Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP01_FL5_A24
(851 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q16J23 Cluster: Camp-specific 3,5-cyclic phosphodiester... 338 7e-92
UniRef50_UPI00015B4893 Cluster: PREDICTED: similar to camp-speci... 336 5e-91
UniRef50_UPI0000DB6B8B Cluster: PREDICTED: similar to phosphodie... 320 2e-86
UniRef50_Q13946 Cluster: High affinity cAMP-specific 3',5'-cycli... 249 6e-65
UniRef50_Q4RR95 Cluster: Chromosome 14 SCAF15003, whole genome s... 239 5e-62
UniRef50_UPI0000E7FF0E Cluster: PREDICTED: similar to cAMP phosp... 217 2e-55
UniRef50_UPI00015B5210 Cluster: PREDICTED: similar to ENSANGP000... 145 1e-33
UniRef50_Q9N2V9 Cluster: Probable 3',5'-cyclic phosphodiesterase... 137 3e-31
UniRef50_O96078 Cluster: EFPDE4; n=1; Ephydatia fluviatilis|Rep:... 135 1e-30
UniRef50_Q23917 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 135 2e-30
UniRef50_A7SVX8 Cluster: Predicted protein; n=1; Nematostella ve... 134 3e-30
UniRef50_UPI0000519BD4 Cluster: PREDICTED: similar to phosphodie... 130 3e-29
UniRef50_UPI0000D56A7E Cluster: PREDICTED: similar to High-affin... 130 6e-29
UniRef50_O96075 Cluster: EFPDE1; n=1; Ephydatia fluviatilis|Rep:... 127 3e-28
UniRef50_A0EBQ7 Cluster: Chromosome undetermined scaffold_88, wh... 127 3e-28
UniRef50_Q8SXR0 Cluster: RE69157p; n=9; Coelomata|Rep: RE69157p ... 127 4e-28
UniRef50_P27815 Cluster: cAMP-specific 3',5'-cyclic phosphodiest... 127 4e-28
UniRef50_UPI0000DB7125 Cluster: PREDICTED: similar to Phosphodie... 126 5e-28
UniRef50_Q23AZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 126 9e-28
UniRef50_A7SGA1 Cluster: Predicted protein; n=1; Nematostella ve... 126 9e-28
UniRef50_Q13945 Cluster: 3',5'-cyclic AMP phosphodiesterase; n=3... 126 9e-28
UniRef50_O95263 Cluster: High affinity cAMP-specific and IBMX-in... 124 3e-27
UniRef50_Q005X2 Cluster: Phosphodiesterase 1; n=1; Strongylocent... 124 4e-27
UniRef50_Q8I6Y6 Cluster: CGMP-specific phosphodiesterase; n=3; D... 123 5e-27
UniRef50_Q22000 Cluster: Probable 3',5'-cyclic phosphodiesterase... 122 9e-27
UniRef50_A2F9J4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 122 2e-26
UniRef50_Q9W4T4 Cluster: cAMP-specific 3',5'-cyclic phosphodiest... 122 2e-26
UniRef50_Q6S996 Cluster: Class I phosphodiesterase PDEB1; n=21; ... 121 2e-26
UniRef50_Q8CFW8 Cluster: Phosphodiesterase 8B; n=13; Euteleostom... 120 4e-26
UniRef50_A4RUJ3 Cluster: Predicted protein; n=1; Ostreococcus lu... 120 4e-26
UniRef50_O18696 Cluster: Probable 3',5'-cyclic phosphodiesterase... 120 4e-26
UniRef50_A0DF61 Cluster: Chromosome undetermined scaffold_49, wh... 120 5e-26
UniRef50_Q14123 Cluster: Calcium/calmodulin-dependent 3',5'-cycl... 119 8e-26
UniRef50_Q23RI8 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 118 1e-25
UniRef50_A0EGK4 Cluster: Chromosome undetermined scaffold_95, wh... 118 1e-25
UniRef50_Q388U6 Cluster: 3', 5'-cyclic nucleotide phosphodiester... 117 3e-25
UniRef50_A2DJF3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 117 3e-25
UniRef50_Q6S998 Cluster: CAMP-specific phosphodiesterase; n=3; L... 117 4e-25
UniRef50_UPI000150A113 Cluster: 3''''5''''-cyclic nucleotide pho... 116 8e-25
UniRef50_A2FBN7 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 116 1e-24
UniRef50_A4RV03 Cluster: Predicted protein; n=1; Ostreococcus lu... 115 1e-24
UniRef50_Q4D500 Cluster: Phosphodiesterase, putative; n=3; Trypa... 115 2e-24
UniRef50_A2DNV4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 115 2e-24
UniRef50_A2DF08 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 114 2e-24
UniRef50_A2ERL4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 114 3e-24
UniRef50_A2D762 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 114 3e-24
UniRef50_UPI00006CBCA5 Cluster: 3''''5''''-cyclic nucleotide pho... 113 4e-24
UniRef50_Q57V52 Cluster: 3', 5'-cyclic nucleotide phosphodiester... 113 4e-24
UniRef50_A0CB76 Cluster: Chromosome undetermined scaffold_163, w... 113 5e-24
UniRef50_A7RXZ4 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 90 6e-24
UniRef50_A7SVS5 Cluster: Predicted protein; n=1; Nematostella ve... 112 9e-24
UniRef50_Q6NNF2 Cluster: SD02170p; n=9; Diptera|Rep: SD02170p - ... 111 2e-23
UniRef50_O76083 Cluster: High affinity cGMP-specific 3',5'-cycli... 111 2e-23
UniRef50_A5K0J4 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 111 2e-23
UniRef50_UPI000065D378 Cluster: cAMP-specific 3',5'-cyclic phosp... 111 3e-23
UniRef50_Q01CI7 Cluster: Cyclic GMP phosphodiesterase; n=1; Ostr... 111 3e-23
UniRef50_A2DYU6 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 110 4e-23
UniRef50_A2DG30 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 110 4e-23
UniRef50_Q4KL87 Cluster: MGC116558 protein; n=2; Xenopus|Rep: MG... 109 7e-23
UniRef50_Q4SP32 Cluster: Chromosome 15 SCAF14542, whole genome s... 106 6e-22
UniRef50_Q4RH59 Cluster: Chromosome undetermined SCAF15069, whol... 106 8e-22
UniRef50_A3FQ29 Cluster: CGMP phosphodiesterase A4; n=2; Cryptos... 105 1e-21
UniRef50_A2ENJ2 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 105 1e-21
UniRef50_A2E8N2 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 105 2e-21
UniRef50_A2EIP4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 103 6e-21
UniRef50_UPI00015B464B Cluster: PREDICTED: similar to ENSANGP000... 102 1e-20
UniRef50_A2FQ29 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 102 1e-20
UniRef50_UPI0000D577EC Cluster: PREDICTED: similar to CG32648-PA... 101 2e-20
UniRef50_A2F408 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 101 2e-20
UniRef50_Q16VA1 Cluster: High-affinity cgmp-specific 3,5-cyclic ... 100 4e-20
UniRef50_A4HHP3 Cluster: Putative uncharacterized protein; n=3; ... 100 4e-20
UniRef50_A2FKH2 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 100 4e-20
UniRef50_Q5CXM2 Cluster: Membrane associated HD superfamily cycl... 73 5e-20
UniRef50_Q9VYJ0 Cluster: CG32648-PA; n=3; Coelomata|Rep: CG32648... 100 5e-20
UniRef50_A5JZK2 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 100 5e-20
UniRef50_UPI0000D555D7 Cluster: PREDICTED: similar to phosphodie... 99 7e-20
UniRef50_A7AS42 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 99 7e-20
UniRef50_A2DM90 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 100 9e-20
UniRef50_Q7PQX7 Cluster: ENSANGP00000010843; n=6; Coelomata|Rep:... 99 2e-19
UniRef50_A1D4A4 Cluster: High affinity cAMP phosphodiesterase, p... 98 2e-19
UniRef50_A2G2M9 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 98 3e-19
UniRef50_O00408 Cluster: cGMP-dependent 3',5'-cyclic phosphodies... 98 3e-19
UniRef50_UPI0000E48F4D Cluster: PREDICTED: similar to camp and c... 97 4e-19
UniRef50_Q4N806 Cluster: 3',5' cyclic nucleotide phosphodiestera... 97 5e-19
UniRef50_Q9HCR9 Cluster: Dual 3',5'-cyclic-AMP and -GMP phosphod... 97 5e-19
UniRef50_UPI00006CF33D Cluster: 3''''5''''-cyclic nucleotide pho... 97 7e-19
UniRef50_A7AR41 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 96 9e-19
UniRef50_A2EHB3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 96 9e-19
UniRef50_O43851 Cluster: PDE4C-delta109; n=18; Bilateria|Rep: PD... 96 9e-19
UniRef50_Q54HY3 Cluster: Putative uncharacterized protein Pde4; ... 96 1e-18
UniRef50_A2GFY4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 95 2e-18
UniRef50_O96076 Cluster: EFPDE2; n=1; Ephydatia fluviatilis|Rep:... 95 3e-18
UniRef50_Q1JT10 Cluster: Phosphodiesterase, putative; n=2; Eukar... 94 3e-18
UniRef50_O76074 Cluster: cGMP-specific 3',5'-cyclic phosphodiest... 94 5e-18
UniRef50_Q16HU8 Cluster: Camp and camp-inhibited cgmp 3,5-cyclic... 93 6e-18
UniRef50_Q9VFI9 Cluster: CG8279-PA; n=8; Endopterygota|Rep: CG82... 93 8e-18
UniRef50_O96077 Cluster: EFPDE3; n=1; Ephydatia fluviatilis|Rep:... 93 8e-18
UniRef50_Q8I0P7 Cluster: Probable 3',5'-cyclic phosphodiesterase... 93 8e-18
UniRef50_Q4SI77 Cluster: Chromosome 5 SCAF14581, whole genome sh... 93 1e-17
UniRef50_Q14432 Cluster: cGMP-inhibited 3',5'-cyclic phosphodies... 93 1e-17
UniRef50_Q4N6H0 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17
UniRef50_P91119 Cluster: Probable 3',5'-cyclic phosphodiesterase... 92 2e-17
UniRef50_Q3KVL8 Cluster: High-affinity phosphodiesterase; n=4; E... 72 2e-17
UniRef50_Q01C40 Cluster: Cyclic GMP phosphodiesterase; n=1; Ostr... 91 2e-17
UniRef50_A6S8A0 Cluster: Putative uncharacterized protein; n=2; ... 91 3e-17
UniRef50_Q3SBD3 Cluster: Sperm phosphodiesterase 5; n=1; Strongy... 91 4e-17
UniRef50_Q2V2M6 Cluster: CGMP-specific phosphodiesterase; n=3; P... 91 4e-17
UniRef50_A2EY05 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 91 4e-17
UniRef50_Q13370 Cluster: cGMP-inhibited 3',5'-cyclic phosphodies... 90 8e-17
UniRef50_Q4T098 Cluster: Chromosome undetermined SCAF11274, whol... 89 1e-16
UniRef50_Q4SVG8 Cluster: Chromosome undetermined SCAF13758, whol... 88 2e-16
UniRef50_Q4RSB8 Cluster: Chromosome 13 SCAF15000, whole genome s... 88 2e-16
UniRef50_UPI0000F1D4E2 Cluster: PREDICTED: similar to Phosphodie... 88 3e-16
UniRef50_UPI000023CCA1 Cluster: hypothetical protein FG06914.1; ... 87 7e-16
UniRef50_Q8IKD3 Cluster: Cyclic nucleotide phosphodiesterase, pu... 86 9e-16
UniRef50_A0EHP5 Cluster: Chromosome undetermined scaffold_97, wh... 86 9e-16
UniRef50_Q2H9G5 Cluster: Putative uncharacterized protein; n=1; ... 86 9e-16
UniRef50_UPI000150A9A4 Cluster: 3''''5''''-cyclic nucleotide pho... 86 1e-15
UniRef50_UPI0000588CD9 Cluster: PREDICTED: hypothetical protein;... 86 1e-15
UniRef50_A0CZ03 Cluster: Chromosome undetermined scaffold_31, wh... 86 1e-15
UniRef50_A5K353 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 85 2e-15
UniRef50_UPI00015B4531 Cluster: PREDICTED: similar to cyclic GMP... 84 4e-15
UniRef50_Q17L35 Cluster: Cgmp-dependent 3,5-cyclic phosphodieste... 84 5e-15
UniRef50_A5JZK3 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 83 7e-15
UniRef50_O94034 Cluster: Nucleotide phosphodiesterase; n=4; Sacc... 69 7e-15
UniRef50_Q7QRM3 Cluster: GLP_481_5888_1773; n=1; Giardia lamblia... 75 1e-14
UniRef50_Q0V6F8 Cluster: Putative uncharacterized protein; n=1; ... 80 6e-14
UniRef50_P30645 Cluster: Probable 3',5'-cyclic phosphodiesterase... 80 6e-14
UniRef50_UPI0000D8B81A Cluster: UPI0000D8B81A related cluster; n... 80 8e-14
UniRef50_A4RPY9 Cluster: Putative uncharacterized protein; n=1; ... 80 8e-14
UniRef50_Q7YYN8 Cluster: Phosphdiesterase, possible; n=2; Crypto... 79 1e-13
UniRef50_A3FPW6 Cluster: Phosphdiesterase, putative; n=1; Crypto... 79 1e-13
UniRef50_A2E0V4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 79 1e-13
UniRef50_A6R1R4 Cluster: Predicted protein; n=1; Ajellomyces cap... 79 1e-13
UniRef50_Q6CHK1 Cluster: Similar to tr|Q8NJP9 Candida albicans H... 79 2e-13
UniRef50_UPI0000E46CDB Cluster: PREDICTED: similar to phosphodie... 78 3e-13
UniRef50_Q3UEI1-2 Cluster: Isoform 2 of Q3UEI1 ; n=1; Mus muscul... 78 3e-13
UniRef50_Q7Q8G2 Cluster: ENSANGP00000013023; n=2; Diptera|Rep: E... 77 4e-13
UniRef50_Q53I59 Cluster: Cyclic nucleotide specific phosphodiest... 77 4e-13
UniRef50_A2FQB0 Cluster: GAF domain containing protein; n=1; Tri... 77 4e-13
UniRef50_Q1DXU2 Cluster: Putative uncharacterized protein; n=1; ... 76 1e-12
UniRef50_P06776 Cluster: 3',5'-cyclic-nucleotide phosphodiestera... 75 2e-12
UniRef50_A0D3N1 Cluster: Chromosome undetermined scaffold_36, wh... 75 3e-12
UniRef50_P16499 Cluster: Rod cGMP-specific 3',5'-cyclic phosphod... 74 4e-12
UniRef50_UPI0001554EBF Cluster: PREDICTED: similar to cyclic nuc... 74 5e-12
UniRef50_A0E2C5 Cluster: Chromosome undetermined scaffold_74, wh... 74 5e-12
UniRef50_Q9VJ79 Cluster: Dual 3',5'-cyclic-AMP and -GMP phosphod... 74 5e-12
UniRef50_Q4FXD4 Cluster: Putative uncharacterized protein; n=3; ... 73 9e-12
UniRef50_Q7RXW7 Cluster: Putative uncharacterized protein NCU004... 73 9e-12
UniRef50_Q4SPD6 Cluster: Chromosome 16 SCAF14537, whole genome s... 73 1e-11
UniRef50_Q6FM93 Cluster: Similar to sp|P06776 Saccharomyces cere... 72 2e-11
UniRef50_Q9Y233 Cluster: cAMP and cAMP-inhibited cGMP 3',5'-cycl... 71 3e-11
UniRef50_A5DVX9 Cluster: Putative uncharacterized protein; n=1; ... 71 4e-11
UniRef50_UPI0000660DD6 Cluster: Homolog of Homo sapiens "Phospho... 70 6e-11
UniRef50_Q758Y3 Cluster: ADR395Cp; n=1; Eremothecium gossypii|Re... 70 9e-11
UniRef50_Q6BSL2 Cluster: Similar to tr|O94034 Candida albicans N... 69 1e-10
UniRef50_UPI0001555C30 Cluster: PREDICTED: hypothetical protein,... 69 2e-10
UniRef50_A7SW30 Cluster: Predicted protein; n=2; Nematostella ve... 69 2e-10
UniRef50_Q4RG61 Cluster: Chromosome 2 SCAF15106, whole genome sh... 68 3e-10
UniRef50_A2E4B2 Cluster: Response regulator receiver domain cont... 68 3e-10
UniRef50_Q57ZK5 Cluster: 3', 5'-cyclic nucleotide phosphodiester... 68 3e-10
UniRef50_A7TPP3 Cluster: Putative uncharacterized protein; n=1; ... 68 3e-10
UniRef50_A4VDP2 Cluster: Cyclic nucleotide phosphodiesterase; n=... 67 5e-10
UniRef50_A0BZW8 Cluster: Chromosome undetermined scaffold_14, wh... 67 5e-10
UniRef50_Q29FT2 Cluster: GA17041-PA; n=1; Drosophila pseudoobscu... 67 6e-10
UniRef50_A2E5S0 Cluster: GAF domain containing protein; n=1; Tri... 66 8e-10
UniRef50_Q6CY30 Cluster: Similar to sp|P06776 Saccharomyces cere... 66 1e-09
UniRef50_A2DM77 Cluster: GAF domain containing protein; n=1; Tri... 66 1e-09
UniRef50_A0DIM1 Cluster: Chromosome undetermined scaffold_52, wh... 66 1e-09
UniRef50_Q22CV4 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 65 2e-09
UniRef50_A0E1V7 Cluster: Chromosome undetermined scaffold_74, wh... 64 4e-09
UniRef50_A0CU34 Cluster: Chromosome undetermined scaffold_28, wh... 62 1e-08
UniRef50_A0CZB5 Cluster: Chromosome undetermined scaffold_32, wh... 62 2e-08
UniRef50_UPI00006CB6E9 Cluster: 3''''5''''-cyclic nucleotide pho... 61 4e-08
UniRef50_A0D565 Cluster: Chromosome undetermined scaffold_38, wh... 61 4e-08
UniRef50_A2DBZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 60 7e-08
UniRef50_A2FK96 Cluster: GAF domain containing protein; n=3; Tri... 60 9e-08
UniRef50_A2DCH1 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 59 1e-07
UniRef50_A0EF18 Cluster: Chromosome undetermined scaffold_92, wh... 58 3e-07
UniRef50_Q5C1P7 Cluster: SJCHGC07646 protein; n=1; Schistosoma j... 57 6e-07
UniRef50_Q5BYM4 Cluster: SJCHGC06481 protein; n=1; Schistosoma j... 56 9e-07
UniRef50_A2F4K8 Cluster: GAF domain containing protein; n=1; Tri... 55 2e-06
UniRef50_Q4RHZ1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 54 3e-06
UniRef50_Q95Z92 Cluster: Possible phosphodiesterase; n=2; Leishm... 54 3e-06
UniRef50_A0BZK9 Cluster: Chromosome undetermined scaffold_139, w... 52 2e-05
UniRef50_Q4SV96 Cluster: Chromosome 10 SCAF13771, whole genome s... 51 3e-05
UniRef50_A2FET3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 51 3e-05
UniRef50_A2FCG2 Cluster: GAF domain containing protein; n=1; Tri... 51 3e-05
UniRef50_UPI000065CC62 Cluster: cGMP-inhibited 3',5'-cyclic phos... 50 7e-05
UniRef50_UPI000065E700 Cluster: Cone cGMP-specific 3',5'-cyclic ... 49 2e-04
UniRef50_Q4DUD4 Cluster: CAMP-specific phosphodiesterase, putati... 47 5e-04
UniRef50_UPI00006A17C5 Cluster: cGMP-inhibited 3',5'-cyclic phos... 47 7e-04
UniRef50_Q4SVG0 Cluster: Chromosome 1 SCAF13759, whole genome sh... 46 0.001
UniRef50_Q4QE95 Cluster: Putative uncharacterized protein; n=3; ... 46 0.001
UniRef50_A0CG66 Cluster: Chromosome undetermined scaffold_179, w... 46 0.001
UniRef50_A2EA57 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 45 0.002
UniRef50_Q4DJ46 Cluster: Putative uncharacterized protein; n=2; ... 44 0.004
UniRef50_UPI00006CD10E Cluster: 3''''5''''-cyclic nucleotide pho... 43 0.009
UniRef50_Q4RNP2 Cluster: Chromosome 2 SCAF15010, whole genome sh... 43 0.009
UniRef50_Q22VA7 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 42 0.020
UniRef50_A2FSQ8 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 42 0.026
UniRef50_Q6MQQ9 Cluster: Putative uncharacterized protein precur... 35 2.3
UniRef50_Q8STT1 Cluster: Putative uncharacterized protein ECU09_... 35 2.3
UniRef50_Q6UWE0 Cluster: E3 ubiquitin-protein ligase LRSAM1; n=3... 35 2.3
UniRef50_Q53S13 Cluster: Putative uncharacterized protein PDE11A... 35 3.0
UniRef50_Q0S6Y0 Cluster: Probable CoA-transferase; n=3; Actinomy... 34 4.0
UniRef50_A0YBF8 Cluster: Putative uncharacterized protein; n=1; ... 34 4.0
UniRef50_UPI00015B5A6A Cluster: PREDICTED: similar to conserved ... 33 6.9
UniRef50_A2G4P7 Cluster: GAF domain containing protein; n=1; Tri... 33 9.1
>UniRef50_Q16J23 Cluster: Camp-specific 3,5-cyclic
phosphodiesterase; n=2; Culicidae|Rep: Camp-specific
3,5-cyclic phosphodiesterase - Aedes aegypti
(Yellowfever mosquito)
Length = 872
Score = 338 bits (832), Expect = 7e-92
Identities = 156/264 (59%), Positives = 197/264 (74%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
KLF+L E GYHSTNPYHNSIHATDVTQAMHCFL + I + P+EI+A L+ A+ HD+
Sbjct: 152 KLFSLIEEGYHSTNPYHNSIHATDVTQAMHCFLQEKRILENLSPLEIMASLIGAVTHDLD 211
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE 380
HPGVNQ FLIAT NHLA LY EN SVLE+HHWR+A+ C++ESG+ E+ ++ E
Sbjct: 212 HPGVNQPFLIATSNHLAALY-------ENTSVLENHHWRSAVGCLLESGVAEQIQGIRPE 264
Query: 381 LKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRP 560
L+K + LI+ATDITRQ +++S+F+ L +TLDMR +EHR +LQIALKCADISNPCRP
Sbjct: 265 LEKQISSLILATDITRQQEFISQFRDYLSHDTLDMRNKEHRHFILQIALKCADISNPCRP 324
Query: 561 WSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITEW 740
W +S+KWS+KVCEEFFRQGDYE+ L+LPVT LCDR STS+P + P + EW
Sbjct: 325 WDISKKWSLKVCEEFFRQGDYERQLNLPVTSLCDRHSTSVPKIQTGFF-KFVVTPLMDEW 383
Query: 741 NRFLDSKLSXEMXANXXYNEVQWE 812
+RFL + LS M + YN++QWE
Sbjct: 384 HRFLKTDLSYNMMHHLKYNQIQWE 407
>UniRef50_UPI00015B4893 Cluster: PREDICTED: similar to camp-specific
3,5-cyclic phosphodiesterase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to camp-specific
3,5-cyclic phosphodiesterase - Nasonia vitripennis
Length = 1229
Score = 336 bits (825), Expect = 5e-91
Identities = 157/268 (58%), Positives = 196/268 (73%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
KLFTL E GYHSTNPYHNSIHA DVTQAMHCFL + IR + +EI+A L++A+ HD+
Sbjct: 276 KLFTLIEEGYHSTNPYHNSIHAADVTQAMHCFLQEEQIRRHLSYLEIMASLIAAVTHDLD 335
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPD-LQE 377
HPGVNQ FL+AT NHLA LY EN SVLE+HHWR+A+ C++ESG+ E+ PD ++
Sbjct: 336 HPGVNQPFLVATSNHLAALY-------ENTSVLENHHWRSAVGCLLESGVSEQLPDRVKP 388
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
EL++H+ LI+ATDITRQ ++L+RFK+ LD LDM EHR +LQIALKCADISNPCR
Sbjct: 389 ELQRHISSLILATDITRQQEFLTRFKRYLDERELDMEQPEHRHFILQIALKCADISNPCR 448
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
PW +S+KWS KVCEEFFRQGDYE+ L+LPVT LCDR +TSIP + LP E
Sbjct: 449 PWDISRKWSYKVCEEFFRQGDYERQLNLPVTALCDRHTTSIPKIQAGFF-KFVVLPLYEE 507
Query: 738 WNRFLDSKLSXEMXANXXYNEVQWELLM 821
W+RFLD S + + N+ WEL++
Sbjct: 508 WHRFLDDDFSRSLMRHLRANQQHWELMI 535
>UniRef50_UPI0000DB6B8B Cluster: PREDICTED: similar to
phosphodiesterase 7A isoform a; n=1; Apis mellifera|Rep:
PREDICTED: similar to phosphodiesterase 7A isoform a -
Apis mellifera
Length = 1148
Score = 320 bits (787), Expect = 2e-86
Identities = 151/268 (56%), Positives = 192/268 (71%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
KLF E GYHSTNPYHNSIHATDVTQAMHCFL + IR + +EI+A L++A+ HD+
Sbjct: 81 KLFAFIEEGYHSTNPYHNSIHATDVTQAMHCFLQEEKIRTHLTNLEIMASLIAAVTHDLD 140
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FL+AT NHLA LY +N SVLE+HHWR+A+ C++ESG+ ++ P ++
Sbjct: 141 HPGVNQPFLVATSNHLAALY-------QNTSVLENHHWRSAIGCLLESGVSDQLPAHVRP 193
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
EL++H+ LI+ATDITRQ ++L RFK LD N L+M+ + R +LQIALKCADISNPCR
Sbjct: 194 ELQRHISSLILATDITRQQEFLIRFKHYLDENLLEMKRADDRHFILQIALKCADISNPCR 253
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
PW +SQKWS KVCEEFFRQGDYE+ L+LPVT LCDR +TSIP + P E
Sbjct: 254 PWDISQKWSHKVCEEFFRQGDYERRLNLPVTPLCDRHTTSIPKIQAGFF-KFVVTPLYEE 312
Query: 738 WNRFLDSKLSXEMXANXXYNEVQWELLM 821
W+RFL LS + + N+ +WE L+
Sbjct: 313 WHRFLGDGLSVSLMEHLRANQKKWEALI 340
>UniRef50_Q13946 Cluster: High affinity cAMP-specific 3',5'-cyclic
phosphodiesterase 7A; n=73; Euteleostomi|Rep: High
affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
- Homo sapiens (Human)
Length = 482
Score = 249 bits (610), Expect = 6e-65
Identities = 122/265 (46%), Positives = 168/265 (63%), Gaps = 1/265 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + + P +I+ L++A HD+
Sbjct: 196 RFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLD 255
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T ++LA LY+ N SVLE+HHWR+A+ + ESGL P + ++
Sbjct: 256 HPGVNQPFLIKTNHYLATLYK-------NTSVLENHHWRSAVGLLRESGLFSHLPLESRQ 308
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
+++ + LI+ATDI+RQ++YLS F+ LD L + HR LVLQ+ALKCADI NPCR
Sbjct: 309 QMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLEDTRHRHLVLQMALKCADICNPCR 368
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS KV EEFF QGD EK L V+ LCDR + SI N Y P TE
Sbjct: 369 TWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESI-ANIQIGFMTYLVEPLFTE 427
Query: 738 WNRFLDSKLSXEMXANXXYNEVQWE 812
W RF +++LS M + N+ W+
Sbjct: 428 WARFSNTRLSQTMLGHVGLNKASWK 452
>UniRef50_Q4RR95 Cluster: Chromosome 14 SCAF15003, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 14 SCAF15003, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 456
Score = 239 bits (586), Expect = 5e-62
Identities = 120/281 (42%), Positives = 174/281 (61%), Gaps = 19/281 (6%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ + YHS NPYHN++HA DVTQAM+C+L + + + P+++ L++A AHD+ HPGV
Sbjct: 178 MVQEDYHSQNPYHNAVHAADVTQAMYCYLKEPKLAEQLSPLDVFLGLMAAAAHDVDHPGV 237
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQEELKK 389
NQ FLI T +HLA LY++ + +N SVLESHHWR+ + + ESGLL P D+ +++++
Sbjct: 238 NQPFLIKTRHHLASLYQVHQSV-QNTSVLESHHWRSTVGMLRESGLLSHLPADMSQDIEQ 296
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVL-----------------Q 518
L LI+ATDI+RQ+++L F + LD LD+++ HR +L Q
Sbjct: 297 QLGSLILATDISRQNEFLLTFGEHLDHQDLDLQLPSHRHFILQHAFRRSVPAVTACVCQQ 356
Query: 519 IALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNX 698
IALKCAD+ NPCR W++S++WS +VCEEFFRQGD E+ DL ++ LCD T
Sbjct: 357 IALKCADVCNPCRVWALSRQWSERVCEEFFRQGDLERKFDLEISPLCDSRRLRPAIQTGF 416
Query: 699 LL*IYXSLPXITEWNRFLD-SKLSXEMXANXXYNEVQWELL 818
+ Y P EW+RF + S LS M + N+ +W L
Sbjct: 417 I--SYIVEPLFDEWHRFTEPSPLSRTMMGHLHQNKARWSRL 455
>UniRef50_UPI0000E7FF0E Cluster: PREDICTED: similar to cAMP
phosphodiesterase PDE7, partial; n=1; Gallus gallus|Rep:
PREDICTED: similar to cAMP phosphodiesterase PDE7,
partial - Gallus gallus
Length = 482
Score = 217 bits (531), Expect = 2e-55
Identities = 103/217 (47%), Positives = 145/217 (66%), Gaps = 1/217 (0%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ + YHS NPYHN++HA DVTQAMHC+L + + + P +++ L++A HD+ HPGV
Sbjct: 1 MVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLSESLTPWDVLLSLIAAATHDLDHPGV 60
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQEELKK 389
NQ FLI T ++LA LY+ N SVLE+HHWR+A+ + ESGL + ++ ++
Sbjct: 61 NQPFLIKTNHYLATLYK-------NTSVLENHHWRSAVGLLRESGLFAHMSLENRQLMES 113
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
+ LI+ATDI++Q++YLS F+ LD L + HR +LQ+ALKCADI NPCR W +
Sbjct: 114 QIGDLILATDISQQNEYLSMFRSHLDRGDLCLEDANHRHFILQMALKCADICNPCRTWEL 173
Query: 570 SQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
S++WS KV EEFF QGD EK L V+ LCDR + +I
Sbjct: 174 SKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTETI 210
Score = 187 bits (456), Expect = 3e-46
Identities = 96/224 (42%), Positives = 137/224 (61%), Gaps = 1/224 (0%)
Frame = +3
Query: 144 IRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAA 323
+ P +++ L++A HD+ HPGVNQ FLI T ++LA LY+ N SVLE+HHWR+A
Sbjct: 235 LTPWDVLLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYK-------NTSVLENHHWRSA 287
Query: 324 LSCIIESGLLEERP-DLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEH 500
+ + ESGL + ++ ++ + LI+ATDI++Q++YLS F+ LD L + H
Sbjct: 288 VGLLRESGLFAHMSLENRQLMESQIGDLILATDISQQNEYLSMFRSHLDRGDLCLEDANH 347
Query: 501 RILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
R +LQ+ALKCADI NPCR W +S++WS KV EEFF QGD EK L V+ LCDR + +I
Sbjct: 348 RHFILQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTETI 407
Query: 681 PXNTNXLL*IYXSLPXITEWNRFLDSKLSXEMXANXXYNEVQWE 812
N Y P EW RF +++LS M + N+ W+
Sbjct: 408 -ANIQIGFMTYLVEPLFAEWARFSNTRLSQTMLGHLGLNKASWK 450
>UniRef50_UPI00015B5210 Cluster: PREDICTED: similar to
ENSANGP00000018818; n=2; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000018818 - Nasonia
vitripennis
Length = 849
Score = 145 bits (351), Expect = 1e-33
Identities = 91/268 (33%), Positives = 145/268 (54%), Gaps = 5/268 (1%)
Frame = +3
Query: 30 TLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPG 209
T+ E+ Y+S YHNS HATDV QA F+ I+ + P++ +A LL+A AHDI HPG
Sbjct: 566 TIIEANYNSHVSYHNSTHATDVLQACARFMRSDRIQQILDPLDEVAALLAAAAHDIGHPG 625
Query: 210 VNQGFLIATCNHLADLYRILEGTSENFSVLESHH----WRAALSCIIESGLLEERPDLQE 377
+ FL T N LA LY + +VLESHH ++ LS + D+ +
Sbjct: 626 KSSQFLCNTSNKLAILY-------NDLTVLESHHSALTFKVTLSDDNVNIFKNLHADVYK 678
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
+++++ +I+AT++T+ ++L+RF L DT+ + E+ L ++ +KCAD+SNP R
Sbjct: 679 SMRQNIIDMILATEMTKHFEHLARFVNLFDTSA--FLLPENVTLTKRMMIKCADVSNPTR 736
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIPXNTNXLL*IYXSLPXIT 734
P+ + +W+ ++ EE+F Q D EK LPV + DR IP + + Y +
Sbjct: 737 PFRLYVEWTRRIAEEYFDQTDEEKKKKLPVVMPMFDRACCCIPKSQIGFV-EYIINDMME 795
Query: 735 EWNRFLDSKLSXEMXANXXYNEVQWELL 818
W+ F+D EM N ++W+ L
Sbjct: 796 AWDAFID---MPEMVGYMSENYMKWKEL 820
>UniRef50_Q9N2V9 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-6; n=3; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-6 - Caenorhabditis elegans
Length = 760
Score = 137 bits (332), Expect = 3e-31
Identities = 77/221 (34%), Positives = 125/221 (56%), Gaps = 6/221 (2%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E+ YH+ N YHN+ HA DV QA FL S+ + +A LL+A HD+ HPG
Sbjct: 492 EAHYHAGNTYHNATHAADVLQATSFFLDSPSVAVHVNESHAVAALLAAAVHDLDHPGRGN 551
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL---LEERPDLQEELK- 386
+LI T LA LY ++N S+LE+HH A ++ + +E ++
Sbjct: 552 AYLINTRQSLAILY------NDN-SILENHHIALAFQLTLQHNANVNIFSSLSREEFIQM 604
Query: 387 KHLKV-LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
+H V +++ATDI+R +YL++F K+ T+ + + + + + + +KCADISNP R W
Sbjct: 605 RHAMVEMVLATDISRHFEYLAKFNKMHVTDVPEEQRDTNSLTICDMLVKCADISNPAREW 664
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVT-QLCDRDSTSIP 683
+ Q+W+ ++ EE+F Q EK LPVT ++ DR++ ++P
Sbjct: 665 GLCQRWAHRIVEEYFEQTREEKEKGLPVTMEVFDRNTCNVP 705
>UniRef50_O96078 Cluster: EFPDE4; n=1; Ephydatia fluviatilis|Rep:
EFPDE4 - Ephydatia fluviatilis
Length = 698
Score = 135 bits (327), Expect = 1e-30
Identities = 84/223 (37%), Positives = 126/223 (56%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
ES YHS NPYHN++HA DV A + L ++ +E+ A L++AI HD+ HPG N
