Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= FWDP01_FL5_A24
(851 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U67932-1|AAB65772.1| 456|Homo sapiens cAMP phosphodiesterase PD... 249 9e-66
L12052-1|AAA35644.2| 482|Homo sapiens cAMP phosphodiesterase PD... 249 9e-66
BC126360-1|AAI26361.1| 456|Homo sapiens phosphodiesterase 7A pr... 249 9e-66
EF108327-1|ABL14249.1| 502|Homo sapiens phosphodiesterase PDE7B... 246 6e-65
BC075083-1|AAH75083.1| 450|Homo sapiens phosphodiesterase 7B pr... 246 6e-65
BC075082-1|AAH75082.1| 450|Homo sapiens phosphodiesterase 7B pr... 246 6e-65
AL360178-1|CAH73075.1| 450|Homo sapiens phosphodiesterase 7B pr... 246 6e-65
AL138828-4|CAI95287.1| 450|Homo sapiens phosphodiesterase 7B pr... 246 6e-65
AL133319-1|CAH73332.1| 450|Homo sapiens phosphodiesterase 7B pr... 246 6e-65
AJ251860-1|CAB92441.1| 450|Homo sapiens phosphodiesterase 7B pr... 246 6e-65
AB209990-1|BAE06072.1| 586|Homo sapiens PDE7B variant protein p... 246 6e-65
AB038040-1|BAA96537.1| 450|Homo sapiens cyclic nucleotide phosp... 246 6e-65
AF332652-1|AAK57640.1| 424|Homo sapiens cAMP-specific cyclic nu... 229 7e-60
AF536977-1|AAN10119.1| 687|Homo sapiens cAMP-specific phosphodi... 135 2e-31
U50159-1|AAA97892.1| 673|Homo sapiens cAMP-specific phoshodiest... 133 9e-31
U50158-1|AAA97891.1| 507|Homo sapiens cAMP-specific phosphodies... 133 9e-31
U50157-1|AAA97890.1| 585|Homo sapiens cAMP-specific phosphodies... 133 9e-31
L20970-1|AAA03592.1| 673|Homo sapiens phosphodiesterase protein. 133 9e-31
L20969-1|AAC00042.1| 809|Homo sapiens cyclic AMP phosphodiester... 133 9e-31
AY388960-1|AAQ90404.1| 679|Homo sapiens cAMP-specific phosphodi... 133 9e-31
AY245867-1|AAP75761.1| 679|Homo sapiens cAMP-specific phosphodi... 133 9e-31
AY245866-1|AAP75760.1| 748|Homo sapiens cAMP-specific phosphodi... 133 9e-31
AF536976-1|AAN10118.1| 748|Homo sapiens cAMP-specific phosphodi... 133 9e-31
AF536975-1|AAN10117.1| 518|Homo sapiens cAMP-specific phosphodi... 133 9e-31
AF012074-1|AAC00070.1| 507|Homo sapiens cAMP-specific phosphodi... 133 9e-31
AF012073-1|AAC00069.1| 745|Homo sapiens cAMP-specific phosphodi... 133 9e-31
BC075822-1|AAH75822.1| 829|Homo sapiens phosphodiesterase 8A pr... 132 2e-30
BC060762-1|AAH60762.1| 829|Homo sapiens phosphodiesterase 8A pr... 132 2e-30
BC048317-1|AAH48317.1| 305|Homo sapiens PDE8A protein protein. 132 2e-30
AF388187-1|AAL18614.1| 582|Homo sapiens cAMP phosphodiesterase ... 132 2e-30
AF388186-1|AAL18613.1| 582|Homo sapiens cAMP phosphodiesterase ... 132 2e-30
AF388185-1|AAL18612.1| 449|Homo sapiens cAMP phosphodiesterase ... 132 2e-30
AF388184-1|AAL18611.1| 783|Homo sapiens cAMP phosphodiesterase ... 132 2e-30
AF388183-1|AAL18610.1| 829|Homo sapiens cAMP phosphodiesterase ... 132 2e-30
AF332653-1|AAK57641.1| 829|Homo sapiens cAMP-specific cyclic nu... 132 2e-30
AF056490-1|AAC39763.1| 713|Homo sapiens cAMP-specific phosphodi... 132 2e-30
BC036319-1|AAH36319.1| 518|Homo sapiens PDE4D protein protein. 131 3e-30
U02882-1|AAC13745.1| 604|Homo sapiens 3',5'-cyclic AMP phosphod... 130 6e-30
U88713-1|AAC51916.1| 700|Homo sapiens phosphodiesterase 4C prot... 128 3e-29
U88712-1|AAC51915.1| 606|Homo sapiens phosphodiesterase 4C prot... 128 3e-29
U66348-1|AAB96877.1| 518|Homo sapiens PDE4C-delta54 protein. 128 3e-29
U66347-1|AAB96876.1| 426|Homo sapiens PDE4C-426 protein. 128 3e-29
U66346-1|AAB96875.1| 791|Homo sapiens PDE4C-791 protein. 128 3e-29
BC109068-1|AAI09069.1| 549|Homo sapiens PDE4C protein protein. 128 3e-29
BC109067-1|AAI09068.1| 481|Homo sapiens PDE4C protein protein. 128 3e-29
AF157816-3|AAD47055.1| 606|Homo sapiens cAMP specific phosphodi... 128 3e-29
AF157816-2|AAD47054.1| 680|Homo sapiens cAMP specific phosphodi... 128 3e-29
AF157816-1|AAD47053.1| 712|Homo sapiens cAMP specific phosphodi... 128 3e-29
AC005759-5|AAC83049.1| 426|Homo sapiens PDE4C-426 protein. 128 3e-29
AC005759-3|AAC83051.1| 518|Homo sapiens PDE4C-delta54 protein. 128 3e-29
AC005759-1|AAC83050.1| 782|Homo sapiens PDE4C-791 protein. 128 3e-29
U97584-1|AAC25679.1| 647|Homo sapiens cyclic AMP-specific phosp... 127 6e-29
U68532-1|AAC63832.1| 647|Homo sapiens cyclic AMP specific phosp... 127 6e-29
U18088-1|AAA98540.1| 323|Homo sapiens 3',5'-cyclic AMP phosphod... 127 6e-29
U18087-1|AAC50458.1| 686|Homo sapiens 3',5'-cyclic AMP phosphod... 127 6e-29
S75213-1|AAB33798.1| 667|Homo sapiens type-IVA cyclic AMP speci... 127 6e-29
M37744-1|AAA69697.1| 775|Homo sapiens protein ( Human cyclic AM... 127 6e-29
L20965-1|AAA03588.1| 886|Homo sapiens phosphodiesterase protein. 127 6e-29
BC038234-1|AAH38234.1| 647|Homo sapiens phosphodiesterase 4A, c... 127 6e-29
BC019864-1|AAH19864.1| 647|Homo sapiens phosphodiesterase 4A, c... 127 6e-29
AY618547-1|AAU82096.1| 860|Homo sapiens cyclic AMP phosphodiest... 127 6e-29
AY593872-1|AAT00628.1| 864|Homo sapiens cAMP-specific phosphodi... 127 6e-29
AF073745-1|AAD34217.2| 825|Homo sapiens cyclic AMP-specific pho... 127 6e-29
AF069491-4|AAC35014.1| 323|Homo sapiens cAMP specific phosphodi... 127 6e-29
AF069491-3|AAC35013.1| 647|Homo sapiens cAMP specific phosphodi... 127 6e-29
AF069491-2|AAC35015.1| 860|Homo sapiens putative novel cAMP spe... 127 6e-29
AF069491-1|AAC35012.1| 886|Homo sapiens cAMP specific phosphodi... 127 6e-29
Z46632-1|CAA86601.1| 712|Homo sapiens 3',5'-cyclic AMP phosphod... 126 8e-29
U85048-1|AAB96381.1| 721|Homo sapiens cyclic AMP specific phosp... 126 1e-28
M97515-1|AAA36426.1| 564|Homo sapiens phosphodiesterase protein. 126 1e-28
L20971-1|AAA03593.1| 564|Homo sapiens phosphodiesterase protein. 126 1e-28
L20966-1|AAA03589.1| 736|Homo sapiens phosphodiesterase protein. 126 1e-28
L12686-1|AAA35643.1| 606|Homo sapiens 3',5'-cyclic AMP phosphod... 126 1e-28
EF595686-1|ABQ85407.1| 503|Homo sapiens cAMP-specific phosphodi... 126 1e-28
BC105040-1|AAI05041.1| 736|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
BC101480-1|AAI01481.1| 736|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AL592285-3|CAH70628.1| 721|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AL592285-1|CAH70626.1| 736|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AL359701-3|CAI23101.1| 721|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AL359701-2|CAI23100.1| 564|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AL359701-1|CAI23099.1| 736|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AL357273-3|CAH73004.1| 721|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AL357273-1|CAH73002.1| 736|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AL109926-4|CAI21751.1| 721|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AL109926-3|CAI21750.1| 564|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AL109926-2|CAI21749.1| 736|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AB209081-1|BAD92318.1| 726|Homo sapiens phosphodiesterase 4B, c... 126 1e-28
AY423729-1|AAS00492.1| 350|Homo sapiens proliferation-inducing ... 124 4e-28
AY129950-3|AAN71727.1| 788|Homo sapiens cAMP-specific phosphodi... 124 4e-28
AY129950-2|AAN71726.1| 838|Homo sapiens cAMP-specific phosphodi... 124 4e-28
AY129950-1|AAN71725.1| 885|Homo sapiens cAMP-specific phosphodi... 124 4e-28
AY129949-1|AAN71724.1| 788|Homo sapiens cAMP-specific phosphodi... 124 4e-28
AY129948-1|AAN71723.1| 838|Homo sapiens cAMP-specific phosphodi... 124 4e-28
AL831924-1|CAD38584.1| 843|Homo sapiens hypothetical protein pr... 124 4e-28
AF079529-1|AAC69564.2| 885|Homo sapiens cAMP-specific phosphodi... 124 4e-28
AB085827-1|BAC53765.1| 865|Homo sapiens phosphodiesterase 8B4 p... 124 4e-28
AB085826-1|BAC53764.1| 830|Homo sapiens phosphodiesterase 8B3 p... 124 4e-28
AB085825-1|BAC53763.1| 788|Homo sapiens phosphodiestearse 8B2 p... 124 4e-28
AB085824-1|BAC53762.1| 885|Homo sapiens phosphodiesterase 8B1 p... 124 4e-28
U86078-1|AAC51872.1| 536|Homo sapiens calmodulin-stimulated pho... 124 5e-28
U56976-1|AAC50769.1| 536|Homo sapiens calmodulin dependent phos... 124 5e-28
BX538092-1|CAD98011.1| 399|Homo sapiens hypothetical protein pr... 124 5e-28
BC035144-1|AAH35144.1| 385|Homo sapiens PDE8B protein protein. 124 5e-28
BC032226-1|AAH32226.1| 536|Homo sapiens phosphodiesterase 1B, c... 124 5e-28
AJ401609-1|CAC82207.1| 516|Homo sapiens 3'5' cyclic nucleotide ... 124 5e-28
AC005759-2|AAC83047.1| 710|Homo sapiens CN4C_HUMAN protein. 123 7e-28
U40370-1|AAC50436.1| 535|Homo sapiens 3',5' cyclic nucleotide p... 120 5e-27
BC022480-1|AAH22480.1| 545|Homo sapiens phosphodiesterase 1A, c... 120 5e-27
AL110263-1|CAB53703.1| 519|Homo sapiens hypothetical protein pr... 120 5e-27
AJ401610-1|CAC82208.1| 519|Homo sapiens 3'5' cyclic nucleotide ... 120 5e-27
AB038224-9|BAB20054.1| 518|Homo sapiens calmodulin-dependent ph... 120 5e-27
AB038224-8|BAB20053.1| 501|Homo sapiens calmodulin-dependent ph... 120 5e-27
AB038224-7|BAB20057.1| 511|Homo sapiens calmodulin-dependent ph... 120 5e-27
AB038224-6|BAB20052.1| 552|Homo sapiens calmodulin-dependent ph... 120 5e-27
AB038224-5|BAB20050.1| 535|Homo sapiens calmodulin-dependent ph... 120 5e-27
AB038224-4|BAB20056.1| 545|Homo sapiens calmodulin-dependent ph... 120 5e-27
AB038224-3|BAB20051.1| 536|Homo sapiens calmodulin-dependent ph... 120 5e-27
AB038224-2|BAB20049.1| 519|Homo sapiens calmodulin-dependent ph... 120 5e-27
AB038224-1|BAB20055.1| 529|Homo sapiens calmodulin-dependent ph... 120 5e-27
U40372-1|AAA96961.1| 564|Homo sapiens PDE1C3 protein. 119 1e-26
U40371-1|AAC50437.1| 634|Homo sapiens 3',5' cyclic nucleotide p... 119 1e-26
BC022525-1|AAH22525.1| 634|Homo sapiens PDE1C protein protein. 119 1e-26
BC022479-1|AAH22479.1| 634|Homo sapiens PDE1C protein protein. 119 1e-26
AK091734-1|BAC03734.1| 769|Homo sapiens (EC 3.1.4.17). protein. 119 1e-26
AC006377-1|AAS07516.1| 591|Homo sapiens unknown protein. 119 1e-26
BT007016-1|AAP35662.1| 533|Homo sapiens phosphodiesterase 9A pr... 111 2e-24
BC009047-1|AAH09047.1| 533|Homo sapiens phosphodiesterase 9A pr... 111 2e-24
AY701187-1|AAV84271.1| 485|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY242121-1|AAO88210.1| 492|Homo sapiens type 9 cGMP-specific ph... 111 2e-24
AY196314-1|AAO34700.1| 386|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196313-1|AAO34699.1| 386|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196312-1|AAO34698.1| 567|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196311-1|AAO34697.1| 552|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196310-1|AAO34696.1| 526|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196309-1|AAO34695.1| 376|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196308-1|AAO34694.1| 386|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196307-1|AAO34693.1| 491|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196306-1|AAO34692.1| 459|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196305-1|AAO34691.1| 376|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196304-1|AAO34690.1| 433|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196303-1|AAO34689.1| 507|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196302-1|AAO34688.1| 386|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196301-1|AAO34687.1| 386|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196300-1|AAO34686.1| 492|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AY196299-1|AAO34685.1| 540|Homo sapiens phosphodiesterase PDE9A... 111 2e-24
AP001747-1|BAA95552.1| 593|Homo sapiens CGMP-specific 3',5'-cyc... 111 2e-24
AF067226-1|AAC26726.1| 465|Homo sapiens cGMP phosphodiesterase ... 111 2e-24
AF067225-1|AAC26725.1| 466|Homo sapiens cGMP phosphodiesterase ... 111 2e-24
AF067224-1|AAC26724.1| 533|Homo sapiens cGMP phosphodiesterase ... 111 2e-24
AF067223-1|AAC26723.1| 593|Homo sapiens cGMP phosphodiesterase ... 111 2e-24
AF048837-1|AAC39778.1| 593|Homo sapiens cGMP-specific phosphodi... 111 2e-24
AB017602-1|BAA88847.1| 593|Homo sapiens cGMP phosphodiesterase ... 111 2e-24
AL138828-3|CAI95286.1| 199|Homo sapiens phosphodiesterase 7B pr... 109 2e-23
U67733-1|AAC51320.1| 941|Homo sapiens PDE2A3 protein. 98 4e-20
BC040974-1|AAH40974.1| 941|Homo sapiens phosphodiesterase 2A, c... 98 4e-20
AK131525-1|BAD18664.1| 685|Homo sapiens protein ( Homo sapiens ... 98 4e-20
BC114431-1|AAI14432.1| 934|Homo sapiens phosphodiesterase 11A p... 97 7e-20
BC112393-1|AAI12394.1| 934|Homo sapiens phosphodiesterase 11A p... 97 7e-20
AJ278682-1|CAC15567.1| 684|Homo sapiens cAMP/cGMP cyclic nucleo... 97 7e-20
AJ251509-1|CAB82573.1| 490|Homo sapiens cyclic nucleotide phosp... 97 7e-20
AF281865-1|AAG32023.1| 576|Homo sapiens cAMP/cGMP phosphodieste... 97 7e-20
AB048423-3|BAB62714.1| 490|Homo sapiens phosphodiesterase 11A1 ... 97 7e-20
AB048423-2|BAB62712.1| 934|Homo sapiens phosphodiesterase 11A4 ... 97 7e-20
AB048423-1|BAB62713.2| 684|Homo sapiens phosphodiesterase 11A3 ... 97 7e-20
AB038041-1|BAB16372.1| 684|Homo sapiens phosphodiesterase 11A3 ... 97 7e-20
AB036704-1|BAB16371.1| 934|Homo sapiens phosphodiesterase 11A p... 97 7e-20
U66349-1|AAB96878.1| 427|Homo sapiens PDE4C-delta109 protein. 96 1e-19
AY495087-1|AAS75513.1| 932|Homo sapiens cGMP-stimulated phospho... 96 1e-19
AC005759-4|AAC83048.1| 427|Homo sapiens PDE4C-delta109 protein. 96 1e-19
D89094-1|BAA28945.1| 875|Homo sapiens 3',5'-cyclic GMP phosphod... 94 7e-19
BC126233-1|AAI26234.1| 875|Homo sapiens phosphodiesterase 5A, c... 94 7e-19
AY264918-1|AAP21809.1| 833|Homo sapiens phosphodiesterase 5A pr... 94 7e-19
AJ004865-1|CAA06170.1| 875|Homo sapiens cGMP-binding, cGMP-spec... 94 7e-19
AF043731-1|AAC63967.1| 875|Homo sapiens cGMP-binding cGMP-speci... 94 7e-19
AC093752-1|AAY40985.1| 331|Homo sapiens unknown protein. 94 7e-19
AB001635-1|BAA33372.2| 875|Homo sapiens cGMP-binding cGMP-speci... 94 7e-19
U36798-1|AAB18673.1| 1141|Homo sapiens platelet cGI-PDE protein. 93 2e-18
M91667-1|AAA35912.2| 1141|Homo sapiens cGMP-inhibited cAMP phosp... 93 2e-18
BC117371-1|AAI17372.1| 1141|Homo sapiens phosphodiesterase 3A, c... 93 2e-18
BC117369-1|AAI17370.1| 1141|Homo sapiens phosphodiesterase 3A, c... 93 2e-18
AJ005036-1|CAA06304.1| 1141|Homo sapiens phosphodiesterase 3A pr... 93 2e-18
AB015656-1|BAA81667.1| 833|Homo sapiens cGMP-binding cGMP speci... 91 5e-18
X95520-1|CAA64774.1| 1112|Homo sapiens cyclic nucleotide phospho... 90 1e-17
U38178-1|AAC50724.1| 1112|Homo sapiens cyclic nucleotide phophod... 90 1e-17
D50640-1|BAA09306.1| 1112|Homo sapiens phosphodiesterase 3B prot... 90 1e-17
BC150307-1|AAI50308.1| 1112|Homo sapiens phosphodiesterase 3B, c... 90 1e-17
AY459346-1|AAR24292.1| 1112|Homo sapiens cGMP-inhibited cAMP pho... 90 1e-17
BC047627-1|AAH47627.1| 241|Homo sapiens PDE8B protein protein. 89 1e-17
U40584-1|AAB50018.1| 184|Homo sapiens calcium/calmodulin-stimul... 89 2e-17
X90587-1|CAA62215.1| 617|Homo sapiens Rod cGMP phosphodiesteras... 76 2e-13
X66142-1|CAA46932.1| 854|Homo sapiens 3',5'-cyclic-nucleotide ... 76 2e-13
X62692-1|CAA44569.1| 854|Homo sapiens cGMP phosphodiesterase be... 76 2e-13
S41458-1|AAB22690.1| 854|Homo sapiens rod cGMP phosphodiesteras... 76 2e-13
X94354-1|CAA64079.1| 858|Homo sapiens cone cGMP phosphodiestera... 75 3e-13
U31973-1|AAA96392.1| 858|Homo sapiens phosphodiesterase A' subu... 75 3e-13
U20212-1|AAA92886.1| 858|Homo sapiens cone photoreceptor cGMP-p... 75 3e-13
AL356214-7|CAH72330.1| 858|Homo sapiens phosphodiesterase 6C, c... 75 3e-13
AL157396-4|CAH73839.1| 858|Homo sapiens phosphodiesterase 6C, c... 75 3e-13
BT009794-1|AAP88796.1| 853|Homo sapiens phosphodiesterase 6B, c... 75 4e-13
BC000249-1|AAH00249.1| 853|Homo sapiens phosphodiesterase 6B, c... 75 4e-13
M26061-1|AAB69155.1| 860|Homo sapiens PDEA protein. 74 6e-13
BC035909-1|AAH35909.1| 860|Homo sapiens phosphodiesterase 6A, c... 74 6e-13
CR536567-1|CAG38804.1| 779|Homo sapiens PDE10A protein. 72 2e-12
AL109778-1|CAB52432.1| 178|Homo sapiens PDE8A; phosphodiesteras... 72 3e-12
AL109687-1|CAB52020.1| 160|Homo sapiens PDE8A; phosphodiesteras... 72 3e-12
BC104860-1|AAI04861.1| 779|Homo sapiens phosphodiesterase 10A p... 71 4e-12
BC104858-1|AAI04859.1| 779|Homo sapiens phosphodiesterase 10A p... 71 4e-12
AL160160-1|CAH72023.1| 779|Homo sapiens phosphodiesterase 10A p... 71 4e-12
AL136130-1|CAI20436.1| 779|Homo sapiens phosphodiesterase 10A p... 71 4e-12
AL117345-1|CAB92797.2| 779|Homo sapiens phosphodiesterase 10A p... 71 4e-12
AF127480-1|AAD32596.1| 807|Homo sapiens 3',5'-cyclic nucleotide... 71 4e-12
AF127479-1|AAD32595.1| 779|Homo sapiens 3',5'-cyclic nucleotide... 71 4e-12
AB041798-3|BAB16383.1| 714|Homo sapiens phosphodiesterase 10A1 ... 71 4e-12
AB026816-1|BAA84467.1| 789|Homo sapiens 3',5'-cyclic nucleotide... 71 4e-12
AB020593-1|BAA78034.1| 779|Homo sapiens 3',5'-Cyclic nucleotide... 71 4e-12
L20968-1|AAA03591.1| 251|Homo sapiens phosphodiesterase protein. 67 7e-11
M94539-1|AAA58405.1| 116|Homo sapiens cyclic nucleotide phospho... 66 2e-10
U86077-1|AAC51871.1| 71|Homo sapiens calmodulin-stimulated pho... 60 8e-09
AY266362-1|AAP31234.1| 102|Homo sapiens phosphodiesterase isozy... 60 8e-09
AC012499-1|AAY14803.1| 325|Homo sapiens unknown protein. 58 3e-08
BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and... 35 0.33
AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein pr... 35 0.33
AL445222-17|CAH72931.1| 696|Homo sapiens leucine rich repeat an... 35 0.33
AL445222-16|CAH72930.1| 723|Homo sapiens leucine rich repeat an... 35 0.33
AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens ... 35 0.33
AK056305-1|BAB71144.1| 303|Homo sapiens protein ( Homo sapiens ... 35 0.33
AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens ... 35 0.33
AC073834-2|AAX93113.1| 125|Homo sapiens unknown protein. 35 0.43
>U67932-1|AAB65772.1| 456|Homo sapiens cAMP phosphodiesterase PDE7
protein.
