Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP17_FL5_L11
(851 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 70 1e-11
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 68 5e-11
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 68 5e-11
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 68 5e-11
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 68 5e-11
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 68 5e-11
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 68 5e-11
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 64 6e-10
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 64 6e-10
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 64 6e-10
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 64 6e-10
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 64 8e-10
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 63 1e-09
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 63 1e-09
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 63 1e-09
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 63 1e-09
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 63 1e-09
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 63 1e-09
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 63 1e-09
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 63 1e-09
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 63 1e-09
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 63 1e-09
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 63 1e-09
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 62 3e-09
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 62 3e-09
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 62 3e-09
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 62 3e-09
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 62 3e-09
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 62 3e-09
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 62 3e-09
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 62 3e-09
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 62 3e-09
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 62 3e-09
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 62 3e-09
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 62 3e-09
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 62 3e-09
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 60 1e-08
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 60 1e-08
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 59 2e-08
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 59 2e-08
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 59 2e-08
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 59 2e-08
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 59 2e-08
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 59 2e-08
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 59 2e-08
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 59 2e-08
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 58 3e-08
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 58 3e-08
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 58 3e-08
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 58 4e-08
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 58 4e-08
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 58 4e-08
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 58 5e-08
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 58 5e-08
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 58 5e-08
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 58 5e-08
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 58 5e-08
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 58 5e-08
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 58 5e-08
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 58 5e-08
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 57 7e-08
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 57 7e-08
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 57 7e-08
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 57 7e-08
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 57 7e-08
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 57 7e-08
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 56 1e-07
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 56 1e-07
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 55 3e-07
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 55 3e-07
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 54 7e-07
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 54 7e-07
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 54 7e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 54 7e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 54 7e-07
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 54 7e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 54 7e-07
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 54 7e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 54 7e-07
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 54 7e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 53 1e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 53 1e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 53 2e-06
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 52 2e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 52 2e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 52 2e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 52 2e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 52 2e-06
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 52 3e-06
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 52 3e-06
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 52 3e-06
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 52 3e-06
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 52 4e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 52 4e-06
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 52 4e-06
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 52 4e-06
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 52 4e-06
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 52 4e-06
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 52 4e-06
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 52 4e-06
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 52 4e-06
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 51 5e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 51 5e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 50 1e-05
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 49 2e-05
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 48 3e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 48 3e-05
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 48 4e-05
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 47 8e-05
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 47 8e-05
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 47 8e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 46 2e-04
