Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP17_FL5_A02
(911 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 70 1e-11
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 68 5e-11
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 68 5e-11
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 68 5e-11
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 68 5e-11
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 68 5e-11
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 68 5e-11
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 65 3e-10
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 65 3e-10
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 65 3e-10
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 65 3e-10
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 65 3e-10
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 65 3e-10
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 65 3e-10
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 64 7e-10
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 64 7e-10
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 64 7e-10
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 64 7e-10
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 64 9e-10
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 63 2e-09
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 62 2e-09
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 62 2e-09
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 62 2e-09
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 62 2e-09
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 62 2e-09
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 62 2e-09
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 62 2e-09
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 62 2e-09
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 62 2e-09
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 62 2e-09
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 62 2e-09
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 62 2e-09
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 62 2e-09
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 62 2e-09
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 62 2e-09
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 62 2e-09
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 62 2e-09
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 62 2e-09
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 62 2e-09
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 60 8e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 60 8e-09
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 60 1e-08
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 60 1e-08
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 60 1e-08
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 60 1e-08
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 60 1e-08
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 60 1e-08
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 59 2e-08
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 59 2e-08
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 59 2e-08
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 59 2e-08
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 59 2e-08
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 59 2e-08
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 59 2e-08
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 59 2e-08
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 59 3e-08
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 59 3e-08
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 58 4e-08
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 58 4e-08
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 58 6e-08
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 58 6e-08
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 58 6e-08
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 58 6e-08
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 58 6e-08
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 58 6e-08
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 57 8e-08
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 57 8e-08
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 56 1e-07
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 56 1e-07
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 56 1e-07
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 56 1e-07
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 56 1e-07
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 56 1e-07
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 56 1e-07
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 56 2e-07
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 56 2e-07
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 55 3e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 55 3e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 55 3e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 55 3e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 55 3e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 55 3e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 55 3e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 55 3e-07
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 55 4e-07
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 55 4e-07
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 55 4e-07
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 55 4e-07
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 55 4e-07
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 55 4e-07
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 53 1e-06
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 53 1e-06
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 53 1e-06
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 53 1e-06
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 53 1e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 53 2e-06
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 52 3e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 52 3e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 52 3e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 52 3e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 52 3e-06
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 52 3e-06
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 52 4e-06
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 52 4e-06
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 52 4e-06
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 52 4e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 51 7e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 51 7e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 51 7e-06
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 50 9e-06
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 50 9e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 50 9e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 50 9e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 50 9e-06
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 50 1e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 50 1e-05
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 50 2e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 49 2e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 49 2e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 49 2e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 49 3e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 49 3e-05
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 49 3e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 49 3e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 49 3e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 49 3e-05
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 48 4e-05
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 48 4e-05
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 48 4e-05
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 48 4e-05
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 48 4e-05
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 48 4e-05
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 48 4e-05
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 48 4e-05
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 48 4e-05
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 48 5e-05
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 48 5e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 48 5e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 48 5e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 48 5e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 48 5e-05
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 48 5e-05
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 48 5e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 48 6e-05
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 48 6e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 46 1e-04
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 46 1e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 46 2e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 46 2e-04