Length = 456
Score = 249 bits (610), Expect = 9e-66
Identities = 122/265 (46%), Positives = 168/265 (63%), Gaps = 1/265 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + + P +I+ L++A HD+
Sbjct: 170 RFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLD 229
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T ++LA LY+ N SVLE+HHWR+A+ + ESGL P + ++
Sbjct: 230 HPGVNQPFLIKTNHYLATLYK-------NTSVLENHHWRSAVGLLRESGLFSHLPLESRQ 282
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
+++ + LI+ATDI+RQ++YLS F+ LD L + HR LVLQ+ALKCADI NPCR
Sbjct: 283 QMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLEDTRHRHLVLQMALKCADICNPCR 342
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS KV EEFF QGD EK L V+ LCDR + SI N Y P TE
Sbjct: 343 TWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESI-ANIQIGFMTYLVEPLFTE 401
Query: 738 WNRFLDSKLSXEMXANXXYNEVQWE 812
W RF +++LS M + N+ W+
Sbjct: 402 WARFSNTRLSQTMLGHVGLNKASWK 426
>L12052-1|AAA35644.2| 482|Homo sapiens cAMP phosphodiesterase PDE7
protein.
Length = 482
Score = 249 bits (610), Expect = 9e-66
Identities = 122/265 (46%), Positives = 168/265 (63%), Gaps = 1/265 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + + P +I+ L++A HD+
Sbjct: 196 RFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLD 255
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T ++LA LY+ N SVLE+HHWR+A+ + ESGL P + ++
Sbjct: 256 HPGVNQPFLIKTNHYLATLYK-------NTSVLENHHWRSAVGLLRESGLFSHLPLESRQ 308
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
+++ + LI+ATDI+RQ++YLS F+ LD L + HR LVLQ+ALKCADI NPCR
Sbjct: 309 QMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLEDTRHRHLVLQMALKCADICNPCR 368
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS KV EEFF QGD EK L V+ LCDR + SI N Y P TE
Sbjct: 369 TWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESI-ANIQIGFMTYLVEPLFTE 427
Query: 738 WNRFLDSKLSXEMXANXXYNEVQWE 812
W RF +++LS M + N+ W+
Sbjct: 428 WARFSNTRLSQTMLGHVGLNKASWK 452
>BC126360-1|AAI26361.1| 456|Homo sapiens phosphodiesterase 7A
protein.
Length = 456
Score = 249 bits (610), Expect = 9e-66
Identities = 122/265 (46%), Positives = 168/265 (63%), Gaps = 1/265 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + + P +I+ L++A HD+
Sbjct: 170 RFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLD 229
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T ++LA LY+ N SVLE+HHWR+A+ + ESGL P + ++
Sbjct: 230 HPGVNQPFLIKTNHYLATLYK-------NTSVLENHHWRSAVGLLRESGLFSHLPLESRQ 282
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
+++ + LI+ATDI+RQ++YLS F+ LD L + HR LVLQ+ALKCADI NPCR
Sbjct: 283 QMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLEDTRHRHLVLQMALKCADICNPCR 342
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS KV EEFF QGD EK L V+ LCDR + SI N Y P TE
Sbjct: 343 TWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESI-ANIQIGFMTYLVEPLFTE 401
Query: 738 WNRFLDSKLSXEMXANXXYNEVQWE 812
W RF +++LS M + N+ W+
Sbjct: 402 WARFSNTRLSQTMLGHVGLNKASWK 426
>EF108327-1|ABL14249.1| 502|Homo sapiens phosphodiesterase PDE7B2
protein.
Length = 502
Score = 246 bits (603), Expect = 6e-65
Identities = 118/271 (43%), Positives = 175/271 (64%), Gaps = 2/271 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + +F+ P++I+ LL+A AHD+
Sbjct: 209 RFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVD 268
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T +HLA+LY +N SVLE+HHWR+ + + ES LL P ++ +
Sbjct: 269 HPGVNQPFLIKTNHHLANLY-------QNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQ 321
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++++ L LI+ATDI RQ+++L+R K L L + + R +LQIALKCADI NPCR
Sbjct: 322 DIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCR 381
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS +VCEEF+RQG+ E+ +L ++ LC++ SIP + Y P E
Sbjct: 382 IWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM-SYIVEPLFRE 440
Query: 738 WNRFL-DSKLSXEMXANXXYNEVQWELLMTK 827
W F +S LS M + +N+ QW+ L+ +
Sbjct: 441 WAHFTGNSTLSENMLGHLAHNKAQWKSLLPR 471
>BC075083-1|AAH75083.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 246 bits (603), Expect = 6e-65
Identities = 118/271 (43%), Positives = 175/271 (64%), Gaps = 2/271 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + +F+ P++I+ LL+A AHD+
Sbjct: 157 RFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVD 216
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T +HLA+LY +N SVLE+HHWR+ + + ES LL P ++ +
Sbjct: 217 HPGVNQPFLIKTNHHLANLY-------QNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQ 269
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++++ L LI+ATDI RQ+++L+R K L L + + R +LQIALKCADI NPCR
Sbjct: 270 DIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCR 329
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS +VCEEF+RQG+ E+ +L ++ LC++ SIP + Y P E
Sbjct: 330 IWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM-SYIVEPLFRE 388
Query: 738 WNRFL-DSKLSXEMXANXXYNEVQWELLMTK 827
W F +S LS M + +N+ QW+ L+ +
Sbjct: 389 WAHFTGNSTLSENMLGHLAHNKAQWKSLLPR 419
>BC075082-1|AAH75082.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 246 bits (603), Expect = 6e-65
Identities = 118/271 (43%), Positives = 175/271 (64%), Gaps = 2/271 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + +F+ P++I+ LL+A AHD+
Sbjct: 157 RFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVD 216
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T +HLA+LY +N SVLE+HHWR+ + + ES LL P ++ +
Sbjct: 217 HPGVNQPFLIKTNHHLANLY-------QNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQ 269
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++++ L LI+ATDI RQ+++L+R K L L + + R +LQIALKCADI NPCR
Sbjct: 270 DIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCR 329
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS +VCEEF+RQG+ E+ +L ++ LC++ SIP + Y P E
Sbjct: 330 IWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM-SYIVEPLFRE 388
Query: 738 WNRFL-DSKLSXEMXANXXYNEVQWELLMTK 827
W F +S LS M + +N+ QW+ L+ +
Sbjct: 389 WAHFTGNSTLSENMLGHLAHNKAQWKSLLPR 419
>AL360178-1|CAH73075.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 246 bits (603), Expect = 6e-65
Identities = 118/271 (43%), Positives = 175/271 (64%), Gaps = 2/271 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + +F+ P++I+ LL+A AHD+
Sbjct: 157 RFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVD 216
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T +HLA+LY +N SVLE+HHWR+ + + ES LL P ++ +
Sbjct: 217 HPGVNQPFLIKTNHHLANLY-------QNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQ 269
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++++ L LI+ATDI RQ+++L+R K L L + + R +LQIALKCADI NPCR
Sbjct: 270 DIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCR 329
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS +VCEEF+RQG+ E+ +L ++ LC++ SIP + Y P E
Sbjct: 330 IWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM-SYIVEPLFRE 388
Query: 738 WNRFL-DSKLSXEMXANXXYNEVQWELLMTK 827
W F +S LS M + +N+ QW+ L+ +
Sbjct: 389 WAHFTGNSTLSENMLGHLAHNKAQWKSLLPR 419
>AL138828-4|CAI95287.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 246 bits (603), Expect = 6e-65
Identities = 118/271 (43%), Positives = 175/271 (64%), Gaps = 2/271 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + +F+ P++I+ LL+A AHD+
Sbjct: 157 RFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVD 216
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T +HLA+LY +N SVLE+HHWR+ + + ES LL P ++ +
Sbjct: 217 HPGVNQPFLIKTNHHLANLY-------QNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQ 269
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++++ L LI+ATDI RQ+++L+R K L L + + R +LQIALKCADI NPCR
Sbjct: 270 DIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCR 329
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS +VCEEF+RQG+ E+ +L ++ LC++ SIP + Y P E
Sbjct: 330 IWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM-SYIVEPLFRE 388
Query: 738 WNRFL-DSKLSXEMXANXXYNEVQWELLMTK 827
W F +S LS M + +N+ QW+ L+ +
Sbjct: 389 WAHFTGNSTLSENMLGHLAHNKAQWKSLLPR 419
>AL133319-1|CAH73332.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 246 bits (603), Expect = 6e-65
Identities = 118/271 (43%), Positives = 175/271 (64%), Gaps = 2/271 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + +F+ P++I+ LL+A AHD+
Sbjct: 157 RFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVD 216
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T +HLA+LY +N SVLE+HHWR+ + + ES LL P ++ +
Sbjct: 217 HPGVNQPFLIKTNHHLANLY-------QNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQ 269
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++++ L LI+ATDI RQ+++L+R K L L + + R +LQIALKCADI NPCR
Sbjct: 270 DIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCR 329
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS +VCEEF+RQG+ E+ +L ++ LC++ SIP + Y P E
Sbjct: 330 IWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM-SYIVEPLFRE 388
Query: 738 WNRFL-DSKLSXEMXANXXYNEVQWELLMTK 827
W F +S LS M + +N+ QW+ L+ +
Sbjct: 389 WAHFTGNSTLSENMLGHLAHNKAQWKSLLPR 419
>AJ251860-1|CAB92441.1| 450|Homo sapiens phosphodiesterase 7B
protein.
Length = 450
Score = 246 bits (603), Expect = 6e-65
Identities = 118/271 (43%), Positives = 175/271 (64%), Gaps = 2/271 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + +F+ P++I+ LL+A AHD+
Sbjct: 157 RFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVD 216
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T +HLA+LY +N SVLE+HHWR+ + + ES LL P ++ +
Sbjct: 217 HPGVNQPFLIKTNHHLANLY-------QNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQ 269
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++++ L LI+ATDI RQ+++L+R K L L + + R +LQIALKCADI NPCR
Sbjct: 270 DIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCR 329
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS +VCEEF+RQG+ E+ +L ++ LC++ SIP + Y P E
Sbjct: 330 IWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM-SYIVEPLFRE 388
Query: 738 WNRFL-DSKLSXEMXANXXYNEVQWELLMTK 827
W F +S LS M + +N+ QW+ L+ +
Sbjct: 389 WAHFTGNSTLSENMLGHLAHNKAQWKSLLPR 419
>AB209990-1|BAE06072.1| 586|Homo sapiens PDE7B variant protein
protein.
Length = 586
Score = 246 bits (603), Expect = 6e-65
Identities = 118/271 (43%), Positives = 175/271 (64%), Gaps = 2/271 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + +F+ P++I+ LL+A AHD+
Sbjct: 293 RFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVD 352
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T +HLA+LY +N SVLE+HHWR+ + + ES LL P ++ +
Sbjct: 353 HPGVNQPFLIKTNHHLANLY-------QNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQ 405
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++++ L LI+ATDI RQ+++L+R K L L + + R +LQIALKCADI NPCR
Sbjct: 406 DIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCR 465
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS +VCEEF+RQG+ E+ +L ++ LC++ SIP + Y P E
Sbjct: 466 IWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM-SYIVEPLFRE 524
Query: 738 WNRFL-DSKLSXEMXANXXYNEVQWELLMTK 827
W F +S LS M + +N+ QW+ L+ +
Sbjct: 525 WAHFTGNSTLSENMLGHLAHNKAQWKSLLPR 555
>AB038040-1|BAA96537.1| 450|Homo sapiens cyclic nucleotide
phosphodiesterase 7B protein.
Length = 450
Score = 246 bits (603), Expect = 6e-65
Identities = 118/271 (43%), Positives = 175/271 (64%), Gaps = 2/271 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + +F+ P++I+ LL+A AHD+
Sbjct: 157 RFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVD 216
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T +HLA+LY +N SVLE+HHWR+ + + ES LL P ++ +
Sbjct: 217 HPGVNQPFLIKTNHHLANLY-------QNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQ 269
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
++++ L LI+ATDI RQ+++L+R K L L + + R +LQIALKCADI NPCR
Sbjct: 270 DIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCR 329
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIPXNTNXLL*IYXSLPXITE 737
W +S++WS +VCEEF+RQG+ E+ +L ++ LC++ SIP + Y P E
Sbjct: 330 IWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFM-SYIVEPLFRE 388
Query: 738 WNRFL-DSKLSXEMXANXXYNEVQWELLMTK 827
W F +S LS M + +N+ QW+ L+ +
Sbjct: 389 WAHFTGNSTLSENMLGHLAHNKAQWKSLLPR 419
>AF332652-1|AAK57640.1| 424|Homo sapiens cAMP-specific cyclic
nucleotide phosphodiesterase PDE7A3 protein.