Sbjct: 406 ESKYHS-NPYHNALHAADVLLATNHLLKAKALEPIFTQLEVFAALVAAIIHDVDHPGRNN 464
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIE--SGLLEERPDLQEELKKH 392
FL++T + LA LY + SVLE+HH A + + LE Q++ +
Sbjct: 465 QFLVSTEDPLAILY-------NDESVLENHHLALAFELMKDPTCNFLESTCKSQKQAFRK 517
Query: 393 LKV-LIMATDITRQHDYLSRFKKLLDTN------TLDMRIQEHRILVLQIALKCADISNP 551
L + +++ATD++R YL + K LL++N L + R+ VLQ L CAD+SN
Sbjct: 518 LIIDMVLATDMSRHFKYLGQLKTLLESNKVANNGLLQLDKYHDRVEVLQGLLHCADLSNQ 577
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++ +WS ++ EE +RQGD E+ L +PV L DR S SI
Sbjct: 578 TKSFHIASQWSQRIMEESYRQGDEERKLGIPVNPLGDR-SVSI 619
>UniRef50_Q23917 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase
regA; n=2; Dictyostelium discoideum|Rep:
3',5'-cyclic-nucleotide phosphodiesterase regA -
Dictyostelium discoideum (Slime mold)
Length = 793
Score = 135 bits (326), Expect = 2e-30
Identities = 72/213 (33%), Positives = 114/213 (53%), Gaps = 3/213 (1%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
Y N YHN HA DVTQ ++ FL + ++ ++I A L+S + HD+ HPG N F
Sbjct: 480 YRKNNRYHNFTHAFDVTQTVYTFLTSFNAAQYLTHLDIFALLISCMCHDLNHPGFNNTFQ 539
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCI--IESGLLEE-RPDLQEELKKHLK 398
+ L+ Y + SVLE+HH + E +LE D +EL++ +
Sbjct: 540 VNAQTELSLEYN-------DISVLENHHAMLTFKILRNSECNILEGLNEDQYKELRRSVV 592
Query: 399 VLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
LI+ATD+ ++ ++F+ L+ D +E R ++L +KC DISN RPW ++ +
Sbjct: 593 QLILATDMQNHFEHTNKFQHHLNNLPFDRNKKEDRQMILNFLIKCGDISNIARPWHLNFE 652
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
WS++V +EFF+Q YE + PVT D+ T+
Sbjct: 653 WSLRVSDEFFQQSHYETICGYPVTPFMDKTKTT 685
>UniRef50_A7SVX8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 844
Score = 134 bits (324), Expect = 3e-30
Identities = 80/234 (34%), Positives = 130/234 (55%), Gaps = 17/234 (7%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
L E+ YH N YHNS HA DV A FL + ++A + P++ +A L++AI HD+ HPG
Sbjct: 569 LIEANYHRKNAYHNSTHAADVLHATAVFLAKERVKAVLEPLDEVASLIAAIVHDVDHPGY 628
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAA--LSCIIESGLLEERPDLQE--E 380
FL + LA LY + +VLESHH A L+ + + D++E
Sbjct: 629 TNSFLCNAGSELAILY-------NDIAVLESHHAALAFKLTARDDKSNIFSNLDVEEFRT 681
Query: 381 LKKHLKVLIMATDITRQHDYLSRFKKLL---------DTNT---LDMRIQEHRILVLQIA 524
+++ + ++MAT++TR ++LS+F + D+NT + E+R L+ ++
Sbjct: 682 VRQAIIDMVMATEMTRHFEHLSKFVNSINKRRSSSTPDSNTSTSTALNTPENRTLIKRML 741
Query: 525 LKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
+KCADI+NP RP + ++W+ ++ EE+F Q D EK LPV + DR + ++P
Sbjct: 742 IKCADIANPARPRYLCKEWAYRIAEEYFSQTDEEKRRGLPVVMPVFDRATCNVP 795
>UniRef50_UPI0000519BD4 Cluster: PREDICTED: similar to
phosphodiesterase 8A; n=1; Apis mellifera|Rep: PREDICTED:
similar to phosphodiesterase 8A - Apis mellifera
Length = 820
Score = 130 bits (315), Expect = 3e-29
Identities = 80/235 (34%), Positives = 125/235 (53%), Gaps = 18/235 (7%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ Y TN YHNS HA DV QA F+ ++ + P++ +A L++A AHDI HPG
Sbjct: 524 VIEANYDITNRYHNSTHAADVLQAAAMFMQTERLKQVLEPLDEVATLIAAAAHDIDHPGR 583
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKH 392
+ FL + N LA LY + +VLESHH + + +L+ + K
Sbjct: 584 SSQFLCNSDNKLAILY-------NDLTVLESHHAALTFKLTLSDDNVNIFKNLERDTYKQ 636
Query: 393 LKV----LIMATDITRQHDYLSRFKKLLDTNTLDMRIQ-------------EHRILVLQI 521
++ +I+AT++T+ ++L++F T +M I+ E+ ILV ++
Sbjct: 637 VRQSVIDMILATEMTKHFEHLAKFMNAFSTRIPEMYIEGSQDLDLSAAILPENVILVKRM 696
Query: 522 ALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
+KCAD+SNP RP +W+ ++ EE+F Q D EK L LPV + DR + SIP
Sbjct: 697 IIKCADVSNPTRPLKYCVEWARRIAEEYFSQTDEEKQLHLPVMMPMFDRITCSIP 751
>UniRef50_UPI0000D56A7E Cluster: PREDICTED: similar to High-affinity
cAMP-specific and IBMX-insensitive 3,5-cyclic
phosphodiesterase 8A; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to High-affinity cAMP-specific and
IBMX-insensitive 3,5-cyclic phosphodiesterase 8A -
Tribolium castaneum
Length = 862
Score = 130 bits (313), Expect = 6e-29
Identities = 82/277 (29%), Positives = 143/277 (51%), Gaps = 17/277 (6%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YH+ N YHNS HA DV QA FL + +++ + P++ L++A AHD+ HPG
Sbjct: 567 IIEANYHTDNTYHNSTHAADVMQATAGFLEREKLKSIMDPLDEATSLIAAAAHDVDHPGK 626
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE---L 383
+ FL + N LA LY + ++LESHH + + +L E +
Sbjct: 627 SNAFLSNSDNPLAILY-------NDITILESHHAALMFKLTLGDERVNVFKNLDRETYKI 679
Query: 384 KKHLKV-LIMATDITRQHDYLSRFKKLLDTNTLDMRIQ------------EHRILVLQIA 524
+H + +I+AT++T+ ++L++F + T T + I+ E+ L+ ++
Sbjct: 680 ARHNVIDMILATEMTKHFEHLAKFVNVFCTKTSNSDIELGDQDFPLLTQPENITLIKRMM 739
Query: 525 LKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIPXNTNXL 701
+KC+D+SNP RP + +W+ ++ EE+F+Q D EK LPV + DR++ SIP +
Sbjct: 740 IKCSDVSNPTRPLRLCVEWARRIAEEYFQQTDEEKERGLPVVMPMFDRNTCSIPKSQIGF 799
Query: 702 L*IYXSLPXITEWNRFLDSKLSXEMXANXXYNEVQWE 812
+ Y WN F+D ++ N ++W+
Sbjct: 800 V-DYIINDMFEAWNAFID---MPDLITYMRQNYIRWK 832
>UniRef50_O96075 Cluster: EFPDE1; n=1; Ephydatia fluviatilis|Rep:
EFPDE1 - Ephydatia fluviatilis
Length = 628
Score = 127 bits (307), Expect = 3e-28
Identities = 76/219 (34%), Positives = 123/219 (56%), Gaps = 4/219 (1%)
Frame = +3
Query: 39 ESGYH-STNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E+GY NPYHNS HA DV Q +H + + +I +E++A LL+A HD+ H G
Sbjct: 268 EAGYQLHGNPYHNSTHAADVLQTVHYLISSTGLEHWISSLEVLAILLAATVHDLEHTGTT 327
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL-LEERPDLQE-ELKK 389
F I + A LY + +VLE+ H A + + E L + + L++ L +
Sbjct: 328 NTFHIQSYTDYALLYN-------DRAVLENFHLNRAFTLLKEDELNILKNLKLEDFRLVR 380
Query: 390 HLKV-LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
L V +++ATD++ D L ++L+ + + ++I++ R VL + L ADIS+P + W
Sbjct: 381 SLVVEMVLATDMSSHSDQLKHMRQLISSPDVIVQIEKGRSKVLCLLLHMADISHPGKEWE 440
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
Q++S ++ EEFFRQGD E L + LC+R++TS+P
Sbjct: 441 THQEFSSRLVEEFFRQGDQEMQLGRTCSPLCNRNTTSVP 479
>UniRef50_A0EBQ7 Cluster: Chromosome undetermined scaffold_88, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_88, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 744
Score = 127 bits (307), Expect = 3e-28
Identities = 70/212 (33%), Positives = 119/212 (56%), Gaps = 3/212 (1%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
++ NPYHNSIHA DV + FL G + P E ++SA++HD+ HPG+N GFL
Sbjct: 459 FYMQNPYHNSIHAMDVANSASFFLENG---LEVTPFEQCCLIISALSHDVGHPGLNNGFL 515
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIE--SGLLEERPDLQEE-LKKHLK 398
+A+ + A +Y + SVLES+H + + + +L+ D+ + +K+
Sbjct: 516 VASQSKQALIYN-------DQSVLESYHASLMFHVLKDEKANILKNINDVDYKGFRKYCL 568
Query: 399 VLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
LI+ TD+ + L++FK L + ++ ++L+L IA+KCAD+ + + ++ +
Sbjct: 569 NLILDTDLQKHFPLLNKFKNFLALGSDSQSDEQTKLLILSIAIKCADVGHGAKQLNLHKI 628
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQLCDRDST 674
WS ++ EEFF QGD E + + VT +CDR +
Sbjct: 629 WSRRIIEEFFLQGDLEAQVGIQVTPMCDRSQS 660
>UniRef50_Q8SXR0 Cluster: RE69157p; n=9; Coelomata|Rep: RE69157p -
Drosophila melanogaster (Fruit fly)
Length = 834
Score = 127 bits (306), Expect = 4e-28
Identities = 74/218 (33%), Positives = 115/218 (52%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGY-HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN++HA DV Q +H L + ++ +EI A LL+A+ HD H G
Sbjct: 458 EEGYCRYRNPYHNNLHAVDVMQTIHYCLCNTGLMNWLTDLEIFASLLAALLHDYEHTGTT 517
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQ-EELK 386
F + + + A LY + +VLE+HH A+ + E +L + EL+
Sbjct: 518 NNFHVMSGSETALLYN-------DRAVLENHHASASFRLLREDEYNILSHLSREEFRELR 570
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ +++ TD+T + ++LL + Q+ VL + L C DIS+P + W
Sbjct: 571 GLVIEMVLGTDMTNHFQQMKAMRQLLTLQEATIDKQK----VLSLVLHCCDISHPAKQWG 626
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
V +W++ + EEFFRQGD EK L LP + LCDR++T +
Sbjct: 627 VHHRWTMLLLEEFFRQGDLEKELGLPFSPLCDRNNTLV 664
>UniRef50_P27815 Cluster: cAMP-specific 3',5'-cyclic phosphodiesterase
4A; n=160; Eumetazoa|Rep: cAMP-specific 3',5'-cyclic
phosphodiesterase 4A - Homo sapiens (Human)
Length = 886
Score = 127 bits (306), Expect = 4e-28
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 423 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 482
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 483 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 535
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 536 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 595
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 596 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 638
>UniRef50_UPI0000DB7125 Cluster: PREDICTED: similar to
Phosphodiesterase 1c CG14940-PA; n=1; Apis mellifera|Rep:
PREDICTED: similar to Phosphodiesterase 1c CG14940-PA -
Apis mellifera
Length = 731
Score = 126 bits (305), Expect = 5e-28
Identities = 73/218 (33%), Positives = 118/218 (54%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGY-HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN++HA DV Q MH L Q + ++ +EI A L++AI HD H G
Sbjct: 430 EEGYCRHRNPYHNNLHAADVAQTMHYILCQTGLMNWLTDLEIFATLVAAIIHDYEHTGTT 489
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHL 395
F + + + A LY + +VLE+HH A+ + E + +EE ++
Sbjct: 490 NNFHVMSGSDTALLYN-------DRAVLENHHISASFRIMREDECNILQNLSREEFREFR 542
Query: 396 KVLI---MATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
++I +ATD++ L K +L + + + + + + + L C DIS+P + W
Sbjct: 543 SLVIDMVLATDMSFHFQQLKNMKNIL--SLAEPSVDKSK--AVSLVLHCCDISHPAKRWD 598
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++++ EEFFRQGD EK L LP + LCDR++T +
Sbjct: 599 LHHRWTMQLLEEFFRQGDKEKALGLPFSPLCDRNNTLV 636
>UniRef50_Q23AZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Tetrahymena thermophila SB210
Length = 577
Score = 126 bits (303), Expect = 9e-28
Identities = 84/269 (31%), Positives = 134/269 (49%), Gaps = 6/269 (2%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIR--AFIRPVEIIACLLSAIAHDIFHPGV 212
++GY NPYH+ +H+ DVTQ +H F+ + A ++ +E A SA HD HPG
Sbjct: 302 QNGYRD-NPYHDRLHSFDVTQTIHFFISRCKFGELAKLKSMERAAMYFSAAIHDFDHPGY 360
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKH 392
N FLI T N LA + + SVLE+HH + I+++ L + + K
Sbjct: 361 NNVFLINTQNILALKFN-------DQSVLENHHVSSVYEMILKNHNLNIFSNFSNDEYKQ 413
Query: 393 LKVLI----MATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRP 560
+ ++ +ATD+T+ +S+ K + ++ ++ + V++ L +DISNP RP
Sbjct: 414 FREMVVNMVLATDMTKHFADISKLKSRIAATDFEIDGKDKKT-VMESLLHASDISNPARP 472
Query: 561 WSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITEW 740
W + +W+ KV EF+ QGD EK L LPVT LCDR T+ + + + P
Sbjct: 473 WEICYQWTNKVMTEFWAQGDEEKRLGLPVTYLCDRVETNTSKSQQGFI-DFVVKPLFEII 531
Query: 741 NRFLDSKLSXEMXANXXYNEVQWELLMTK 827
+ FL + N N+ +W L+ K
Sbjct: 532 SNFLPE--LQQFMINFEQNKEKWAELLPK 558
>UniRef50_A7SGA1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 358
Score = 126 bits (303), Expect = 9e-28
Identities = 83/223 (37%), Positives = 119/223 (53%), Gaps = 8/223 (3%)
Frame = +3
Query: 39 ESGY-HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E+GY +NPYHN HA DVT +H FL + ++ +E+ LLSAI HD+ H G
Sbjct: 129 ETGYKRHSNPYHNDCHAADVTHTVHYFLECMGVSKYLSDLEVFGLLLSAIIHDLEHTGTT 188
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI------IESGL-LEERPDLQ 374
F I + + LA LY + SVLE+HH A + I SGL LE+ D++
Sbjct: 189 NAFHINSRSDLALLYN-------DRSVLENHHVSCAFRILQDDEKNILSGLNLEQYADVR 241
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPC 554
+ ++ATD++ + L K L + I+ V+Q+ L ADISNP
Sbjct: 242 SLMID----TVLATDMSSHFEQLRLMKVALVAGS---PIENRE--VVQLLLHVADISNPT 292
Query: 555 RPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+ W++ ++W+ K+ EEFF QGD E L L V+ LCDR +T IP
Sbjct: 293 KDWTIHRQWTTKIMEEFFTQGDMEIELGLDVSPLCDRSTTLIP 335
>UniRef50_Q13945 Cluster: 3',5'-cyclic AMP phosphodiesterase; n=37;
Coelomata|Rep: 3',5'-cyclic AMP phosphodiesterase - Homo
sapiens (Human)
Length = 606
Score = 126 bits (303), Expect = 9e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 266 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 325
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 326 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 378
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 379 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 438
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 439 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 481
>UniRef50_O95263 Cluster: High affinity cAMP-specific and
IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; n=83;
Euteleostomi|Rep: High affinity cAMP-specific and
IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B - Homo
sapiens (Human)
Length = 885
Score = 124 bits (299), Expect = 3e-27
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 601 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 660
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 661 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 713
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 714 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 773
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 774 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 830
>UniRef50_Q005X2 Cluster: Phosphodiesterase 1; n=1;
Strongylocentrotus purpuratus|Rep: Phosphodiesterase 1 -
Strongylocentrotus purpuratus (Purple sea urchin)
Length = 680
Score = 124 bits (298), Expect = 4e-27
Identities = 72/223 (32%), Positives = 116/223 (52%), Gaps = 4/223 (1%)
Frame = +3
Query: 18 GKLFTLFESGYHST-NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHD 194
G E GY NPYHN +HA DVTQ +H L + + ++ +EI A LL+AI HD
Sbjct: 268 GAFLDAMELGYSKYGNPYHNLLHAADVTQTVHHMLARMGLVHWLSDLEIFASLLAAIIHD 327
Query: 195 IFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERP 365
H G F + T + +A Y + +VLE+HH ++ + + L
Sbjct: 328 FEHTGTTNAFHVNTKSDMAMFYN-------DRAVLENHHISSSFRLMRDDERNILANLSK 380
Query: 366 DLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADIS 545
+ EL+ + +++ATD++ + + K ++ T + + +++ L L CADIS
Sbjct: 381 EEYTELRNLVIDMVLATDMSFHFQQIKQMKSMISTTEA---LDKPKVMAL--TLHCADIS 435
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDST 674
+P + W KW+ + EFFRQGD E+ + LP++ LCDR+ST
Sbjct: 436 HPSKEWKFHYKWTTLLIREFFRQGDREREMGLPISPLCDRNST 478
>UniRef50_Q8I6Y6 Cluster: CGMP-specific phosphodiesterase; n=3;
Dictyostelium discoideum|Rep: CGMP-specific
phosphodiesterase - Dictyostelium discoideum (Slime
mold)
Length = 522
Score = 123 bits (297), Expect = 5e-27
Identities = 78/218 (35%), Positives = 122/218 (55%), Gaps = 5/218 (2%)
Frame = +3
Query: 30 TLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPG 209
++ S Y + NP+H+ HA VTQ + LL+ ++ + P+E ++ ++++I HD+ HP
Sbjct: 257 SIVASSYRN-NPFHSFNHAIAVTQTIFLILLKTNLFNILSPIEKLSIIIASICHDLDHPA 315
Query: 210 VNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEER-PDLQEELK 386
++ F I + +A LY N SVLE+HH L I+ES + E L E K
Sbjct: 316 LSNRFQINMKSSIAVLYN-------NKSVLENHHLSICLG-ILESKIGNELLSTLTVEEK 367
Query: 387 KH----LKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPC 554
K +K+LI+ATD+ Y +F ++ T + D EHR L+L + LK ADISN
Sbjct: 368 KQFFRRVKILILATDMENHFTYKKQFDDIISTFSWDN--SEHRDLLLIMFLKSADISNEL 425
Query: 555 RPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRD 668
R + +S KW+ + EEFF Q D EK+ +LP+T +R+
Sbjct: 426 RSFDISNKWANALMEEFFNQSDLEKLNNLPLTPFMERE 463
>UniRef50_Q22000 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-4; n=7; Caenorhabditis elegans|Rep: Probable
3',5'-cyclic phosphodiesterase pde-4 - Caenorhabditis
elegans
Length = 674
Score = 122 bits (295), Expect = 9e-27
Identities = 70/222 (31%), Positives = 118/222 (53%), Gaps = 11/222 (4%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
++ N YHN IHA DV Q+MH L+ + +E++A + + HD+ HPG +L
Sbjct: 400 HYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYL 459
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL-----LEERPDLQEELKKH 392
I + N LA +Y + SVLE HH A + +S L + LQ +K
Sbjct: 460 INSNNELAIMYN-------DESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQ--FRKI 510
Query: 393 LKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNPC 554
+ +++ATD+++ L+ K +++ N + + +I VLQ + AD+SNP
Sbjct: 511 VIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPT 570
Query: 555 RPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + Q+W+ ++ EE++RQGD EK L L ++ +CDR + +I
Sbjct: 571 KPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTI 612
>UniRef50_A2F9J4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1119
Score = 122 bits (293), Expect = 2e-26
Identities = 72/240 (30%), Positives = 122/240 (50%), Gaps = 4/240 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
++ PYHN HA DV Q + +++G +R ++ +EI A LL+AI HD+ H G+N F
Sbjct: 860 YNVTPYHNWTHACDVMQFVFSCIIRGHLRQYLNDLEIFALLLAAICHDVDHHGLNNAFHK 919
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEERPDLQEELK--KHLK 398
L LY E+ V+E HH A+ + E +LE ++ +
Sbjct: 920 KARTPLGILY-------EDKPVMEMHHCATAIRLLAMPEHDILEGIESYADKCHFYEFFI 972
Query: 399 VLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
+I+ATD+ + Y+ F+++ T D R ++HR+L+ QI +K D+SN R + +
Sbjct: 973 KIILATDMEKHMQYIKDFEEV--TKEFDKRNEKHRLLLAQIVIKAGDLSNTTRAFDTAAA 1030
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITEWNRFLDS 758
+ + EEFF+QGD E L + +T +CDR + + + + P +T +F+ S
Sbjct: 1031 MATNLMEEFFKQGDLESKLGVEITPMCDRSKATHISCSQVGFYGFCASPLLTALGKFITS 1090
>UniRef50_Q9W4T4 Cluster: cAMP-specific 3',5'-cyclic
phosphodiesterase, isoform I; n=38; Coelomata|Rep:
cAMP-specific 3',5'-cyclic phosphodiesterase, isoform I -
Drosophila melanogaster (Fruit fly)
Length = 1209
Score = 122 bits (293), Expect = 2e-26
Identities = 68/223 (30%), Positives = 118/223 (52%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E Y NP+HNS+HA DVTQ+ + L ++ P+E+ L +A HD+ HPG+
Sbjct: 861 EDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTN 920
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FL+ + + LA +Y + SVLE+HH A + G + ++ L+K
Sbjct: 921 QFLVNSSSELALMY-------NDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRK 973
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ ++++TD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 974 MVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNP 1033
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W + EEFF QGD E+ + ++ +CDR + +I
Sbjct: 1034 TKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATI 1076
>UniRef50_Q6S996 Cluster: Class I phosphodiesterase PDEB1; n=21;
Trypanosomatidae|Rep: Class I phosphodiesterase PDEB1 -
Leishmania major
Length = 940
Score = 121 bits (292), Expect = 2e-26
Identities = 70/208 (33%), Positives = 108/208 (51%), Gaps = 3/208 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN H DV Q +H +L G + +E L++A+ HD+ H GVN F + T +
Sbjct: 679 PYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDS 738
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGL-LEERPDLQEELKKHLKVL--IMA 413
L IL S N SVLE HH A+ + + + E Q+ + ++ ++A
Sbjct: 739 PLG----ILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQDVAYAYRALIDCVLA 794
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + D LSRF +L T+ + HR LV++ +K D+SN +P+ S+ W++ V
Sbjct: 795 TDMAKHADALSRFTELA-TSGFEKDNDTHRRLVMETLIKAGDVSNVTKPFETSRMWAMAV 853
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
EEF+RQGD EK + V + DR +
Sbjct: 854 TEEFYRQGDMEKEKGVEVLPMFDRSKNN 881
>UniRef50_Q8CFW8 Cluster: Phosphodiesterase 8B; n=13;
Euteleostomi|Rep: Phosphodiesterase 8B - Mus musculus
(Mouse)
Length = 730
Score = 120 bits (290), Expect = 4e-26
Identities = 72/235 (30%), Positives = 124/235 (52%), Gaps = 18/235 (7%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HPG
Sbjct: 448 VIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPGR 507
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE---- 380
FL + LA LY + +VLESHH ++ ++
Sbjct: 508 TNSFLCNAGSELAVLY-------NDTAVLESHHTALVFQLTVKDTKCNIFKNIDRNHYRT 560
Query: 381 LKKHLKVLIMATDITRQHDYLSRF-----KKL--------LDTNTLDMRIQEHRILVLQI 521
L++ + +++AT++T+ +++++F K L + N E++IL+ ++
Sbjct: 561 LRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAAESEGSDCECNPTGKNFPENQILIKRM 620
Query: 522 ALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
+KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 621 MIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 675
>UniRef50_A4RUJ3 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein -
Ostreococcus lucimarinus CCE9901
Length = 614
Score = 120 bits (290), Expect = 4e-26
Identities = 79/219 (36%), Positives = 121/219 (55%), Gaps = 8/219 (3%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
N YHN +HATDVTQA +L++ S+ + I P+ A L++A++HD+ HPGVN FL+
Sbjct: 352 NDYHNRVHATDVTQAA-AYLIETSLESQIEPIHTFAMLVAAMSHDVGHPGVNNTFLVNCK 410
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDL-QEELKKHLKVLIMAT 416
+ A+ + + SV E+ H A S + + +L + D Q +LKK L+ +IM T
Sbjct: 411 SAEAERWN-------DVSVNENGHLFTAFSLLKKHAVLAKFTDSEQSDLKKWLQKMIMYT 463
Query: 417 DITRQHDYLSRFKKLLD------TNTLDMRIQEHRILV-LQIALKCADISNPCRPWSVSQ 575
D+ + R K ++ TN++ Q I V L AL CADISNP RP+ ++
Sbjct: 464 DMEFHGELTQRMLKEIEDEQDEETNSIKPIKQWQNIWVPLAFALHCADISNPARPYELAL 523
Query: 576 KWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNT 692
W+ V EF++QGD ++ L + V DR S + P +T
Sbjct: 524 AWAQAVTAEFYKQGDRQRKLGMRVEPFMDR-SLAGPAST 561
>UniRef50_O18696 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-1; n=2; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-1 - Caenorhabditis elegans
Length = 664
Score = 120 bits (290), Expect = 4e-26
Identities = 75/218 (34%), Positives = 114/218 (52%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN +HA DVTQ+ H L Q + + +E++A L A+ HD H G
Sbjct: 322 EVGYSKHNNPYHNVVHAADVTQSSHFMLSQTGLANSLGDLELLAVLFGALIHDYEHTGHT 381
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I + + A LY + SVLE+HH + + E L D +EL+
Sbjct: 382 NNFHIQSQSQFAMLYN-------DRSVLENHHVSSCFRLMKEDDKNILTHLTRDEYKELR 434
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ +++ATD++ + K +L +L I +++ L L I C DIS+P +PW+
Sbjct: 435 NMVIEIVLATDMSTHFMQIKTMKSML---SLPEGIDKNKALCL-IVHAC-DISHPAKPWN 489
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ ++W+ V EEFFRQGD E + LP + LCDR + +
Sbjct: 490 LHERWTEGVLEEFFRQGDLEASMGLPYSPLCDRHTVHV 527
>UniRef50_A0DF61 Cluster: Chromosome undetermined scaffold_49, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_49, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 768
Score = 120 bits (289), Expect = 5e-26
Identities = 73/220 (33%), Positives = 117/220 (53%), Gaps = 3/220 (1%)
Frame = +3
Query: 18 GKLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDI 197
G+ ES Y + N YHNS+HA DV + F LQ + I + L+S++AHDI
Sbjct: 479 GEFSVKIESLYQN-NFYHNSMHAIDVANST-AFFLQNGLSTLIDDFQATCLLISSLAHDI 536
Query: 198 FHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL-LEERPDLQ 374
HPG+N GF+ A LA L+ + SVLE++H + +S + E +
Sbjct: 537 GHPGLNNGFMTANRCRLALLFN-------DQSVLENYHSFLLFQVLTQSNCNIIENLSIN 589
Query: 375 E--ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISN 548
E +K+ LI+ TD+TR +++F+ L+ N Q+ L++ I +KCAD+ +
Sbjct: 590 EIKGFRKYCLNLILDTDLTRHFQLMNKFQNYLNVNESPAVDQQ---LIMSIGIKCADVGH 646
Query: 549 PCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRD 668
+ + + WS ++ EEFF QGD E L +P++ +CDR+
Sbjct: 647 GAKELKLHKLWSRRIVEEFFLQGDLENYLKVPISPMCDRN 686
>UniRef50_Q14123 Cluster: Calcium/calmodulin-dependent 3',5'-cyclic
nucleotide phosphodiesterase 1C; n=128;
Euteleostomi|Rep: Calcium/calmodulin-dependent
3',5'-cyclic nucleotide phosphodiesterase 1C - Homo
sapiens (Human)
Length = 709
Score = 119 bits (287), Expect = 8e-26
Identities = 77/219 (35%), Positives = 110/219 (50%), Gaps = 5/219 (2%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN +HA DVTQ +H L + + ++ +EI A + SA HD H G
Sbjct: 217 EVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTT 276
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG----LLEERPDLQEEL 383
F I T + A LY + SVLE+HH AA + + L+ D E
Sbjct: 277 NNFHIQTRSDPAILYN-------DRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREF 329
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
+ + ++MATD++ + K L I++ + L L L ADIS+P + W
Sbjct: 330 RTLVIEMVMATDMSCHFQQIKAMKTALQQPEA---IEKPKALSLM--LHTADISHPAKAW 384
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 385 DLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMV 423
>UniRef50_Q23RI8 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Tetrahymena thermophila SB210
Length = 807
Score = 118 bits (285), Expect = 1e-25
Identities = 74/220 (33%), Positives = 118/220 (53%), Gaps = 5/220 (2%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIR--AFIRPVEIIACLLSAIAHDIFHP 206
L +GY N YHN +HA DVTQ MH F+ + A + +EI ++A AHD HP
Sbjct: 532 LVSNGYQD-NFYHNKMHAFDVTQTMHYFMQSLNFIGIADLSGLEIGLMYIAAAAHDYQHP 590
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQE 377
G N +LI T N LA Y + S LE+HH + + E + D +
Sbjct: 591 GFNNPYLINTRNELAIRYN-------DKSPLENHHAFSTFLLMQEENCNIFVHLTKDEFK 643
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
+ ++ + +I+ TD ++ L++ K L + D + ++ I ++ + L AD+SNP +
Sbjct: 644 KSRERIISMILHTDNSQHFADLAKLKGRLTSQDFDPKDKDKDICMMSL-LHSADVSNPYK 702
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
PW + ++W+ KV +EF+ QGD E+ LP+T LCDR +T+
Sbjct: 703 PWEICRQWTFKVLDEFWNQGDLERQSGLPITYLCDRFTTN 742
>UniRef50_A0EGK4 Cluster: Chromosome undetermined scaffold_95, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_95, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 756
Score = 118 bits (285), Expect = 1e-25
Identities = 80/267 (29%), Positives = 138/267 (51%), Gaps = 4/267 (1%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
KLFT YH+ N YHNS+HA DV + F L + A + E ++S++AHD+
Sbjct: 473 KLFTQ----YHN-NLYHNSLHALDVANST-AFFLNNGLDAQLDEFEFACLIVSSLAHDLG 526
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEER--PD 368
HPG+N GF+ LA LY + SVLE++H + + L++ PD
Sbjct: 527 HPGLNNGFMTTNRCKLALLYN-------DQSVLENYHSFLLFQILQQEQFNLIQNLGLPD 579
Query: 369 LQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISN 548
Q+ +K+ LI+ TD+T+ ++RF+ LD + + ++ + + LV+ I +KCAD+ +
Sbjct: 580 -QKGFRKYCLNLILDTDLTKHFQLMNRFQNYLDLS--ESQVTD-KSLVMSICIKCADVGH 635
Query: 549 PCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPX 728
+ + + WS ++ EEFF QGD E L +P++ +CDR + + L I LP
Sbjct: 636 GAKQLKMHKLWSRRIIEEFFLQGDLEDYLKVPISPMCDRKQSVVKSQEGFLKAIV--LPM 693
Query: 729 ITEWNRFLDSKLSXEMXANXXYNEVQW 809
+ + L ++ + + + +Q+
Sbjct: 694 FNAFAKLLQNEKVNSICLSQIHQNLQY 720
>UniRef50_Q388U6 Cluster: 3', 5'-cyclic nucleotide phosphodiesterase,
putative; n=2; Trypanosoma brucei|Rep: 3', 5'-cyclic
nucleotide phosphodiesterase, putative - Trypanosoma
brucei
Length = 620
Score = 117 bits (282), Expect = 3e-25
Identities = 77/242 (31%), Positives = 115/242 (47%), Gaps = 2/242 (0%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAF--IRPVEIIACLLSAIAHDIFHPGV 212
E GYH+ NPYHNS+HA DV H L +G + + +++A L +A HD HPG+
Sbjct: 362 EGGYHA-NPYHNSMHAADVLHITHYLLSKGGLAELCKLNDRQVLAALFAAAIHDYNHPGI 420
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKH 392
N F I T + A LY EN V + I + EE + +
