Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP17_FL5_M14
(898 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 55 4e-07
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 53 2e-06
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 53 2e-06
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 53 2e-06
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 53 2e-06
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 53 2e-06
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 53 2e-06
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 50 9e-06
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 50 9e-06
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 50 9e-06
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 50 9e-06
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 50 9e-06
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 50 9e-06
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 50 9e-06
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 49 3e-05
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 48 5e-05
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 48 5e-05
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 48 6e-05
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 48 6e-05
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 48 6e-05
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 48 6e-05
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 48 6e-05
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 48 6e-05
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 47 8e-05
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 47 8e-05
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 47 8e-05
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 47 8e-05
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 47 8e-05
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 47 8e-05
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 47 8e-05
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 47 8e-05
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 47 8e-05
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 47 8e-05
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 47 8e-05
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 47 8e-05
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 47 8e-05
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 47 8e-05
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 47 8e-05
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 47 8e-05
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 47 8e-05
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 47 8e-05
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 47 8e-05
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 47 8e-05
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 47 1e-04
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 47 1e-04
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 47 1e-04
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 47 1e-04
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 47 1e-04
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 47 1e-04
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 46 1e-04
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 46 1e-04
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 46 1e-04
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 46 1e-04
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 46 2e-04
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 46 2e-04
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 46 2e-04
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 46 2e-04
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 46 2e-04
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 46 2e-04
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 46 2e-04
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 46 2e-04
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 45 3e-04
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 45 3e-04
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 45 3e-04
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 45 3e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 45 3e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 45 3e-04
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 45 3e-04
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 45 4e-04
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 45 4e-04
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 44 6e-04
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 44 6e-04
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 44 6e-04
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 44 6e-04
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 44 6e-04
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 44 6e-04
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 44 6e-04
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 43 0.001
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 43 0.001
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 43 0.002
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 43 0.002
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 43 0.002
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 43 0.002
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 42 0.002
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 42 0.002
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 42 0.002
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 42 0.002
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 42 0.004
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 42 0.004
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 42 0.004
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 41 0.005
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 41 0.005
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 41 0.005
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 41 0.005
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 41 0.005
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 41 0.005
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 41 0.005
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 41 0.005
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 41 0.005
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 41 0.005
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 41 0.005
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 41 0.005
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 41 0.005
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 41 0.005
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 41 0.005
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 41 0.005
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 41 0.005
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 41 0.005
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 41 0.005
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 41 0.005