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 46 2e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 46 2e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 2e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 2e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 46 2e-04
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 45 3e-04
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 45 3e-04
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 45 3e-04
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 45 3e-04
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 45 4e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 45 4e-04
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 45 4e-04
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 45 4e-04
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 45 4e-04
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 45 4e-04
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 45 4e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 45 4e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 45 4e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 45 4e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 44 5e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 44 5e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 44 5e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 44 5e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 43 0.001
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 43 0.001
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 43 0.001
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 40 0.011
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 40 0.011
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 40 0.011
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 39 0.026
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 39 0.026
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 39 0.026
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 38 0.061
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 38 0.061
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 38 0.061
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 34 0.57
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 33 1.00
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 69.7 bits (163), Expect = 1e-11
Identities = 51/189 (26%), Positives = 84/189 (44%), Gaps = 11/189 (5%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 253
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 430
+ L+ W D RL WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 431 VSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM-- 604
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDD 193
Query: 605 -FXSRAWDV 628
S WD+
Sbjct: 194 FTPSGEWDI 202
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 12/190 (6%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 253
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 427
+ L+ W D RL WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM- 604
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 --FXSRAWDV 628
S WD+
Sbjct: 194 DFTPSGEWDI 203
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 12/190 (6%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 253
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 427
+ L+ W D RL WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM- 604
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 --FXSRAWDV 628
S WD+
Sbjct: 194 DFTPSGEWDI 203
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 12/190 (6%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 253
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 427
+ L+ W D RL WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM- 604
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 --FXSRAWDV 628
S WD+
Sbjct: 194 DFTPSGEWDI 203
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 12/190 (6%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 253
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 427
+ L+ W D RL WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM- 604
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 --FXSRAWDV 628
S WD+
Sbjct: 194 DFTPSGEWDI 203
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 12/190 (6%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 253
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 427
+ L+ W D RL WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM- 604
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 --FXSRAWDV 628
S WD+
Sbjct: 194 DFTPSGEWDI 203
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 12/190 (6%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 253
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 427
+ L+ W D RL WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 428 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSM- 604
V +NGSV + + +++ +P D Q CT KF S ++ E+D V+ SM
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 605 --FXSRAWDV 628
S WD+
Sbjct: 194 DFTPSGEWDI 203
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 64.1 bits (149), Expect = 6e-10
Identities = 41/173 (23%), Positives = 80/173 (46%), Gaps = 11/173 (6%)
Frame = +2
Query: 143 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLX 307
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 308 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 484
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 485 ISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFXSRAWDV 628
++ + +P D+Q C+ KFGS ++ ++D + +DKR F + W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 64.1 bits (149), Expect = 6e-10
Identities = 41/173 (23%), Positives = 80/173 (46%), Gaps = 11/173 (6%)
Frame = +2
Query: 143 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLX 307
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 308 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 484
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 485 ISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFXSRAWDV 628
++ + +P D+Q C+ KFGS ++ ++D + +DKR F + W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 64.1 bits (149), Expect = 6e-10
Identities = 41/173 (23%), Positives = 80/173 (46%), Gaps = 11/173 (6%)
Frame = +2
Query: 143 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLX 307
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 308 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 484
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 485 ISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFXSRAWDV 628
++ + +P D+Q C+ KFGS ++ ++D + +DKR F + W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 64.1 bits (149), Expect = 6e-10
Identities = 41/173 (23%), Positives = 80/173 (46%), Gaps = 11/173 (6%)
Frame = +2
Query: 143 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLX 307
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 308 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 484
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 485 ISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFXSRAWDV 628
++ + +P D+Q C+ KFGS ++ ++D + +DKR F + W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 63.7 bits (148), Expect = 8e-10