Sbjct: 421 NNNFSILTQTYNATLYND-RSVLENMHVASVFELMRNPALNILACFSEEH---WRDFRNT 476
Query: 393 LKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVS 572
+ +++ATD++ Y+++FK+ L + L L +ALK ADISN CRP +
Sbjct: 477 VIDMVLATDMSLHEKYMTQFKRRLSEKRPFTEDCDQN-LALAMALKLADISNCCRPLPLY 535
Query: 573 QKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITEWNRFL 752
KWS +V +EF+ QGD E+ L + + DR + I + Y +P + FL
Sbjct: 536 LKWSERVSDEFYTQGDRERSLGMSCSPFMDRQTPMIAEGQTSFI-NYIFIPFLEVMAEFL 594
Query: 753 DS 758
S
Sbjct: 595 PS 596
>UniRef50_A2DJF3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1006
Score = 117 bits (282), Expect = 3e-25
Identities = 71/213 (33%), Positives = 110/213 (51%), Gaps = 5/213 (2%)
Frame = +3
Query: 42 SGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQG 221
S ++ PYHN HA DVTQ + L+ + ++P+E+ A L++AI HD+ H G
Sbjct: 748 SNSYNKVPYHNWRHAVDVTQFVSYQLVVSGVYKILKPIELYALLIAAICHDVNHDGFTNV 807
Query: 222 FLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKV 401
+ L L++ N SV+E+HH + A+ ++ + L K +
Sbjct: 808 YNEKAETPLGILFK-------NQSVMETHHCQVAIQ-VVSNDKCNIFSSFDSPLIKQIWS 859
Query: 402 LIMA----TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
LI+A TD+ + H L K LD L ++ R +++++ LKC+DISN RP+ +
Sbjct: 860 LIIALILKTDMGKHHSTLEAINKRLDEGPLKPDNEQDRFMMMELILKCSDISNVSRPFEL 919
Query: 570 SQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDR 665
+ KW +CEEFFRQGD EK + T L DR
Sbjct: 920 ADKWCDVLCEEFFRQGDLEKTSGMEYTSPLNDR 952
>UniRef50_Q6S998 Cluster: CAMP-specific phosphodiesterase; n=3;
Leishmania|Rep: CAMP-specific phosphodiesterase -
Leishmania major
Length = 631
Score = 117 bits (281), Expect = 4e-25
Identities = 75/219 (34%), Positives = 115/219 (52%), Gaps = 5/219 (2%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSI--RAFIRPVEIIACLLSAIAHDIFHPGV 212
E+ YH NPYHNS+HA DV Q + QG + R + +++ + LL+A HD HPG+
Sbjct: 376 EASYHG-NPYHNSMHAADVLQITDFIITQGGLAKRCDLSDIQVFSALLAASIHDFDHPGI 434
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQE-EL 383
N F I T ++LA LY + SVLE+ H + + +L D Q E+
Sbjct: 435 NNNFHIKTGSYLATLYN-------DRSVLENLHVSSVFELMKNPAFNILASFSDEQHHEV 487
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
++ + +++ATD+ Y++ K + ++ + E L L IALK ADISN RP
Sbjct: 488 RETMIEMVLATDMGSHGKYVASLKGKMQEHSSFTQTAEQN-LCLAIALKMADISNCGRPL 546
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W KV +EF++QGD E+ L L + DR S+
Sbjct: 547 DIYLRWGAKVSDEFYQQGDRERNLGLECSPFMDRLQPSL 585
>UniRef50_UPI000150A113 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 569
Score = 116 bits (279), Expect = 8e-25
Identities = 69/213 (32%), Positives = 113/213 (53%), Gaps = 6/213 (2%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAF--IRPVEIIACLLSAIAHDIFHPGVNQGFLIA 233
NPYHN IHA DVTQ MH FL + + + ++I ++A HD+ HPG N F +
Sbjct: 263 NPYHNKIHAFDVTQTMHFFLKKCNFVQIGKLNKIDIGTVFVAAAIHDVEHPGFNNPFQMN 322
Query: 234 TCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKV---- 401
LA LY + S LE+HH + ++ + + ++ K+++
Sbjct: 323 AKTDLAILYN-------DKSPLENHHLSVTFKLLRDNPSINIFEGIDKKTYKNVRETLIQ 375
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
+I+ TD+ + L++ K L +N D + + + L L L AD+SNP +P+ + Q+W
Sbjct: 376 MILKTDMNQHFTSLAQLKGRLASNEFDAKAAD-KPLCLNTLLHAADVSNPFKPFHIYQEW 434
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +V EF+ QGD E+ LP++ LCDR +T+I
Sbjct: 435 THRVLNEFWIQGDVERSRGLPISYLCDRYTTNI 467
>UniRef50_A2FBN7 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1090
Score = 116 bits (278), Expect = 1e-24
Identities = 74/216 (34%), Positives = 108/216 (50%), Gaps = 4/216 (1%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
YHST PYHN IHA DV Q + + G + EI A L++A+ HD H G N +
Sbjct: 827 YHST-PYHNWIHAVDVVQYVSYEMRLGELENIFTKFEIFAMLVAAVCHDAGHSGFNNIYN 885
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEE-RPDLQEELKKHLK 398
+ L L++ SV+E++H A+S + E L + Q+++ +
Sbjct: 886 VKAETPLGILFK-------EQSVMETYHCTVAISILTRKECNLFHSITEEAQKQMWTLII 938
Query: 399 VLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
LI+ATD+ + + +D + E R++ Q+ LK ADISN RP+ V+ K
Sbjct: 939 KLILATDMAFHFKMVKAATEFMDAGPFNPNDPEQRLIAFQLVLKTADISNVSRPFKVADK 998
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
W +CEEFFRQGD EK +T L DRD+ P
Sbjct: 999 WCDVLCEEFFRQGDKEKAQAFGLTSPLNDRDNPDKP 1034
>UniRef50_A4RV03 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein -
Ostreococcus lucimarinus CCE9901
Length = 401
Score = 115 bits (277), Expect = 1e-24
Identities = 69/222 (31%), Positives = 116/222 (52%), Gaps = 10/222 (4%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
G + NPYH HA DVT + ++ + + VEI + L++A+ HD+ HPGV G+
Sbjct: 63 GMYRDNPYHCFKHAVDVTHTTYLYICAVKEQVSMTQVEIFSLLVAALVHDLDHPGVTNGY 122
Query: 225 LIATCNHLADLYR---ILEGT--SENFSVLESHHWRAALSCIIESGLLEERPD-----LQ 374
LIAT +++A Y +LE S FS+ +++ LS ES E R L
Sbjct: 123 LIATHDNIALTYNDESVLENLHLSRFFSLCQNNEDANILSAFDESTYKEIRRSIISCVLH 182
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPC 554
++ H K++ ++ L + +++ + + + R L+L + L CADISN
Sbjct: 183 TDMAHHFKLVSRLNELVA----LGKKNNIINGSPMKSTTDDERQLMLNVLLHCADISNAV 238
Query: 555 RPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + KW+ +V EEFF QGD E+ + ++ + DR++TS+
Sbjct: 239 KPNELCVKWASRVLEEFFNQGDRERSRGMSISPMMDRETTSV 280
>UniRef50_Q4D500 Cluster: Phosphodiesterase, putative; n=3;
Trypanosoma cruzi|Rep: Phosphodiesterase, putative -
Trypanosoma cruzi
Length = 708
Score = 115 bits (276), Expect = 2e-24
Identities = 73/214 (34%), Positives = 116/214 (54%), Gaps = 5/214 (2%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSI--RAFIRPVEIIACLLSAIAHDIFHPGV 212
E+GY+ NPYHNS+HA DV H L +G + R + +++ A L +A HD HPGV
Sbjct: 453 EAGYNG-NPYHNSMHAADVLHITHYILSKGGMIERCQLSDLQVFAALFAAAIHDYNHPGV 511
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEE-RPDLQEEL 383
N F I T + A +Y + SVLE+ H + + +LE D Q+E+
Sbjct: 512 NNNFHIKTQTYSAIVYN-------DRSVLENAHVSSVFELMKNPRFNILESFSEDQQKEI 564
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
++ + +++ATD++ +++ F L+ + +E++ L L +ALK ADISN RP
Sbjct: 565 RETVIEMVLATDMSLHGKHIAHFNDRLEEHA-SFTERENQNLALVMALKMADISNCGRPL 623
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDR 665
+ KWS K+ +EF+ QGD E+ L + + DR
Sbjct: 624 EIYLKWSSKLSDEFYLQGDRERNLGVQCSPFMDR 657
>UniRef50_A2DNV4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1023
Score = 115 bits (276), Expect = 2e-24
Identities = 73/221 (33%), Positives = 110/221 (49%), Gaps = 6/221 (2%)
Frame = +3
Query: 21 KLFTLFESGYHSTN--PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHD 194
K F+ S N PYHN HA DVTQ + ++ G I + E+ L++ I HD
Sbjct: 759 KFFSFLTEVSESYNKVPYHNRRHAVDVTQFVAYEIIIGKIDKILTKEELFCLLIACICHD 818
Query: 195 IFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIE--SGLLEERPD 368
I H G + + L L++ N SV+E+HH + + S +
Sbjct: 819 INHDGFTNVYNVKAETPLGILFK-------NQSVMETHHCEVTIGIMTNEMSNVFACFEG 871
Query: 369 LQ-EELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADIS 545
Q ++ + L LI+ TD+ + + +F +LLD LD ++R+ ++QI LKC DIS
Sbjct: 872 QQYSKMWQMLFTLILGTDMFHHYTIIKQFNELLDKGPLDYSDDQNRLKLMQILLKCGDIS 931
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT-QLCDR 665
N RP+ ++ KW +CEEFFRQGD E+ + T L DR
Sbjct: 932 NVSRPFKIADKWCDVLCEEFFRQGDLEQAQGMEYTSNLNDR 972
>UniRef50_A2DF08 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1040
Score = 114 bits (275), Expect = 2e-24
Identities = 65/191 (34%), Positives = 101/191 (52%), Gaps = 3/191 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA DVTQ + LL+ + E+ A L+SA+ HD H G + +
Sbjct: 785 PYHNWRHAVDVTQFVVYELLESGCDKVLTKFEVFALLVSAVCHDANHDGFTNVYNVKAET 844
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCII-ESGLLEERPDLQEELKKHLKV--LIMA 413
L L++ N SV+E+HH + A+ I E + + + + + LI++
Sbjct: 845 PLGILFK-------NQSVMETHHCQVAIGVISKEECNIFSALNAGDNRTMWMTIISLILS 897
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + + L F ++D M ++HRIL++Q+ LK ADISN RP+ ++ +W +
Sbjct: 898 TDMAKHFEILKNFNAIMDAGEFSMENKDHRILLMQLLLKTADISNVSRPFDIANRWCDIL 957
Query: 594 CEEFFRQGDYE 626
CEEFFRQGD E
Sbjct: 958 CEEFFRQGDLE 968
>UniRef50_A2ERL4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1180
Score = 114 bits (274), Expect = 3e-24
Identities = 69/205 (33%), Positives = 105/205 (51%), Gaps = 4/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA DVTQ + ++ + E+ + +++AI HD H G + +
Sbjct: 811 PYHNWRHAVDVTQFVTYQIMISGLEKVFTKFELFSLVVAAICHDANHDGFTNIYNVKAET 870
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEE-RPDLQEELKKHLKVLIMA 413
L LY+ N SV+E+HH A+ + E+ LL D E+ + I+A
Sbjct: 871 PLGILYK-------NQSVMETHHCSIAIQIMSHEETNLLAALNQDEYIEIWSLIIQYILA 923
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ R + L RF + D M+ +HR+++L + LKC DISN RP+ ++ +W +
Sbjct: 924 TDMARHFEILKRFNDIYDGGDFTMQRHDHRVMLLYMILKCGDISNVSRPFELADRWCDVL 983
Query: 594 CEEFFRQGDYEKMLDLPVT-QLCDR 665
CEEFFRQGD E+ + T L DR
Sbjct: 984 CEEFFRQGDLEQAQGMAYTSDLNDR 1008
>UniRef50_A2D762 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1081
Score = 114 bits (274), Expect = 3e-24
Identities = 70/211 (33%), Positives = 110/211 (52%), Gaps = 4/211 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN +H DV Q + + + +P+E++A ++A+ HD H G+N + +
Sbjct: 829 PYHNWMHCVDVCQYLAYEVSTAELDKVYKPLELLAMFVAAVCHDAGHEGLNNIYNVKAET 888
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCII-ESGLLEERPDL--QEELKKHLKVLIMA 413
L L++ + SV+E+HH A+S + E L DL Q +L + LI+A
Sbjct: 889 PLGILFK-------DQSVMETHHCTVAISLLTKEEYNLFHSVDLEHQRQLWTTIIQLILA 941
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + ++ D D+ EHR+L +++ LK DISN RP+ ++ KW +
Sbjct: 942 TDMANHFKLVKDTNEIADKAEFDIEKPEHRLLSMKLLLKVGDISNVSRPFQIADKWCDIL 1001
Query: 594 CEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
CEEFFRQGD EK L + +T L DR + P
Sbjct: 1002 CEEFFRQGDNEKSLGIGLTSPLNDRLNNDKP 1032
>UniRef50_UPI00006CBCA5 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 649
Score = 113 bits (273), Expect = 4e-24
Identities = 69/222 (31%), Positives = 115/222 (51%), Gaps = 5/222 (2%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIR--AFIRPVEIIACLLSAIAHDIF 200
F E GY+ N YHN +HA DV Q + FL + A I ++ +SA HD
Sbjct: 370 FKQIEKGYND-NLYHNRLHAFDVLQTANFFLKSCNFIEIAAINEFDLCTIYISAACHDYD 428
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE 380
HPGVN F+I T + +A Y + SVLE+HH + L +E+
Sbjct: 429 HPGVNNAFIINTSHEIALTYN-------DQSVLENHHASKTFQLFNDQNLDITANFTKEQ 481
Query: 381 LKKHLKV---LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNP 551
+ ++ +I++TD+ + +++ K L T+ D++ ++ ++ + I C D+SNP
Sbjct: 482 YRSFREMVISIILSTDMAKHFSDIAKLKSRLGTDDYDIKGKDKQMCIDTIIHAC-DVSNP 540
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ W+V Q+W+ +V EF+ QGD E+ + +T LCDR +T+
Sbjct: 541 VKTWNVYQQWAHRVLSEFWSQGDQERSQGIQITYLCDRYTTN 582
>UniRef50_Q57V52 Cluster: 3', 5'-cyclic nucleotide phosphodiesterase,
putative; n=3; Trypanosoma|Rep: 3', 5'-cyclic nucleotide
phosphodiesterase, putative - Trypanosoma brucei
Length = 676
Score = 113 bits (273), Expect = 4e-24
Identities = 70/218 (32%), Positives = 117/218 (53%), Gaps = 6/218 (2%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMH--CFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+SGYH NPYHNS+HA DVTQ + F+ R +RP E + +L+A HD HPG+
Sbjct: 422 QSGYHP-NPYHNSMHAADVTQVNYYIIFIAGMKERCQLRPEEQLGAVLAAAVHDFDHPGL 480
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQ-EEL 383
N F T +L+ LY + S+LE+HH + + +L D Q +
Sbjct: 481 NNNFHTRTNAYLSTLY-------NDRSILENHHIASVFQLLKHPSYNVLAPLNDEQFRTV 533
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILV-LQIALKCADISNPCRP 560
++ + +++ATD++ L RF+ L D + +LV L +++K AD+SN RP
Sbjct: 534 RETMVEMVLATDMSNHGTILKRFQSRL-VEASDWSANKQDVLVALSMSIKTADLSNCIRP 592
Query: 561 WSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDST 674
+ + +WS + +EF++QGD E+ +L ++ +R ++
Sbjct: 593 YYIYSEWSSYIAQEFYKQGDEEERSNLSISPFMNRKTS 630
>UniRef50_A0CB76 Cluster: Chromosome undetermined scaffold_163,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_163,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 619
Score = 113 bits (272), Expect = 5e-24
Identities = 74/215 (34%), Positives = 109/215 (50%), Gaps = 4/215 (1%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAF--IRPVEIIACLLSAIAHDIFHPGVNQG 221
YH N YHN IHA DVT ++ F+ + + + + ++ L+SA AHD HPG+N
Sbjct: 360 YHKDNLYHNVIHAFDVTHTVYFFIQKCNFKEIGKLTKIDYSILLMSAAAHDADHPGLNNI 419
Query: 222 FLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEE--RPDLQEELKKHL 395
FL T + LA Y + S LE HH I E+ LL D + +K +
Sbjct: 420 FLSNTRHDLAMTYN-------DKSPLEQHHAATLFRYIRETDLLVHFTLQDFKYFREKSI 472
Query: 396 KVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQ 575
+++ + DY ++ K L +N D ++ I L ADISNP +P +
Sbjct: 473 NMILSTDNAMHGKDY-NKLKARLASNDFDPGSKDKGIC-FDTLLHAADISNPFKPMKNYE 530
Query: 576 KWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+W+ +V EF+ QGD EK L LPVT LCDR +T++
Sbjct: 531 QWTFRVLGEFWHQGDREKELGLPVTMLCDRRTTNV 565
>UniRef50_A7RXZ4 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 367
Score = 89.8 bits (213), Expect(2) = 6e-24
Identities = 57/189 (30%), Positives = 91/189 (48%), Gaps = 4/189 (2%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G++ I +E+++ +A HD HPG FL+AT +H A LY + SVLE+
Sbjct: 148 GALVDVIPLLELLSLYTAAAMHDYDHPGRTNAFLVATLSHQALLYN-------DRSVLEN 200
Query: 306 HHWRAALSCIIESGLLEERPDLQEELKKHLKVL----IMATDITRQHDYLSRFKKLLDTN 473
HH AA + ++ +L K + L I+ATD+ R D LS F
Sbjct: 201 HHAAAAFTLLMSDPKYNFLCELSPAEFKRFRFLAIEAILATDLKRHFDILSDFNAKTAEG 260
Query: 474 TLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ 653
++ + R+L LQ +K +DIS P + + W+ ++ EEF+ QGD E+ + V+
Sbjct: 261 GVNWDSEADRLLTLQFCIKMSDISGPSKRRDIHTLWTERIVEEFYEQGDDERARGMAVSP 320
Query: 654 LCDRDSTSI 680
DR +
Sbjct: 321 YMDRQQPHV 329
Score = 44.4 bits (100), Expect(2) = 6e-24
Identities = 23/42 (54%), Positives = 26/42 (61%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRP 152
F ESGYHS PYHNSIHA+DV Q ++ FL I F P
Sbjct: 68 FFALESGYHSI-PYHNSIHASDVLQGVY-FLTTAKIPGFCPP 107
>UniRef50_A7SVS5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 496
Score = 112 bits (270), Expect = 9e-24
Identities = 71/221 (32%), Positives = 115/221 (52%), Gaps = 4/221 (1%)
Frame = +3
Query: 33 LFESGYH-STNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPG 209
LFE H + P+HN HA VTQ M+ + I I +++ L SA+ HD+ HPG
Sbjct: 212 LFEVYRHYNPTPFHNFRHAFCVTQMMYGLIWLTEIFNKITKQDLLIMLTSALCHDLDHPG 271
Query: 210 VNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIE--SGLLEE-RPDLQEE 380
N + I LA Y + S LE+HH A + + S +L+ + ++
Sbjct: 272 YNNAYQINARTELALRYN-------DISPLENHHCAVAFDIMKQDKSNILQNVSAETFKK 324
Query: 381 LKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRP 560
+++ + I++TD+ R D L++FK+LL + + H+ +++QI +K +D+SN RP
Sbjct: 325 IREGMIKCILSTDMARHSDILNKFKELLKSG-FKFDDEAHKSMLMQIMIKVSDVSNEARP 383
Query: 561 WSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
V++ W + +EFF Q D EK+ LPV DRD + P
Sbjct: 384 MDVAEPWLDCLLQEFFIQSDVEKLEGLPVAPFMDRDKVTKP 424
>UniRef50_Q6NNF2 Cluster: SD02170p; n=9; Diptera|Rep: SD02170p -
Drosophila melanogaster (Fruit fly)
Length = 914
Score = 111 bits (268), Expect = 2e-23
Identities = 78/252 (30%), Positives = 125/252 (49%), Gaps = 11/252 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFI--RPVEIIACLLSAIAHDIFHP 206
+ E+ Y +N YHNS HA DV QA F+ Q + + + +E L++A AHD+ HP
Sbjct: 628 VIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHP 687
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELK 386
G + FL + + LA LY L +VLE+HH + + +L +E
Sbjct: 688 GRSSAFLCNSNDALAVLYNDL-------TVLENHHAAITFKLTLGDDKINIFKNLDKETY 740
Query: 387 KHLKV----LIMATDITRQHDYLSRFKKLLD-TNTLDMRIQ---EHRILVLQIALKCADI 542
K + +I+AT++TR ++L++F + D Q E IL+ ++ +K AD+
Sbjct: 741 KSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNPQTDEETSILMRRMLIKVADV 800
Query: 543 SNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIPXNTNXLL*IYXS 719
SNP RP +W+ ++ EE+F Q D EK LP+ + DR + SIP + + Y
Sbjct: 801 SNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFI-EYII 859
Query: 720 LPXITEWNRFLD 755
+ W F+D
Sbjct: 860 QDMMHAWESFID 871
>UniRef50_O76083 Cluster: High affinity cGMP-specific 3',5'-cyclic
phosphodiesterase 9A; n=62; Eumetazoa|Rep: High affinity
cGMP-specific 3',5'-cyclic phosphodiesterase 9A - Homo
sapiens (Human)
Length = 593
Score = 111 bits (268), Expect = 2e-23
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 306 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 365
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 366 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 418
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 419 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 476
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 477 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 508
>UniRef50_A5K0J4 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=5; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 1001
Score = 111 bits (267), Expect = 2e-23
Identities = 76/268 (28%), Positives = 128/268 (47%), Gaps = 4/268 (1%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
K F L ++ PYHNS+HA V L I I ++ +S++ HD+
Sbjct: 711 KNFLLKMHSLYNDVPYHNSLHAAQVAHFSKSMLFLLDINHKIPAIDEFCLHVSSLCHDVG 770
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERP-DL 371
HPG+N FLI + N+LA Y ++N SVLE++H + E + E P ++
Sbjct: 771 HPGLNNYFLINSENNLALTY------NDN-SVLENYHCSLVFKTLKEKNCNIFENYPYNI 823
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNP 551
KK++ I++TD+ +Y+S F+ + LD+ + + + LK ADI +
Sbjct: 824 FTTCKKNIIRAILSTDMKNHFEYISNFRTSKEFIDLDILTSDQTWQIFSLILKAADIGHA 883
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXI 731
W+ +W++K+ EEF+ QG EK L++P + LCD +S N+ + +P
Sbjct: 884 TLDWNKHYEWTMKINEEFYLQGLLEKSLNMPNSFLCDINSIDKLANSQIGFLKHLCIPLF 943
Query: 732 TEWNRF-LDSKLSXEMXANXXYNEVQWE 812
+E N + ++ + N QWE
Sbjct: 944 SELNSISRNDEVYNHCICSIENNIEQWE 971
>UniRef50_UPI000065D378 Cluster: cAMP-specific 3',5'-cyclic
phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).; n=4;
Euteleostomi|Rep: cAMP-specific 3',5'-cyclic
phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46). -
Takifugu rubripes
Length = 715
Score = 111 bits (266), Expect = 3e-23
Identities = 72/244 (29%), Positives = 124/244 (50%), Gaps = 30/244 (12%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DVTQ+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 392 EDHYHANVAYHNSLHAADVTQSTHVLLSTPALDAVFTDLEILAALFAAAIHDVDHPGVSN 451
Query: 219 GFLIATCN---------------HLADLYRIL-EGTSENFSVLESHHWRAALSCIIESGL 350
FLI T + HLA +++L E + F L ++ +I+
Sbjct: 452 QFLINTNSELALMYNDESVLENHHLAVGFKLLHEDNCDIFQNLSKRQRQSLRKLVIDMAS 511
Query: 351 LEER--------PDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLD---MRIQE 497
+ P + ++ATD+++ L+ K +++T + + + +
Sbjct: 512 VRSSFTFTYLRIPAPHTDCSGLSCPQVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLD 571
Query: 498 H---RILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRD 668
H RI VL+ + CAD+SNP +P +V ++W+ ++ EEFFRQGD E+ + ++ +CD+
Sbjct: 572 HYTDRIQVLRNLVHCADLSNPTKPLAVYRQWTERIMEEFFRQGDKERERGMEISPMCDKH 631
Query: 669 STSI 680
+ S+
Sbjct: 632 TASV 635
>UniRef50_Q01CI7 Cluster: Cyclic GMP phosphodiesterase; n=1;
Ostreococcus tauri|Rep: Cyclic GMP phosphodiesterase -
Ostreococcus tauri
Length = 526
Score = 111 bits (266), Expect = 3e-23
Identities = 69/210 (32%), Positives = 112/210 (53%), Gaps = 8/210 (3%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
N YHN +HA DVTQA + ++ S+R I P+ I A LLSA+ HD+ HPG+N +L+A
Sbjct: 261 NDYHNGVHAADVTQAA-AYFIETSLRDQIEPIHIFALLLSAVVHDVGHPGLNNAYLVARQ 319
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELK-KHLKVLIMAT 416
+A+ + N SV E+ H A + + + +L++ D L K L+ +++ T
Sbjct: 320 TDVAERWN-------NVSVNENGHLYTANTLLKQYDVLKDFADDDRVLVLKLLQKMVLCT 372
Query: 417 DITRQHDYLSRFKKLLDTNT-----LDMRIQE--HRILVLQIALKCADISNPCRPWSVSQ 575
D+ D + + + ++ L ++E + L AL CADISNP RP+ ++
Sbjct: 373 DMEVHADLVKKVIEAVEREFDKEAGLLKPVKEWGEVWIPLAFALHCADISNPARPYDLAL 432
Query: 576 KWSVKVCEEFFRQGDYEKMLDLPVTQLCDR 665
W+ + EEFF+QGD ++ + V DR
Sbjct: 433 YWANAIVEEFFKQGDLQRGFQMSVPGFMDR 462
>UniRef50_A2DYU6 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1091
Score = 110 bits (265), Expect = 4e-23
Identities = 68/211 (32%), Positives = 107/211 (50%), Gaps = 4/211 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN +HA DVT+ + L + P+E A LLSA+ HD H G N F I
Sbjct: 819 PYHNWMHACDVTEYVAYELKTSGFDEMLSPLEKFALLLSAVCHDANHEGFNNIFNIKAQT 878
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVLI---MA 413
L L++ + SV+E+HH ++ + + +E+ KK +++I +A
Sbjct: 879 PLGLLFK-------DTSVMETHHLTVSIDILSDDSYNLIYSLSEEDTKKMWQMMIQNILA 931
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + + + K L+D D+ +EHR + + + LK ADISN RP+ ++ W +
Sbjct: 932 TDMAKHFEMIKTTKALVDAGEFDLNKEEHRRIAMSLLLKVADISNVSRPFELADNWCDIL 991
Query: 594 CEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
EF+RQGD EK + +T L DR+ P
Sbjct: 992 NVEFYRQGDLEKATGIGLTSPLNDREHPDKP 1022
>UniRef50_A2DG30 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1090
Score = 110 bits (265), Expect = 4e-23
Identities = 67/198 (33%), Positives = 99/198 (50%), Gaps = 3/198 (1%)
Frame = +3
Query: 42 SGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQG 221
+GY PYHN HA DV Q + + I VE+ A L++AI HD+ H G
Sbjct: 771 AGYRPV-PYHNWAHAVDVLQFTAYQVHISHLDEKIPKVELFALLVAAICHDLNHDGFTND 829
Query: 222 FLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEERPDLQEELKKHL 395
+ + L L++ N SV+E HH + + + L P Q + +L
Sbjct: 830 YNVKAETPLGILFK-------NQSVMEMHHCEVTIDIMSNDQCNLFSALPPQQFKQVWNL 882
Query: 396 KV-LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVS 572
+ LI+ATD+ + L F L+D T M + HR L+LQ+ +K D+SN RP+ ++
Sbjct: 883 VINLILATDMAKHFTILQEFNTLIDGKTFSMENENHRHLLLQLIIKVGDLSNVSRPFDLA 942
Query: 573 QKWSVKVCEEFFRQGDYE 626
+W +CEEFFRQGD E
Sbjct: 943 NRWCAVLCEEFFRQGDLE 960
>UniRef50_Q4KL87 Cluster: MGC116558 protein; n=2; Xenopus|Rep:
MGC116558 protein - Xenopus laevis (African clawed frog)
Length = 342
Score = 109 bits (263), Expect = 7e-23
Identities = 65/210 (30%), Positives = 107/210 (50%), Gaps = 3/210 (1%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
++ NP+HN H VTQ M+C + Q ++ + ++I+ +++A+ HD+ HPG++ +
Sbjct: 84 HYQENPFHNFYHGFSVTQMMYCVISQCQLQEHLSHIDILTLMVAALCHDLDHPGLSNSYQ 143
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAA---LSCIIESGLLEERPDLQEELKKHLK 398
+ LA Y N S LE+HHW A LS + LL P +++ +
Sbjct: 144 VNAQTDLARQY-------HNKSPLENHHWAVAWRILSQKQSNLLLGADPKQVPHIQQEIM 196
Query: 399 VLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
LI+ATD+ + L + + + N + +EH + + +K DISN RP ++
Sbjct: 197 ELILATDMAHHGEILQTLQNIENFNFSN---REHVTALKKGLIKICDISNEARPAEQAEI 253
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQLCDRD 668
W+ + EE+F Q D EK LPVT DRD
Sbjct: 254 WADALMEEYFLQSDREKDEGLPVTPYMDRD 283
>UniRef50_Q4SP32 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 15
SCAF14542, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 763
Score = 106 bits (255), Expect = 6e-22
Identities = 69/242 (28%), Positives = 123/242 (50%), Gaps = 28/242 (11%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
ES YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 433 ESHYHSNVAYHNSLHAADVAQSTHILLSTPALNAVFTDLEILAAIFAAAIHDVDHPGVSN 492
Query: 219 GFLIATCNHLADLYR---ILEG--TSENFSVLESHHW----------RAALSCIIESGLL 353
FLI T + LA +Y +LE + F +L+ + R L ++ +
Sbjct: 493 QFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLTKKQRQTLRRMVIDMVR 552
Query: 354 EERPDLQEELKKHLKVL-------IMATDITRQHDYLSRFKKLLDTNTLD----MRIQEH 500
R Q + ++ATD+++ L+ K +++T + + + +
Sbjct: 553 AARARAQGSRARFPSATLRWSPHQVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNY 612
Query: 501 --RILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDST 674
R+ VL+ + CAD+SNP +P + ++W+ ++ +EFF QGD E+ + ++ +CD+ +
Sbjct: 613 TDRMQVLRNMVHCADLSNPTKPLDLYRQWTDRIMDEFFHQGDRERERGMEISPMCDKHTA 672
Query: 675 SI 680
S+
Sbjct: 673 SV 674
>UniRef50_Q4RH59 Cluster: Chromosome undetermined SCAF15069, whole
genome shotgun sequence; n=3; Euteleostomi|Rep:
Chromosome undetermined SCAF15069, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 695
Score = 106 bits (254), Expect = 8e-22
Identities = 78/234 (33%), Positives = 112/234 (47%), Gaps = 20/234 (8%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H LL+ + ++ +EI A + +A HD H G
Sbjct: 274 EVGYSKHKNPYHNLIHAADVTQTVHYLLLKTGMVHWLTELEIFAMIFAAAVHDYEHTGTT 333
Query: 216 QGFLIAT-------CNHLADLYR-----ILEGTS---ENFSVLESHHWRAALSCIIESGL 350
F I T C L + I T+ + SVLESHH AA + +
Sbjct: 334 NNFHIQTSSAKYTSCICPVQLQQDPKNEIKSDTAILYNDRSVLESHHVSAAYRLLQDDDE 393
Query: 351 LEERPDLQEELKKHLKVLI----MATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQ 518
+ +L ++ + L+ L+ +ATD++ + K L I + + L
Sbjct: 394 MNILYNLSKDDWRELRALVVEMVLATDMSCHFQQVKAMKNFLQQPE---GIDKPK--ALS 448
Query: 519 IALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ L ADIS+P + W + W+ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 449 LLLHTADISHPAKNWDLHHHWTTSLLEEFFRQGDKEADLGLPFSPLCDRKSTMV 502
>UniRef50_A3FQ29 Cluster: CGMP phosphodiesterase A4; n=2;
Cryptosporidium|Rep: CGMP phosphodiesterase A4 -
Cryptosporidium parvum Iowa II
Length = 997
Score = 105 bits (252), Expect = 1e-21
Identities = 63/212 (29%), Positives = 108/212 (50%), Gaps = 4/212 (1%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
N YHN +H T+V C + + + VE +A +++++ HD+ H G FL+ +
Sbjct: 722 NKYHNELHGTNVCHLAICLSRATGLWSHLDTVERLASVIASLGHDVGHIGRTSNFLVNSR 781
Query: 240 NHLADLYR---ILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVLIM 410
+ LA Y +LE + + +++ + ++S E L +E ++ + LI+
Sbjct: 782 HMLAINYNDRSVLEMFHASLTFRIIYYYGGGAADFLQSWDAE----LHKEFRRIVIELIL 837
Query: 411 ATDITRQHDYLSRFKKLLDTNTLD-MRIQEHRILVLQIALKCADISNPCRPWSVSQKWSV 587
TD+ R + +SRF+ D + R+++ + LK ADI + W+ KW
Sbjct: 838 ETDMHRHFECVSRFRVRRQAVDWDPYGDAQDRLMLARTCLKAADIGHGALKWNQHYKWCR 897
Query: 588 KVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
V EEFF QGD EK L LP++ +CDR+ST +P
Sbjct: 898 SVVEEFFLQGDEEKALSLPISPICDRESTDVP 929
>UniRef50_A2ENJ2 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1087
Score = 105 bits (252), Expect = 1e-21
Identities = 69/211 (32%), Positives = 106/211 (50%), Gaps = 4/211 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA DVTQ + L I + + +I A L++AI HD H G + +
Sbjct: 831 PYHNWRHAVDVTQYVTFELETSGIVSKLTKFDIFALLVAAICHDANHDGFTNVYNVKAET 890
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEE-RPDLQEELKKHLKVLIMA 413
L L++ N SV+E+HH A+S I E+ + + + +++ + LI+A
Sbjct: 891 PLGILFK-------NQSVMETHHCAMAISVISKEETNIFAKLNAEQYKKIWTTIINLILA 943
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +L ++D L + + L++ LKCADISN RP+ ++ KW +
Sbjct: 944 TDMAKHFTFLKEINGIMDEGKLSIDNPDDVSYYLELILKCADISNVSRPFELADKWCDVL 1003
Query: 594 CEEFFRQGDYEKMLDLPVT-QLCDRDSTSIP 683
CEEFFRQGD E + T L DR + P
Sbjct: 1004 CEEFFRQGDLEMAQGMQYTSDLNDRSHLNKP 1034
>UniRef50_A2E8N2 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1103
Score = 105 bits (251), Expect = 2e-21
Identities = 73/211 (34%), Positives = 107/211 (50%), Gaps = 4/211 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA DVTQ M L + + P EI+A L++ I HD H G N + N
Sbjct: 821 PYHNWTHAVDVTQFMVYQLEKAELSKVFSPFEILAILVATICHDANHNGFNNQY-----N 875
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVLI---MA 413
