BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= FWDP01_FL5_E11 (847 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 193 4e-48 UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome s... 149 7e-35 UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH... 127 4e-28 UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albica... 120 6e-26 UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;... 117 3e-25 UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1; ... 116 1e-24 UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; ... 112 1e-23 UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 105 1e-21 UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC... 104 2e-21 UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole gen... 61 2e-18 UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridipla... 59 2e-17 UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 89 1e-16 UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergil... 75 2e-12 UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 75 2e-12 UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, who... 75 3e-12 UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 70 6e-11 UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 69 2e-10 UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacte... 67 6e-10 UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 66 1e-09 UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 63 7e-09 UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 61 3e-08 UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1; Opitut... 44 3e-08 UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 60 7e-08 UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1... 60 9e-08 UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 59 2e-07 UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 58 4e-07 UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 54 3e-06 UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E... 53 1e-05 UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 52 2e-05 UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 50 6e-05 UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr... 50 1e-04 UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 49 2e-04 UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 48 3e-04 UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 48 4e-04 UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 47 7e-04 UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 46 0.001 UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 compone... 46 0.001 UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 46 0.002 UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 45 0.002 UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 44 0.004 UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 44 0.004 UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 43 0.008 UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 42 0.026 UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 42 0.026 UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 41 0.045 UniRef50_A5XEI0 Cluster: Oxoglutarate (Alpha-ketoglutarate) dehy... 39 0.14 UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ... 39 0.18 UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 38 0.32 UniRef50_Q2JFB9 Cluster: Putative uncharacterized protein; n=1; ... 37 0.73 UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 36 0.97 UniRef50_Q8UDS8 Cluster: Short chain dehydrogenase; n=1; Agrobac... 36 1.3 UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, p... 36 1.7 UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 36 1.7 UniRef50_Q02C37 Cluster: Putative uncharacterized protein; n=1; ... 35 2.2 UniRef50_UPI0000F2D68A Cluster: PREDICTED: hypothetical protein;... 35 3.0 UniRef50_Q0RQH6 Cluster: Putative LuxR-family transcriptional re... 35 3.0 UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 35 3.0 UniRef50_A0LLC1 Cluster: Putative uncharacterized protein; n=1; ... 35 3.0 UniRef50_A5DZM2 Cluster: Putative uncharacterized protein; n=1; ... 34 3.9 UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 34 5.2 UniRef50_A7QD53 Cluster: Chromosome undetermined scaffold_80, wh... 34 5.2 UniRef50_Q4QJD5 Cluster: Putative uncharacterized protein; n=2; ... 34 5.2 UniRef50_UPI0000DD7C6C Cluster: PREDICTED: hypothetical protein;... 33 6.8 UniRef50_Q395C1 Cluster: Rhs family protein; n=6; Burkholderia|R... 33 6.8 UniRef50_A4U1B6 Cluster: Secreted protein; n=1; Magnetospirillum... 33 6.8 UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase,... 33 6.8 UniRef50_Q5K6W4 Cluster: Putative uncharacterized protein; n=1; ... 33 6.8 UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 33 6.8 UniRef50_Q13118 Cluster: Krueppel-like factor 10; n=35; Amniota|... 33 6.8 UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspar... 33 9.0 UniRef50_Q2JGL1 Cluster: Rieske (2Fe-2S) protein; n=7; Actinomyc... 33 9.0 UniRef50_A1IAX2 Cluster: Outer membrane lipoprotein-sorting prot... 33 9.0 UniRef50_Q8S6C0 Cluster: Putative uncharacterized protein OJ1004... 33 9.0 UniRef50_Q01A93 Cluster: Chromosome 04 contig 1, DNA sequence; n... 33 9.0 UniRef50_Q55GQ4 Cluster: Putative uncharacterized protein; n=1; ... 33 9.0 UniRef50_Q9UU85 Cluster: Protein kinase domain-containing protei... 33 9.0 UniRef50_Q4IER0 Cluster: Leucine carboxyl methyltransferase 2; n... 33 9.0 >UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor; n=77; Eumetazoa|Rep: 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor - Homo sapiens (Human) Length = 1002 Score = 193 bits (471), Expect = 4e-48 Identities = 117/269 (43%), Positives = 148/269 (55%), Gaps = 3/269 (1%) Frame = +3 Query: 21 NKPQTAAVSVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATN 200 N+P A + AAEPFL+G+SS YVE MY AWL +P SVH SWD FFRN Sbjct: 26 NRPAAARTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNA 85 Query: 201 GAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRS 380 GA PG AY P P ++ + + S + P +K+++DHLAVQ++IR+ Sbjct: 86 GAPPGTAYQSP---LPLSRGSLAAVAHAQS------LVEAQPNVDKLVEDHLAVQSLIRA 136 Query: 381 YQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPST 560 YQ RGH VAQLDPLGI D SS + DE+D+D+VF LP+T Sbjct: 137 YQIRGHHVAQLDPLGILDADLDSSVP-----ADIISSTDKLGFYGLDESDLDKVFHLPTT 191 Query: 561 TFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLETMQ---LDPTAHGATERNKDER 731 TFIG +E ALPLREI+ RLE AYC +IG+EFMFIN LE Q G + +E+ Sbjct: 192 TFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEK 251 Query: 732 *PEEAHPGSSNQINWVREFPR*KWSSEXR 818 A S + EF + KWSSE R Sbjct: 252 RTLLARLVRSTRF---EEFLQRKWSSEKR 277 >UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 17 SCAF14563, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1054 Score = 149 bits (362), Expect = 7e-35 Identities = 89/216 (41%), Positives = 115/216 (53%) Frame = +3 Query: 36 AAVSVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPG 215 AA V+ S P S+ +YVE MY +WL DP SVH SWD FFRN Sbjct: 38 AAGVVDRRSCSSGAVTGPSALTSNPSYVEEMYFSWLEDPKSVHKSWDMFFRNMEASPSGE 97 Query: 216 AAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRG 395 AA P L ++S S + +K+++DHLAV +IR+YQ+RG Sbjct: 98 AADRRPSTLLRGR-----------------TLSHSSDVAQKVVEDHLAVHTLIRAYQTRG 140 Query: 396 HLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGE 575 H VAQLDPLGI D S + E+D+DR F+LPSTTFIG Sbjct: 141 HHVAQLDPLGILEADLDSFVP-----SDLITSIDKLGYYDLKESDLDRSFQLPSTTFIGG 195 Query: 576 KEKALPLREILNRLEQAYCNNIGIEFMFINSLETMQ 683 ++ LPLREI+ RLE AYC +IG+EFMFIN+++ Q Sbjct: 196 EDSTLPLREIIRRLEMAYCGHIGVEFMFINNVDQCQ 231 Score = 50.4 bits (115), Expect = 6e-05 Identities = 21/41 (51%), Positives = 28/41 (68%) Frame = +1 Query: 676 QCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAK 798 QC WIR ++E P + + KR +LARL RST FE+FLA+ Sbjct: 229 QCQWIRNKIETPGIMRFTDADKRTLLARLIRSTRFEDFLAR 269 >UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH protein - Homo sapiens (Human) Length = 640 Score = 127 bits (306), Expect = 4e-28 Identities = 82/179 (45%), Positives = 106/179 (59%), Gaps = 14/179 (7%) Frame = +3 Query: 324 PINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSS--ADWHGGMRAFANEAV 497 P +K+++DHLAVQ++IR+YQ RGH VAQLDPLGI D SS AD + AV Sbjct: 9 PNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKL-DLAV 67 Query: 498 