I +Y+ RGHL 
Sbjct: 64  DYFRRLARENHNEA-VTVIDPAAGA------------KLVK----VLQFINAYRFRGHLE 106

Query: 405 AQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEK 584
           A LDPL           +++    +F  E   R H  F E D++  F +    +   K  
Sbjct: 107 ANLDPL-----------NYYRWKVSFVPELDYRHH-GFTEQDLNETFNINHYVY---KRD 151

Query: 585 ALPLREILNRLEQAYCNNIGIEFMFINSLE 674
            + L E+   L++ YC +IG+EFM +  +E
Sbjct: 152 TIKLGELAQMLKETYCGSIGLEFMHVQDME 181


>UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17;
           Bacteria|Rep: Oxoglutarate dehydrogenase - Xylella
           fastidiosa
          Length = 967

 Score = 66.9 bits (156), Expect = 6e-10
 Identities = 64/214 (29%), Positives = 98/214 (45%)
 Frame = +3

Query: 42  VSVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAA 221
           +S+  N +K  T + P L G ++AY+E +Y  +L  PNSV   W A+F +   G   G  
Sbjct: 23  LSIVDNLIKQFTQSSP-LAGGNAAYIEDLYEQYLVSPNSVDPKWKAYF-DGFKGRDAGD- 79

Query: 222 YTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHL 401
                   P++     +T     S    S    S   E+ I        +I +Y+SRGHL
Sbjct: 80  -------IPHSAVIAHITDTAKQSVKAKSRQDASDERERNIG------RLITAYRSRGHL 126

Query: 402 VAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKE 581
            A++DPLG++   P S+            +  +  H    +AD+D  F   ST  IG + 
Sbjct: 127 SARIDPLGLT---PPSNPP----------DLDLPFH-HLSQADLDNEF---STGGIGGQP 169

Query: 582 KALPLREILNRLEQAYCNNIGIEFMFINSLETMQ 683
           + + LR +L  L+  Y + IG EFM I+  E  Q
Sbjct: 170 R-MKLRNLLAHLKATYTDTIGTEFMHISEFEQRQ 202


>UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=11; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
           E1 component - Coxiella burnetii
          Length = 934

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 57/192 (29%), Positives = 92/192 (47%)
 Frame = +3

Query: 90  FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVP 269
           +L  +++ Y+ET+Y  +L DP+SV+  W ++FR  TNGA      TP  + A   + E  
Sbjct: 14  YLADNNAGYIETLYENFLKDPHSVNEEWRSYFRTLTNGAS-----TPDISHATI-REEFR 67

Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449
             +  P S    +I+  +        +  AV  +I  Y+  GHL A+++PLG     PV 
Sbjct: 68  ELARKPRSISPTAITPAA--------EQAAVDLLIEGYRRFGHLNAKINPLG--DNRPVD 117

Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629
           S    G             H    E+D ++ F   +T  +  K KA  L+EI  RL + Y
Sbjct: 118 SRLELG-------------HYNLTESDFNKTF---ATYGLLNKPKA-TLKEIYTRLREIY 160

Query: 630 CNNIGIEFMFIN 665
           C +IG+++  I+
Sbjct: 161 CGSIGVQYSTIS 172


>UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=1; Orientia tsutsugamushi Boryong|Rep:
           2-oxoglutarate dehydrogenase, E1 component - Orientia
           tsutsugamushi (strain Boryong) (Rickettsia
           tsutsugamushi)
          Length = 963

 Score = 63.3 bits (147), Expect = 7e-09
 Identities = 54/195 (27%), Positives = 85/195 (43%), Gaps = 5/195 (2%)
 Frame = +3

Query: 84  EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRN-ATNGAQPGAAYTPPPNLAPYNKN 260
           + FL   ++ Y+E ++  +L DP S+ +SW  FF+    N  +     T    L  YN  
Sbjct: 9   QSFLFRQNAEYIEHLHQKYLKDPASIDSSWITFFQEYCRNECEHPIVVTNKSEL-NYNNF 67

Query: 261 EVPLTSLVPSSGGMPSIS---AGSPINEKIID-DHLAVQAIIRSYQSRGHLVAQLDPLGI 428
              L S       + S +        N+++I+   L +Q +I  Y+S GHL A+LDPL +
Sbjct: 68  RFKLASNNGVGSAISSTTNKLDDLDSNKQLINLKQLQIQQLIEVYRSNGHLCAKLDPLNL 127

Query: 429 STGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREIL 608
                   A  H  +  F             E D+D+ F     T      +   LR ++
Sbjct: 128 QEQKTKEQA--HLSLNYFG----------LSEFDLDKNFHF---TLCNNFAQVSNLRTLI 172

Query: 609 NRLEQAYCNNIGIEF 653
           ++LEQ YC NI +EF
Sbjct: 173 SQLEQIYCGNIAVEF 187


>UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=12; root|Rep: 2-oxoglutarate dehydrogenase,
           E1 component - Polaromonas sp. (strain JS666 / ATCC
           BAA-500)
          Length = 963

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 52/191 (27%), Positives = 83/191 (43%), Gaps = 1/191 (0%)
 Frame = +3

Query: 90  FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATN-GAQPGAAYTPPPNLAPYNKNEV 266
           +L G ++ YVE MY  +LA+P SV  +W  +F    +  A  G+     P+L   N    
Sbjct: 20  YLFGGNAPYVEEMYENYLANPGSVPDNWRDYFDALQHVPAVDGSNAKDVPHLPVVN---- 75

Query: 267 PLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPV 446
                  +  G   +   S  + ++     A Q +I +Y++ G   A LDPL  +  D +
Sbjct: 76  --AFAERAKQGQTKVGEASGADSEMGRKRTATQQLIAAYRNVGARWADLDPLKRAERDKI 133

Query: 447 SSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQA 626
              +                   F +AD + VF   S TF G+    + LRE++N L + 
Sbjct: 134 PELE--------------PSFYGFTDADQETVFNT-SNTFFGKD--TMSLRELINALRET 176

Query: 627 YCNNIGIEFMF 659
           YC  IG E+M+
Sbjct: 177 YCGTIGAEYMY 187


>UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1;
           Opitutaceae bacterium TAV2|Rep: Oxoglutarate
           dehydrogenase - Opitutaceae bacterium TAV2
          Length = 384

 Score = 44.0 bits (99), Expect(2) = 3e-08
 Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 2/124 (1%)
 Frame = +3

Query: 297 GMPSISAGSPINEKIIDDHLAVQA--IIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGG 470
           G P I A    + KIID +   Q    I +++S GHL A LDPLG +       A     
Sbjct: 45  GSP-IGAAPASDIKIIDSYKQAQVGRFINAHRSHGHLEAHLDPLGDAPPPHPKLA----- 98

Query: 471 MRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIE 650
           + +F             + D+D  F L  T F G  +  + LR+I+  ++  YC+N+G+E
Sbjct: 99  LASFG----------LTDDDLDEAFTL--TNFKGGGQ--MRLRDIVEAVKDTYCSNVGVE 144

Query: 651 FMFI 662
           +M +
Sbjct: 145 YMHV 148



 Score = 37.1 bits (82), Expect(2) = 3e-08
 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 3/43 (6%)
 Frame = +3