A L L ++ SVLE +H A+ I + +E++ + ++I A
Sbjct: 876 EKAQLP--LGILFKDMSVLEVYHCTVAIGIISKEKTNIFTGIPEEDIPRIWTIIIHMIKA 933
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + + ++LLD+ DM R+L +Q+ LK +DISN RP+ + KW +
Sbjct: 934 TDMKLHFSIVQKAQELLDSGKFDMNDPACRLLSMQLLLKVSDISNVSRPFDFANKWCDIL 993
Query: 594 CEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
EEFFRQGD EK L L ++ L DR++ P
Sbjct: 994 NEEFFRQGDNEKKLGLGLSSPLNDRENADKP 1024
>UniRef50_A2EIP4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1334
Score = 103 bits (247), Expect = 6e-21
Identities = 65/206 (31%), Positives = 103/206 (50%), Gaps = 5/206 (2%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA DV Q + +L + EI A L++ + HD+ H G F
Sbjct: 1083 PYHNWRHAVDVMQFVAYQILVSGCNTILSKFEIFAILVACLCHDVGHDGFTNAFNEKAET 1142
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEE-RPDLQEELKKHLKVLIMA 413
L L++ N SV+E+HH ++ + E + + +P+ + + + LI+A
Sbjct: 1143 PLGLLFK-------NQSVMETHHCSVSIGILSKEECNIFSKLQPNEYKNMWILIIRLILA 1195
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEH-RILVLQIALKCADISNPCRPWSVSQKWSVK 590
TD+ + D L + +D D++ E+ R L+I +KC D+SN RP+ ++ KW
Sbjct: 1196 TDMAKHFDILKDINQRVDNGEFDLQKNENDRYSFLEILIKCGDVSNVSRPFELANKWCDV 1255
Query: 591 VCEEFFRQGDYEKMLDLPVTQ-LCDR 665
+CEEFFRQGD E+ + T L DR
Sbjct: 1256 LCEEFFRQGDLEQASGMEYTSPLNDR 1281
>UniRef50_UPI00015B464B Cluster: PREDICTED: similar to
ENSANGP00000010843; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010843 - Nasonia
vitripennis
Length = 801
Score = 102 bits (244), Expect = 1e-20
Identities = 63/207 (30%), Positives = 103/207 (49%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
P+HN H V Q ++ + ++ I +E++ ++S I HD+ HPG N + I
Sbjct: 545 PFHNFRHCFCVAQMLYIITGSVNTKSRIGDLEVLVLIVSCICHDLDHPGYNNIYQINART 604
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVLIMATDI 422
LA Y + EN + H A C I + L +P+ +++ + I+ATD+
Sbjct: 605 ELALRYNDISPL-ENHHCSVAFHILEAPECNILASL---QPETYRIVREGIIRCILATDM 660
Query: 423 TRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEE 602
R ++ L++F + D + H L+ + +K ADISN RP V++ W + +E
Sbjct: 661 ARHNEILAQFTDAVPD--FDYSSKVHINLLSMVLIKVADISNEARPMDVAEPWLDSLLQE 718
Query: 603 FFRQGDYEKMLDLPVTQLCDRDSTSIP 683
FF+Q D EK+ LPVT DRD + P
Sbjct: 719 FFKQSDAEKLEGLPVTPFMDRDKVTKP 745
>UniRef50_A2FQ29 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1175
Score = 102 bits (244), Expect = 1e-20
Identities = 68/212 (32%), Positives = 108/212 (50%), Gaps = 4/212 (1%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY+ PYHN +HA DV Q L + + + I EI+ ++S + HDI H G + +
Sbjct: 899 GYNPV-PYHNFLHAVDVMQFAVYLLKKSKLESEISKFEILGLIISCLCHDINHDGFSNSY 957
Query: 225 LIATCNHLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEERPDLQEELKKHLK 398
L LY+ N SVLE+HH +S + + LL+ + +L
Sbjct: 958 NEKAQTPLGILYK-------NQSVLETHHCSVCISIMTREDCNLLKSLNISDTQKMWNLI 1010
Query: 399 V-LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQ 575
+ LI+ TD+ + ++L K+++ D R Q R +LQ+ +K +DIS R + ++
Sbjct: 1011 INLILITDMAKHFEFLQELDKIINEKR-DWR-QNDRQTILQMIIKLSDISTIFRKFELAD 1068
Query: 576 KWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRD 668
+W+ +CEEFFRQGD EK + T L DR+
Sbjct: 1069 RWTAVLCEEFFRQGDLEKAAGMEYTSPLNDRE 1100
>UniRef50_UPI0000D577EC Cluster: PREDICTED: similar to CG32648-PA;
n=2; Coelomata|Rep: PREDICTED: similar to CG32648-PA -
Tribolium castaneum
Length = 938
Score = 101 bits (242), Expect = 2e-20
Identities = 63/210 (30%), Positives = 102/210 (48%), Gaps = 3/210 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
P+HN H V Q M+ + + + +E++ L S I HD+ HPG N + I
Sbjct: 245 PFHNFRHCFCVAQMMYAISWSVDLPSKVGDLEVLILLTSCICHDLDHPGYNNIYQINAKT 304
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVLI---MA 413
LA Y + S LE+HH A + + E+ K + +I +A
Sbjct: 305 ELAIRYN-------DISPLENHHCSVAFRILENEDCNIFKSFKSEDFKTVREGIIRCILA 357
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ R ++ L+ F+++ T D + H L+ + +K +DISN RP V++ W ++
Sbjct: 358 TDMARHNEILTNFREI--TPNFDYNDKAHVNLLCMVLIKVSDISNEARPMDVAEPWLDRL 415
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+EFF+Q D EK+ LPVT DR+ + P
Sbjct: 416 LQEFFKQSDAEKLEGLPVTPFMDREKITKP 445
>UniRef50_A2F408 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1086
Score = 101 bits (242), Expect = 2e-20
Identities = 67/211 (31%), Positives = 103/211 (48%), Gaps = 4/211 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA DVTQ + ++ + +E+ A +++A+ HD H G F
Sbjct: 807 PYHNWRHACDVTQFVTYEIILSGAEKILSNMELFALIVAALCHDANHDGFTNVFNEKAET 866
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEERPDLQEELKKHLKV-LIMA 413
L L++ N SV+E+HH A+ I E+ L + + + LI+A
Sbjct: 867 PLGILFK-------NQSVMETHHCEVAIGIISKEETNLFAKLKSQDFKFMWTTIIELILA 919
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+++ L FK L D D + R+ ++++ LK ADISN RP+ ++ +W +
Sbjct: 920 TDMSKHFTLLKEFKALNDEGKWDKTQPDIRLRMMKLLLKTADISNVSRPFELADRWCDVL 979
Query: 594 CEEFFRQGDYEKMLDLPVT-QLCDRDSTSIP 683
CEEFFRQGD E + T L DR+ P
Sbjct: 980 CEEFFRQGDLEMASGMQYTSDLNDREHLDKP 1010
>UniRef50_Q16VA1 Cluster: High-affinity cgmp-specific 3,5-cyclic
phosphodiesterase; n=1; Aedes aegypti|Rep: High-affinity
cgmp-specific 3,5-cyclic phosphodiesterase - Aedes
aegypti (Yellowfever mosquito)
Length = 1022
Score = 100 bits (240), Expect = 4e-20
Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 3/215 (1%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
+++ P+HN H V Q M+ ++ + +E++ L+S I HD+ HPG N +
Sbjct: 98 HYNDVPFHNYRHCFCVAQMMYAITWHTNLVQRLGELEVLILLVSCICHDLDHPGYNNIYQ 157
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEER---PDLQEELKKHLK 398
I LA Y + S LE+HH A + R DL +++++ +
Sbjct: 158 INARTELALRYN-------DISPLENHHCSIAFRLLEHPDCNIFRNMSKDLYKDVREGII 210
Query: 399 VLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
I+ATD+ R ++ L++F++ T D + H L+ + +K ADISN RP V++
Sbjct: 211 RCILATDMARHNEILTQFQEA--TPVFDYNNKVHTNLLCMVLIKVADISNEARPMDVAEP 268
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
W ++ +EFF Q EK LPVT D D S P
Sbjct: 269 WLDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKP 303
>UniRef50_A4HHP3 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania braziliensis
Length = 734
Score = 100 bits (240), Expect = 4e-20
Identities = 64/214 (29%), Positives = 106/214 (49%), Gaps = 5/214 (2%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQG--SIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+S YH NPYHN++H DVTQ + ++ S++ + EI A +++ HD HPG+
Sbjct: 453 QSAYHP-NPYHNAMHGADVTQINYYIMIVAGLSVKCCLSNEEIFAGIIAGAVHDFDHPGL 511
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQEEL- 383
N F T +LA LY + S+LE+HH + + D Q L
Sbjct: 512 NNNFHSRTGAYLATLY-------NDRSILENHHLACTFELLRNPRYNIFATLSDEQRLLV 564
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
++ + +++ATD+ F+ + T +E L L +++K ADISN RP
Sbjct: 565 RETILEMVLATDMGNHARIFKNFQVRMSEATEWHSKKEDVRLALSMSIKMADISNCARPN 624
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDR 665
+ +W+ + +EF+ QGD E+ L+L ++ DR
Sbjct: 625 HIYAEWAKNISKEFYLQGDAERKLNLSISPFMDR 658
>UniRef50_A2FKH2 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1086
Score = 100 bits (240), Expect = 4e-20
Identities = 64/206 (31%), Positives = 101/206 (49%), Gaps = 5/206 (2%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA DVTQ + L+ + E+ L++ + HD H G + +
Sbjct: 810 PYHNWRHAVDVTQFVTYELITSGYDKILSSFELYGLLVACLCHDANHDGFTNVYNVKAET 869
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEE-RPDLQEELKKHLKVLIMA 413
L L++ N SV+E+HH A+ I E+ + P +++ + LI+
Sbjct: 870 PLGILFK-------NQSVMETHHCAIAIDIISKEETNIFASLNPAEYKKMWSLIINLILI 922
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQ-EHRILVLQIALKCADISNPCRPWSVSQKWSVK 590
TD+ + +L F L D + +H ++++Q+ LKC DISN RP+ ++ KW
Sbjct: 923 TDMAKHFTFLKEFNGLFDAGEWKPKENPQHFLMLMQMLLKCGDISNVSRPFELADKWCDV 982
Query: 591 VCEEFFRQGDYEKMLDLPVT-QLCDR 665
+CEEFFRQGD E+ + T L DR
Sbjct: 983 LCEEFFRQGDLEQAQGMNYTSDLNDR 1008
>UniRef50_Q5CXM2 Cluster: Membrane associated HD superfamily cyclic
nucleotide phosphodiesterase domain containing protein;
n=2; Cryptosporidium|Rep: Membrane associated HD
superfamily cyclic nucleotide phosphodiesterase domain
containing protein - Cryptosporidium parvum Iowa II
Length = 1967
Score = 73.3 bits (172), Expect(2) = 5e-20
Identities = 47/154 (30%), Positives = 76/154 (49%), Gaps = 4/154 (2%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
LF L Y+S PYHN HA V Q + L I + + L +A+ HDI H
Sbjct: 1537 LFDLIHDSYNSDIPYHNIFHALQVVQVCYIILRNFGIMLVLNDLNKFILLFAALCHDIDH 1596
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEEL 383
PGVN FL + + LA Y ++N S+LE+HH S + + L+ R + +
Sbjct: 1597 PGVNNCFLTISNSKLALKY------NDN-SILENHHCNYIFSLLDKCQDLDIRKNFNDFE 1649
Query: 384 KKHLKVL----IMATDITRQHDYLSRFKKLLDTN 473
KK+ + + +++TD++ + LS ++ + TN
Sbjct: 1650 KKNFRRIFIRSVLSTDMSYHNTLLSNLEEFISTN 1683
Score = 47.6 bits (108), Expect(2) = 5e-20
Identities = 23/67 (34%), Positives = 36/67 (53%)
Frame = +3
Query: 462 LDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDL 641
+D N+L +++ + +++ L ADISNP P+ + KWS + EEF Q E L
Sbjct: 1723 IDENSLLIKMDKE--FLIETLLHAADISNPITPFPICAKWSSLIVEEFNYQSKLESQFGL 1780
Query: 642 PVTQLCD 662
P+T D
Sbjct: 1781 PITPFMD 1787
>UniRef50_Q9VYJ0 Cluster: CG32648-PA; n=3; Coelomata|Rep: CG32648-PA
- Drosophila melanogaster (Fruit fly)
Length = 963
Score = 100 bits (239), Expect = 5e-20
Identities = 66/215 (30%), Positives = 105/215 (48%), Gaps = 3/215 (1%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
+++ P+HN H V Q M+ Q ++ + + +E + L+S I HD+ HPG N +
Sbjct: 104 HYNEVPFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQ 163
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEE-RPDLQEELKKHLK 398
I LA Y + S LE+HH A + E + + D +++ +
Sbjct: 164 INARTELALRYN-------DISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGII 216
Query: 399 VLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
I+ATD+ R ++ L++F ++ T D + H L+ I +K ADISN RP V++
Sbjct: 217 RCILATDMARHNEILTQFMEI--TPIFDYSNRAHINLLCMILIKVADISNEARPMDVAEP 274
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
W ++ +EFF Q EK LPVT D D S P
Sbjct: 275 WLDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKP 309
>UniRef50_A5JZK2 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=5; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 1164
Score = 100 bits (239), Expect = 5e-20
Identities = 70/270 (25%), Positives = 124/270 (45%), Gaps = 5/270 (1%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F F ++ PYHN+IHAT VTQ C + I + + +S I HD+ HP
Sbjct: 858 FLSFVEKQYNNVPYHNTIHATMVTQKFFCLSKKLGIYDHMEYKIKLVMFISGICHDVGHP 917
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEERPDLQEE 380
G N F + + + L+ +Y + SVLE++H + + LL+ +
Sbjct: 918 GYNNLFFVNSLHPLSIIYN-------DISVLENYHASITFKILQLNQCNLLKSFSEKDFR 970
Query: 381 L-KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLD-MRIQEHRILVLQIALKCADISNPC 554
L + ++ LI++TD+ + +S+F+ + D ++ + ++++++ +K ADIS+
Sbjct: 971 LIRSYIIELILSTDMKYHFEIISKFRIRRENEDFDYVKNNDDLLVLIKMIIKSADISHGS 1030
Query: 555 RPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXIT 734
W+ KW +V EF+ QGD E +P++ LCDR + + + +P
Sbjct: 1031 VKWNEHYKWCQRVLCEFYSQGDEELKNKMPLSPLCDRTKHNEVCQSQITFLKFVVMPLFE 1090
Query: 735 EWNRFLDSKLSXEMXANXXY-NEVQWELLM 821
E D K + N + WE LM
Sbjct: 1091 ELTYIDDIKFVKNFCLKRLHSNCLMWEKLM 1120
>UniRef50_UPI0000D555D7 Cluster: PREDICTED: similar to
phosphodiesterase 10A; n=4; Tribolium castaneum|Rep:
PREDICTED: similar to phosphodiesterase 10A - Tribolium
castaneum
Length = 745
Score = 99 bits (238), Expect = 7e-20
Identities = 65/211 (30%), Positives = 110/211 (52%), Gaps = 1/211 (0%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
++ NPYHN HA +V M+ +L+ +I+ F EI A +++A+ HD+ HPG FL
Sbjct: 499 FYRRNPYHNFEHAFNVVHCMY-LILKRNIKQFTE-TEIKALMIAALCHDVDHPGFTNNFL 556
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEE-RPDLQEELKKHLKVL 404
+ N LA+LY EN S LE+H + A+ + + +L + E L+ +K
Sbjct: 557 ELSNNDLANLY-------EN-SCLENHQYYVAMLLLDHNKVLTHLSKEEYEVLRTEIKQA 608
Query: 405 IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWS 584
I+ATD +K+ +T++ D + HR + + AD+S C+P+ VS++ +
Sbjct: 609 IIATDPLVYFANQINLEKICNTHSFDWGNETHRYYLKGTMMMVADLSGMCKPFLVSKRIT 668
Query: 585 VKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ E + QGD EK + L + DRD ++
Sbjct: 669 DNLYAECYLQGDLEKEMGLCPLSMMDRDKSN 699
>UniRef50_A7AS42 Cluster: 3'5'-cyclic nucleotide phosphodiesterase,
putative; n=1; Babesia bovis|Rep: 3'5'-cyclic nucleotide
phosphodiesterase, putative - Babesia bovis
Length = 485
Score = 99 bits (238), Expect = 7e-20
Identities = 72/217 (33%), Positives = 113/217 (52%), Gaps = 9/217 (4%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQG-SIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIAT 236
NPYHN++H V M C LL+ S+ ++ P+E A L++A+ HD HPG FL +T
Sbjct: 208 NPYHNALHGACVAH-MSCVLLKALSLEQYLTPLEQFAYLIAALGHDAGHPGKTNAFLRST 266
Query: 237 CNHLADLYRILEGTSENFSVLESHHWRAALSC-IIES-----GLLEERPDLQEELKKHLK 398
N LA +Y + S+LE++H A+L C II + GL ++ E ++K +
Sbjct: 267 QNPLALIY-------NDASILENYH--ASLVCHIIRAKEDFFGLFNQQD--WEIIRKRII 315
Query: 399 VLIMATDITRQHDYLSRFKKLLDTNTLD-MRIQEHRILVLQIALKCADISNPCRPWSVSQ 575
L++ATD+ +++ K+ + T D + E L + +K ADI + PW
Sbjct: 316 QLVLATDMMTHFTHVNNVKERRLSGTFDYVNNPEDLWFCLVLLVKTADIGHNFLPWCEHL 375
Query: 576 KWSVKVCEEFFRQGDYEKMLDLPVTQLCDRD-STSIP 683
W+ + +EF QGD E++L LP+ DR S IP
Sbjct: 376 PWTNALFDEFHMQGDEERLLSLPLLLFFDRTRSADIP 412
>UniRef50_A2DM90 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 457
Score = 99.5 bits (237), Expect = 9e-20
Identities = 73/223 (32%), Positives = 111/223 (49%), Gaps = 6/223 (2%)
Frame = +3
Query: 33 LFESGYHSTN-PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPG 209
+ E+ H N PYHN HATD TQ + + + + P++ A LLS I HD+ H G
Sbjct: 199 IVEAQSHYNNVPYHNWRHATDATQFVFYLITMPHVEEMLPPLDRFALLLSVICHDLEHNG 258
Query: 210 VNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL---LEERPDLQEE 380
+ H + + LE+HH + A +I+ L LE D Q+E
Sbjct: 259 HTNDY------HRKVNSEFSQEAGPDLPPLENHHQKLA-KVLIQKHLKYTLEHLTDEQKE 311
Query: 381 -LKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
+ + + +I +TD+ + YL + + + D I E RIL Q +K AD+SN CR
Sbjct: 312 NMFRFITEIIFSTDMGKHKFYLEKI--VANIGKFDGSI-ELRILTCQAIMKLADLSNTCR 368
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRD-STSIP 683
P+ S K + ++ +E+F QGD EK L LP++ DRD T +P
Sbjct: 369 PFDDSCKMAKRLNDEWFIQGDDEKKLGLPISNGMDRDHPTPLP 411
>UniRef50_Q7PQX7 Cluster: ENSANGP00000010843; n=6; Coelomata|Rep:
ENSANGP00000010843 - Anopheles gambiae str. PEST
Length = 547
Score = 98.7 bits (235), Expect = 2e-19
Identities = 63/215 (29%), Positives = 106/215 (49%), Gaps = 3/215 (1%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
+++ P+HN H V Q M+ ++ + +E++ L+S I HD+ HPG N +
Sbjct: 93 HYNDVPFHNYRHCFCVAQMMYTIAWHTNLVQRLGELEVLVLLVSCICHDLDHPGYNNIYQ 152
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEERP-DLQEELKKHLK 398
I LA Y + S LE+HH A + E + ++ +++++ +
Sbjct: 153 INARTELALRYN-------DISPLENHHCSIAFRLLEHPECNIFRNMSKEMYKDVREGII 205
Query: 399 VLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
I+ATD+ R ++ L++F++ T D + H L+ + +K ADISN RP V++
Sbjct: 206 RCILATDMARHNEILTQFQEA--TPEFDYSNKVHTNLLCMVLIKVADISNEARPMDVAEP 263
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
W ++ +EFF Q EK LPVT D D S P
Sbjct: 264 WVDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKP 298
>UniRef50_A1D4A4 Cluster: High affinity cAMP phosphodiesterase,
putative; n=8; Trichocomaceae|Rep: High affinity cAMP
phosphodiesterase, putative - Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 1009
Score = 98.3 bits (234), Expect = 2e-19
Identities = 76/222 (34%), Positives = 112/222 (50%), Gaps = 26/222 (11%)
Frame = +3
Query: 42 SGYHSTNPYHNSIHATDVTQAMHCFLLQ-----------------GSIRAFIRPVEIIAC 170
+ Y+S YHN HA DV Q++ CFL+ SI + + P + +
Sbjct: 355 ASYNSFVLYHNFRHAIDVLQSVFCFLVHIGALPPYGSVGTSPDSPSSIASLLTPFDTLTL 414
Query: 171 LLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL 350
L+SAI HD+ HPGVN FL+ LA LY ++N SVLE+ H AA S I+
Sbjct: 415 LISAIGHDVGHPGVNNFFLVKLNAPLAQLY------NDN-SVLEAFHC-AAFSQILRRHW 466
Query: 351 LEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDT-----NTLD----MRIQEHR 503
D Q L+K L I+ATD+ ++ R L + ++D I+ ++
Sbjct: 467 PAAFKDRQ--LRKLLISSILATDMGVHQKFMERLGSLQEKFYANGKSVDGWKPQDIEIYK 524
Query: 504 ILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEK 629
LV + +KCADISN RPW +++KW+ + EEF QG+ E+
Sbjct: 525 TLVCGLLIKCADISNVARPWDIAEKWTKILQEEFANQGEMER 566
>UniRef50_A2G2M9 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1136
Score = 97.9 bits (233), Expect = 3e-19
Identities = 61/211 (28%), Positives = 109/211 (51%), Gaps = 4/211 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN IHA DV Q + + + + E++A ++A+ HD H G+N F +
Sbjct: 855 PYHNWIHAIDVLQYISYQVRITNSHKILTQFELLAVCVAALCHDAGHQGLNNAFNVNAET 914
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEERPDLQ-EELKKHLKVLIMA 413
L L++ + SV+E+ H A+ + E+ L + + K + LI+A
Sbjct: 915 PLGILFK-------DQSVMETFHCTVAIRILSQPETNLFHSLNTKELTVIWKWIIHLILA 967
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + + + L+ ++++ + HR++ +++ +K +DISN RP+ + KW +
Sbjct: 968 TDMAFHFKLIKQGNEALEAGVINLKEEAHRLMCMELVMKVSDISNVSRPFKYADKWCEVL 1027
Query: 594 CEEFFRQGDYEKMLDLPVT-QLCDRDSTSIP 683
EEF+RQGD EK L LP + L +R+ + P
Sbjct: 1028 SEEFWRQGDKEKELGLPYSGPLMNREGQNKP 1058
>UniRef50_O00408 Cluster: cGMP-dependent 3',5'-cyclic
phosphodiesterase; n=47; Eumetazoa|Rep: cGMP-dependent
3',5'-cyclic phosphodiesterase - Homo sapiens (Human)
Length = 941
Score = 97.9 bits (233), Expect = 3e-19
Identities = 65/223 (29%), Positives = 111/223 (49%), Gaps = 6/223 (2%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRA--FIRPVEIIACLLSAIAHDIFHP 206
+ + GY PYHN +HA V+ C+LL ++ ++ +EI A +S + HD+ H
Sbjct: 645 MVKKGYRDP-PYHNWMHAFSVSH--FCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHR 701
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLE--ERPDLQ 374
G N F +A+ + LA LY S SV+E HH+ A++ + G + + R D Q
Sbjct: 702 GTNNSFQVASKSVLAALY------SSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQ 755
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPC 554
L ++ +I+ATD+ +K+ + Q HR+L+ + C D+S+
Sbjct: 756 RMLDL-MRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSC-DLSDQT 813
Query: 555 RPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+ W ++K + + +EFF QGD EK + ++ DR+ IP
Sbjct: 814 KGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIP 856
>UniRef50_UPI0000E48F4D Cluster: PREDICTED: similar to camp and
camp-inhibited cgmp 3,5-cyclic phosphodiesterase; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
camp and camp-inhibited cgmp 3,5-cyclic
phosphodiesterase - Strongylocentrotus purpuratus
Length = 1197
Score = 97.5 bits (232), Expect = 4e-19
Identities = 58/213 (27%), Positives = 105/213 (49%), Gaps = 4/213 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V +++ ++ G + F P+E +A ++ + HD+ H G N F++ T +
Sbjct: 32 PYHNWTHAFSVAHSVYTMIMTGQGQVF-NPLEALALFVACLCHDLDHRGKNNAFMVNTAS 90
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHL---KVLIMA 413
LA +Y + S +E HH+ ++ + G + EE K+ L + I+A
Sbjct: 91 PLASVY--------STSTMEHHHFNMTITILQNDGHNIFKHLSSEEYKQVLGDIRHAILA 142
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ ++ KK+++ QEHR V +++ D++ +PW + Q+ +
Sbjct: 143 TDLALFFPNKAKLKKIVEEKNFSWDNQEHRQCVKALSMTACDLAANTKPWHIQQQTVKVI 202
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD-STSIPXN 689
+EF++QGD EK + DRD + +P N
Sbjct: 203 FDEFYQQGDEEKAAGRNPIPMMDRDRAHELPAN 235
>UniRef50_Q4N806 Cluster: 3',5' cyclic nucleotide phosphodiesterase,
putative; n=2; Theileria|Rep: 3',5' cyclic nucleotide
phosphodiesterase, putative - Theileria parva
Length = 450
Score = 97.1 bits (231), Expect = 5e-19
Identities = 76/273 (27%), Positives = 132/273 (48%), Gaps = 11/273 (4%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
++ NPYHN++HA V + + + P E A ++S++AHD+ HPG +L
Sbjct: 163 HYLANPYHNALHAATVGHMSKLLSNIVTTKRRLNPYEEFAFIISSLAHDVGHPGKTNNYL 222
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERP-DLQEELKKHLK 398
T N L+ +Y ++N S LE++H + L II++ P D+ L+K +
Sbjct: 223 SNTSNVLSLIY------NDN-STLENYHC-SLLFYIIKNNTNFYSIIPKDIWPSLRKRII 274
Query: 399 VLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
LI++TD+ ++ K+ D++ + L+L + +K ADI + PW+
Sbjct: 275 QLILSTDMINHFLHIDNVKEKRLQGKFDIKNDDDFWLLLVLCIKAADIGHNFLPWADHLP 334
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQLCDR-DSTSIP------XNTNXLL*IYXSLPXITE 737
W+ + EEF++QGD EKM + DR +S +IP NT L + S P ++E
Sbjct: 335 WTQVLFEEFYKQGDEEKMQSISPLMFFDRNESRNIPILQLQFFNTMTQL-LILSQPLLSE 393
Query: 738 WNRFLDSKLSXEMXA-NXXYNEVQWELLMTKXV 833
N F ++ ++ + N N W+ K +
Sbjct: 394 LNYFDENNFINDILSKNSNDNANNWKKYENKSI 426
>UniRef50_Q9HCR9 Cluster: Dual 3',5'-cyclic-AMP and -GMP
phosphodiesterase 11A; n=42; Eumetazoa|Rep: Dual
3',5'-cyclic-AMP and -GMP phosphodiesterase 11A - Homo
sapiens (Human)
Length = 934
Score = 97.1 bits (231), Expect = 5e-19
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 663 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 722
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 723 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 775
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 776 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 835
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 836 SEFFEQGDRERLELKLTPSAIFDRN 860
>UniRef50_UPI00006CF33D Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 354
Score = 96.7 bits (230), Expect = 7e-19
Identities = 61/200 (30%), Positives = 105/200 (52%), Gaps = 3/200 (1%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
NP+HN H V ++ + QG + +E + L SA+ HD+ H G + + +
Sbjct: 93 NPFHNFDHGITVAHGIYYIIKQGITNKHLNQLEKFSLLFSALCHDVDHTGHSNAYETNSK 152
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQEELKKHLKVLIMAT 416
+ L LY N S LE HH+ + + GL + P D +KK+++ I+AT
Sbjct: 153 SELFTLYG-------NESPLEKHHYAQTIQIADQCGLFDSIPQDQLVIMKKYIQHNILAT 205
Query: 417 DITRQHDYLSRFKKLLDTNTL-DMRIQEHRILVLQIAL-KCADISNPCRPWSVSQKWSVK 590
D+++ + ++ FK+ L + D+ I E + + L AL ADI P R +S+S++WS++
Sbjct: 206 DMSKHNQIMNEFKENLPSLLKEDLAITEQQKINLCGALVHAADIGAPTRDFSISKEWSLR 265
Query: 591 VCEEFFRQGDYEKMLDLPVT 650
+ +EF Q + E+ +LPVT
Sbjct: 266 IAKEFTAQLELEQQNNLPVT 285
>UniRef50_A7AR41 Cluster: 3'5'-cyclic nucleotide phosphodiesterase,
putative; n=1; Babesia bovis|Rep: 3'5'-cyclic nucleotide
phosphodiesterase, putative - Babesia bovis
Length = 777
Score = 96.3 bits (229), Expect = 9e-19
Identities = 62/212 (29%), Positives = 107/212 (50%), Gaps = 3/212 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E+ Y + PYHN +H V Q + C + + ++ +++A++HD+ HPG N
Sbjct: 489 ENQYRNV-PYHNKMHGAMVAQKVLCLASYTGLLEHLSILDEALLMVAALSHDVGHPGRNN 547
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-LKKHL 395
F + T + +A LY + SVLE++H +AL + G PD + ++ +
Sbjct: 548 AFFVRTHHPVAQLYN-------DTSVLENYHAASALRVLCTPGC-NLFPDCDYDYVRSQI 599
Query: 396 KVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEH--RILVLQIALKCADISNPCRPWSV 569
I+ATD Q +S+F +L D +E+ RIL ++ +K AD++ P W+
Sbjct: 600 IEHILATDTVDQFHMISQF--VLSCKRDDFTFEEYNSRILTSKMLMKAADVAAPTMQWAN 657
Query: 570 SQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDR 665
S +W ++ EF+ QG E +P++ LCDR
Sbjct: 658 SLEWVSRLLGEFYAQGAEEVDYCIPISALCDR 689
>UniRef50_A2EHB3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=2; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1213
Score = 96.3 bits (229), Expect = 9e-19
Identities = 62/197 (31%), Positives = 101/197 (51%), Gaps = 4/197 (2%)
Frame = +3
Query: 63 PYHNSIHATDVTQAM-HCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
PYHN HA D Q M H +L G ++ + EI+ L++ I HD H G + +
Sbjct: 915 PYHNFTHAIDTMQFMAHVIILCG-LKDVLTQKEILILLVACICHDANHDGFSNNYNYKAQ 973
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEERPDLQEELKKHLKV-LIM 410
L+ L++ SVLE+HH +++ + ES L PD + L + L+M
Sbjct: 974 TPLSILFK-------GQSVLETHHCSVSITILSKDESALFNNFPDDEIASVWTLFIDLVM 1026
Query: 411 ATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVK 590
ATD+++ D + ++ L + R+L +++ +K ADISN R + + +W+
Sbjct: 1027 ATDMSKHFDIVDEMREYLAMGLTWKDHPKGRLLFMKLLIKAADISNCVREFETADRWADV 1086
Query: 591 VCEEFFRQGDYEKMLDL 641
+CEEFFRQGD E+ L +
Sbjct: 1087 LCEEFFRQGDLERALGM 1103
>UniRef50_O43851 Cluster: PDE4C-delta109; n=18; Bilateria|Rep:
PDE4C-delta109 - Homo sapiens (Human)
Length = 427
Score = 96.3 bits (229), Expect = 9e-19
Identities = 58/191 (30%), Positives = 108/191 (56%), Gaps = 9/191 (4%)
Frame = +3
Query: 135 RAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHW 314
+A +EI+A L ++ HD+ HPGV+ FLI T + LA +Y + SVLE+HH
Sbjct: 125 QAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYN-------DASVLENHHL 177
Query: 315 RAALSCI-IESGLLEERPDLQEELKKHLKVL--IMATDITRQHDYLSRFKKLLDTN---T 476
+ E+ + + ++ L V+ ++ATD+++ + L+ K +++T +
Sbjct: 178 AVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 237
Query: 477 LDMRIQEH---RILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPV 647
L + + ++ RI VLQ + CAD+SNP +P + ++W+ ++ EFF+QGD E+ L +
Sbjct: 238 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 297
Query: 648 TQLCDRDSTSI 680
+ +CD+ + S+
Sbjct: 298 SPMCDKHTASV 308
>UniRef50_Q54HY3 Cluster: Putative uncharacterized protein Pde4;
n=2; Dictyostelium discoideum|Rep: Putative
uncharacterized protein Pde4 - Dictyostelium discoideum
AX4
Length = 771
Score = 95.9 bits (228), Expect = 1e-18
Identities = 54/147 (36%), Positives = 90/147 (61%), Gaps = 3/147 (2%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
ESGY STNPYHNSIHATDV ++ F ++ S F+ +E+ + +L+AI HD HPGVN
Sbjct: 331 ESGYDSTNPYHNSIHATDVLHNLNYF-IEKSFGKFLTDIELFSMILAAIIHDFKHPGVNN 389
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI--IESGLLEERPD-LQEELKK 389
F I + + LA Y + S+LE++H A + ESG+L + D +++E+++
Sbjct: 390 HFQINSKSRLALKY-------NDKSILENYHLHQAFIIMNEPESGILLKLSDSVRKEIRE 442
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT 470
+ L+++TD+ + + + RFK + ++
Sbjct: 443 TIIALVLSTDMAKHFNLVGRFKSMANS 469
Score = 67.3 bits (157), Expect = 5e-10
Identities = 26/59 (44%), Positives = 44/59 (74%)
Frame = +3
Query: 492 QEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRD 668
++ R+L+++I++KCADISNP +PW++ WS +V EF++QGD EK ++ V+ DR+
Sbjct: 578 KKDRLLLMKISIKCADISNPSKPWNLYTNWSNRVTSEFYKQGDKEKESNMDVSAFMDRN 636
>UniRef50_A2GFY4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 457
Score = 95.1 bits (226), Expect = 2e-18
Identities = 61/211 (28%), Positives = 104/211 (49%), Gaps = 4/211 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA D Q ++ LLQ I FI+P++ + + +AI HD+ H G + F
Sbjct: 210 PYHNWRHACDACQFVYFALLQKPIEHFIQPIDYFSLMTAAICHDVGHNGRSNDF------ 263
Query: 243 HLADLYRILEGTSENFSVLESHHWRAA---LSCIIESGLLEERPDLQEELKKHLKVLIMA 413
H + + + N LE HH + LS + + + K + +I+A
Sbjct: 264 HRQVNSKYAQESGSNQPPLEYHHQKITIEFLSNEFSKSIQTFNDETRRIYFKFVSNIILA 323
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+++ DY+ F + + ++ R+L Q +K AD+SN CRP+ + S ++
Sbjct: 324 TDMSKHQDYIVSFNNIAGSY---KDTEDERLLACQAIMKLADLSNTCRPFGEAATMSAQL 380
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRDS-TSIP 683
EE++ QGD + L +T+ DR++ T +P
Sbjct: 381 QEEWYTQGDEQLKRGLEITKGFDRNNKTPLP 411