IRQHVRF---------DEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIE 650 ++ +R DE+D+D+VF LP+TTFIG +E ALPLREI+ RLE AYC +IG+E Sbjct: 68 FKERLRMLTVGGFYGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVE 127 Query: 651 FMFINSLETMQ---LDPTAHGATERNKDER*PEEAHPGSSNQINWVREFPR*KWSSEXR 818 FMFIN LE Q G + +E+ A S + EF + KWSSE R Sbjct: 128 FMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRF---EEFLQRKWSSEKR 183 >UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albicans CaKGD1 2-oxoglutarate dehydrogenase; n=4; Ascomycota|Rep: Similar to CA3149|CaKGD1 Candida albicans CaKGD1 2-oxoglutarate dehydrogenase - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 997 Score = 120 bits (288), Expect = 6e-26 Identities = 72/205 (35%), Positives = 109/205 (53%), Gaps = 4/205 (1%) Frame = +3 Query: 72 STAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNA-TNGAQPGAAYTPPPNLAP 248 +T + FL +++ Y++ MY AW DP+SVH SW+A+F+N ++ P A+T PP + P Sbjct: 27 ATGQDSFLLSNNANYIDEMYAAWKHDPSSVHISWNAYFKNIESSNVPPSKAFTAPPTIIP 86 Query: 249 YNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGI 428 + G + SP NE ++ HL VQ ++R+YQ RGH A++DPLGI Sbjct: 87 -----------TVAGGAAGFVPGSSPTNEDVVT-HLKVQLLVRAYQVRGHQKAKIDPLGI 134 Query: 429 STGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKL-PSTT--FIGEKEKALPLR 599 S GD + + +H F EADMD+ L P F +K+L LR Sbjct: 135 SFGD-----------NDVVPKELTLEHYGFTEADMDKQITLGPGILPRFAEGGKKSLTLR 183 Query: 600 EILNRLEQAYCNNIGIEFMFINSLE 674 EI++ E+ YC + G+E++ I S E Sbjct: 184 EIISNCERLYCQSYGVEYIHIPSKE 208 Score = 48.0 bits (109), Expect = 3e-04 Identities = 24/49 (48%), Positives = 32/49 (65%), Gaps = 1/49 (2%) Frame = +1 Query: 664 IPWK-QCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKNGP 807 IP K QC+W+R+R+E P K + D+KR IL R+ S FE+FLA P Sbjct: 204 IPSKEQCDWLRERIEIPEPYKYSPDEKRQILDRVIWSCSFESFLASKFP 252 >UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein; n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical protein - Nasonia vitripennis Length = 1012 Score = 117 bits (282), Expect = 3e-25 Identities = 74/228 (32%), Positives = 113/228 (49%), Gaps = 12/228 (5%) Frame = +3 Query: 84 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNE 263 + FL +SS Y+E +++ W DP+SV SWD +FR +GA G + + + Sbjct: 31 DSFLTQTSSQYIEHLFSKWRKDPSSVPESWDVYFRKVESGAPLGPSPRKSSLKSSSKMQD 90 Query: 264 VPLTSLVPSS-----GGMPSISAGSPIN---EKIIDDHLAVQAIIRSYQSRGHLVAQLDP 419 VP L P + S E ++ L + A IRSYQ+RGHL+A +DP Sbjct: 91 VPANLLGAQRIEYDLMTKPRVRLKSEAEIQGEAYVESTLDINATIRSYQARGHLIADIDP 150 Query: 420 LGISTGDPVSSADWHGGMRAFANEAVIRQHVR-FDEADMDRVFKLPSTTFIGEKEKALPL 596 LGI D + V+R+H++ E D++R F L + T IG + LPL Sbjct: 151 LGIQNPDSARLQNTSD----LPPRLVVREHLKGMTETDLNREFPLGTITVIGGDRETLPL 206 Query: 597 REILNRLEQAYCNNIGIEFMFINS---LETMQLDPTAHGATERNKDER 731 REI+ RL + YC ++G+E+++I+ LE ++ GA E D R Sbjct: 207 REIIKRLNKVYCGHLGLEYIYIHDSTVLEWLRYKFEIPGAWELAADHR 254 Score = 35.9 bits (79), Expect = 1.3 Identities = 14/38 (36%), Positives = 23/38 (60%) Frame = +1 Query: 685 WIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAK 798 W+R + E P ++ AD ++ I + ++ FENFLAK Sbjct: 236 WLRYKFEIPGAWELAADHRKWIWVNIMKAVTFENFLAK 273 >UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 334 Score = 116 bits (278), Expect = 1e-24 Identities = 79/231 (34%), Positives = 123/231 (53%), Gaps = 9/231 (3%) Frame = +3 Query: 9 SWLLNKPQTAAVSVNANRLKSSTAA-----EPFLNGSSSAYVETMYNAWLADPNSVHASW 173 S L +K ++ A+ ++ R +S+TA+ + FL+G+++ Y++ MY W DP+SVH SW Sbjct: 35 SALSSKRRSLAI-ISQKRHESTTASATDLNDSFLSGNTANYIDEMYMQWKEDPSSVHISW 93 Query: 174 DAFFRNATNGAQP-GAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDD 350 +FRN +G P A+TPPP L P VP S +P GG + GS + + Sbjct: 94 QVYFRNMESGDMPMSQAFTPPPTLVPTPTGGVP--SFLPGLGG----AEGSEVT-----N 142 Query: 351 HLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEAD 530 HL VQ + R+YQ+RGH A +DPLGI A+ G + + + +H +F E D Sbjct: 143 HLKVQLLCRAYQARGHHKADIDPLGIR-----REAEEFGYSKP---KELQLEHYQFSEKD 194 Query: 531 MDRVFKL-PSTT--FIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLE 674 +D + L P F + + LREI+ E+ YC + G+E++ I E Sbjct: 195 LDTEYSLGPGILPHFKKSGREKMTLREIIAACERIYCGSYGVEYIHIPDRE 245 Score = 45.2 bits (102), Expect = 0.002 Identities = 21/45 (46%), Positives = 29/45 (64%) Frame = +1 Query: 673 KQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKNGP 807 +QC+W+R R+E K + D+KR IL RL S+ FE+FLA P Sbjct: 245 EQCDWLRARIEVDKPFKYSIDEKRRILDRLIWSSSFESFLATKYP 289 >UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 1013 Score = 112 bits (269), Expect = 1e-23 Identities = 71/201 (35%), Positives = 104/201 (51%), Gaps = 3/201 (1%) Frame = +3 Query: 81 AEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKN 260 +E FL+G+SS YVE M+ W+ DP SVH SW +FF ++ G G A+ PP L Sbjct: 45 SESFLDGTSSTYVEDMFANWVKDPKSVHPSWASFFESSERGVPAGEAFMSPPTL-----G 99 Query: 261 EVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGD 440 T PS+ S+GSP K + D + + ++R+YQ RGH +A LDPLG+ + Sbjct: 100 SSVATKATPST----YTSSGSP---KQVSDSMRLLLLVRAYQVRGHALANLDPLGLEVKE 152 Query: 441 PVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPS---TTFIGEKEKALPLREILN 611 A+++ F EADMDR + + F+ K+ LR++L Sbjct: 153 --EPAEFNPAKYGFT------------EADMDRPIFVGEGFISGFLTNKQPETTLRQVLK 198 Query: 612 RLEQAYCNNIGIEFMFINSLE 674 RL++ YC +IGIE+M I E Sbjct: 199 RLKETYCGDIGIEYMHIQDRE 219 >UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor; n=34; Fungi/Metazoa group|Rep: 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor - Saccharomyces cerevisiae (Baker's yeast) Length = 1014 Score = 105 bits (253), Expect = 1e-21 Identities = 66/204 (32%), Positives = 109/204 (53%), Gaps = 4/204 (1%) Frame = +3 Query: 69 SSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGA-AYTPPPNLA 245 ++T + FL+ S++ Y++ MY AW DP+SVH SWDA+F+N +N P A+ PP+++ Sbjct: 37 ATTGTDNFLSTSNATYIDEMYQAWQKDPSSVHVSWDAYFKNMSNPKIPATKAFQAPPSIS 96 Query: 246 PYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLG 425 + + T P M GS ++E + HL VQ + R+YQ RGHL A +DPLG Sbjct: 97 NFPQG----TEAAPLGTAM----TGS-VDEN-VSIHLKVQLLCRAYQVRGHLKAHIDPLG 146 Query: 426 ISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKL-PS--TTFIGEKEKALPL 596 IS G ++ + + F + D+D+ L P F + + + L Sbjct: 147 ISFGSNKNNP---------VPPELTLDYYGFSKHDLDKEINLGPGILPRFARDGKSKMSL 197 Query: 597 REILNRLEQAYCNNIGIEFMFINS 668 +EI++ LE+ YC++ G+++ I S Sbjct: 198 KEIVDHLEKLYCSSYGVQYTHIPS 221 Score = 50.8 bits (116), Expect = 4e-05 Identities = 25/49 (51%), Positives = 33/49 (67%), Gaps = 1/49 (2%) Frame = +1 Query: 664 IPWKQ-CNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKNGP 807 IP KQ C+W+R+R+E P + DQKR IL RLT +T FE+FL+ P Sbjct: 219 IPSKQKCDWLRERIEIPEPYQYTVDQKRQILDRLTWATSFESFLSTKFP 267 >UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC, isoform C; n=1; Apis mellifera|Rep: PREDICTED: similar to CG33791-PC, isoform C - Apis mellifera Length = 980 Score = 104 bits (250), Expect = 2e-21 Identities = 65/194 (33%), Positives = 101/194 (52%), Gaps = 5/194 (2%) Frame = +3 Query: 105 SSAYVETMYNAWLADPNSVHASWDAFFR---NATNGAQPGAAYTPPPNLAPYNKNEVPLT 275 S Y+E MY +W DP+SV SW+ +F+ ++ + + P + + P + Sbjct: 3 SIQYLEYMYQSWKKDPSSVSDSWNRYFKLIDEKDKKSEAASHKSSPKSTSSSTHGGSPSS 62 Query: 276 SLVPSSGGMPSISAGSPIN-EKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSS 452 S + S + +K I + A IR+YQ+RGHL+A DPLGI +P S Sbjct: 63 QSTKSPEQNAKSKSNSDMQGDKYIIGAFDINATIRAYQARGHLIADTDPLGIQ--NPESR 120 Query: 453 ADWHGGMRAFANEAVIRQHVR-FDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629 G V+RQ+++ EADM+R F L T IG +++LPLR+IL RL Q Y Sbjct: 121 K--LQGTPNLPPAIVVRQYLKGMTEADMNREFPLAPFTVIGGSKRSLPLRDILIRLNQVY 178 Query: 630 CNNIGIEFMFINSL 671 C ++G+E+ +I+ L Sbjct: 179 CGHLGLEYTYIHDL 192 Score = 34.3 bits (75), Expect = 3.9 Identities = 13/42 (30%), Positives = 23/42 (54%) Frame = +1 Query: 682 NWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKNGP 807 +W+R + E P + AD ++ I + ++ FE FLA+ P Sbjct: 196 DWLRDKFEIPGAWDLPADHRKFIWMNIMKAVTFEGFLARKFP 237 >UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr13 scaffold_17, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 973 Score = 60.9 bits (141), Expect(2) = 2e-18 Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 4/121 (3%) Frame = +3 Query: 312 SAGSP-INEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFAN 488 +A SP I+ + I + + + ++R+YQ GH+ A+LDPLG+ + D Sbjct: 107 AATSPGISGQTIQESMRLLLLVRAYQVNGHMKAKLDPLGLEEREIPDDLD---------- 156 Query: 489 