Query: 102 SSSAYVETMYNAWLADPNSVHASWDAFFRN---ATNGAQPGAA 221
           ++SA +E  Y+ WL +P+SV  +W AFF+     T G+  GAA
Sbjct: 9   ANSAILEQTYSQWLDNPDSVDPTWRAFFQGFTLGTTGSPIGAA 51


>UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=2; Cystobacterineae|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Myxococcus xanthus (strain
           DK 1622)
          Length = 963

 Score = 60.1 bits (139), Expect = 7e-08
 Identities = 52/197 (26%), Positives = 89/197 (45%), Gaps = 6/197 (3%)
 Frame = +3

Query: 84  EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQP-GAAYTPPPNLAPY--- 251
           + FL+G++  ++E +Y  +L DP SV ASW   F  +    +P  +     P  AP    
Sbjct: 6   DTFLSGANIDFIEGLYARYLEDPASVDASWREVFDRSNGAGRPIFSTRLLEPVAAPAAAK 65

Query: 252 --NKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLG 425
              K   P   + P+    P  + G  + +  I     V  +I +++ RGHL A+LDPL 
Sbjct: 66  GGGKGAAPKAQVAPAPQPAPVAAPGQSVQD--ISLQARVDHVIFAFRLRGHLRAKLDPL- 122

Query: 426 ISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREI 605
              G P  +        A   +  +     F +A+  ++  + +    GE+   + L E+
Sbjct: 123 ---GRPRPAL-------AHVADVALVDDSHFTDAEAQQL--VETNGVFGEQR--VRLTEL 168

Query: 606 LNRLEQAYCNNIGIEFM 656
           L RL + Y + IG+E+M
Sbjct: 169 LARLRRTYTDTIGVEYM 185


>UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1
           component family protein; n=1; Tetrahymena thermophila
           SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component
           family protein - Tetrahymena thermophila SB210
          Length = 1054

 Score = 59.7 bits (138), Expect = 9e-08
 Identities = 34/113 (30%), Positives = 57/113 (50%)
 Frame = +3

Query: 84  EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNE 263
           + FL G ++ +VE ++  W  DP SV  SW+ +F+N   G +P  A++ PP+        
Sbjct: 36  DSFLAGCNAEFVEGLFERWAEDPTSVGPSWNNYFKNLVRGVEPEYAFSLPPS-------- 87

Query: 264 VPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPL 422
             LT  +          A     + I+ D+L  + ++ +Y+ RGH +A LDPL
Sbjct: 88  -DLTKAIH--------MAPDHAMKFIVSDNLKARLLVDAYRIRGHEIADLDPL 131


>UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=16; cellular organisms|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Robiginitalea biformata
           HTCC2501
          Length = 940

 Score = 58.8 bits (136), Expect = 2e-07
 Identities = 54/198 (27%), Positives = 89/198 (44%)
 Frame = +3

Query: 90  FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVP 269
           FLN + +A+   +Y+ +L  P+SV  SW AFF+    G +           A        
Sbjct: 6   FLNAAHTAFFSDLYDRYLTHPDSVEPSWRAFFQGFDFGMESALEEIGIDAEA-------- 57

Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449
              +V ++GG     A  P++ K       V  +I  Y+SRGHL  Q +P+         
Sbjct: 58  --GVVRTAGGD---EAAMPLSLK---KEFQVVRLIDGYRSRGHLFTQTNPVR-------- 101

Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629
                   R +     I ++   +E+D+++VF       IG       LREI++ L + Y
Sbjct: 102 ------ERRTYTPSLEI-ENFGLEESDLEKVFSAGDIIGIGPST----LREIIDHLTRIY 150

Query: 630 CNNIGIEFMFINSLETMQ 683
           C+ IG+E+M+I S E ++
Sbjct: 151 CDAIGVEYMYIRSPERVE 168


>UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 component,
           putative; n=6; Trypanosomatidae|Rep: 2-oxoglutarate
           dehydrogenase E1 component, putative - Leishmania major
          Length = 979

 Score = 57.6 bits (133), Expect = 4e-07
 Identities = 49/197 (24%), Positives = 84/197 (42%), Gaps = 4/197 (2%)
 Frame = +3

Query: 84  EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNE 263
           + FL+GSS+ Y++ +Y  W  DP SV ASW   F  +              +L  YN   
Sbjct: 20  DSFLSGSSAMYMDGLYQQWKKDPASVDASWAELFSRS--------------DLGNYNHAL 65

Query: 264 VPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDP 443
           +     V     +P+ S+   + ++ + D   +  +I +++ RGHL+AQ DPL     D 
Sbjct: 66  LDTPICV-----LPAKSSDEAVVKQSLADCGRLIRMIHTFEDRGHLMAQTDPLNYVDTDV 120

Query: 444 VSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIG----EKEKALPLREILN 611
                     R      +   +  F + D+DRV ++     +G         L +R++  
Sbjct: 121 TERTP---SRRYKEMVRLDLAYFGFSDKDLDRVVRVGFQNQMGGIYDTSSPQLTIRQLHE 177

Query: 612 RLEQAYCNNIGIEFMFI 662
            L + YC  IG E + +
Sbjct: 178 LLTERYCGRIGFELVHL 194


>UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=4;
           Bacteria|Rep: Alpha-ketoglutarate dehydrogenase E1 -
           Rhodopirellula baltica
          Length = 969

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 61/214 (28%), Positives = 88/214 (41%), Gaps = 22/214 (10%)
 Frame = +3

Query: 93  LNGSSSAYVETMYNAWLADPNSVHASWDAFFRN------ATNGAQPGAAYTPPPNLAPYN 254
           +N  S  Y++ +Y  ++ DP+SV  +W  +F        A   A P A+ T     A  N
Sbjct: 14  MNSYSLDYIDDLYVQYVRDPSSVSETWRQYFEQFLVGAGARTNAAPAASQTASQGDASAN 73

Query: 255 KNEVPLTSLV--------PSSGGMPSISAGSPINEKIIDDHL-------AVQAIIRSYQS 389
                  S+V        P S    S   GS   ++ +D  L        V  ++R Y+ 
Sbjct: 74  GKTSGARSVVAPAFASGQPGSAEDTSERPGST-GDQNVDQALWLARIQDRVDQLVREYRV 132

Query: 390 RGHLVAQLDPLGISTGD-PVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTF 566
           RGHLVA LDPLG+     P  S   HG                  + D+ R    P  + 
Sbjct: 133 RGHLVATLDPLGLFEHTCPELSPRSHG----------------LSKQDLAR----PFDSS 172

Query: 567 IGEKEKALPLREILNRLEQAYCNNIGIEFMFINS 668
           I E      L  ILN+L+  YC +IG +FM I++
Sbjct: 173 ILENVSGSTLDVILNKLQSTYCRSIGAQFMHIDN 206


>UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E1
           component; n=7; Bacteria|Rep: 2-oxoglutarate
           dehydrogenase complex, E1 component - Azoarcus sp.
           (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 942

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 52/192 (27%), Positives = 87/192 (45%)
 Frame = +3

Query: 90  FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVP 269
           +L G+++ ++E +Y  +LADP +V  +W  +F +A   AQ GAA         +      
Sbjct: 10  YLFGANAPFIEELYENYLADPAAVPEAWRGYF-DALQ-AQAGAAVRD----VAHGPVIAA 63

Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449
            T L    G + +++AG     ++     +   +I +Y+  G+  A LDPL  +    ++
Sbjct: 64  FTELA-KRGPVRTVTAGGDDRRQV-----STLQLINAYRFLGNRWANLDPLKRTERPQLA 117

Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629
             +                   F EAD+++ F + S  F G       LREIL  L Q Y
Sbjct: 118 ELE--------------PSFYGFTEADLNQSFNVGS--FHGFSADHATLREILEALRQTY 161

Query: 630 CNNIGIEFMFIN 665
           C +IG E+M I+
Sbjct: 162 CGSIGSEYMHIS 173


>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
           component - Brucella melitensis
          Length = 1004

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 68/227 (29%), Positives = 103/227 (45%), Gaps = 24/227 (10%)
 Frame = +3

Query: 57  NRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFF-----------RNA--- 194
           +R     A   FL G ++ Y+E +Y  +  DPNSV   W  FF           +NA   
Sbjct: 9   DRANDVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGP 68

Query: 195 --TNGAQPGAAYTPPPNLAPYNKNEVP--LTSLVPSSG--GMPSISAGSPINEKIIDDHL 356
             T    P AA     +    N  EV   +T  +      G    +AG+P+  + I    
Sbjct: 69  SWTRKNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAA 128

Query: 357 --AVQAI--IRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDE 524
             +V+AI  IR+Y+ RGHL A LDPLG++        D+        NE +  ++  F  
Sbjct: 129 RDSVRAIMMIRAYRMRGHLHANLDPLGLAE----KPNDY--------NE-LEPENYGFTP 175

Query: 525 ADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFIN 665
           AD +R  K+     +G +   +P  E+L+ L++ YC  IG+EFM I+
Sbjct: 176 ADYNR--KIFIDNVLGLEYATVP--EMLDILKRTYCGAIGVEFMHIS 218


>UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
           n=2; Anaeromyxobacter|Rep: 2-oxoglutarate dehydrogenase,
           E1 subunit - Anaeromyxobacter sp. Fw109-5
          Length = 940

 Score = 50.4 bits (115), Expect = 6e-05
 Identities = 51/196 (26%), Positives = 84/196 (42%)
 Frame = +3

Query: 87  PFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEV 266
           P  + S+ ++VE +Y  WLADP++V   W  +F +    A PG A  P    AP      
Sbjct: 11  PAPSASNLSFVEDLYYEWLADPSAVDERWRRYFESVP--ATPGTAKAPEA-FAPRR---- 63

Query: 267 PLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPV 446
           P   + P+ G   + SA +    K       V  ++ +Y+  GHL A LDPL ++     
Sbjct: 64  PDGGVAPAPGAALA-SADAAFQAK-------VDRLVTAYREYGHLRADLDPLALTRRAER 115

Query: 447 SSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQA 626
            S    G                  +A+++R    P     G  ++   LR ++ RLE+ 
Sbjct: 116 FSPATFG----------------LSDAELER----PCADPEGRGDRT--LRGLVARLEET 153

Query: 627 YCNNIGIEFMFINSLE 674
           YC  +G+E   ++  +
Sbjct: 154 YCRTLGVELAHMHDAD 169


>UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase
           (Succinyl-transferring), E1 component; n=4;
           Bacteroidetes|Rep: Oxoglutarate dehydrogenase
           (Succinyl-transferring), E1 component - Cytophaga
           hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 946

 Score = 49.6 bits (113), Expect = 1e-04
 Identities = 52/208 (25%), Positives = 89/208 (42%)
 Frame = +3

Query: 57  NRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPP 236
           NR KS+     +++ +  +YV+ MY ++  DP+SV  +W  FF       Q         
Sbjct: 5   NRKKSTMDNYSYVSNAEISYVDEMYQSYRKDPSSVDETWQKFFEGYNFSLQKYG------ 58

Query: 237 NLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLD 416
                N      ++  PS  G+ ++ A SP    + +  + V  +I +Y+SRGHL ++ +
Sbjct: 59  EKGATNGG----SAEAPSGNGVAAV-ASSPAT-TVSEKEVRVHYLIHAYRSRGHLRSKTN 112

Query: 417 PLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPL 596
           P+                 R      +        +AD+D VF+  +   IG    A  L
Sbjct: 113 PV---------------RERKDRKPLLELTDFGLTDADLDVVFEAGNEIGIG----AASL 153

Query: 597 REILNRLEQAYCNNIGIEFMFINSLETM 680
           R+I+  L+  Y   IG E+M+I   E +
Sbjct: 154 RKIVETLKFIYEGAIGFEYMYIRKPEKL 181


>UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=4; Leptospira|Rep: 2-oxoglutarate dehydrogenase E1
           component - Leptospira interrogans
          Length = 920

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 57/196 (29%), Positives = 85/196 (43%), Gaps = 2/196 (1%)
 Frame = +3

Query: 93  LNGSSSAYVETMYNAWLADPNSVHASWDAFFRNA-TNGAQPGAAYTPPPNLAPYNKNEVP 269
           L G + A +E +YN +  +P ++   W +FF+   TNG   G+ YT        N     
Sbjct: 9   LYGENGALLEELYNQYKLNPETLDKEWKSFFQEVDTNGLANGSGYTNG------NGKSAV 62

Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449
            TS   +     SI     IN            ++ +Y+ +GHL A+LDPLGI   +   
Sbjct: 63  ATSFTDAQAA--SIREMGIIN------------LLNAYRRQGHLAAKLDPLGIQKPN--- 105

Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629
                   R F +    + H     AD+D V  + S T +G     + L EI++  E+ Y
Sbjct: 106 --------RTFIDS---KLH-NISPADIDTV--VDSET-LGR----VKLAEIVDLYEKVY 146

Query: 630 CNNIGIE-FMFINSLE 674
           CN IG E F  +N  E
Sbjct: 147 CNTIGAEHFYLVNDEE 162


>UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Blochmannia floridanus
          Length = 970

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 46/198 (23%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
 Frame = +3

Query: 90  FLNGSSSAYVETMYNAWLADPNSVHASWDAFFR-------NATNGAQPGAAYTPPPNLAP 248
           FL  ++ +Y++ +Y  +L +P+S+  SW   F+       N          ++  P L+ 
Sbjct: 14  FLTKNNQSYIDQIYEFFLKNPHSIDISWINIFKEWDIEEKNQNQSIINKQLHSTSPLLSE 73

Query: 249 YNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGI 428
           Y+K +    S + +              EK I+    +Q +I S++  GH  + LDPLG+
Sbjct: 74  YDKQDNSYKSYISTDID----------KEKTINISKILQ-LIHSFRKYGHQYSILDPLGL 122

Query: 429 STGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREIL 608
           +             +    N  +  ++ +F + D+ + F    T  +G  +  + L  I 
Sbjct: 123 T-------------INTVKNSFLELKYYKFLDKDVLQQF---DTNLLGMNKGIITLNSIY 166

Query: 609 NRLEQAYCNNIGIEFMFI 662
             L++ YC  IGIE+M I
Sbjct: 167 KFLKKTYCGTIGIEYMHI 184


>UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
           Plesiocystis pacifica SIR-1|Rep: Alpha-ketoglutarate
           decarboxylase - Plesiocystis pacifica SIR-1
          Length = 927

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 52/191 (27%), Positives = 72/191 (37%)
 Frame = +3

Query: 81  AEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKN 260
           AE  L+  + A++E +Y A+ ADPNSV   W          A                  
Sbjct: 3   AEAALSVHNLAFLEALYEAYEADPNSVDPQWIPLLEEGRASA------------------ 44