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 41 0.005
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 41 0.005
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 41 0.007
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 41 0.007
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 38 0.037
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.037
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.037
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.037
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 38 0.037
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 38 0.037
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 38 0.037
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 38 0.037
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 38 0.037
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 36 0.15
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 36 0.15
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 36 0.15
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 35 0.35
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 35 0.35
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 35 0.35
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 35 0.46
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 35 0.46
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 34 0.80
Y11354-1|CAA72189.1| 1083|Homo sapiens subunit of RNA polymerase... 31 4.3
AY623115-1|AAT38111.1| 1085|Homo sapiens TAF4 RNA polymerase II,... 31 4.3
AL137077-2|CAI11045.1| 1085|Homo sapiens TAF4 RNA polymerase II,... 31 4.3
AL109911-2|CAI19182.1| 1085|Homo sapiens TAF4 RNA polymerase II,... 31 4.3
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 54.8 bits (126), Expect = 4e-07
Identities = 40/157 (25%), Positives = 67/157 (42%), Gaps = 8/157 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 427
+ L+ W D RL WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 428 VSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V +NGSV + + + + +P D CT F
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 170
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/158 (25%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRA 424
+ L+ W D RL WN+ + G + + ++R+W PD+VL NA T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V +NGSV + + + + +P D CT F
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/158 (25%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRA 424
+ L+ W D RL WN+ + G + + ++R+W PD+VL NA T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V +NGSV + + + + +P D CT F
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/158 (25%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRA 424
+ L+ W D RL WN+ + G + + ++R+W PD+VL NA T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V +NGSV + + + + +P D CT F
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/158 (25%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRA 424
+ L+ W D RL WN+ + G + + ++R+W PD+VL NA T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V +NGSV + + + + +P D CT F
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/158 (25%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRA 424
+ L+ W D RL WN+ + G + + ++R+W PD+VL NA T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V +NGSV + + + + +P D CT F
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 52.8 bits (121), Expect = 2e-06
Identities = 41/158 (25%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRA 424
+ L+ W D RL WN+ + G + + ++R+W PD+VL NA T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V +NGSV + + + + +P D CT F
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 171
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V + +M + +P D C+ F
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKF 171
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V + +M + +P D C+ F
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKF 136
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V + +M + +P D C+ F
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKF 171
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V + +M + +P D C+ F
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKF 171
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V + +M + +P D C+ F
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKF 171
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V + +M + +P D C+ F
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKF 171
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++ G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V + +M + +P D C+ F
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKF 171
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 3/118 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRP 367
I + L L L ++ E + + L+ W D RL WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 368 DVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
D+VL NA T V +NGSV + + + + +P D CT F
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKF 124
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 48.0 bits (109), Expect = 5e-05
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G T L V SE +W PD+VL NA A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V + + S+ + +P D C F
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKF 201
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 48.0 bits (109), Expect = 5e-05
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G T L V SE +W PD+VL NA A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V + + S+ + +P D C F
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKF 201
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 47.6 bits (108), Expect = 6e-05
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 6/139 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLX 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAXEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSCIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMXLDXWPNDMXTCTFXF 538
++ + +P D+ C+ F
Sbjct: 170 CTIDVTFFPFDLQNCSMKF 188
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 47.6 bits (108), Expect = 6e-05
Identities = 40/127 (31%), Positives = 60/127 (47%), Gaps = 4/127 (3%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RL W+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSCIKRLDISTPISMXLDXWPNDM 517
++E +W PDVVLLN D AL VS++GSV + S+ + +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 518 XTCTFXF 538
CT F
Sbjct: 163 QNCTMVF 169
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 47.6 bits (108), Expect = 6e-05
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 6/139 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLX 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAXEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSCIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMXLDXWPNDMXTCTFXF 538
++ + +P D+ C+ F
Sbjct: 170 CTIDVTFFPFDLQNCSMKF 188
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 47.6 bits (108), Expect = 6e-05
