Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP16_FL5_E21
(819 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 62 2e-09
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 60 7e-09
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 60 7e-09
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 60 7e-09
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 60 7e-09
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 60 7e-09
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 60 7e-09
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 56 1e-07
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 56 2e-07
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 56 2e-07
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 56 2e-07
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 56 2e-07
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 56 2e-07
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 56 2e-07
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 56 2e-07
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 55 4e-07
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 55 4e-07
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 54 5e-07
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 54 5e-07
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 54 8e-07
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 54 8e-07
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 54 8e-07
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 54 8e-07
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 54 8e-07
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 53 1e-06
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 53 1e-06
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 53 1e-06
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 53 1e-06
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 53 1e-06
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 52 3e-06
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 52 3e-06
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 52 3e-06
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 52 3e-06
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 52 3e-06
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 52 3e-06
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 52 3e-06
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 52 3e-06
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 52 3e-06
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 52 3e-06
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 52 3e-06
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 52 3e-06
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 52 3e-06
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 52 3e-06
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 52 3e-06
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 52 3e-06
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 52 3e-06
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 52 3e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 51 4e-06
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 50 1e-05
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 50 1e-05
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 50 1e-05
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 50 1e-05
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 50 1e-05
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 50 1e-05
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 50 1e-05
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 50 1e-05
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 50 1e-05
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 50 1e-05
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 50 1e-05
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 50 1e-05
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 49 2e-05
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 48 3e-05
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 48 3e-05
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 48 3e-05
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 48 3e-05
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 48 4e-05
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 48 4e-05
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 48 4e-05
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 48 4e-05
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 48 4e-05
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 48 4e-05
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 48 4e-05
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 48 4e-05
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 48 4e-05
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 48 4e-05
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 48 4e-05
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 48 4e-05
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 48 4e-05
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 48 5e-05
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 48 5e-05
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 48 5e-05
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 48 5e-05
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 48 5e-05
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 47 9e-05
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 47 9e-05
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 47 9e-05
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 47 9e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 46 1e-04
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 46 2e-04
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 46 2e-04
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 46 2e-04
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 46 2e-04
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 46 2e-04
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 46 2e-04
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 46 2e-04
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 46 2e-04
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 45 3e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 45 4e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 45 4e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 45 4e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 45 4e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 44 7e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 44 7e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 44 7e-04
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 44 9e-04
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 44 9e-04
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 44 9e-04
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 44 9e-04
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 44 9e-04
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 44 9e-04
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 44 9e-04
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 44 9e-04
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 44 9e-04
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 43 0.001
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 43 0.002
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 42 0.002
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 42 0.002
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 42 0.004
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 42 0.004
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 42 0.004
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 41 0.005
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 41 0.005
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 41 0.005
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 41 0.005
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 41 0.005
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 41 0.006
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.006
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.006
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.006
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.006
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 41 0.006
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 40 0.008
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 40 0.014
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 40 0.014
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 38 0.033
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 38 0.033
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 38 0.033
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 38 0.033
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 37 0.076
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 36 0.18
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 36 0.18
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 6.6
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 6.6
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 6.6
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 6.6
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 6.6
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/158 (26%), Positives = 70/158 (44%), Gaps = 8/158 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 409
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 410 VSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
V +NGSV W+ + +++ P D Q C K R
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 171
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 60.5 bits (140), Expect = 7e-09
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 9/159 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
V +NGSV W+ + +++ P D Q C K R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 60.5 bits (140), Expect = 7e-09
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 9/159 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
V +NGSV W+ + +++ P D Q C K R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 60.5 bits (140), Expect = 7e-09
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 9/159 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
V +NGSV W+ + +++ P D Q C K R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 60.5 bits (140), Expect = 7e-09
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 9/159 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
V +NGSV W+ + +++ P D Q C K R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 60.5 bits (140), Expect = 7e-09
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 9/159 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
V +NGSV W+ + +++ P D Q C K R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 60.5 bits (140), Expect = 7e-09
Identities = 43/159 (27%), Positives = 71/159 (44%), Gaps = 9/159 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
V +NGSV W+ + +++ P D Q C K R
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 172
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 3/119 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
D+VL N A T V +NGSV W+ + +++ P D Q C K R
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFR 125
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 56.0 bits (129), Expect = 2e-07
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V W + +M + P D Q C K
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 56.0 bits (129), Expect = 2e-07