Query: 261 EVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGD 440
               +S   SS  + S   GS   E  +     V  +I +Y+  GH+ A +DPLG     
Sbjct: 45  ----SSSSESSSRLHSAEPGSSAEEITLQTQ--VDNLIEAYRLHGHIGADIDPLGRPRST 98

Query: 441 PVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLE 620
             +  D                H    E  MDR F     T      KA  LREI+ RL 
Sbjct: 99  DATELD--------------PAHYGLGEQHMDREFGTAGLT----PHKA-SLREIIERLR 139

Query: 621 QAYCNNIGIEF 653
             YC ++G+E+
Sbjct: 140 NTYCRHVGVEY 150


>UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=1;
           Blastopirellula marina DSM 3645|Rep: Alpha-ketoglutarate
           dehydrogenase E1 - Blastopirellula marina DSM 3645
          Length = 929

 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 50/189 (26%), Positives = 79/189 (41%), Gaps = 4/189 (2%)
 Frame = +3

Query: 111 AYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAP--YNKNEVPLTSLV 284
           AY   + +A+  DPNSV   W  +F           A+T   NLAP     +    T   
Sbjct: 2   AYAAELLDAYREDPNSVPDDWREWFGKLPQANGDAEAFT---NLAPPITTSSMFNPTGAP 58

Query: 285 PSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGD-PVSSADW 461
            +  G  + SAG             V  +I ++++ GHL ++LDPLG++T   P  S D 
Sbjct: 59  VAVNGDHAASAGDAAVGADALLQFCVDRMITAFRAYGHLHSRLDPLGLTTTPAPPLSPD- 117

Query: 462 HGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKAL-PLREILNRLEQAYCNN 638
                               E+D+DR     S     + E  L  +RE+  R+++ YC +
Sbjct: 118 ---------------QFNIKESDLDR-----SVYVDRDGETILTTVRELFERMQRVYCGD 157

Query: 639 IGIEFMFIN 665
           +GI+   I+
Sbjct: 158 VGIQLQHID 166


>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=3; Bacteria|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Salinibacter ruber (strain
           DSM 13855)
          Length = 1243

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 41/138 (29%), Positives = 65/138 (47%), Gaps = 1/138 (0%)
 Frame = +3

Query: 264 VPLTSLVPSSGGMPSISAGSPINE-KIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGD 440
           VP      ++   P +    P +E  + +   AV  +IR+Y+ RGHL A ++PLG     
Sbjct: 354 VPYQPFRMATDSTPQLGRSRPQDELDMTEKQAAVLQLIRAYRVRGHLQADINPLGY---- 409

Query: 441 PVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLE 620
                +W        +E +          D+DR F    T  +G ++K LPLREIL+ L 
Sbjct: 410 -----EWQ------YHEELDPATYGLTVWDLDREF---ITGGLGGEDK-LPLREILSILR 454

Query: 621 QAYCNNIGIEFMFINSLE 674
           ++Y + +G  FM I+  E
Sbjct: 455 KSYTSKVGTAFMHISDPE 472


>UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 component,
           putative; n=2; Theileria|Rep: 2-oxoglutarate
           dehydrogenase e1 component, putative - Theileria parva
          Length = 1030

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 4/197 (2%)
 Frame = +3

Query: 96  NGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPP---NLA-PYNKNE 263
           +G S  Y+E +Y  +  +P  +  SW  +F    +  + G  YT P     L   YN   
Sbjct: 19  HGESLNYLEYLYYVYRTNPEHLQPSWQNYF----SLLEQGKTYTLPQIDRKLGHKYNGFA 74

Query: 264 VPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDP 443
            PL     +S     ++  S  N  +  + L +  +  +Y++ GHLV+ LDPL +    P
Sbjct: 75  GPLAGNQTTSQATELLAKVS--NGVVGLEVLKLNELASAYRTFGHLVSNLDPLKLPKEVP 132

Query: 444 VSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQ 623
                +   +    ++  + ++  F++ D+ +  K+P+    G       + E+  +L++
Sbjct: 133 -----FFRNIDGIYDKLNVNKY--FNKDDLAK--KIPNLGIGGVFNMTGTVEELAEKLKE 183

Query: 624 AYCNNIGIEFMFINSLE 674
            YC NI  EF  I + E
Sbjct: 184 RYCGNISFEFGHIANSE 200


>UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=45; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
           component - Corynebacterium glutamicum (Brevibacterium
           flavum)
          Length = 1257

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
 Frame = +3

Query: 342 IDDHLAVQAIIRSYQSRGHLVAQLDPLG-ISTGDPVSSADWHGGMRAFANEAVIRQHVRF 518
           +D +  V  +I +Y+SRGHL+A  +PL  +  G PV     H  +    +   I      
Sbjct: 402 VDKNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMPVPD---HRDLDIETHNLTI------ 452

Query: 519 DEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFI 662
              D+DR F +      G KE  + LRE+L+RL  AY   +G E+  I
Sbjct: 453 --WDLDRTFNVGG---FGGKE-TMTLREVLSRLRAAYTLKVGSEYTHI 494


>UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=8; Deltaproteobacteria|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Geobacter sulfurreducens
          Length = 894

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 20/52 (38%), Positives = 28/52 (53%)
 Frame = +3

Query: 90  FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLA 245
           F  G+   ++E+++ +W ADP SV A W AFF     G    +A  P P LA
Sbjct: 3   FAAGADPEFIESLFQSWQADPASVSAEWRAFFTGYELGRGEPSAECPTPELA 54



 Score = 43.2 bits (97), Expect = 0.008
 Identities = 37/122 (30%), Positives = 58/122 (47%)
 Frame = +3

Query: 297 GMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMR 476
           G PS    +P   ++     AV ++I  Y+  GHL+A  DPL      P           
Sbjct: 42  GEPSAECPTP---ELAAKQSAVDSLIYRYRDLGHLLACTDPLS-----PCK--------- 84

Query: 477 AFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFM 656
              +  +  +    D++D+DR F+  +  F+  K +A  LREIL  L + YC ++G+EFM
Sbjct: 85  -LEHPLLALEQYDLDQSDLDRTFR--ARRFL--KSEAT-LREILATLRETYCRSVGVEFM 138

Query: 657 FI 662
            I
Sbjct: 139 HI 140


>UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=15; Bacteria|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Deinococcus radiodurans
          Length = 956

 Score = 44.4 bits (100), Expect = 0.004
 Identities = 47/195 (24%), Positives = 89/195 (45%), Gaps = 3/195 (1%)
 Frame = +3

Query: 99  GSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVPLTS 278
           G ++A++E +Y ++L DP+SV A W ++F     GAQ               ++  P+T 
Sbjct: 15  GGNAAFIEGLYESYLQDPSSVGAEWRSYFDGLRGGAQERVHSEVQQRFYELGQHRGPVT- 73

Query: 279 LVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPL---GISTGDPVS 449
            V  +GG    ++G+           A  A++ +Y+  GH+ A+ +PL   G+ T  P  
Sbjct: 74  -VQVTGG----ASGA---------QQAAGALVTAYRVYGHISARNNPLKLRGVPT-VPEL 118

Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629
           + +++G                  EAD+    ++  + F G       LR+++ +L+  Y
Sbjct: 119 TPEFYG----------------LSEADLSE--QVQDSPFSG------TLRDVIAQLQDTY 154