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 45 3e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 45 4e-04
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 45 4e-04
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 45 4e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 44 6e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 44 6e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 44 6e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 44 6e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 44 6e-04
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 44 0.001
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 44 0.001
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 43 0.002
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.002
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.002
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 43 0.002
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 43 0.002
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.002
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 43 0.002
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 42 0.002
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 42 0.003
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 42 0.004
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 34 0.62
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 33 1.1
U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated prot... 31 5.8
CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein. 31 5.8
BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1, ... 31 5.8
AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens ... 31 5.8
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 7.7
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 7.7
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 7.7
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 7.7
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 7.7
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 69.7 bits (163), Expect = 1e-11
Identities = 45/171 (26%), Positives = 78/171 (45%), Gaps = 8/171 (4%)
Frame = +2
Query: 59 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 217
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 218 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 395 VSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V +NGSV W+ + +++ +P D Q CT KF S + +D +
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 184
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 59 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 217
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 218 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 391
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 392 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V +NGSV W+ + +++ +P D Q CT KF S + +D +
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 59 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 217
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 218 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 391
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 392 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V +NGSV W+ + +++ +P D Q CT KF S + +D +
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 59 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 217
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 218 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 391
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 392 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V +NGSV W+ + +++ +P D Q CT KF S + +D +
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 59 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 217
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 218 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 391
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 392 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V +NGSV W+ + +++ +P D Q CT KF S + +D +
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 59 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 217
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 218 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 391
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 392 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V +NGSV W+ + +++ +P D Q CT KF S + +D +
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 67.7 bits (158), Expect = 5e-11
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Frame = +2
Query: 59 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 217
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 218 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 391
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 392 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V +NGSV W+ + +++ +P D Q CT KF S + +D +
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 370
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 371 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
G + V +NG+V W + +M + +P D Q C+ KFGS + +D +
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 65.3 bits (152), Expect = 3e-10
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 370
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 371 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
G + V +NG+V W + +M + +P D Q C+ KFGS + +D +
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 150
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 370
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 371 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
G + V +NG+V W + +M + +P D Q C+ KFGS + +D +
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 370
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 371 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
G + V +NG+V W + +M + +P D Q C+ KFGS + +D +
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 370
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 371 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
G + V +NG+V W + +M + +P D Q C+ KFGS + +D +
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 370
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 371 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
G + V +NG+V W + +M + +P D Q C+ KFGS + +D +
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 65.3 bits (152), Expect = 3e-10
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTA 370
++ E + L+ W D +L WN ++G + V SE LW PD+VL NA
Sbjct: 67 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 126
Query: 371 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
G + V +NG+V W + +M + +P D Q C+ KFGS + +D +
Sbjct: 127 GSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 64.1 bits (149), Expect = 7e-10
Identities = 37/154 (24%), Positives = 71/154 (46%), Gaps = 6/154 (3%)
Frame = +2
Query: 107 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 271
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 272 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 448
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 449 ISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXID 550
++ + +P D+Q C+ KFGS + +D ++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 64.1 bits (149), Expect = 7e-10
Identities = 37/154 (24%), Positives = 71/154 (46%), Gaps = 6/154 (3%)
Frame = +2
Query: 107 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 271
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 272 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 448
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 449 ISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXID 550
++ + +P D+Q C+ KFGS + +D ++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 64.1 bits (149), Expect = 7e-10
Identities = 37/154 (24%), Positives = 71/154 (46%), Gaps = 6/154 (3%)
Frame = +2
Query: 107 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 271
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 272 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 448
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 449 ISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXID 550
++ + +P D+Q C+ KFGS + +D ++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 64.1 bits (149), Expect = 7e-10
Identities = 37/154 (24%), Positives = 71/154 (46%), Gaps = 6/154 (3%)
Frame = +2
Query: 107 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 271
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 272 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 448
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 449 ISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXID 550
++ + +P D+Q C+ KFGS + +D ++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 63.7 bits (148), Expect = 9e-10
Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 3/132 (2%)
Frame = +2
Query: 161 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 334
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 335 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
D+VL N A T V +NGSV W+ + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 512 RMHXXDXMDFXI 547
+ +D +
Sbjct: 127 WTYDHTEIDMVL 138
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 62.9 bits (146), Expect = 2e-09