Identities = 43/150 (28%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRP 370
I + L L L ++ E + + L+ W D RL WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 371 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 547
D+VL N A T V +NGSV + + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 548 RMHNSDEMDFVIDKRIYSM---FXSRAWDV 628
++ E+D V+ SM S WD+
Sbjct: 127 WTYDHTEIDMVLMTPTASMDDFTPSGEWDI 156
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 150
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 63.3 bits (147), Expect = 1e-09
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V + +M + +P D Q C+ KFGS ++ +D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 13/188 (6%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 280
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 281 MNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 445
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFXSR 616
++ + M + +P D Q C+ KFGS ++ E+D +I ++ + +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 617 AWDVTDXS 640
W++ D S
Sbjct: 205 EWEIIDAS 212
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 13/188 (6%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 280
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 281 MNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 445
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFXSR 616
++ + M + +P D Q C+ KFGS ++ E+D +I ++ + +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 617 AWDVTDXS 640
W++ D S
Sbjct: 205 EWEIIDAS 212
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 62.9 bits (146), Expect = 1e-09
Identities = 41/173 (23%), Positives = 79/173 (45%), Gaps = 11/173 (6%)
Frame = +2
Query: 143 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLX 307
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 308 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 484
WN ++G V S+ W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 485 ISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-----IDKRIYSMFXSRAWDV 628
++ + +P D+Q C+ KFGS ++ ++D + +DKR F + W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKR--DFFDNGEWEI 220
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 13/188 (6%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 280
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 281 MNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 445
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFXSR 616
++ + M + +P D Q C+ KFGS ++ E+D +I ++ + +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 617 AWDVTDXS 640
W++ D S
Sbjct: 205 EWEIIDAS 212
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 13/188 (6%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 280
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 281 MNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 445
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD-FVIDKRI--YSMFXSR 616
++ + M + +P D Q C+ KFGS ++ E+D +I ++ + +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 617 AWDVTDXS 640
W++ D S
Sbjct: 205 EWEIIDAS 212
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 160
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 2/105 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 185
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 60.1 bits (139), Expect = 1e-08
Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
V + + S+ + +P D Q C KFGS ++ ++D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 60.1 bits (139), Expect = 1e-08
Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 448
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
V + + S+ + +P D Q C KFGS ++ ++D
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKID 212
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 143 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 307
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFXSRAWDVTD 634
+ S+ + +P D Q CT KFGS ++ ++D V + R+ + S W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 143 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 307
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFXSRAWDVTD 634
+ S+ + +P D Q CT KFGS ++ ++D V + R+ + S W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 143 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 307
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 473 ISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFXSRAWDVTD 634
+ S+ + +P D Q CT KFGS ++ ++D V + R+ + S W + D
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 188
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 143 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 307
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFXSRAWDVTD 634
+ S+ + +P D Q CT KFGS ++ ++D V + R+ + S W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/108 (29%), Positives = 58/108 (53%), Gaps = 5/108 (4%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 439
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 440 NGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVI 583
G V+ I + + + +P D Q CT KFGS ++ ++D V+
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 188
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 143 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 307
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFXSRAWDVTD 634
+ S+ + +P D Q CT KFGS ++ ++D V + R+ + S W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 143 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 307
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFXSRAWDVTD 634
+ S+ + +P D Q CT KFGS ++ ++D V + R+ + S W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 143 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLX 307
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 308 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 472
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 473 ISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV-IDKRI--YSMFXSRAWDVTD 634
+ S+ + +P D Q CT KFGS ++ ++D V + R+ + S W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Frame = +2
Query: 173 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLV 346
RE ++ V L L L N ++ E + ++ DL+ W D RL W+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 347 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSXIKRLDISTPISMQLDXWPNDM 520
++E +W PDVVLLN D AL VS++GSV + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 521 QTCTFKFGSRMHNSDEM 571
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 58.4 bits (135), Expect = 3e-08
Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 451
+ + W + + WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 452 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAWDVT 631
K + +++ ++ + +P D Q CTF F S ++ D M +DK + W++T
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV--------WEIT 202
Query: 632 DXS 640
D S
Sbjct: 203 DTS 205
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Frame = +2
Query: 173 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLV 346
RE ++ V L L L N ++ E + ++ DL+ W D RL W+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 347 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSXIKRLDISTPISMQLDXWPNDM 520
