Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP17_FL5_P09
(869 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 66 1e-10
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 64 5e-10
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 64 5e-10
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 64 5e-10
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 64 5e-10
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 64 5e-10
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 64 5e-10
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 60 8e-09
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 60 8e-09
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 60 8e-09
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 60 8e-09
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 60 8e-09
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 60 8e-09
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 60 8e-09
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 60 8e-09
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 60 1e-08
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 60 1e-08
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 60 1e-08
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 60 1e-08
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 60 1e-08
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 60 1e-08
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 60 1e-08
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 60 1e-08
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 59 2e-08
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 59 2e-08
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 59 2e-08
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 59 2e-08
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 59 2e-08
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 59 2e-08
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 59 2e-08
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 59 2e-08
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 59 2e-08
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 59 2e-08
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 59 2e-08
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 59 2e-08
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 59 2e-08
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 59 2e-08
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 59 2e-08
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 59 2e-08
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 59 2e-08
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 59 2e-08
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 58 3e-08
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 57 1e-07
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 56 1e-07
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 56 1e-07
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 56 1e-07
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 56 1e-07
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 56 1e-07
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 56 1e-07
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 56 1e-07
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 56 2e-07
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 56 2e-07
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 56 2e-07
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 56 2e-07
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 55 3e-07
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 55 3e-07
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 55 3e-07
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 55 3e-07
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 55 3e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 55 3e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 55 3e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 55 3e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 55 3e-07
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 54 5e-07
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 54 5e-07
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 54 5e-07
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 54 5e-07
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 54 5e-07
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 54 5e-07
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 54 9e-07
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 53 1e-06
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 53 1e-06
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 53 1e-06
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 53 1e-06
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 53 1e-06
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 53 1e-06
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 53 1e-06
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 53 1e-06
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 53 1e-06
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 53 1e-06
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 53 1e-06
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 53 2e-06
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 53 2e-06
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 53 2e-06
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 53 2e-06
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 53 2e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 52 2e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 52 2e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 52 3e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 52 4e-06
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 52 4e-06
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 52 4e-06
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 52 4e-06
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 51 5e-06
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 51 5e-06
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 51 5e-06
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 51 5e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 5e-06
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 51 5e-06
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 51 6e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 51 6e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 51 6e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 51 6e-06
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 51 6e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 51 6e-06
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 50 8e-06
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 50 8e-06
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 50 8e-06
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 50 8e-06
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 50 8e-06
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 50 8e-06
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 50 8e-06
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 50 8e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 50 1e-05
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 50 1e-05
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 50 1e-05
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 50 1e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 50 1e-05
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 49 2e-05
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 49 3e-05
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 49 3e-05
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 49 3e-05
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 49 3e-05
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 49 3e-05
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 49 3e-05
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 49 3e-05
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 49 3e-05
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 49 3e-05
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 48 3e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 48 6e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 48 6e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 48 6e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 47 8e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 47 8e-05
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 47 8e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 47 8e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 47 8e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 47 8e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 47 8e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 47 1e-04
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 47 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 2e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 2e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 46 2e-04
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 45 3e-04
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 44 7e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 43 0.001
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 43 0.001
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.001
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 43 0.001
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 43 0.002
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 42 0.002