Identities = 37/154 (24%), Positives = 70/154 (45%), Gaps = 6/154 (3%)
Frame = +2
Query: 107 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 271
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 272 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 448
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 449 ISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXID 550
++ + +P D+Q C+ KFGS + +D ++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILE 203
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/166 (25%), Positives = 75/166 (45%), Gaps = 10/166 (6%)
Frame = +2
Query: 80 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 244
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 245 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 409
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
++W + M + +P D Q C+ KFGS + +D I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 62.5 bits (145), Expect = 2e-09
Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 370
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 371 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
+ +A + + G+V W+ + S+ + +P D Q C KFGS
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 160
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/166 (25%), Positives = 75/166 (45%), Gaps = 10/166 (6%)
Frame = +2
Query: 80 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 244
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 245 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 409
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
++W + M + +P D Q C+ KFGS + +D I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 62.5 bits (145), Expect = 2e-09
Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTA 370
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A A
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFA 156
Query: 371 GDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
+ +A + + G+V W+ + S+ + +P D Q C KFGS
Sbjct: 157 VTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/166 (25%), Positives = 75/166 (45%), Gaps = 10/166 (6%)
Frame = +2
Query: 80 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 244
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 245 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 409
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
++W + M + +P D Q C+ KFGS + +D I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 412
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 413 VSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 185
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/166 (25%), Positives = 75/166 (45%), Gaps = 10/166 (6%)
Frame = +2
Query: 80 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 244
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 245 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 409
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
++W + M + +P D Q C+ KFGS + +D I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 60.5 bits (140), Expect = 8e-09
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Frame = +2
Query: 158 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 331
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 332 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 505
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 506 GS 511
S
Sbjct: 170 SS 171
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.5 bits (140), Expect = 8e-09
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Frame = +2
Query: 158 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 331
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 332 PDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKF 505
PDVVLLN D AL VS++GSV W + S+Q+ +P D Q CT F
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTMVF 169
Query: 506 GS 511
S
Sbjct: 170 SS 171
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 60.1 bits (139), Expect = 1e-08
Identities = 43/168 (25%), Positives = 77/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 38 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NI 202
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 203 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 379
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 380 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
A+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 60.1 bits (139), Expect = 1e-08
Identities = 43/168 (25%), Positives = 77/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 38 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NI 202
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 203 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 379
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 380 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
A+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 60.1 bits (139), Expect = 1e-08
Identities = 43/168 (25%), Positives = 77/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 38 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NI 202
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 203 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 379
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 380 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
A+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 60.1 bits (139), Expect = 1e-08
Identities = 32/108 (29%), Positives = 56/108 (51%), Gaps = 5/108 (4%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 403
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 404 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
G V+WI + + + +P D Q CT KFGS + +D +
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 188
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 60.1 bits (139), Expect = 1e-08
Identities = 43/168 (25%), Positives = 77/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 38 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NI 202
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 203 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 379
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 380 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
A+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 60.1 bits (139), Expect = 1e-08
Identities = 43/168 (25%), Positives = 77/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 38 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NI 202
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 203 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 379
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 380 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
A+ + + G ++W + + + ++P D Q C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 107 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 271
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 272 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 436
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 107 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 271
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 272 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 436
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 107 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 271
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 272 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 436
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
+ S+ + +P D Q CT KFGS
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGS 156
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 107 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 271
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 272 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 436
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 107 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 271
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 272 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 436
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 107 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 271
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 272 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 436
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 107 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 271
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 272 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 436
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 59.3 bits (137), Expect = 2e-08
Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 6/124 (4%)
Frame = +2
Query: 158 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 331
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 332 PDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 499
PDVVLLN G++ + VS++GSV W + S+Q+ +P D Q CT
Sbjct: 111 PDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDWQNCTM 167
Query: 500 KFGS 511
F S
Sbjct: 168 VFSS 171
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 58.8 bits (136), Expect = 3e-08
Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 8/157 (5%)
Frame = +2
Query: 107 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 271
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 272 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 442