++E +W PDVVLLN D AL VS++GSV + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 521 QTCTFKFGSRMHNSDEM 571
Q CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 58.0 bits (134), Expect = 4e-08
Identities = 35/134 (26%), Positives = 69/134 (51%), Gaps = 3/134 (2%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWG-CSTWLVSSER 358
P+ + ++L + L + ++ E E T+ + ++W D RL ++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 359 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTF 535
+W P++VL N G Y V GSV+ + + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 536 KFGSRMHNSDEMDF 577
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 58.0 bits (134), Expect = 4e-08
Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 451
+ + W + + WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 452 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAWDVT 631
K + +++ + + +P D Q CTF F S ++ D M +DK + W++T
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV--------WEIT 202
Query: 632 DXS 640
D S
Sbjct: 203 DTS 205
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 58.0 bits (134), Expect = 4e-08
Identities = 35/134 (26%), Positives = 69/134 (51%), Gaps = 3/134 (2%)
Frame = +2
Query: 185 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWG-CSTWLVSSER 358
P+ + ++L + L + ++ E E T+ + ++W D RL ++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 359 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTF 535
+W P++VL N G Y V GSV+ + + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 536 KFGSRMHNSDEMDF 577
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 41/150 (27%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 547
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 548 RMHNSDEMDFVIDKRIYSM---FXSRAWDV 628
++ E+D V+ + S+ S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 41/150 (27%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 547
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 548 RMHNSDEMDFVIDKRIYSM---FXSRAWDV 628
++ E+D V+ + S+ S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 41/150 (27%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 547
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 548 RMHNSDEMDFVIDKRIYSM---FXSRAWDV 628
++ E+D V+ + S+ S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 41/150 (27%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 547
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 548 RMHNSDEMDFVIDKRIYSM---FXSRAWDV 628
++ E+D V+ + S+ S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 41/150 (27%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 547
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 548 RMHNSDEMDFVIDKRIYSM---FXSRAWDV 628
++ E+D V+ + S+ S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 41/150 (27%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 547
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 548 RMHNSDEMDFVIDKRIYSM---FXSRAWDV 628
++ E+D V+ + S+ S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 57.6 bits (133), Expect = 5e-08
Identities = 41/150 (27%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 547
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 548 RMHNSDEMDFVIDKRIYSM---FXSRAWDV 628
++ E+D V+ + S+ S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 41/150 (27%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Frame = +2
Query: 197 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRP 370
+ V L + L ++ E E + L W D RL W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 371 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 547
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 548 RMHNSDEMDFVIDKRIYSM---FXSRAWDV 628
++ E+D V+ + S+ S WD+
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDI 205
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 57.2 bits (132), Expect = 7e-08
Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 451
L+M W + + WN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 452 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAWDVT 631
K + + + ++ + +P D Q CT F S ++ D M ++K + W++T
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WEIT 202
Query: 632 DXS 640
D S
Sbjct: 203 DAS 205
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 57.2 bits (132), Expect = 7e-08
Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 451
L+M W + + WN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 452 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAWDVT 631
K + + + ++ + +P D Q CT F S ++ D M ++K + W++T
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WEIT 131
Query: 632 DXS 640
D S
Sbjct: 132 DAS 134
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 57.2 bits (132), Expect = 7e-08
Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 451
L+M W + + WN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 452 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAWDVT 631
K + + + ++ + +P D Q CT F S ++ D M ++K + W++T
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WEIT 217
Query: 632 DXS 640
D S
Sbjct: 218 DAS 220
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 57.2 bits (132), Expect = 7e-08
Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 451
L+M W + + WN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 452 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAWDVT 631
K + + + ++ + +P D Q CT F S ++ D M ++K + W++T
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WEIT 217
Query: 632 DXS 640
D S
Sbjct: 218 DAS 220
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 57.2 bits (132), Expect = 7e-08
Identities = 43/139 (30%), Positives = 69/139 (49%), Gaps = 6/139 (4%)
Frame = +2
Query: 173 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLXWNAGEW-GCSTWLV 346
RE ++ V L L L N ++ E + ++ DL+ W D RL W+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 347 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSXIKRLDISTPISMQLDXWPN 514
++E +W PDVVLLN G++ + VS++GSV + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 515 DMQTCTFKFGSRMHNSDEM 571
D Q CT F S ++S E+
Sbjct: 161 DWQNCTMVFSSYSYDSSEV 179
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 57.2 bits (132), Expect = 7e-08
Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 451
L+M W + + WN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 452 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAWDVT 631
K + + + ++ + +P D Q CT F S ++ D M ++K + W++T
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WEIT 217
Query: 632 DXS 640
D S
Sbjct: 218 DAS 220
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 56.4 bits (130), Expect = 1e-07
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 8/157 (5%)
Frame = +2
Query: 143 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLX 307
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 308 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSXIKRLDIS 478
W+ ++ G V S +WRPD+VL N + AL V S +G + +
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 479 TPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDK 589
+ S+ + +P D Q C+ F S+ ++++E+D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 56.4 bits (130), Expect = 1e-07
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 8/157 (5%)
Frame = +2