EAVIRQHVRFDEADMDRVFKLP---STTFIGEKEKALPLREILNRLEQAYCNNIGIEFMF 659 A+ F EAD+DR F L F+ E LR IL RLEQAYC +IG E+M Sbjct: 157 PALYG----FTEADLDREFFLGVWRMAGFLSENRPVQTLRAILTRLEQAYCGSIGYEYMH 212 Query: 660 I 662 I Sbjct: 213 I 213 Score = 54.4 bits (125), Expect(2) = 2e-18 Identities = 23/40 (57%), Positives = 28/40 (70%) Frame = +3 Query: 72 STAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRN 191 S + FL+G+SS Y+E + AW ADPNSV SWD FFRN Sbjct: 63 SRLTDSFLDGTSSVYLEELQRAWEADPNSVDESWDNFFRN 102 Score = 45.6 bits (103), Expect = 0.002 Identities = 19/40 (47%), Positives = 27/40 (67%) Frame = +1 Query: 676 QCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLA 795 +CNW+R ++E P + N ++ +IL RL ST FENFLA Sbjct: 218 KCNWLRDKIETPTPRQYNQQRREVILDRLIWSTQFENFLA 257 >UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridiplantae|Rep: OSIGBa0096P03.7 protein - Oryza sativa (Rice) Length = 1016 Score = 59.3 bits (137), Expect(2) = 2e-17 Identities = 45/125 (36%), Positives = 60/125 (48%), Gaps = 4/125 (3%) Frame = +3 Query: 312 SAGSP-INEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFAN 488 +A SP I+ + I + + + ++R+YQ GHL A+LDPL + D AF Sbjct: 98 AATSPGISGQTIQESMRLLLLVRAYQVSGHLKAKLDPLALEERPIPDVLD-----PAFYG 152 Query: 489 EAVIRQHVRFDEADMDRVFKLP---STTFIGEKEKALPLREILNRLEQAYCNNIGIEFMF 659 F EAD+DR F L F+ E LR +L RLEQAYC IG E+M Sbjct: 153 ---------FSEADLDREFFLGVWRMAGFLSENRPVQTLRSVLERLEQAYCGTIGYEYMH 203 Query: 660 INSLE 674 I E Sbjct: 204 IPDRE 208 Score = 53.2 bits (122), Expect(2) = 2e-17 Identities = 26/56 (46%), Positives = 33/56 (58%) Frame = +3 Query: 24 KPQTAAVSVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRN 191 +PQ A V + S + FL+G+SS Y+E + AW ADP SV SWD FFRN Sbjct: 39 RPQRFATPV-PRAVPLSRLTDSFLDGTSSVYLEELQRAWEADPTSVDESWDNFFRN 93 Score = 44.4 bits (100), Expect = 0.004 Identities = 18/42 (42%), Positives = 31/42 (73%) Frame = +1 Query: 673 KQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAK 798 ++CNW+R R+E N + + D+++++L RL ST FE+FLA+ Sbjct: 208 EKCNWLRDRIETVNAREYSYDRRQVMLDRLMWSTQFESFLAQ 249 >UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 component, mitochondrial, putative; n=9; Plasmodium|Rep: 2-oxoglutarate dehydrogenase E1 component, mitochondrial, putative - Plasmodium vivax Length = 1059 Score = 89.0 bits (211), Expect = 1e-16 Identities = 61/201 (30%), Positives = 99/201 (49%), Gaps = 12/201 (5%) Frame = +3 Query: 96 NGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQP-GAAYTPPPNLAPYNKNEVPL 272 N S +AY+E Y W D NS+H SWD +F A P G+A PP + + + Sbjct: 34 NPSMAAYIEGAYRMWRQDRNSLHKSWDVYFAEMAEEAGPLGSA---PPRVLSTREVRSRM 90 Query: 273 TSLVPSSGGMPSISAGSPINEKIID--------DHLAVQAIIRSYQSRGHLVAQLDPLGI 428 + VP + ++ + +N++++D D + +IR YQ +GHL A ++PL + Sbjct: 91 GASVPQNRSSSNLRI-TYVNKEMLDKGRMGNIYDIARIVQLIRWYQKKGHLYANINPLPL 149 Query: 429 STGDPVSSA--DWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTT-FIGEKEKALPLR 599 P SS + ++++ + D+ D + F LPS T F K++ LR Sbjct: 150 PNVPPYSSVVNERDKNKMSYSDFGFTQ-----DDLDAEFEFDLPSITGFSSNKKETSTLR 204 Query: 600 EILNRLEQAYCNNIGIEFMFI 662 +++RLEQ YC IG E+M I Sbjct: 205 SLIDRLEQTYCGTIGFEYMHI 225 >UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergillus oryzae|Rep: RIB40 genomic DNA, SC005 - Aspergillus oryzae Length = 453 Score = 75.4 bits (177), Expect = 2e-12 Identities = 59/187 (31%), Positives = 88/187 (47%), Gaps = 4/187 (2%) Frame = +3 Query: 126 MYNAWLADPNSVHASWDAFFRNATNGAQP-GAAYTPPPNLAPYNKNEVPLTSLVPSSGGM 302 MY++W DP+SVH SW A+F N NG P A+ PP L + TS+ PSS Sbjct: 2 MYSSWKNDPSSVHLSWQAYFHNVENGHIPMDQAFMSPPGLVTASTR----TSIAPSSR-- 55 Query: 303 PSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAF 482 S + + L V +I++YQ GH A DPLG++ + Sbjct: 56 ---EDSSTVKQ------LKVIQLIQAYQRWGHEHASTDPLGMANEGKI------------ 94 Query: 483 ANEAVIRQHVRFDEADMDRVFKLPSTT---FIGEKEKALPLREILNRLEQAYCNNIGIEF 653 + + H E D+D V + + + F EK K PL E++ E+ YC+ +GIE+ Sbjct: 95 CRKELQLSHYGLSEQDLDLVLTVGTGSVQDFTSEKPK--PLWEVIAACEKTYCSTMGIEY 152 Query: 654 MFINSLE 674 M I++ E Sbjct: 153 MHISNQE 159 Score = 34.7 bits (76), Expect = 3.0 Identities = 16/45 (35%), Positives = 26/45 (57%) Frame = +1 Query: 673 KQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKNGP 807 +Q +WIR R+E + ++KR +L L R+T +E F+A P Sbjct: 159 EQVDWIRARIEGAQRHRFTDEEKRRMLHGLVRATSWEKFVATKFP 203 >UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=149; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Azotobacter vinelandii Length = 943 Score = 74.9 bits (176), Expect = 2e-12 Identities = 60/190 (31%), Positives = 93/190 (48%) Frame = +3 Query: 93 LNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVPL 272 L+G ++AYVE +Y +L DPN+V W +F A+ G + T P+ AP V L Sbjct: 15 LSGGNAAYVEELYELYLHDPNAVPEEWRTYFEKLP--AEAGTS-TDVPH-APVRDQFVLL 70 Query: 273 TSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSS 452 + + + S + +K ++ V +I++Y++RGH +QLDPLG+ Sbjct: 71 AKNQRRAQPVATSSVSTEHEKKQVE----VLRLIQAYRTRGHQASQLDPLGL-------- 118 Query: 453 ADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYC 632 W R ++ I H AD+D F+ +IG++E L REIL L++ YC Sbjct: 119 --WQ---RTAPSDLSIT-HYGLTNADLDTPFRT-GELYIGKEEATL--REILQALQETYC 169 Query: 633 NNIGIEFMFI 662 IG EF I Sbjct: 170 RTIGAEFTHI 179 >UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_5, whole genome shotgun sequence - Paramecium tetraurelia Length = 1002 Score = 74.5 bits (175), Expect = 3e-12 Identities = 57/205 (27%), Positives = 95/205 (46%), Gaps = 10/205 (4%) Frame = +3 Query: 90 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVP 269 FL ++ +++ + + W DPNSV A+WDA+FR + +TP P + Sbjct: 24 FLGAQNAEFLDNLLDKWSQDPNSVPATWDAYFRQVCESNK--FDFTPEPQKGQTISFQAD 81 Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449 + + S +S K++ DH V+ +I Y+ RGH + +DPL + + Sbjct: 82 VLLHIISK----QVSGV----RKLLSDHFRVRLLINKYRHRGHEKSMVDPLDLEHIQQI- 132 Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIG-EKEK---------ALPLR 599 G ++ + + R++ F E D+DR F + G KEK + LR Sbjct: 133 -----GKVKGYT-KLDYREY--FAEEDLDREFYIHDEVSSGISKEKQCNDLINYVVMKLR 184 Query: 600 EILNRLEQAYCNNIGIEFMFINSLE 674 +++N LE+AYC I E+M I S E Sbjct: 185 DLINYLEKAYCGKISYEYMHIQSTE 209 >UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=2; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E1 component - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 940 Score = 70.1 bits (164), Expect = 6e-11 Identities = 59/202 (29%), Positives = 90/202 (44%), Gaps = 2/202 (0%) Frame = +3 Query: 63 LKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNL 242 +K + P LN ++++Y+E +Y +L DPN+V A W +F+ G P Sbjct: 5 VKKQASPSP-LNAANASYLEALYEKFLKDPNTVPAHWRIWFKRLQAGV--------PEQA 55 Query: 243 APYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPL 422 AP P ++ PS+ PS + + + +AV +I +Y+ RGH A +DPL Sbjct: 56 APEFPARSPGPAVQPSA---PSAVMTEGLTAEAAEKQIAVLQLINAYRFRGHQKANIDPL 112 Query: 423 GISTGDPVSSAD--WHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPL 596 I VS D +HG E DM +VF S I + PL Sbjct: 113 RIYDRPVVSDLDPVFHG----------------LTEEDMGKVFSTGSLIGIDQ----APL 152 Query: 597 REILNRLEQAYCNNIGIEFMFI 662 EI +++ YC+ IG E+M I Sbjct: 153 EEIFALIKKIYCHTIGAEYMHI 174 >UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Haemophilus influenzae Length = 935 Score = 68.5 bits (160), Expect = 2e-10 Identities = 58/210 (27%), Positives = 94/210 (44%), Gaps = 4/210 (1%) Frame = +3 Query: 57 NRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPP 236 N+ A L G++ +Y+E +Y ++L+DP SV SW F + +TP Sbjct: 4 NKAFDDWLASTALGGANQSYIEELYESYLSDPQSVEESWRKTFDSLPKTTALEQPHTPVR 63 Query: 237 N----LAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLV 404 + LA N NE +T + P++G K++ V I +Y+ RGHL Sbjct: 64 DYFRRLARENHNEA-VTVIDPAAGA------------KLVK----VLQFINAYRFRGHLE 106 Query: 405 AQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEK 584 A LDPL +++ +F E R H F E D++ F + + K Sbjct: 107 ANLDPL-----------NYYRWKVSFVPELDYRHH-GFTEQDLNETFNINHYVY---KRD 151 Query: 585 ALPLREILNRLEQAYCNNIGIEFMFINSLE 674 + L E+ L++ YC +IG+EFM + +E Sbjct: 152 TIKLGELAQMLKETYCGSIGLEFMHVQDME 181 >UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacteria|Rep: Oxoglutarate dehydrogenase - Xylella fastidiosa Length = 967 Score = 66.9 bits (156), Expect = 6e-10 Identities = 64/214 (29%), Positives = 98/214 (45%) Frame = +3 Query: 42 VSVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAA 221 +S+ N +K T + P L G ++AY+E +Y +L PNSV W A+F + G G Sbjct: 23 