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 443 TPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDK 553
+ S+ + +P D Q C+ F S+ + + +D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 58.8 bits (136), Expect = 3e-08
Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 8/157 (5%)
Frame = +2
Query: 107 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 271
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 272 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 442
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 443 TPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDK 553
+ S+ + +P D Q C+ F S+ + + +D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 58.0 bits (134), Expect = 4e-08
Identities = 34/134 (25%), Positives = 68/134 (50%), Gaps = 3/134 (2%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 322
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 323 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 499
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 500 KFGSRMHXXDXMDF 541
F S+ + + ++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 58.0 bits (134), Expect = 4e-08
Identities = 34/134 (25%), Positives = 68/134 (50%), Gaps = 3/134 (2%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 322
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 323 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTF 499
+W P++VL N G Y V GSV+W+ + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 500 KFGSRMHXXDXMDF 541
F S+ + + ++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 57.6 bits (133), Expect = 6e-08
Identities = 29/108 (26%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 415
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 416 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDKRM 559
+ K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV 198
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 57.6 bits (133), Expect = 6e-08
Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 1/108 (0%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 415
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 416 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDKRM 559
+ K + +++ ++ + +P D Q CTF F S ++ D M +DK +
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV 198
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 57.6 bits (133), Expect = 6e-08
Identities = 29/108 (26%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 415
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 416 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDKRM 559
+ K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV 127
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 57.6 bits (133), Expect = 6e-08
Identities = 29/108 (26%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 415
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 416 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDKRM 559
+ K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV 213
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 57.6 bits (133), Expect = 6e-08
Identities = 29/108 (26%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 415
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 416 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDKRM 559
+ K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV 213
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 57.6 bits (133), Expect = 6e-08
Identities = 29/108 (26%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 415
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 416 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDKRM 559
+ K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV 213
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 57.2 bits (132), Expect = 8e-08
Identities = 45/174 (25%), Positives = 74/174 (42%), Gaps = 4/174 (2%)
Frame = +2
Query: 38 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIV-VNLTLHLRHA-NIRES 211
+ L C+ A+ E L+ S R + S++V V L + L ++ E
Sbjct: 14 FGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHER 73
Query: 212 ESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 385
E + L W D RL+W E+ + S+ +W PDVVL N A +
Sbjct: 74 EQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYS 133
Query: 386 RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXI 547
A VS +GS+ W+ + +++ ++P D Q CT KF S + +D +
Sbjct: 134 NAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVL 187
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 57.2 bits (132), Expect = 8e-08
Identities = 28/108 (25%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 415
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 416 SWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDKRM 559
+ K + +++ + + +P D Q CTF F S ++ D M +DK +
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV 198
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 161 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 334
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 335 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 512 RMHXXDXMDFXI 547
+ +D +
Sbjct: 176 WTYDRTEIDLVL 187
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 161 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 334
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 335 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 512 RMHXXDXMDFXI 547
+ +D +
Sbjct: 176 WTYDRTEIDLVL 187
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 161 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 334
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 335 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 512 RMHXXDXMDFXI 547
+ +D +
Sbjct: 176 WTYDRTEIDLVL 187
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 161 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 334
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 335 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 512 RMHXXDXMDFXI 547
+ +D +
Sbjct: 176 WTYDRTEIDLVL 187
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 161 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 334
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 335 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 512 RMHXXDXMDFXI 547
+ +D +
Sbjct: 176 WTYDRTEIDLVL 187
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 161 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 334
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 335 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 512 RMHXXDXMDFXI 547
+ +D +
Sbjct: 176 WTYDRTEIDLVL 187
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Frame = +2
Query: 161 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 334
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 335 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
DVVL N A + A VS +GS+ W+ + +++ ++P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 512 RMHXXDXMDFXI 547
+ +D +
Sbjct: 176 WTYDRTEIDLVL 187
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 56.0 bits (129), Expect = 2e-07
Identities = 29/112 (25%), Positives = 55/112 (49%), Gaps = 1/112 (0%)
Frame = +2
Query: 227 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 403
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 404 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDKRM 559
G + + K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 147 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV 198
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 56.0 bits (129), Expect = 2e-07
Identities = 29/112 (25%), Positives = 55/112 (49%), Gaps = 1/112 (0%)
Frame = +2
Query: 227 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN 403
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 404 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDFXIDKRM 559
G + + K + + + ++ + +P D Q CT F S ++ D M ++K +
Sbjct: 132 EGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV 183
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 55.2 bits (127), Expect = 3e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 152 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 325
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 326 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 502
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 503 FGS 511
F S
Sbjct: 169 FSS 171
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 55.2 bits (127), Expect = 3e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 152 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 325
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 326 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 502
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 503 FGS 511
F S
Sbjct: 169 FSS 171
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 55.2 bits (127), Expect = 3e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 152 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 325
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 326 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 502
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 503 FGS 511
F S
Sbjct: 169 FSS 171
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +2
Query: 74 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 229