Query: 143 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLX 307
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 308 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSXIKRLDIS 478
W+ ++ G V S +WRPD+VL N + AL V S +G + +
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 479 TPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDK 589
+ S+ + +P D Q C+ F S+ ++++E+D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 269 ADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 445
A L + W + + WN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAWD 625
+ K + + + ++ + +P D Q CT F S ++ D M ++K + W+
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WE 200
Query: 626 VTDXS 640
+TD S
Sbjct: 201 ITDAS 205
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 269 ADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 445
A L + W + + WN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAWD 625
+ K + + + ++ + +P D Q CT F S ++ D M ++K + W+
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WE 185
Query: 626 VTDXS 640
+TD S
Sbjct: 186 ITDAS 190
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 54.0 bits (124), Expect = 7e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 275 -LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 445
++ W D L W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 54.0 bits (124), Expect = 7e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 275 -LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 445
++ W D L W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 54.0 bits (124), Expect = 7e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 275 -LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 445
++ W D L W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 54.0 bits (124), Expect = 7e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 110 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 274
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 275 ---LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 439
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 440 NGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
+G+V + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 54.0 bits (124), Expect = 7e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 110 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 274
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 275 ---LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 439
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 440 NGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
+G+V + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 54.0 bits (124), Expect = 7e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 275 -LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 445
++ W D L W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 54.0 bits (124), Expect = 7e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 110 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 274
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 275 ---LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 439
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 440 NGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
+G+V + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 54.0 bits (124), Expect = 7e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 275 -LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 445
++ W D L W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
++ + + + +P D Q C FGS +N +++D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 54.0 bits (124), Expect = 7e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 110 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 274
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 275 ---LQMNWIDKRLXWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 439
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 440 NGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
+G+V + + + +P D Q C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 54.0 bits (124), Expect = 7e-07
Identities = 38/163 (23%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +2
Query: 107 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 274
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 275 -LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 445
++ W D L W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 141
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
++ + + + +P D Q C FGS +N +++D
Sbjct: 142 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 454
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 455 XIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
L T + +L +P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 454
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 455 XIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
L T + +L +P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 52.8 bits (121), Expect = 2e-06
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 454
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 455 XIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
L T + +L +P D C+ F + + + E++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 448
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFXSRAWD 625
+ + + + +P D+Q C KFGS + +D + + I + WD
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 174
Query: 626 V 628
+
Sbjct: 175 L 175
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 448
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFXSRAWD 625
+ + + + +P D+Q C KFGS + +D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 626 V 628
+
Sbjct: 198 L 198
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 448
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFXSRAWD 625
+ + + + +P D+Q C KFGS + +D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 626 V 628
+
Sbjct: 198 L 198
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 448
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFXSRAWD 625
+ + + + +P D+Q C KFGS + +D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 626 V 628
+
Sbjct: 198 L 198
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 448
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFXSRAWD 625
+ + + + +P D+Q C KFGS + +D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 626 V 628
+
Sbjct: 198 L 198
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 52.0 bits (119), Expect = 3e-06
Identities = 39/161 (24%), Positives = 71/161 (44%), Gaps = 7/161 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 286
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 287 WIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 457
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 458 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV 580
RL IS MQL+ +P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 52.0 bits (119), Expect = 3e-06
Identities = 39/161 (24%), Positives = 71/161 (44%), Gaps = 7/161 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 286
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 287 WIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 457