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 6/139 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLX 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAXEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSCIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMXLDXWPNDMXTCTFXF 538
++ + +P D+ C+ F
Sbjct: 170 CTIDVTFFPFDLQNCSMKF 188
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 47.6 bits (108), Expect = 6e-05
Identities = 40/127 (31%), Positives = 60/127 (47%), Gaps = 4/127 (3%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RL W+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSCIKRLDISTPISMXLDXWPNDM 517
++E +W PDVVLLN D AL VS++GSV + S+ + +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 518 XTCTFXF 538
CT F
Sbjct: 163 QNCTMVF 169
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 47.6 bits (108), Expect = 6e-05
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 6/139 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLX 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAXEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSCIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMXLDXWPNDMXTCTFXF 538
++ + +P D+ C+ F
Sbjct: 170 CTIDVTFFPFDLQNCSMKF 188
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 47.2 bits (107), Expect = 8e-05
Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 10/152 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
++ + M + +P D C+ F
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKF 176
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 175
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 146
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 47.2 bits (107), Expect = 8e-05
Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 10/152 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
++ + M + +P D C+ F
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKF 176
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 176
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 175
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 177
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 177
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 47.2 bits (107), Expect = 8e-05
Identities = 26/89 (29%), Positives = 39/89 (43%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 CIKRLDISTPISMXLDXWPNDMXTCTFXF 538
L T + L +P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 176
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 47.2 bits (107), Expect = 8e-05
Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 10/152 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
++ + M + +P D C+ F
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKF 176
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 177
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 177
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 177
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 177
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 47.2 bits (107), Expect = 8e-05
Identities = 26/89 (29%), Positives = 39/89 (43%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 452 CIKRLDISTPISMXLDXWPNDMXTCTFXF 538
L T + L +P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 176
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 47.2 bits (107), Expect = 8e-05
Identities = 26/89 (29%), Positives = 39/89 (43%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 CIKRLDISTPISMXLDXWPNDMXTCTFXF 538
L T + L +P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 47.2 bits (107), Expect = 8e-05
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 446 VSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
V+ I + + + +P D CT F
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 171
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 47.2 bits (107), Expect = 8e-05
Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 10/152 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
++ + M + +P D C+ F
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKF 176
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 46.8 bits (106), Expect = 1e-04
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL 418
D+VL N A GD+A+
Sbjct: 109 DLVLYNNA---DGDFAI 122
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 46.8 bits (106), Expect = 1e-04
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL 418
D+VL N A GD+A+
Sbjct: 109 DLVLYNNA---DGDFAI 122
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 46.8 bits (106), Expect = 1e-04
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL 418
D+VL N A GD+A+
Sbjct: 109 DLVLYNNA---DGDFAI 122
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 46.8 bits (106), Expect = 1e-04
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL 418
D+VL N A GD+A+
Sbjct: 109 DLVLYNNA---DGDFAI 122
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 46.8 bits (106), Expect = 1e-04
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +2
Query: 191 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRP 367
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 368 DVVLLNAAATTAGDYAL 418
D+VL N A GD+A+
Sbjct: 109 DLVLYNNA---DGDFAI 122
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 46.8 bits (106), Expect = 1e-04
Identities = 26/89 (29%), Positives = 39/89 (43%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 CIKRLDISTPISMXLDXWPNDMXTCTFXF 538
L T + L +P D C+ F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSF 174
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/141 (26%), Positives = 62/141 (43%), Gaps = 8/141 (5%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLX 304
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSCIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL VS +G + +
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMXLDXWPNDMXTCTFXF 538
+ S+ + +P D C+ F
Sbjct: 151 SACSISVTYFPFDWQNCSLIF 171
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/139 (22%), Positives = 60/139 (43%), Gaps = 6/139 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLX 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAXEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSCIKRLDISTP 481
WN ++G V S+ W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMXLDXWPNDMXTCTFXF 538
++ + +P D+ C+ F
Sbjct: 170 CTIDVTFFPFDLQNCSMKF 188
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/129 (29%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RL W+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSCIKRLDISTPISMXLDXWPN 511
++E +W PDVVLLN G++ + VS++GSV + S+ + +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 512 DMXTCTFXF 538
D CT F
Sbjct: 161 DWQNCTMVF 169
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/141 (26%), Positives = 62/141 (43%), Gaps = 8/141 (5%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLX 304
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSCIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL VS +G + +
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMXLDXWPNDMXTCTFXF 538
+ S+ + +P D C+ F