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 230 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 403
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 404 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMD 538
+G+V W + + + +P D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +2
Query: 74 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 229
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 230 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 403
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 404 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMD 538
+G+V W + + + +P D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +2
Query: 74 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 229
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 230 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 403
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 404 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMD 538
+G+V W + + + +P D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +2
Query: 74 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 229
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 230 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 403
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 404 NGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMD 538
+G+V W + + + +P D Q C FGS H +D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 55.2 bits (127), Expect = 3e-07
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 3/123 (2%)
Frame = +2
Query: 152 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 325
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 326 WRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 502
W P++VL N + Y+ V + G V W+ + + + +P D Q C+ K
Sbjct: 109 WLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLK 168
Query: 503 FGS 511
F S
Sbjct: 169 FSS 171
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 26 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 187
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 188 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 364
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 365 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
++ R+ +G+V + R+ + M L +P D Q CT + S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 536 DF 541
+F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 54.8 bits (126), Expect = 4e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 26 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 187
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 188 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 364
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 365 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
++ R+ +G+V + R+ + M L +P D Q CT + S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 536 DF 541
+F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 26 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 187
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 188 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 364
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 365 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
++ R+ +G+V + R+ + M L +P D Q CT + S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 536 DF 541
+F
Sbjct: 189 EF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 26 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 187
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 188 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 364
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 365 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
++ R+ +G+V + R+ + M L +P D Q CT + S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 536 DF 541
+F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 26 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 187
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 188 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 364
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 365 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
++ R+ +G+V + R+ + M L +P D Q CT + S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 536 DF 541
+F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 54.8 bits (126), Expect = 4e-07
Identities = 44/182 (24%), Positives = 78/182 (42%), Gaps = 10/182 (5%)
Frame = +2
Query: 26 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHL 187
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 188 RHAN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 364
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 365 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
++ R+ +G+V + R+ + M L +P D Q CT + S + D +
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 536 DF 541
+F
Sbjct: 189 EF 190
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/180 (23%), Positives = 79/180 (43%), Gaps = 10/180 (5%)
Frame = +2
Query: 29 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRH 193
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 194 ANIRESESTVRIQAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 361
+ I++ + +I ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 362 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMD 538
+ + + +G ++W + + + +P D Q C FGS + + +D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/180 (23%), Positives = 79/180 (43%), Gaps = 10/180 (5%)
Frame = +2
Query: 29 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRH 193
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 194 ANIRESESTVRIQAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 361
+ I++ + +I ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 362 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMD 538
+ + + +G ++W + + + +P D Q C FGS + + +D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/180 (23%), Positives = 79/180 (43%), Gaps = 10/180 (5%)
Frame = +2
Query: 29 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRH 193
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 194 ANIRESESTVRIQAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 361
+ I++ + +I ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 362 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMD 538
+ + + +G ++W + + + +P D Q C FGS + + +D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/180 (23%), Positives = 79/180 (43%), Gaps = 10/180 (5%)
Frame = +2
Query: 29 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRH 193
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 194 ANIRESESTVRIQAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 361
+ I++ + +I ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 362 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMD 538
+ + + +G ++W + + + +P D Q C FGS + + +D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/180 (23%), Positives = 79/180 (43%), Gaps = 10/180 (5%)
Frame = +2
Query: 29 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRH 193
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 194 ANIRESESTVRIQAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 361
+ I++ + +I ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 362 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMD 538
+ + + +G ++W + + + +P D Q C FGS + + +D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 52.8 bits (121), Expect = 2e-06
Identities = 40/133 (30%), Positives = 63/133 (47%), Gaps = 7/133 (5%)
Frame = +2
Query: 47 LLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RES 211
LL A+ A+ N L+ D L+ YD + P + VVN++L L N+ E
Sbjct: 11 LLLLAVCLGAQGRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNER 68
Query: 212 ESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYAL 385
E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + + L
Sbjct: 69 EEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDL 128
Query: 386 RARVSNNGSVSWI 424
+ + S+ WI
Sbjct: 129 QLSQEDGQSIEWI 141
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 140 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 316
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 81
Query: 317 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 493
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 82 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 141
Query: 494 TFKFGS 511
KFGS
Sbjct: 142 KLKFGS 147
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 140 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 316
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 317 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 493
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 494 TFKFGS 511
KFGS
Sbjct: 165 KLKFGS 170
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 140 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 316
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 317 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 493
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 494 TFKFGS 511
KFGS
Sbjct: 165 KLKFGS 170
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 140 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 316
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 317 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 493
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 494 TFKFGS 511
KFGS