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 42 0.002
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 42 0.002
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 42 0.002
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 42 0.003
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 42 0.003
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 41 0.005
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 41 0.005
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 41 0.005
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 40 0.012
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 31 4.1
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 31 7.2
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 66.5 bits (155), Expect = 1e-10
Identities = 45/168 (26%), Positives = 77/168 (45%), Gaps = 8/168 (4%)
Frame = +2
Query: 56 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 214
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 215 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 391
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 392 VSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V +NGSV + + +++ +P D Q CT KF S ++ E+D
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 181
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 64.5 bits (150), Expect = 5e-10
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 56 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 214
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 215 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 388
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 389 RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V +NGSV + + +++ +P D Q CT KF S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 64.5 bits (150), Expect = 5e-10
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 56 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 214
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 215 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 388
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 389 RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V +NGSV + + +++ +P D Q CT KF S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 64.5 bits (150), Expect = 5e-10
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 56 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 214
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 215 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 388
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 389 RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V +NGSV + + +++ +P D Q CT KF S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 64.5 bits (150), Expect = 5e-10
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 56 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 214
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 215 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 388
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 389 RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V +NGSV + + +++ +P D Q CT KF S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 64.5 bits (150), Expect = 5e-10
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 56 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 214
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 215 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 388
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 389 RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V +NGSV + + +++ +P D Q CT KF S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 64.5 bits (150), Expect = 5e-10
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Frame = +2
Query: 56 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 214
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 215 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 388
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 389 RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V +NGSV + + +++ +P D Q CT KF S ++ E+D
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEID 182
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 60.5 bits (140), Expect = 8e-09
Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V + +M + +P D Q C+ KFGS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 60.5 bits (140), Expect = 8e-09
Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +2
Query: 158 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 331
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 332 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
D+VL N A T V +NGSV + + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 509 RMHNSDEMD 535
++ E+D
Sbjct: 127 WTYDHTEID 135
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 60.5 bits (140), Expect = 8e-09
Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V + +M + +P D Q C+ KFGS ++ +D
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 147
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 60.5 bits (140), Expect = 8e-09
Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V + +M + +P D Q C+ KFGS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 60.5 bits (140), Expect = 8e-09
Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V + +M + +P D Q C+ KFGS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 60.5 bits (140), Expect = 8e-09
Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V + +M + +P D Q C+ KFGS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 60.5 bits (140), Expect = 8e-09
Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V + +M + +P D Q C+ KFGS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 60.5 bits (140), Expect = 8e-09
Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V + +M + +P D Q C+ KFGS ++ +D
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVD 182
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 60.1 bits (139), Expect = 1e-08
Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXRDXQXNI 559
V + + S+ + +P D Q C KFGS ++ ++D + +
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTV 220
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 60.1 bits (139), Expect = 1e-08
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 4/137 (2%)
Frame = +2
Query: 134 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 307
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 308 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSXIKRLDISTPISMQLDNWPNDM 481
++E +W PDVVLLN D AL VS++GSV + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 482 QTCTFKFGSRMHNSDEM 532
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 60.1 bits (139), Expect = 1e-08
Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXRDXQXNI 559
V + + S+ + +P D Q C KFGS ++ ++D + +
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTV 220
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.1 bits (139), Expect = 1e-08
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 4/137 (2%)
Frame = +2
Query: 134 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 307
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 308 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSXIKRLDISTPISMQLDNWPNDM 481
++E +W PDVVLLN D AL VS++GSV + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 482 QTCTFKFGSRMHNSDEM 532
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 59.7 bits (138), Expect = 1e-08
Identities = 36/150 (24%), Positives = 70/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 104 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 268
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 269 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 445
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 446 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + +P D+Q C+ KFGS ++ ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 59.7 bits (138), Expect = 1e-08
Identities = 36/150 (24%), Positives = 70/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 104 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 268
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 269 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 445
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 446 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + +P D+Q C+ KFGS ++ ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 59.7 bits (138), Expect = 1e-08
Identities = 36/150 (24%), Positives = 70/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 104 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 268
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 269 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 445
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 446 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + +P D+Q C+ KFGS ++ ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 59.7 bits (138), Expect = 1e-08
Identities = 36/150 (24%), Positives = 70/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 104 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 268
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 269 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 445
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 446 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + +P D+Q C+ KFGS ++ ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 186
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 157
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 186
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 188
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 187