>UniRef50_O96076 Cluster: EFPDE2; n=1; Ephydatia fluviatilis|Rep:
EFPDE2 - Ephydatia fluviatilis
Length = 819
Score = 94.7 bits (225), Expect = 3e-18
Identities = 65/221 (29%), Positives = 102/221 (46%), Gaps = 4/221 (1%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ + GY PYHN +HA V ++ S + + +E++A +S + HDI H G
Sbjct: 553 MVKKGYRDP-PYHNWMHAFSVAHFLYALYCCSSKLSCLDDLEVLALFVSCLCHDIDHRGT 611
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES---GLLEERPDLQEEL 383
N F + + + LA LY S SV+E HH L CI+ S + E D
Sbjct: 612 NNAFQVCSNSTLACLY------SSEGSVMERHHLAQTL-CILNSPGCNIFENLSDSDYRT 664
Query: 384 KKHL-KVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRP 560
L + I+ TDI L K++ + + HR++ I C D++ C+
Sbjct: 665 TIQLIQDNILDTDIASHLKKLKHIKQMANDGYERSNPEHHRLMCSLIMTSC-DLTASCKT 723
Query: 561 WSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
W ++ S + +EFF QGD EK L + +++ DRD IP
Sbjct: 724 WESNKAISDLIYQEFFSQGDLEKALGVTPSEMMDRDRAFIP 764
>UniRef50_Q1JT10 Cluster: Phosphodiesterase, putative; n=2;
Eukaryota|Rep: Phosphodiesterase, putative - Toxoplasma
gondii RH
Length = 2092
Score = 94.3 bits (224), Expect = 3e-18
Identities = 71/239 (29%), Positives = 110/239 (46%), Gaps = 27/239 (11%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + GYH+ NPYHN HA V Q FL R + P+E + LL+A+ HD+ HP
Sbjct: 1744 FAIIRDGYHTDNPYHNFYHAIHVFQVCWMFLSAYGCRNILSPIEQLGILLAALCHDVDHP 1803
Query: 207 GVNQGFLIATCNHLADLYR---ILEGTSENFSV--LESHHWRAALSCIIESG---LLEER 362
GVN FL A+ + L+ +Y +LE F++ + A S I SG
Sbjct: 1804 GVNNAFLRASLHPLSIMYNDKSVLENHHAAFAIRTMMQLGMYGAGSRIFPSGSGAAAPAS 1863
Query: 363 PDLQE----------------ELKKHLKVLIMATDIT---RQHDYLSRFKKLLDTNTLDM 485
PD + EL+K + I +TD+ + HD + R ++ + ++
Sbjct: 1864 PDGKSGSSGSRFEGRIVPSFSELRKIVIQAIFSTDMELFRQHHDAMKRRAQMKTNDREEL 1923
Query: 486 RIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCD 662
++ R L++ + CADI NP + +W+ V +EF Q D E+ LPV+ D
Sbjct: 1924 EGEDDRNLLVTCLIHCADICNPVMSEGRNVQWASLVTQEFNAQVDLERRYGLPVSVFMD 1982
>UniRef50_O76074 Cluster: cGMP-specific 3',5'-cyclic
phosphodiesterase; n=47; Euteleostomi|Rep: cGMP-specific
3',5'-cyclic phosphodiesterase - Homo sapiens (Human)
Length = 875
Score = 93.9 bits (223), Expect = 5e-18
Identities = 64/214 (29%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ Y YHN HA + Q M L G I+ + +EI+A L++A++HD+ H GVN
Sbjct: 603 KKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNN 662
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK 398
++ + + LA LY S++E HH+ L + G EE K LK
Sbjct: 663 SYIQRSEHPLAQLY--------CHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLK 714
Query: 399 VL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I+ATD+ F +L+ N ++ + L L + + D+S +PW +
Sbjct: 715 IIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPI 774
Query: 570 SQKWSVKVCEEFFRQGDYE-KMLDLPVTQLCDRD 668
Q+ + V EFF QGD E K L++ T L +R+
Sbjct: 775 QQRIAELVATEFFDQGDRERKELNIEPTDLMNRE 808
>UniRef50_Q16HU8 Cluster: Camp and camp-inhibited cgmp 3,5-cyclic
phosphodiesterase; n=5; Eumetazoa|Rep: Camp and
camp-inhibited cgmp 3,5-cyclic phosphodiesterase - Aedes
aegypti (Yellowfever mosquito)
Length = 767
Score = 93.5 bits (222), Expect = 6e-18
Identities = 60/217 (27%), Positives = 102/217 (47%), Gaps = 3/217 (1%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
FTL + PYHN H V M+ +++ F RP E +A + ++ HD+ H
Sbjct: 501 FTLTVKKNYRRVPYHNWTHGFSVANTMYS-IIKNCPHVF-RPNECLALFIGSLCHDLDHR 558
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQE 377
G N F++ T + LA +Y + S +E HH+ ++ + + G + + +
Sbjct: 559 GKNNKFMLDTESPLAAIY--------STSTMEHHHFNQTVTILQQEGHNIFSKLNSNEYK 610
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++ +K I+ATD+ + KL+D + EHR+L+ IA+ AD+S +
Sbjct: 611 QVLSLIKHCILATDLALFFPNKDKLSKLVDNEQFSWTVAEHRMLIQTIAMTGADLSASAK 670
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRD 668
PW+V + + EF+ QGD EK + DRD
Sbjct: 671 PWAVQTETVKVIFAEFYDQGDEEKKAGRQPIAMMDRD 707
>UniRef50_Q9VFI9 Cluster: CG8279-PA; n=8; Endopterygota|Rep: CG8279-PA
- Drosophila melanogaster (Fruit fly)
Length = 1131
Score = 93.1 bits (221), Expect = 8e-18
Identities = 58/205 (28%), Positives = 97/205 (47%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L G + F+ +EI+ L++ + HD+ H G N F T +
Sbjct: 730 YHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESP 789
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY S +E HH+ + + G P+ + K ++ I++T
Sbjct: 790 LAILY--------TTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILST 841
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+ + F +L++ D + +E + L+ + + D+S +PW V K + V
Sbjct: 842 DLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVA 901
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
+EFF QGD EK+ L+ + DR+
Sbjct: 902 DEFFDQGDLEKLQLNTQPVAMMDRE 926
>UniRef50_O96077 Cluster: EFPDE3; n=1; Ephydatia fluviatilis|Rep:
EFPDE3 - Ephydatia fluviatilis
Length = 1054
Score = 93.1 bits (221), Expect = 8e-18
Identities = 68/238 (28%), Positives = 114/238 (47%), Gaps = 32/238 (13%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQ-------------------------GSIRAFIRP 152
++ N YHN +HA DV A L + G++ +
Sbjct: 606 HYGNNVYHNKVHAADVLHATSYLLFEIIPEFSCTVSSSERVWTGNQRTRMGGNVASAFSI 665
Query: 153 VEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAA--- 323
+E+ A ++A HD HPG FL+AT + LA LY + +VLE+HH A+
Sbjct: 666 LEVFATYMAAAVHDFDHPGRTNAFLVATKSPLAILY-------NDRAVLENHHCAASWDL 718
Query: 324 LSCIIESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFKKLLDTNT---LDMRI 491
L+ + E L + + + + + L V ++ATD+ D LS F+ +D +D
Sbjct: 719 LTSVPEHNFLGDMEEAELKRFRFLLVEAVLATDLKMHFDLLSDFRAKVDPEEDGGIDWSS 778
Query: 492 QEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDR 665
+ R+ V+++ +K ADIS P + + + + W+ + EEF++QG+ E +L LP T DR
Sbjct: 779 EVDRLTVMKMIMKMADISTPTKSYELHRAWTKLITEEFYQQGEQEIVLGLPPTIFLDR 836
>UniRef50_Q8I0P7 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-3; n=4; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-3 - Caenorhabditis elegans
Length = 578
Score = 93.1 bits (221), Expect = 8e-18
Identities = 68/246 (27%), Positives = 118/246 (47%), Gaps = 28/246 (11%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMH---------CFLL----------------QGS 131
F E GY PYHN IHA DV + FL S
Sbjct: 243 FHALEKGYWEI-PYHNRIHAADVLHGCYYLSAHPVRSTFLTPKTPDSVLTPPHPHHQHSS 301
Query: 132 IRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHH 311
I + + +E++A +A HD HPG FL+ + A LY + SVLE+HH
Sbjct: 302 IMSQLSTLELMALFTAAAMHDYDHPGRTNAFLVQVEDKKAILY-------NDRSVLENHH 354
Query: 312 WRAALSCI--IESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFKKLLDTNTLD 482
+ + E+ +E + + ++L + I+ATD+ + + + F + L +D
Sbjct: 355 AAESWKLLNKPENHFIENLDPAEMKRFRYLVLEYILATDLKQHFEIIMTFTERL--TEID 412
Query: 483 MRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCD 662
++++ R+L+ ++ +K ADI++P +P+ + ++W+ ++CEEF+ QGD E+ LP+T D
Sbjct: 413 VQVETDRLLIGKLLIKMADINSPTKPYGLHRQWTDRICEEFYEQGDDERRRGLPITPYMD 472
Query: 663 RDSTSI 680
R +
Sbjct: 473 RGDAQV 478
>UniRef50_Q4SI77 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 750
Score = 92.7 bits (220), Expect = 1e-17
Identities = 62/186 (33%), Positives = 94/186 (50%), Gaps = 7/186 (3%)
Frame = +3
Query: 144 IRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAA 323
I +E++A ++A HD HPG FL+AT A LY + SVLE+HH AA
Sbjct: 439 IPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYN-------DRSVLENHHAAAA 491
Query: 324 LSCIIESGLLEERPDLQEELKKHLKVL----IMATDITRQHDYLSRFK-KLLDTNT--LD 482
S + +L K + L I+ATD+ + D+L+ F K+ D N+ +D
Sbjct: 492 WSLYLSRPEFNFLVNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNSKVNDVNSPGID 551
Query: 483 MRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCD 662
+ R+LV Q+ +K ADI+ P + + +W+ + EF+ QGD E L LPV+ D
Sbjct: 552 WTNENDRLLVCQVCIKLADINGPAKIRDLHLQWTEGIVNEFYEQGDEEAKLGLPVSPFMD 611
Query: 663 RDSTSI 680
R S +
Sbjct: 612 RSSPQL 617
Score = 33.1 bits (72), Expect = 9.1
Identities = 14/27 (51%), Positives = 17/27 (62%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F+ ESGY PYHN +HA DV A+
Sbjct: 357 FSALESGYRDI-PYHNRVHAADVLHAV 382
>UniRef50_Q14432 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase A; n=27; Euteleostomi|Rep:
cGMP-inhibited 3',5'-cyclic phosphodiesterase A - Homo
sapiens (Human)
Length = 1141
Score = 92.7 bits (220), Expect = 1e-17
Identities = 59/190 (31%), Positives = 96/190 (50%), Gaps = 5/190 (2%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 815 GCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYN-------DRSVLEN 867
Query: 306 HHWRAALSCIIESGLLEERPDLQEELKKHLKVL----IMATDITRQHDYLSRFK-KLLDT 470
HH AA + + +L KH + L I+ATD+ + D++++F K+ D
Sbjct: 868 HHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDD 927
Query: 471 NTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
+D + R+LV Q+ +K ADI+ P + + +W+ + EF+ QGD E L LP++
Sbjct: 928 VGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPIS 987
Query: 651 QLCDRDSTSI 680
DR + +
Sbjct: 988 PFMDRSAPQL 997
>UniRef50_Q4N6H0 Cluster: Putative uncharacterized protein; n=1;
Theileria parva|Rep: Putative uncharacterized protein -
Theileria parva
Length = 840
Score = 91.9 bits (218), Expect = 2e-17
Identities = 60/238 (25%), Positives = 122/238 (51%), Gaps = 3/238 (1%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
L E Y++ + YHN +H V Q + C ++ + + ++ ++S + HDI HPG+
Sbjct: 596 LVEKCYNNVS-YHNQMHGVFVCQKLLCLSNFTNVYSRLSVIDRTILIISGLCHDIGHPGL 654
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLE--ERPDLQEELK 386
F I + + LA L+ + SVLE+ H + + +S L ++ +++ +
Sbjct: 655 TNAFFINSGHQLAHLFN-------DKSVLENFHCCLTFNVLRQSNLFSFLDKEEMKIVRR 707
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
K ++ LI++TD+ +++F+ + + + ++ + ++ +K +DI + C W
Sbjct: 708 KIIQ-LILSTDLEDHFQTITQFR--VRRASREFSVEGEIDTICKMLIKASDIGSSCMEWR 764
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDS-TSIPXNTNXLL*IYXSLPXITE 737
++ +WS ++ +EF+ QG E L LP+T LCD + +P + L I+ +P TE
Sbjct: 765 LTLEWSQRLVQEFYTQGLEELSLGLPITPLCDPNKHNHLPKAQSGFLAIFV-IPLYTE 821
>UniRef50_P91119 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-5; n=3; Caenorhabditis|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-5 - Caenorhabditis elegans
Length = 710
Score = 91.9 bits (218), Expect = 2e-17
Identities = 58/203 (28%), Positives = 98/203 (48%), Gaps = 3/203 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN H V AM L+ S AF + +E +A +S + HD+ H G N ++
Sbjct: 484 YHNWAHGWSVAHAMFATLMN-SPDAFTK-LEALALYVSCLCHDLDHRGKNNAYMKTMSTP 541
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVL---IMAT 416
LA +Y + SV+E HH+ ++ + + G + E+ KK L ++ I+AT
Sbjct: 542 LASIY--------STSVMERHHFNQTVTILQQDGHNILKSLSSEDYKKTLSLIKHCILAT 593
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+ ++ +LD NT D+ QEHR+L + + D+ +PW++ + +
Sbjct: 594 DLALFFSNKAKLNVILDNNTFDINRQEHRLLTQAVMMTGCDLVASAKPWNIQTETVKVIF 653
Query: 597 EEFFRQGDYEKMLDLPVTQLCDR 665
EEF+ QGD E++ + DR
Sbjct: 654 EEFYDQGDAERLSGKEPIPMMDR 676
>UniRef50_Q3KVL8 Cluster: High-affinity phosphodiesterase; n=4;
Eukaryota|Rep: High-affinity phosphodiesterase -
Cryptococcus neoformans var. neoformans
Length = 555
Score = 72.1 bits (169), Expect(2) = 2e-17
Identities = 63/211 (29%), Positives = 104/211 (49%), Gaps = 32/211 (15%)
Frame = +3
Query: 135 RAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHW 314
R +RP +I+A L++A+ HD+ HPG++ F++ +C L+ +Y E+ SVLE+ H
Sbjct: 311 REIMRPQDILAVLIAAMGHDVGHPGLSNAFMV-SC-PLSQVY-------EDKSVLENMHC 361
Query: 315 RAALSCIIE--SGLLEERPDL-----------QEELKKHLKVLIMATDITRQHDYLSRFK 455
+ + + G L ER Q+ ++ L I+ATD++ ++ R K
Sbjct: 362 MLVVQLLRKYGFGFLIERTKSSSGEQAVSNLDQKSFRQVLYSSILATDMSLHFAWVQRLK 421
Query: 456 KLLD--TNTLDMRIQEHRILVLQIALKCADISNP-----------------CRPWSVSQK 578
+ D + +++ RIL+ Q +KCADISNP RP VSQ
Sbjct: 422 EFDDRLKSGEAGAVEDERILICQALIKCADISNPVSLIESTVRLSFDTHLQSRPIDVSQH 481
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQLCDRDS 671
WS + EE+ +Q E+ L LPV+ + D+
Sbjct: 482 WSSVLLEEWAKQASLEQDLSLPVSVVASADA 512
Score = 39.9 bits (89), Expect(2) = 2e-17
Identities = 15/24 (62%), Positives = 18/24 (75%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFL 119
YH+ NPYHN +HA DV QA + FL
Sbjct: 248 YHAPNPYHNYVHALDVLQATYTFL 271
>UniRef50_Q01C40 Cluster: Cyclic GMP phosphodiesterase; n=1;
Ostreococcus tauri|Rep: Cyclic GMP phosphodiesterase -
Ostreococcus tauri
Length = 674
Score = 91.5 bits (217), Expect = 2e-17
Identities = 75/243 (30%), Positives = 115/243 (47%), Gaps = 29/243 (11%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
ES Y NPYH HA DV + ++L + + +EI + L++A+ HD+ HPGV
Sbjct: 302 ESMYRD-NPYHCFKHAFDVAHTTYLYILAVKDQVEMSQLEIFSLLVAALVHDLDHPGVTN 360
Query: 219 GFLIATCNHLADLYR---ILEGT--SENFSVLESHHWRAALSCIIESGLLEERPD----- 368
+LIAT + +A Y +LE S F++ +++ LS E R
Sbjct: 361 AYLIATRDSIAMTYNDESVLENLHLSRFFTLCQNNEDANILSAFDEDTYSVVRRTIIGCV 420
Query: 369 LQEELKKHLKV---------LIMATDITRQ---HDYLSRFKK--LLDTN-----TLDMRI 491
L ++ H K+ L T+I R S K +LD + +
Sbjct: 421 LHTDMAHHFKLVSRMNEMVSLGRKTEIIRSPIGSPMSSPIKSCVVLDREGDPSVAVSFKT 480
Query: 492 QEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDS 671
E R L+L + L CADISN +P + KW+ +V EEFF QGD E+ + V+ + DR++
Sbjct: 481 DEERQLMLNVLLHCADISNAVKPNELCVKWASRVLEEFFNQGDRERAKGMSVSPMMDRET 540
Query: 672 TSI 680
TS+
Sbjct: 541 TSV 543
>UniRef50_A6S8A0 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 945
Score = 91.1 bits (216), Expect = 3e-17
Identities = 75/228 (32%), Positives = 112/228 (49%), Gaps = 29/228 (12%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQ-GSIRAF------------------IRPVEIIAC 170
Y+S PYHN H DV QA+ FL++ GS+ + IRP + +
Sbjct: 372 YNSFVPYHNFRHVVDVLQAIFHFLVRLGSLPEYPPSPDGTTSQKSSPIAELIRPFDALTL 431
Query: 171 LLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL 350
+++AI HD+ HPGVN FL+ LA LY + SVLES H AA S I+
Sbjct: 432 MITAIGHDVGHPGVNNAFLVHLNAPLAQLYN-------DRSVLESFHC-AAYSQILRRHW 483
Query: 351 LEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFKKLLD--------TNTLDMR-IQEH 500
L +E +HL + I+ATD+ DY+ + L + T+ + R I++
Sbjct: 484 LAA---FEERDMRHLMISTILATDMGLHFDYMKKLGYLQEKLHENGGVTDGWNGRTIEDQ 540
Query: 501 RILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLP 644
R L + +KCADISN R + + +W+ + +EF RQ E+ L +P
Sbjct: 541 RTLACSLLIKCADISNVARKFDTATRWTEILTDEFARQASMEQDLGIP 588
>UniRef50_Q3SBD3 Cluster: Sperm phosphodiesterase 5; n=1;
Strongylocentrotus purpuratus|Rep: Sperm
phosphodiesterase 5 - Strongylocentrotus purpuratus
(Purple sea urchin)
Length = 949
Score = 90.6 bits (215), Expect = 4e-17
Identities = 61/211 (28%), Positives = 103/211 (48%), Gaps = 5/211 (2%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M ++ G +R + +EI A +++ + HD+ H G N F + T +
Sbjct: 617 YHNWRHAFNVAQTMFSIVMTGKLRKLLTDLEIFALIVACLCHDLDHRGTNNTFQVKTSSP 676
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLE-ERPDLQEELKKHLKVLIMAT 416
L+ LY GT S +E HH+ + + G + E PD E + L+ I++T
Sbjct: 677 LSLLY----GT----STMEHHHFDHCIMILNSEGNNIFEFMSPDDYREAIRMLESAILST 728
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+ + F KL++ +E + L+ + + D+S +PW V QK + V
Sbjct: 729 DLAIYFKKRADFFKLVEKGEHTWDNEEKKGLLRGMLMTACDVSAIAKPWLVQQKVAELVF 788
Query: 597 EEFFRQGDY--EKMLDLPVTQLCDRDSTSIP 683
EFF+QGD EK+ + P+ + + +P
Sbjct: 789 SEFFQQGDLEREKLKEEPMAMMDRKKKDELP 819
>UniRef50_Q2V2M6 Cluster: CGMP-specific phosphodiesterase; n=3;
Plasmodium|Rep: CGMP-specific phosphodiesterase -
Plasmodium falciparum
Length = 884
Score = 90.6 bits (215), Expect = 4e-17
Identities = 61/217 (28%), Positives = 103/217 (47%), Gaps = 3/217 (1%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
K F Y++ PYH S+HA V L + I ++ +S++ HD
Sbjct: 594 KKFLFRICSYYNDIPYHTSLHAAQVAHFSKSMLFMLDMNHKISAIDEFCLHISSLCHDTG 653
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERP-DL 371
HPG+N FLI + N+LA Y ++N SVLE++H + + E P +
Sbjct: 654 HPGLNNYFLINSENNLALTY------NDN-SVLENYHCSLLFKTLKNPNYNIFEHYPYHI 706
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNP 551
KK++ I++TD+ +Y+S F+ + D + + + LK +DI +
Sbjct: 707 FISCKKNIIKAILSTDMKNHFEYISDFRTSKEFIDYDNLSNDQIWQIFCLILKASDIGHS 766
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCD 662
W+ +W++K+ EEF+ QG EK L++ + LCD
Sbjct: 767 TLEWNKHLEWTLKINEEFYLQGLLEKSLNIQNSFLCD 803
>UniRef50_A2EY05 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 922
Score = 90.6 bits (215), Expect = 4e-17
Identities = 55/200 (27%), Positives = 99/200 (49%), Gaps = 3/200 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
++ PYHN HA DV Q + + + ++ E+++ L++A+ HD+ H G N + I
Sbjct: 667 YNNPPYHNWTHAIDVLQYVSYEIKLTNSHNHLKSQELLSVLVAALCHDVGHQGFNNAYNI 726
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIE--SGLLEERPDLQ-EELKKHLKV 401
L++ + SV+E+ H A+ + E + L D + +
Sbjct: 727 NVKTPFGILFK-------DTSVMETFHCAMAIKILQEDDTNLFYSLNDNDLSNVWSWIIH 779
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ + + + + LDM + R+ +++ +K ADISN RP+ ++ KW
Sbjct: 780 LILATDMAKHFKLIKEMNDTISSRNLDMESENDRLCCMEMIMKVADISNVSRPFFIADKW 839
Query: 582 SVKVCEEFFRQGDYEKMLDL 641
+ +EF+RQGD EK +L
Sbjct: 840 CDVLQDEFWRQGDMEKQHEL 859
>UniRef50_Q13370 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase B; n=26; Euteleostomi|Rep:
cGMP-inhibited 3',5'-cyclic phosphodiesterase B - Homo
sapiens (Human)
Length = 1112
Score = 89.8 bits (213), Expect = 8e-17
Identities = 60/192 (31%), Positives = 99/192 (51%), Gaps = 7/192 (3%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 800 GCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYN-------DRSVLEN 852
Query: 306 HHWRAALSCII---ESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFK-KLLDT 470
HH +A + + E L ++ + + L + I+ATD+ + D+L+ F K D
Sbjct: 853 HHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDV 912
Query: 471 NT--LDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLP 644
N+ ++ + R+LV Q+ +K ADI+ P + + KW+ + EF+ QGD E L LP
Sbjct: 913 NSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLP 972
Query: 645 VTQLCDRDSTSI 680
++ DR S +
Sbjct: 973 ISPFMDRSSPQL 984
Score = 33.5 bits (73), Expect = 6.9
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E+GY PYHN IHATDV A+
Sbjct: 724 FRALENGYRDI-PYHNRIHATDVLHAV 749
>UniRef50_Q4T098 Cluster: Chromosome undetermined SCAF11274, whole
genome shotgun sequence; n=4; Tetraodontidae|Rep:
Chromosome undetermined SCAF11274, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 601
Score = 89.4 bits (212), Expect = 1e-16
Identities = 60/189 (31%), Positives = 95/189 (50%), Gaps = 5/189 (2%)
Frame = +3
Query: 129 SIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESH 308
S + ++ +EI A + +A HD H G F I T + ++ LY + +V E+H
Sbjct: 256 SFQHWLTELEIFATIFAAAIHDYEHTGTTNNFHIQTRSDISLLYN-------DHAVQENH 308
Query: 309 HWRAA---LSCIIESGLLEE-RPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDT-N 473
H A L ++ +L D EL+ + +++ATD++ + + K LL
Sbjct: 309 HVSAVYRLLQTNDDTNILSNLSKDDWRELRALVVEMVLATDMSCHFEQIKVMKGLLQQPE 368
Query: 474 TLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ 653
+D + L + L ADIS+P +PWS+ +W+ + EEFFRQGD E L LP +
Sbjct: 369 AID------KAKALSLLLHTADISHPAKPWSLHHRWTFSLLEEFFRQGDKEVELGLPFSP 422
Query: 654 LCDRDSTSI 680
LCDR ST +
Sbjct: 423 LCDRKSTMV 431
Score = 37.5 bits (83), Expect = 0.42
Identities = 17/30 (56%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQ 125
E GY NPYHN HA DVTQ +H LL+
Sbjct: 181 EMGYSKHRNPYHNLTHAADVTQTIHYLLLK 210
>UniRef50_Q4SVG8 Cluster: Chromosome undetermined SCAF13758, whole
genome shotgun sequence; n=4; Tetraodontidae|Rep:
Chromosome undetermined SCAF13758, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 928
Score = 88.2 bits (209), Expect = 2e-16
Identities = 59/214 (27%), Positives = 102/214 (47%), Gaps = 4/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ Y + YHN HA + Q+M L G ++ + +E++A +++ ++HD+ H GVN
Sbjct: 663 KKNYRKSVAYHNWRHAFNTAQSMFALLKSGRLQNELTDLEVLALMIATLSHDLDHRGVNN 722
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK 398
++ + + LA LY S +E HH+ L + G +E K LK
Sbjct: 723 SYIQRSEHPLAQLY--------CHSTMEHHHFDHCLMILNSPGNQILSGLSLDEYKSTLK 774
Query: 399 VL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I+ATD+ F +L + + HR L+ + + DIS +PW V
Sbjct: 775 MIERAILATDLALHMKRRGEFFELTKNSQFRWEDEGHRDLLRSMLMTACDISAITKPWPV 834
Query: 570 SQKWSVKVCEEFFRQGDYEKM-LDLPVTQLCDRD 668
Q+ + V EFF QGD E+ L++ + L +R+
Sbjct: 835 QQRIAELVATEFFEQGDKERRELNIEPSDLMNRE 868
>UniRef50_Q4RSB8 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF15000, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 737
Score = 88.2 bits (209), Expect = 2e-16
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 7/187 (3%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 413 GCLSGLIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYN-------DRSVLEN 465
Query: 306 HHWRAALSCIIESGLLEERPDLQEELKKHLKVL----IMATDITRQHDYLSRFKKLL--D 467
HH AA + + +L K + L I+ATD+ + D+L+ F + D
Sbjct: 466 HHAAAAWNLFMSHPEYNFLVNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKVGDD 525
Query: 468 TNT-LDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLP 644
+T +D + R+LV Q+ +K AD++ P + + +W+ + EF++QGD E L LP
Sbjct: 526 PSTGIDWSNENDRLLVCQMCIKLADVNGPLKCKDLHLQWTEGIVNEFYQQGDEESTLGLP 585
Query: 645 VTQLCDR 665
++ DR
Sbjct: 586 ISPFMDR 592
Score = 33.1 bits (72), Expect = 9.1
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E+GY PYHN IHATDV A+
Sbjct: 337 FHALENGYRDI-PYHNRIHATDVLHAV 362
>UniRef50_UPI0000F1D4E2 Cluster: PREDICTED: similar to
Phosphodiesterase 5A; n=4; Danio rerio|Rep: PREDICTED:
similar to Phosphodiesterase 5A - Danio rerio
Length = 905
Score = 87.8 bits (208), Expect = 3e-16
Identities = 60/214 (28%), Positives = 105/214 (49%), Gaps = 4/214 (1%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
Y S YHN HA Q M L +++ + +E++A ++++++HD+ H GVN ++
Sbjct: 641 YRSNVVYHNWSHALRTAQCMFAMLQTKELKSNLSSLEVLALMIASLSHDLDHRGVNNSYI 700
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVL- 404
+ LA LY G S LE HH+ L + G E L+++
Sbjct: 701 QRSNQPLAQLY----GQSS----LEHHHYDMCLLILNNPGSQILSSLSVNEYMACLQMIE 752
Query: 405 --IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
I+ATD+ + ++F KL + N+ + + HR L+ + + +DI +PW V ++
Sbjct: 753 KNILATDLAIFFEKRTKFFKLAENNSCLWKDEGHRELLRSMLMTASDICAITKPWPVQKR 812
Query: 579 WSVKVCEEFFRQGDYEKM-LDLPVTQLCDRDSTS 677
+ V EF+ QGD EK L++ + DR++ S
Sbjct: 813 IAELVATEFYAQGDREKRELNIQPIDVMDRENAS 846
>UniRef50_UPI000023CCA1 Cluster: hypothetical protein FG06914.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG06914.1 - Gibberella zeae PH-1
Length = 886
Score = 86.6 bits (205), Expect = 7e-16
Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 10/178 (5%)
Frame = +3
Query: 138 AFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWR 317
+ I P E + L++AI HD+ HPGVN GFL+ LA LY + SVLES H
Sbjct: 355 SLITPFEALTLLITAIGHDVGHPGVNNGFLVTLNAPLAQLY-------NDRSVLESFHC- 406
Query: 318 AALSCIIESGLLEERPDLQEELK-KHLKV-LIMATDITRQHDYLSRF----KKLLDTNTL 479
AA S I L P E+ K ++L + I+ATD+ DY+ + ++L +NT
Sbjct: 407 AAYSQI----LRRYWPSAFEDTKMRNLMISSILATDMGLHFDYMKKLGDVQERLQASNTT 462
Query: 480 D----MRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDL 641
D +I+E++ L + +KCADISN R ++ +W+ + EEF RQ E L +
Sbjct: 463 DGWNGRQIEENKSLACSLLIKCADISNVARSHEIALQWTYILSEEFSRQASMESELSI 520
>UniRef50_Q8IKD3 Cluster: Cyclic nucleotide phosphodiesterase,
putative; n=1; Plasmodium falciparum 3D7|Rep: Cyclic
nucleotide phosphodiesterase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 813
Score = 86.2 bits (204), Expect = 9e-16
Identities = 62/213 (29%), Positives = 99/213 (46%), Gaps = 9/213 (4%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+LF L + + NPYHN+ H V C +++ +I L+++IAHD+
Sbjct: 441 QLFLLLINSMYFPNPYHNANHGATVCHLSKCLAHITDYDSYLNNTYMICYLIASIAHDVG 500
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG----LLEERPD 368
HPG +L T NH IL + S+LE++H S + G + E
Sbjct: 501 HPGKTNSYLSET-NH------ILSIRYNDMSILENYHCSITFSILQLIGFDFLINNEDTK 553
Query: 369 LQEE-----LKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKC 533
L E+ ++K + LI++TD+ +Y+ FKK + D+ I + I +K
Sbjct: 554 LVEKNNYTNMRKFIIELIISTDMKLHFEYVDIFKKRKKSQNFDIS-DTDAINLGTINIKL 612
Query: 534 ADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKM 632
ADI + C W KW++ V EEFF Q E++
Sbjct: 613 ADIGHTCLKWKDHAKWTMLVSEEFFSQKRVEEL 645
>UniRef50_A0EHP5 Cluster: Chromosome undetermined scaffold_97, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_97, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 908
Score = 86.2 bits (204), Expect = 9e-16
Identities = 54/209 (25%), Positives = 104/209 (49%), Gaps = 4/209 (1%)
Frame = +3
Query: 39 ESGYHST-NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E Y+S NP+HN H V A + + + ++ E A +LS++ HDI H G
Sbjct: 654 EERYNSRRNPFHNFEHGFTVAHACYYMIKNKLLDEYLDQTEQFAAILSSLCHDIDHTGRT 713
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQ-EELK 386
GF +A + LA Y + SVLE+HH A + +L Q ++++
Sbjct: 714 NGFEVARMSKLAVRYN-------DESVLENHHAAMAFKIMQREKYNILSNLSQEQFQKVR 766
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ + I+ATD+ + D +S + +++ + + ++ + + D++ P + +
Sbjct: 767 RFMVSNILATDMKKHFDLVSSLEIKYKNGEMNIVNMDTKRVLSGLIVHTCDLTQPTKRFE 826
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQ 653
+++KWS+++ EF Q + E++L LP+TQ
Sbjct: 827 ITKKWSIRIQNEFDNQVEEERLLGLPITQ 855
>UniRef50_Q2H9G5 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized protein
- Chaetomium globosum (Soil fungus)
Length = 894
Score = 86.2 bits (204), Expect = 9e-16
Identities = 76/249 (30%), Positives = 111/249 (44%), Gaps = 29/249 (11%)
Frame = +3
Query: 42 SGYHSTNPYHNSIHATDVTQAMHCFLLQ--------------------GSIRAFIRPVEI 161
+ Y++ PYHN H DV QA FL++ I +RP E
Sbjct: 333 AAYNTFVPYHNFRHVVDVLQATFHFLVRIGALPPYRSADGLLSAACRKSPIAELLRPFEA 392
Query: 162 IACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIE 341
+ L++AI HD+ HPGVN GFL+ LA LY + SVLES H AA S I+
Sbjct: 393 LTLLITAIGHDVGHPGVNNGFLVTLNAPLAQLY-------NDRSVLESFHC-AAYSQILR 444
Query: 342 SGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFKKLL-------DTNTLDMRIQ- 494
E D + +HL + I+ATD+ DY+ + L T D ++
Sbjct: 445 RYWPETFDDSK---MRHLMISSILATDMGLHFDYMRKLGDLQGKLRPNNSTEDWDEGVKN 501
Query: 495 EHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDST 674
E + L + +KCADISN R + +W + EEF RQ E L++ + + +
Sbjct: 502 EQKALTCALLIKCADISNVTRRHDAAIQWMKILSEEFSRQATMENELEIKTSLMSEPKQD 561
Query: 675 SIPXNTNXL 701
+ T+ L
Sbjct: 562 KLSLTTSQL 570
>UniRef50_UPI000150A9A4 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 929
Score = 85.8 bits (203), Expect = 1e-15
Identities = 69/271 (25%), Positives = 125/271 (46%), Gaps = 7/271 (2%)
Frame = +3
Query: 21 KLFTLFESGYHST-NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDI 197
K L + Y NP+HN HA V+ A + F+ + ++ +E L S++ HD+
Sbjct: 642 KFLQLLQHKYDKRQNPFHNFQHAIAVSHATYFFINAKFLARYLDYLEQFTLLFSSLGHDV 701
Query: 198 FHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQ- 374
H G F +AT + LA + + SVLE+HH I + + E+ +
Sbjct: 702 SHTGRTNAFEVATLSKLAIKF-------NDESVLENHHSSTLFKIIQKHNIFEQLSNEDV 754
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFK-KL--LDTNTLDM-RIQEHRILVLQIALKCADI 542
+ ++K+ I++TD+ + + +F+ KL L D+ + + + L+ + AD+
Sbjct: 755 KNIRKYCISNILSTDMKKHQELTKQFEIKLTYLKQEGTDLIKSEADKKLMCGFLVHVADL 814
Query: 543 SNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT-QLCDRDSTSIPXNTNXLL*IYXS 719