Sbjct: 165 KLKFGS 170
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 52.0 bits (119), Expect = 3e-06
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 2/126 (1%)
Frame = +2
Query: 140 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 316
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 317 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 493
++W+PD++L N+A + V+++G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 494 TFKFGS 511
KFGS
Sbjct: 165 KLKFGS 170
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/163 (22%), Positives = 73/163 (44%), Gaps = 7/163 (4%)
Frame = +2
Query: 71 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 238
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 239 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 409
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMD 538
++W + + + +P D Q C FGS + + +D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 83 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 250
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 251 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 421
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 422 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 83 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 250
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 251 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 421
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 422 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 83 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 250
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 251 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 421
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 422 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 83 ENATSLSLMIDSLLATYDRDSPPD--SKIV-VNLTLHLRHAN-IRESESTVRIQADLQMN 250
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 251 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 421
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 422 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
RL IS MQL+++P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 50.8 bits (116), Expect = 7e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 418
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 419 WIKRLDISTPISMQLDNWPNDMQTCTFKF 505
L T + +L ++P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.8 bits (116), Expect = 7e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 418
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 419 WIKRLDISTPISMQLDNWPNDMQTCTFKF 505
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 50.8 bits (116), Expect = 7e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 418
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 419 WIKRLDISTPISMQLDNWPNDMQTCTFKF 505
L T + +L ++P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 50.4 bits (115), Expect = 9e-06
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = +2
Query: 140 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 316
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 317 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 493
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 494 TFKFGS 511
KFGS
Sbjct: 165 KLKFGS 170
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 50.4 bits (115), Expect = 9e-06
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 7/171 (4%)
Frame = +2
Query: 50 LTCAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESES 217
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 218 TVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 388
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 389 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDF 541
R+ +G+V + R+ + M L +P D Q CT + S + D ++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 50.4 bits (115), Expect = 9e-06
Identities = 35/150 (23%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 83 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 250
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 251 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 421
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 422 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 50.4 bits (115), Expect = 9e-06
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = +2
Query: 140 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 316
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 317 ERLWRPDVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTC 493
++W+PD++L N+A + V+ +G ++ + + + +P D+Q C
Sbjct: 105 GQIWKPDILLYNSADERFDATFHTNVLVNPSGHCQYLPPGIFKSSCYIDVRWFPFDVQHC 164
Query: 494 TFKFGS 511
KFGS
Sbjct: 165 KLKFGS 170
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 50.4 bits (115), Expect = 9e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 239 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 418
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 419 WIKRLDISTPISMQLDNWPNDMQTCTFKF 505
L T + +L ++P D C+ F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSF 174
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 50.0 bits (114), Expect = 1e-05
Identities = 35/150 (23%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 83 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 250
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 251 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 421
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 422 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 50.0 bits (114), Expect = 1e-05
Identities = 35/150 (23%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 83 ENATSLSLMIDSLLATYDRDSPP---DSKIVVNLTLHLRHAN-IRESESTVRIQADLQMN 250
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 251 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 421
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 422 IKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
RL I M L+++P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 49.6 bits (113), Expect = 2e-05
Identities = 40/171 (23%), Positives = 71/171 (41%), Gaps = 7/171 (4%)
Frame = +2
Query: 50 LTCAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESES 217
+ C S E N + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 218 TVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 388
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 389 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDF 541
R+ +G+V + R+ + M L +P D Q CT + S + D ++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 49.2 bits (112), Expect = 2e-05
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 497 FKFGS 511
+ S
Sbjct: 188 MQLES 192
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 49.2 bits (112), Expect = 2e-05
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 497 FKFGS 511
+ S
Sbjct: 188 MQLES 192
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 49.2 bits (112), Expect = 2e-05
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 497 FKFGS 511
+ S
Sbjct: 188 MQLES 192
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 497 FKFGS 511
+ S
Sbjct: 188 MQLES 192
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 497 FKFGS 511
+ S
Sbjct: 188 MQLES 192
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 373
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINELVDVGKS 131
Query: 374 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 520
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 497 FKFGS 511
+ S
Sbjct: 188 MQLES 192
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 497 FKFGS 511
+ S
Sbjct: 188 MQLES 192
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ ++ E+ R+ L+ W D RL+++ S + +
Sbjct: 69 PPVNVTCNIFIN-SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSI 127
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N D R+S NG V + RL ++ M L N+P D+QTCT
Sbjct: 128 WKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCT 187
Query: 497 FKFGS 511
+ S
Sbjct: 188 MQLES 192
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 48.4 bits (110), Expect = 4e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 373
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 374 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 520
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 48.4 bits (110), Expect = 4e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 373
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 78 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 137
Query: 374 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 520
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 138 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 186
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 48.4 bits (110), Expect = 4e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 373
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 374 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 520
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 48.4 bits (110), Expect = 4e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 373
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 374 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 520
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 48.4 bits (110), Expect = 4e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 373