LSIVDNLIKQFTQSSP-LAGGNAAYIEDLYEQYLVSPNSVDPKWKAYF-DGFKGRDAGD- 79 Query: 222 YTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHL 401 P++ +T S S S E+ I +I +Y+SRGHL Sbjct: 80 -------IPHSAVIAHITDTAKQSVKAKSRQDASDERERNIG------RLITAYRSRGHL 126 Query: 402 VAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKE 581 A++DPLG++ P S+ + + H +AD+D F ST IG + Sbjct: 127 SARIDPLGLT---PPSNPP----------DLDLPFH-HLSQADLDNEF---STGGIGGQP 169 Query: 582 KALPLREILNRLEQAYCNNIGIEFMFINSLETMQ 683 + + LR +L L+ Y + IG EFM I+ E Q Sbjct: 170 R-MKLRNLLAHLKATYTDTIGTEFMHISEFEQRQ 202 >UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=11; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Coxiella burnetii Length = 934 Score = 65.7 bits (153), Expect = 1e-09 Identities = 57/192 (29%), Positives = 92/192 (47%) Frame = +3 Query: 90 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVP 269 +L +++ Y+ET+Y +L DP+SV+ W ++FR TNGA TP + A + E Sbjct: 14 YLADNNAGYIETLYENFLKDPHSVNEEWRSYFRTLTNGAS-----TPDISHATI-REEFR 67 Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449 + P S +I+ + + AV +I Y+ GHL A+++PLG PV Sbjct: 68 ELARKPRSISPTAITPAA--------EQAAVDLLIEGYRRFGHLNAKINPLG--DNRPVD 117 Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629 S G H E+D ++ F +T + K KA L+EI RL + Y Sbjct: 118 SRLELG-------------HYNLTESDFNKTF---ATYGLLNKPKA-TLKEIYTRLREIY 160 Query: 630 CNNIGIEFMFIN 665 C +IG+++ I+ Sbjct: 161 CGSIGVQYSTIS 172 >UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=1; Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate dehydrogenase, E1 component - Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi) Length = 963 Score = 63.3 bits (147), Expect = 7e-09 Identities = 54/195 (27%), Positives = 85/195 (43%), Gaps = 5/195 (2%) Frame = +3 Query: 84 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRN-ATNGAQPGAAYTPPPNLAPYNKN 260 + FL ++ Y+E ++ +L DP S+ +SW FF+ N + T L YN Sbjct: 9 QSFLFRQNAEYIEHLHQKYLKDPASIDSSWITFFQEYCRNECEHPIVVTNKSEL-NYNNF 67 Query: 261 EVPLTSLVPSSGGMPSIS---AGSPINEKIID-DHLAVQAIIRSYQSRGHLVAQLDPLGI 428 L S + S + N+++I+ L +Q +I Y+S GHL A+LDPL + Sbjct: 68 RFKLASNNGVGSAISSTTNKLDDLDSNKQLINLKQLQIQQLIEVYRSNGHLCAKLDPLNL 127 Query: 429 STGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREIL 608 A H + F E D+D+ F T + LR ++ Sbjct: 128 QEQKTKEQA--HLSLNYFG----------LSEFDLDKNFHF---TLCNNFAQVSNLRTLI 172 Query: 609 NRLEQAYCNNIGIEF 653 ++LEQ YC NI +EF Sbjct: 173 SQLEQIYCGNIAVEF 187 >UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=12; root|Rep: 2-oxoglutarate dehydrogenase, E1 component - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 963 Score = 61.3 bits (142), Expect = 3e-08 Identities = 52/191 (27%), Positives = 83/191 (43%), Gaps = 1/191 (0%) Frame = +3 Query: 90 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATN-GAQPGAAYTPPPNLAPYNKNEV 266 +L G ++ YVE MY +LA+P SV +W +F + A G+ P+L N Sbjct: 20 YLFGGNAPYVEEMYENYLANPGSVPDNWRDYFDALQHVPAVDGSNAKDVPHLPVVN---- 75 Query: 267 PLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPV 446 + G + S + ++ A Q +I +Y++ G A LDPL + D + Sbjct: 76 --AFAERAKQGQTKVGEASGADSEMGRKRTATQQLIAAYRNVGARWADLDPLKRAERDKI 133 Query: 447 SSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQA 626 + F +AD + VF S TF G+ + LRE++N L + Sbjct: 134 PELE--------------PSFYGFTDADQETVFNT-SNTFFGKD--TMSLRELINALRET 176 Query: 627 YCNNIGIEFMF 659 YC IG E+M+ Sbjct: 177 YCGTIGAEYMY 187 >UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1; Opitutaceae bacterium TAV2|Rep: Oxoglutarate dehydrogenase - Opitutaceae bacterium TAV2 Length = 384 Score = 44.0 bits (99), Expect(2) = 3e-08 Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = +3 Query: 297 GMPSISAGSPINEKIIDDHLAVQA--IIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGG 470 G P I A + KIID + Q I +++S GHL A LDPLG + A Sbjct: 45 GSP-IGAAPASDIKIIDSYKQAQVGRFINAHRSHGHLEAHLDPLGDAPPPHPKLA----- 98 Query: 471 MRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIE 650 + +F + D+D F L T F G + + LR+I+ ++ YC+N+G+E Sbjct: 99 LASFG----------LTDDDLDEAFTL--TNFKGGGQ--MRLRDIVEAVKDTYCSNVGVE 144 Query: 651 FMFI 662 +M + Sbjct: 145 YMHV 148 Score = 37.1 bits (82), Expect(2) = 3e-08 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 3/43 (6%) Frame = +3 Query: 102 SSSAYVETMYNAWLADPNSVHASWDAFFRN---ATNGAQPGAA 221 ++SA +E Y+ WL +P+SV +W AFF+ T G+ GAA Sbjct: 9 ANSAILEQTYSQWLDNPDSVDPTWRAFFQGFTLGTTGSPIGAA 51 >UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=2; Cystobacterineae|Rep: 2-oxoglutarate dehydrogenase, E1 component - Myxococcus xanthus (strain DK 1622) Length = 963 Score = 60.1 bits (139), Expect = 7e-08 Identities = 52/197 (26%), Positives = 89/197 (45%), Gaps = 6/197 (3%) Frame = +3 Query: 84 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQP-GAAYTPPPNLAPY--- 251 + FL+G++ ++E +Y +L DP SV ASW F + +P + P AP Sbjct: 6 DTFLSGANIDFIEGLYARYLEDPASVDASWREVFDRSNGAGRPIFSTRLLEPVAAPAAAK 65 Query: 252 --NKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLG 425 K P + P+ P + G + + I V +I +++ RGHL A+LDPL Sbjct: 66 GGGKGAAPKAQVAPAPQPAPVAAPGQSVQD--ISLQARVDHVIFAFRLRGHLRAKLDPL- 122 Query: 426 ISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREI 605 G P + A + + F +A+ ++ + + GE+ + L E+ Sbjct: 123 ---GRPRPAL-------AHVADVALVDDSHFTDAEAQQL--VETNGVFGEQR--VRLTEL 168 Query: 606 LNRLEQAYCNNIGIEFM 656 L RL + Y + IG+E+M Sbjct: 169 LARLRRTYTDTIGVEYM 185 >UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1 component family protein; n=1; Tetrahymena thermophila SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component family protein - Tetrahymena thermophila SB210 Length = 1054 Score = 59.7 bits (138), Expect = 9e-08 Identities = 34/113 (30%), Positives = 57/113 (50%) Frame = +3 Query: 84 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNE 263 + FL G ++ +VE ++ W DP SV SW+ +F+N G +P A++ PP+ Sbjct: 36 DSFLAGCNAEFVEGLFERWAEDPTSVGPSWNNYFKNLVRGVEPEYAFSLPPS-------- 87 Query: 264 VPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPL 422 LT + A + I+ D+L + ++ +Y+ RGH +A LDPL Sbjct: 88 -DLTKAIH--------MAPDHAMKFIVSDNLKARLLVDAYRIRGHEIADLDPL 131 >UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=16; cellular organisms|Rep: 2-oxoglutarate dehydrogenase, E1 component - Robiginitalea biformata HTCC2501 Length = 940 Score = 58.8 bits (136), Expect = 2e-07 Identities = 54/198 (27%), Positives = 89/198 (44%) Frame = +3 Query: 90 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVP 269 FLN + +A+ +Y+ +L P+SV SW AFF+ G + A Sbjct: 6 FLNAAHTAFFSDLYDRYLTHPDSVEPSWRAFFQGFDFGMESALEEIGIDAEA-------- 57 Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449 +V ++GG A P++ K V +I Y+SRGHL Q +P+ Sbjct: 58 --GVVRTAGGD---EAAMPLSLK---KEFQVVRLIDGYRSRGHLFTQTNPVR-------- 101 Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629 R + I ++ +E+D+++VF IG LREI++ L + Y Sbjct: 102 ------ERRTYTPSLEI-ENFGLEESDLEKVFSAGDIIGIGPST----LREIIDHLTRIY 150 Query: 630 CNNIGIEFMFINSLETMQ 683 C+ IG+E+M+I S E ++ Sbjct: 151 CDAIGVEYMYIRSPERVE 168 >UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 component, putative; n=6; Trypanosomatidae|Rep: 2-oxoglutarate dehydrogenase E1 component, putative - Leishmania major Length = 979 Score = 57.6 bits (133), Expect = 4e-07 Identities = 49/197 (24%), Positives = 84/197 (42%), Gaps = 4/197 (2%) Frame = +3 Query: 84 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNE 263 + FL+GSS+ Y++ +Y W DP SV ASW F + +L YN Sbjct: 20 DSFLSGSSAMYMDGLYQQWKKDPASVDASWAELFSRS--------------DLGNYNHAL 65 Query: 264 VPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDP 443 + V +P+ S+ + ++ + D + +I +++ RGHL+AQ DPL D Sbjct: 66 LDTPICV-----LPAKSSDEAVVKQSLADCGRLIRMIHTFEDRGHLMAQTDPLNYVDTDV 120 Query: 444 VSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIG----EKEKALPLREILN 611 R + + F + D+DRV ++ +G L +R++ Sbjct: 121 TERTP---SRRYKEMVRLDLAYFGFSDKDLDRVVRVGFQNQMGGIYDTSSPQLTIRQLHE 177 Query: 612 RLEQAYCNNIGIEFMFI 662 L + YC IG E + + Sbjct: 178 LLTERYCGRIGFELVHL 194 >UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=4; Bacteria|Rep: Alpha-ketoglutarate dehydrogenase E1 - Rhodopirellula baltica Length = 969 Score = 54.4 bits (125), Expect = 3e-06 Identities = 61/214 (28%), Positives = 88/214 (41%), Gaps = 22/214 (10%) Frame = +3 Query: 93 LNGSSSAYVETMYNAWLADPNSVHASWDAFFRN------ATNGAQPGAAYTPPPNLAPYN 254 +N S Y++ +Y ++ DP+SV +W +F A A P A+ T A N Sbjct: 14 MNSYSLDYIDDLYVQYVRDPSSVSETWRQYFEQFLVGAGARTNAAPAASQTASQGDASAN 