Length = 424
Score = 229 bits (561), Expect = 7e-60
Identities = 109/221 (49%), Positives = 149/221 (67%), Gaps = 1/221 (0%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + + P +I+ L++A HD+
Sbjct: 196 RFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLD 255
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERP-DLQE 377
HPGVNQ FLI T ++LA LY+ N SVLE+HHWR+A+ + ESGL P + ++
Sbjct: 256 HPGVNQPFLIKTNHYLATLYK-------NTSVLENHHWRSAVGLLRESGLFSHLPLESRQ 308
Query: 378 ELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCR 557
+++ + LI+ATDI+RQ++YLS F+ LD L + HR LVLQ+ALKCADI NPCR
Sbjct: 309 QMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLEDTRHRHLVLQMALKCADICNPCR 368
Query: 558 PWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
W +S++WS KV EEFF QGD EK L V+ LCDR + SI
Sbjct: 369 TWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESI 409
>AF536977-1|AAN10119.1| 687|Homo sapiens cAMP-specific
phosphodiesterase PDE4D8 protein.
Length = 687
Score = 135 bits (327), Expect = 2e-31
Identities = 77/228 (33%), Positives = 128/228 (56%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 326 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 384
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E G+ + Q
Sbjct: 385 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCGIFQNLTKKQR 437
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 438 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 497
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 498 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 545
>U50159-1|AAA97892.1| 673|Homo sapiens cAMP-specific
phoshodiesterase HPDE4D3 variant protein.
Length = 673
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 312 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 370
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 371 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 423
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 424 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 483
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 484 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 531
>U50158-1|AAA97891.1| 507|Homo sapiens cAMP-specific
phosphodiesterase HPDE4D2 variant protein.
Length = 507
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 146 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 204
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 205 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 257
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 258 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 317
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 318 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 365
>U50157-1|AAA97890.1| 585|Homo sapiens cAMP-specific
phosphodiesterase HPDE4D1 variant protein.
Length = 585
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 224 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 282
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 283 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 335
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 336 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 395
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 396 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 443
>L20970-1|AAA03592.1| 673|Homo sapiens phosphodiesterase protein.
Length = 673
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 312 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 370
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 371 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 423
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 424 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 483
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 484 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 531
>L20969-1|AAC00042.1| 809|Homo sapiens cyclic AMP phosphodiesterase
protein.
Length = 809
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 448 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 506
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 507 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 559
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 560 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 619
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 620 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 667
>AY388960-1|AAQ90404.1| 679|Homo sapiens cAMP-specific
phosphodiesterase PDE4D9 protein.
Length = 679
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 318 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 376
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 377 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 429
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 430 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 489
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 490 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 537
>AY245867-1|AAP75761.1| 679|Homo sapiens cAMP-specific
phosphodiesterase variant PDE4D9 protein.
Length = 679
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 318 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 376
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 377 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 429
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 430 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 489
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 490 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 537
>AY245866-1|AAP75760.1| 748|Homo sapiens cAMP-specific
phosphodiesterase variant PDE4D7 protein.
Length = 748
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 387 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 445
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 446 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 498
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 499 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 558
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 559 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 606
>AF536976-1|AAN10118.1| 748|Homo sapiens cAMP-specific
phosphodiesterase PDE4D7 protein.
Length = 748
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 387 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 445
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 446 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 498
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 499 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 558
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 559 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 606
>AF536975-1|AAN10117.1| 518|Homo sapiens cAMP-specific
phosphodiesterase PDE4D6 protein.
Length = 518
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 157 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 215
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 216 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 268
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 269 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 328
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 329 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 376
>AF012074-1|AAC00070.1| 507|Homo sapiens cAMP-specific
phosphodiesterase PDE4D2 protein.
Length = 507
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 146 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 204
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 205 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 257
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 258 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 317
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 318 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 365
>AF012073-1|AAC00069.1| 745|Homo sapiens cAMP-specific
phosphodiesterase PDE4D5 protein.
Length = 745
Score = 133 bits (321), Expect = 9e-31
Identities = 76/228 (33%), Positives = 127/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 384 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 442
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 443 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 495
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 496 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 555
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 556 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 603
>BC075822-1|AAH75822.1| 829|Homo sapiens phosphodiesterase 8A
protein.
Length = 829
Score = 132 bits (318), Expect = 2e-30
Identities = 89/267 (33%), Positives = 145/267 (54%), Gaps = 26/267 (9%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+NPYHNS H+ DV A FL + I+ + P++ +A L++A HD+ HPG
Sbjct: 544 IIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGR 603
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG-----LLE--ERPDL 371
FL + LA LY + +VLESHH AAL+ + +G + + ER D
Sbjct: 604 TNSFLCNAGSELAILYN-------DTAVLESHH--AALAFQLTTGDDKCNIFKNMERNDY 654
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRF----KKLLDT--------------NTLDMRIQE 497
+ L++ + +++AT++T+ +++++F K L T NT+ +R E
Sbjct: 655 RT-LRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTM-LRTPE 712
Query: 498 HRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDST 674
+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV + DR++
Sbjct: 713 NRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTC 772
Query: 675 SIPXNTNXLL*IYXSLPXITEWNRFLD 755
SIP + + Y W+ F+D
Sbjct: 773 SIPKSQISFI-DYFITDMFDAWDAFVD 798
>BC060762-1|AAH60762.1| 829|Homo sapiens phosphodiesterase 8A
protein.
Length = 829
Score = 132 bits (318), Expect = 2e-30
Identities = 89/267 (33%), Positives = 145/267 (54%), Gaps = 26/267 (9%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+NPYHNS H+ DV A FL + I+ + P++ +A L++A HD+ HPG
Sbjct: 544 IIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGR 603
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG-----LLE--ERPDL 371
FL + LA LY + +VLESHH AAL+ + +G + + ER D
Sbjct: 604 TNSFLCNAGSELAILYN-------DTAVLESHH--AALAFQLTTGDDKCNIFKNMERNDY 654
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRF----KKLLDT--------------NTLDMRIQE 497
+ L++ + +++AT++T+ +++++F K L T NT+ +R E
Sbjct: 655 RT-LRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTM-LRTPE 712
Query: 498 HRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDST 674
+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV + DR++
Sbjct: 713 NRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTC 772
Query: 675 SIPXNTNXLL*IYXSLPXITEWNRFLD 755
SIP + + Y W+ F+D
Sbjct: 773 SIPKSQISFI-DYFITDMFDAWDAFVD 798
>BC048317-1|AAH48317.1| 305|Homo sapiens PDE8A protein protein.
Length = 305
Score = 132 bits (318), Expect = 2e-30
Identities = 89/267 (33%), Positives = 145/267 (54%), Gaps = 26/267 (9%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+NPYHNS H+ DV A FL + I+ + P++ +A L++A HD+ HPG
Sbjct: 20 IIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGR 79
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG-----LLE--ERPDL 371
FL + LA LY + +VLESHH AAL+ + +G + + ER D
Sbjct: 80 TNSFLCNAGSELAILYN-------DTAVLESHH--AALAFQLTTGDDKCNIFKNMERNDY 130
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRF----KKLLDT--------------NTLDMRIQE 497
+ L++ + +++AT++T+ +++++F K L T NT+ +R E
Sbjct: 131 RT-LRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTM-LRTPE 188
Query: 498 HRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDST 674
+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV + DR++
Sbjct: 189 NRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTC 248
Query: 675 SIPXNTNXLL*IYXSLPXITEWNRFLD 755
SIP + + Y W+ F+D
Sbjct: 249 SIPKSQISFI-DYFITDMFDAWDAFVD 274
>AF388187-1|AAL18614.1| 582|Homo sapiens cAMP phosphodiesterase
PDE8A5 protein.
Length = 582
Score = 132 bits (318), Expect = 2e-30
Identities = 89/267 (33%), Positives = 145/267 (54%), Gaps = 26/267 (9%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+NPYHNS H+ DV A FL + I+ + P++ +A L++A HD+ HPG
Sbjct: 297 IIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGR 356
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG-----LLE--ERPDL 371
FL + LA LY + +VLESHH AAL+ + +G + + ER D
Sbjct: 357 TNSFLCNAGSELAILYN-------DTAVLESHH--AALAFQLTTGDDKCNIFKNMERNDY 407
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRF----KKLLDT--------------NTLDMRIQE 497
+ L++ + +++AT++T+ +++++F K L T NT+ +R E
Sbjct: 408 RT-LRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTM-LRTPE 465
Query: 498 HRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDST 674
+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV + DR++
Sbjct: 466 NRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTC 525
Query: 675 SIPXNTNXLL*IYXSLPXITEWNRFLD 755
SIP + + Y W+ F+D
Sbjct: 526 SIPKSQISFI-DYFITDMFDAWDAFVD 551
>AF388186-1|AAL18613.1| 582|Homo sapiens cAMP phosphodiesterase
PDE8A4 protein.
Length = 582
Score = 132 bits (318), Expect = 2e-30
Identities = 89/267 (33%), Positives = 145/267 (54%), Gaps = 26/267 (9%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+NPYHNS H+ DV A FL + I+ + P++ +A L++A HD+ HPG
Sbjct: 297 IIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGR 356
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG-----LLE--ERPDL 371
FL + LA LY + +VLESHH AAL+ + +G + + ER D
Sbjct: 357 TNSFLCNAGSELAILYN-------DTAVLESHH--AALAFQLTTGDDKCNIFKNMERNDY 407
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRF----KKLLDT--------------NTLDMRIQE 497
+ L++ + +++AT++T+ +++++F K L T NT+ +R E
Sbjct: 408 RT-LRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTM-LRTPE 465
Query: 498 HRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDST 674
+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV + DR++
Sbjct: 466 NRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTC 525
Query: 675 SIPXNTNXLL*IYXSLPXITEWNRFLD 755
SIP + + Y W+ F+D
Sbjct: 526 SIPKSQISFI-DYFITDMFDAWDAFVD 551
>AF388185-1|AAL18612.1| 449|Homo sapiens cAMP phosphodiesterase
PDE8A3 protein.
Length = 449
Score = 132 bits (318), Expect = 2e-30
Identities = 89/267 (33%), Positives = 145/267 (54%), Gaps = 26/267 (9%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+NPYHNS H+ DV A FL + I+ + P++ +A L++A HD+ HPG
Sbjct: 164 IIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGR 223
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG-----LLE--ERPDL 371
FL + LA LY + +VLESHH AAL+ + +G + + ER D
Sbjct: 224 TNSFLCNAGSELAILYN-------DTAVLESHH--AALAFQLTTGDDKCNIFKNMERNDY 274
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRF----KKLLDT--------------NTLDMRIQE 497
+ L++ + +++AT++T+ +++++F K L T NT+ +R E
Sbjct: 275 RT-LRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTM-LRTPE 332
Query: 498 HRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDST 674
+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV + DR++
Sbjct: 333 NRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTC 392
Query: 675 SIPXNTNXLL*IYXSLPXITEWNRFLD 755
SIP + + Y W+ F+D
Sbjct: 393 SIPKSQISFI-DYFITDMFDAWDAFVD 418
>AF388184-1|AAL18611.1| 783|Homo sapiens cAMP phosphodiesterase
PDE8A2 protein.
Length = 783
Score = 132 bits (318), Expect = 2e-30
Identities = 89/267 (33%), Positives = 145/267 (54%), Gaps = 26/267 (9%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+NPYHNS H+ DV A FL + I+ + P++ +A L++A HD+ HPG
Sbjct: 498 IIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGR 557
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG-----LLE--ERPDL 371
FL + LA LY + +VLESHH AAL+ + +G + + ER D
Sbjct: 558 TNSFLCNAGSELAILYN-------DTAVLESHH--AALAFQLTTGDDKCNIFKNMERNDY 608
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRF----KKLLDT--------------NTLDMRIQE 497
+ L++ + +++AT++T+ +++++F K L T NT+ +R E
Sbjct: 609 RT-LRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTM-LRTPE 666
Query: 498 HRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDST 674
+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV + DR++
Sbjct: 667 NRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTC 726
Query: 675 SIPXNTNXLL*IYXSLPXITEWNRFLD 755
SIP + + Y W+ F+D
Sbjct: 727 SIPKSQISFI-DYFITDMFDAWDAFVD 752
>AF388183-1|AAL18610.1| 829|Homo sapiens cAMP phosphodiesterase
PDE8A1 protein.
Length = 829
Score = 132 bits (318), Expect = 2e-30
Identities = 89/267 (33%), Positives = 145/267 (54%), Gaps = 26/267 (9%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+NPYHNS H+ DV A FL + I+ + P++ +A L++A HD+ HPG
Sbjct: 544 IIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGR 603
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG-----LLE--ERPDL 371
FL + LA LY + +VLESHH AAL+ + +G + + ER D
Sbjct: 604 TNSFLCNAGSELAILYN-------DTAVLESHH--AALAFQLTTGDDKCNIFKNMERNDY 654
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRF----KKLLDT--------------NTLDMRIQE 497
+ L++ + +++AT++T+ +++++F K L T NT+ +R E
Sbjct: 655 RT-LRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTM-LRTPE 712
Query: 498 HRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDST 674
+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV + DR++
Sbjct: 713 NRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTC 772
Query: 675 SIPXNTNXLL*IYXSLPXITEWNRFLD 755
SIP + + Y W+ F+D
Sbjct: 773 SIPKSQISFI-DYFITDMFDAWDAFVD 798
>AF332653-1|AAK57641.1| 829|Homo sapiens cAMP-specific cyclic
nucleotide phosphodiesterase PDE8A1 protein.
Length = 829
Score = 132 bits (318), Expect = 2e-30
Identities = 89/267 (33%), Positives = 145/267 (54%), Gaps = 26/267 (9%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+NPYHNS H+ DV A FL + I+ + P++ +A L++A HD+ HPG
Sbjct: 544 IIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGR 603
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG-----LLE--ERPDL 371
FL + LA LY + +VLESHH AAL+ + +G + + ER D
Sbjct: 604 TNSFLCNAGSELAILYN-------DTAVLESHH--AALAFQLTTGDDKCNIFKNMERNDY 654
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRF----KKLLDT--------------NTLDMRIQE 497
+ L++ + +++AT++T+ +++++F K L T NT+ +R E
Sbjct: 655 RT-LRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTM-LRTPE 712
Query: 498 HRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDST 674
+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV + DR++
Sbjct: 713 NRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTC 772
Query: 675 SIPXNTNXLL*IYXSLPXITEWNRFLD 755
SIP + + Y W+ F+D
Sbjct: 773 SIPKSQISFI-DYFITDMFDAWDAFVD 798
>AF056490-1|AAC39763.1| 713|Homo sapiens cAMP-specific
phosphodiesterase 8A protein.
Length = 713
Score = 132 bits (318), Expect = 2e-30
Identities = 89/267 (33%), Positives = 145/267 (54%), Gaps = 26/267 (9%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E+ YHS+NPYHNS H+ DV A FL + I+ + P++ +A L++A HD+ HPG
Sbjct: 428 IIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGR 487
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG-----LLE--ERPDL 371
FL + LA LY + +VLESHH AAL+ + +G + + ER D
Sbjct: 488 TNSFLCNAGSELAILYN-------DTAVLESHH--AALAFQLTTGDDKCNIFKNMERNDY 538
Query: 372 QEELKKHLKVLIMATDITRQHDYLSRF----KKLLDT--------------NTLDMRIQE 497
+ L++ + +++AT++T+ +++++F K L T NT+ +R E
Sbjct: 539 RT-LRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTM-LRTPE 596
Query: 498 HRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDST 674
+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV + DR++
Sbjct: 597 NRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTC 656
Query: 675 SIPXNTNXLL*IYXSLPXITEWNRFLD 755
SIP + + Y W+ F+D
Sbjct: 657 SIPKSQISFI-DYFITDMFDAWDAFVD 682
>BC036319-1|AAH36319.1| 518|Homo sapiens PDE4D protein protein.
Length = 518
Score = 131 bits (317), Expect = 3e-30
Identities = 76/228 (33%), Positives = 126/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 157 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 215
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 216 PGVFNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 268
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 269 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 328
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFFRQGD E+ + ++ +CD+ + S+
Sbjct: 329 DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV 376
>U02882-1|AAC13745.1| 604|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase protein.
Length = 604
Score = 130 bits (314), Expect = 6e-30
Identities = 75/228 (32%), Positives = 126/228 (55%), Gaps = 9/228 (3%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
L TL E YH+ YHN+IHA DV Q+ H L ++ A +EI+A + ++ HD+ H
Sbjct: 243 LMTL-EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDH 301
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ- 374
PGV+ FLI T + LA +Y + SVLE+HH + E + + Q
Sbjct: 302 PGVSNQFLINTNSELALMY-------NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQR 354
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCA 536
+ L+K + +++ATD+++ + L+ K +++T L + RI VLQ + CA
Sbjct: 355 QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA 414
Query: 537 DISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
D+SNP +P + ++W+ ++ EEFF QGD E+ + ++ +CD+ + S+
Sbjct: 415 DLSNPTKPLQLYRQWTDRIMEEFFPQGDRERERGMEISPMCDKHNASV 462
>U88713-1|AAC51916.1| 700|Homo sapiens phosphodiesterase 4C protein.
Length = 700
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 364 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 423
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 424 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 476
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 477 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 536
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 537 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 581
>U88712-1|AAC51915.1| 606|Homo sapiens phosphodiesterase 4C
protein.
Length = 606
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 270 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 329
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 330 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 382
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 383 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 442
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 443 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 487
>U66348-1|AAB96877.1| 518|Homo sapiens PDE4C-delta54 protein.
Length = 518
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 182 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 241
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 242 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 294
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 295 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 354
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 355 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 399
>U66347-1|AAB96876.1| 426|Homo sapiens PDE4C-426 protein.
Length = 426
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 90 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 149
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 150 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 202
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 203 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 262
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 263 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 307
>U66346-1|AAB96875.1| 791|Homo sapiens PDE4C-791 protein.
Length = 791
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 455 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 514
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 515 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 567
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 568 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 627
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 628 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 672
>BC109068-1|AAI09069.1| 549|Homo sapiens PDE4C protein protein.
Length = 549
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 213 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 272
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 273 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 325
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 326 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 385
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 386 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 430
>BC109067-1|AAI09068.1| 481|Homo sapiens PDE4C protein protein.
Length = 481
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 145 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 204
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 205 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 257
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 258 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 317
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 318 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 362
>AF157816-3|AAD47055.1| 606|Homo sapiens cAMP specific
phosphodiesterase PDE4C2 variant protein.
Length = 606
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 270 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 329
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 330 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 382
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 383 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 442
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 443 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 487
>AF157816-2|AAD47054.1| 680|Homo sapiens cAMP specific
phosphodiesterase PDE4C3 variant protein.