Query: 630 CNNIGIEFMFINSLE 674
           C  IG E+ ++ + E
Sbjct: 155 CGAIGFEYNYLPANE 169


>UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Alpha-ketoglutarate
           decarboxylase - Lentisphaera araneosa HTCC2155
          Length = 913

 Score = 44.4 bits (100), Expect = 0.004
 Identities = 27/114 (23%), Positives = 55/114 (48%)
 Frame = +3

Query: 342 IDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFD 521
           ++  + +  +I +Y+SRGHL+++ +P+                 R      +   +   D
Sbjct: 56  VEKEVKIMKLINAYRSRGHLISKTNPIR---------------PRRLHQADLTLDYFGLD 100

Query: 522 EADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLETMQ 683
           EAD++  F +     +G  +    L++I++ LE  YC++IG+E+ +  S E  Q
Sbjct: 101 EADLEEEFDVGHEIRLGRAK----LKDIISHLEDTYCSSIGVEYRYSQSSEMRQ 150



 Score = 35.9 bits (79), Expect = 1.3
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = +3

Query: 96  NGSSSAYVETMYNAWLADPNSVHASWDAFFR 188
           + ++ AY+E M   +  DPNSV ASW  FF+
Sbjct: 8   DNANPAYIEMMLQKFKTDPNSVDASWQQFFQ 38


>UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
           n=2; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
           subunit - Solibacter usitatus (strain Ellin6076)
          Length = 1220

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 3/123 (2%)
 Frame = +3

Query: 303 PSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAF 482
           P++   S      I     +  +I +Y+ RGHL+A LDPLG       S    H  +   
Sbjct: 329 PTLPGVSAARYAEIAKEAGIIQMINAYRVRGHLIADLDPLG-------SEPSLHAELDPE 381

Query: 483 ANEAVIRQHVRFDEADMDRVFKLPST-TFIGE-KEKALP-LREILNRLEQAYCNNIGIEF 653
                I         D+DR F   S    IGE   K+L  LREIL  L Q YC  IG E+
Sbjct: 382 TYGLTIW--------DLDREFLTGSLGEAIGEGAPKSLATLREILETLRQTYCGKIGCEY 433

Query: 654 MFI 662
           M I
Sbjct: 434 MNI 436


>UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=11; Francisella tularensis|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Francisella tularensis
           subsp. tularensis (strain FSC 198)
          Length = 941

 Score = 41.5 bits (93), Expect = 0.026
 Identities = 29/110 (26%), Positives = 56/110 (50%)
 Frame = +3

Query: 345 DDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDE 524
           D  L  +A++++Y+S G+  A +DPLG++  +  S  +             +  H    E
Sbjct: 92  DIGLKAKALVKAYRSYGYKSANIDPLGLTRFERDSDLE-------------LAAH-GLSE 137

Query: 525 ADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLE 674
            D+ ++  L   T      KA+PL++++N+ +  Y +NIG E+ +I + E
Sbjct: 138 KDLTQLVNLGDFT----DNKAIPLQQVINKAKAIYESNIGYEYRYIGNKE 183


>UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 component
           , putative; n=1; Babesia bovis|Rep: 2-oxoglutarate
           dehydrogenase E1 component , putative - Babesia bovis
          Length = 891

 Score = 41.5 bits (93), Expect = 0.026
 Identities = 25/103 (24%), Positives = 48/103 (46%)
 Frame = +3

Query: 354 LAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADM 533
           L +  ++R+Y++ GH V+ LDPL +    P     +H  + +  +  +   H  +   D 
Sbjct: 22  LRLSELVRAYRTEGHCVSTLDPLDLPREPP-----FHRFIPSDVSTKLC--HTTYGLKDE 74

Query: 534 DRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFI 662
           D    LPS    G    +  + E ++ L + YC +  +EF+ +
Sbjct: 75  DLGRPLPSGLIPGHMGSSSTVAECIDNLRRTYCGDFAVEFIHL 117


>UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=5; Enterobacteriaceae|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Escherichia coli (strain
           UTI89 / UPEC)
          Length = 939

 Score = 40.7 bits (91), Expect = 0.045
 Identities = 31/123 (25%), Positives = 58/123 (47%)
 Frame = +3

Query: 306 SISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFA 485
           S+S  + ++   +    AV  +I +++++GHL A+LDPLG++   P        G    +
Sbjct: 75  SVSGDNNVSGATLKKQAAVIQLINAWRTQGHLRAKLDPLGLN--PPADVPSLQPGFWGLS 132

Query: 486 NEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFIN 665
            E ++++                S TF G     +PL+++LN LEQA+  +   E   + 
Sbjct: 133 EEDLLQEF---------------SVTF-GAHTTQMPLKQLLNLLEQAWAGSQAYELAHLE 176

Query: 666 SLE 674
           + E
Sbjct: 177 NRE 179


>UniRef50_A5XEI0 Cluster: Oxoglutarate (Alpha-ketoglutarate)
           dehydrogenase; n=4; Euteleostomi|Rep: Oxoglutarate
           (Alpha-ketoglutarate) dehydrogenase - Homo sapiens
           (Human)
          Length = 65

 Score = 39.1 bits (87), Expect = 0.14
 Identities = 16/24 (66%), Positives = 21/24 (87%)
 Frame = +3

Query: 360 VQAIIRSYQSRGHLVAQLDPLGIS 431
           VQ++IR+YQ RGH + +LDPLGIS
Sbjct: 1   VQSLIRAYQVRGHHIVKLDPLGIS 24


>UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 1304

 Score = 38.7 bits (86), Expect = 0.18
 Identities = 33/105 (31%), Positives = 47/105 (44%)
 Frame = +3

Query: 360 VQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDR 539
           +  +I +Y+SRGHL A  DPL                 R   +  +          D+DR
Sbjct: 440 IAELIHAYRSRGHLAADTDPLAY---------------RVRRHPDLDLSSYGLSVWDLDR 484

Query: 540 VFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLE 674
            F  P+  F G+ ++ L LR+IL RL   Y   +GIE+M I   E
Sbjct: 485 PF--PTGGF-GDSDQML-LRDILTRLHDTYTRTVGIEYMHIQDPE 525


>UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 component
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           2-oxoglutarate dehydrogenase, E1 component family
           protein - Tetrahymena thermophila SB210
          Length = 992

 Score = 37.9 bits (84), Expect = 0.32
 Identities = 14/27 (51%), Positives = 18/27 (66%)
 Frame = +3

Query: 105 SSAYVETMYNAWLADPNSVHASWDAFF 185
           S+ YVE M++ W  DPNSVH  W  +F
Sbjct: 37  SNLYVEQMFDQWSKDPNSVHEMWRDYF 63


>UniRef50_Q2JFB9 Cluster: Putative uncharacterized protein; n=1;
           Frankia sp. CcI3|Rep: Putative uncharacterized protein -
           Frankia sp. (strain CcI3)
          Length = 900

 Score = 36.7 bits (81), Expect = 0.73
 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 3/64 (4%)
 Frame = +3

Query: 144 ADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYN---KNEVPLTSLVPSSGGMPSIS 314
           ADP  V  +WD        G  PG + TPP    P      +  P+ S  P     P +S
Sbjct: 11  ADPFDVTTTWDGPAPGPAGGRPPGISVTPPAPAGPSTPAVSSAAPVASPAPPVPRGPRVS 70