Sbjct: 151 SACSISVTYFPFDWQNCSLIF 171
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 7/172 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDIST 478
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 479 PISMXLDXWPNDMXTCTFXFXFXGWXXXXTKWXXXIDXRXXPPCLDFXXGGD 634
S+ + +P D CT F W K ++ LDF G+
Sbjct: 160 SCSIDVTFFPFDQQNCT--MKFGSWTYDKAK-IDLVNMHSRVDQLDFWESGE 208
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 7/172 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDIST 478
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 479 PISMXLDXWPNDMXTCTFXFXFXGWXXXXTKWXXXIDXRXXPPCLDFXXGGD 634
S+ + +P D CT F W K ++ LDF G+
Sbjct: 160 SCSIDVTFFPFDQQNCT--MKFGSWTYDKAK-IDLVNMHSRVDQLDFWESGE 208
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 7/172 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 305 WNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDIST 478
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V +
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 134
Query: 479 PISMXLDXWPNDMXTCTFXFXFXGWXXXXTKWXXXIDXRXXPPCLDFXXGGD 634
S+ + +P D CT F W K ++ LDF G+
Sbjct: 135 SCSIDVTFFPFDQQNCT--MKFGSWTYDKAK-IDLVNMHSRVDQLDFWESGE 183
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 7/172 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDIST 478
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 479 PISMXLDXWPNDMXTCTFXFXFXGWXXXXTKWXXXIDXRXXPPCLDFXXGGD 634
S+ + +P D CT F W K ++ LDF G+
Sbjct: 160 SCSIDVTFFPFDQQNCT--MKFGSWTYDKAK-IDLVNMHSRVDQLDFWESGE 208
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 7/172 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDIST 478
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 479 PISMXLDXWPNDMXTCTFXFXFXGWXXXXTKWXXXIDXRXXPPCLDFXXGGD 634
S+ + +P D CT F W K ++ LDF G+
Sbjct: 160 SCSIDVTFFPFDQQNCT--MKFGSWTYDKAK-IDLVNMHSRVDQLDFWESGE 208
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 7/172 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDIST 478
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 479 PISMXLDXWPNDMXTCTFXFXFXGWXXXXTKWXXXIDXRXXPPCLDFXXGGD 634
S+ + +P D CT F W K ++ LDF G+
Sbjct: 160 SCSIDVTFFPFDQQNCT--MKFGSWTYDKAK-IDLVNMHSRVDQLDFWESGE 208
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLX 304
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 305 WNAXEW-GCSTWLVSSERLWRPDVVLLNAAAT 397
W+ ++ G V S +WRPD+VL N + T
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQT 120
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 7/172 (4%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAXEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDIST 478
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 479 PISMXLDXWPNDMXTCTFXFXFXGWXXXXTKWXXXIDXRXXPPCLDFXXGGD 634
S+ + +P D CT F W K ++ LDF G+
Sbjct: 160 SCSIDVTFFPFDQQNCT--MKFGSWTYDKAK-IDLVNMHSRVDQLDFWESGE 208
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + + WN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 449 SCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
K + + + ++ + +P D CT F
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTF 180
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + + WN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 449 SCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
K + + + ++ + +P D CT F
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTF 109
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + + WN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
K + + + ++ + +P D CT F
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTF 195
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + + WN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
K + + + ++ + +P D CT F
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTF 195
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 45.2 bits (102), Expect = 3e-04
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W D RL WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 45.2 bits (102), Expect = 3e-04
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W D RL WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + + WN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
K + + + ++ + +P D CT F
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTF 195
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 44.8 bits (101), Expect = 4e-04
Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 5/94 (5%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 436
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNA---VGDFQVTTKTKALLKY 140
Query: 437 NGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
G V+ I + + + +P D CT F
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKF 174
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 44.8 bits (101), Expect = 4e-04
Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W + + WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
K + +++ ++ + +P D CTF F
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTF 180
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 44.4 bits (100), Expect = 6e-04
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAA 391
++ W D L W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 44.4 bits (100), Expect = 6e-04
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAA 391
++ W D L W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 44.4 bits (100), Expect = 6e-04
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAA 391
++ W D L W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 44.4 bits (100), Expect = 6e-04
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAA 391
++ W D L W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 44.4 bits (100), Expect = 6e-04
Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W + + WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
K + +++ + + +P D CTF F
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTF 180
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 44.4 bits (100), Expect = 6e-04
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 272 -LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAA 391
++ W D L W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 117
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 44.4 bits (100), Expect = 6e-04
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +2
Query: 104 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 271
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 272 -LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAA 391
++ W D L W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 43.2 bits (97), Expect = 0.001
Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +2
Query: 266 ADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 442
A L + W + + WN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
+ K + + + ++ + +P D CT F
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTF 180
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 43.2 bits (97), Expect = 0.001
Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +2
Query: 266 ADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 442