Length = 680
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 344 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 403
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 404 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 456
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 457 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 516
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 517 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 561
>AF157816-1|AAD47053.1| 712|Homo sapiens cAMP specific
phosphodiesterase PDE4C1 variant protein.
Length = 712
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 376 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 435
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 436 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 488
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 489 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 548
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 549 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 593
>AC005759-5|AAC83049.1| 426|Homo sapiens PDE4C-426 protein.
Length = 426
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 90 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 149
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 150 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 202
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 203 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 262
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 263 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 307
>AC005759-3|AAC83051.1| 518|Homo sapiens PDE4C-delta54 protein.
Length = 518
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 182 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 241
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 242 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 294
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 295 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 354
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 355 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 399
>AC005759-1|AAC83050.1| 782|Homo sapiens PDE4C-791 protein.
Length = 782
Score = 128 bits (309), Expect = 3e-29
Identities = 72/225 (32%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 446 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 505
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 506 SNQFLINTNSELALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 558
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 559 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 618
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 619 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 663
>U97584-1|AAC25679.1| 647|Homo sapiens cyclic AMP-specific
phosphodiesterase HSPDE4A1A protein.
Length = 647
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 184 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 243
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 244 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 296
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 297 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 356
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 357 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 399
>U68532-1|AAC63832.1| 647|Homo sapiens cyclic AMP specific
phosphodiesterase RD1 protein.
Length = 647
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 184 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 243
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 244 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 296
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 297 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 356
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 357 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 399
>U18088-1|AAA98540.1| 323|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase HSPDE4A7A protein.
Length = 323
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 89 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 148
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 149 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 201
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 202 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 261
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 262 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 304
>U18087-1|AAC50458.1| 686|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase HPDE4A6 protein.
Length = 686
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 223 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 282
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 283 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 335
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 336 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 395
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 396 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 438
>S75213-1|AAB33798.1| 667|Homo sapiens type-IVA cyclic AMP specific
phosphodiesterase protein.
Length = 667
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 204 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 263
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 264 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 316
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 317 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 376
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 377 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 419
>M37744-1|AAA69697.1| 775|Homo sapiens protein ( Human cyclic AMP
(cAMP)-specific phosphodiesterase mRNA, complete cds. ).
Length = 775
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 312 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 371
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 372 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 424
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 425 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 484
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 485 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 527
>L20965-1|AAA03588.1| 886|Homo sapiens phosphodiesterase protein.
Length = 886
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 423 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 482
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 483 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 535
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 536 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 595
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 596 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 638
>BC038234-1|AAH38234.1| 647|Homo sapiens phosphodiesterase 4A,
cAMP-specific (phosphodiesterase E2 dunce homolog,
Drosop protein.
Length = 647
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 184 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 243
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 244 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 296
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 297 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 356
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 357 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 399
>BC019864-1|AAH19864.1| 647|Homo sapiens phosphodiesterase 4A,
cAMP-specific (phosphodiesterase E2 dunce homolog,
Drosop protein.
Length = 647
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 184 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 243
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 244 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 296
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 297 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 356
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 357 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 399
>AY618547-1|AAU82096.1| 860|Homo sapiens cyclic AMP phosphodiesterase
PDE4A11 protein.
Length = 860
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 397 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 456
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 457 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 509
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 510 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 569
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 570 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 612
>AY593872-1|AAT00628.1| 864|Homo sapiens cAMP-specific
phosphodiesterase protein.
Length = 864
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 401 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 460
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 461 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 513
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 514 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 573
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 574 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 616
>AF073745-1|AAD34217.2| 825|Homo sapiens cyclic AMP-specific
phosphodiesterase HSPDE4A10 protein.
Length = 825
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 362 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 421
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 422 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 474
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 475 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 534
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 535 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 577
>AF069491-4|AAC35014.1| 323|Homo sapiens cAMP specific
phosphodiesterase 4A variant 2EL protein.
Length = 323
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 89 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 148
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 149 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 201
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 202 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 261
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 262 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 304
>AF069491-3|AAC35013.1| 647|Homo sapiens cAMP specific
phosphodiesterase 4A variant RD1 protein.
Length = 647
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 184 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 243
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 244 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 296
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 297 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 356
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 357 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 399
>AF069491-2|AAC35015.1| 860|Homo sapiens putative novel cAMP specific
phosphodiesterase 4A variant protein.
Length = 860
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 397 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 456
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 457 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 509
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 510 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 569
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 570 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 612
>AF069491-1|AAC35012.1| 886|Homo sapiens cAMP specific
phosphodiesterase 4A variant pde46 protein.
Length = 886
Score = 127 bits (306), Expect = 6e-29
Identities = 72/223 (32%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L +A HD+ HPGV+
Sbjct: 423 EDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSN 482
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKK 389
FLI T + LA +Y + SVLE+HH + E + + Q + L+K
Sbjct: 483 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK 535
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 536 MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNP 595
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+P + ++W+ ++ EFF+QGD E+ + ++ +CD+ + S+
Sbjct: 596 TKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV 638
>Z46632-1|CAA86601.1| 712|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase protein.
Length = 712
Score = 126 bits (305), Expect = 8e-29
Identities = 71/225 (31%), Positives = 127/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 376 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 435
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T + +A +Y + SVLE+HH + E+ + + ++ L
Sbjct: 436 SNQFLINTNSDVALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 488
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 489 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 548
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 549 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 593
>U85048-1|AAB96381.1| 721|Homo sapiens cyclic AMP specific
phosphodiesterase protein.
Length = 721
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 381 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 440
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 441 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 493
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 494 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 553
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 554 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 596
>M97515-1|AAA36426.1| 564|Homo sapiens phosphodiesterase protein.
Length = 564
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 224 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 283
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 284 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 336
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 337 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 396
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 397 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 439
>L20971-1|AAA03593.1| 564|Homo sapiens phosphodiesterase protein.
Length = 564
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 224 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 283
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 284 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 336
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 337 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 396
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 397 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 439
>L20966-1|AAA03589.1| 736|Homo sapiens phosphodiesterase protein.
Length = 736
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 396 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 455
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 456 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 508
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 509 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 568
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 569 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 611
>L12686-1|AAA35643.1| 606|Homo sapiens 3',5'-cyclic AMP
phosphodiesterase protein.
Length = 606
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 266 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 325
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 326 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 378
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 379 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 438
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 439 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 481
>EF595686-1|ABQ85407.1| 503|Homo sapiens cAMP-specific
phosphodiesterase-4 B isoform protein.
Length = 503
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 163 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 222
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 223 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 275
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 276 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 335
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 336 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 378
>BC105040-1|AAI05041.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 396 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 455
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 456 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 508
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 509 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 568
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 569 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 611
>BC101480-1|AAI01481.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 396 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 455
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 456 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 508
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 509 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 568
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 569 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 611
>AL592285-3|CAH70628.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 721
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 381 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 440
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 441 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 493
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 494 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 553
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 554 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 596
>AL592285-1|CAH70626.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 396 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 455
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 456 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 508
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 509 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 568
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 569 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 611
>AL359701-3|CAI23101.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 721
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 381 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 440
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 441 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 493
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 494 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 553
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 554 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 596
>AL359701-2|CAI23100.1| 564|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 564
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 224 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 283
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 284 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 336
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 337 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 396
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 397 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 439
>AL359701-1|CAI23099.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 396 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 455
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 456 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 508
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 509 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 568
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 569 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 611
>AL357273-3|CAH73004.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 721
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 381 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 440
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 441 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 493
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 494 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 553
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 554 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 596
>AL357273-1|CAH73002.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 396 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 455
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 456 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 508
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 509 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 568
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 569 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 611
>AL109926-4|CAI21751.1| 721|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 721
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 381 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 440
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 441 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 493
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 494 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 553
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 554 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 596
>AL109926-3|CAI21750.1| 564|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog,
Drosop protein.
Length = 564
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 224 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 283
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 284 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 336
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 337 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 396
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 397 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 439
>AL109926-2|CAI21749.1| 736|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 736
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 396 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 455
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 456 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 508
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 509 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 568
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 569 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 611
>AB209081-1|BAD92318.1| 726|Homo sapiens phosphodiesterase 4B,
cAMP-specific (phosphodiesterase E4 dunce homolog, Drosop
protein.
Length = 726
Score = 126 bits (303), Expect = 1e-28
Identities = 71/223 (31%), Positives = 121/223 (54%), Gaps = 9/223 (4%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
E YHS YHNS+HA DV Q+ H L ++ A +EI+A + +A HD+ HPGV+
Sbjct: 386 EDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSN 445
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKK 389
FLI T + LA +Y + SVLE+HH + E + ++ L+K
Sbjct: 446 QFLINTNSELALMY-------NDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRK 498
Query: 390 HLKVLIMATDITRQHDYLSRFKKLLDT------NTLDMRIQEHRILVLQIALKCADISNP 551
+ +++ATD+++ L+ K +++T L + RI VL+ + CAD+SNP
Sbjct: 499 MVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNP 558
Query: 552 CRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ + ++W+ ++ EEFF+QGD E+ + ++ +CD+ + S+
Sbjct: 559 TKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASV 601
>AY423729-1|AAS00492.1| 350|Homo sapiens proliferation-inducing
gene 22 protein protein.
Length = 350
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 66 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 125
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 126 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 178
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 179 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 238
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 239 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 295
>AY129950-3|AAN71727.1| 788|Homo sapiens cAMP-specific
phosphodiesterase 8B3 protein.
Length = 788
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 504 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 563
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 564 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 616
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 617 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 676
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 677 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 733
>AY129950-2|AAN71726.1| 838|Homo sapiens cAMP-specific
phosphodiesterase 8B2 protein.
Length = 838
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 554 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 613
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 614 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 666
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 667 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 726
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 727 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 783
>AY129950-1|AAN71725.1| 885|Homo sapiens cAMP-specific
phosphodiesterase 8B1 protein.
Length = 885
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 601 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 660
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 661 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 713
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 714 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 773
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 774 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 830
>AY129949-1|AAN71724.1| 788|Homo sapiens cAMP-specific
phosphodiesterase 8B3 protein.
Length = 788
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 504 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 563
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 564 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 616
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 617 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 676
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 677 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 733
>AY129948-1|AAN71723.1| 838|Homo sapiens cAMP-specific
phosphodiesterase 8B2 protein.
Length = 838
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 554 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 613
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 614 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 666
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 667 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 726
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 727 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 783
>AL831924-1|CAD38584.1| 843|Homo sapiens hypothetical protein
protein.
Length = 843
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 559 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 618
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 619 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 671
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 672 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 731
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 732 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 788
>AF079529-1|AAC69564.2| 885|Homo sapiens cAMP-specific
phosphodiesterase 8B1 protein.
Length = 885
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 601 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 660
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 661 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 713
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 714 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 773
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 774 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 830
>AB085827-1|BAC53765.1| 865|Homo sapiens phosphodiesterase 8B4
protein.
Length = 865
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 581 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 640
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 641 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 693
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 694 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 753
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 754 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 810
>AB085826-1|BAC53764.1| 830|Homo sapiens phosphodiesterase 8B3
protein.
Length = 830
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 546 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 605
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 606 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 658
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 659 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 718
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 719 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 775
>AB085825-1|BAC53763.1| 788|Homo sapiens phosphodiestearse 8B2
protein.
Length = 788
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 504 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 563
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 564 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 616
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 617 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 676
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 677 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 733
>AB085824-1|BAC53762.1| 885|Homo sapiens phosphodiesterase 8B1
protein.
Length = 885
Score = 124 bits (299), Expect = 4e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 601 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 660
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 661 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 713
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 714 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIK 773
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 774 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 830
>U86078-1|AAC51872.1| 536|Homo sapiens calmodulin-stimulated
phosphodiesterase PDE1B1 protein.
Length = 536
Score = 124 bits (298), Expect = 5e-28
Identities = 77/218 (35%), Positives = 115/218 (52%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E+GY NPYHN IHA DVTQ +HCFLL+ + + +E++A + +A HD H G
Sbjct: 212 ETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTT 271
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL---LEERPDLQEELK 386
F I T + A +Y + SVLE+HH + + + + + D EL+
Sbjct: 272 NSFHIQTKSECAIVY-------NDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELR 324
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ +++ATD++ + K L L+ RI + + L + L ADIS+P + W
Sbjct: 325 ALVIEMVLATDMSCHFQQVKTMKTAL--QQLE-RIDKPK--ALSLLLHAADISHPTKQWL 379
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
V +W+ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 380 VHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLV 417
>U56976-1|AAC50769.1| 536|Homo sapiens calmodulin dependent
phosphodiesterase PDE1B1 protein.
Length = 536
Score = 124 bits (298), Expect = 5e-28
Identities = 77/218 (35%), Positives = 115/218 (52%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E+GY NPYHN IHA DVTQ +HCFLL+ + + +E++A + +A HD H G
Sbjct: 212 ETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTT 271
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL---LEERPDLQEELK 386
F I T + A +Y + SVLE+HH + + + + + D EL+
Sbjct: 272 NSFHIQTKSECAIVY-------NDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELR 324
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ +++ATD++ + K L L+ RI + + L + L ADIS+P + W
Sbjct: 325 ALVIEMVLATDMSCHFQQVKTMKTAL--QQLE-RIDKPK--ALSLLLHAADISHPTKQWL 379
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
V +W+ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 380 VHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLV 417
>BX538092-1|CAD98011.1| 399|Homo sapiens hypothetical protein
protein.
Length = 399
Score = 124 bits (298), Expect = 5e-28
Identities = 77/218 (35%), Positives = 115/218 (52%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E+GY NPYHN IHA DVTQ +HCFLL+ + + +E++A + +A HD H G
Sbjct: 75 ETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTT 134
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL---LEERPDLQEELK 386
F I T + A +Y + SVLE+HH + + + + + D EL+
Sbjct: 135 NSFHIQTKSECAIVY-------NDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELR 187
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ +++ATD++ + K L L+ RI + + L + L ADIS+P + W
Sbjct: 188 ALVIEMVLATDMSCHFQQVKTMKTAL--QQLE-RIDKPK--ALSLLLHAADISHPTKQWL 242
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
V +W+ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 243 VHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLV 280
>BC035144-1|AAH35144.1| 385|Homo sapiens PDE8B protein protein.
Length = 385
Score = 124 bits (298), Expect = 5e-28
Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 18/237 (7%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHP 206
F + E+ YHS+N YHNS HA DV A FL + ++ + ++ +A L++A HD+ HP
Sbjct: 101 FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP 160
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEE-- 380
G FL + LA LY + +VLESHH A ++ ++
Sbjct: 161 GRTNSFLCNAGSELAVLY-------NDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHY 213
Query: 381 --LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DTNTLDMRIQEHRILVL 515
L++ + +++AT++T+ +++++F + + N E++IL+
Sbjct: 214 RTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFLENQILIK 273
Query: 516 QIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQ-LCDRDSTSIP 683
++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV + DR++ SIP
Sbjct: 274 RMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIP 330
>BC032226-1|AAH32226.1| 536|Homo sapiens phosphodiesterase 1B,
calmodulin-dependent protein.
Length = 536
Score = 124 bits (298), Expect = 5e-28
Identities = 77/218 (35%), Positives = 115/218 (52%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E+GY NPYHN IHA DVTQ +HCFLL+ + + +E++A + +A HD H G
Sbjct: 212 ETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTT 271
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL---LEERPDLQEELK 386
F I T + A +Y + SVLE+HH + + + + + D EL+
Sbjct: 272 NSFHIQTKSECAIVY-------NDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELR 324
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ +++ATD++ + K L L+ RI + + L + L ADIS+P + W
Sbjct: 325 ALVIEMVLATDMSCHFQQVKTMKTAL--QQLE-RIDKPK--ALSLLLHAADISHPTKQWL 379
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
V +W+ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 380 VHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLV 417
>AJ401609-1|CAC82207.1| 516|Homo sapiens 3'5' cyclic nucleotide
phosphodiesterase 1B2 protein.
Length = 516
Score = 124 bits (298), Expect = 5e-28
Identities = 77/218 (35%), Positives = 115/218 (52%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E+GY NPYHN IHA DVTQ +HCFLL+ + + +E++A + +A HD H G
Sbjct: 192 ETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTT 251
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL---LEERPDLQEELK 386
F I T + A +Y + SVLE+HH + + + + + D EL+
Sbjct: 252 NSFHIQTKSECAIVY-------NDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELR 304
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ +++ATD++ + K L L+ RI + + L + L ADIS+P + W
Sbjct: 305 ALVIEMVLATDMSCHFQQVKTMKTAL--QQLE-RIDKPK--ALSLLLHAADISHPTKQWL 359
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
V +W+ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 360 VHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLV 397
>AC005759-2|AAC83047.1| 710|Homo sapiens CN4C_HUMAN protein.
Length = 710
Score = 123 bits (297), Expect = 7e-28
Identities = 72/225 (32%), Positives = 126/225 (56%), Gaps = 9/225 (4%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGV 212
+ E YH+ YHNS+HA DV Q+ H L ++ A +EI+A L ++ HD+ HPGV
Sbjct: 376 MLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGV 435
Query: 213 NQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCI-IESGLLEERPDLQEELKK 389
+ FLI T LA +Y + SVLE+HH + E+ + + ++ L
Sbjct: 436 SNQFLINT--KLALMY-------NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSL 486
Query: 390 HLKV--LIMATDITRQHDYLSRFKKLLDT---NTLDMRIQEH---RILVLQIALKCADIS 545
V +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+S
Sbjct: 487 RRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLS 546
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
NP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 547 NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 591
>U40370-1|AAC50436.1| 535|Homo sapiens 3',5' cyclic nucleotide
phosphodiesterase protein.
Length = 535
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 208 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 267
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 268 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 320
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 321 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 375
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 376 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 413
>BC022480-1|AAH22480.1| 545|Homo sapiens phosphodiesterase 1A,
calmodulin-dependent protein.
Length = 545
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 208 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 267
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 268 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 320
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 321 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 375
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 376 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 413
>AL110263-1|CAB53703.1| 519|Homo sapiens hypothetical protein
protein.
Length = 519
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 192 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 251
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 252 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 304
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 305 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 359
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 360 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 397
>AJ401610-1|CAC82208.1| 519|Homo sapiens 3'5' cyclic nucleotide
phosphodiesterase 1A5 protein.