Query: 315 AGSP 326
           AG P
Sbjct: 71  AGPP 74


>UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=17; Staphylococcus|Rep: 2-oxoglutarate dehydrogenase
           E1 component - Staphylococcus aureus
          Length = 932

 Score = 36.3 bits (80), Expect = 0.97
 Identities = 14/39 (35%), Positives = 24/39 (61%)
 Frame = +1

Query: 685 WIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKN 801
           W+++R+E P    +N ++KR +  +L    GFE +L KN
Sbjct: 164 WLKRRIETPYKVTLNNNEKRALFKQLAYVEGFEKYLHKN 202


>UniRef50_Q8UDS8 Cluster: Short chain dehydrogenase; n=1;
           Agrobacterium tumefaciens str. C58|Rep: Short chain
           dehydrogenase - Agrobacterium tumefaciens (strain C58 /
           ATCC 33970)
          Length = 249

 Score = 35.9 bits (79), Expect = 1.3
 Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 3/106 (2%)
 Frame = +3

Query: 171 WDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDD 350
           WD         A  GA Y  PP L     + V  +S V +S G+P +SA       ++  
Sbjct: 108 WDHVLNVNLTSAFLGARYQIPPMLKRGGGSIVFTSSFVGTSAGIPGMSAYGTAKAALMG- 166

Query: 351 HLAVQAIIRSYQSRGHLVAQLDPLGIST---GDPVSSADWHGGMRA 479
              V+ I   Y   G     L P G+ T   GDP +  +W  G+ A
Sbjct: 167 --LVKGITADYAINGIRANALLPGGVDTPAAGDP-AQKEWAAGLHA 209


>UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit,
           putative; n=7; Trypanosomatidae|Rep: 2-oxoglutarate
           dehydrogenase subunit, putative - Trypanosoma brucei
          Length = 1008

 Score = 35.5 bits (78), Expect = 1.7
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
 Frame = +3

Query: 354 LAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADM 533
           + +  ++ +Y+  GH  A+++PL        S  D     R   N  +   +  F + D+
Sbjct: 102 MGITWMVTAYERYGHHYAKVNPLR-------SEQDVESDRRDLLN--LHYSNFGFTDQDL 152

Query: 534 DRVFKLPS----TTFIGEKEKALPLREILNRLEQAYCNNIGIEFM 656
            +VF +          GE  K   L++I+ +L+  YC +IG EF+
Sbjct: 153 TKVFPVDIGGGLKEAFGENVKEATLQQIVEKLQMMYCGSIGFEFL 197


>UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=4; Enterobacteriaceae|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Buchnera aphidicola subsp.
           Schizaphis graminum
          Length = 923

 Score = 35.5 bits (78), Expect = 1.7
 Identities = 39/196 (19%), Positives = 81/196 (41%), Gaps = 1/196 (0%)
 Frame = +3

Query: 90  FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVP 269
           +L+G++  Y+E +Y ++L +P SV  +W   F +                L+   KN + 
Sbjct: 14  WLSGNNQNYIEKIYESYLINPKSVDITWQDKFSD----------------LSKKRKNILK 57

Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449
               V  +     I       ++I++    +  II +++ +G+  + +DPL ++      
Sbjct: 58  EEKFVYKNNSFKEIKIDK---QEILEKK--INYIINTFRKKGYKKSLIDPLKLNEQKKYK 112

Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629
             +                   F E ++ +  K+    F    +  + +R++  +L   Y
Sbjct: 113 YLE--------------PTFYHFSEDELKKTVKID---FKNSSQYEIKIRDLYEQLNNKY 155

Query: 630 CNNIGIEFMFI-NSLE 674
           C +IG E+M+I NS E
Sbjct: 156 CGSIGFEYMYIENSFE 171


>UniRef50_Q02C37 Cluster: Putative uncharacterized protein; n=1;
           Solibacter usitatus Ellin6076|Rep: Putative
           uncharacterized protein - Solibacter usitatus (strain
           Ellin6076)
          Length = 365

 Score = 35.1 bits (77), Expect = 2.2
 Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
 Frame = +3

Query: 393 GHLVAQLDPLGISTGDPVSSADWHGGMRAF-ANEAVIRQHVRFDEADMDRVFKLPSTTF 566
           G L   L+ LG         A  H GMR   A +A +  HV   E D+DR F LP  T+
Sbjct: 69  GELAFFLESLGYQVVAADHPAYNHNGMRGIRALKAALGSHVEIHEIDVDRPFTLPHDTY 127


>UniRef50_UPI0000F2D68A Cluster: PREDICTED: hypothetical protein;
           n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
           protein - Monodelphis domestica
          Length = 522

 Score = 34.7 bits (76), Expect = 3.0
 Identities = 18/41 (43%), Positives = 24/41 (58%)
 Frame = -1

Query: 553 GSLNTLSMSASSNLTCCLMTASLAKARMPPCQSALDTGSPV 431
           G L+ L     S +T CL+TA  AKA+ PP   ALD G+ +
Sbjct: 177 GKLDFLVFDYLSEITMCLLTA--AKAKSPPISRALDLGADI 215


>UniRef50_Q0RQH6 Cluster: Putative LuxR-family transcriptional
            regulator; n=2; Bacteria|Rep: Putative LuxR-family
            transcriptional regulator - Frankia alni (strain ACN14a)
          Length = 1436

 Score = 34.7 bits (76), Expect = 3.0
 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
 Frame = +3

Query: 201  GAQPGAAYTPPPNLA-PYNKNEVPLTSLVPSSGGMPSISAGSP 326
            G++P   Y PPP  + P     V  +   P  GG P++ AGSP
Sbjct: 1263 GSRPSGGYAPPPGRSEPERGTPVVGSPKAPGVGGPPAVGAGSP 1305


>UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=1; Dichelobacter nodosus VCS1703A|Rep:
           2-oxoglutarate dehydrogenase, E1 component -
           Dichelobacter nodosus (strain VCS1703A)
          Length = 917

 Score = 34.7 bits (76), Expect = 3.0
 Identities = 30/128 (23%), Positives = 55/128 (42%)
 Frame = +3

Query: 69  SSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAP 248
           + TA +   +  ++AY+E +Y  +L  P+SV   W  +F      + P          A 
Sbjct: 2   TKTAQKSAYSSENAAYLEQLYEHYLTQPDSVAPQWQNYFERLNQQSSP----------AF 51

Query: 249 YNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGI 428
              +E   T+         S+   +   +K     + V  +IR+Y+ RGH  A LDPL  
Sbjct: 52  MTHSEHAATA---------SVQENAAHGQK----QIGVLNLIRAYRVRGHRHAHLDPLTN 98

Query: 429 STGDPVSS 452
           +  + +++
Sbjct: 99  APSEDIAA 106


>UniRef50_A0LLC1 Cluster: Putative uncharacterized protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Putative
           uncharacterized protein - Syntrophobacter fumaroxidans
           (strain DSM 10017 / MPOB)
          Length = 392

 Score = 34.7 bits (76), Expect = 3.0
 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
 Frame = +3

Query: 486 NEAVIRQH-VRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQA 626
           N+ +I  H   +DEAD  R +       +GE E ALPL+ I  ++EQ+
Sbjct: 92  NQTIIDSHPTEWDEADFRRNWSQFLQMLVGENENALPLKRIQYQVEQS 139