73 Query: 255 KNEVPLTSLV--------PSSGGMPSISAGSPINEKIIDDHL-------AVQAIIRSYQS 389 S+V P S S GS ++ +D L V ++R Y+ Sbjct: 74 GKTSGARSVVAPAFASGQPGSAEDTSERPGST-GDQNVDQALWLARIQDRVDQLVREYRV 132 Query: 390 RGHLVAQLDPLGISTGD-PVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTF 566 RGHLVA LDPLG+ P S HG + D+ R P + Sbjct: 133 RGHLVATLDPLGLFEHTCPELSPRSHG----------------LSKQDLAR----PFDSS 172 Query: 567 IGEKEKALPLREILNRLEQAYCNNIGIEFMFINS 668 I E L ILN+L+ YC +IG +FM I++ Sbjct: 173 ILENVSGSTLDVILNKLQSTYCRSIGAQFMHIDN 206 >UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E1 component; n=7; Bacteria|Rep: 2-oxoglutarate dehydrogenase complex, E1 component - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 942 Score = 52.8 bits (121), Expect = 1e-05 Identities = 52/192 (27%), Positives = 87/192 (45%) Frame = +3 Query: 90 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVP 269 +L G+++ ++E +Y +LADP +V +W +F +A AQ GAA + Sbjct: 10 YLFGANAPFIEELYENYLADPAAVPEAWRGYF-DALQ-AQAGAAVRD----VAHGPVIAA 63 Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449 T L G + +++AG ++ + +I +Y+ G+ A LDPL + ++ Sbjct: 64 FTELA-KRGPVRTVTAGGDDRRQV-----STLQLINAYRFLGNRWANLDPLKRTERPQLA 117 Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629 + F EAD+++ F + S F G LREIL L Q Y Sbjct: 118 ELE--------------PSFYGFTEADLNQSFNVGS--FHGFSADHATLREILEALRQTY 161 Query: 630 CNNIGIEFMFIN 665 C +IG E+M I+ Sbjct: 162 CGSIGSEYMHIS 173 >UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Brucella melitensis Length = 1004 Score = 52.0 bits (119), Expect = 2e-05 Identities = 68/227 (29%), Positives = 103/227 (45%), Gaps = 24/227 (10%) Frame = +3 Query: 57 NRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFF-----------RNA--- 194 +R A FL G ++ Y+E +Y + DPNSV W FF +NA Sbjct: 9 DRANDVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGP 68 Query: 195 --TNGAQPGAAYTPPPNLAPYNKNEVP--LTSLVPSSG--GMPSISAGSPINEKIIDDHL 356 T P AA + N EV +T + G +AG+P+ + I Sbjct: 69 SWTRKNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAA 128 Query: 357 --AVQAI--IRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDE 524 +V+AI IR+Y+ RGHL A LDPLG++ D+ NE + ++ F Sbjct: 129 RDSVRAIMMIRAYRMRGHLHANLDPLGLAE----KPNDY--------NE-LEPENYGFTP 175 Query: 525 ADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFIN 665 AD +R K+ +G + +P E+L+ L++ YC IG+EFM I+ Sbjct: 176 ADYNR--KIFIDNVLGLEYATVP--EMLDILKRTYCGAIGVEFMHIS 218 >UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit; n=2; Anaeromyxobacter|Rep: 2-oxoglutarate dehydrogenase, E1 subunit - Anaeromyxobacter sp. Fw109-5 Length = 940 Score = 50.4 bits (115), Expect = 6e-05 Identities = 51/196 (26%), Positives = 84/196 (42%) Frame = +3 Query: 87 PFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEV 266 P + S+ ++VE +Y WLADP++V W +F + A PG A P AP Sbjct: 11 PAPSASNLSFVEDLYYEWLADPSAVDERWRRYFESVP--ATPGTAKAPEA-FAPRR---- 63 Query: 267 PLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPV 446 P + P+ G + SA + K V ++ +Y+ GHL A LDPL ++ Sbjct: 64 PDGGVAPAPGAALA-SADAAFQAK-------VDRLVTAYREYGHLRADLDPLALTRRAER 115 Query: 447 SSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQA 626 S G +A+++R P G ++ LR ++ RLE+ Sbjct: 116 FSPATFG----------------LSDAELER----PCADPEGRGDRT--LRGLVARLEET 153 Query: 627 YCNNIGIEFMFINSLE 674 YC +G+E ++ + Sbjct: 154 YCRTLGVELAHMHDAD 169 >UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component; n=4; Bacteroidetes|Rep: Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 946 Score = 49.6 bits (113), Expect = 1e-04 Identities = 52/208 (25%), Positives = 89/208 (42%) Frame = +3 Query: 57 NRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPP 236 NR KS+ +++ + +YV+ MY ++ DP+SV +W FF Q Sbjct: 5 NRKKSTMDNYSYVSNAEISYVDEMYQSYRKDPSSVDETWQKFFEGYNFSLQKYG------ 58 Query: 237 NLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLD 416 N ++ PS G+ ++ A SP + + + V +I +Y+SRGHL ++ + Sbjct: 59 EKGATNGG----SAEAPSGNGVAAV-ASSPAT-TVSEKEVRVHYLIHAYRSRGHLRSKTN 112 Query: 417 PLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPL 596 P+ R + +AD+D VF+ + IG A L Sbjct: 113 PV---------------RERKDRKPLLELTDFGLTDADLDVVFEAGNEIGIG----AASL 153 Query: 597 REILNRLEQAYCNNIGIEFMFINSLETM 680 R+I+ L+ Y IG E+M+I E + Sbjct: 154 RKIVETLKFIYEGAIGFEYMYIRKPEKL 181 >UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=4; Leptospira|Rep: 2-oxoglutarate dehydrogenase E1 component - Leptospira interrogans Length = 920 Score = 48.8 bits (111), Expect = 2e-04 Identities = 57/196 (29%), Positives = 85/196 (43%), Gaps = 2/196 (1%) Frame = +3 Query: 93 LNGSSSAYVETMYNAWLADPNSVHASWDAFFRNA-TNGAQPGAAYTPPPNLAPYNKNEVP 269 L G + A +E +YN + +P ++ W +FF+ TNG G+ YT N Sbjct: 9 LYGENGALLEELYNQYKLNPETLDKEWKSFFQEVDTNGLANGSGYTNG------NGKSAV 62 Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449 TS + SI IN ++ +Y+ +GHL A+LDPLGI + Sbjct: 63 ATSFTDAQAA--SIREMGIIN------------LLNAYRRQGHLAAKLDPLGIQKPN--- 105 Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629 R F + + H AD+D V + S T +G + L EI++ E+ Y Sbjct: 106 --------RTFIDS---KLH-NISPADIDTV--VDSET-LGR----VKLAEIVDLYEKVY 146 Query: 630 CNNIGIE-FMFINSLE 674 CN IG E F +N E Sbjct: 147 CNTIGAEHFYLVNDEE 162 >UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate dehydrogenase E1 component - Blochmannia floridanus Length = 970 Score = 48.0 bits (109), Expect = 3e-04 Identities = 46/198 (23%), Positives = 86/198 (43%), Gaps = 7/198 (3%) Frame = +3 Query: 90 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFR-------NATNGAQPGAAYTPPPNLAP 248 FL ++ +Y++ +Y +L +P+S+ SW F+ N ++ P L+ Sbjct: 14 FLTKNNQSYIDQIYEFFLKNPHSIDISWINIFKEWDIEEKNQNQSIINKQLHSTSPLLSE 73 Query: 249 YNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGI 428 Y+K + S + + EK I+ +Q +I S++ GH + LDPLG+ Sbjct: 74 YDKQDNSYKSYISTDID----------KEKTINISKILQ-LIHSFRKYGHQYSILDPLGL 122 Query: 429 STGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREIL 608 + + N + ++ +F + D+ + F T +G + + L I Sbjct: 123 T-------------INTVKNSFLELKYYKFLDKDVLQQF---DTNLLGMNKGIITLNSIY 166 Query: 609 NRLEQAYCNNIGIEFMFI 662 L++ YC IGIE+M I Sbjct: 167 KFLKKTYCGTIGIEYMHI 184 >UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1; Plesiocystis pacifica SIR-1|Rep: Alpha-ketoglutarate decarboxylase - Plesiocystis pacifica SIR-1 Length = 927 Score = 47.6 bits (108), Expect = 4e-04 Identities = 52/191 (27%), Positives = 72/191 (37%) Frame = +3 Query: 81 AEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKN 260 AE L+ + A++E +Y A+ ADPNSV W A Sbjct: 3 AEAALSVHNLAFLEALYEAYEADPNSVDPQWIPLLEEGRASA------------------ 44 Query: 261 EVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGD 440 +S SS + S GS E + V +I +Y+ GH+ A +DPLG Sbjct: 45 ----SSSSESSSRLHSAEPGSSAEEITLQTQ--VDNLIEAYRLHGHIGADIDPLGRPRST 98 Query: 441 PVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLE 620 + D H E MDR F T KA LREI+ RL Sbjct: 99 DATELD--------------PAHYGLGEQHMDREFGTAGLT----PHKA-SLREIIERLR 139 Query: 621 QAYCNNIGIEF 653 YC ++G+E+ Sbjct: 140 NTYCRHVGVEY 150 >UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=1; Blastopirellula marina DSM 3645|Rep: Alpha-ketoglutarate dehydrogenase E1 - Blastopirellula marina DSM 3645 Length = 929 Score = 46.8 bits (106), Expect = 7e-04 Identities = 50/189 (26%), Positives = 79/189 (41%), Gaps = 4/189 (2%) Frame = +3 Query: 111 AYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAP--YNKNEVPLTSLV 284 AY + +A+ DPNSV W +F A+T NLAP + T Sbjct: 2 AYAAELLDAYREDPNSVPDDWREWFGKLPQANGDAEAFT---NLAPPITTSSMFNPTGAP 58 Query: 285 PSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGD-PVSSADW 461 + G + SAG V +I ++++ GHL ++LDPLG++T P S D Sbjct: 59 VAVNGDHAASAGDAAVGADALLQFCVDRMITAFRAYGHLHSRLDPLGLTTTPAPPLSPD- 117 Query: 462 HGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKAL-PLREILNRLEQAYCNN 638 E+D+DR S + E L +RE+ R+++ YC + Sbjct: 118 ---------------QFNIKESDLDR-----SVYVDRDGETILTTVRELFERMQRVYCGD 157 Query: 639 IGIEFMFIN 665 +GI+ I+ Sbjct: 158 VGIQLQHID 166 >UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=3; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1 component - Salinibacter ruber (strain DSM 13855) Length = 1243 Score = 46.0 bits (104), Expect = 0.001 Identities = 41/138 (29%), Positives = 65/138 (47%), Gaps = 1/138 (0%) Frame = +3 Query: 264 VPLTSLVPSSGGMPSISAGSPINE-KIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGD 440 VP ++ P + P +E + + AV +IR+Y+ RGHL A ++PLG Sbjct: 354 VPYQPFRMATDSTPQLGRSRPQDELDMTEKQAAVLQLIRAYRVRGHLQADINPLGY---- 409 Query: 441 PVSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLE 620 +W +E + D+DR F T +G ++K LPLREIL+ L Sbjct: 410 -----EWQ------YHEELDPATYGLTVWDLDREF---ITGGLGGEDK-LPLREILSILR 454 Query: 621 QAYCNNIGIEFMFINSLE 674 ++Y + +G FM I+ E Sbjct: 455 KSYTSKVGTAFMHISDPE 472 >UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 component, putative; n=2; Theileria|Rep: 2-oxoglutarate dehydrogenase e1 component, putative - Theileria parva Length = 1030 Score = 46.0 bits (104), Expect = 0.001 Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 4/197 (2%) Frame = +3 Query: 96 NGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPP---NLA-PYNKNE 263 +G S Y+E +Y + +P + SW +F + + G YT P L YN Sbjct: 19 HGESLNYLEYLYYVYRTNPEHLQPSWQNYF----SLLEQGKTYTLPQIDRKLGHKYNGFA 74 Query: 264 VPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDP 443 PL +S ++ S N + + L + + +Y++ GHLV+ LDPL + P Sbjct: 75 GPLAGNQTTSQATELLAKVS--NGVVGLEVLKLNELASAYRTFGHLVSNLDPLKLPKEVP 132 Query: 444 VSSADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQ 623 + + ++ + ++ F++ D+ + K+P+ G + E+ +L++ Sbjct: 133 -----FFRNIDGIYDKLNVNKY--FNKDDLAK--KIPNLGIGGVFNMTGTVEELAEKLKE 183 Query: 624 AYCNNIGIEFMFINSLE 674 YC NI EF I + E Sbjct: 184 RYCGNISFEFGHIANSE 200 >UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=45; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1 component - Corynebacterium glutamicum (Brevibacterium flavum) Length = 1257 Score = 45.6 bits (103), Expect = 0.002 Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 1/108 (0%) Frame = +3 Query: 342 IDDHLAVQAIIRSYQSRGHLVAQLDPLG-ISTGDPVSSADWHGGMRAFANEAVIRQHVRF 518 +D + V +I +Y+SRGHL+A +PL + G PV H + + I Sbjct: 402 VDKNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMPVPD---HRDLDIETHNLTI------ 452 Query: 519 DEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFI 662 D+DR F + G KE + LRE+L+RL AY +G E+ I Sbjct: 453 --WDLDRTFNVGG---FGGKE-TMTLREVLSRLRAAYTLKVGSEYTHI 494 >UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=8; Deltaproteobacteria|Rep: 2-oxoglutarate dehydrogenase, E1 component - Geobacter sulfurreducens Length = 894 Score = 45.2 bits (102), Expect = 0.002 Identities = 20/52 (38%), Positives = 28/52 (53%) Frame = +3 Query: 90 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLA 245 F G+ ++E+++ +W ADP SV A W AFF G +A P P LA Sbjct: 3 FAAGADPEFIESLFQSWQADPASVSAEWRAFFTGYELGRGEPSAECPTPELA 54 Score = 43.2 bits (97), Expect = 0.008 Identities = 37/122 (30%), Positives = 58/122 (47%) Frame = +3 Query: 297 GMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMR 476 G PS +P ++ AV ++I Y+ GHL+A DPL P Sbjct: 42 GEPSAECPTP---ELAAKQSAVDSLIYRYRDLGHLLACTDPLS-----PCK--------- 84 Query: 477 AFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFM 656 + + + D++D+DR F+ + F+ K +A LREIL L + YC ++G+EFM Sbjct: 85 -LEHPLLALEQYDLDQSDLDRTFR--ARRFL--KSEAT-LREILATLRETYCRSVGVEFM 138 Query: 657 FI 662 I Sbjct: 139 HI 140 >UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=15; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1 component - Deinococcus radiodurans Length = 956 Score = 44.4 bits (100), Expect = 0.004 Identities = 47/195 (24%), Positives = 89/195 (45%), Gaps = 3/195 (1%) Frame = +3 Query: 99 GSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVPLTS 278 G ++A++E +Y ++L DP+SV A W ++F GAQ ++ P+T Sbjct: 15 GGNAAFIEGLYESYLQDPSSVGAEWRSYFDGLRGGAQERVHSEVQQRFYELGQHRGPVT- 73 Query: 279 LVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPL---GISTGDPVS 449 V +GG ++G+ A A++ +Y+ GH+ A+ +PL G+ T P Sbjct: 74 -VQVTGG----ASGA---------QQAAGALVTAYRVYGHISARNNPLKLRGVPT-VPEL 118 Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629 + +++G EAD+ ++ + F G LR+++ +L+ Y Sbjct: 119 TPEFYG----------------LSEADLSE--QVQDSPFSG------TLRDVIAQLQDTY 154 Query: 630 CNNIGIEFMFINSLE 674 C IG E+ ++ + E Sbjct: 155 CGAIGFEYNYLPANE 169 >UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1; Lentisphaera araneosa HTCC2155|Rep: Alpha-ketoglutarate decarboxylase - Lentisphaera araneosa HTCC2155 Length = 913 Score = 44.4 bits (100), Expect = 0.004 Identities = 27/114 (23%), Positives = 55/114 (48%) Frame = +3 Query: 342 IDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFD 521 ++ + + +I +Y+SRGHL+++ +P+ R + + D Sbjct: 56 VEKEVKIMKLINAYRSRGHLISKTNPIR---------------PRRLHQADLTLDYFGLD 100 Query: 522 EADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLETMQ 683 EAD++ F + +G + L++I++ LE YC++IG+E+ + S E Q Sbjct: 101 EADLEEEFDVGHEIRLGRAK----LKDIISHLEDTYCSSIGVEYRYSQSSEMRQ 150 Score = 35.9 bits (79), Expect = 1.3 Identities = 14/31 (45%), Positives = 20/31 (64%) Frame = +3 Query: 96 NGSSSAYVETMYNAWLADPNSVHASWDAFFR 188 + ++ AY+E M + DPNSV ASW FF+ Sbjct: 8 DNANPAYIEMMLQKFKTDPNSVDASWQQFFQ 38 >UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit; n=2; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1 subunit - Solibacter usitatus (strain Ellin6076) Length = 1220 Score = 43.2 bits (97), Expect = 0.008 Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 3/123 (2%) Frame = +3 Query: 303 PSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAF 482 P++ S I + +I +Y+ RGHL+A LDPLG S H + Sbjct: 329 PTLPGVSAARYAEIAKEAGIIQMINAYRVRGHLIADLDPLG-------SEPSLHAELDPE 381 Query: 483 ANEAVIRQHVRFDEADMDRVFKLPST-TFIGE-KEKALP-LREILNRLEQAYCNNIGIEF 653 I D+DR F S IGE K+L LREIL L Q YC IG E+ Sbjct: 382 TYGLTIW--------DLDREFLTGSLGEAIGEGAPKSLATLREILETLRQTYCGKIGCEY 433 Query: 654 MFI 662 M I Sbjct: 434 MNI 436 >UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=11; Francisella tularensis|Rep: 2-oxoglutarate dehydrogenase E1 component - Francisella tularensis subsp. tularensis (strain FSC 198) Length = 941 Score = 41.5 bits (93), Expect = 0.026 Identities = 29/110 (26%), Positives = 56/110 (50%) Frame = +3 Query: 345 DDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDE 524 D L +A++++Y+S G+ A +DPLG++ + S + + H E Sbjct: 92 DIGLKAKALVKAYRSYGYKSANIDPLGLTRFERDSDLE-------------LAAH-GLSE 137 Query: 525 ADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLE 674 D+ ++ L T KA+PL++++N+ + Y +NIG E+ +I + E Sbjct: 138 KDLTQLVNLGDFT----DNKAIPLQQVINKAKAIYESNIGYEYRYIGNKE 183 >UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 component , putative; n=1; Babesia bovis|Rep: 2-oxoglutarate dehydrogenase E1 component , putative - Babesia bovis Length = 891 Score = 41.5 bits (93), Expect = 0.026 Identities = 25/103 (24%), Positives = 48/103 (46%) Frame = +3 Query: 354 LAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADM 533 L + ++R+Y++ GH V+ LDPL + P +H + + + + H + D Sbjct: 22 LRLSELVRAYRTEGHCVSTLDPLDLPREPP-----FHRFIPSDVSTKLC--HTTYGLKDE 74 Query: 534 DRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFI 662 D LPS G + + E ++ L + YC + +EF+ + Sbjct: 75 DLGRPLPSGLIPGHMGSSSTVAECIDNLRRTYCGDFAVEFIHL 117 >UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=5; Enterobacteriaceae|Rep: 2-oxoglutarate dehydrogenase E1 component - Escherichia coli (strain UTI89 / UPEC) Length = 939 Score = 40.7 bits (91), Expect = 0.045 Identities = 31/123 (25%), Positives = 58/123 (47%) Frame = +3 Query: 306 SISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFA 485 S+S + ++ + AV +I +++++GHL A+LDPLG++ P G + Sbjct: 75 SVSGDNNVSGATLKKQAAVIQLINAWRTQGHLRAKLDPLGLN--PPADVPSLQPGFWGLS 132 Query: 486 NEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFIN 665 E ++++ S TF G +PL+++LN LEQA+ + E + Sbjct: 133 EEDLLQEF---------------SVTF-GAHTTQMPLKQLLNLLEQAWAGSQAYELAHLE 176 Query: 666 SLE 674 + E Sbjct: 177 NRE 179 >UniRef50_A5XEI0 Cluster: Oxoglutarate (Alpha-ketoglutarate) dehydrogenase; n=4; Euteleostomi|Rep: Oxoglutarate (Alpha-ketoglutarate) dehydrogenase - Homo sapiens (Human) Length = 65 Score = 39.1 bits (87), Expect = 0.14 Identities = 16/24 (66%), Positives = 21/24 (87%) Frame = +3 Query: 360 VQAIIRSYQSRGHLVAQLDPLGIS 431 VQ++IR+YQ RGH + +LDPLGIS Sbjct: 1 VQSLIRAYQVRGHHIVKLDPLGIS 24 >UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 1304 Score = 38.7 bits (86), Expect = 0.18 Identities = 33/105 (31%), Positives = 47/105 (44%) Frame = +3 Query: 360 VQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADMDR 539 + +I +Y+SRGHL A DPL R + + D+DR Sbjct: 440 IAELIHAYRSRGHLAADTDPLAY---------------RVRRHPDLDLSSYGLSVWDLDR 484 Query: 540 VFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLE 674 F P+ F G+ ++ L LR+IL RL Y +GIE+M I E Sbjct: 485 PF--PTGGF-GDSDQML-LRDILTRLHDTYTRTVGIEYMHIQDPE 525 >UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 component family protein; n=1; Tetrahymena thermophila SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component family protein - Tetrahymena thermophila SB210 Length = 992 Score = 37.9 bits (84), Expect = 0.32 Identities = 14/27 (51%), Positives = 18/27 (66%) Frame = +3 Query: 105 SSAYVETMYNAWLADPNSVHASWDAFF 185 S+ YVE M++ W DPNSVH W +F Sbjct: 37 SNLYVEQMFDQWSKDPNSVHEMWRDYF 63 >UniRef50_Q2JFB9 Cluster: Putative uncharacterized protein; n=1; Frankia sp. CcI3|Rep: Putative uncharacterized protein - Frankia sp. (strain CcI3) Length = 900 Score = 36.7 bits (81), Expect = 0.73 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 3/64 (4%) Frame = +3 Query: 144 ADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYN---KNEVPLTSLVPSSGGMPSIS 314 ADP V +WD G PG + TPP P + P+ S P P +S Sbjct: 11 ADPFDVTTTWDGPAPGPAGGRPPGISVTPPAPAGPSTPAVSSAAPVASPAPPVPRGPRVS 70 Query: 315 AGSP 326 AG P Sbjct: 71 AGPP 74 >UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=17; Staphylococcus|Rep: 2-oxoglutarate dehydrogenase E1 component - Staphylococcus aureus Length = 932 Score = 36.3 bits (80), Expect = 0.97 Identities = 14/39 (35%), Positives = 24/39 (61%) Frame = +1 Query: 685 WIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKN 801 W+++R+E P +N ++KR + +L GFE +L KN Sbjct: 164 WLKRRIETPYKVTLNNNEKRALFKQLAYVEGFEKYLHKN 202 >UniRef50_Q8UDS8 Cluster: Short chain dehydrogenase; n=1; Agrobacterium tumefaciens str. C58|Rep: Short chain dehydrogenase - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 249 Score = 35.9 bits (79), Expect = 1.3 Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 3/106 (2%) Frame = +3 Query: 171 WDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDD 350 WD A GA Y PP L + V +S V +S G+P +SA ++ Sbjct: 108 WDHVLNVNLTSAFLGARYQIPPMLKRGGGSIVFTSSFVGTSAGIPGMSAYGTAKAALMG- 166 Query: 351 HLAVQAIIRSYQSRGHLVAQLDPLGIST---GDPVSSADWHGGMRA 479 V+ I Y G L P G+ T GDP + +W G+ A Sbjct: 167 --LVKGITADYAINGIRANALLPGGVDTPAAGDP-AQKEWAAGLHA 209 >UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, putative; n=7; Trypanosomatidae|Rep: 2-oxoglutarate dehydrogenase subunit, putative - Trypanosoma brucei Length = 1008 Score = 35.5 bits (78), Expect = 1.7 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 4/105 (3%) Frame = +3 Query: 354 LAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVRFDEADM 533 + + ++ +Y+ GH A+++PL S D R N + + F + D+ Sbjct: 102 MGITWMVTAYERYGHHYAKVNPLR-------SEQDVESDRRDLLN--LHYSNFGFTDQDL 152 Query: 534 DRVFKLPS----TTFIGEKEKALPLREILNRLEQAYCNNIGIEFM 656 +VF + GE K L++I+ +L+ YC +IG EF+ Sbjct: 153 TKVFPVDIGGGLKEAFGENVKEATLQQIVEKLQMMYCGSIGFEFL 197 >UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=4; Enterobacteriaceae|Rep: 2-oxoglutarate dehydrogenase E1 component - Buchnera aphidicola subsp. Schizaphis graminum Length = 923 Score = 35.5 bits (78), Expect = 1.7 Identities = 39/196 (19%), Positives = 81/196 (41%), Gaps = 1/196 (0%) Frame = +3 Query: 90 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVP 269 +L+G++ Y+E +Y ++L +P SV +W F + L+ KN + Sbjct: 14 WLSGNNQNYIEKIYESYLINPKSVDITWQDKFSD----------------LSKKRKNILK 57 Query: 270 LTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVS 449 V + I ++I++ + II +++ +G+ + +DPL ++ Sbjct: 58 EEKFVYKNNSFKEIKIDK---QEILEKK--INYIINTFRKKGYKKSLIDPLKLNEQKKYK 112 Query: 450 SADWHGGMRAFANEAVIRQHVRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAY 629 + F E ++ + K+ F + + +R++ +L Y Sbjct: 113 YLE--------------PTFYHFSEDELKKTVKID---FKNSSQYEIKIRDLYEQLNNKY 155 Query: 630 CNNIGIEFMFI-NSLE 674 C +IG E+M+I NS E Sbjct: 156 CGSIGFEYMYIENSFE 171 >UniRef50_Q02C37 Cluster: Putative uncharacterized protein; n=1; Solibacter usitatus Ellin6076|Rep: Putative uncharacterized protein - Solibacter usitatus (strain Ellin6076) Length = 365 Score = 35.1 bits (77), Expect = 2.2 Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 1/59 (1%) Frame = +3 Query: 393 GHLVAQLDPLGISTGDPVSSADWHGGMRAF-ANEAVIRQHVRFDEADMDRVFKLPSTTF 566 G L L+ LG A H GMR A +A + HV E D+DR F LP T+ Sbjct: 69 GELAFFLESLGYQVVAADHPAYNHNGMRGIRALKAALGSHVEIHEIDVDRPFTLPHDTY 127 >UniRef50_UPI0000F2D68A Cluster: PREDICTED: hypothetical protein; n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical protein - Monodelphis domestica Length = 522 Score = 34.7 bits (76), Expect = 3.0 Identities = 18/41 (43%), Positives = 24/41 (58%) Frame = -1 Query: 553 GSLNTLSMSASSNLTCCLMTASLAKARMPPCQSALDTGSPV 431 G L+ L S +T CL+TA AKA+ PP ALD G+ + Sbjct: 177 GKLDFLVFDYLSEITMCLLTA--AKAKSPPISRALDLGADI 215 >UniRef50_Q0RQH6 Cluster: Putative LuxR-family transcriptional regulator; n=2; Bacteria|Rep: Putative LuxR-family transcriptional regulator - Frankia alni (strain ACN14a) Length = 1436 Score = 34.7 bits (76), Expect = 3.0 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Frame = +3 Query: 201 GAQPGAAYTPPPNLA-PYNKNEVPLTSLVPSSGGMPSISAGSP 326 G++P Y PPP + P V + P GG P++ AGSP Sbjct: 1263 GSRPSGGYAPPPGRSEPERGTPVVGSPKAPGVGGPPAVGAGSP 1305 >UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 component; n=1; Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate dehydrogenase, E1 component - Dichelobacter nodosus (strain VCS1703A) Length = 917 Score = 34.7 bits (76), Expect = 3.0 Identities = 30/128 (23%), Positives = 55/128 (42%) Frame = +3 Query: 69 SSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAP 248 + TA + + ++AY+E +Y +L P+SV W +F + P A Sbjct: 2 TKTAQKSAYSSENAAYLEQLYEHYLTQPDSVAPQWQNYFERLNQQSSP----------AF 51 Query: 249 YNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGI 428 +E T+ S+ + +K + V +IR+Y+ RGH A LDPL Sbjct: 52 MTHSEHAATA---------SVQENAAHGQK----QIGVLNLIRAYRVRGHRHAHLDPLTN 98 Query: 429 STGDPVSS 452 + + +++ Sbjct: 99 APSEDIAA 106 >UniRef50_A0LLC1 Cluster: Putative uncharacterized protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Putative uncharacterized protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 392 Score = 34.7 bits (76), Expect = 3.0 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Frame = +3 Query: 486 NEAVIRQH-VRFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQA 626 N+ +I H +DEAD R + +GE E ALPL+ I ++EQ+ Sbjct: 92 NQTIIDSHPTEWDEADFRRNWSQFLQMLVGENENALPLKRIQYQVEQS 139 >UniRef50_A5DZM2 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 807 Score = 34.3 bits (75), Expect = 3.9 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 3/103 (2%) Frame = +3 Query: 27 PQTAAVSVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWD---AFFRNAT 197 PQT+ + NA + S +PF+ S + T + A A+ NS + FF + + Sbjct: 653 PQTSQGAQNALASQGSQVPQPFIPQSQVPFQATQF-ATPANTNSFNGPGYYPIPFFYHPS 711 Query: 198 NGAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSP 326 A Y PPP L P++ P T L P I+ P Sbjct: 712 ASGIAYATYQPPPALLPHHAYPAPPT-LYPMKNFKQPIAVAQP 753 >UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1; Bacillus sp. B14905|Rep: Alpha-ketoglutarate decarboxylase - Bacillus sp. B14905 Length = 670 Score = 33.9 bits (74), Expect = 5.2 Identities = 15/40 (37%), Positives = 27/40 (67%), Gaps = 1/40 (2%) Frame = +1 Query: 682 NWIRQRMEPPNVTK-MNADQKRLILARLTRSTGFENFLAK 798 NWI+ ++E + + +++D+K+ +L RLTR FE F+ K Sbjct: 181 NWIQAQIESGSFQQALSSDEKKALLDRLTRVENFEKFIHK 220 >UniRef50_A7QD53 Cluster: Chromosome undetermined scaffold_80, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome undetermined scaffold_80, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 648 Score = 33.9 bits (74), Expect = 5.2 Identities = 17/56 (30%), Positives = 32/56 (57%) Frame = +3 Query: 513 RFDEADMDRVFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLETM 680 +F+E++ + L ST F GE ++ + + L L+ ++CN G +FI SL+ + Sbjct: 246 KFNESNSILLLDLSSTNFSGELPSSISILKSLESLDLSHCNFSGSIPLFIASLDNL 301 >UniRef50_Q4QJD5 Cluster: Putative uncharacterized protein; n=2; Leishmania|Rep: Putative uncharacterized protein - Leishmania major Length = 2544 Score = 33.9 bits (74), Expect = 5.2 Identities = 25/110 (22%), Positives = 49/110 (44%), Gaps = 1/110 (0%) Frame = +3 Query: 141 LADPNSVHASWDAFFRNATNGAQPGAAYTPP-PNLAPYNKNEVPLTSLVPSSGGMPSISA 317 +A+ +S + S + +Q GAA P P +K+ P+ + S+ P+ +A Sbjct: 2007 VAESSSSNRSASSVLSFHVEDSQEGAALQQPGPGSDGADKDHYPVAASGSSAAAAPA-AA 2065 