Length = 519
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 192 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 251
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 252 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 304
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 305 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 359
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 360 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 397
>AB038224-9|BAB20054.1| 518|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 518
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 174 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 233
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 234 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 286
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 287 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 341
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 342 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 379
>AB038224-8|BAB20053.1| 501|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 501
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 174 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 233
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 234 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 286
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 287 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 341
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 342 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 379
>AB038224-7|BAB20057.1| 511|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 511
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 174 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 233
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 234 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 286
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 287 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 341
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 342 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 379
>AB038224-6|BAB20052.1| 552|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 552
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 208 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 267
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 268 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 320
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 321 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 375
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 376 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 413
>AB038224-5|BAB20050.1| 535|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 535
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 208 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 267
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 268 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 320
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 321 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 375
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 376 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 413
>AB038224-4|BAB20056.1| 545|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 545
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 208 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 267
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 268 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 320
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 321 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 375
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 376 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 413
>AB038224-3|BAB20051.1| 536|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 536
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 192 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 251
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 252 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 304
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 305 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 359
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 360 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 397
>AB038224-2|BAB20049.1| 519|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 519
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 192 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 251
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 252 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 304
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 305 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 359
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 360 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 397
>AB038224-1|BAB20055.1| 529|Homo sapiens calmodulin-dependent
phosphodiesterase protein.
Length = 529
Score = 120 bits (290), Expect = 5e-27
Identities = 74/218 (33%), Positives = 111/218 (50%), Gaps = 4/218 (1%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN IHA DVTQ +H +L I ++ +EI+A + +A HD H G
Sbjct: 192 EVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTT 251
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELK 386
F I T + +A LY + SVLE+HH AA + E L+ D +L+
Sbjct: 252 NNFHIQTRSDVAILY-------NDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLR 304
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ ++++TD++ + + N+L R + + L ADIS+P + W
Sbjct: 305 NLVIEMVLSTDMSGHFQQIKNIR-----NSLQQPEGIDRAKTMSLILHAADISHPAKSWK 359
Query: 567 VSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFF QGD E L LP + LCDR ST +
Sbjct: 360 LHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMV 397
>U40372-1|AAA96961.1| 564|Homo sapiens PDE1C3 protein.
Length = 564
Score = 119 bits (287), Expect = 1e-26
Identities = 77/219 (35%), Positives = 110/219 (50%), Gaps = 5/219 (2%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN +HA DVTQ +H L + + ++ +EI A + SA HD H G
Sbjct: 72 EVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTT 131
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG----LLEERPDLQEEL 383
F I T + A LY + SVLE+HH AA + + L+ D E
Sbjct: 132 NNFHIQTRSDPAILYN-------DRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREF 184
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
+ + ++MATD++ + K L I++ + L L L ADIS+P + W
Sbjct: 185 RTLVIEMVMATDMSCHFQQIKAMKTALQQPEA---IEKPKALSLM--LHTADISHPAKAW 239
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 240 DLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMV 278
>U40371-1|AAC50437.1| 634|Homo sapiens 3',5' cyclic nucleotide
phosphodiesterase protein.
Length = 634
Score = 119 bits (287), Expect = 1e-26
Identities = 77/219 (35%), Positives = 110/219 (50%), Gaps = 5/219 (2%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN +HA DVTQ +H L + + ++ +EI A + SA HD H G
Sbjct: 217 EVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTT 276
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG----LLEERPDLQEEL 383
F I T + A LY + SVLE+HH AA + + L+ D E
Sbjct: 277 NNFHIQTRSDPAILYN-------DRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREF 329
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
+ + ++MATD++ + K L I++ + L L L ADIS+P + W
Sbjct: 330 RTLVIEMVMATDMSCHFQQIKAMKTALQQPEA---IEKPKALSLM--LHTADISHPAKAW 384
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 385 DLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMV 423
>BC022525-1|AAH22525.1| 634|Homo sapiens PDE1C protein protein.
Length = 634
Score = 119 bits (287), Expect = 1e-26
Identities = 77/219 (35%), Positives = 110/219 (50%), Gaps = 5/219 (2%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN +HA DVTQ +H L + + ++ +EI A + SA HD H G
Sbjct: 217 EVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTT 276
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG----LLEERPDLQEEL 383
F I T + A LY + SVLE+HH AA + + L+ D E
Sbjct: 277 NNFHIQTRSDPAILYN-------DRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREF 329
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
+ + ++MATD++ + K L I++ + L L L ADIS+P + W
Sbjct: 330 RTLVIEMVMATDMSCHFQQIKAMKTALQQPEA---IEKPKALSLM--LHTADISHPAKAW 384
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 385 DLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMV 423
>BC022479-1|AAH22479.1| 634|Homo sapiens PDE1C protein protein.
Length = 634
Score = 119 bits (287), Expect = 1e-26
Identities = 77/219 (35%), Positives = 110/219 (50%), Gaps = 5/219 (2%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN +HA DVTQ +H L + + ++ +EI A + SA HD H G
Sbjct: 217 EVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTT 276
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG----LLEERPDLQEEL 383
F I T + A LY + SVLE+HH AA + + L+ D E
Sbjct: 277 NNFHIQTRSDPAILYN-------DRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREF 329
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
+ + ++MATD++ + K L I++ + L L L ADIS+P + W
Sbjct: 330 RTLVIEMVMATDMSCHFQQIKAMKTALQQPEA---IEKPKALSLM--LHTADISHPAKAW 384
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 385 DLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMV 423
>AK091734-1|BAC03734.1| 769|Homo sapiens (EC 3.1.4.17). protein.
Length = 769
Score = 119 bits (287), Expect = 1e-26
Identities = 77/219 (35%), Positives = 110/219 (50%), Gaps = 5/219 (2%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN +HA DVTQ +H L + + ++ +EI A + SA HD H G
Sbjct: 277 EVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTT 336
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG----LLEERPDLQEEL 383
F I T + A LY + SVLE+HH AA + + L+ D E
Sbjct: 337 NNFHIQTRSDPAILYN-------DRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREF 389
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
+ + ++MATD++ + K L I++ + L L L ADIS+P + W
Sbjct: 390 RTLVIEMVMATDMSCHFQQIKAMKTALQQPEA---IEKPKALSLM--LHTADISHPAKAW 444
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 445 DLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMV 483
>AC006377-1|AAS07516.1| 591|Homo sapiens unknown protein.
Length = 591
Score = 119 bits (287), Expect = 1e-26
Identities = 77/219 (35%), Positives = 110/219 (50%), Gaps = 5/219 (2%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E GY NPYHN +HA DVTQ +H L + + ++ +EI A + SA HD H G
Sbjct: 174 EVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTT 233
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG----LLEERPDLQEEL 383
F I T + A LY + SVLE+HH AA + + L+ D E
Sbjct: 234 NNFHIQTRSDPAILYN-------DRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREF 286
Query: 384 KKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPW 563
+ + ++MATD++ + K L I++ + L L L ADIS+P + W
Sbjct: 287 RTLVIEMVMATDMSCHFQQIKAMKTALQQPEA---IEKPKALSLM--LHTADISHPAKAW 341
Query: 564 SVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
+ +W++ + EEFFRQGD E L LP + LCDR ST +
Sbjct: 342 DLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMV 380
>BT007016-1|AAP35662.1| 533|Homo sapiens phosphodiesterase 9A
protein.
Length = 533
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 246 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 305
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 306 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 358
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 359 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 416
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 417 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 448
>BC009047-1|AAH09047.1| 533|Homo sapiens phosphodiesterase 9A
protein.
Length = 533
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 246 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 305
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 306 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 358
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 359 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 416
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 417 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 448
>AY701187-1|AAV84271.1| 485|Homo sapiens phosphodiesterase PDE9A21
protein.
Length = 485
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 198 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 257
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 258 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 310
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 311 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 368
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 369 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 400
>AY242121-1|AAO88210.1| 492|Homo sapiens type 9 cGMP-specific
phosphodiesterase isoform 5 protein.
Length = 492
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 205 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 264
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 265 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 317
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 318 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 375
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 376 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 407
>AY196314-1|AAO34700.1| 386|Homo sapiens phosphodiesterase PDE9A20
protein.
Length = 386
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 99 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 158
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 159 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 211
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 212 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 269
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 270 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 301
>AY196313-1|AAO34699.1| 386|Homo sapiens phosphodiesterase PDE9A19
protein.
Length = 386
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 99 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 158
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 159 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 211
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 212 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 269
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 270 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 301
>AY196312-1|AAO34698.1| 567|Homo sapiens phosphodiesterase PDE9A18
protein.
Length = 567
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 280 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 339
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 340 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 392
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 393 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 450
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 451 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 482
>AY196311-1|AAO34697.1| 552|Homo sapiens phosphodiesterase PDE9A17
protein.
Length = 552
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 265 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 324
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 325 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 377
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 378 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 435
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 436 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 467
>AY196310-1|AAO34696.1| 526|Homo sapiens phosphodiesterase PDE9A16
protein.
Length = 526
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 239 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 298
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 299 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 351
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 352 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 409
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 410 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 441
>AY196309-1|AAO34695.1| 376|Homo sapiens phosphodiesterase PDE9A15
protein.
Length = 376
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 89 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 148
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 149 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 201
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 202 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 259
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 260 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 291
>AY196308-1|AAO34694.1| 386|Homo sapiens phosphodiesterase PDE9A14
protein.
Length = 386
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 99 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 158
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 159 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 211
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 212 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 269
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 270 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 301
>AY196307-1|AAO34693.1| 491|Homo sapiens phosphodiesterase PDE9A13
protein.
Length = 491
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 204 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 263
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 264 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 316
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 317 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 374
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 375 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 406
>AY196306-1|AAO34692.1| 459|Homo sapiens phosphodiesterase PDE9A12
protein.
Length = 459
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 172 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 231
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 232 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 284
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 285 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 342
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 343 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 374
>AY196305-1|AAO34691.1| 376|Homo sapiens phosphodiesterase PDE9A11
protein.
Length = 376
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 89 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 148
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 149 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 201
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 202 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 259
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 260 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 291
>AY196304-1|AAO34690.1| 433|Homo sapiens phosphodiesterase PDE9A10
protein.
Length = 433
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 146 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 205
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 206 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 258
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 259 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 316
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 317 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 348
>AY196303-1|AAO34689.1| 507|Homo sapiens phosphodiesterase PDE9A9
protein.
Length = 507
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 220 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 279
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 280 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 332
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 333 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 390
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 391 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 422
>AY196302-1|AAO34688.1| 386|Homo sapiens phosphodiesterase PDE9A8
protein.
Length = 386
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 99 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 158
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 159 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 211
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 212 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 269
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 270 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 301
>AY196301-1|AAO34687.1| 386|Homo sapiens phosphodiesterase PDE9A7
protein.
Length = 386
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 99 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 158
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 159 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 211
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 212 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 269
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 270 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 301
>AY196300-1|AAO34686.1| 492|Homo sapiens phosphodiesterase PDE9A6
protein.
Length = 492
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 205 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 264
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 265 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 317
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 318 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 375
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 376 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 407
>AY196299-1|AAO34685.1| 540|Homo sapiens phosphodiesterase PDE9A5
protein.
Length = 540
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 253 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 312
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 313 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 365
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 366 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 423
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 424 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 455
>AP001747-1|BAA95552.1| 593|Homo sapiens CGMP-specific 3',5'-cyclic
phosphodiesterase type 9, EC 3.1.4.17. protein.
Length = 593
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 306 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 365
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 366 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 418
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 419 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 476
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 477 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 508
>AF067226-1|AAC26726.1| 465|Homo sapiens cGMP phosphodiesterase A4
protein.
Length = 465
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 178 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 237
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 238 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 290
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 291 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 348
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 349 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 380
>AF067225-1|AAC26725.1| 466|Homo sapiens cGMP phosphodiesterase A3
protein.
Length = 466
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 179 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 238
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 239 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 291
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 292 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 349
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 350 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 381
>AF067224-1|AAC26724.1| 533|Homo sapiens cGMP phosphodiesterase A2
protein.
Length = 533
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 246 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 305
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 306 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 358
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 359 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 416
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 417 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 448
>AF067223-1|AAC26723.1| 593|Homo sapiens cGMP phosphodiesterase A1
protein.
Length = 593
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 306 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 365
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 366 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 418
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 419 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 476
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 477 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 508
>AF048837-1|AAC39778.1| 593|Homo sapiens cGMP-specific
phosphodiesterase protein.
Length = 593
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 306 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 365
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 366 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 418
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 419 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 476
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 477 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 508
>AB017602-1|BAA88847.1| 593|Homo sapiens cGMP phosphodiesterase
protein.
Length = 593
Score = 111 bits (268), Expect = 2e-24
Identities = 67/212 (31%), Positives = 103/212 (48%), Gaps = 3/212 (1%)
Frame = +3
Query: 51 HSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLI 230
+ NP+HN H V Q M+ + S++ +I+ + +AI HD+ HPG N + I
Sbjct: 306 YRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQI 365
Query: 231 ATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKV 401
LA Y + S LE+HH A + E PD +++++ +
Sbjct: 366 NARTELAVRYN-------DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMIT 418
Query: 402 LIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKW 581
LI+ATD+ R + + FK+ ++ D +EH L+ I +KC DISN RP V++ W
Sbjct: 419 LILATDMARHAEIMDSFKEKMEN--FDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPW 476
Query: 582 SVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTS 677
+ EE+F Q D EK LPV DRD +
Sbjct: 477 VDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT 508
>AL138828-3|CAI95286.1| 199|Homo sapiens phosphodiesterase 7B
protein.
Length = 199
Score = 109 bits (261), Expect = 2e-23
Identities = 49/107 (45%), Positives = 72/107 (67%)
Frame = +3
Query: 21 KLFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIF 200
+ + + YHS NPYHN++HA DVTQAMHC+L + + +F+ P++I+ LL+A AHD+
Sbjct: 51 RFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVD 110
Query: 201 HPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIE 341
HPGVNQ FLI T +HLA+LY++ E E +V W AL +++
Sbjct: 111 HPGVNQPFLIKTNHHLANLYQVREPNLEPATV-----WSIALGPVLK 152
>U67733-1|AAC51320.1| 941|Homo sapiens PDE2A3 protein.
Length = 941
Score = 97.9 bits (233), Expect = 4e-20
Identities = 65/223 (29%), Positives = 111/223 (49%), Gaps = 6/223 (2%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRA--FIRPVEIIACLLSAIAHDIFHP 206
+ + GY PYHN +HA V+ C+LL ++ ++ +EI A +S + HD+ H
Sbjct: 645 MVKKGYRDP-PYHNWMHAFSVSH--FCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHR 701
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLE--ERPDLQ 374
G N F +A+ + LA LY S SV+E HH+ A++ + G + + R D Q
Sbjct: 702 GTNNSFQVASKSVLAALY------SSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQ 755
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPC 554
L ++ +I+ATD+ +K+ + Q HR+L+ + C D+S+
Sbjct: 756 RMLDL-MRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSC-DLSDQT 813
Query: 555 RPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+ W ++K + + +EFF QGD EK + ++ DR+ IP
Sbjct: 814 KGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIP 856
>BC040974-1|AAH40974.1| 941|Homo sapiens phosphodiesterase 2A,
cGMP-stimulated protein.
Length = 941
Score = 97.9 bits (233), Expect = 4e-20
Identities = 65/223 (29%), Positives = 111/223 (49%), Gaps = 6/223 (2%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRA--FIRPVEIIACLLSAIAHDIFHP 206
+ + GY PYHN +HA V+ C+LL ++ ++ +EI A +S + HD+ H
Sbjct: 645 MVKKGYRDP-PYHNWMHAFSVSH--FCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHR 701
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLE--ERPDLQ 374
G N F +A+ + LA LY S SV+E HH+ A++ + G + + R D Q
Sbjct: 702 GTNNSFQVASKSVLAALY------SSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQ 755
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPC 554
L ++ +I+ATD+ +K+ + Q HR+L+ + C D+S+
Sbjct: 756 RMLDL-MRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSC-DLSDQT 813
Query: 555 RPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+ W ++K + + +EFF QGD EK + ++ DR+ IP
Sbjct: 814 KGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIP 856
>AK131525-1|BAD18664.1| 685|Homo sapiens protein ( Homo sapiens cDNA
FLJ16750 fis, clone ADRGL2011190, highly similar to
cGMP-dependent 3',5'-cyclic phosphodiesterase (EC
3.1.4.17). ).
Length = 685
Score = 97.9 bits (233), Expect = 4e-20
Identities = 65/223 (29%), Positives = 111/223 (49%), Gaps = 6/223 (2%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRA--FIRPVEIIACLLSAIAHDIFHP 206
+ + GY PYHN +HA V+ C+LL ++ ++ +EI A +S + HD+ H
Sbjct: 389 MVKKGYRDP-PYHNWMHAFSVSH--FCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHR 445
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLE--ERPDLQ 374
G N F +A+ + LA LY S SV+E HH+ A++ + G + + R D Q
Sbjct: 446 GTNNSFQVASKSVLAALY------SSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQ 499
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPC 554
L ++ +I+ATD+ +K+ + Q HR+L+ + C D+S+
Sbjct: 500 RMLDL-MRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSC-DLSDQT 557
Query: 555 RPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+ W ++K + + +EFF QGD EK + ++ DR+ IP
Sbjct: 558 KGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIP 600
>BC114431-1|AAI14432.1| 934|Homo sapiens phosphodiesterase 11A
protein.
Length = 934
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 663 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 722
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 723 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 775
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 776 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 835
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 836 SEFFEQGDRERLELKLTPSAIFDRN 860
>BC112393-1|AAI12394.1| 934|Homo sapiens phosphodiesterase 11A
protein.
Length = 934
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 663 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 722
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 723 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 775
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 776 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 835
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 836 SEFFEQGDRERLELKLTPSAIFDRN 860
>AJ278682-1|CAC15567.1| 684|Homo sapiens cAMP/cGMP cyclic nucleotide
phosphodiesterase 11A3 protein.
Length = 684
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 413 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 472
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 473 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 525
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 526 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 585
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 586 SEFFEQGDRERLELKLTPSAIFDRN 610
>AJ251509-1|CAB82573.1| 490|Homo sapiens cyclic nucleotide
phosphodiesterase 11A1 protein.