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 458 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV 580
RL IS MQL+ +P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 52.0 bits (119), Expect = 3e-06
Identities = 39/161 (24%), Positives = 71/161 (44%), Gaps = 7/161 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 286
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 287 WIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 457
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 458 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV 580
RL IS MQL+ +P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 52.0 bits (119), Expect = 3e-06
Identities = 39/161 (24%), Positives = 71/161 (44%), Gaps = 7/161 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 286
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 287 WIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 457
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 458 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFV 580
RL IS MQL+ +P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 51.6 bits (118), Expect = 4e-06
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Frame = +2
Query: 194 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRP 370
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 371 DVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFK 538
D+VL N A GD+A+ + + G ++ + + + +P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 539 FGS 547
G+
Sbjct: 166 LGT 168
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 167 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWG- 328
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 329 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDX 505
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 506 WPNDMQTCTFKFGSRMHNSDEM 571
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 51.6 bits (118), Expect = 4e-06
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Frame = +2
Query: 194 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRP 370
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 371 DVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFK 538
D+VL N A GD+A+ + + G ++ + + + +P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 539 FGS 547
G+
Sbjct: 166 LGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 51.6 bits (118), Expect = 4e-06
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Frame = +2
Query: 194 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRP 370
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 371 DVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFK 538
D+VL N A GD+A+ + + G ++ + + + +P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 539 FGS 547
G+
Sbjct: 166 LGT 168
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 167 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWG- 328
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 329 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDX 505
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 506 WPNDMQTCTFKFGSRMHNSDEM 571
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 167 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWG- 328
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 329 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDX 505
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 506 WPNDMQTCTFKFGSRMHNSDEM 571
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 51.6 bits (118), Expect = 4e-06
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Frame = +2
Query: 194 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRP 370
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 371 DVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFK 538
D+VL N A GD+A+ + + G ++ + + + +P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 539 FGS 547
G+
Sbjct: 166 LGT 168
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 167 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLXWNAGEWG- 328
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 329 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDX 505
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 506 WPNDMQTCTFKFGSRMHNSDEM 571
+P D Q C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 51.6 bits (118), Expect = 4e-06
Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Frame = +2
Query: 194 KIVVNLTLHLRHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRP 370
++ V L L ++ N+ E V L+ W+D L WN ++G + + SE++WRP
Sbjct: 50 EVTVGLQL-IQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRP 108
Query: 371 DVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFK 538
D+VL N A GD+A+ + + G ++ + + + +P D Q C+ K
Sbjct: 109 DLVLYNNA---DGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMK 165
Query: 539 FGS 547
G+
Sbjct: 166 LGT 168
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 51.2 bits (117), Expect = 5e-06
Identities = 31/121 (25%), Positives = 54/121 (44%), Gaps = 3/121 (2%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 448
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFXSRAWD 625
+ + + + +P D+Q C KFGS + +D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 626 V 628
+
Sbjct: 198 L 198
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 51.2 bits (117), Expect = 5e-06
Identities = 31/121 (25%), Positives = 54/121 (44%), Gaps = 3/121 (2%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 448
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 449 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKR-IYSMFXSRAWD 625
+ + + + +P D+Q C KFGS + +D + + I + WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 626 V 628
+
Sbjct: 198 L 198
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/89 (29%), Positives = 40/89 (44%)
Frame = +2
Query: 275 LQMNWIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 454
L+++W+D RL WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 455 XIKRLDISTPISMQLDXWPNDMQTCTFKF 541
L T + +L +P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 48.8 bits (111), Expect = 2e-05
Identities = 36/158 (22%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 286
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 287 WIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 457
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 458 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEM 571
RL I M L+ +P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 48.4 bits (110), Expect = 3e-05
Identities = 36/158 (22%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 286
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 287 WIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 457
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 458 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEM 571
RL I M L+ +P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 48.4 bits (110), Expect = 3e-05
Identities = 36/158 (22%), Positives = 68/158 (43%), Gaps = 7/158 (4%)
Frame = +2
Query: 119 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 286
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 287 WIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 457