Query: 318 GSPINEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTGDPVSSADWHG 467 P +++ A + + + A+ PL I G+P++ +D HG Sbjct: 2066 AQPSSDESTSPVTAAVDSLATPSTASPQAAEGRPLSIDRGEPITDSDRHG 2115 >UniRef50_UPI0000DD7C6C Cluster: PREDICTED: hypothetical protein; n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein - Homo sapiens Length = 241 Score = 33.5 bits (73), Expect = 6.8 Identities = 13/24 (54%), Positives = 16/24 (66%) Frame = +3 Query: 162 HASWDAFFRNATNGAQPGAAYTPP 233 HA W AFFR +++ PG A TPP Sbjct: 47 HAGWTAFFRGSSSVRVPGPASTPP 70 >UniRef50_Q395C1 Cluster: Rhs family protein; n=6; Burkholderia|Rep: Rhs family protein - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 1429 Score = 33.5 bits (73), Expect = 6.8 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Frame = +3 Query: 273 TSLVPSSGGMPSISAGSP-INEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTG 437 TS++ +G + IS + E+I D A Q R Y ++GHL ++ DPLG TG Sbjct: 551 TSIIDPAGQVTRISYNDRNLPEQITDP--AGQVWQRGYDAQGHLTSETDPLGNVTG 604 >UniRef50_A4U1B6 Cluster: Secreted protein; n=1; Magnetospirillum gryphiswaldense|Rep: Secreted protein - Magnetospirillum gryphiswaldense Length = 357 Score = 33.5 bits (73), Expect = 6.8 Identities = 32/139 (23%), Positives = 59/139 (42%), Gaps = 9/139 (6%) Frame = +3 Query: 12 WLLNKPQTAAVSVNANRLKSSTAAEPFLNGSSSAYVETMYNAW----LADPNSVHASWDA 179 W L Q +A+ +A +++S A + +A V A LA+PN +D Sbjct: 200 WFLR--QNSALYDSAKAIRASLAQSAIRADNHAAPVNAADGATAAVALAEPNIPFDEYDR 257 Query: 180 FFRNATN-----GAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKII 344 F T+ GAQ A+ P P ++ N+ + G+P ++ G+ + ++ Sbjct: 258 LFNQFTDAVLASGAQLIVAFLPGPGVSQTNERIGEFIDTLSRQRGLPFLNLGTALADRSA 317 Query: 345 DDHLAVQAIIRSYQSRGHL 401 D+ ++ +Y S HL Sbjct: 318 DEIYLMRQNDPTYPSDIHL 336 >UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase, E1 subunit; n=3; cellular organisms|Rep: Predicted 2-oxoglutarate dehydrogenase, E1 subunit - Ostreococcus tauri Length = 1210 Score = 33.5 bits (73), Expect = 6.8 Identities = 16/36 (44%), Positives = 22/36 (61%) Frame = +3 Query: 330 NEKIIDDHLAVQAIIRSYQSRGHLVAQLDPLGISTG 437 +E D L + + R+ ++RGHL A LDPLG S G Sbjct: 58 SEAASHDALRLIELARAVRARGHLTASLDPLGRSLG 93 >UniRef50_Q5K6W4 Cluster: Putative uncharacterized protein; n=1; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 394 Score = 33.5 bits (73), Expect = 6.8 Identities = 23/85 (27%), Positives = 46/85 (54%) Frame = +3 Query: 117 VETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSG 296 + T+YN+ + D + + + T+ +QP A+++ PP+++ N+ PL PS Sbjct: 183 IHTIYNS-IEDQDIYTPIFVQWLPRITHPSQPSASFSHPPDMS--NRKGAPL----PSLS 235 Query: 297 GMPSISAGSPINEKIIDDHLAVQAI 371 G+ + S+ S N+ + +D LA + I Sbjct: 236 GLCNHSSPSVDNQFLSEDFLAPEVI 260 >UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 component; n=14; Rickettsia|Rep: 2-oxoglutarate dehydrogenase E1 component - Rickettsia felis (Rickettsia azadi) Length = 977 Score = 33.5 bits (73), Expect = 6.8 Identities = 12/32 (37%), Positives = 21/32 (65%) Frame = +3 Query: 90 FLNGSSSAYVETMYNAWLADPNSVHASWDAFF 185 +L G ++ +V+ +Y +LA+P SV +W FF Sbjct: 10 YLFGGNAVFVDELYRQYLANPASVDQTWQEFF 41 >UniRef50_Q13118 Cluster: Krueppel-like factor 10; n=35; Amniota|Rep: Krueppel-like factor 10 - Homo sapiens (Human) Length = 480 Score = 33.5 bits (73), Expect = 6.8 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 2/105 (1%) Frame = +3 Query: 207 QPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSP-INEKIIDDHLAVQ-AIIRS 380 QP + PP ++P N L+ + P+ G PS + +P I+ I H+ ++ Sbjct: 323 QPVVQSSKPPVVSP---NGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKT 379 Query: 381 YQSRGHLVAQLDPLGISTGDPVSSADWHGGMRAFANEAVIRQHVR 515 Y HL A TG+ S W G R FA + +H R Sbjct: 380 YFKSSHLKAHTRT---HTGEKPFSCSWKGCERRFARSDELSRHRR 421 >UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; n=23; Coelomata|Rep: Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 2154 Score = 33.1 bits (72), Expect = 9.0 Identities = 12/46 (26%), Positives = 21/46 (45%) Frame = +3 Query: 99 GSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPP 236 G+S Y+ + + + DP ++ WD F NA + G + P Sbjct: 288 GTSRCYITSQNHGFAVDPETLPKDWDVLFTNANDQTSEGIVHNHKP 333 >UniRef50_Q2JGL1 Cluster: Rieske (2Fe-2S) protein; n=7; Actinomycetales|Rep: Rieske (2Fe-2S) protein - Frankia sp. (strain CcI3) Length = 365 Score = 33.1 bits (72), Expect = 9.0 Identities = 16/32 (50%), Positives = 18/32 (56%) Frame = +2 Query: 317 RFPYKREDNRRSPRRAGYHQELPVEGSSCGAT 412 RF +RE RSP+ GY ELP GS C T Sbjct: 24 RFERERELVLRSPQLVGYRSELPAPGSYCTKT 55 >UniRef50_A1IAX2 Cluster: Outer membrane lipoprotein-sorting protein-like precursor; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Outer membrane lipoprotein-sorting protein-like precursor - Candidatus Desulfococcus oleovorans Hxd3 Length = 229 Score = 33.1 bits (72), Expect = 9.0 Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Frame = +3 Query: 588 LPLREILNRLEQAY-CNNIGIEFMFINSLETMQLDPTAHGA 707 LP+ EIL+R+E Y C+ +F ++L+ M + TA G+ Sbjct: 33 LPVEEILSRVEARYDCDTFAADFFQTSTLKAMDITDTAEGS 73 >UniRef50_Q8S6C0 Cluster: Putative uncharacterized protein OJ1004_D04.4; n=1; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein OJ1004_D04.4 - Oryza sativa subsp. japonica (Rice) Length = 503 Score = 33.1 bits (72), Expect = 9.0 Identities = 15/37 (40%), Positives = 21/37 (56%) Frame = +3 Query: 231 PPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKI 341 PP+ +P VP TS PS+ PS S+ SPI + + Sbjct: 345 PPSSSPVVPRSVPCTSAGPSTSAPPSSSSSSPIKKAL 381 >UniRef50_Q01A93 Cluster: Chromosome 04 contig 1, DNA sequence; n=3; Ostreococcus|Rep: Chromosome 04 contig 1, DNA sequence - Ostreococcus tauri Length = 334 Score = 33.1 bits (72), Expect = 9.0 Identities = 18/59 (30%), Positives = 27/59 (45%) Frame = +3 Query: 63 LKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPN 239 L +T AEP++ + V + WL++ ++ A W F N QPGA PN Sbjct: 248 LNETTDAEPYMTQAQRDKVREIAG-WLSESDAGKALWHVHFGNPAEEFQPGAPGALTPN 305 >UniRef50_Q55GQ4 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 567 Score = 33.1 bits (72), Expect = 9.0 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 8/85 (9%) Frame = +3 Query: 282 VPSSGGMPSISAGSP--INEKIIDDHLA----VQAIIRSYQSRGHLVAQLDPLGISTGDP 443 V SS S S+ SP + + I+DH++ +II +S+GH++ QL P P Sbjct: 34 VESSSSSSSTSSRSPSVVFKSYINDHISNNERYTSIINHIESKGHIIEQLHPYSSLPSSP 93 Query: 444 VSSADWH--GGMRAFANEAVIRQHV 512 + + G + +N +++ H+ Sbjct: 94 SNDIHYATIGSDKLLSNLPLLKDHI 118 >UniRef50_Q9UU85 Cluster: Protein kinase domain-containing protein ppk38; n=1; Schizosaccharomyces pombe|Rep: Protein kinase domain-containing protein ppk38 - Schizosaccharomyces pombe (Fission yeast) Length = 650 Score = 33.1 bits (72), Expect = 9.0 Identities = 33/148 (22%), Positives = 61/148 (41%), Gaps = 3/148 (2%) Frame = +3 Query: 24 KPQTAAVSVNANRLKSSTAAEPFLNGSSSAYVETM-YNAWLADPNSVHASWDAFFRNATN 200 KP + + N N + + + NG++S+ V Y ++ S F T Sbjct: 360 KPMASPMLPNVNSMPYLSNGDHNNNGNTSSPVSRFSYGQHTSNVPSTQKLPSNF--RVTQ 417 Query: 201 GAQPGAAYTPPPNLAPYNKNEVPLTSLVPSSGGMPSISAGSPINEKIIDDHLAVQAIIRS 380 GA P Y PPP + P K ++ T+ S+ + S E + + ++S Sbjct: 418 GAPPSHTYGPPPPVQP--KPKISPTTPRLSTLALADDMFSSTAKETVPTNEAVFTGDVKS 475 Query: 381 YQSRGHLVAQLDPLGIS--TGDPVSSAD 458 + S+ + + +PL S +G P +S + Sbjct: 476 FDSQESNIIESEPLSASNASGKPRTSVN 503 >UniRef50_Q4IER0 Cluster: Leucine carboxyl methyltransferase 2; n=1; Gibberella zeae|Rep: Leucine carboxyl methyltransferase 2 - Gibberella zeae (Fusarium graminearum) Length = 989 Score = 33.1 bits (72), Expect = 9.0 Identities = 19/88 (21%), Positives = 39/88 (44%) Frame = +3 Query: 45 SVNANRLKSSTAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAY 224 +++ ++L S+ E FLN ++ M+ + + + + FFR+ +G G Sbjct: 885 ALDTHQLASTNPHEAFLNPGDLLFIPAMWFHTASPVTDLSVAVNVFFRDLESGYSTGRDV 944 Query: 225 TPPPNLAPYNKNEVPLTSLVPSSGGMPS 308 +LA Y K ++ + S +PS Sbjct: 945 YGNRDLAAYEKGRQDISRITKSFDRLPS 972 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 878,546,051 Number of Sequences: 1657284 Number of extensions: 18567888 Number of successful extensions: 62304 Number of sequences better than 10.0: 78 Number of HSP's better than 10.0 without gapping: 58552 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 62203 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 74193458591 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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