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 59.3 bits (137), Expect = 2e-08
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 409
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 182
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Frame = +2
Query: 77 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 241
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 242 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 406
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + M + +P D Q C+ KFGS ++ E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Frame = +2
Query: 77 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 241
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 242 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 406
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + M + +P D Q C+ KFGS ++ E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/139 (31%), Positives = 70/139 (50%), Gaps = 6/139 (4%)
Frame = +2
Query: 134 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 307
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 308 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSXIKRLDISTPISMQLDNWPN 475
++E +W PDVVLLN G++ + VS++GSV + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 476 DMQTCTFKFGSRMHNSDEM 532
D Q CT F S ++S E+
Sbjct: 161 DWQNCTMVFSSYSYDSSEV 179
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Frame = +2
Query: 77 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 241
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 242 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 406
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + M + +P D Q C+ KFGS ++ E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 58.8 bits (136), Expect = 2e-08
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Frame = +2
Query: 77 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 241
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 242 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 406
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + M + +P D Q C+ KFGS ++ E+D
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEID 187
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 58.4 bits (135), Expect = 3e-08
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 104 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 268
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 269 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 445
WN ++G V S+ W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 446 ISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + +P D+Q C+ KFGS ++ ++D
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVD 199
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 56.8 bits (131), Expect = 1e-07
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 400
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 401 NGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
G V+ I + + + +P D Q CT KFGS ++ ++D
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKID 185
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/154 (26%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 104 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 268
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 269 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 433
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 434 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ S+ + +P D Q CT KFGS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/154 (26%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 104 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 268
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 269 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 433
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 434 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ S+ + +P D Q CT KFGS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/154 (26%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 104 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 268
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 269 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 433
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 434 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ S+ + +P D Q CT KFGS ++ ++D
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 165
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/154 (26%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 104 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 268
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 269 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 433
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 434 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ S+ + +P D Q CT KFGS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/154 (26%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 104 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 268
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 269 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 433
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 434 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ S+ + +P D Q CT KFGS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/154 (26%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 104 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 268
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 269 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 433
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 434 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ S+ + +P D Q CT KFGS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/154 (26%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Frame = +2
Query: 104 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 268
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 269 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 433
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 434 ISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ S+ + +P D Q CT KFGS ++ ++D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 190
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/133 (25%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
Frame = +2
Query: 146 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 319
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 320 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTF 496
+W P++VL N G Y V GSV+ + + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 497 KFGSRMHNSDEMD 535
F S+ +N++E++
Sbjct: 165 IFRSQTYNAEEVE 177
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/133 (25%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
Frame = +2
Query: 146 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 319
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 320 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTF 496
+W P++VL N G Y V GSV+ + + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 497 KFGSRMHNSDEMD 535
F S+ +N++E++
Sbjct: 165 IFRSQTYNAEEVE 177
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 55.6 bits (128), Expect = 2e-07
Identities = 42/152 (27%), Positives = 72/152 (47%), Gaps = 8/152 (5%)
Frame = +2
Query: 104 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 268
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 269 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSXIKRLDIS 439
W+ ++ G V S +WRPD+VL N + AL V S +G + +
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 440 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 55.6 bits (128), Expect = 2e-07
Identities = 42/152 (27%), Positives = 72/152 (47%), Gaps = 8/152 (5%)
Frame = +2
Query: 104 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 268
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 269 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSXIKRLDIS 439
W+ ++ G V S +WRPD+VL N + AL V S +G + +
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 440 TPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ S+ + +P D Q C+ F S+ ++++E+D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 55.2 bits (127), Expect = 3e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 412
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 413 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 55.2 bits (127), Expect = 3e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 412
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 413 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 119
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 55.2 bits (127), Expect = 3e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 412
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 413 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 55.2 bits (127), Expect = 3e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 412
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 413 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 55.2 bits (127), Expect = 3e-07
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 412
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 413 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/167 (26%), Positives = 73/167 (43%), Gaps = 10/167 (5%)
Frame = +2
Query: 71 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 235
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 236 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 400
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 401 NGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXR 541