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 458 IKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEM 571
RL I M L+ +P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 1/111 (0%)
Frame = +2
Query: 233 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 409
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 410 DYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNS 562
+ + G V K L + T S+ + +P D+Q C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 47.2 bits (107), Expect = 8e-05
Identities = 38/172 (22%), Positives = 71/172 (41%), Gaps = 7/172 (4%)
Frame = +2
Query: 128 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 295
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 296 KRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 466
RL +N+ + +W PD + N+ A R+ N+G + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 467 LDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAW 622
L I+ +QL +P D +C F S + +EM + K ++W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 47.2 bits (107), Expect = 8e-05
Identities = 38/172 (22%), Positives = 71/172 (41%), Gaps = 7/172 (4%)
Frame = +2
Query: 128 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 295
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 296 KRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 466
RL +N+ + +W PD + N+ A R+ N+G + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 467 LDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAW 622
L I+ +QL +P D +C F S + +EM + K ++W
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 216
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 47.2 bits (107), Expect = 8e-05
Identities = 38/172 (22%), Positives = 71/172 (41%), Gaps = 7/172 (4%)
Frame = +2
Query: 128 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 295
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 296 KRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKR 466
RL +N+ + +W PD + N+ A R+ N+G + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 467 LDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDKRIYSMFXSRAW 622
L I+ +QL +P D +C F S + +EM + K ++W
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSW 198
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 46.0 bits (104), Expect = 2e-04
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Frame = +2
Query: 242 ESESTVRILADLQMNWIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 421
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 422 RA---RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDK 589
R+ NG++ RL IS M+L +P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 46.0 bits (104), Expect = 2e-04
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Frame = +2
Query: 242 ESESTVRILADLQMNWIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 421
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 422 RA---RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDK 589
R+ NG++ RL IS M+L +P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLXWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLXWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLXWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 253
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 415
+ L+ W D RL WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 95 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 253
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 254 TVRILADLQMNWIDKRLXWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 415
+ L+ W D RL WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLXWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLXWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 113 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 277
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 278 QMNWIDKRLXWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 445
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 446 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
+V R+ + +M L +P D QTC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 45.2 bits (102), Expect = 3e-04
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
Frame = +2
Query: 143 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLX 307
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 29 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 88
Query: 308 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT 400
W+ ++ G V S +WRPD+VL N + T
Sbjct: 89 WDPRDYEGLWVLRVPSTMVWRPDIVLENKSQT 120
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 44.8 bits (101), Expect = 4e-04
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 44.8 bits (101), Expect = 4e-04
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 44.8 bits (101), Expect = 4e-04
Identities = 38/166 (22%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Frame = +2
Query: 131 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 298
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 299 RLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 469
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 470 DISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 604
I+ M+L +P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.8 bits (101), Expect = 4e-04
Identities = 38/166 (22%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Frame = +2
Query: 131 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 298
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 299 RLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 469
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 470 DISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 604
I+ M+L +P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.8 bits (101), Expect = 4e-04
Identities = 38/166 (22%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Frame = +2
Query: 131 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 298
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 299 RLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 469
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 470 DISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 604
I+ M+L +P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.8 bits (101), Expect = 4e-04
Identities = 38/166 (22%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Frame = +2
Query: 131 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 298
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 299 RLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 469
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 470 DISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 604
I+ M+L +P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.8 bits (101), Expect = 4e-04
Identities = 38/166 (22%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Frame = +2
Query: 131 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 298
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 299 RLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 469
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 470 DISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDFVIDK-RIYSM 604
I+ M+L +P D C KFGS + E+ + K +YS+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSV 196