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 374 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 520
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 48.4 bits (110), Expect = 4e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 373
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 374 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 520
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 48.4 bits (110), Expect = 4e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 373
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 374 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 520
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 48.4 bits (110), Expect = 4e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 373
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 374 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 520
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 48.4 bits (110), Expect = 4e-05
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 373
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 374 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMH 520
+ + G V K L + T S+ + N+P D+Q C+ F S +H
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH 180
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 48.0 bits (109), Expect = 5e-05
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 7/155 (4%)
Frame = +2
Query: 92 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 259
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 260 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 430
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 431 LDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
L I+ +QL N+P D +C F S + + M
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 48.0 bits (109), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 95 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 262
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 263 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 433
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 434 DISTPISMQLDNWPNDMQTCTFKFGS 511
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 95 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 262
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 263 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 433
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 434 DISTPISMQLDNWPNDMQTCTFKFGS 511
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 95 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 262
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 263 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 433
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 434 DISTPISMQLDNWPNDMQTCTFKFGS 511
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 95 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 262
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 263 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 433
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 434 DISTPISMQLDNWPNDMQTCTFKFGS 511
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.0 bits (109), Expect = 5e-05
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Frame = +2
Query: 95 SLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQMNWIDK 262
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 263 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 433
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 434 DISTPISMQLDNWPNDMQTCTFKFGS 511
I+ M+L N+P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 48.0 bits (109), Expect = 5e-05
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 7/155 (4%)
Frame = +2
Query: 92 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 259
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 260 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 430
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 431 LDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
L I+ +QL N+P D +C F S + + M
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 48.0 bits (109), Expect = 5e-05
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 7/155 (4%)
Frame = +2
Query: 92 TSLSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWID 259
T ++L+++ LL YD+ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 260 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 430
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 431 LDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
L I+ +QL N+P D +C F S + + M
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 181
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 47.6 bits (108), Expect = 6e-05
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Frame = +2
Query: 59 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 217
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 218 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 379
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 47.6 bits (108), Expect = 6e-05
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Frame = +2
Query: 59 AIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLHLRHA-NIRESES 217
A+ C A + ++D LL Y+ R + S+++ + L L L ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 218 TVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 379
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 8/151 (5%)
Frame = +2
Query: 107 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 271
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 272 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 442
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 443 TPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
M+L ++P D C KFGS + M
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 8/151 (5%)
Frame = +2
Query: 107 MIDSLLATYD-RDSP----PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLS 271
++DSLL YD R P P +++ ++ + + + E + + WIDKRL
Sbjct: 51 ILDSLLDGYDNRLRPGFGGPVTEVKTDIYV-TSFGPVSDVEMEYTMDVFFRQTWIDKRLK 109
Query: 272 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRLDIS 442
++ + ++W PD N + + + R+ NG++ + RL IS
Sbjct: 110 YDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTIS 169
Query: 443 TPISMQLDNWPNDMQTCTFKFGSRMHXXDXM 535
M+L ++P D C KFGS + M
Sbjct: 170 AECPMRLVDFPMDGHACPLKFGSYAYPKSEM 200
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 80 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 247
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 248 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 418
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 419 WIKRLDISTPISMQLDNWPNDMQTC 493
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 80 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 247
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 248 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 418
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 419 WIKRLDISTPISMQLDNWPNDMQTC 493
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 80 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 247
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 248 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 418
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 419 WIKRLDISTPISMQLDNWPNDMQTC 493
+ RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +2
Query: 80 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 247
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 248 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 418
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 419 WIKRLDISTPISMQLDNWPNDMQTC 493
+ RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 45.2 bits (102), Expect = 3e-04
Identities = 39/171 (22%), Positives = 71/171 (41%), Gaps = 7/171 (4%)
Frame = +2
Query: 50 LTCAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESES 217
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 218 TVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 388
+ Q +W DKRLS++ + +++L PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 389 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDF 541
R+ +G+V + R+ + M L +P D Q CT + S + D ++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 373
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 374 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 373
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 374 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 197 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 373
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 374 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
+ R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 77 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 241
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 242 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 409
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDF 541
+V + R+ + +M L +P D QTC + S + + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 77 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 241
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 242 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 409
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDF 541