A L + W + + WN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
+ K + + + ++ + +P D CT F
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTF 165
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDX 502
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMXTCTFXF 538
+P D C+ F
Sbjct: 158 FPFDWQNCSLKF 169
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDX 502
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMXTCTFXF 538
+P D C+ F
Sbjct: 158 FPFDWQNCSLKF 169
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDX 502
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMXTCTFXF 538
+P D C+ F
Sbjct: 158 FPFDWQNCSLKF 169
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDX 502
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMXTCTFXF 538
+P D C+ F
Sbjct: 158 FPFDWQNCSLKF 169
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 42.3 bits (95), Expect = 0.002
Identities = 35/154 (22%), Positives = 59/154 (38%), Gaps = 7/154 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLXWNAXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL + + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 CIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
RL + S+ L +P D C G+
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGY 206
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 42.3 bits (95), Expect = 0.002
Identities = 35/154 (22%), Positives = 59/154 (38%), Gaps = 7/154 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLXWNAXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL + + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 CIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
RL + S+ L +P D C G+
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGY 206
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 42.3 bits (95), Expect = 0.002
Identities = 35/154 (22%), Positives = 59/154 (38%), Gaps = 7/154 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLXWNAXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL + + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 CIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
RL + S+ L +P D C G+
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGY 206
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 42.3 bits (95), Expect = 0.002
Identities = 35/154 (22%), Positives = 59/154 (38%), Gaps = 7/154 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 281 NWIDKRLXWNAXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL + + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 452 CIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
RL + S+ L +P D C G+
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQACNLVVESYGY 201
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 41.5 bits (93), Expect = 0.004
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TCT G+
Sbjct: 178 NFPMDVQTCTMQLESFGY 195
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 41.5 bits (93), Expect = 0.004
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TCT G+
Sbjct: 178 NFPMDVQTCTMQLESFGY 195
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 41.5 bits (93), Expect = 0.004
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TCT G+
Sbjct: 178 NFPMDVQTCTMQLESFGY 195
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
LQM+W D L WN E+ G T ++W+PD++L N +A D V N S
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYN-SADERFDATFHTNVLVNSSG 113
Query: 449 SC 454
C
Sbjct: 114 HC 115
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
LQM+W D L WN E+ G T ++W+PD++L N +A D V N S
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYN-SADERFDATFHTNVLVNSSG 136
Query: 449 SC 454
C
Sbjct: 137 HC 138
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 3/118 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
DVVL NA + A VS +GS+ + + + + +P D CT F
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
LQM+W D L WN E+ G T ++W+PD++L N +A D V N S
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYN-SADERFDATFHTNVLVNSSG 136
Query: 449 SC 454
C
Sbjct: 137 HC 138
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 3/118 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
DVVL NA + A VS +GS+ + + + + +P D CT F
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TCT G+
Sbjct: 178 NFPMDVQTCTMQLESFGY 195
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TCT G+
Sbjct: 178 NFPMDVQTCTMQLESFGY 195
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 3/118 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
DVVL NA + A VS +GS+ + + + + +P D CT F
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
LQM+W D L WN E+ G T ++W+PD++L N +A D V N S
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYN-SADERFDATFHTNVLVNSSG 136
Query: 449 SC 454
C
Sbjct: 137 HC 138
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 3/118 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
DVVL NA + A VS +GS+ + + + + +P D CT F
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 3/118 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
DVVL NA + A VS +GS+ + + + + +P D CT F
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TCT G+
Sbjct: 178 NFPMDVQTCTMQLESFGY 195
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TCT G+
Sbjct: 178 NFPMDVQTCTMQLESFGY 195
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 3/118 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
DVVL NA + A VS +GS+ + + + + +P D CT F
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
LQM+W D L WN E+ G T ++W+PD++L N +A D V N S
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYN-SADERFDATFHTNVLVNSSG 136
Query: 449 SC 454
C
Sbjct: 137 HC 138
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/124 (28%), Positives = 57/124 (45%), Gaps = 10/124 (8%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLXWNAXEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSV 448
+G+V
Sbjct: 139 DGAV 142
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/124 (28%), Positives = 57/124 (45%), Gaps = 10/124 (8%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLXWNAXEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSV 448
+G+V
Sbjct: 139 DGAV 142
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 3/118 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
DVVL NA + A VS +GS+ + + + + +P D CT F
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/124 (28%), Positives = 57/124 (45%), Gaps = 10/124 (8%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLXWNAXEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSV 448
+G+V
Sbjct: 139 DGAV 142
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/124 (28%), Positives = 57/124 (45%), Gaps = 10/124 (8%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLXWNAXEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSV 448
+G+V
Sbjct: 139 DGAV 142
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 3/118 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLL-NAAATTAGDYALRARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXF 538
DVVL NA + A VS +GS+ + + + + +P D CT F