+G+V + + + +P D Q C FGS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/167 (26%), Positives = 73/167 (43%), Gaps = 10/167 (5%)
Frame = +2
Query: 71 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 235
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 236 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 400
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 401 NGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXR 541
+G+V + + + +P D Q C FGS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/167 (26%), Positives = 73/167 (43%), Gaps = 10/167 (5%)
Frame = +2
Query: 71 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 235
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 236 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 400
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 401 NGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXR 541
+G+V + + + +P D Q C FGS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/167 (26%), Positives = 73/167 (43%), Gaps = 10/167 (5%)
Frame = +2
Query: 71 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 235
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 236 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 400
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 401 NGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXR 541
+G+V + + + +P D Q C FGS H ++D R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +2
Query: 68 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 235
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 236 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 406
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +2
Query: 68 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 235
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 236 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 406
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +2
Query: 68 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 235
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 236 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 406
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +2
Query: 68 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 235
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 236 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 406
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +2
Query: 68 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 235
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 236 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 406
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + + + +P D Q C FGS +N +++D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +2
Query: 68 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 235
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 236 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 406
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 53.6 bits (123), Expect = 9e-07
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 412
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 413 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
K + +++ ++ + +P D Q CTF F S ++ D M
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSM 190
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = +2
Query: 158 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 331
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 332 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 509 RMHNSDEMD 535
++ E+D
Sbjct: 176 WTYDRTEID 184
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = +2
Query: 158 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 331
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 332 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 509 RMHNSDEMD 535
++ E+D
Sbjct: 176 WTYDRTEID 184
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = +2
Query: 158 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 331
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 332 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 509 RMHNSDEMD 535
++ E+D
Sbjct: 176 WTYDRTEID 184
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = +2
Query: 158 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 331
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 332 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 509 RMHNSDEMD 535
++ E+D
Sbjct: 176 WTYDRTEID 184
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = +2
Query: 158 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 331
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 332 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 509 RMHNSDEMD 535
++ E+D
Sbjct: 176 WTYDRTEID 184
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Frame = +2
Query: 230 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 406
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Frame = +2
Query: 230 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 406
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
+ K + + + ++ + +P D Q CT F S ++ D M
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 175
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = +2
Query: 158 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 331
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 332 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 509 RMHNSDEMD 535
++ E+D
Sbjct: 176 WTYDRTEID 184
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = +2
Query: 158 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 331
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 332 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 509 RMHNSDEMD 535
++ E+D
Sbjct: 176 WTYDRTEID 184
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 412
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 413 SXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
K + +++ + + +P D Q CTF F S ++ D M
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSM 190
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = +2
Query: 158 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 331
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 332 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
DVVL N A + A VS +GS+ + + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 509 RMHNSDEMD 535
++ E+D
Sbjct: 176 WTYDRTEID 184
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 155 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 331
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 332 DVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFK 499
D+VL N A GD+A+ + + G ++ + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 500 FGS 508
G+
Sbjct: 166 LGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 155 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 331
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 332 DVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFK 499
D+VL N A GD+A+ + + G ++ + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 500 FGS 508
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 155 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 331
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 332 DVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFK 499
D+VL N A GD+A+ + + G ++ + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 500 FGS 508
G+
Sbjct: 166 LGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 155 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 331
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 332 DVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFK 499
D+VL N A GD+A+ + + G ++ + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 500 FGS 508
G+
Sbjct: 166 LGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Frame = +2
Query: 155 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRP 331
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 332 DVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFK 499
D+VL N A GD+A+ + + G ++ + + + ++P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 500 FGS 508
G+
Sbjct: 166 LGT 168
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/100 (27%), Positives = 48/100 (48%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 415
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 416 XIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
L T + +L ++P D C+ F + + + E++
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELE 185
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/100 (27%), Positives = 48/100 (48%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 415
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 416 XIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
L T + +L ++P D C+ F + + + E++
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELE 185
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 52.0 bits (119), Expect = 3e-06
Identities = 27/100 (27%), Positives = 48/100 (48%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 415
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 416 XIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
L T + +L ++P D C+ F + + + E++
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELE 185
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 128 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 289
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 290 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDN 466
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 467 WPNDMQTCTFKFGSRMHNSDEM 532