Length = 490
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 219 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 278
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 279 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 331
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 332 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 391
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 392 SEFFEQGDRERLELKLTPSAIFDRN 416
>AF281865-1|AAG32023.1| 576|Homo sapiens cAMP/cGMP
phosphodiesterase 11A2 protein.
Length = 576
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 305 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 364
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 365 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 417
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 418 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 477
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 478 SEFFEQGDRERLELKLTPSAIFDRN 502
>AB048423-3|BAB62714.1| 490|Homo sapiens phosphodiesterase 11A1
protein.
Length = 490
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 219 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 278
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 279 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 331
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 332 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 391
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 392 SEFFEQGDRERLELKLTPSAIFDRN 416
>AB048423-2|BAB62712.1| 934|Homo sapiens phosphodiesterase 11A4
protein.
Length = 934
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 663 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 722
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 723 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 775
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 776 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 835
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 836 SEFFEQGDRERLELKLTPSAIFDRN 860
>AB048423-1|BAB62713.2| 684|Homo sapiens phosphodiesterase 11A3
protein.
Length = 684
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 413 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 472
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 473 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 525
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 526 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 585
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 586 SEFFEQGDRERLELKLTPSAIFDRN 610
>AB038041-1|BAB16372.1| 684|Homo sapiens phosphodiesterase 11A3
protein.
Length = 684
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 413 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 472
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 473 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 525
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 526 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 585
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 586 SEFFEQGDRERLELKLTPSAIFDRN 610
>AB036704-1|BAB16371.1| 934|Homo sapiens phosphodiesterase 11A
protein.
Length = 934
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 4/205 (1%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 663 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 722
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 723 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 775
Query: 417 DITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVC 596
D+T + + F +L+ D I+ HR + + + D+ +PW +S++ + V
Sbjct: 776 DLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVT 835
Query: 597 EEFFRQGDYEKM-LDLPVTQLCDRD 668
EFF QGD E++ L L + + DR+
Sbjct: 836 SEFFEQGDRERLELKLTPSAIFDRN 860
>U66349-1|AAB96878.1| 427|Homo sapiens PDE4C-delta109 protein.
Length = 427
Score = 96.3 bits (229), Expect = 1e-19
Identities = 58/191 (30%), Positives = 108/191 (56%), Gaps = 9/191 (4%)
Frame = +3
Query: 135 RAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHW 314
+A +EI+A L ++ HD+ HPGV+ FLI T + LA +Y + SVLE+HH
Sbjct: 125 QAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYN-------DASVLENHHL 177
Query: 315 RAALSCI-IESGLLEERPDLQEELKKHLKVL--IMATDITRQHDYLSRFKKLLDTN---T 476
+ E+ + + ++ L V+ ++ATD+++ + L+ K +++T +
Sbjct: 178 AVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 237
Query: 477 LDMRIQEH---RILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPV 647
L + + ++ RI VLQ + CAD+SNP +P + ++W+ ++ EFF+QGD E+ L +
Sbjct: 238 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 297
Query: 648 TQLCDRDSTSI 680
+ +CD+ + S+
Sbjct: 298 SPMCDKHTASV 308
>AY495087-1|AAS75513.1| 932|Homo sapiens cGMP-stimulated
phosphodiesterase 4 protein.
Length = 932
Score = 96.3 bits (229), Expect = 1e-19
Identities = 64/223 (28%), Positives = 110/223 (49%), Gaps = 6/223 (2%)
Frame = +3
Query: 33 LFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRA--FIRPVEIIACLLSAIAHDIFHP 206
+ + GY PYHN +HA + C+LL ++ ++ +EI A +S + HD+ H
Sbjct: 636 MVKKGYRDP-PYHNWMHAFSASH--FCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHR 692
Query: 207 GVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLE--ERPDLQ 374
G N F +A+ + LA LY S SV+E HH+ A++ + G + + R D Q
Sbjct: 693 GTNNSFQVASKSVLAALY------SSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQ 746
Query: 375 EELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPC 554
L ++ +I+ATD+ +K+ + Q HR+L+ + C D+S+
Sbjct: 747 RMLDL-MRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSC-DLSDQT 804
Query: 555 RPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSIP 683
+ W ++K + + +EFF QGD EK + ++ DR+ IP
Sbjct: 805 KGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIP 847
>AC005759-4|AAC83048.1| 427|Homo sapiens PDE4C-delta109 protein.
Length = 427
Score = 96.3 bits (229), Expect = 1e-19
Identities = 58/191 (30%), Positives = 108/191 (56%), Gaps = 9/191 (4%)
Frame = +3
Query: 135 RAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHW 314
+A +EI+A L ++ HD+ HPGV+ FLI T + LA +Y + SVLE+HH
Sbjct: 125 QAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYN-------DASVLENHHL 177
Query: 315 RAALSCI-IESGLLEERPDLQEELKKHLKVL--IMATDITRQHDYLSRFKKLLDTN---T 476
+ E+ + + ++ L V+ ++ATD+++ + L+ K +++T +
Sbjct: 178 AVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS 237
Query: 477 LDMRIQEH---RILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPV 647
L + + ++ RI VLQ + CAD+SNP +P + ++W+ ++ EFF+QGD E+ L +
Sbjct: 238 LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI 297
Query: 648 TQLCDRDSTSI 680
+ +CD+ + S+
Sbjct: 298 SPMCDKHTASV 308
>D89094-1|BAA28945.1| 875|Homo sapiens 3',5'-cyclic GMP
phosphodiesterase protein.
Length = 875
Score = 93.9 bits (223), Expect = 7e-19
Identities = 64/214 (29%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ Y YHN HA + Q M L G I+ + +EI+A L++A++HD+ H GVN
Sbjct: 603 KKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNN 662
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK 398
++ + + LA LY S++E HH+ L + G EE K LK
Sbjct: 663 SYIQRSEHPLAQLY--------CHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLK 714
Query: 399 VL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I+ATD+ F +L+ N ++ + L L + + D+S +PW +
Sbjct: 715 IIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPI 774
Query: 570 SQKWSVKVCEEFFRQGDYE-KMLDLPVTQLCDRD 668
Q+ + V EFF QGD E K L++ T L +R+
Sbjct: 775 QQRIAELVATEFFDQGDRERKELNIEPTDLMNRE 808
>BC126233-1|AAI26234.1| 875|Homo sapiens phosphodiesterase 5A,
cGMP-specific protein.
Length = 875
Score = 93.9 bits (223), Expect = 7e-19
Identities = 64/214 (29%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ Y YHN HA + Q M L G I+ + +EI+A L++A++HD+ H GVN
Sbjct: 603 KKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNN 662
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK 398
++ + + LA LY S++E HH+ L + G EE K LK
Sbjct: 663 SYIQRSEHPLAQLY--------CHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLK 714
Query: 399 VL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I+ATD+ F +L+ N ++ + L L + + D+S +PW +
Sbjct: 715 IIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPI 774
Query: 570 SQKWSVKVCEEFFRQGDYE-KMLDLPVTQLCDRD 668
Q+ + V EFF QGD E K L++ T L +R+
Sbjct: 775 QQRIAELVATEFFDQGDRERKELNIEPTDLMNRE 808
>AY264918-1|AAP21809.1| 833|Homo sapiens phosphodiesterase 5A
protein.
Length = 833
Score = 93.9 bits (223), Expect = 7e-19
Identities = 64/214 (29%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ Y YHN HA + Q M L G I+ + +EI+A L++A++HD+ H GVN
Sbjct: 561 KKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNN 620
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK 398
++ + + LA LY S++E HH+ L + G EE K LK
Sbjct: 621 SYIQRSEHPLAQLY--------CHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLK 672
Query: 399 VL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I+ATD+ F +L+ N ++ + L L + + D+S +PW +
Sbjct: 673 IIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPI 732
Query: 570 SQKWSVKVCEEFFRQGDYE-KMLDLPVTQLCDRD 668
Q+ + V EFF QGD E K L++ T L +R+
Sbjct: 733 QQRIAELVATEFFDQGDRERKELNIEPTDLMNRE 766
>AJ004865-1|CAA06170.1| 875|Homo sapiens cGMP-binding, cGMP-specific
phosphodiesterase (HSPDE5A1) protein.
Length = 875
Score = 93.9 bits (223), Expect = 7e-19
Identities = 64/214 (29%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ Y YHN HA + Q M L G I+ + +EI+A L++A++HD+ H GVN
Sbjct: 603 KKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNN 662
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK 398
++ + + LA LY S++E HH+ L + G EE K LK
Sbjct: 663 SYIQRSEHPLAQLY--------CHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLK 714
Query: 399 VL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I+ATD+ F +L+ N ++ + L L + + D+S +PW +
Sbjct: 715 IIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPI 774
Query: 570 SQKWSVKVCEEFFRQGDYE-KMLDLPVTQLCDRD 668
Q+ + V EFF QGD E K L++ T L +R+
Sbjct: 775 QQRIAELVATEFFDQGDRERKELNIEPTDLMNRE 808
>AF043731-1|AAC63967.1| 875|Homo sapiens cGMP-binding cGMP-specific
3',5'-cyclic nucleotide phosphodiesterase protein.
Length = 875
Score = 93.9 bits (223), Expect = 7e-19
Identities = 64/214 (29%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ Y YHN HA + Q M L G I+ + +EI+A L++A++HD+ H GVN
Sbjct: 603 KKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNN 662
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK 398
++ + + LA LY S++E HH+ L + G EE K LK
Sbjct: 663 SYIQRSEHPLAQLY--------CHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLK 714
Query: 399 VL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I+ATD+ F +L+ N ++ + L L + + D+S +PW +
Sbjct: 715 IIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPI 774
Query: 570 SQKWSVKVCEEFFRQGDYE-KMLDLPVTQLCDRD 668
Q+ + V EFF QGD E K L++ T L +R+
Sbjct: 775 QQRIAELVATEFFDQGDRERKELNIEPTDLMNRE 808
>AC093752-1|AAY40985.1| 331|Homo sapiens unknown protein.
Length = 331
Score = 93.9 bits (223), Expect = 7e-19
Identities = 64/214 (29%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ Y YHN HA + Q M L G I+ + +EI+A L++A++HD+ H GVN
Sbjct: 59 KKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNN 118
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK 398
++ + + LA LY S++E HH+ L + G EE K LK
Sbjct: 119 SYIQRSEHPLAQLY--------CHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLK 170
Query: 399 VL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I+ATD+ F +L+ N ++ + L L + + D+S +PW +
Sbjct: 171 IIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPI 230
Query: 570 SQKWSVKVCEEFFRQGDYE-KMLDLPVTQLCDRD 668
Q+ + V EFF QGD E K L++ T L +R+
Sbjct: 231 QQRIAELVATEFFDQGDRERKELNIEPTDLMNRE 264
>AB001635-1|BAA33372.2| 875|Homo sapiens cGMP-binding cGMP-specific
phosphodiesterase protein.
Length = 875
Score = 93.9 bits (223), Expect = 7e-19
Identities = 64/214 (29%), Positives = 103/214 (48%), Gaps = 4/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ Y YHN HA + Q M L G I+ + +EI+A L++A++HD+ H GVN
Sbjct: 603 KKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNN 662
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK 398
++ + + LA LY S++E HH+ L + G EE K LK
Sbjct: 663 SYIQRSEHPLAQLY--------CHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLK 714
Query: 399 VL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I+ATD+ F +L+ N ++ + L L + + D+S +PW +
Sbjct: 715 IIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPI 774
Query: 570 SQKWSVKVCEEFFRQGDYE-KMLDLPVTQLCDRD 668
Q+ + V EFF QGD E K L++ T L +R+
Sbjct: 775 QQRIAELVATEFFDQGDRERKELNIEPTDLMNRE 808
>U36798-1|AAB18673.1| 1141|Homo sapiens platelet cGI-PDE protein.
Length = 1141
Score = 92.7 bits (220), Expect = 2e-18
Identities = 59/190 (31%), Positives = 96/190 (50%), Gaps = 5/190 (2%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 815 GCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYN-------DRSVLEN 867
Query: 306 HHWRAALSCIIESGLLEERPDLQEELKKHLKVL----IMATDITRQHDYLSRFK-KLLDT 470
HH AA + + +L KH + L I+ATD+ + D++++F K+ D
Sbjct: 868 HHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDD 927
Query: 471 NTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
+D + R+LV Q+ +K ADI+ P + + +W+ + EF+ QGD E L LP++
Sbjct: 928 VGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPIS 987
Query: 651 QLCDRDSTSI 680
DR + +
Sbjct: 988 PFMDRSAPQL 997
Score = 31.9 bits (69), Expect = 3.0
Identities = 15/27 (55%), Positives = 16/27 (59%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E GY PYHN IHATDV A+
Sbjct: 739 FHALEIGYRDI-PYHNRIHATDVLHAV 764
>M91667-1|AAA35912.2| 1141|Homo sapiens cGMP-inhibited cAMP
phosphodiesterase protein.
Length = 1141
Score = 92.7 bits (220), Expect = 2e-18
Identities = 59/190 (31%), Positives = 96/190 (50%), Gaps = 5/190 (2%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 815 GCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYN-------DRSVLEN 867
Query: 306 HHWRAALSCIIESGLLEERPDLQEELKKHLKVL----IMATDITRQHDYLSRFK-KLLDT 470
HH AA + + +L KH + L I+ATD+ + D++++F K+ D
Sbjct: 868 HHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDD 927
Query: 471 NTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
+D + R+LV Q+ +K ADI+ P + + +W+ + EF+ QGD E L LP++
Sbjct: 928 VGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPIS 987
Query: 651 QLCDRDSTSI 680
DR + +
Sbjct: 988 PFMDRSAPQL 997
Score = 31.9 bits (69), Expect = 3.0
Identities = 15/27 (55%), Positives = 16/27 (59%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E GY PYHN IHATDV A+
Sbjct: 739 FHALEIGYRDI-PYHNRIHATDVLHAV 764
>BC117371-1|AAI17372.1| 1141|Homo sapiens phosphodiesterase 3A,
cGMP-inhibited protein.
Length = 1141
Score = 92.7 bits (220), Expect = 2e-18
Identities = 59/190 (31%), Positives = 96/190 (50%), Gaps = 5/190 (2%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 815 GCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYN-------DRSVLEN 867
Query: 306 HHWRAALSCIIESGLLEERPDLQEELKKHLKVL----IMATDITRQHDYLSRFK-KLLDT 470
HH AA + + +L KH + L I+ATD+ + D++++F K+ D
Sbjct: 868 HHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDD 927
Query: 471 NTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
+D + R+LV Q+ +K ADI+ P + + +W+ + EF+ QGD E L LP++
Sbjct: 928 VGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPIS 987
Query: 651 QLCDRDSTSI 680
DR + +
Sbjct: 988 PFMDRSAPQL 997
Score = 31.9 bits (69), Expect = 3.0
Identities = 15/27 (55%), Positives = 16/27 (59%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E GY PYHN IHATDV A+
Sbjct: 739 FHALEIGYRDI-PYHNRIHATDVLHAV 764
>BC117369-1|AAI17370.1| 1141|Homo sapiens phosphodiesterase 3A,
cGMP-inhibited protein.
Length = 1141
Score = 92.7 bits (220), Expect = 2e-18
Identities = 59/190 (31%), Positives = 96/190 (50%), Gaps = 5/190 (2%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 815 GCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYN-------DRSVLEN 867
Query: 306 HHWRAALSCIIESGLLEERPDLQEELKKHLKVL----IMATDITRQHDYLSRFK-KLLDT 470
HH AA + + +L KH + L I+ATD+ + D++++F K+ D
Sbjct: 868 HHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDD 927
Query: 471 NTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
+D + R+LV Q+ +K ADI+ P + + +W+ + EF+ QGD E L LP++
Sbjct: 928 VGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPIS 987
Query: 651 QLCDRDSTSI 680
DR + +
Sbjct: 988 PFMDRSAPQL 997
Score = 31.9 bits (69), Expect = 3.0
Identities = 15/27 (55%), Positives = 16/27 (59%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E GY PYHN IHATDV A+
Sbjct: 739 FHALEIGYRDI-PYHNRIHATDVLHAV 764
>AJ005036-1|CAA06304.1| 1141|Homo sapiens phosphodiesterase 3A
protein.
Length = 1141
Score = 92.7 bits (220), Expect = 2e-18
Identities = 59/190 (31%), Positives = 96/190 (50%), Gaps = 5/190 (2%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 815 GCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYN-------DRSVLEN 867
Query: 306 HHWRAALSCIIESGLLEERPDLQEELKKHLKVL----IMATDITRQHDYLSRFK-KLLDT 470
HH AA + + +L KH + L I+ATD+ + D++++F K+ D
Sbjct: 868 HHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNGKVNDD 927
Query: 471 NTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
+D + R+LV Q+ +K ADI+ P + + +W+ + EF+ QGD E L LP++
Sbjct: 928 VGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYEQGDEEASLGLPIS 987
Query: 651 QLCDRDSTSI 680
DR + +
Sbjct: 988 PFMDRSAPQL 997
Score = 31.9 bits (69), Expect = 3.0
Identities = 15/27 (55%), Positives = 16/27 (59%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E GY PYHN IHATDV A+
Sbjct: 739 FHALEIGYRDI-PYHNRIHATDVLHAV 764
>AB015656-1|BAA81667.1| 833|Homo sapiens cGMP-binding cGMP specific
phosphodiesterase 5A2 protein.
Length = 833
Score = 91.1 bits (216), Expect = 5e-18
Identities = 63/214 (29%), Positives = 102/214 (47%), Gaps = 4/214 (1%)
Frame = +3
Query: 39 ESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQ 218
+ Y YHN HA + Q M L G I+ + + I+A L++A++HD+ H GVN
Sbjct: 561 KKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLGILALLIAALSHDLDHRGVNN 620
Query: 219 GFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGLLEERPDLQEELKKHLK 398
++ + + LA LY S++E HH+ L + G EE K LK
Sbjct: 621 SYIQRSEHPLAQLY--------CHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLK 672
Query: 399 VL---IMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSV 569
++ I+ATD+ F +L+ N ++ + L L + + D+S +PW +
Sbjct: 673 IIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPI 732
Query: 570 SQKWSVKVCEEFFRQGDYE-KMLDLPVTQLCDRD 668
Q+ + V EFF QGD E K L++ T L +R+
Sbjct: 733 QQRIAELVATEFFDQGDRERKELNIEPTDLMNRE 766
>X95520-1|CAA64774.1| 1112|Homo sapiens cyclic nucleotide
phosphodiesterase protein.