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKF 173
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TCT G+
Sbjct: 178 NFPMDVQTCTMQLESFGY 195
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 40.7 bits (91), Expect = 0.007
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAA 391
LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 118
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 40.7 bits (91), Expect = 0.007
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +2
Query: 272 LQMNWIDKRLXWNAXEW-GCSTWLVSSERLWRPDVVLLNAA 391
LQM+W D L WN E+ G T ++W+PD++L N+A
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA 118
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.037
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLXWNAXE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
+V R+ + +M L +P D TC G+
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGY 183
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.037
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLXWNAXE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
+V R+ + +M L +P D TC G+
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGY 183
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.037
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLXWNAXE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
+V R+ + +M L +P D TC G+
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGY 183
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.037
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLXWNAXE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
+V R+ + +M L +P D TC G+
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGY 183
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.037
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLXWNAXE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
+V R+ + +M L +P D TC G+
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGY 183
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 38.3 bits (85), Expect = 0.037
Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 7/144 (4%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLXWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RL +N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTP 481
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMXLDXWPNDMXTCTFXFXFXGW 553
M L +P D C G+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGY 187
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 38.3 bits (85), Expect = 0.037
Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 7/144 (4%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLXWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RL +N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTP 481
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMXLDXWPNDMXTCTFXFXFXGW 553
M L +P D C G+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGY 187
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 38.3 bits (85), Expect = 0.037
Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 7/144 (4%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLXWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RL +N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AXEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTP 481
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMXLDXWPNDMXTCTFXFXFXGW 553
M L +P D C G+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGY 187
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 38.3 bits (85), Expect = 0.037
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLXWNAXE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSCIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
+V R+ + +M L +P D TC G+
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGY 183
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 36.3 bits (80), Expect = 0.15
Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 4/112 (3%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLXWNAXEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W D RL +N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
+ R+S NG+V R+ ++ M L +P D+ TC G+
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 36.3 bits (80), Expect = 0.15
Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 4/112 (3%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLXWNAXEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W D RL +N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
+ R+S NG+V R+ ++ M L +P D+ TC G+
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 36.3 bits (80), Expect = 0.15
Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 4/112 (3%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLXWNAXEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W D RL +N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
+ R+S NG+V R+ ++ M L +P D+ TC G+
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 189
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 35.1 bits (77), Expect = 0.35
Identities = 33/138 (23%), Positives = 55/138 (39%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TC G+
Sbjct: 177 NFPMDVQTCIMQLESFGY 194
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 35.1 bits (77), Expect = 0.35
Identities = 33/138 (23%), Positives = 55/138 (39%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TC G+
Sbjct: 177 NFPMDVQTCIMQLESFGY 194
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 35.1 bits (77), Expect = 0.35
Identities = 33/138 (23%), Positives = 55/138 (39%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TC G+
Sbjct: 177 NFPMDVQTCIMQLESFGY 194
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 34.7 bits (76), Expect = 0.46
Identities = 33/138 (23%), Positives = 55/138 (39%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ ++I ++ R+ L+ W D RL +
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N + R+ NG+V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TCT G+
Sbjct: 137 NFPMDIQTCTMQLESFGY 154
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 34.7 bits (76), Expect = 0.46
Identities = 33/138 (23%), Positives = 55/138 (39%), Gaps = 8/138 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAXEWGCS 331
YD P+ K VN+T ++ ++I ++ R+ L+ W D RL +
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSCIKRLDISTPISMXLD 499
S + +W+PD+ N + R+ NG+V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 500 XWPNDMXTCTFXFXFXGW 553
+P D+ TCT G+
Sbjct: 137 NFPMDIQTCTMQLESFGY 154
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 33.9 bits (74), Expect = 0.80
Identities = 25/103 (24%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Frame = +2
Query: 257 RILADLQMNWIDKRLXWNAXEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 424
R+ L+ W D RL +N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 425 RVSNNGSVSCIKRLDISTPISMXLDXWPNDMXTCTFXFXFXGW 553
R+S NG+V R+ ++ M L +P D+ TC G+
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGY 106
>Y11354-1|CAA72189.1| 1083|Homo sapiens subunit of RNA polymerase II
transcription factor protein.