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 128 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 289
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 290 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDN 466
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 467 WPNDMQTCTFKFGSRMHNSDEM 532
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 128 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 289
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 290 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDN 466
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 467 WPNDMQTCTFKFGSRMHNSDEM 532
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 128 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 289
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 290 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDN 466
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 467 WPNDMQTCTFKFGSRMHNSDEM 532
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 51.2 bits (117), Expect = 5e-06
Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 80 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 247
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 248 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 418
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 419 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
RL IS MQL+++P D C KFGS + + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 51.2 bits (117), Expect = 5e-06
Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 80 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 247
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 248 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 418
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 419 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
RL IS MQL+++P D C KFGS + + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 51.2 bits (117), Expect = 5e-06
Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 80 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 247
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 248 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 418
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 419 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
RL IS MQL+++P D C KFGS + + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 51.2 bits (117), Expect = 5e-06
Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 80 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 247
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 248 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 418
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 419 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
RL IS MQL+++P D C KFGS + + E+
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEV 201
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 51.2 bits (117), Expect = 5e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 415
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 416 XIKRLDISTPISMQLDNWPNDMQTCTFKF 502
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 51.2 bits (117), Expect = 5e-06
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 1/111 (0%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 370
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 371 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNS 523
+ + G V K L + T S+ + N+P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 50.8 bits (116), Expect = 6e-06
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 409
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXRDXQXNI 559
+ + + + +P D+Q C KFGS + +D + + +I
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADI 164
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 50.8 bits (116), Expect = 6e-06
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 409
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXRDXQXNI 559
+ + + + +P D+Q C KFGS + +D + + +I
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADI 187
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 50.8 bits (116), Expect = 6e-06
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 409
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXRDXQXNI 559
+ + + + +P D+Q C KFGS + +D + + +I
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADI 187
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 50.8 bits (116), Expect = 6e-06
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 409
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXRDXQXNI 559
+ + + + +P D+Q C KFGS + +D + + +I
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADI 187
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 50.8 bits (116), Expect = 6e-06
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 370
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 371 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 50.8 bits (116), Expect = 6e-06
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 409
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXRDXQXNI 559
+ + + + +P D+Q C KFGS + +D + + +I
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADI 187
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 370
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 371 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 370
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 371 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 192
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 370
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 371 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 370
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 371 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 370
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 371 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 370
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 371 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 370
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 371 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 370
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 371 DYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ + G V K L + T S+ + N+P D+Q C+ F S +H +++
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDIN 186
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 80 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 247
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 248 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 418
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 419 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 409
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXRDXQXNI 559
+ + + + +P D+Q C KFGS + +D + + +I
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADI 187
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 80 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 247
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 248 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 418
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 419 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Frame = +2
Query: 236 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 409
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 410 VSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXRDXQXNI 559
+ + + + +P D+Q C KFGS + +D + + +I
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADI 187
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 80 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 247
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 248 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 418
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 419 IKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/168 (23%), Positives = 71/168 (42%), Gaps = 7/168 (4%)
Frame = +2
Query: 53 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 220
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 221 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 391
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 392 VSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ +G+V R+ + M L +P D Q CT + S + +D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/158 (24%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 89 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 256
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 257 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 427
RL +N+ + +W PD + N+ A R+ N+G + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 428 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXR 541
L I+ +QL N+P D +C F S + +EM R
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYR 202
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 48.8 bits (111), Expect = 3e-05
Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 7/168 (4%)
Frame = +2
Query: 53 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 220
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 221 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 391
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 392 VSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ +G+V R+ + M L +P D Q CT + S + +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 48.8 bits (111), Expect = 3e-05
Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 7/168 (4%)
Frame = +2
Query: 53 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 220
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 221 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 391