>UniRef50_A5DZM2 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 807

 Score = 34.3 bits (75), Expect = 3.9
 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 3/103 (2%)
 Frame = +3

Query: 27  PQTAAVSVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWD---AFFRNAT 197
           PQT+  + NA   + S   +PF+  S   +  T + A  A+ NS +        FF + +
Sbjct: 653 PQTSQGAQNALASQGSQVPQPFIPQSQVPFQATQF-ATPANTNSFNGPGYYPIPFFYHPS 711

Query: 198 NGAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSP 326
                 A Y PPP L P++    P T L P       I+   P
Sbjct: 712 ASGIAYATYQPPPALLPHHAYPAPPT-LYPMKNFKQPIAVAQP 753


>UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
           Bacillus sp. B14905|Rep: Alpha-ketoglutarate
           decarboxylase - Bacillus sp. B14905
          Length = 670

 Score = 33.9 bits (74), Expect = 5.2
 Identities = 15/40 (37%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
 Frame = +1

Query: 682 NWIRQRMEPPNVTK-MNADQKRLILARLTRSTGFENFLAK 798
           NWI+ ++E  +  + +++D+K+ +L RLTR   FE F+ K
Sbjct: 181 NWIQAQIESGSFQQALSSDEKKALLDRLTRVENFEKFIHK 220


>UniRef50_A7QD53 Cluster: Chromosome undetermined scaffold_80, whole
           genome shotgun sequence; n=2; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_80, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 648

 Score = 33.9 bits (74), Expect = 5.2
 Identities = 17/56 (30%), Positives = 32/56 (57%)
 Frame = +3

Query: 513 RFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLETM 680
           +F+E++   +  L ST F GE   ++ + + L  L+ ++CN  G   +FI SL+ +
Sbjct: 246 KFNESNSILLLDLSSTNFSGELPSSISILKSLESLDLSHCNFSGSIPLFIASLDNL 301


>UniRef50_Q4QJD5 Cluster: Putative uncharacterized protein; n=2;
            Leishmania|Rep: Putative uncharacterized protein -
            Leishmania major
          Length = 2544

 Score = 33.9 bits (74), Expect = 5.2
 Identities = 25/110 (22%), Positives = 49/110 (44%), Gaps = 1/110 (0%)
 Frame = +3

Query: 141  LADPNSVHASWDAFFRNATNGAQPGAAYTPP-PNLAPYNKNEVPLTSLVPSSGGMPSISA 317
            +A+ +S + S  +        +Q GAA   P P     +K+  P+ +   S+   P+ +A
Sbjct: 2007 VAESSSSNRSASSVLSFHVEDSQEGAALQQPGPGSDGADKDHYPVAASGSSAAAAPA-AA 2065

Query: 318  GSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHG 467
              P +++      A    + +  +     A+  PL I  G+P++ +D HG
Sbjct: 2066 AQPSSDESTSPVTAAVDSLATPSTASPQAAEGRPLSIDRGEPITDSDRHG 2115


>UniRef50_UPI0000DD7C6C Cluster: PREDICTED: hypothetical protein;
           n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
           Homo sapiens
          Length = 241

 Score = 33.5 bits (73), Expect = 6.8
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 162 HASWDAFFRNATNGAQPGAAYTPP 233
           HA W AFFR +++   PG A TPP
Sbjct: 47  HAGWTAFFRGSSSVRVPGPASTPP 70


>UniRef50_Q395C1 Cluster: Rhs family protein; n=6; Burkholderia|Rep:
           Rhs family protein - Burkholderia sp. (strain 383)
           (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
           R18194))
          Length = 1429

 Score = 33.5 bits (73), Expect = 6.8
 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = +3

Query: 273 TSLVPSSGGMPSISAGSP-INEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTG 437
           TS++  +G +  IS     + E+I D   A Q   R Y ++GHL ++ DPLG  TG
Sbjct: 551 TSIIDPAGQVTRISYNDRNLPEQITDP--AGQVWQRGYDAQGHLTSETDPLGNVTG 604


>UniRef50_A4U1B6 Cluster: Secreted protein; n=1; Magnetospirillum
           gryphiswaldense|Rep: Secreted protein - Magnetospirillum
           gryphiswaldense
          Length = 357

 Score = 33.5 bits (73), Expect = 6.8
 Identities = 32/139 (23%), Positives = 59/139 (42%), Gaps = 9/139 (6%)
 Frame = +3

Query: 12  WLLNKPQTAAVSVNANRLKSSTAAEPFLNGSSSAYVETMYNAW----LADPNSVHASWDA 179
           W L   Q +A+  +A  +++S A       + +A V     A     LA+PN     +D 
Sbjct: 200 WFLR--QNSALYDSAKAIRASLAQSAIRADNHAAPVNAADGATAAVALAEPNIPFDEYDR 257

Query: 180 FFRNATN-----GAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKII 344
            F   T+     GAQ   A+ P P ++  N+        +    G+P ++ G+ + ++  
Sbjct: 258 LFNQFTDAVLASGAQLIVAFLPGPGVSQTNERIGEFIDTLSRQRGLPFLNLGTALADRSA 317

Query: 345 DDHLAVQAIIRSYQSRGHL 401
           D+   ++    +Y S  HL
Sbjct: 318 DEIYLMRQNDPTYPSDIHL 336


>UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase, E1
           subunit; n=3; cellular organisms|Rep: Predicted
           2-oxoglutarate dehydrogenase, E1 subunit - Ostreococcus
           tauri
          Length = 1210

 Score = 33.5 bits (73), Expect = 6.8
 Identities = 16/36 (44%), Positives = 22/36 (61%)
 Frame = +3

Query: 330 NEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTG 437
           +E    D L +  + R+ ++RGHL A LDPLG S G
Sbjct: 58  SEAASHDALRLIELARAVRARGHLTASLDPLGRSLG 93


>UniRef50_Q5K6W4 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 394

 Score = 33.5 bits (73), Expect = 6.8
 Identities = 23/85 (27%), Positives = 46/85 (54%)
 Frame = +3

Query: 117 VETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSG 296
           + T+YN+ + D +     +  +    T+ +QP A+++ PP+++  N+   PL    PS  
Sbjct: 183 IHTIYNS-IEDQDIYTPIFVQWLPRITHPSQPSASFSHPPDMS--NRKGAPL----PSLS 235

Query: 297 GMPSISAGSPINEKIIDDHLAVQAI 371
           G+ + S+ S  N+ + +D LA + I
Sbjct: 236 GLCNHSSPSVDNQFLSEDFLAPEVI 260


>UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=14; Rickettsia|Rep: 2-oxoglutarate dehydrogenase E1
           component - Rickettsia felis (Rickettsia azadi)
          Length = 977

 Score = 33.5 bits (73), Expect = 6.8
 Identities = 12/32 (37%), Positives = 21/32 (65%)
 Frame = +3

Query: 90  FLNGSSSAYVETMYNAWLADPNSVHASWDAFF 185
           +L G ++ +V+ +Y  +LA+P SV  +W  FF
Sbjct: 10  YLFGGNAVFVDELYRQYLANPASVDQTWQEFF 41


>UniRef50_Q13118 Cluster: Krueppel-like factor 10; n=35;
           Amniota|Rep: Krueppel-like factor 10 - Homo sapiens
           (Human)
          Length = 480