+ P + + ++++WS+++C+EF Q E+ L LPVT L +S I
Sbjct: 815 TGPTKCFELAKEWSMRICKEFTLQVQEEEHLGLPVTPYLVGLESMEIISKQEGNFAKIIV 874
Query: 720 LPXITEWNRFLDSKLSXEMXANXXYNEVQWE 812
LP + + F + +M N N QWE
Sbjct: 875 LPLYSVLSEFAGPEFK-QMVKNCENNISQWE 904
>UniRef50_UPI0000588CD9 Cluster: PREDICTED: hypothetical protein; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 701
Score = 85.8 bits (203), Expect = 1e-15
Identities = 61/218 (27%), Positives = 93/218 (42%), Gaps = 3/218 (1%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F L ++ P+HN HA DV M LL R E+ A +I HD+ H
Sbjct: 428 FILTVRKHYRLVPFHNFCHAFDVCHCMFMILLHSEGR--FTDEEMYAMFFGSICHDMDHR 485
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL---LEERPDLQE 377
G+ F L LY + S++ESHH+ +S + G PD +
Sbjct: 486 GLTNSFHAKFGTPLGKLY--------SSSIMESHHFAMIVSILHREGFNVFSHLPPDTFK 537
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++ ++ +IM+TD+T KLL T D I HR + + + D+ +
Sbjct: 538 KIVDLIQDIIMSTDLTNFFPNHKELSKLLVAQTFDWTIDHHRWSIRNMCMTACDLCASTK 597
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDS 671
W + Q+ + EEF+ QGD EK Q+ DRD+
Sbjct: 598 MWPIQQQIVECLYEEFYSQGDIEKERGETPIQMLDRDN 635
>UniRef50_A0CZ03 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_31, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 692
Score = 85.8 bits (203), Expect = 1e-15
Identities = 64/217 (29%), Positives = 110/217 (50%), Gaps = 5/217 (2%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEI--IACLLSAIA-HDIFHPGVN 215
GY NPYHN +HA DV Q + FLL I ++ IAC+L A A HD HPG+
Sbjct: 427 GYQD-NPYHNRVHAQDVAQTCN-FLLNRCKFIEIGQLDEQDIACVLIAGAIHDYGHPGLT 484
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHH--WRAALSCIIESGLLEERPDLQEELKK 389
FLI + N LA Y + E F + W + I ES ++ ++E +
Sbjct: 485 NAFLINSKNELALTYND-QSVLEMFHPSQCFKIAWTNQKANIFESLTFQKYRRIRESIIS 543
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++++TD+ L+ + + ++ + L + + + +D+SNP + + +
Sbjct: 544 ----MVLSTDMAHHASELAITNSRVAAPDFEPYGKDKQRL-MDLVVHSSDVSNPTKSFEI 598
Query: 570 SQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
++W+ +V EF+ QGD E+ L LP++ LC+R +T++
Sbjct: 599 YKQWTERVLTEFWLQGDKERELGLPISYLCNRYTTNM 635
>UniRef50_A5K353 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=5; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 803
Score = 85.0 bits (201), Expect = 2e-15
Identities = 63/213 (29%), Positives = 99/213 (46%), Gaps = 9/213 (4%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+LF L + + NPYHN+ H V C + +I L+++IAHD+
Sbjct: 420 QLFLLLINNMYFPNPYHNANHGATVCHLSKCLAHITDFDKSLNNTYMICYLIASIAHDVG 479
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG----LLEERPD 368
HPG +L T NH IL + S+LE++H S + G + E
Sbjct: 480 HPGKTNAYLSET-NH------ILSIRYNDMSILENYHCSITFSILQLIGHDFLINSEDTK 532
Query: 369 LQEE-----LKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKC 533
L E+ L+K + LI++TD+ +Y+ FKK + D+ ++ I + I +K
Sbjct: 533 LVEKNSYANLRKFIIELIISTDMKLHFEYVDIFKKRKRSENFDISDRD-AINLGTINIKV 591
Query: 534 ADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKM 632
ADI + C W KW++ V EEFF Q E++
Sbjct: 592 ADIGHTCLKWRDHAKWTMLVSEEFFSQKKVEEL 624
>UniRef50_UPI00015B4531 Cluster: PREDICTED: similar to cyclic GMP
stimulated phosphodiesterase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to cyclic GMP
stimulated phosphodiesterase - Nasonia vitripennis
Length = 1684
Score = 84.2 bits (199), Expect = 4e-15
Identities = 65/228 (28%), Positives = 111/228 (48%), Gaps = 9/228 (3%)
Frame = +3
Query: 27 FTLF-ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIR----AFIRPVEIIACLLSAIAH 191
F L+ + GY PYHN +HA V A +LL ++ ++ ++ + L+S + H
Sbjct: 420 FILYVKKGYRDA-PYHNWMHAFSV--AHFAYLLMKNLNLVRDGYMTSLQALVFLVSCLCH 476
Query: 192 DIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDL 371
DI H G N F LA LY S SV+E HH ++ CI+ + +L
Sbjct: 477 DIDHRGTNNSFQTKCGTILASLY------SSEGSVMERHHLAQSM-CILNTEGCNIFENL 529
Query: 372 Q-EELKKHLKVL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCAD 539
EE + L +L I+ATD+ H ++ + D +H+ ++ + + C D
Sbjct: 530 SSEEYSEALDLLRNNILATDLA-SHFRSVEEQRDVTKQGYDKNNPKHQKILHAMFMTCCD 588
Query: 540 ISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+++ + W VS++ + ++ +EFF QGD EK + ++ DR+ SIP
Sbjct: 589 LNDQTKNWRVSKQTAEQIYDEFFSQGDLEKSMGTAPIEMMDRERASIP 636
>UniRef50_Q17L35 Cluster: Cgmp-dependent 3,5-cyclic
phosphodiesterase; n=2; Culicidae|Rep: Cgmp-dependent
3,5-cyclic phosphodiesterase - Aedes aegypti
(Yellowfever mosquito)
Length = 502
Score = 83.8 bits (198), Expect = 5e-15
Identities = 65/227 (28%), Positives = 101/227 (44%), Gaps = 6/227 (2%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSI--RAFIRPVEIIACLLSAIAHD 194
+ L + GY T PYHN HA V + ++ + I ++ + L++A HD
Sbjct: 224 RFILLVQKGYRDT-PYHNWWHAFSVAHFAYSLMVNLKLIENGVITKMQGFSFLIAAFCHD 282
Query: 195 IFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQ 374
+ H G + + + + LA LY S SV E HH A+ CI+ + L
Sbjct: 283 LDHRGTSNTYQTQSSSPLARLY------SSEGSVNERHHLSQAI-CILNDSSSKILDSLS 335
Query: 375 -EELKK---HLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADI 542
EE K+ L+ LI+ATD+ + K+L N + Q L+L + + C D+
Sbjct: 336 TEEFKECIDFLRDLILATDLANHFRIMPHLKRLRPENLGEGSNQR---LLLSLMITCCDL 392
Query: 543 SNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
S+ + W Q + V EFF +GD EK + L + DR IP
Sbjct: 393 SDQVKSWKTVQHVAHLVYAEFFAEGDLEKQMGLRPNAMMDRKKACIP 439
>UniRef50_A5JZK3 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase,
putative; n=7; Plasmodium|Rep: 3',5'-cyclic-nucleotide
phosphodiesterase, putative - Plasmodium vivax
Length = 783
Score = 83.4 bits (197), Expect = 7e-15
Identities = 58/214 (27%), Positives = 106/214 (49%), Gaps = 3/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ GY++ PYHN IHA V + + + +R E+ A LL+A+ HDI H G
Sbjct: 492 KEGYNNV-PYHNCIHAAMVAEQCNILVNNLDTANILRDNEMAAFLLAALGHDIGHFGRTN 550
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FL + N L+ +Y + S+LE++H + + E L++
Sbjct: 551 LFLKNSSNFLSVIYN-------DKSILENYHCSYLFHILFKEQNNIFKNESAKTVLNLRQ 603
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
+ +I+ATD+++ L++F+ + + + I+++ IL L++ +K AD+S+ C WS
Sbjct: 604 EIIQVILATDMSKHIKILAQFR--IKSIKIRSYIEKNIILCLKMIIKAADLSHNCVDWSE 661
Query: 570 SQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDS 671
W ++ EF+ +GD + + L DR+S
Sbjct: 662 HYLWVKRLVNEFYYEGDEQLEKGYQINPLFDRNS 695
>UniRef50_O94034 Cluster: Nucleotide phosphodiesterase; n=4;
Saccharomycetales|Rep: Nucleotide phosphodiesterase -
Candida albicans (Yeast)
Length = 571
Score = 69.3 bits (162), Expect(2) = 7e-15
Identities = 46/164 (28%), Positives = 84/164 (51%), Gaps = 7/164 (4%)
Frame = +3
Query: 135 RAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHW 314
+A + P++ + L++A+ HD+ HPG F+I A LY + SVLES+H
Sbjct: 331 KASLNPIQTLGLLVAALGHDVGHPGTTNDFMIKFSAPTALLYN-------DRSVLESYHA 383
Query: 315 RAALSCIIE-------SGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTN 473
++ ++ + +EE+ +L ++ + I+ATD+ ++Y++R K N
Sbjct: 384 SLFINKVLRICWPDLLTCTIEEKSELT--IRSLIISSILATDMGEHNEYVNRLKSFKTHN 441
Query: 474 TLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEF 605
+ + L+ + +KCADISN RP VS +W++ + EF
Sbjct: 442 EI-LNHDNTVKLISALLIKCADISNVTRPLRVSAQWAMVLSREF 484
Score = 34.3 bits (75), Expect(2) = 7e-15
Identities = 18/38 (47%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQ-GSIRAFIRPVE 158
Y + NP+HN HA DV QA FL++ GS+ F + VE
Sbjct: 267 YKNGNPFHNFRHAVDVLQACFHFLIRLGSLPKFKQFVE 304
>UniRef50_Q7QRM3 Cluster: GLP_481_5888_1773; n=1; Giardia lamblia ATCC
50803|Rep: GLP_481_5888_1773 - Giardia lamblia ATCC 50803
Length = 1371
Score = 74.5 bits (175), Expect(2) = 1e-14
Identities = 52/171 (30%), Positives = 85/171 (49%), Gaps = 9/171 (5%)
Frame = +3
Query: 135 RAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHW 314
+A IRPV+ +A L ++ HD+ H G++ F I T N LA LY E E+ S H
Sbjct: 1125 QALIRPVDFLALLFGSLCHDLGHTGIDNLFCINTENALALLYND-EAPLEHAHATLSWHI 1183
Query: 315 RAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQ 494
++ + P E + +I+ATD++ ++L R + L L ++I
Sbjct: 1184 ITQMAVYFK----HFTPCQYREFRALFLEIILATDMSTHFNFLRRLESL--DEDLIIKIL 1237
Query: 495 EH---------RILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGD 620
EH R +L++ +K D+SNPCRP +S +++V + EF+ GD
Sbjct: 1238 EHHNDSEIALLRWYILKVCIKFGDLSNPCRPIEISTRYAVALMNEFWSLGD 1288
Score = 28.3 bits (60), Expect(2) = 1e-14
Identities = 15/28 (53%), Positives = 18/28 (64%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLL 122
ES Y ST YHN +HA DV Q M ++L
Sbjct: 1059 ESSYTSTL-YHNKLHAADVAQ-MSMYML 1084
>UniRef50_Q0V6F8 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 953
Score = 80.2 bits (189), Expect = 6e-14
Identities = 69/228 (30%), Positives = 106/228 (46%), Gaps = 27/228 (11%)
Frame = +3
Query: 42 SGYHSTNPYHNSIHATDVTQAMHCFLLQ------------------GSIRAFIRPVEIIA 167
+ Y+ YHN H DV QA+ FL++ I ++P + +
Sbjct: 340 TAYNEFVKYHNFRHVVDVLQALFHFLVRIGTLLPYPPNDSSGLLPKSPIAELLKPFDALT 399
Query: 168 CLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG 347
L+SAI HD+ HPGVN FL+A LA LY + SVLES H AA S I+
Sbjct: 400 LLISAIGHDVGHPGVNNAFLVALNAPLAQLY-------NDRSVLESFHC-AAYSQILRRY 451
Query: 348 LLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLL--------DTNTLDMRI-QEH 500
+ D ++K + I+ATD+ Y++ L DT+ + ++ +E
Sbjct: 452 WPQAFSD--SAMRKLMINNILATDMGLHFKYMTDLGNLQQKIAHDQGDTDGWNSKMKEEQ 509
Query: 501 RILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLP 644
+ L + +KCADI N R + + KW+ + +EF QG E+ L +P
Sbjct: 510 KDLACGVLIKCADICNVARKFDTAAKWANILTDEFSNQGIMEQELQMP 557
>UniRef50_P30645 Cluster: Probable 3',5'-cyclic phosphodiesterase
pde-2; n=5; Eumetazoa|Rep: Probable 3',5'-cyclic
phosphodiesterase pde-2 - Caenorhabditis elegans
Length = 859
Score = 80.2 bits (189), Expect = 6e-14
Identities = 59/219 (26%), Positives = 103/219 (47%), Gaps = 5/219 (2%)
Frame = +3
Query: 42 SGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQG 221
+GY PYHN HA VT L +IR + +E ++ L++ + HDI H G
Sbjct: 414 AGYRPV-PYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNS 472
Query: 222 FLIATCNH--LADLYRILEGTSENFSVLESHHWRAALSCI--IESGLLEERPDLQ-EELK 386
F + + L+ LY S SVLE HH+ + + E +LE P +
Sbjct: 473 FQMQSLQKTPLSVLY------STEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIV 526
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
++ +I+ATDI+ R K ++ M +HR L++ + + +D+S+ + +
Sbjct: 527 NTIREVILATDISAHLRKQERIKTMISEGYNPMSF-DHRYLLMCLVMTASDLSDQAKNFH 585
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+++ + + EFF QGD E L + ++ DR + +P
Sbjct: 586 NAKRIAENIYLEFFAQGDLELQLGVKPLEMMDRTNAYVP 624
>UniRef50_UPI0000D8B81A Cluster: UPI0000D8B81A related cluster; n=1;
Mus musculus|Rep: UPI0000D8B81A UniRef100 entry - Mus
musculus
Length = 746
Score = 79.8 bits (188), Expect = 8e-14
Identities = 60/211 (28%), Positives = 96/211 (45%), Gaps = 10/211 (4%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 495 YHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSA 554
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 555 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 607
Query: 417 DITRQHDYLSRFKKLL------DTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
D+T D F +++ D ++ L+ + + D+ +PW +S++
Sbjct: 608 DLTLYFDEKILFSRIILQCPLHDGEAEPGHYKQCDPLLRSMLMTACDLGAVTKPWEISRQ 667
Query: 579 WSVKVCEEFFRQGDYEKM-LDLPVTQLCDRD 668
+ V EFF QGD E+ L L + + DR+
Sbjct: 668 VAELVTSEFFEQGDRERSELKLTPSAIFDRN 698
>UniRef50_A4RPY9 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 862
Score = 79.8 bits (188), Expect = 8e-14
Identities = 68/198 (34%), Positives = 97/198 (48%), Gaps = 29/198 (14%)
Frame = +3
Query: 42 SGYHSTNPYHNSIHATDVTQAMHCFLLQ-GSIRAF--------------------IRPVE 158
+ Y++ PYHN H DV QA FL+Q GS+ F ++P E
Sbjct: 356 AAYNNFVPYHNFRHVIDVLQATFNFLVQIGSLPPFPPRSDDYIATPQPTSPIATLMKPFE 415
Query: 159 IIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCII 338
+ L++A+ HD+ HPGVN GFL+ LA LY + SVLES H AA S I+
Sbjct: 416 ALTLLVTAVGHDVGHPGVNNGFLVTLNAPLAQLY-------NDRSVLESFHC-AAYSQIL 467
Query: 339 ESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRF----KKLLDTNTLD----MRIQ 494
DLQ ++ + I+ATD+ DY+ + +KL + N ++ I+
Sbjct: 468 RRYWPAAFEDLQ--MRNLMISSILATDMGLHFDYMKKLGDLQEKLHENNAIEGWNGRVIE 525
Query: 495 EHRILVLQIALKCADISN 548
EH+ L I +KCADISN
Sbjct: 526 EHKALACAILIKCADISN 543
>UniRef50_Q7YYN8 Cluster: Phosphdiesterase, possible; n=2;
Cryptosporidium|Rep: Phosphdiesterase, possible -
Cryptosporidium parvum
Length = 1001
Score = 79.4 bits (187), Expect = 1e-13
Identities = 66/232 (28%), Positives = 108/232 (46%), Gaps = 27/232 (11%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
YH NP+HN HA ++ ++ +L + S+R ++ +E ++S+++HD+ HPG+ +
Sbjct: 717 YHEENPFHNFHHAVSISITLNNWLDKPSVRHYVNSLEAYCLIISSLSHDLDHPGLTND-M 775
Query: 228 IATCNHLA-----------DLYRILEGTS-------ENFSVLESHHWRAALSCIIESGLL 353
I N L+ + IL+ + NFSVLE+HH + L I+
Sbjct: 776 IKELNILSRKVLQEFTTDEQFFEILQNNTLSTLKIYNNFSVLENHH-SSLLFVILNDEAS 834
Query: 354 EERP----DLQEELKKHLKVLIMATDITRQHDYLS----RFKKLLDTNTLDMRIQ-EHRI 506
P EL K + I+ TD+ QH YL F K +N+ + ++ + +
Sbjct: 835 NIMPPTTSKYYSELHKMMINSILFTDMF-QHKYLRDLVLNFNKNYSSNSRSIEVEAQKKK 893
Query: 507 LVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCD 662
L L I L DISNP ++ KWS V EE Q + ML++ + D
Sbjct: 894 LYLLILLHSVDISNPLMNTNIYLKWSRLVYEELENQKKLKLMLNISLNDTTD 945
>UniRef50_A3FPW6 Cluster: Phosphdiesterase, putative; n=1;
Cryptosporidium parvum Iowa II|Rep: Phosphdiesterase,
putative - Cryptosporidium parvum Iowa II
Length = 1206
Score = 79.4 bits (187), Expect = 1e-13
Identities = 66/232 (28%), Positives = 108/232 (46%), Gaps = 27/232 (11%)
Frame = +3
Query: 48 YHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
YH NP+HN HA ++ ++ +L + S+R ++ +E ++S+++HD+ HPG+ +
Sbjct: 922 YHEENPFHNFHHAVSISITLNNWLDKPSVRHYVNSLEAYCLIISSLSHDLDHPGLTND-M 980
Query: 228 IATCNHLA-----------DLYRILEGTS-------ENFSVLESHHWRAALSCIIESGLL 353
I N L+ + IL+ + NFSVLE+HH + L I+
Sbjct: 981 IKELNILSRKVLQEFTTDEQFFEILQNNTLSTLKIYNNFSVLENHH-SSLLFVILNDEAS 1039
Query: 354 EERP----DLQEELKKHLKVLIMATDITRQHDYLS----RFKKLLDTNTLDMRIQ-EHRI 506
P EL K + I+ TD+ QH YL F K +N+ + ++ + +
Sbjct: 1040 NIMPPTTSKYYSELHKMMINSILFTDMF-QHKYLRDLVLNFNKNYSSNSRSIEVEAQKKK 1098
Query: 507 LVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCD 662
L L I L DISNP ++ KWS V EE Q + ML++ + D
Sbjct: 1099 LYLLILLHSVDISNPLMNTNIYLKWSRLVYEELENQKKLKLMLNISLNDTTD 1150
>UniRef50_A2E0V4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Trichomonas vaginalis G3
Length = 438
Score = 79.4 bits (187), Expect = 1e-13
Identities = 56/177 (31%), Positives = 88/177 (49%), Gaps = 4/177 (2%)
Frame = +3
Query: 63 PYHNSIHATDVTQAM-HCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
PYHN HA DVTQ + + ++ G + F + E +++AI D H G + I
Sbjct: 211 PYHNWRHAVDVTQFVTYQIMISGHEKVFTK-FEF-NLVVAAICRDANHDGFTNIYNIKAE 268
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEE-RPDLQEELKKHLKVLIM 410
L LY+ N SV+E+HH A+ + E+ LL D E+ + I+
Sbjct: 269 TPLGILYK-------NQSVMETHHCSIAIQIMSHEETNLLATLNQDECNEIWSLIIQYIL 321
Query: 411 ATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
ATD+ R + L RF + D + + +HR+++L + LKC DISN RP+ + +W
Sbjct: 322 ATDMARHFEILKRFIDIYDDSDFTTQRHDHRVMLLYMILKCGDISNVSRPFELVDRW 378
>UniRef50_A6R1R4 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 839
Score = 79.0 bits (186), Expect = 1e-13
Identities = 57/163 (34%), Positives = 88/163 (53%), Gaps = 8/163 (4%)
Frame = +3
Query: 177 SAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLE 356
SAI HD+ HPGVN FL+ LA LY + SVLES H AA S ++ S
Sbjct: 295 SAIGHDVGHPGVNNVFLVRLNAPLAQLYN-------DTSVLESFHC-AAYSQLLRSYWPS 346
Query: 357 ERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLD----TNTLDM----RIQEHRILV 512
D++ L+K + I+ATD+ ++ KL + T++ D I+ +R L+
Sbjct: 347 FVMDMK--LRKLMISSILATDMGVHFKFMESLGKLREKYHETHSTDRWTDNEIETNRALL 404
Query: 513 LQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDL 641
+ +KCADISN R W ++++W+ + EEF +QG+ EK + +
Sbjct: 405 CGLLMKCADISNVARTWDIAKRWTNVLQEEFAQQGNMEKTIGM 447
>UniRef50_Q6CHK1 Cluster: Similar to tr|Q8NJP9 Candida albicans High
affinity cAMP phosphodiesterase; n=1; Yarrowia
lipolytica|Rep: Similar to tr|Q8NJP9 Candida albicans
High affinity cAMP phosphodiesterase - Yarrowia
lipolytica (Candida lipolytica)
Length = 626
Score = 78.6 bits (185), Expect = 2e-13
Identities = 69/232 (29%), Positives = 107/232 (46%), Gaps = 30/232 (12%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQ-GSIR------------------AF 143
+ + YH NPYHN HA DV QA FL++ G + A
Sbjct: 344 RFLIMMRDAYHHENPYHNFRHAIDVMQATFQFLIRLGCLPPPPFKRAPNCSMIPPIGPAV 403
Query: 144 IRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAA 323
P E + +++AI HDI HPGV FL+++ + +A ++ + SVLES+H
Sbjct: 404 FTPAESLVVIIAAIGHDISHPGVTNAFLVSSHSPMAQVF-------NDKSVLESYH---- 452
Query: 324 LSCIIESGLLEERPDLQE-ELKKHLKVLIMATDITRQHDYLSRFKKLLD--TNTLDMRIQ 494
+C++ L P QE LKK + ++ATD+ + +Y+ R+ +L + R
Sbjct: 453 -ACVLNRVLNIFWPATQEPHLKKLIVESVLATDMAQHFNYVDRWNELSARCRSKGKGRCN 511
Query: 495 EH--------RILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYE 626
E R LV + +KCAD+SN R +++KW + EF D E
Sbjct: 512 EERGNLSPADRQLVGSMIMKCADVSNVTRRLDLAEKWGRVLQCEFSEVKDVE 563
>UniRef50_UPI0000E46CDB Cluster: PREDICTED: similar to
phosphodiesterase 9A; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to phosphodiesterase
9A - Strongylocentrotus purpuratus
Length = 526
Score = 77.8 bits (183), Expect = 3e-13
Identities = 48/173 (27%), Positives = 87/173 (50%), Gaps = 3/173 (1%)
Frame = +3
Query: 168 CLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES- 344
C + + PG N + + LA Y + S LE+HH A + +
Sbjct: 229 CFCVSQMFSLDRPGYNNAYHVNAGTELALRYN-------DISPLENHHCSVAFKILEKPH 281
Query: 345 -GLLEE-RPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQ 518
+ + P++ +++++ + I+ATD+ + ++ L+ FK ++ +T D + H+ L+ +
Sbjct: 282 CNIFKNLSPEIFKQVREGIIRCILATDMAKHNEILNGFKDII--STFDFSNKVHKDLLTK 339
Query: 519 IALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
I +K ADISN RP V++ W + +EFF Q D EK+ LPV DR+ +
Sbjct: 340 ICIKVADISNEARPMDVAEPWIDCLLQEFFNQSDMEKLEGLPVAPFMDREKVT 392
>UniRef50_Q3UEI1-2 Cluster: Isoform 2 of Q3UEI1 ; n=1; Mus
musculus|Rep: Isoform 2 of Q3UEI1 - Mus musculus (Mouse)
Length = 652
Score = 77.8 bits (183), Expect = 3e-13
Identities = 48/152 (31%), Positives = 78/152 (51%), Gaps = 3/152 (1%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YHS YHNS+HA DV Q+ H L ++ A +E++A + + HD+ H
Sbjct: 375 LLTL-EGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDH 433
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI--IESGLLEERPDLQE 377
PGV+ FLI T + LA +Y + SVLE+HH + + Q
Sbjct: 434 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQR 486
Query: 378 -ELKKHLKVLIMATDITRQHDYLSRFKKLLDT 470
L++ + +++ATD+++ L+ K +++T
Sbjct: 487 LSLRRMVIDMVLATDMSKHMSLLADLKTMVET 518
>UniRef50_Q7Q8G2 Cluster: ENSANGP00000013023; n=2; Diptera|Rep:
ENSANGP00000013023 - Anopheles gambiae str. PEST
Length = 747
Score = 77.4 bits (182), Expect = 4e-13
Identities = 55/202 (27%), Positives = 93/202 (46%), Gaps = 5/202 (2%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +VTQ M L +E +A +++ + HD+ H G N F I +
Sbjct: 496 YHNWRHAFNVTQMMFAILTSTQWWKIFGEIECLALIIACLCHDLDHRGTNNSFQIKASSP 555
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVL---IMAT 416
LA LY + S +E HH+ L I G E+ + ++VL I++T
Sbjct: 556 LAQLY--------STSTMEHHHFDQCLMIINSPGNQILSNMSSEDYSRVIRVLEDAILST 607
Query: 417 DITRQHDYLSRFKKLLD--TNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVK 590
D+ F L++ + + +E R L+ +++ D+S +PW + ++ +
Sbjct: 608 DLAVYFRKRGAFLNLVEPASEMSSWQAEEPRSLLRAMSMTVCDLSAITKPWEIEKRVADL 667
Query: 591 VCEEFFRQGDYEKMLDLPVTQL 656
V EFF QGD E+ +L +T +
Sbjct: 668 VSSEFFEQGDMERQ-ELNITPI 688
>UniRef50_Q53I59 Cluster: Cyclic nucleotide specific
phosphodiesterase; n=3; Trypanosoma cruzi|Rep: Cyclic
nucleotide specific phosphodiesterase - Trypanosoma
cruzi
Length = 924
Score = 77.4 bits (182), Expect = 4e-13
Identities = 60/218 (27%), Positives = 97/218 (44%), Gaps = 1/218 (0%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGS-IRAFIRPVEIIACLLSAIAHDIF 200
L E+ Y NPYHN+IHA DV Q + + + P+E A +A+ HD+
Sbjct: 354 LVAAVENNYRP-NPYHNAIHAADVLQGTFSLVSAAKPLMEHLTPLECKAAAFAALTHDVC 412
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE 380
HPG FL A + ++ + +GT E + + S + + L E
Sbjct: 413 HPGRTNAFLAAVQDPVSFKFSG-KGTLEQLHTVTAFELLNVTEFDFTSSM-DNASFL--E 468
Query: 381 LKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRP 560
K + LI TD++ + +++ L D +E R+ L + L ADI R
Sbjct: 469 FKNIVSHLIGHTDMSLHSETIAKHGAKLSAGGFDCTCKEDRLEALSLLLHAADIGASSRG 528
Query: 561 WSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDST 674
++++KW V + +EF Q + E+ LPVT D S+
Sbjct: 529 VAIARKWLV-ILQEFADQAEDERRRGLPVTPGFDTPSS 565
>UniRef50_A2FQB0 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1042
Score = 77.4 bits (182), Expect = 4e-13
Identities = 54/200 (27%), Positives = 90/200 (45%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA DV Q + L + + P+EI A ++AI HD H G + F
Sbjct: 799 PYHNWRHACDVVQFVSFVLQSINAKEIFEPIEISAIFIAAICHDAGHDGYSNIFNRQAST 858
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVLIMATDI 422
L +Y + +N E H + ++ ++ S ++ +++ I
Sbjct: 859 PLGQIY-----SGKNCE--ELFHL-SLIARVVNSPECNIFSNMTHATMAKFWAMMIRMII 910
Query: 423 TRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEE 602
+ S+ N LDM+ Q RI VL + L ++ISN RP+ V+ +W + E
Sbjct: 911 DTDLEVFSQVMSNNSLNNLDMKNQNSRIKVLSLILILSNISNVARPFDVAMRWLDCLSTE 970
Query: 603 FFRQGDYEKMLDLPVTQLCD 662
+++QGD EK L + T + +
Sbjct: 971 YYKQGDIEKSLGMKYTNVAN 990
>UniRef50_Q1DXU2 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 900
Score = 76.2 bits (179), Expect = 1e-12
Identities = 69/221 (31%), Positives = 106/221 (47%), Gaps = 26/221 (11%)
Frame = +3
Query: 42 SGYHSTNPYHNSIHATDVTQAMHCFLLQ---------GS--------IRAFIRPVEIIAC 170
+ Y+S YHN HA DV Q++ FL++ GS + + + P + +
Sbjct: 356 ASYNSFVLYHNFRHAIDVLQSVFHFLVKIGILPPFPLGSEEVSTRSGMSSILTPFDALTL 415
Query: 171 LLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL 350
L++AI HD+ HPGVN FL+ LA LY + SVLE+ H AA S I+
Sbjct: 416 LITAIGHDVGHPGVNNVFLVKLNAPLAQLYN-------DKSVLEAFHC-AAYSQILRRHW 467
Query: 351 LEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMR---------IQEHR 503
D L+K + I+ATD+ + ++ KL + + R I +R
Sbjct: 468 PSVFKD--NRLRKLMIDSILATDMGIHNVFMESLGKLQQSYRSNNRTTWGWEPKDIDTYR 525
Query: 504 ILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYE 626
L+ + +KCADISN RP+ +++KW+ + EF QG E
Sbjct: 526 TLLCALLIKCADISNVARPFHIAEKWTDILQLEFANQGMME 566
>UniRef50_P06776 Cluster: 3',5'-cyclic-nucleotide phosphodiesterase
2; n=2; Saccharomyces cerevisiae|Rep:
3',5'-cyclic-nucleotide phosphodiesterase 2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 526
Score = 74.9 bits (176), Expect = 2e-12
Identities = 64/200 (32%), Positives = 97/200 (48%), Gaps = 6/200 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQA---MHCFLLQGSIRAFIRPVEIIACLLSAIAHD 194
LFTL ES YH N +HN HA DV QA + +LL+ + PV+ + ++AI HD
Sbjct: 251 LFTL-ESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDN------PVQTLLLCMAAIGHD 303
Query: 195 IFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQ 374
+ HPG N L CN +++ + +N S+LE+ H + + L E P L
Sbjct: 304 VGHPGTNNQLL---CNCESEVAQ----NFKNVSILENFHRE-----LFQQLLSEHWPQLL 351
Query: 375 EELKKHLKVL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADIS 545
KK + I+ATD+ Y R L+ N + +I ++ + +K ADIS
Sbjct: 352 SISKKKFDFISEAILATDMALHSQYEDR---LMHENPM------KQITLISLIIKAADIS 402
Query: 546 NPCRPWSVSQKWSVKVCEEF 605
N R S+S +W+ + EF
Sbjct: 403 NVTRTLSISARWAYLITLEF 422
>UniRef50_A0D3N1 Cluster: Chromosome undetermined scaffold_36, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_36,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 429
Score = 74.5 bits (175), Expect = 3e-12
Identities = 65/237 (27%), Positives = 104/237 (43%), Gaps = 22/237 (9%)
Frame = +3
Query: 12 NAGKLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAH 191
N L T Y+ + YHN HA + Q + C + ++ F+ +I A LL++++H
Sbjct: 144 NLENLLTHINLNYNIVS-YHNFTHAFALFQLLFCVYEKSDLKLFVSKQDIFAALLASLSH 202
Query: 192 DIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES---GLLEER 362
DI H GVN + + L I E +VLES H + + ++ L
Sbjct: 203 DINHKGVNNLYKVKKSKKLNK--NICEQ-----AVLESMHVSTLFNILAQNQQLNFLNYL 255
Query: 363 PDL-QEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQ--------------- 494
P+ Q+E K+ L I+ATD+ + + S FK ++ T+++R
Sbjct: 256 PNAQQQEFKRILVSSILATDMGQHFNIFSCFKDRVNA-TIELRESQDITDPLIRYRGFNK 314
Query: 495 ---EHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQL 656
+ R +L + + DISNPC W KWS + +EF Q E L VT +
Sbjct: 315 ENFDDRKFILNVLVHACDISNPCLEWDAYMKWSFLLAQEFQDQTIKEAAKGLEVTAM 371
>UniRef50_P16499 Cluster: Rod cGMP-specific 3',5'-cyclic
phosphodiesterase subunit alpha; n=90; Vertebrata|Rep:
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit
alpha - Homo sapiens (Human)
Length = 860
Score = 74.1 bits (174), Expect = 4e-12
Identities = 56/208 (26%), Positives = 96/208 (46%), Gaps = 13/208 (6%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY YHN H +V Q M L+ G ++ + +E +A + +A HDI H G N +
Sbjct: 552 GYRKIT-YHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLY 610
Query: 225 LIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL--LEERPDLQEELKKH-L 395
+ + N LA L+ S+LE HH + + + L + Q E H +
Sbjct: 611 QMKSQNPLAKLH--------GSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMM 662
Query: 396 KVLIMATDITRQHDYLSRFKKLLD-TNTLD---------MRIQEHRILVLQIALKCADIS 545
+ I+ATD+ + F+K++D + T + M Q + +V+ + + D+S
Sbjct: 663 DIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWTQYMMLEQTRKEIVMAMMMTACDLS 722
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEK 629
+PW V + ++ V EF+ QGD E+
Sbjct: 723 AITKPWEVQSQVALLVAAEFWEQGDLER 750
>UniRef50_UPI0001554EBF Cluster: PREDICTED: similar to cyclic
nucleotide phophodiesterase, partial; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
cyclic nucleotide phophodiesterase, partial -
Ornithorhynchus anatinus
Length = 340
Score = 73.7 bits (173), Expect = 5e-12
Identities = 51/170 (30%), Positives = 87/170 (51%), Gaps = 7/170 (4%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 178 GCLASNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYN-------DRSVLEN 230
Query: 306 HHWRAALSCII---ESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFK-KLLDT 470
HH +A + + E L ++ + + L + I+ATD+ + D+L+ F K D
Sbjct: 231 HHAASAWNLFLSRPEYNFLSNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDV 290
Query: 471 NT--LDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQ 614
N+ ++ + R+LV Q+ +K ADI+ P + + KW+ + EF+ Q
Sbjct: 291 NSSGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQ 340
Score = 33.5 bits (73), Expect = 6.9
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E+GY PYHN IHATDV A+
Sbjct: 25 FRALENGYRDI-PYHNRIHATDVLHAV 50
>UniRef50_A0E2C5 Cluster: Chromosome undetermined scaffold_74, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_74, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 975
Score = 73.7 bits (173), Expect = 5e-12