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 392 VSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ +G+V R+ + M L +P D Q CT + S + +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 48.8 bits (111), Expect = 3e-05
Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 7/168 (4%)
Frame = +2
Query: 53 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 220
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 221 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 391
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 392 VSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ +G+V R+ + M L +P D Q CT + S + +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.8 bits (111), Expect = 3e-05
Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 7/168 (4%)
Frame = +2
Query: 53 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 220
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 221 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 391
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 392 VSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ +G+V R+ + M L +P D Q CT + S + +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.8 bits (111), Expect = 3e-05
Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 7/168 (4%)
Frame = +2
Query: 53 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 220
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 221 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 391
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 392 VSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ +G+V R+ + M L +P D Q CT + S + +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.8 bits (111), Expect = 3e-05
Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 7/168 (4%)
Frame = +2
Query: 53 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 220
CA S + N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CA-QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY 81
Query: 221 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 391
+ Q W DKRLS+N + +++LW PD LN + ++ R
Sbjct: 82 TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 141
Query: 392 VSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ +G+V R+ + M L +P D Q CT + S + +D+++
Sbjct: 142 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/158 (24%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 89 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 256
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 257 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 427
RL +N+ + +W PD + N+ A R+ N+G + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 428 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXR 541
L I+ +QL N+P D +C F S + +EM R
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYR 202
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/158 (24%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 89 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 256
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 257 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 427
RL +N+ + +W PD + N+ A R+ N+G + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 428 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXR 541
L I+ +QL N+P D +C F S + +EM R
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYR 184
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 48.4 bits (110), Expect = 3e-05
Identities = 39/168 (23%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 53 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 220
C S E N + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 221 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 391
+ Q +W DKRLS++ + +++LW PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 392 VSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ +G+V R+ + M L +P D Q CT + S + +D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 47.6 bits (108), Expect = 6e-05
Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 47.6 bits (108), Expect = 6e-05
Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 47.6 bits (108), Expect = 6e-05
Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 47.2 bits (107), Expect = 8e-05
Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Frame = +2
Query: 92 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 259
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 260 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 430
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 431 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 47.2 bits (107), Expect = 8e-05
Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Frame = +2
Query: 92 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 259
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 260 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 430
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 431 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 47.2 bits (107), Expect = 8e-05
Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Frame = +2
Query: 92 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 259
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 260 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 430
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 431 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 47.2 bits (107), Expect = 8e-05
Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Frame = +2
Query: 92 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 259
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 260 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 430
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 431 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 47.2 bits (107), Expect = 8e-05
Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Frame = +2
Query: 92 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 259
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 260 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 430
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 431 DISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
I+ M+L N+P D C KFGS + E+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEI 184
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 46.8 bits (106), Expect = 1e-04
Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 3/113 (2%)
Frame = +2
Query: 203 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 382
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 383 RA---RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
R+ NG++ RL IS M+L ++P D C KFGS + EM
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 46.8 bits (106), Expect = 1e-04
Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 3/113 (2%)
Frame = +2
Query: 203 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 382
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 383 RA---RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
R+ NG++ RL IS M+L ++P D C KFGS + EM
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 56 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 214
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 215 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 376
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 56 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 214
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 215 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 376
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 77 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 244
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 245 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 415
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 416 XIKRLDISTPISMQLDNWPNDMQTC 490
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 77 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 244
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 245 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 415
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 416 XIKRLDISTPISMQLDNWPNDMQTC 490
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 107 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 274
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 275 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 445
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 446 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 107 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 274
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 275 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 445
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 446 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 77 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 244
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 245 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 415
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 416 XIKRLDISTPISMQLDNWPNDMQTC 490
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 77 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 244
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 245 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 415
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 416 XIKRLDISTPISMQLDNWPNDMQTC 490
RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 107 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 274
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 275 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 445