Length = 1083
Score = 31.5 bits (68), Expect = 4.3
Identities = 19/51 (37%), Positives = 20/51 (39%), Gaps = 2/51 (3%)
Frame = -3
Query: 803 GXPGAKXXPXPXXGVXXGGGCPGNXXXXXXAHRXXVP--PXPPXXRXRXPP 657
G PGA P P GGG P R VP P PP + R PP
Sbjct: 81 GAPGAAPEPPPAGRARPGGGGP-QRPGPPSPRRPLVPAGPAPPAAKLRPPP 130
>AY623115-1|AAT38111.1| 1085|Homo sapiens TAF4 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 135kD
protein.
Length = 1085
Score = 31.5 bits (68), Expect = 4.3
Identities = 19/51 (37%), Positives = 20/51 (39%), Gaps = 2/51 (3%)
Frame = -3
Query: 803 GXPGAKXXPXPXXGVXXGGGCPGNXXXXXXAHRXXVP--PXPPXXRXRXPP 657
G PGA P P GGG P R VP P PP + R PP
Sbjct: 81 GAPGAAPEPPPAGRARPGGGGP-QRPGPPSPRRPLVPAGPAPPAAKLRPPP 130
>AL137077-2|CAI11045.1| 1085|Homo sapiens TAF4 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 135kD
protein.
Length = 1085
Score = 31.5 bits (68), Expect = 4.3
Identities = 19/51 (37%), Positives = 20/51 (39%), Gaps = 2/51 (3%)
Frame = -3
Query: 803 GXPGAKXXPXPXXGVXXGGGCPGNXXXXXXAHRXXVP--PXPPXXRXRXPP 657
G PGA P P GGG P R VP P PP + R PP
Sbjct: 81 GAPGAAPEPPPAGRARPGGGGP-QRPGPPSPRRPLVPAGPAPPAAKLRPPP 130
>AL109911-2|CAI19182.1| 1085|Homo sapiens TAF4 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 135kD
protein.
Length = 1085
Score = 31.5 bits (68), Expect = 4.3
Identities = 19/51 (37%), Positives = 20/51 (39%), Gaps = 2/51 (3%)
Frame = -3
Query: 803 GXPGAKXXPXPXXGVXXGGGCPGNXXXXXXAHRXXVP--PXPPXXRXRXPP 657
G PGA P P GGG P R VP P PP + R PP
Sbjct: 81 GAPGAAPEPPPAGRARPGGGGP-QRPGPPSPRRPLVPAGPAPPAAKLRPPP 130
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,668,655
Number of Sequences: 237096
Number of extensions: 2247836
Number of successful extensions: 4734
Number of sequences better than 10.0: 136
Number of HSP's better than 10.0 without gapping: 4394
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4659
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11548247776
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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