Length = 1112
Score = 89.8 bits (213), Expect = 1e-17
Identities = 60/192 (31%), Positives = 99/192 (51%), Gaps = 7/192 (3%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 800 GCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYN-------DRSVLEN 852
Query: 306 HHWRAALSCII---ESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFK-KLLDT 470
HH +A + + E L ++ + + L + I+ATD+ + D+L+ F K D
Sbjct: 853 HHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDV 912
Query: 471 NT--LDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLP 644
N+ ++ + R+LV Q+ +K ADI+ P + + KW+ + EF+ QGD E L LP
Sbjct: 913 NSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLP 972
Query: 645 VTQLCDRDSTSI 680
++ DR S +
Sbjct: 973 ISPFMDRSSPQL 984
Score = 33.5 bits (73), Expect = 1.00
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E+GY PYHN IHATDV A+
Sbjct: 724 FRALENGYRDI-PYHNRIHATDVLHAV 749
>U38178-1|AAC50724.1| 1112|Homo sapiens cyclic nucleotide
phophodiesterase protein.
Length = 1112
Score = 89.8 bits (213), Expect = 1e-17
Identities = 60/192 (31%), Positives = 99/192 (51%), Gaps = 7/192 (3%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 800 GCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYN-------DRSVLEN 852
Query: 306 HHWRAALSCII---ESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFK-KLLDT 470
HH +A + + E L ++ + + L + I+ATD+ + D+L+ F K D
Sbjct: 853 HHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDV 912
Query: 471 NT--LDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLP 644
N+ ++ + R+LV Q+ +K ADI+ P + + KW+ + EF+ QGD E L LP
Sbjct: 913 NSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLP 972
Query: 645 VTQLCDRDSTSI 680
++ DR S +
Sbjct: 973 ISPFMDRSSPQL 984
Score = 33.5 bits (73), Expect = 1.00
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E+GY PYHN IHATDV A+
Sbjct: 724 FRALENGYRDI-PYHNRIHATDVLHAV 749
>D50640-1|BAA09306.1| 1112|Homo sapiens phosphodiesterase 3B protein.
Length = 1112
Score = 89.8 bits (213), Expect = 1e-17
Identities = 60/192 (31%), Positives = 99/192 (51%), Gaps = 7/192 (3%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 800 GCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYN-------DRSVLEN 852
Query: 306 HHWRAALSCII---ESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFK-KLLDT 470
HH +A + + E L ++ + + L + I+ATD+ + D+L+ F K D
Sbjct: 853 HHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDV 912
Query: 471 NT--LDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLP 644
N+ ++ + R+LV Q+ +K ADI+ P + + KW+ + EF+ QGD E L LP
Sbjct: 913 NSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLP 972
Query: 645 VTQLCDRDSTSI 680
++ DR S +
Sbjct: 973 ISPFMDRSSPQL 984
Score = 33.5 bits (73), Expect = 1.00
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E+GY PYHN IHATDV A+
Sbjct: 724 FRALENGYRDI-PYHNRIHATDVLHAV 749
>BC150307-1|AAI50308.1| 1112|Homo sapiens phosphodiesterase 3B,
cGMP-inhibited protein.
Length = 1112
Score = 89.8 bits (213), Expect = 1e-17
Identities = 60/192 (31%), Positives = 99/192 (51%), Gaps = 7/192 (3%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 800 GCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYN-------DRSVLEN 852
Query: 306 HHWRAALSCII---ESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFK-KLLDT 470
HH +A + + E L ++ + + L + I+ATD+ + D+L+ F K D
Sbjct: 853 HHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDV 912
Query: 471 NT--LDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLP 644
N+ ++ + R+LV Q+ +K ADI+ P + + KW+ + EF+ QGD E L LP
Sbjct: 913 NSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLP 972
Query: 645 VTQLCDRDSTSI 680
++ DR S +
Sbjct: 973 ISPFMDRSSPQL 984
Score = 33.5 bits (73), Expect = 1.00
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E+GY PYHN IHATDV A+
Sbjct: 724 FRALENGYRDI-PYHNRIHATDVLHAV 749
>AY459346-1|AAR24292.1| 1112|Homo sapiens cGMP-inhibited cAMP
phophodiesterase protein.
Length = 1112
Score = 89.8 bits (213), Expect = 1e-17
Identities = 60/192 (31%), Positives = 99/192 (51%), Gaps = 7/192 (3%)
Frame = +3
Query: 126 GSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLES 305
G + + I +E++A ++A HD HPG FL+AT A LY + SVLE+
Sbjct: 800 GCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYN-------DRSVLEN 852
Query: 306 HHWRAALSCII---ESGLLEERPDLQEELKKHLKV-LIMATDITRQHDYLSRFK-KLLDT 470
HH +A + + E L ++ + + L + I+ATD+ + D+L+ F K D
Sbjct: 853 HHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDV 912
Query: 471 NT--LDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLP 644
N+ ++ + R+LV Q+ +K ADI+ P + + KW+ + EF+ QGD E L LP
Sbjct: 913 NSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLP 972
Query: 645 VTQLCDRDSTSI 680
++ DR S +
Sbjct: 973 ISPFMDRSSPQL 984
Score = 33.5 bits (73), Expect = 1.00
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +3
Query: 27 FTLFESGYHSTNPYHNSIHATDVTQAM 107
F E+GY PYHN IHATDV A+
Sbjct: 724 FRALENGYRDI-PYHNRIHATDVLHAV 749
>BC047627-1|AAH47627.1| 241|Homo sapiens PDE8B protein protein.
Length = 241
Score = 89.4 bits (212), Expect = 1e-17
Identities = 55/192 (28%), Positives = 99/192 (51%), Gaps = 18/192 (9%)
Frame = +3
Query: 162 IACLLSAIAHDIFHPGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIE 341
+A L++A HD+ HPG FL + LA LY + +VLESHH A ++
Sbjct: 2 VAALIAATVHDVDHPGRTNSFLCNAGSELAVLYN-------DTAVLESHHTALAFQLTVK 54
Query: 342 SGLLEERPDLQEE----LKKHLKVLIMATDITRQHDYLSRFKKLL-------------DT 470
++ L++ + +++AT++T+ +++++F + +
Sbjct: 55 DTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCEC 114
Query: 471 NTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
N E++IL+ ++ +KCAD++NPCRP + +W+ ++ EE+F Q D EK LPV
Sbjct: 115 NPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVV 174
Query: 651 Q-LCDRDSTSIP 683
+ DR++ SIP
Sbjct: 175 MPVFDRNTCSIP 186
>U40584-1|AAB50018.1| 184|Homo sapiens
calcium/calmodulin-stimulated cyclic nucleotide
phosphodiesterase protein.
Length = 184
Score = 89.0 bits (211), Expect = 2e-17
Identities = 59/185 (31%), Positives = 93/185 (50%), Gaps = 4/185 (2%)
Frame = +3
Query: 39 ESGYHS-TNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVN 215
E+GY NPYHN IHA DVTQ +HCFLL+ + + +E++A + +A HD H G
Sbjct: 12 ETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTT 71
Query: 216 QGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL---LEERPDLQEELK 386
F I T + A +Y + SVLE+HH + + + + + D EL+
Sbjct: 72 NSFHIQTKSECAIVY-------NDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELR 124
Query: 387 KHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWS 566
+ +++ATD++ + K L L+ RI + + L + L ADIS+P + W
Sbjct: 125 ALVIEMVLATDMSCHFQQVKTMKTAL--QQLE-RIDKSK--ALSLLLHAADISHPTKQWL 179
Query: 567 VSQKW 581
V +W
Sbjct: 180 VHSRW 184
>X90587-1|CAA62215.1| 617|Homo sapiens Rod cGMP phosphodiesterase
protein.
Length = 617
Score = 75.8 bits (178), Expect = 2e-13
Identities = 62/232 (26%), Positives = 105/232 (45%), Gaps = 14/232 (6%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
LF++ GY YHN H +V Q M L+ G ++++ +E A + + + HDI H
Sbjct: 307 LFSI-SKGYRRIT-YHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDH 364
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQE 377
G N + + + N LA L+ S+LE HH + E + + Q
Sbjct: 365 RGTNNLYQMKSQNPLAKLH--------GSSILERHHLEFGKFLLSEETLNIYQNLNRRQH 416
Query: 378 ELKKHL-KVLIMATDITRQHDYLSRFKKLLD--TNTLDMRI--------QEHRILVLQIA 524
E HL + I+ATD+ + F+K++D N D + + +V+ +
Sbjct: 417 EHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLSLETTRKEIVMAMM 476
Query: 525 LKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTS 677
+ D+S +PW V K ++ V EF+ QGD E+ +LD + DR+ +
Sbjct: 477 MTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAA 528
>X66142-1|CAA46932.1| 854|Homo sapiens 3',5'-cyclic-nucleotide
phosphodiesterase protein.
Length = 854
Score = 75.8 bits (178), Expect = 2e-13
Identities = 62/232 (26%), Positives = 105/232 (45%), Gaps = 14/232 (6%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
LF++ GY YHN H +V Q M L+ G ++++ +E A + + + HDI H
Sbjct: 544 LFSI-SKGYRRIT-YHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDH 601
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQE 377
G N + + + N LA L+ S+LE HH + E + + Q
Sbjct: 602 RGTNNLYQMKSQNPLAKLH--------GSSILERHHLEFGKFLLSEETLNIYQNLNRRQH 653
Query: 378 ELKKHL-KVLIMATDITRQHDYLSRFKKLLD--TNTLDMRI--------QEHRILVLQIA 524
E HL + I+ATD+ + F+K++D N D + + +V+ +
Sbjct: 654 EHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLSLETTRKEIVMAMM 713
Query: 525 LKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTS 677
+ D+S +PW V K ++ V EF+ QGD E+ +LD + DR+ +
Sbjct: 714 MTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAA 765
>X62692-1|CAA44569.1| 854|Homo sapiens cGMP phosphodiesterase beta
subunit protein.
Length = 854
Score = 75.8 bits (178), Expect = 2e-13
Identities = 62/232 (26%), Positives = 105/232 (45%), Gaps = 14/232 (6%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
LF++ GY YHN H +V Q M L+ G ++++ +E A + + + HDI H
Sbjct: 544 LFSI-SKGYRRIT-YHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDH 601
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQE 377
G N + + + N LA L+ S+LE HH + E + + Q
Sbjct: 602 RGTNNLYQMKSQNPLAKLH--------GSSILERHHLEFGKFLLSEETLNIYQNLNRRQH 653
Query: 378 ELKKHL-KVLIMATDITRQHDYLSRFKKLLD--TNTLDMRI--------QEHRILVLQIA 524
E HL + I+ATD+ + F+K++D N D + + +V+ +
Sbjct: 654 EHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEILSLETTRKEIVMAMM 713
Query: 525 LKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTS 677
+ D+S +PW V K ++ V EF+ QGD E+ +LD + DR+ +
Sbjct: 714 MTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAA 765
>S41458-1|AAB22690.1| 854|Homo sapiens rod cGMP phosphodiesterase
beta-subunit protein.
Length = 854
Score = 75.8 bits (178), Expect = 2e-13
Identities = 62/232 (26%), Positives = 105/232 (45%), Gaps = 14/232 (6%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
LF++ GY YHN H +V Q M L+ G ++++ +E A + + + HDI H
Sbjct: 544 LFSI-SKGYRRIT-YHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDH 601
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQE 377
G N + + + N LA L+ S+LE HH + E + + Q
Sbjct: 602 RGTNNLYQMKSQNPLAKLH--------GSSILERHHLEFGKFLLSEETLNIYQNLNRRQH 653
Query: 378 ELKKHL-KVLIMATDITRQHDYLSRFKKLLD--TNTLDMRI--------QEHRILVLQIA 524
E HL + I+ATD+ + F+K++D N D + + +V+ +
Sbjct: 654 EHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLSLETTRKEIVMAMM 713
Query: 525 LKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTS 677
+ D+S +PW V K ++ V EF+ QGD E+ +LD + DR+ +
Sbjct: 714 MTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAA 765
>X94354-1|CAA64079.1| 858|Homo sapiens cone cGMP phosphodiesterase
protein.
Length = 858
Score = 74.9 bits (176), Expect = 3e-13
Identities = 69/273 (25%), Positives = 118/273 (43%), Gaps = 15/273 (5%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY + YHN H +V Q M L+ G ++ + +E A L +A HDI H G N +
Sbjct: 555 GYRAVT-YHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLY 613
Query: 225 LIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL--LEERPDLQEELKKHL- 395
+ + + LA L+ S+LE HH + + + + L + Q E HL
Sbjct: 614 QMKSTSPLARLH--------GSSILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLF 665
Query: 396 KVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRI-----------LVLQIALKCADI 542
+V I+ATD+ + F+K++D M+ +E I +++ + + D+
Sbjct: 666 EVAIIATDLALYFKKRTMFQKIVDA-CEQMQTEEEAIKYVTVDPTKKEIIMAMMMTACDL 724
Query: 543 SNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTSIPXNTNXLL*IYXS 719
S +PW V + ++ V EF+ QGD E+ +L + DR+ +
Sbjct: 725 SAITKPWEVQSQVALMVANEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVC 784
Query: 720 LPXITEWNRFLDSKLSXEMXANXXYNEVQWELL 818
E++RF K M + N V+W+ L
Sbjct: 785 TFVYKEFSRF--HKEITPMLSGLQNNRVEWKSL 815
>U31973-1|AAA96392.1| 858|Homo sapiens phosphodiesterase A' subunit
protein.
Length = 858
Score = 74.9 bits (176), Expect = 3e-13
Identities = 69/273 (25%), Positives = 118/273 (43%), Gaps = 15/273 (5%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY + YHN H +V Q M L+ G ++ + +E A L +A HDI H G N +
Sbjct: 555 GYRAVT-YHNWQHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLY 613
Query: 225 LIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL--LEERPDLQEELKKHL- 395
+ + + LA L+ S+LE HH + + + + L + Q E HL
Sbjct: 614 QMKSTSPLARLH--------GSSILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLF 665
Query: 396 KVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRI-----------LVLQIALKCADI 542
+V I+ATD+ + F+K++D M+ +E I +++ + + D+
Sbjct: 666 EVAIIATDLALYFKKRTMFQKIVDA-CEQMQTEEEAIKYVTVDPTKKEIIMAMMMTACDL 724
Query: 543 SNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTSIPXNTNXLL*IYXS 719
S +PW V + ++ V EF+ QGD E+ +L + DR+ +
Sbjct: 725 SAITKPWEVQSQVALMVANEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVC 784
Query: 720 LPXITEWNRFLDSKLSXEMXANXXYNEVQWELL 818
E++RF K M + N V+W+ L
Sbjct: 785 TFVYKEFSRF--HKEITPMLSGLQNNRVEWKSL 815
>U20212-1|AAA92886.1| 858|Homo sapiens cone photoreceptor
cGMP-phosphodiesterase alpha' subunit protein.
Length = 858
Score = 74.9 bits (176), Expect = 3e-13
Identities = 69/273 (25%), Positives = 118/273 (43%), Gaps = 15/273 (5%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY + YHN H +V Q M L+ G ++ + +E A L +A HDI H G N +
Sbjct: 555 GYRAVT-YHNWQHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLY 613
Query: 225 LIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL--LEERPDLQEELKKHL- 395
+ + + LA L+ S+LE HH + + + + L + Q E HL
Sbjct: 614 QMKSTSPLARLH--------GSSILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLF 665
Query: 396 KVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRI-----------LVLQIALKCADI 542
+V I+ATD+ + F+K++D M+ +E I +++ + + D+
Sbjct: 666 EVAIIATDLALYFKKRTMFQKIVDA-CEQMQTEEEAIKYVTVDPTKKEIIMAMMMTACDL 724
Query: 543 SNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTSIPXNTNXLL*IYXS 719
S +PW V + ++ V EF+ QGD E+ +L + DR+ +
Sbjct: 725 SAITKPWEVQSQVALMVANEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVC 784
Query: 720 LPXITEWNRFLDSKLSXEMXANXXYNEVQWELL 818
E++RF K M + N V+W+ L
Sbjct: 785 TFVYKEFSRF--HKEITPMLSGLQNNRVEWKSL 815
>AL356214-7|CAH72330.1| 858|Homo sapiens phosphodiesterase 6C,
cGMP-specific, cone, alpha prime protein.
Length = 858
Score = 74.9 bits (176), Expect = 3e-13
Identities = 69/273 (25%), Positives = 118/273 (43%), Gaps = 15/273 (5%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY + YHN H +V Q M L+ G ++ + +E A L +A HDI H G N +
Sbjct: 555 GYRAVT-YHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLY 613
Query: 225 LIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL--LEERPDLQEELKKHL- 395
+ + + LA L+ S+LE HH + + + + L + Q E HL
Sbjct: 614 QMKSTSPLARLH--------GSSILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLF 665
Query: 396 KVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRI-----------LVLQIALKCADI 542
+V I+ATD+ + F+K++D M+ +E I +++ + + D+
Sbjct: 666 EVAIIATDLALYFKKRTMFQKIVDA-CEQMQTEEEAIKYVTVDPTKKEIIMAMMMTACDL 724
Query: 543 SNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTSIPXNTNXLL*IYXS 719
S +PW V + ++ V EF+ QGD E+ +L + DR+ +
Sbjct: 725 SAITKPWEVQSQVALMVANEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVC 784
Query: 720 LPXITEWNRFLDSKLSXEMXANXXYNEVQWELL 818
E++RF K M + N V+W+ L
Sbjct: 785 TFVYKEFSRF--HKEITPMLSGLQNNRVEWKSL 815
>AL157396-4|CAH73839.1| 858|Homo sapiens phosphodiesterase 6C,
cGMP-specific, cone, alpha prime protein.