Identities = 58/203 (28%), Positives = 96/203 (47%), Gaps = 8/203 (3%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQ---GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
N +HN H V Q +H LLQ S A I A LLS + HD+ H G F I
Sbjct: 721 NVFHNYDHGVSVMQNVHAILLQLHQTSNAAIISTFNQFALLLSGLCHDVSHTGRTNTFEI 780
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALS--CIIESGLLEERPDLQEELKKHLKVL 404
+ ++LA Y + SVLE HH +L C+ + +L+ EE +K ++
Sbjct: 781 NSLSNLAIRY-------HDRSVLEQHHAAKSLKLLCVPATNILQSFKG--EEFRKFRRMF 831
Query: 405 ---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQ 575
I+ TDIT + + F+ + + + ++ ++L I + +D + + + +S+
Sbjct: 832 ISNILYTDITEHFNLIKNFESKVSESNFGQQDEDIKLLSGMI-IHTSDFTGGAKQFELSK 890
Query: 576 KWSVKVCEEFFRQGDYEKMLDLP 644
+WS KV +EF +Q + E L P
Sbjct: 891 QWSFKVNKEFEQQYELEGKLGYP 913
>UniRef50_Q9VJ79 Cluster: Dual 3',5'-cyclic-AMP and -GMP
phosphodiesterase 11; n=9; Eumetazoa|Rep: Dual
3',5'-cyclic-AMP and -GMP phosphodiesterase 11 -
Drosophila melanogaster (Fruit fly)
Length = 1451
Score = 73.7 bits (173), Expect = 5e-12
Identities = 54/200 (27%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L +E +A ++ + HD+ H G N F I +
Sbjct: 859 YHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSP 918
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY + S +E HH+ L + G L D + + L+ I++T
Sbjct: 919 LAQLY--------STSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILST 970
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+ F + + T +E R L+ +++ D+S +PW + ++ + V
Sbjct: 971 DLAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVS 1030
Query: 597 EEFFRQGDYEKMLDLPVTQL 656
EFF QGD EK +L +T +
Sbjct: 1031 SEFFEQGDMEKQ-ELNITPI 1049
>UniRef50_Q4FXD4 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major strain Friedlin
Length = 1084
Score = 72.9 bits (171), Expect = 9e-12
Identities = 61/219 (27%), Positives = 97/219 (44%), Gaps = 2/219 (0%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQ-GSIRAFIRPVEIIACLLSAIAHDIF 200
L ++ Y + N YHN +HA DV Q ++ + + + VE A + +A HDI
Sbjct: 598 LLATVQANYRA-NQYHNRVHAADVLQGVYAMICSCPGLLPHMTTVEKRAVVFAAAVHDIR 656
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE 380
HPG ++ FL T + Y L+ E + H A G +++ L E
Sbjct: 657 HPGRSEVFLKNTFDATYVHYNGLQ-VLEQMHTATAFHLLATPELDFTRGNMDDTEAL--E 713
Query: 381 LKKHLKVLIMATDITRQHDYLSRFKK-LLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
+ LI T + R + ++ + L D T DM + R VL + L ADI R
Sbjct: 714 FHGLVAALIGCTFMGRHASLMEQWSRPLQDGKTYDMAVTADRQQVLSLFLHAADIGAQAR 773
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDST 674
+V++KW + + EE QGD E LP++ R ++
Sbjct: 774 GLTVARKW-LGIVEEMRAQGDDEAARGLPLSPGSSRSAS 811
>UniRef50_Q7RXW7 Cluster: Putative uncharacterized protein
NCU00478.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU00478.1 - Neurospora crassa
Length = 806
Score = 72.9 bits (171), Expect = 9e-12
Identities = 71/225 (31%), Positives = 98/225 (43%), Gaps = 30/225 (13%)
Frame = +3
Query: 42 SGYHSTNPYHNSIHATDVTQAMHCFLLQ-GSIRAF-------------------IRPVEI 161
+ Y PYHN H DV QA LL+ G++ + I P E
Sbjct: 297 AAYMGFVPYHNFRHVVDVLQATFQQLLRIGALPPYPNVNGTHTSPIAESPGTPSIGPEEA 356
Query: 162 IACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIE 341
LL+AI HD+ HPGVN GFLI LA+LY + SVLE+ H + C I
Sbjct: 357 FTLLLTAIGHDVLHPGVNNGFLIEARAPLAELY-------NDRSVLENFH--STSYCQI- 406
Query: 342 SGLLEERPDLQE--ELKKHLKVLIMATDITRQHDYLSRFKKL--LDTNTLDM------RI 491
L P E L+ + I+ATD+ DY+++ L L D+ +
Sbjct: 407 --LKRHWPIFYENRRLRTLMISCILATDMALHFDYMAKLGNLQKLQAQKPDLDGWNEKAV 464
Query: 492 QEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYE 626
E R+LV + +KCADISN R + +W + +E Q E
Sbjct: 465 DEARVLVCALIIKCADISNVARRHDIGAQWMHLLNDELILQTQIE 509
>UniRef50_Q4SPD6 Cluster: Chromosome 16 SCAF14537, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 16 SCAF14537, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 560
Score = 72.5 bits (170), Expect = 1e-11
Identities = 37/94 (39%), Positives = 51/94 (54%)
Frame = +3
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + L FK+ +D D +EH + + +KC DISN RP V++ W
Sbjct: 414 LILATDMARHGEILDSFKQKVDN--FDFTNEEHVTCLKMVLIKCCDISNEVRPTEVAEPW 471
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+ EE+F Q D EK LPV DRD + P
Sbjct: 472 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKP 505
>UniRef50_Q6FM93 Cluster: Similar to sp|P06776 Saccharomyces
cerevisiae YOR360c PDE2 high affinity 3; n=1; Candida
glabrata|Rep: Similar to sp|P06776 Saccharomyces
cerevisiae YOR360c PDE2 high affinity 3 - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 575
Score = 71.7 bits (168), Expect = 2e-11
Identities = 66/224 (29%), Positives = 103/224 (45%), Gaps = 30/224 (13%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMH--CFLLQGSIRAFIRPVEIIACLLSAIAHDI 197
L E+ YH N +HN HA DV QA C L G+ + P+ ++ +SAI HDI
Sbjct: 239 LLITIEASYHQINKFHNFRHAVDVMQATWQICSNLGGNGSIDLSPLTVLLLSMSAIGHDI 298
Query: 198 FHPGVNQGFLIATCNHLA---DLYRILEGTSEN-FSVLESHHW----RAALSCIIESG-- 347
HPG N L + LA D +LE F L HW +AA ++SG
Sbjct: 299 GHPGTNNQLLCQHESFLATNFDNKSVLENFHNTLFQNLLVDHWPQILKAARYKTVQSGEI 358
Query: 348 --------LLEERPDLQE----ELKKHLKVL---IMATDITRQHDYLSRFKKLLDTNTLD 482
L++ ++ E + K + V+ I+ATD+ Y+ + +LL
Sbjct: 359 NVTDIPFVNLKKSNNINENDDNDKKMTINVITNAILATDMAMHAKYVDKLDELL------ 412
Query: 483 MRIQEHRI---LVLQIALKCADISNPCRPWSVSQKWSVKVCEEF 605
++ +H + ++ + +K ADISN RP S+S +W+ + EF
Sbjct: 413 -KVPQHLLPLPTLIAVIIKAADISNVTRPLSISARWAFLITLEF 455
>UniRef50_Q9Y233 Cluster: cAMP and cAMP-inhibited cGMP 3',5'-cyclic
phosphodiesterase 10A; n=44; Euteleostomi|Rep: cAMP and
cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A -
Homo sapiens (Human)
Length = 779
Score = 71.3 bits (167), Expect = 3e-11
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 513 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 570
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 571 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 622
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 623 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 682
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 683 YAEFWAEGDEMKKLGIQPIPMMDRD 707
>UniRef50_A5DVX9 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 638
Score = 70.9 bits (166), Expect = 4e-11
Identities = 52/178 (29%), Positives = 85/178 (47%), Gaps = 5/178 (2%)
Frame = +3
Query: 117 LLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSV 296
L QG + I PV+ +A L+SA+ HD+ HPG FL+ ++ +Y + SV
Sbjct: 366 LNQGGLGCVINPVQSLALLMSALGHDVGHPGTTNAFLMQNKAPISLIY-------NDRSV 418
Query: 297 LESHHWRAALSCIIE---SGLLEERPDLQEELKKH--LKVLIMATDITRQHDYLSRFKKL 461
LES+H ++ I+ LL + + +L H + I+ATD++ +YL + L
Sbjct: 419 LESYHAAVYINQILVVFWPSLLTTKIAEESKLLIHDVVSATILATDMSNHFEYLHQVDSL 478
Query: 462 LDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKML 635
L+ + LK ADISN RP +S +W+V + EF E+++
Sbjct: 479 SKEEDYGPCSDRKIKLLGSLLLKAADISNVARPLKISCQWAVVLQREFDEIKQLEELI 536
>UniRef50_UPI0000660DD6 Cluster: Homolog of Homo sapiens
"Phosphodiesterase PDE9A5; n=1; Takifugu rubripes|Rep:
Homolog of Homo sapiens "Phosphodiesterase PDE9A5 -
Takifugu rubripes
Length = 305
Score = 70.1 bits (164), Expect = 6e-11
Identities = 35/94 (37%), Positives = 51/94 (54%)
Frame = +3
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + L FK+ +D D ++H + + +KC DISN RP V++ W
Sbjct: 5 LILATDMARHGEILDSFKQKVDG--FDFADEDHMTCLKMVLIKCCDISNEVRPMEVAEPW 62
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+ EE+F Q D EK LPV DR+ + P
Sbjct: 63 VDCLLEEYFMQSDREKTEGLPVAPFMDREKVTKP 96
>UniRef50_Q758Y3 Cluster: ADR395Cp; n=1; Eremothecium gossypii|Rep:
ADR395Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 480
Score = 69.7 bits (163), Expect = 9e-11
Identities = 59/192 (30%), Positives = 92/192 (47%), Gaps = 3/192 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMH--CFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
E YH N + N HA DV QA + C LL+ + P + +SAI HD+ HPG
Sbjct: 226 ECSYHQGNKFPNFRHAVDVMQATYQLCDLLK------LDPGISLTLCISAIGHDVAHPGT 279
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKH 392
N + C + + + + G S VLE+ H S + S L + P+ + +++
Sbjct: 280 NNALM---CKYGSPVAKHYNGVS----VLENFH-----SDVFISILGQHWPEFSDVVQRQ 327
Query: 393 -LKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I++TD+ YL KL T +R E L+ + +K ADISN RP +
Sbjct: 328 AIRDAIISTDMALHEQYLL---KLRSCGTRSLR--EDIPLLTSLIIKAADISNVSRPLII 382
Query: 570 SQKWSVKVCEEF 605
S +W+V + EF
Sbjct: 383 SAQWAVLISYEF 394
>UniRef50_Q6BSL2 Cluster: Similar to tr|O94034 Candida albicans
Nucleotide phosphodiesterase; n=2;
Saccharomycetaceae|Rep: Similar to tr|O94034 Candida
albicans Nucleotide phosphodiesterase - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 611
Score = 69.3 bits (162), Expect = 1e-10
Identities = 52/172 (30%), Positives = 87/172 (50%), Gaps = 6/172 (3%)
Frame = +3
Query: 138 AFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWR 317
A + ++ +A L++A+ HD+ HPGV F+I H A + I S VLE +H
Sbjct: 377 AHMNSIQTLALLIAALGHDVGHPGVTNAFMI---KHSAPMSLIYNERS----VLELYHSA 429
Query: 318 AALSCIIE---SGLLEERPDLQEELK-KHLKV-LIMATDITRQHDYLSRFKKLLDTNTLD 482
++ I+ G+L D + ++ K+L + I+ATD+ +Y+ KL
Sbjct: 430 VFINKILAINWPGILSVNIDRKTKISLKNLIISCILATDMAEHFEYID---KLAHFKADR 486
Query: 483 MRIQEHRI-LVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKML 635
++ +R+ L+ + +KCADISN RP VS +W++ + EF EK L
Sbjct: 487 YMLEVNRVNLISSLLIKCADISNVTRPLRVSSQWALVLGREFCEVSTLEKKL 538
>UniRef50_UPI0001555C30 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein, partial - Ornithorhynchus anatinus
Length = 319
Score = 68.9 bits (161), Expect = 2e-10
Identities = 38/104 (36%), Positives = 60/104 (57%)
Frame = +3
Query: 369 LQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISN 548
++ EL+ + ++++TD++ + K L L+ RI + + L + L ADIS+
Sbjct: 75 VERELRSLVIEMVLSTDMSCHFQQVKSMKTSLQQ--LE-RIDKSK--ALSLLLHAADISH 129
Query: 549 PCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
P + WSV +W+ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 130 PTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLV 173
>UniRef50_A7SW30 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 600
Score = 68.9 bits (161), Expect = 2e-10
Identities = 51/213 (23%), Positives = 90/213 (42%), Gaps = 4/213 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V ++ + + E ++ ++ I HD+ H G N F++
Sbjct: 368 PYHNWCHAFSVAHSLWIVIRDNKS---LTDYEKLSLFIAGICHDVDHRGKNNAFMLHCKT 424
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVL---IMA 413
LA+LY S +E HH++ + + G E ++ L+++ I+A
Sbjct: 425 PLANLYTT--------STMEWHHFKQGVFILESEGQNVFGQLDAESYRRVLELIQEAIIA 476
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + L + ++HR L+ + + D+ +PW + KV
Sbjct: 477 TDLMLFFGNKKELETLQENKAFRWEEEKHRSLIRCLLMTACDLCTSAKPWDIQVVAVNKV 536
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRDS-TSIPXN 689
EEF+ QGD E+ + L + DR +P N
Sbjct: 537 FEEFYIQGDEERKMGLDPLPMMDRSKHDDLPEN 569
>UniRef50_Q4RG61 Cluster: Chromosome 2 SCAF15106, whole genome shotgun
sequence; n=3; Tetraodontidae|Rep: Chromosome 2
SCAF15106, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 899
Score = 68.1 bits (159), Expect = 3e-10
Identities = 65/227 (28%), Positives = 105/227 (46%), Gaps = 19/227 (8%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY + YHN H +V M C L G +R + ++ A + +A HDI H G N +
Sbjct: 600 GYRAIT-YHNWRHGFNVGHTMFCLLQTGRLRKYYSDLDAFAMVAAAFCHDIDHRGTNNLY 658
Query: 225 LIATCNH-LADLYRILEGTSENFSVLESHHWRAALSCIIESGL-----LEERPDLQEELK 386
H LA L+ GT S++E HH + + + E L L++R Q E
Sbjct: 659 QTKRSAHPLAKLH----GT----SIMERHHLEYSKTLMAEETLNIFCNLQKR---QFEHV 707
Query: 387 KHL-KVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRI-----------LVLQIALK 530
+HL V I+ATD+ + F+ +++ T M ++ I +V+ + +
Sbjct: 708 QHLFDVCIIATDLALYFKKRTMFQNIVNA-TEPMADEKEAIGYVSNNPIRKEIVMAMMMT 766
Query: 531 CADISNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRD 668
D+S +PW V K ++ V EF+ QGD E+ +LD + DR+
Sbjct: 767 GCDLSAITKPWEVQSKVALMVAAEFWEQGDLERNVLDQQPIPMMDRN 813
>UniRef50_A2E4B2 Cluster: Response regulator receiver domain
containing protein; n=1; Trichomonas vaginalis G3|Rep:
Response regulator receiver domain containing protein -
Trichomonas vaginalis G3
Length = 637
Score = 68.1 bits (159), Expect = 3e-10
Identities = 51/202 (25%), Positives = 86/202 (42%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
NP+HN + ++ + + P E A L +A+ HDI HPG N F I T
Sbjct: 323 NPFHN--FRRSIAGLQFATMILSKYKERVPPFEAAAGLFAALLHDIGHPGTNNMFQIRTS 380
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVLIMATD 419
+ LA +Y + SVLE + + E L+ ++ATD
Sbjct: 381 SQLALIYN-------DKSVLEMNSASVGARLVQEVFSFSIDDQDFSTLRATFLSNVLATD 433
Query: 420 ITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCE 599
++ +L++ + +D +EHR + LQ+ +D+S R W + W + +
Sbjct: 434 YSKLQKFLAKAANI----KMDWENKEHRQIALQLLTLMSDLSFAIRNWKTTSYWYGMMRD 489
Query: 600 EFFRQGDYEKMLDLPVTQLCDR 665
E + QGD E+ ++ L DR
Sbjct: 490 EHYIQGDMERKRNMKSIPLMDR 511
>UniRef50_Q57ZK5 Cluster: 3', 5'-cyclic nucleotide
phosphodiesterase, putative; n=1; Trypanosoma
brucei|Rep: 3', 5'-cyclic nucleotide phosphodiesterase,
putative - Trypanosoma brucei
Length = 909
Score = 67.7 bits (158), Expect = 3e-10
Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 7/211 (3%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEII---ACLLSAIAHDIFHPG 209
E+ Y NP+HN++ A DV QA+ F L + + +R V ++ A + +A+A D+ HPG
Sbjct: 357 ENNYRP-NPFHNAVRAADVVQAV--FSLASATKPLMRHVTLVELKALVFAAVALDVRHPG 413
Query: 210 VNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE--- 380
FL+ TC+ L Y LE H A ++E L + +E
Sbjct: 414 RTNEFLVRTCDPLCYRY-------PGPGTLEQMHVATAFQ-LVEVPELNFTCRMNDESFL 465
Query: 381 -LKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
K + LI TD D+L ++ D + R+ L + L AD R
Sbjct: 466 RFKTIVSKLICRTDTAVLEDHLEHWRAKAREGGFDYGAPDDRVDALSLLLLAADFGVISR 525
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
++ KW V + EE Q E+ LPVT
Sbjct: 526 GADIAAKWLV-LTEEHAAQAQEERRRGLPVT 555
>UniRef50_A7TPP3 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 518
Score = 67.7 bits (158), Expect = 3e-10
Identities = 61/197 (30%), Positives = 96/197 (48%), Gaps = 3/197 (1%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
LF+L E+ YH N +HN HA DV QA + L + +++ C ++AI HDI H
Sbjct: 252 LFSL-EASYHQVNKFHNFRHAVDVMQATY-QLCDKLLTKDDHIYKLLLC-MAAIGHDIAH 308
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQE 377
PG N L+ + +A + +N SVLE+ H + + L++ ++
Sbjct: 309 PGTNNNLLVNYKSSVALHF-------DNESVLENFHQVLFQQLLFDQWPSLIDIVTQCEK 361
Query: 378 ELKKH-LKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPC 554
K + +K I+ATD+ SR+ K L+ D RI ++ +K ADISN
Sbjct: 362 RDKFNIIKDSILATDMAIH----SRYVKQLNPEE-DFRINN----LISFIIKAADISNVT 412
Query: 555 RPWSVSQKWSVKVCEEF 605
RP VS +W++ + EF
Sbjct: 413 RPLHVSAQWALLISLEF 429
>UniRef50_A4VDP2 Cluster: Cyclic nucleotide phosphodiesterase; n=1;
Tetrahymena thermophila SB210|Rep: Cyclic nucleotide
phosphodiesterase - Tetrahymena thermophila SB210
Length = 1074
Score = 67.3 bits (157), Expect = 5e-10
Identities = 67/279 (24%), Positives = 127/279 (45%), Gaps = 11/279 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMH-CFLL--QGSIRAFIRPVEIIACLLSAIAHD 194
L+ L E NP+HN H V MH CF++ + + ++ ++ + + S + HD
Sbjct: 770 LYKLREKYNKRENPFHNFDHGIMV---MHGCFMIGCRTNANKYLNSIQEFSLVFSGLCHD 826
Query: 195 IFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL-LEERPDL 371
+ H G F + T + LA Y + SVLE HH + +S + + +
Sbjct: 827 VSHRGKTNAFEVNTMSKLAIRY-------HDQSVLEQHHIAHTFKILRQSNANIFKNLTI 879
Query: 372 Q--EELKKHLKVLIMATDITRQHDYLSRFKK--LLDTNTLDM-RIQEHRI-LVLQIALKC 533
Q +++++++ I+ATD+++ DYL F+ L + + + + +E I L+ +
Sbjct: 880 QKVQQIRRYVINNILATDMSKHFDYLKDFQNDFLQEVHKKESNQFEEKEINLLTGTIIHT 939
Query: 534 ADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIPXNTNXLL*I 710
+D + + + +S++WSVKV +EF +Q E + T L D D +
Sbjct: 940 SDFHHTAQKFELSKQWSVKVNKEFSQQYIEEGKQGVQQTSYLKDLDKMHVLAKNEAGFIK 999
Query: 711 YXSLPXITEWNRFLDSKLSXEMXANXXYNEVQWELLMTK 827
P N+FL+ +L E +N + ++W + K
Sbjct: 1000 MIVKPLWETMNKFLNDQL-IEPVSNLENSILEWNKIYEK 1037
>UniRef50_A0BZW8 Cluster: Chromosome undetermined scaffold_14, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_14,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 454
Score = 67.3 bits (157), Expect = 5e-10
Identities = 56/202 (27%), Positives = 94/202 (46%), Gaps = 21/202 (10%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA ++Q + ++ ++ F +EI + +L+ + HD+ H GVN + I
Sbjct: 179 PYHNFTHAFQLSQLLFSCYMKSDLKKFCNQLEIFSAILAGLGHDLNHKGVNNMYKIKK-- 236
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEE-----RPDLQEELKKHLKVL- 404
+ + +L TSE +VLE+ H A II+ + D + L K L +
Sbjct: 237 --SKKFNVL--TSE-IAVLENMHC-ATFFNIIQLNRQHDFFQYMTNDEERNLAKRLIITS 290
Query: 405 IMATDITRQHDYLSRFKK---------------LLDTNTLDMRIQEHRILVLQIALKCAD 539
I+ATD+++ + L++F+K L+D E RI +L I + D
Sbjct: 291 ILATDMSKHNKLLAKFQKRVESTKQFEQGEKNELIDMQRFSNERLEDRIFILNIMVHACD 350
Query: 540 ISNPCRPWSVSQKWSVKVCEEF 605
ISNP ++ WS + +EF
Sbjct: 351 ISNPTMKFNNYMNWSYLLTQEF 372
>UniRef50_Q29FT2 Cluster: GA17041-PA; n=1; Drosophila
pseudoobscura|Rep: GA17041-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 815
Score = 66.9 bits (156), Expect = 6e-10
Identities = 36/93 (38%), Positives = 52/93 (55%)
Frame = +3
Query: 405 IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWS 584
I+ATD+ R ++ L++F ++ T D + H L+ I +K ADISN RP V++ W
Sbjct: 33 ILATDMARHNEILTQFMEI--TPIFDYSNRAHINLLCMILIKVADISNEARPMDVAEPWL 90
Query: 585 VKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
++ +EFF Q EK LPVT D D S P
Sbjct: 91 DRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKP 123
>UniRef50_A2E5S0 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1275
Score = 66.5 bits (155), Expect = 8e-10
Identities = 49/186 (26%), Positives = 92/186 (49%), Gaps = 4/186 (2%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
+P++N A Q ++ L ++ + +E +A ++S I HDI + V+ +T
Sbjct: 1037 SPFYNWQRAVASAQFVYYILTTTDLKNILTDLEKLALIVSTICHDIDYTSVDDSNQ-STE 1095
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCI--IESGLLEE-RPDLQEELKKHLKVLIM 410
LA LY N V+E HH +S + E +LE D + K + LI+
Sbjct: 1096 IALAVLYH-------NRPVMEMHHCEHTISILERSEENILETLNADDSQSCWKMIISLIL 1148
Query: 411 ATDITRQHDYLSRFKKLLDTNTL-DMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSV 587
T++ + + ++ + L+ N + +M+++EHR+L++Q +K +D S CR + V Q+
Sbjct: 1149 GTNMAKHFNTVTTLQSLIFPNKMINMKLEEHRLLIMQFIIKASDASYACRNFPVCQREGT 1208
Query: 588 KVCEEF 605
K + F
Sbjct: 1209 KAYKMF 1214
>UniRef50_Q6CY30 Cluster: Similar to sp|P06776 Saccharomyces
cerevisiae YOR360c PDE2 high affinity 3; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P06776
Saccharomyces cerevisiae YOR360c PDE2 high affinity 3 -
Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 516
Score = 66.1 bits (154), Expect = 1e-09
Identities = 59/201 (29%), Positives = 87/201 (43%), Gaps = 2/201 (0%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMH--CFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
E+ YH N +HN HA DV QA + C LL+ + + C+ +AI HD+ HPG
Sbjct: 257 EAAYHQGNKFHNFRHAVDVLQATYQLCHLLE-----LPKLASFLLCI-AAIGHDVAHPGT 310
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKH 392
N + ++ Y+ SVLE+ H L L P+L +E
Sbjct: 311 NNMLFNKYVSPISKYYK-------EQSVLENFHADIYLDI-----LSHYWPELSQEFTG- 357
Query: 393 LKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVS 572
+K I+ATD+ + Y+ K+ N + + +K ADISN RP +S
Sbjct: 358 IKDSIIATDMALHNHYVETIKQETGPNLTGLT---------SLIIKAADISNVTRPLLIS 408
Query: 573 QKWSVKVCEEFFRQGDYEKML 635
KW+ + EF EK L
Sbjct: 409 AKWAALISMEFKECAVLEKNL 429
>UniRef50_A2DM77 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1072
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/195 (24%), Positives = 93/195 (47%), Gaps = 2/195 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
P+HN A D Q ++ + +G++ ++P E +A +++ + HD+ H GV+ +L T +
Sbjct: 820 PFHNFYLAIDQLQFLNILINEGNLERILQPTEFLALIIATLCHDMGHDGVDNKYLRETNS 879
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQE--ELKKHLKVLIMAT 416
+ + E +EN HH+ + I SGL +LQ+ + ++ LI+++
Sbjct: 880 PIFAAFP--EYPNEN------HHFVILIEVIKRSGLF-NNINLQDTTAIWGVIRDLILSS 930
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
+ + + +++ DM+ R +++++ + D S R W V KWS +
Sbjct: 931 NCDPK-ELQKETNEIVMNGPPDMQNPRTRKVLMRLLVNICDWSYSMRSWDVCDKWSFNLF 989
Query: 597 EEFFRQGDYEKMLDL 641
E F QGD L L
Sbjct: 990 AEHFMQGDLMTELGL 1004
>UniRef50_A0DIM1 Cluster: Chromosome undetermined scaffold_52, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_52, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 779
Score = 65.7 bits (153), Expect = 1e-09
Identities = 55/205 (26%), Positives = 89/205 (43%), Gaps = 7/205 (3%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
NP+HN H V A + + S+ + LLSA+ HDI H G N F
Sbjct: 525 NPFHNYDHGFTVAHACYYIIKSKSMNQYFDKFIQFTALLSALCHDIDHTGRNNHFESQKL 584
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIM 410
+ LA Y + SVLE+HH + + L D + +K+ I+
Sbjct: 585 SKLALRY-------NDESVLENHHASVMFKILQKEKYNILSSLSQDQCQIFRKYAIANIL 637
Query: 411 ATDITRQHDYLS----RFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
TD+ + + + + KL D + + ++ + L I C D++ + + ++QK
Sbjct: 638 GTDMKKHFEIVKLLELKLSKLPDEPFI-QKEEDKKFLSSAIVHTC-DLTMQSKTFKMAQK 695
Query: 579 WSVKVCEEFFRQGDYEKMLDLPVTQ 653
WS ++ EF Q EK L LP+TQ
Sbjct: 696 WSNRIATEFSDQVAEEKQLSLPITQ 720
>UniRef50_Q22CV4 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Tetrahymena thermophila SB210
Length = 1258
Score = 64.9 bits (151), Expect = 2e-09
Identities = 51/194 (26%), Positives = 88/194 (45%), Gaps = 9/194 (4%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRA--FIRPVEIIACLLSAIAHDIFHPGVNQGFLIA 233
N +HN H V Q+ C++L RA ++P++I +LS + HD+ H G F I+
Sbjct: 891 NDFHNFDHGVSVMQS--CYMLSKCQRATQVLKPIDIFTVILSGLCHDVGHTGRTNNFEIS 948
Query: 234 TCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES---GLLEE-RPDLQEELKKHLKV 401
+ LA Y + SVLE HH + +S +L+ P ++++ +
Sbjct: 949 VQSKLAIRY-------HDKSVLEQHHLATTFKIMKQSLDYNILQNLEPITYNQVRRSMIS 1001
Query: 402 LIMATDITRQHDYLSRFK---KLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVS 572
I+ TDI + + F+ K D + L+ + + AD + +P+ +S
Sbjct: 1002 NILYTDIKQHFKLILDFETQWKNYDEQLKTTNSEGEIDLLTGMIIHTADFTGAAKPFPLS 1061
Query: 573 QKWSVKVCEEFFRQ 614
++WS KV EF Q
Sbjct: 1062 RQWSEKVNREFHNQ 1075
>UniRef50_A0E1V7 Cluster: Chromosome undetermined scaffold_74, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_74, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1007
Score = 64.1 bits (149), Expect = 4e-09
Identities = 53/199 (26%), Positives = 87/199 (43%), Gaps = 7/199 (3%)
Frame = +3
Query: 39 ESGYH-STNPYHNSIHATDVTQAMHCFL--LQGSI-RAFIRPVEIIACLLSAIAHDIFHP 206
ES Y+ + NPYHN H V QA++CF+ L + + F + LLSA+ HD+ H
Sbjct: 737 ESQYNMNNNPYHNFDHGVAVMQAVNCFIKSLTNQLDQQFFNNITKFCLLLSALCHDVAHT 796
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI--IESGLLEERPDLQ-E 377
G + + + LA Y + +LE HH + + ++ +L D
Sbjct: 797 GKTNAYEANSISQLAIRY-------HDKVILEQHHAATTIKILRDDQTNILCNFSDQDFR 849
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
+K L I++TD+ L F+ ++ D E L+ + AD + R
Sbjct: 850 TFRKQLISNILSTDMQEHFKMLKEFESRIEQYGND---PEDLSLLCGMITHAADFNGTAR 906
Query: 558 PWSVSQKWSVKVCEEFFRQ 614
W S+ WS K+ +E+ Q
Sbjct: 907 KWPQSRLWSDKINQEYRAQ 925
>UniRef50_A0CU34 Cluster: Chromosome undetermined scaffold_28, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_28, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 903
Score = 62.5 bits (145), Expect = 1e-08
Identities = 60/258 (23%), Positives = 103/258 (39%), Gaps = 9/258 (3%)
Frame = +3
Query: 30 TLFESGYHST-NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
T + Y+ T NP+HN H +V F + A L+ + HD+ HP
Sbjct: 634 TALKYKYNKTANPFHNFTHGVNVMHGCFLFTHHPKFGFCFNDQQRFAMTLAGLCHDVGHP 693
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAA--LSCIIESGLLEERPDLQE- 377
G N F + T LA LY + SVLE+HH L + + LE P +
Sbjct: 694 GTNNLFQVNTQTKLALLY-------NDKSVLENHHIAVTYKLLALEQCDFLESVPRADKL 746
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRI---QEHRILVLQIALKCADISN 548
++K++ ++ATD L+ + + D +I ++++L+ AD
Sbjct: 747 MIRKYIVNNVLATDNQFHFKILNDIEIKFAQSQGDPKIFESDDNKLLLSGFLTHAADFFG 806
Query: 549 PCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDR--DSTSIPXNTNXLL*IYXSL 722
+ + V++ WS ++ EF Q E ++ + T D N L +
Sbjct: 807 AAKSYQVARTWSERLRREFQAQSQLEDIVGIAQTPYLRNLDDEVQYAKNEIGFLKVIVK- 865
Query: 723 PXITEWNRFLDSKLSXEM 776
P N+F D +S ++
Sbjct: 866 PIYESLNQFSDGAMSLQL 883
>UniRef50_A0CZB5 Cluster: Chromosome undetermined scaffold_32, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_32, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1270
Score = 62.1 bits (144), Expect = 2e-08
Identities = 52/202 (25%), Positives = 91/202 (45%), Gaps = 5/202 (2%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
N +HN H V Q+ H L + FI +A ++S + HD+ H G F+I +
Sbjct: 1005 NSFHNYDHGISVMQSAHFMLQCEKAKQFIDDFRRMATIISGLCHDVSHTGRTNVFMINSQ 1064
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVL---IM 410
+ LA Y + S LE HH + + +S L +E+ ++ ++L I+
Sbjct: 1065 SKLATRY-------HDSSPLEQHHAATTIFMLKDSSLNFLSNLTKEQHQQFRRILIDNIL 1117
Query: 411 ATDITRQHDYLSRFK-KLLDTNTLDMRIQEHRI-LVLQIALKCADISNPCRPWSVSQKWS 584
TDI L F+ ++ D T + + L+ + + AD + + + +S+ WS
Sbjct: 1118 YTDIKVHFTLLKDFESRIKDDVTKPFGTGDDDLKLLTGMIIHTADFNGGAKVFDISRIWS 1177
Query: 585 VKVCEEFFRQGDYEKMLDLPVT 650
+V +EF Q + E L +P T
Sbjct: 1178 ERVNKEFSAQYEEEGRLGIPQT 1199
>UniRef50_UPI00006CB6E9 Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 699
Score = 60.9 bits (141), Expect = 4e-08
Identities = 67/271 (24%), Positives = 106/271 (39%), Gaps = 20/271 (7%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
NP+HN H V + Q + I+ + A + S + HD+ H F + +
Sbjct: 304 NPFHNFDHGITVMHGCYMLCCQTVAQTIIKEINEFALIFSGLCHDVSHTARTNLFEVNSM 363
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCII--ESGLLEERPDLQ-EELKKHLKVLIM 410
+ LA Y + SVLE HH + E+ +L + P Q ++++K + I+
Sbjct: 364 SKLAIRYH-------DKSVLEQHHIAVTFKILRKKEANILTQLPLEQVQQIRKIVISNIL 416
Query: 411 ATDITRQHDYLSRFKKLLDTNTL----DMRIQEHRI------------LVLQIALKCADI 542
ATDI + D L F+ L D +I E L+ + + AD
Sbjct: 417 ATDIKQHFDLLKDFELRFGNKGLKLKNDFQINEQECQSVTTYSDNDLNLITNMMIHAADF 476
Query: 543 SNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT-QLCDRDSTSIPXNTNXLL*IYXS 719
+ + +S+KWS+ V +EF Q E ++P T L D D I +
Sbjct: 477 HGNAQEFELSKKWSLLVNQEFQAQYKEEAEKNIPQTPYLKDLDKRDILAKSEIGFINAIV 536
Query: 720 LPXITEWNRFLDSKLSXEMXANXXYNEVQWE 812
P N+FL L N N QW+
Sbjct: 537 KPLWELLNKFLGDDLQISTN-NLSNNIKQWD 566
>UniRef50_A0D565 Cluster: Chromosome undetermined scaffold_38, whole
genome shotgun sequence; n=5; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_38, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 964
Score = 60.9 bits (141), Expect = 4e-08
Identities = 56/261 (21%), Positives = 109/261 (41%), Gaps = 7/261 (2%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCF---LLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
N +HN H V Q H +++ + +LS + HD+ H G F I
Sbjct: 712 NQFHNYDHGVTVMQCTHAISLEIMKTQYAHLLNQFTKFVLILSGLCHDVSHTGRTNIFEI 771
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAA--LSCIIESGLLEERPDLQ-EELKKHLKV 401
+ ++L Y + SVLE HH + L C + ++ ++ + +K
Sbjct: 772 NSLSNLTIRY-------HDRSVLEQHHAATSIKLLCAPSTNIIPNFTSVEFRDFRKLFIS 824