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 44.8 bits (101), Expect = 4e-04
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 44.8 bits (101), Expect = 4e-04
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 44.8 bits (101), Expect = 4e-04
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL ++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 44.4 bits (100), Expect = 5e-04
Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 283
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 284 NWIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 454
W D RL + + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 455 XIKRLDISTPISMQLDXWPNDMQTC 529
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 44.4 bits (100), Expect = 5e-04
Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 283
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 284 NWIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 454
W D RL + + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 455 XIKRLDISTPISMQLDXWPNDMQTC 529
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 44.4 bits (100), Expect = 5e-04
Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 283
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 284 NWIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 454
W D RL + + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 455 XIKRLDISTPISMQLDXWPNDMQTC 529
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 44.4 bits (100), Expect = 5e-04
Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 116 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 283
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 284 NWIDKRLXWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 454
W D RL + + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 455 XIKRLDISTPISMQLDXWPNDMQTC 529
RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/149 (24%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Frame = +2
Query: 146 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLXWN 313
+D L+A Y R P VN+ L L A+I E+ + L +W D RL +N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 314 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 484
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 485 ISMQLDXWPNDMQTCTFKFGSRMHNSDEM 571
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/149 (24%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Frame = +2
Query: 146 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLXWN 313
+D L+A Y R P VN+ L L A+I E+ + L +W D RL +N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 314 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 484
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 485 ISMQLDXWPNDMQTCTFKFGSRMHNSDEM 571
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/149 (24%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Frame = +2
Query: 146 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLXWN 313
+D L+A Y R P VN+ L L A+I E+ + L +W D RL +N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 314 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 484
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 485 ISMQLDXWPNDMQTCTFKFGSRMHNSDEM 571
M L +P D Q C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 39.9 bits (89), Expect = 0.011
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
Frame = +2
Query: 233 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 409
+I E+ R+ L+ W D RL +N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 410 DYALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
+ R+S NG+V R+ ++ M L +P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 39.9 bits (89), Expect = 0.011
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
Frame = +2
Query: 233 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 409
+I E+ R+ L+ W D RL +N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 410 DYALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
+ R+S NG+V R+ ++ M L +P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 39.9 bits (89), Expect = 0.011
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
Frame = +2
Query: 233 NIRESESTVRILADLQMNWIDKRLXWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 409
+I E+ R+ L+ W D RL +N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 410 DYALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
+ R+S NG+V R+ ++ M L +P D+QTC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 38.7 bits (86), Expect = 0.026
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 38.7 bits (86), Expect = 0.026
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 38.7 bits (86), Expect = 0.026
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ +I E+ R+ L+ W D RL ++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 37.5 bits (83), Expect = 0.061
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ ++I ++ R+ L+ W D RL +
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N + R+ NG+V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 37.5 bits (83), Expect = 0.061
Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 4/110 (3%)
Frame = +2
Query: 260 RILADLQMNWIDKRLXWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 427
R+ L+ W D RL +N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 428 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMDF 577
R+S NG+V R+ ++ M L +P D+QTC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 37.5 bits (83), Expect = 0.061
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 8/145 (5%)
Frame = +2
Query: 167 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLXWNAGEWGCS 334
YD P+ K VN+T ++ ++I ++ R+ L+ W D RL +
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 335 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 502
S + +W+PD+ N + R+ NG+V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 503 XWPNDMQTCTFKFGSRMHNSDEMDF 577
+P D+QTCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 34.3 bits (75), Expect = 0.57
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
Frame = +2
Query: 359 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFK 538
LW +A A + +A + ++G V + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 539 FGSRMHNSDEMDFV-IDKRI--YSMFXSRAWDVTD 634
FGS ++ ++D V + R+ + S W + D
Sbjct: 85 FGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 119
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 33.5 bits (73), Expect = 1.00
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 7/83 (8%)
Frame = +2
Query: 407 GDYAL----RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMHNSDEMD 574
GD+A+ +A + ++G V + S+ + +P D Q CT KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 575 FV-IDKRI--YSMFXSRAWDVTD 634
V + R+ + S W + D
Sbjct: 120 LVNMHSRVDQLDFWESGEWVIVD 142
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,273,637
Number of Sequences: 237096
Number of extensions: 2163608
Number of successful extensions: 5167
Number of sequences better than 10.0: 154
Number of HSP's better than 10.0 without gapping: 4814
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5031
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10816958492
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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