Length = 858
Score = 74.9 bits (176), Expect = 3e-13
Identities = 69/273 (25%), Positives = 118/273 (43%), Gaps = 15/273 (5%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY + YHN H +V Q M L+ G ++ + +E A L +A HDI H G N +
Sbjct: 555 GYRAVT-YHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLY 613
Query: 225 LIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL--LEERPDLQEELKKHL- 395
+ + + LA L+ S+LE HH + + + + L + Q E HL
Sbjct: 614 QMKSTSPLARLH--------GSSILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLF 665
Query: 396 KVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQEHRI-----------LVLQIALKCADI 542
+V I+ATD+ + F+K++D M+ +E I +++ + + D+
Sbjct: 666 EVAIIATDLALYFKKRTMFQKIVDA-CEQMQTEEEAIKYVTVDPTKKEIIMAMMMTACDL 724
Query: 543 SNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTSIPXNTNXLL*IYXS 719
S +PW V + ++ V EF+ QGD E+ +L + DR+ +
Sbjct: 725 SAITKPWEVQSQVALMVANEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVC 784
Query: 720 LPXITEWNRFLDSKLSXEMXANXXYNEVQWELL 818
E++RF K M + N V+W+ L
Sbjct: 785 TFVYKEFSRF--HKEITPMLSGLQNNRVEWKSL 815
>BT009794-1|AAP88796.1| 853|Homo sapiens phosphodiesterase 6B,
cGMP-specific, rod, beta (congenital stationary night bli
protein.
Length = 853
Score = 74.5 bits (175), Expect = 4e-13
Identities = 61/232 (26%), Positives = 105/232 (45%), Gaps = 14/232 (6%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
LF++ GY YHN H +V Q M L+ G ++++ +E A + + + HDI H
Sbjct: 544 LFSI-SKGYRRIT-YHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDH 601
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQE 377
G N + + + N LA L+ S+LE HH + E + + Q
Sbjct: 602 RGTNNLYQMKSQNPLAKLH--------GSSILERHHLEFGKFLLSEETLNIYQNLNRRQH 653
Query: 378 ELKKHL-KVLIMATDITRQHDYLSRFKKLLD--TNTLDMRI--------QEHRILVLQIA 524
+ HL + I+ATD+ + F+K++D N D + + +V+ +
Sbjct: 654 DHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLSLETTRKEIVMAMM 713
Query: 525 LKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTS 677
+ D+S +PW V K ++ V EF+ QGD E+ +LD + DR+ +
Sbjct: 714 MTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAA 765
>BC000249-1|AAH00249.1| 853|Homo sapiens phosphodiesterase 6B,
cGMP-specific, rod, beta (congenital stationary night bli
protein.
Length = 853
Score = 74.5 bits (175), Expect = 4e-13
Identities = 61/232 (26%), Positives = 105/232 (45%), Gaps = 14/232 (6%)
Frame = +3
Query: 24 LFTLFESGYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFH 203
LF++ GY YHN H +V Q M L+ G ++++ +E A + + + HDI H
Sbjct: 544 LFSI-SKGYRRIT-YHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDH 601
Query: 204 PGVNQGFLIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIES--GLLEERPDLQE 377
G N + + + N LA L+ S+LE HH + E + + Q
Sbjct: 602 RGTNNLYQMKSQNPLAKLH--------GSSILERHHLEFGKFLLSEETLNIYQNLNRRQH 653
Query: 378 ELKKHL-KVLIMATDITRQHDYLSRFKKLLD--TNTLDMRI--------QEHRILVLQIA 524
+ HL + I+ATD+ + F+K++D N D + + +V+ +
Sbjct: 654 DHVIHLMDIAIIATDLALYFKKRAMFQKIVDESKNYQDKKSWVEYLSLETTRKEIVMAMM 713
Query: 525 LKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEK-MLDLPVTQLCDRDSTS 677
+ D+S +PW V K ++ V EF+ QGD E+ +LD + DR+ +
Sbjct: 714 MTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAA 765
>M26061-1|AAB69155.1| 860|Homo sapiens PDEA protein.
Length = 860
Score = 74.1 bits (174), Expect = 6e-13
Identities = 56/208 (26%), Positives = 96/208 (46%), Gaps = 13/208 (6%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY YHN H +V Q M L+ G ++ + +E +A + +A HDI H G N +
Sbjct: 552 GYRKIT-YHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLY 610
Query: 225 LIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL--LEERPDLQEELKKH-L 395
+ + N LA L+ S+LE HH + + + L + Q E H +
Sbjct: 611 QMKSQNPLAKLH--------GSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMM 662
Query: 396 KVLIMATDITRQHDYLSRFKKLLD-TNTLD---------MRIQEHRILVLQIALKCADIS 545
+ I+ATD+ + F+K++D + T + M Q + +V+ + + D+S
Sbjct: 663 DIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWTQYMMLEQTRKEIVMAMMMTACDLS 722
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEK 629
+PW V + ++ V EF+ QGD E+
Sbjct: 723 AITKPWEVQSQVALLVAAEFWEQGDLER 750
>BC035909-1|AAH35909.1| 860|Homo sapiens phosphodiesterase 6A,
cGMP-specific, rod, alpha protein.
Length = 860
Score = 74.1 bits (174), Expect = 6e-13
Identities = 56/208 (26%), Positives = 96/208 (46%), Gaps = 13/208 (6%)
Frame = +3
Query: 45 GYHSTNPYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGF 224
GY YHN H +V Q M L+ G ++ + +E +A + +A HDI H G N +
Sbjct: 552 GYRKIT-YHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLY 610
Query: 225 LIATCNHLADLYRILEGTSENFSVLESHHWRAALSCIIESGL--LEERPDLQEELKKH-L 395
+ + N LA L+ S+LE HH + + + L + Q E H +
Sbjct: 611 QMKSQNPLAKLH--------GSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMM 662
Query: 396 KVLIMATDITRQHDYLSRFKKLLD-TNTLD---------MRIQEHRILVLQIALKCADIS 545
+ I+ATD+ + F+K++D + T + M Q + +V+ + + D+S
Sbjct: 663 DIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWTQYMMLEQTRKEIVMAMMMTACDLS 722
Query: 546 NPCRPWSVSQKWSVKVCEEFFRQGDYEK 629
+PW V + ++ V EF+ QGD E+
Sbjct: 723 AITKPWEVQSQVALLVAAEFWEQGDLER 750
>CR536567-1|CAG38804.1| 779|Homo sapiens PDE10A protein.
Length = 779
Score = 72.1 bits (169), Expect = 2e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 513 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 570
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 571 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 622
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 623 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVISLMMTACDLCSVTKLWPVTKLTANDI 682
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 683 YAEFWAEGDEMKKLGIQPIPMMDRD 707
>AL109778-1|CAB52432.1| 178|Homo sapiens PDE8A; phosphodiesterase
8A protein.
Length = 178
Score = 71.7 bits (168), Expect = 3e-12
Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 1/96 (1%)
Frame = +3
Query: 471 NTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
NT+ +R E+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV
Sbjct: 54 NTM-LRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVV 112
Query: 651 Q-LCDRDSTSIPXNTNXLL*IYXSLPXITEWNRFLD 755
+ DR++ SIP + + Y W+ F+D
Sbjct: 113 MPVFDRNTCSIPKSQISFI-DYFITDMFDAWDAFVD 147
>AL109687-1|CAB52020.1| 160|Homo sapiens PDE8A; phosphodiesterase
8A protein.
Length = 160
Score = 71.7 bits (168), Expect = 3e-12
Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 1/96 (1%)
Frame = +3
Query: 471 NTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVT 650
NT+ +R E+R L+ ++ +KCAD+SNPCRP +W+ ++ EE+F Q D EK LPV
Sbjct: 36 NTM-LRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVV 94
Query: 651 Q-LCDRDSTSIPXNTNXLL*IYXSLPXITEWNRFLD 755
+ DR++ SIP + + Y W+ F+D
Sbjct: 95 MPVFDRNTCSIPKSQISFI-DYFITDMFDAWDAFVD 129
>BC104860-1|AAI04861.1| 779|Homo sapiens phosphodiesterase 10A
protein.
Length = 779
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 513 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 570
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 571 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 622
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 623 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 682
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 683 YAEFWAEGDEMKKLGIQPIPMMDRD 707
>BC104858-1|AAI04859.1| 779|Homo sapiens phosphodiesterase 10A
protein.
Length = 779
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 513 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 570
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 571 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 622
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 623 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 682
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 683 YAEFWAEGDEMKKLGIQPIPMMDRD 707
>AL160160-1|CAH72023.1| 779|Homo sapiens phosphodiesterase 10A
protein.
Length = 779
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 513 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 570
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 571 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 622
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 623 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 682
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 683 YAEFWAEGDEMKKLGIQPIPMMDRD 707
>AL136130-1|CAI20436.1| 779|Homo sapiens phosphodiesterase 10A
protein.
Length = 779
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 513 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 570
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 571 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 622
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 623 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 682
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 683 YAEFWAEGDEMKKLGIQPIPMMDRD 707
>AL117345-1|CAB92797.2| 779|Homo sapiens phosphodiesterase 10A
protein.
Length = 779
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 513 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 570
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 571 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 622
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 623 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 682
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 683 YAEFWAEGDEMKKLGIQPIPMMDRD 707
>AF127480-1|AAD32596.1| 807|Homo sapiens 3',5'-cyclic nucleotide
phosphodiesterase 10A2 protein.
Length = 807
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 541 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 598
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 599 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 650
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 651 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 710
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 711 YAEFWAEGDEMKKLGIQPIPMMDRD 735
>AF127479-1|AAD32595.1| 779|Homo sapiens 3',5'-cyclic nucleotide
phosphodiesterase 10A1 protein.
Length = 779
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 513 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 570
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 571 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 622
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 623 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 682
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 683 YAEFWAEGDEMKKLGIQPIPMMDRD 707
>AB041798-3|BAB16383.1| 714|Homo sapiens phosphodiesterase 10A1
(PDE10A1) protein.
Length = 714
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 448 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 505
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 506 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 557
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 558 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 617
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 618 YAEFWAEGDEMKKLGIQPIPMMDRD 642
>AB026816-1|BAA84467.1| 789|Homo sapiens 3',5'-cyclic nucleotide
phosphodiesterase 10A2 protein.
Length = 789
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 523 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 580
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 581 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 632
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 633 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 692
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 693 YAEFWAEGDEMKKLGIQPIPMMDRD 717
>AB020593-1|BAA78034.1| 779|Homo sapiens 3',5'-Cyclic nucleotide
phosphodiesterase protein.
Length = 779
Score = 71.3 bits (167), Expect = 4e-12
Identities = 51/205 (24%), Positives = 97/205 (47%), Gaps = 3/205 (1%)
Frame = +3
Query: 63 PYHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCN 242
PYHN HA V M+ +LQ + F +E L++ + HD+ H G + +L +
Sbjct: 513 PYHNWKHAVTVAHCMYA-ILQNNHTLFT-DLERKGLLIACLCHDLDHRGFSNSYLQKFDH 570
Query: 243 HLADLYRILEGTSENFSVLESHHWRAALSCIIESG--LLEERPDLQ-EELKKHLKVLIMA 413
LA LY + S +E HH+ +S + G + + E++ + ++ I+A
Sbjct: 571 PLAALY--------STSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIA 622
Query: 414 TDITRQHDYLSRFKKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKV 593
TD+ + +++ T +L++ Q HR V+ + + D+ + + W V++ + +
Sbjct: 623 TDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDI 682
Query: 594 CEEFFRQGDYEKMLDLPVTQLCDRD 668
EF+ +GD K L + + DRD
Sbjct: 683 YAEFWAEGDEMKKLGIQPIPMMDRD 707
>L20968-1|AAA03591.1| 251|Homo sapiens phosphodiesterase protein.
Length = 251
Score = 67.3 bits (157), Expect = 7e-11
Identities = 32/106 (30%), Positives = 68/106 (64%), Gaps = 6/106 (5%)
Frame = +3
Query: 381 LKKHLKVLIMATDITRQHDYLSRFKKLLDTN---TLDMRIQEH---RILVLQIALKCADI 542
L++ + +++ATD+++ + L+ K +++T +L + + ++ RI VLQ + CAD+
Sbjct: 27 LRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADL 86
Query: 543 SNPCRPWSVSQKWSVKVCEEFFRQGDYEKMLDLPVTQLCDRDSTSI 680
SNP +P + ++W+ ++ EFF+QGD E+ L ++ +CD+ + S+
Sbjct: 87 SNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV 132
>M94539-1|AAA58405.1| 116|Homo sapiens cyclic nucleotide
phosphodiesterase protein.
Length = 116
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/122 (31%), Positives = 64/122 (52%), Gaps = 3/122 (2%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHNS+HA DVTQ +HCFLL+ + + +E++A + +A HD H G F I T +
Sbjct: 1 YHNSMHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSE 60
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESGL---LEERPDLQEELKKHLKVLIMAT 416
A +Y + SVLE+HH + + + + + D EL+ + +++AT
Sbjct: 61 CAIVY-------NDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLAT 113
Query: 417 DI 422
D+
Sbjct: 114 DM 115
>U86077-1|AAC51871.1| 71|Homo sapiens calmodulin-stimulated
phosphodiesterase PDE1B1 protein.
Length = 71
Score = 60.5 bits (140), Expect = 8e-09
Identities = 27/65 (41%), Positives = 38/65 (58%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN IHA DVTQ +HCFLL+ + + +E++A + +A HD H G F I T +
Sbjct: 1 YHNLIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSE 60
Query: 246 LADLY 260
A +Y
Sbjct: 61 CAIVY 65
>AY266362-1|AAP31234.1| 102|Homo sapiens phosphodiesterase isozyme
4 protein.
Length = 102
Score = 60.5 bits (140), Expect = 8e-09
Identities = 25/76 (32%), Positives = 47/76 (61%)
Frame = +3
Query: 453 KKLLDTNTLDMRIQEHRILVLQIALKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKM 632
KK+ + L + RI VL+ + CAD+SNP +P + ++W+ ++ EFF+QGD E+
Sbjct: 5 KKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERE 64
Query: 633 LDLPVTQLCDRDSTSI 680
+ ++ +CD+ + S+
Sbjct: 65 RGMEISPMCDKHTASV 80
>AC012499-1|AAY14803.1| 325|Homo sapiens unknown protein.
Length = 325
Score = 58.4 bits (135), Expect = 3e-08
Identities = 40/123 (32%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +3
Query: 66 YHNSIHATDVTQAMHCFLLQGSIRAFIRPVEIIACLLSAIAHDIFHPGVNQGFLIATCNH 245
YHN HA +V Q M L + + VEI+A ++ + HD+ H G N F + +
Sbjct: 207 YHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSA 266
Query: 246 LADLYRILEGTSENFSVLESHHWRAALSCIIESG---LLEERPDLQEELKKHLKVLIMAT 416
LA LY GTS + LE HH+ A+ + G +L + LK I+AT
Sbjct: 267 LAQLY----GTS---ATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILAT 319
Query: 417 DIT 425
D+T
Sbjct: 320 DLT 322
>BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 35.1 bits (77), Expect = 0.33
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 315 RAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQ 494
R ALS +++ LL+E+ +EEL++ L L ++ +++ +L ++++LL+ L +++Q
Sbjct: 508 RWALSSLLQQ-LLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQ 566
Query: 495 E 497
E
Sbjct: 567 E 567
>AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein
protein.
Length = 723
Score = 35.1 bits (77), Expect = 0.33
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 315 RAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQ 494
R ALS +++ LL+E+ +EEL++ L L ++ +++ +L ++++LL+ L +++Q
Sbjct: 508 RWALSSLLQQ-LLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQ 566
Query: 495 E 497
E
Sbjct: 567 E 567
>AL445222-17|CAH72931.1| 696|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 696
Score = 35.1 bits (77), Expect = 0.33
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 315 RAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQ 494
R ALS +++ LL+E+ +EEL++ L L ++ +++ +L ++++LL+ L +++Q
Sbjct: 481 RWALSSLLQQ-LLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQ 539
Query: 495 E 497
E
Sbjct: 540 E 540
>AL445222-16|CAH72930.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 35.1 bits (77), Expect = 0.33
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 315 RAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQ 494
R ALS +++ LL+E+ +EEL++ L L ++ +++ +L ++++LL+ L +++Q
Sbjct: 508 RWALSSLLQQ-LLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQ 566
Query: 495 E 497
E
Sbjct: 567 E 567
>AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens
cDNA FLJ34270 fis, clone FEBRA2003100. ).
Length = 723
Score = 35.1 bits (77), Expect = 0.33
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 315 RAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQ 494
R ALS +++ LL+E+ +EEL++ L L ++ +++ +L ++++LL+ L +++Q
Sbjct: 508 RWALSSLLQQ-LLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQ 566
Query: 495 E 497
E
Sbjct: 567 E 567
>AK056305-1|BAB71144.1| 303|Homo sapiens protein ( Homo sapiens
cDNA FLJ31743 fis, clone NT2RI2007254, weakly similar to
Arabidopsis thaliana ZCF61 mRNA. ).
Length = 303
Score = 35.1 bits (77), Expect = 0.33
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 315 RAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQ 494
R ALS +++ LL+E+ +EEL++ L L ++ +++ +L ++++LL+ L +++Q
Sbjct: 88 RWALSSLLQQ-LLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQ 146
Query: 495 E 497
E
Sbjct: 147 E 147
>AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens
cDNA FLJ31641 fis, clone NT2RI2003695, weakly similar to
TRICHOHYALIN. ).
Length = 696
Score = 35.1 bits (77), Expect = 0.33
Identities = 18/61 (29%), Positives = 40/61 (65%)
Frame = +3
Query: 315 RAALSCIIESGLLEERPDLQEELKKHLKVLIMATDITRQHDYLSRFKKLLDTNTLDMRIQ 494
R ALS +++ LL+E+ +EEL++ L L ++ +++ +L ++++LL+ L +++Q
Sbjct: 481 RWALSSLLQQ-LLKEKQQREEELREILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQ 539
Query: 495 E 497
E
Sbjct: 540 E 540
>AC073834-2|AAX93113.1| 125|Homo sapiens unknown protein.
Length = 125
Score = 34.7 bits (76), Expect = 0.43
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +3
Query: 525 LKCADISNPCRPWSVSQKWSVKVCEEFFRQGDYEKM-LDLPVTQLCDRD 668
+ D+ +PW +S++ + V EFF QGD E++ L L + + DR+
Sbjct: 4 MTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRN 52
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,236,609
Number of Sequences: 237096
Number of extensions: 2485762
Number of successful extensions: 5460
Number of sequences better than 10.0: 228
Number of HSP's better than 10.0 without gapping: 4962
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5191
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10816958492
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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