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 446 ISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 45.2 bits (102), Expect = 3e-04
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
Frame = +2
Query: 104 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 268
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 269 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT 361
W+ ++ G V S +WRPD+VL N + T
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQT 120
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 44.0 bits (99), Expect = 7e-04
Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 7/168 (4%)
Frame = +2
Query: 53 CAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTV 220
C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 23 CCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDY 82
Query: 221 RILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---AR 391
+ Q +W DKRLS++ + +++L PD LN + ++ R
Sbjct: 83 TLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRMIR 142
Query: 392 VSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+ +G+V R+ + M L +P D Q CT + S + +D+++
Sbjct: 143 LHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
Frame = +2
Query: 74 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 238
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 239 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 406
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+V R+ + +M L +P D QTC + S ++ ++++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
Frame = +2
Query: 74 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 238
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 239 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 406
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+V R+ + +M L +P D QTC + S ++ ++++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
Frame = +2
Query: 74 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 238
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 239 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 406
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+V R+ + +M L +P D QTC + S ++ ++++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
Frame = +2
Query: 74 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 238
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 239 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 406
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+V R+ + +M L +P D QTC + S ++ ++++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
Frame = +2
Query: 74 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 238
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 239 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 406
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+V R+ + +M L +P D QTC + S ++ ++++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 43.2 bits (97), Expect = 0.001
Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 9/155 (5%)
Frame = +2
Query: 95 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 256
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 257 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSXIKR 427
+RL +N+ ++W PD N+ A R+ N+G V R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 428 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
L I +QL N+P D +C +F S + +E+
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 43.2 bits (97), Expect = 0.001
Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 9/155 (5%)
Frame = +2
Query: 95 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 256
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 257 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSXIKR 427
+RL +N+ ++W PD N+ A R+ N+G V R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 428 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
L I +QL N+P D +C +F S + +E+
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 43.2 bits (97), Expect = 0.001
Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 9/155 (5%)
Frame = +2
Query: 95 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 256
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 257 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSXIKR 427
+RL +N+ ++W PD N+ A R+ N+G V R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 428 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
L I +QL N+P D +C +F S + +E+
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 43.2 bits (97), Expect = 0.001
Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 9/155 (5%)
Frame = +2
Query: 95 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 256
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 257 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSXIKR 427
+RL +N+ ++W PD N+ A R+ N+G V R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 428 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
L I +QL N+P D +C +F S + +E+
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/163 (23%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
Frame = +2
Query: 74 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 238
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 239 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 406
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 407 SVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
+V R+ + +M L +P D QTC + S ++ ++++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVE 189
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 42.7 bits (96), Expect = 0.002
Identities = 37/158 (23%), Positives = 69/158 (43%), Gaps = 9/158 (5%)
Frame = +2
Query: 95 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHANIRES---ESTVRILADLQMNWID 256
++ +++SLL YD + PD + V+ +++ + E T+ I+ W D
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDII--FAQTWFD 121
Query: 257 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 427
RL +N+ ++W PD N+ + A R+ N+G V R
Sbjct: 122 SRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
Query: 428 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMDXR 541
L I+ +QL N+P D +C +F S + +E++ +
Sbjct: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYK 219
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 370
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 371 DYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
+ R+S NG+V R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 42.3 bits (95), Expect = 0.002
Identities = 38/155 (24%), Positives = 69/155 (44%), Gaps = 9/155 (5%)
Frame = +2
Query: 95 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 256
+++++++LL YD + PD + +++ +++ N E T+ I QM W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFF-AQM-WYD 123
Query: 257 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSXIKR 427
+RL +N+ ++W PD N+ A R+ N+G V R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLR 183
Query: 428 LDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEM 532
L I +QL N+P D +C +F S + +E+
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 370
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 371 DYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
+ R+S NG+V R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 194 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 370
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 371 DYALR---ARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
+ R+S NG+V R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 41.9 bits (94), Expect = 0.003
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N + R+ NG+V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 41.9 bits (94), Expect = 0.003
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N + R+ NG+V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 128 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 295
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 296 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 463
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 464 NWPNDMQTCTFKFGS 508
N+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 39.9 bits (89), Expect = 0.012
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Frame = +2
Query: 221 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 388
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 389 RVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGS 508
R+S NG+V R+ ++ M L N+P D+QTC + S
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 103
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 31.5 bits (68), Expect = 4.1
Identities = 18/72 (25%), Positives = 32/72 (44%)
Frame = +2
Query: 320 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFK 499
LW +A A + +A + ++G V + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 500 FGSRMHNSDEMD 535
FGS ++ ++D
Sbjct: 85 FGSWTYDKAKID 96
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 30.7 bits (66), Expect = 7.2
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Frame = +2
Query: 368 GDYAL----RARVSNNGSVSXIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHNSDEMD 535
GD+A+ +A + ++G V + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,747,068
Number of Sequences: 237096
Number of extensions: 2424823
Number of successful extensions: 6491
Number of sequences better than 10.0: 178
Number of HSP's better than 10.0 without gapping: 5852
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6349
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11048563978
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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