 Score = 33.5 bits (73), Expect = 6.8
 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 2/105 (1%)
 Frame = +3

Query: 207 QPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSP-INEKIIDDHLAVQ-AIIRS 380
           QP    + PP ++P   N   L+ + P+ G  PS +  +P I+   I  H+       ++
Sbjct: 323 QPVVQSSKPPVVSP---NGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKT 379

Query: 381 YQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVR 515
           Y    HL A        TG+   S  W G  R FA    + +H R
Sbjct: 380 YFKSSHLKAHTRT---HTGEKPFSCSWKGCERRFARSDELSRHRR 421


>UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2,
           aspartate transcarbamylase, and dihydroorotase; n=23;
           Coelomata|Rep: Carbamoyl-phosphate synthetase 2,
           aspartate transcarbamylase, and dihydroorotase - Danio
           rerio (Zebrafish) (Brachydanio rerio)
          Length = 2154

 Score = 33.1 bits (72), Expect = 9.0
 Identities = 12/46 (26%), Positives = 21/46 (45%)
 Frame = +3

Query: 99  GSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPP 236
           G+S  Y+ +  + +  DP ++   WD  F NA +    G  +   P
Sbjct: 288 GTSRCYITSQNHGFAVDPETLPKDWDVLFTNANDQTSEGIVHNHKP 333


>UniRef50_Q2JGL1 Cluster: Rieske (2Fe-2S) protein; n=7;
           Actinomycetales|Rep: Rieske (2Fe-2S) protein - Frankia
           sp. (strain CcI3)
          Length = 365

 Score = 33.1 bits (72), Expect = 9.0
 Identities = 16/32 (50%), Positives = 18/32 (56%)
 Frame = +2

Query: 317 RFPYKREDNRRSPRRAGYHQELPVEGSSCGAT 412
           RF  +RE   RSP+  GY  ELP  GS C  T
Sbjct: 24  RFERERELVLRSPQLVGYRSELPAPGSYCTKT 55


>UniRef50_A1IAX2 Cluster: Outer membrane lipoprotein-sorting
           protein-like precursor; n=1; Candidatus Desulfococcus
           oleovorans Hxd3|Rep: Outer membrane lipoprotein-sorting
           protein-like precursor - Candidatus Desulfococcus
           oleovorans Hxd3
          Length = 229

 Score = 33.1 bits (72), Expect = 9.0
 Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
 Frame = +3

Query: 588 LPLREILNRLEQAY-CNNIGIEFMFINSLETMQLDPTAHGA 707
           LP+ EIL+R+E  Y C+    +F   ++L+ M +  TA G+
Sbjct: 33  LPVEEILSRVEARYDCDTFAADFFQTSTLKAMDITDTAEGS 73


>UniRef50_Q8S6C0 Cluster: Putative uncharacterized protein
           OJ1004_D04.4; n=1; Oryza sativa (japonica
           cultivar-group)|Rep: Putative uncharacterized protein
           OJ1004_D04.4 - Oryza sativa subsp. japonica (Rice)
          Length = 503

 Score = 33.1 bits (72), Expect = 9.0
 Identities = 15/37 (40%), Positives = 21/37 (56%)
 Frame = +3

Query: 231 PPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKI 341
           PP+ +P     VP TS  PS+   PS S+ SPI + +
Sbjct: 345 PPSSSPVVPRSVPCTSAGPSTSAPPSSSSSSPIKKAL 381


>UniRef50_Q01A93 Cluster: Chromosome 04 contig 1, DNA sequence; n=3;
           Ostreococcus|Rep: Chromosome 04 contig 1, DNA sequence -
           Ostreococcus tauri
          Length = 334

 Score = 33.1 bits (72), Expect = 9.0
 Identities = 18/59 (30%), Positives = 27/59 (45%)
 Frame = +3

Query: 63  LKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPN 239
           L  +T AEP++  +    V  +   WL++ ++  A W   F N     QPGA     PN
Sbjct: 248 LNETTDAEPYMTQAQRDKVREIAG-WLSESDAGKALWHVHFGNPAEEFQPGAPGALTPN 305


>UniRef50_Q55GQ4 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 567

 Score = 33.1 bits (72), Expect = 9.0
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 8/85 (9%)
 Frame = +3

Query: 282 VPSSGGMPSISAGSP--INEKIIDDHLA----VQAIIRSYQSRGHLVAQLDPLGISTGDP 443
           V SS    S S+ SP  + +  I+DH++      +II   +S+GH++ QL P       P
Sbjct: 34  VESSSSSSSTSSRSPSVVFKSYINDHISNNERYTSIINHIESKGHIIEQLHPYSSLPSSP 93

Query: 444 VSSADWH--GGMRAFANEAVIRQHV 512
            +   +   G  +  +N  +++ H+
Sbjct: 94  SNDIHYATIGSDKLLSNLPLLKDHI 118


>UniRef50_Q9UU85 Cluster: Protein kinase domain-containing protein
           ppk38; n=1; Schizosaccharomyces pombe|Rep: Protein
           kinase domain-containing protein ppk38 -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 650

 Score = 33.1 bits (72), Expect = 9.0
 Identities = 33/148 (22%), Positives = 61/148 (41%), Gaps = 3/148 (2%)
 Frame = +3

Query: 24  KPQTAAVSVNANRLKSSTAAEPFLNGSSSAYVETM-YNAWLADPNSVHASWDAFFRNATN 200
           KP  + +  N N +   +  +   NG++S+ V    Y    ++  S       F    T 
Sbjct: 360 KPMASPMLPNVNSMPYLSNGDHNNNGNTSSPVSRFSYGQHTSNVPSTQKLPSNF--RVTQ 417

Query: 201 GAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRS 380
           GA P   Y PPP + P  K ++  T+   S+  +      S   E +  +       ++S
Sbjct: 418 GAPPSHTYGPPPPVQP--KPKISPTTPRLSTLALADDMFSSTAKETVPTNEAVFTGDVKS 475

Query: 381 YQSRGHLVAQLDPLGIS--TGDPVSSAD 458
           + S+   + + +PL  S  +G P +S +
Sbjct: 476 FDSQESNIIESEPLSASNASGKPRTSVN 503


>UniRef50_Q4IER0 Cluster: Leucine carboxyl methyltransferase 2; n=1;
            Gibberella zeae|Rep: Leucine carboxyl methyltransferase 2
            - Gibberella zeae (Fusarium graminearum)
          Length = 989

 Score = 33.1 bits (72), Expect = 9.0
 Identities = 19/88 (21%), Positives = 39/88 (44%)
 Frame = +3

Query: 45   SVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAY 224
            +++ ++L S+   E FLN     ++  M+    +    +  + + FFR+  +G   G   
Sbjct: 885  ALDTHQLASTNPHEAFLNPGDLLFIPAMWFHTASPVTDLSVAVNVFFRDLESGYSTGRDV 944

Query: 225  TPPPNLAPYNKNEVPLTSLVPSSGGMPS 308
                +LA Y K    ++ +  S   +PS
Sbjct: 945  YGNRDLAAYEKGRQDISRITKSFDRLPS 972


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 878,546,051
Number of Sequences: 1657284
Number of extensions: 18567888
Number of successful extensions: 62304
Number of sequences better than 10.0: 78
Number of HSP's better than 10.0 without gapping: 58552
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 62203
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 74193458591
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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