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
I+ TDIT + + F+ + L+ ++ L+ + + +D + +P+++S++W
Sbjct: 825 NILYTDITEHFNLIKNFEARI--KELNFGTEDDIKLMTGMIIHTSDFTGGAKPFNLSREW 882
Query: 582 SVKVCEEFFRQGDYEKMLDLP-VTQLCDRDSTSIPXNTNXLL*IYXSLPXITEWNRFLDS 758
S +V EF Q + E P + + D D I + + P + ++F +
Sbjct: 883 STRVNMEFQEQYNLEGKFGYPQLPYMKDLDQQPIMAKSEVGFFKFIVRPLWSIMSKFAED 942
Query: 759 KLSXEMXANXXYNEVQWELLM 821
+L + N ++WE LM
Sbjct: 943 RLQKSV-ENLEQTILEWEKLM 962
>UniRef50_A2DBZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1126
Score = 60.1 bits (139), Expect = 7e-08
Identities = 49/192 (25%), Positives = 86/192 (44%)
Frame = +3
Query: 30 TLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPG 209
T Y+ +HN HA D TQ + L + + + A L +++ HD+ H G
Sbjct: 878 TFTRENYNENLKFHNFEHALDFTQFVFVCLTRNKFGNCMNVDQKAALLCASLLHDVNHDG 937
Query: 210 VNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKK 389
N FL T ++L DLY G S LE HH AL + +SG+ L++ K+
Sbjct: 938 TNTLFLNQTSSYLVDLY----GKE---STLERHHVSEALRIVEKSGI-----TLKD--KR 983
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
I+ATD+++ + + + L + Q LV + + C +++N RP+
Sbjct: 984 FFVNAILATDMSKFEENVQKVTVLRGKFNKTDKTQVP--LVATLLMMCGNVANTTRPFYF 1041
Query: 570 SQKWSVKVCEEF 605
+ + ++ E+
Sbjct: 1042 ASECGKRILSEY 1053
>UniRef50_A2FK96 Cluster: GAF domain containing protein; n=3;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1174
Score = 59.7 bits (138), Expect = 9e-08
Identities = 52/197 (26%), Positives = 89/197 (45%), Gaps = 2/197 (1%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ T YH P+HN HA DVTQ + + G + + +EI+A L+SAI HD+
Sbjct: 918 RFITSISEQYHHV-PFHNFNHAVDVTQMAYMIVKVGRLFSNFTKLEILALLVSAICHDMG 976
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE 380
H G G L+ L++ + E F + SC I S L D +
Sbjct: 977 HRG-KMGTSSKVQTPLSLLFKD-QPVMETFHCSSAIKTIGKPSCNILSSL---NADQLHD 1031
Query: 381 LKKHLKVLIMATDITRQHDYLSRFKKL--LDTNTLDMRIQEHRILVLQIALKCADISNPC 554
+ I++T+ T QH + KL TL + + R ++++ L+ ++++
Sbjct: 1032 FWVLVIDTILSTE-TSQHQKIIDDAKLSFAPDETLPLANTQQRARMMKLILRIGNLASCA 1090
Query: 555 RPWSVSQKWSVKVCEEF 605
RP+ ++ WS + +EF
Sbjct: 1091 RPFDSTKSWSSVLSDEF 1107
>UniRef50_A2DCH1 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1106
Score = 59.3 bits (137), Expect = 1e-07
Identities = 52/194 (26%), Positives = 89/194 (45%), Gaps = 2/194 (1%)
Frame = +3
Query: 66 YHNSIHATDV-TQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPG-VNQGFLIATC 239
+H+ H+ DV TQ + + + S + P+E ++ ++AI+HD H G VN
Sbjct: 873 FHDYHHSIDVLTQCIQ--MCKSSYGQVLLPIERLSLYIAAISHDSLHDGFVNL------- 923
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVLIMATD 419
L Y L FS +E + + L E+ D + EL I+ATD
Sbjct: 924 -KLGTPYECLL----KFSPMEMRSVDFLRQSVEKFEFLTEK-DAKNELLSEASRFILATD 977
Query: 420 ITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCE 599
+++ D + KKL D++ +E R+ +I +K AD+ + R + K + +
Sbjct: 978 MSKHFDLIEEAKKLADSDNFSFEDKETRMKTTEILIKSADLGSANRNGDKADKKGLP--D 1035
Query: 600 EFFRQGDYEKMLDL 641
EFF +GD K+ D+
Sbjct: 1036 EFFAEGDLSKVKDI 1049
>UniRef50_A0EF18 Cluster: Chromosome undetermined scaffold_92, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_92, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 929
Score = 58.0 bits (134), Expect = 3e-07
Identities = 57/262 (21%), Positives = 115/262 (43%), Gaps = 6/262 (2%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLL----QGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFL 227
NP+HN H +V + H + Q + + ++ +LS + HD+ H G F
Sbjct: 681 NPFHNYNHGVNVMHSCHVIMNKMINQPQYKVLFDQLTKLSLILSGLCHDVGHTGRTNIFE 740
Query: 228 IATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL-LEERPDLQEELKKHLKVL 404
I + A Y + +VLE +H AL +++ + + D ++ +K ++ +
Sbjct: 741 INNFSEKAIRYH-------DKNVLEQYHAATALKLLLKERMNFLKNVDFRQFREKFIQNI 793
Query: 405 IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWS 584
I TD ++H L +F + N D++I + + + +D + W +S++WS
Sbjct: 794 IF-TD-KQEHFNLLKFFEA--NNEKDIKI------ITGMIIHTSDFAGASAKWPISKQWS 843
Query: 585 VKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIPXNTNXLL*IYXSLPXITEWNRFLDSK 761
++V +EF Q + E L LP + D S+ + + P ++F+D +
Sbjct: 844 LRVNQEFQAQFEEEGRLGLPQQPFMKDLQKISVLSKSEIGFYKFFVRPLYVSLSKFMDHQ 903
Query: 762 LSXEMXANXXYNEVQWELLMTK 827
L + N ++W+ L ++
Sbjct: 904 LQDRID-NIDETIIEWDSLASQ 924
>UniRef50_Q5C1P7 Cluster: SJCHGC07646 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07646 protein - Schistosoma
japonicum (Blood fluke)
Length = 219
Score = 56.8 bits (131), Expect = 6e-07
Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 4/121 (3%)
Frame = +3
Query: 114 FLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFS 293
FL IR+ ++ +A LL+AI HD+ HPG FL+ + + LA LY + +
Sbjct: 1 FLQHSLIRSICTNIDEVATLLAAIVHDVDHPGKTNPFLVNSNDPLAILY-------NDIA 53
Query: 294 VLESHHWRAALSCIIESGLLEERPDLQEE----LKKHLKVLIMATDITRQHDYLSRFKKL 461
VLESHH A + S + +L E ++ ++ +++AT++ R D +++F
Sbjct: 54 VLESHHAAVAFELTLRSPDINIFQNLTREEYRTMRSYIVDMVLATEMVRHFDIVTKFVNT 113
Query: 462 L 464
L
Sbjct: 114 L 114
Score = 49.2 bits (112), Expect = 1e-04
Identities = 16/40 (40%), Positives = 32/40 (80%)
Frame = +3
Query: 495 EHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQ 614
E+R L+ ++ +KC+D++NP RP S+ ++W++++ EE+F Q
Sbjct: 169 ENRSLIKRLIIKCSDVNNPTRPLSICKEWAMRIAEEYFCQ 208
>UniRef50_Q5BYM4 Cluster: SJCHGC06481 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06481 protein - Schistosoma
japonicum (Blood fluke)
Length = 178
Score = 56.4 bits (130), Expect = 9e-07
Identities = 26/53 (49%), Positives = 34/53 (64%)
Frame = +3
Query: 507 LVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDR 665
LV+ I LK +DISN RP +V+ W ++ EFF Q DYEK++ LPV DR
Sbjct: 40 LVMVIILKISDISNEARPLNVAGPWINRLLAEFFHQSDYEKLVGLPVAPFMDR 92
>UniRef50_A2F4K8 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1072
Score = 55.2 bits (127), Expect = 2e-06
Identities = 42/201 (20%), Positives = 86/201 (42%), Gaps = 2/201 (0%)
Frame = +3
Query: 30 TLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPG 209
++F S + +HN +H+ D Q G++ + VE+ A L S + + H G
Sbjct: 812 SIFNSSFVEGVAFHNKLHSLDCIQFFMFMNQLGTLGQVLNVVEMHAILASIFCYSMKHDG 871
Query: 210 VNQGFLIATCNHLADL-YRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELK 386
+ H + YR+ VL + L + G+L E +
Sbjct: 872 TTDIYN----EHANTINYRVFGP-----KVLSARARATLLDIYSKEGMLGEMSQNDKNYF 922
Query: 387 KHLKV-LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
++ L+ + D +++ K+++ T+ +D+ EHR++++++ + A I RP+
Sbjct: 923 WNVSTTLLQSIDPADIQPLINKLKEIVKTSLVDLTNTEHRLIIIELIFRAAIIGWTVRPF 982
Query: 564 SVSQKWSVKVCEEFFRQGDYE 626
+S +W +E F G+ E
Sbjct: 983 GISSRWQDLRAQESFALGEKE 1003
>UniRef50_Q4RHZ1 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF15044, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 884
Score = 54.4 bits (125), Expect = 3e-06
Identities = 35/109 (32%), Positives = 57/109 (52%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ T YHN HA +V+Q M + S + + E++A ++ + HD+ H G N F
Sbjct: 639 YRTVAYHNWRHAFNVSQCMFIMITTASFQDVLSDAEVLALMVGCLCHDLDHRGTNNAFQA 698
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQE 377
T + LA LY GTS + LE HH+ A+ I++S + ++ +L E
Sbjct: 699 KTGSALALLY----GTS---ATLEHHHFNHAV-MILQSEVGVDQNELVE 739
Score = 37.1 bits (82), Expect = 0.56
Identities = 21/93 (22%), Positives = 45/93 (48%)
Frame = +3
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
L+ T T +H + + +L + ++ + ++ ++ + D+ RPW +S++
Sbjct: 706 LLYGTSATLEHHHFNHAVMILQS---EVGVDQNELVEVHADDSGCDLGAVTRPWKISKQV 762
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ V EFF QGD E+ +L +T + S+
Sbjct: 763 AELVTSEFFEQGDRER-AELKLTPAVSKKVLSV 794
>UniRef50_Q95Z92 Cluster: Possible phosphodiesterase; n=2;
Leishmania|Rep: Possible phosphodiesterase - Leishmania
major
Length = 725
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/80 (35%), Positives = 40/80 (50%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
KLFT Y N YHN+ HA D Q M F + ++ EI C L+ +A D+
Sbjct: 189 KLFTC----YPLDNSYHNATHAADALQMMSLFFREPTVNFLFSDEEIAICFLAVLAVDVA 244
Query: 201 HPGVNQGFLIATCNHLADLY 260
HPG + L+A + LA ++
Sbjct: 245 HPGASDTLLVALDHPLASVF 264
>UniRef50_A0BZK9 Cluster: Chromosome undetermined scaffold_139, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_139, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 987
Score = 51.6 bits (118), Expect = 2e-05
Identities = 55/203 (27%), Positives = 83/203 (40%), Gaps = 6/203 (2%)
Frame = +3
Query: 54 STNPYHNSIHATDVTQAMHCF---LLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
+ NPYHN H V Q H F L Q S I ++S+ HD+ H G F
Sbjct: 732 NNNPYHNYDHGITVMQTAHYFCSELAQTSKSKIIDNFNRFILMISSFGHDVGHTGKTNVF 791
Query: 225 LIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI--IESGLLEERPDLQ-EELKKHL 395
I + + LA Y + SVLE HH + + +S +L + +K L
Sbjct: 792 EINSLSDLAIRY-------HDKSVLEQHHAALTIQVLKNPQSNILVNLNQQEFRNFRKGL 844
Query: 396 KVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQ 575
I++TD++ L F+ T+ D +I I + +D + ++S
Sbjct: 845 IANILSTDMSEHFTLLKDFEN-RPTDFNDCKILSGYI------MHTSDFGGAGKKTNLSI 897
Query: 576 KWSVKVCEEFFRQGDYEKMLDLP 644
KWS +V +EF Q E L P
Sbjct: 898 KWSSRVNQEFSIQYKLEGELGYP 920
>UniRef50_Q4SV96 Cluster: Chromosome 10 SCAF13771, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF13771, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 816
Score = 51.2 bits (117), Expect = 3e-05
Identities = 21/68 (30%), Positives = 39/68 (57%)
Frame = +3
Query: 477 LDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQL 656
+D + R+LV Q+ +K AD++ P + + +W+ + EF++QGD E L LP++
Sbjct: 619 IDWTNENDRLLVCQMCIKLADVNGPLKCKELHLQWTEGIVNEFYQQGDEEASLGLPISPF 678
Query: 657 CDRDSTSI 680
DR + +
Sbjct: 679 MDRSAPQL 686
Score = 49.2 bits (112), Expect = 1e-04
Identities = 35/113 (30%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
GS+ I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 460 GSLAGLIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQALLY-------NDRSVLEN 512
Query: 306 HHWRAALSCIIESGLLEERPDLQEELKKHLKVL----IMATDITRQHDYLSRF 452
HH +A + + +L+ K + L I+ATD+ + D+L+ F
Sbjct: 513 HHAASAWNLFLSRPEYNFLVNLEHVEFKRFRFLVIEAILATDLKKHFDFLAEF 565
>UniRef50_A2FET3 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1135
Score = 51.2 bits (117), Expect = 3e-05
Identities = 44/184 (23%), Positives = 82/184 (44%), Gaps = 5/184 (2%)
Frame = +3
Query: 42 SGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRA-FIRPVEIIACLLSAIAHDIFHPGVNQ 218
S + N YHN HA + Q + + +G + I P++ A +L+ + HDI H G +
Sbjct: 883 SKLYKNNKYHNWNHAVETVQLCYSIVKRGKMSPRAINPMQTTALILACLLHDICHDGTSN 942
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDL----QEELK 386
+ I + L ++ + EN S+ S LL+ +P EE
Sbjct: 943 EYHIKAKSSLYHVFGD-DCPLENSSLTRSVR------------LLKSQPFFVCINNEEFW 989
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
K ++ATDI + + + +++ D + H + + ++ + A+ISN RP+S
Sbjct: 990 LFFKECLLATDIKKYEETIQNYQQC--ARNFDSKNLIHSVSLAKLVITVANISNVVRPFS 1047
Query: 567 VSQK 578
+Q+
Sbjct: 1048 QAQQ 1051
>UniRef50_A2FCG2 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 439
Score = 51.2 bits (117), Expect = 3e-05
Identities = 43/175 (24%), Positives = 83/175 (47%), Gaps = 3/175 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHNS + D Q ++ L Q + + +E+ A L++++ H+ H G + G LI T
Sbjct: 250 PYHNSDQSLDTLQYVYVILKQTEVSKQLDTIELFALLMASLLHNTNHKGEHGGLLIRTKL 309
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPD-LQEELKKHLKVLIMA 413
L L++ N E+ AA+ + +L+ PD ++ + LI++
Sbjct: 310 PLEILFK-------NQPPAETAQADAAIQLLTNKSVAILDAIPDDVRAKFWNIFTQLILS 362
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
+ I ++ D++ +K D + L+ +++ LK A+ N CRP+ ++ K
Sbjct: 363 SGIYKESDFIQLWKSG-DHSKLNQ---------MRLILKIANSGNVCRPYDIAMK 407
>UniRef50_UPI000065CC62 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited
phosphodiesterase A) (CGI-PDE A).; n=1; Takifugu
rubripes|Rep: cGMP-inhibited 3',5'-cyclic
phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited
phosphodiesterase A) (CGI-PDE A). - Takifugu rubripes
Length = 706
Score = 50.0 bits (114), Expect = 7e-05
Identities = 20/63 (31%), Positives = 37/63 (58%)
Frame = +3
Query: 477 LDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQL 656
+D + R+LV Q+ +K AD++ P + + +W+ + EF++QGD E + LP++
Sbjct: 525 IDWSNENDRLLVCQMCIKLADVNGPLKCKDLHLQWTEGIVNEFYQQGDEESSMGLPISPF 584
Query: 657 CDR 665
DR
Sbjct: 585 MDR 587
Score = 47.6 bits (108), Expect = 4e-04
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 4/113 (3%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 376 GCLSGLIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLY-------NDRSVLEN 428
Query: 306 HHWRAALSCII---ESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRF 452
HH AA + + E L ++ + + L + I+ATD+ + D+L+ F
Sbjct: 429 HHAAAAWNLFMSHPEYNFLVNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEF 481
Score = 33.1 bits (72), Expect = 9.1
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E+GY PYHN IHATDV A+
Sbjct: 300 FHALENGYRDI-PYHNRIHATDVLHAV 325
>UniRef50_UPI000065E700 Cluster: Cone cGMP-specific 3',5'-cyclic
phosphodiesterase subunit alpha' (EC 3.1.4.35) (cGMP
phosphodiesterase 6C).; n=1; Takifugu rubripes|Rep: Cone
cGMP-specific 3',5'-cyclic phosphodiesterase subunit
alpha' (EC 3.1.4.35) (cGMP phosphodiesterase 6C). -
Takifugu rubripes
Length = 937
Score = 48.8 bits (111), Expect = 2e-04
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 5/146 (3%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY + YHN H +V M C L G +R + ++ A + +A HDI H G N +
Sbjct: 634 GYRAIT-YHNWRHGFNVGHTMFCLLQTGKLRKYYSDLDAFAMVAAAFCHDIDHRGTNNLY 692
Query: 225 LIATCNH-LADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK- 398
H LA L+ GT S++E HH + + + E +L +LQ+ +H++
Sbjct: 693 QTKRSAHPLAKLH----GT----SIMERHHLEYSKTLMGEE-VLNIFCNLQKRQFEHVQH 743
Query: 399 ---VLIMATDITRQHDYLSRFKKLLD 467
V I+ATD+ + F+ +++
Sbjct: 744 LFDVCIIATDLALYFKKRTMFQNIVN 769
Score = 35.1 bits (77), Expect = 2.3
Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Frame = +3
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRD 668
D+S +PW V K ++ V EF+ QGD E+ +LD + DR+
Sbjct: 830 DLSAITKPWEVQSKVALMVAAEFWEQGDLERSVLDQQPIPMMDRN 874
>UniRef50_Q4DUD4 Cluster: CAMP-specific phosphodiesterase, putative;
n=2; Trypanosoma|Rep: CAMP-specific phosphodiesterase,
putative - Trypanosoma cruzi
Length = 654
Score = 47.2 bits (107), Expect = 5e-04
Identities = 25/79 (31%), Positives = 37/79 (46%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L LFE+ Y N YHN++HA D Q + L + E+I L+ ++ H
Sbjct: 168 LMALFEN-YSKENAYHNALHAADSVQMLFLILREKPATLIFTENEVILAFLATLSLGFVH 226
Query: 204 PGVNQGFLIATCNHLADLY 260
PGV+ FL + L +Y
Sbjct: 227 PGVSNAFLARIDHPLVLVY 245
>UniRef50_UPI00006A17C5 Cluster: cGMP-inhibited 3',5'-cyclic
phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited
phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).; n=1;
Xenopus tropicalis|Rep: cGMP-inhibited 3',5'-cyclic
phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited
phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1). -
Xenopus tropicalis
Length = 959
Score = 46.8 bits (106), Expect = 7e-04
Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 694 GCLSSNIPALELMALFVAAAMHDYDHPGRTNAFLVATNAPQAVLY-------NDRSVLEN 746
Query: 306 HHWRAALSCII---ESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRF 452
HH +A + + E L +Q + + L + I+ATD+ + D+L+ F
Sbjct: 747 HHAASAWNLFLSQPEHNFLTYLDHVQFKRFRFLVIEAILATDLKKHFDFLAEF 799
>UniRef50_Q4SVG0 Cluster: Chromosome 1 SCAF13759, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 1
SCAF13759, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 954
Score = 46.4 bits (105), Expect = 0.001
Identities = 26/82 (31%), Positives = 40/82 (48%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN H +V Q M L+ G ++ + +E +A + + HDI H G N + + + N
Sbjct: 634 YHNWRHGFNVGQTMFTLLMTGDLKRYYTDLECMAMVTAGFCHDIDHRGTNNLYQMKSGNP 693
Query: 246 LADLYRILEGTSENFSVLESHH 311
LA L+ S+LE HH
Sbjct: 694 LAKLH--------GSSILERHH 707
>UniRef50_Q4QE95 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 1594
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/69 (30%), Positives = 35/69 (50%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ F + + + NP+HN +HA DV A H +L +GS A + E + L +A+ +
Sbjct: 1039 RFFEVAATYFRGGNPFHNPVHAVDVVMAAHQWLNEGSTGAALSDDEAMTFLFTAMVQQLA 1098
Query: 201 HPGVNQGFL 227
H G + L
Sbjct: 1099 HTGADNRLL 1107
>UniRef50_A0CG66 Cluster: Chromosome undetermined scaffold_179, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_179, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1056
Score = 46.0 bits (104), Expect = 0.001
Identities = 54/214 (25%), Positives = 90/214 (42%), Gaps = 12/214 (5%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
NP+HN H V Q+ + +I + A ++S + HDI H G F I +
Sbjct: 792 NPFHNFDHGITVMQSCNFLCSLPRAHEYISEIVYFATVISGLCHDISHTGRTNQFEINSK 851
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVL---IM 410
+ LA Y + S LE+HH L + + + E+L + L I+
Sbjct: 852 SKLATRYL-------DKSPLENHHAAVTLKLLKQDKYNILQGLNAEDLAIFRQTLIENIL 904
Query: 411 ATDITRQH-----DYLSRFKKLLDT-NTLDMRIQEHRILVLQIALKCADISNPCRPWSVS 572
TDI +QH D+ R K+ + + ++ L + + +D S + + +S
Sbjct: 905 FTDI-KQHFGLIKDFEQRVKEGKENQERVFGQVDGDVKLFTGMIVHTSDFSGAAKVFELS 963
Query: 573 QKWSVKVCEEFFRQGDYE---KMLDLPVTQLCDR 665
+ WS KV EF Q D E K++ P + D+
Sbjct: 964 KAWSEKVNMEFQAQFDEEGTRKLISTPFMKDLDK 997
>UniRef50_A2EA57 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1102
Score = 45.2 bits (102), Expect = 0.002
Identities = 43/198 (21%), Positives = 84/198 (42%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
P+HN H+ D Q ++ LL+ + + P +I+ L + + HD+ H G N + N
Sbjct: 861 PFHNFRHSVDCLQFVYYTLLKSRLCNKLDPHQIVGLLFATLLHDVSHNGYNDEY---HKN 917
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVLIMATDI 422
+ LY + +N +E++H + A S II+ E P++ + I AT I
Sbjct: 918 NKTHLYFV-----DNNYPMETYHCKVA-SKIID----EYFPNMNQSFWSMFIPCIKATSI 967
Query: 423 TRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEE 602
+ + SR D I + + ++ +N R + + + + +E
Sbjct: 968 LKLVEMSSRIVMKTD------EISNDFVFISSFVCSMSNTANSFRTFEFGKIMANNIFKE 1021
Query: 603 FFRQGDYEKMLDLPVTQL 656
+ EK +LP++ +
Sbjct: 1022 LTELNEIEKSKNLPLSNM 1039
>UniRef50_Q4DJ46 Cluster: Putative uncharacterized protein; n=2;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 754
Score = 44.4 bits (100), Expect = 0.004
Identities = 43/196 (21%), Positives = 80/196 (40%), Gaps = 11/196 (5%)
Frame = +3
Query: 60 NPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATC 239
NP+HN+ HA+D+ A + FL + + E+ + L ++ + H G+ FLI
Sbjct: 370 NPFHNAYHASDIVLAANQFLSEPHVAENFSDEELFSFLFASTVMKLGHVGMTNAFLIKIH 429
Query: 240 NHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQE-----------ELK 386
+ A LY ++ S+ C + + D EL
Sbjct: 430 HPYAALYGFF-SPQQSVSLALGLTLLDTPECCFPTVASSQESDHDSTPSVWTHEKGVELY 488
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ LI++TD R L++ +++L ++ + H +++LQ L AD R S
Sbjct: 489 EMTAQLIISTDERRHQVLLNQLQQILREGAGNVVRESHLMIILQNVLHAADFCYVFRLSS 548
Query: 567 VSQKWSVKVCEEFFRQ 614
V + + E ++Q
Sbjct: 549 VYRIAAACAVAEVYQQ 564
>UniRef50_UPI00006CD10E Cluster: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3''''5''''-cyclic nucleotide
phosphodiesterase family protein - Tetrahymena
thermophila SB210
Length = 516
Score = 43.2 bits (97), Expect = 0.009
Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA ++Q + I E LLS +AHD+ H GVN L
Sbjct: 229 PYHNWTHAFQLSQMFFTVYFTSDFKDLIDSFEFFVGLLSGLAHDMNHKGVNN--LYKVKR 286
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQE--ELKKHLKVL---I 407
+ R +E +VLE+ H I + + Q+ +L K K+L I
Sbjct: 287 KAENSLRYMEQ-----AVLENMHVSTFFHIISRNPQFDIASKFQDAAKLNKFKKLLVSNI 341
Query: 408 MATDITRQHDYLSRFK 455
+ATD+ R +++ K
Sbjct: 342 LATDMGRHGQFITDLK 357
Score = 35.9 bits (79), Expect = 1.3
Identities = 24/100 (24%), Positives = 44/100 (44%)
Frame = +3
Query: 351 LEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALK 530
+++ P+ + L K+L A + + D + KK + N +I ++ + I +
Sbjct: 366 VKQNPENADPLDKYL-----AFNKDSEQDREVKLKKYIQNN--QQQINNNKQFLTNIMIH 418
Query: 531 CADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
DI NPC + W + +EF Q E+ +PVT
Sbjct: 419 ACDIGNPCYSFDNYMNWCYLLSQEFHDQTIKEEQKGVPVT 458
>UniRef50_Q4RNP2 Cluster: Chromosome 2 SCAF15010, whole genome shotgun
sequence; n=58; Fungi/Metazoa group|Rep: Chromosome 2
SCAF15010, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1093
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 3/108 (2%)
Frame = +3
Query: 264 ILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMATDITRQH 434
+L GTS + LE HH+ A+ + G +L + LK I+ATD+T
Sbjct: 851 LLYGTS---ATLEHHHFNHAVMILQSEGHNIFCNLSSTEYSDLMQLLKQSILATDLTLYF 907
Query: 435 DYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQK 578
+ + F +L+ + ++ HR + + + D+ +PW +S+K
Sbjct: 908 ENRNNFFELVSNGEYNWNVKTHRDMCRSMMMTACDLGAVTKPWDISRK 955
>UniRef50_Q22VA7 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein
- Tetrahymena thermophila SB210
Length = 624
Score = 41.9 bits (94), Expect = 0.020
Identities = 20/52 (38%), Positives = 27/52 (51%)
Frame = +3
Query: 495 EHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
E R +L I L DI NPC ++ WS + +EF Q E+ +LPVT
Sbjct: 508 EDRRFLLNIILHACDIGNPCLEYNNYMNWSYLITQEFSDQTQKEEQYNLPVT 559
>UniRef50_A2FSQ8 Cluster: 3'5'-cyclic nucleotide phosphodiesterase
family protein; n=1; Trichomonas vaginalis G3|Rep:
3'5'-cyclic nucleotide phosphodiesterase family protein -
Trichomonas vaginalis G3
Length = 1017
Score = 41.5 bits (93), Expect = 0.026
Identities = 17/70 (24%), Positives = 34/70 (48%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
H PYHN HA D Q ++ + ++ + ++ +SA+ HD+ H G + + +
Sbjct: 793 HKNYPYHNWSHAVDTLQFLYYLYYRANLTKYFDELQKTCLFISALCHDVSHNGFSSYYHV 852
Query: 231 ATCNHLADLY 260
+ + A L+
Sbjct: 853 SAQSRTALLF 862
>UniRef50_Q6MQQ9 Cluster: Putative uncharacterized protein
precursor; n=1; Bdellovibrio bacteriovorus|Rep: Putative
uncharacterized protein precursor - Bdellovibrio
bacteriovorus
Length = 725
Score = 35.1 bits (77), Expect = 2.3
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +3
Query: 441 LSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSV-KVCEEFFRQG 617
+S K++D NTLDM EHR VLQ + ++ R ++Q + K+ +E +
Sbjct: 252 ISAIAKMIDQNTLDMSNPEHRKAVLQNTCQYTKVAKKVRFMQLAQSGKIEKITQELEKNV 311
Query: 618 D-YEKMLDLPVTQLCD 662
D Y P +L +
Sbjct: 312 DLYNAKFAKPTGELAN 327
>UniRef50_Q8STT1 Cluster: Putative uncharacterized protein
ECU09_0790; n=1; Encephalitozoon cuniculi|Rep: Putative
uncharacterized protein ECU09_0790 - Encephalitozoon
cuniculi
Length = 350
Score = 35.1 bits (77), Expect = 2.3
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 13/204 (6%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQG-SIRAFIRPVEIIACLLSAIA-HDIFHPGV-NQGFLIAT 236
YHN H + T F+LQ + P+ CL+ A+ HDI HPG N+G + A
Sbjct: 94 YHNLDHLVN-TLCFGDFILQRLGEGGYTLPILDKMCLMIALGLHDIGHPGERNRGKIGA- 151
Query: 237 CNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKK-HLKVLIMA 413
L+ Y + S F ++ + R +S + L D + E ++ ++ +I A
Sbjct: 152 ---LSSSYGGPKAIS--FELIHASICRKMVSAYRHT-LFAGLDDAETERRQGFIEKMIFA 205
Query: 414 TDITRQHDYLSRFK-KLLDTNT---LDMRIQ-----EHRILVLQIALKCADISNPCRPWS 566
TD+ + + F K + T ++ R++ E + L + +K AD+S+ + +
Sbjct: 206 TDLKLNAEIIGAFDAKYFEKETQGSMERRVRNGVGGEISEIELMMIMKIADLSSCYKDYR 265
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLD 638
+ K S+ E + DY + L+
Sbjct: 266 IFNKNSIAFWAEVYDDDDYNRTLE 289
>UniRef50_Q6UWE0 Cluster: E3 ubiquitin-protein ligase LRSAM1; n=33;
Euteleostomi|Rep: E3 ubiquitin-protein ligase LRSAM1 -
Homo sapiens (Human)
Length = 723
Score = 35.1 bits (77), Expect = 2.3
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 315 RAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQ 494
R ALS +++ LL+E+ +EEL++ L L ++ +++ +L ++++LL+ L +++Q
Sbjct: 508 RWALSSLLQQ-LLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQ 566
Query: 495 E 497
E
Sbjct: 567 E 567
>UniRef50_Q53S13 Cluster: Putative uncharacterized protein PDE11A;
n=4; Deuterostomia|Rep: Putative uncharacterized protein
PDE11A - Homo sapiens (Human)
Length = 125
Score = 34.7 bits (76), Expect = 3.0
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +3
Query: 525 LKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKM-LDLPVTQLCDRD 668
+ D+ +PW +S++ + V EFF QGD E++ L L + + DR+
Sbjct: 4 MTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRN 52
>UniRef50_Q0S6Y0 Cluster: Probable CoA-transferase; n=3;
Actinomycetales|Rep: Probable CoA-transferase -
Rhodococcus sp. (strain RHA1)
Length = 417
Score = 34.3 bits (75), Expect = 4.0
Identities = 24/77 (31%), Positives = 41/77 (53%)
Frame = +3
Query: 357 ERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCA 536
ERP +EL+ + + D + + ++R KK + LD+R +E R LVL +A KC
Sbjct: 42 ERPKTGDELRNWR---LYSGDTSMLYRTINRNKKSI---VLDLRTEEGRQLVLDLAAKCD 95
Query: 537 DISNPCRPWSVSQKWSV 587
+ RP ++ +KW +
Sbjct: 96 ILLENFRPGTL-EKWGI 111
>UniRef50_A0YBF8 Cluster: Putative uncharacterized protein; n=1;
marine gamma proteobacterium HTCC2143|Rep: Putative
uncharacterized protein - marine gamma proteobacterium
HTCC2143
Length = 560
Score = 34.3 bits (75), Expect = 4.0
Identities = 18/76 (23%), Positives = 39/76 (51%)
Frame = +3
Query: 279 SENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKK 458
S+ S + +A+ C+ + G +++R D+ E + H KV ++ T+ + L +
Sbjct: 64 SDKLSYADIDDIKASAVCLRDFGFIDQRADIDERIALHTKVELLQWLPTQTNAKLLKRPA 123
Query: 459 LLDTNTLDMRIQEHRI 506
LLD LD+ + + ++
Sbjct: 124 LLDLIRLDVDVLQQQL 139
>UniRef50_UPI00015B5A6A Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1805
Score = 33.5 bits (73), Expect = 6.9
Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = +3
Query: 285 NFSVLESHH-WRAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKL 461
N SVL S W ++ ++ L +ER +++E + ++ T + +H L FK+L
Sbjct: 1635 NMSVLLSEKKWIGSVQTLVVRSLQDERVEVRERAAQVFNGMLHCTLVDDEHALLEEFKRL 1694
Query: 462 LDTNTLDMRIQEHRI-LVLQIALKCADISNPC 554
T + R Q + + I L+ A + C
Sbjct: 1695 AKTKLRNKRNQSTNVDMSNAIRLRHAGVLGMC 1726
>UniRef50_A2G4P7 Cluster: GAF domain containing protein; n=1;
Trichomonas vaginalis G3|Rep: GAF domain containing
protein - Trichomonas vaginalis G3
Length = 1554
Score = 33.1 bits (72), Expect = 9.1
Identities = 22/96 (22%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Frame = +3
Query: 339 ESGLLEE-RPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNT-LDMRIQEHRILV 512
E +LE + D Q + K ATD++R + + ++ L+ D + H +
Sbjct: 1158 ECNILENIKEDEQRNIWKDTFRFAHATDLSRHFEIMDTLQQCLEEEDGFDSSKETHLNAM 1217
Query: 513 LQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGD 620
L +KCAD+ + P + ++ + +FF G+
Sbjct: 1218 LDAVMKCADLHDVILPLNELEEKRYEFSRDFFMFGE 1253
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 811,776,013
Number of Sequences: 1657284
Number of extensions: 16361833
Number of successful extensions: 40400
Number of sequences better than 10.0: 209
Number of HSP's better than 10.0 without gapping: 38696
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40135
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 75013275813
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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