+V + R+ + +M L +P D QTC + S + + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 77 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 241
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 242 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 409
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDF 541
+V + R+ + +M L +P D QTC + S + + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 77 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 241
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 242 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 409
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDF 541
+V + R+ + +M L +P D QTC + S + + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 77 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 241
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 242 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 409
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDF 541
+V + R+ + +M L +P D QTC + S + + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 44.4 bits (100), Expect = 6e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 7/135 (5%)
Frame = +2
Query: 110 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 277
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 278 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 448
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 449 ISMQLDNWPNDMQTC 493
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 44.4 bits (100), Expect = 6e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 7/135 (5%)
Frame = +2
Query: 110 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 277
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 278 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 448
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 449 ISMQLDNWPNDMQTC 493
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 44.4 bits (100), Expect = 6e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 7/135 (5%)
Frame = +2
Query: 110 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 277
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 278 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 448
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 449 ISMQLDNWPNDMQTC 493
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 77 ECENATSLSLM-IDSLLATYDRDSPPD---SKIVVNLTLHLRH-ANIRESESTVRIQADL 241
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 242 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 409
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 410 SVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDF 541
+V + R+ + +M L +P D QTC + S + + ++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 43.6 bits (98), Expect = 0.001
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 497 FKFGS 511
+ S
Sbjct: 147 MQLES 151
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 43.6 bits (98), Expect = 0.001
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ ++I ++ R+ L+ W D RLS+ S + +
Sbjct: 28 PPVNVTCNIFIN-SFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSI 86
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N + R+ NG+V + RL + M L N+P D+QTCT
Sbjct: 87 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCT 146
Query: 497 FKFGS 511
+ S
Sbjct: 147 MQLES 151
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 497 FKFGS 511
+ S
Sbjct: 187 MQLES 191
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 98 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 265
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 266 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 436
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 98 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 265
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 266 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 436
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 98 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 265
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 266 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 436
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 497 FKFGS 511
+ S
Sbjct: 187 MQLES 191
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 98 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 265
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125
Query: 266 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 436
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Frame = +2
Query: 149 PDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERL 325
P + N+ ++ +I E+ R+ L+ W D RL+++ S + +
Sbjct: 68 PPVNVTCNIFIN-SFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSI 126
Query: 326 WRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCT 496
W+PD+ N + R+ NG+V + RL ++ M L N+P D+QTC
Sbjct: 127 WKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCI 186
Query: 497 FKFGS 511
+ S
Sbjct: 187 MQLES 191
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 4/100 (4%)
Frame = +2
Query: 224 RIQADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 391
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 392 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
R+S NG+V + R+ ++ M L N+P D+QTC + S
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 103
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/155 (21%), Positives = 64/155 (41%), Gaps = 7/155 (4%)
Frame = +2
Query: 98 LSLMIDSLLATYDRDSPPDSKI---VVNLTLHLRHAN-IRESESTVRIQADLQMNWIDKR 265
++ +++SLL YD PD + V+ +++ + I W D R
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSR 123
Query: 266 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLD 436
L +N+ ++W PD N+ + A R+ N+G V + RL
Sbjct: 124 LKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLT 183
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGSRMHXXDXMDF 541
I+ +QL N+P D +C +F S + + +++
Sbjct: 184 INAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEY 218
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/145 (22%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Frame = +2
Query: 98 LSLMIDSLLATYDRDSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQM----NWIDKR 265
+++++++LL YD PD + L + N + + ++ + + W D+R
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRR 125
Query: 266 LSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKRLD 436
L +N+ ++W PD N+ A R+ N+G V + RL
Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLRLT 185
Query: 437 ISTPISMQLDNWPNDMQTCTFKFGS 511
I +QL N+P D +C +F S
Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSS 210
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 34.3 bits (75), Expect = 0.62
Identities = 18/63 (28%), Positives = 28/63 (44%)
Frame = +2
Query: 323 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFK 502
LW +A A + +A + ++G V W + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 503 FGS 511
FGS
Sbjct: 85 FGS 87
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 33.5 bits (73), Expect = 1.1
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Frame = +2
Query: 371 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMQTCTFKFGS 511
GD+A+ +A + ++G V W + S+ + +P D Q CT KFGS
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGS 110
>U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated protein
protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.8
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 398 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 264
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.8
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 398 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 264
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.8
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 398 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 264
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ10499 fis, clone NT2RP2000346, weakly similar to
MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD116.
).
Length = 674
Score = 31.1 bits (67), Expect = 5.8
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -1
Query: 398 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 264
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 7.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 272 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 433
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 272 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 433
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 7.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 272 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 433
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 272 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 433
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 7.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 272 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 433
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,731,570
Number of Sequences: 237096
Number of extensions: 2569229
Number of successful extensions: 7512
Number of sequences better than 10.0: 187
Number of HSP's better than 10.0 without gapping: 6224
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7285
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11825849886
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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