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V W + +M + P D Q C K
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 135
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 56.0 bits (129), Expect = 2e-07
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V W + +M + P D Q C K
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 56.0 bits (129), Expect = 2e-07
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V W + +M + P D Q C K
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 56.0 bits (129), Expect = 2e-07
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V W + +M + P D Q C K
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 56.0 bits (129), Expect = 2e-07
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V W + +M + P D Q C K
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 56.0 bits (129), Expect = 2e-07
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V W + +M + P D Q C K
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMK 170
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V W+ + S+ + P D Q C K
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMK 200
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 54.8 bits (126), Expect = 4e-07
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V W+ + S+ + P D Q C K
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMK 200
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Frame = +2
Query: 152 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 325
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 326 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDXRPNDM 499
++E +W PDVVLLN D AL VS++GSV W + S+Q+ P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 500 QTC 508
Q C
Sbjct: 163 QNC 165
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Frame = +2
Query: 152 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 325
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 326 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDXRPNDM 499
++E +W PDVVLLN D AL VS++GSV W + S+Q+ P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 500 QTC 508
Q C
Sbjct: 163 QNC 165
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 53.6 bits (123), Expect = 8e-07
Identities = 42/166 (25%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 217
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 218 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 394
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 395 AL----RARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
A+ + + G ++W + + + P D Q C K+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKL 166
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 53.6 bits (123), Expect = 8e-07
Identities = 42/166 (25%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 217
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 218 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 394
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 395 AL----RARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
A+ + + G ++W + + + P D Q C K+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKL 166
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 53.6 bits (123), Expect = 8e-07
Identities = 42/166 (25%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 217
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 218 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 394
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 395 AL----RARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
A+ + + G ++W + + + P D Q C K+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKL 166
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 53.6 bits (123), Expect = 8e-07
Identities = 42/166 (25%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 217
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 218 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 394
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 395 AL----RARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
A+ + + G ++W + + + P D Q C K+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKL 166
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 53.6 bits (123), Expect = 8e-07
Identities = 42/166 (25%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 217
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 218 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 394
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 395 AL----RARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
A+ + + G ++W + + + P D Q C K+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKL 166
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 6/138 (4%)
Frame = +2
Query: 122 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 286
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 287 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 463
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 464 ISMQLDXRPNDMQTCMFK 517
++ + P D+Q C K
Sbjct: 170 CTIDVTFFPFDLQNCSMK 187
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 6/138 (4%)
Frame = +2
Query: 122 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 286
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 287 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 463
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 464 ISMQLDXRPNDMQTCMFK 517
++ + P D+Q C K
Sbjct: 170 CTIDVTFFPFDLQNCSMK 187
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 6/138 (4%)
Frame = +2
Query: 122 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 286
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 287 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 463
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 464 ISMQLDXRPNDMQTCMFK 517
++ + P D+Q C K
Sbjct: 170 CTIDVTFFPFDLQNCSMK 187
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 53.2 bits (122), Expect = 1e-06
Identities = 40/125 (32%), Positives = 62/125 (49%), Gaps = 6/125 (4%)
Frame = +2
Query: 152 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 325
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 326 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDXRPN 493
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 494 DMQTC 508
D Q C
Sbjct: 161 DWQNC 165
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 6/138 (4%)
Frame = +2
Query: 122 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 286
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 287 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 463
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 464 ISMQLDXRPNDMQTCMFK 517
++ + P D+Q C K
Sbjct: 170 CTIDVTFFPFDLQNCSMK 187
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/151 (24%), Positives = 66/151 (43%), Gaps = 10/151 (6%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 259
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 260 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 424
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++W + M + P D Q C K
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLK 175
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 174
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 145
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/151 (24%), Positives = 66/151 (43%), Gaps = 10/151 (6%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 259
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 260 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 424
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++W + M + P D Q C K
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLK 175
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 175
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 52.0 bits (119), Expect = 3e-06
Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 6/138 (4%)
Frame = +2
Query: 122 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 286
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 287 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 463
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 464 ISMQLDXRPNDMQTCMFK 517
++ + P D+Q C K
Sbjct: 170 CTIDVTFFPFDLQNCSMK 187
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 174
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 175
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/151 (24%), Positives = 66/151 (43%), Gaps = 10/151 (6%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 259
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 260 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 424
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++W + M + P D Q C K
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLK 175
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 176
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 175
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 52.0 bits (119), Expect = 3e-06
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
V+WI + + + P D Q C K
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 170
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/151 (24%), Positives = 66/151 (43%), Gaps = 10/151 (6%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 259
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 260 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 424
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++W + M + P D Q C K
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLK 175
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 51.2 bits (117), Expect = 4e-06
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 7/133 (5%)
Frame = +2
Query: 62 LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RES 226
LL A+ A+ N L+ D L+ YD P + VVN++L L N+ E
Sbjct: 11 LLLLAVCLGAQGRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNER 68
Query: 227 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYAL 400
E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + + L
Sbjct: 69 EEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDL 128
Query: 401 RARVSNNGSVSWI 439
+ + S+ WI
Sbjct: 129 QLSQEDGQSIEWI 141
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 8/137 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 286
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 287 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDIS 457
W+ ++ G V S +WRPD+VL N + AL VS +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 458 TPISMQLDXRPNDMQTC 508
+ S+ + P D Q C
Sbjct: 151 SACSISVTYFPFDWQNC 167
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 8/137 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 286
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 287 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDIS 457
W+ ++ G V S +WRPD+VL N + AL VS +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 458 TPISMQLDXRPNDMQTC 508
+ S+ + P D Q C
Sbjct: 151 SACSISVTYFPFDWQNC 167
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 7/139 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWIKRLDIST 460
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V W +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 461 PISMQLDXRPNDMQTCMFK 517
S+ + P D Q C K
Sbjct: 160 SCSIDVTFFPFDQQNCTMK 178
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 7/139 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWIKRLDIST 460
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V W +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 461 PISMQLDXRPNDMQTCMFK 517
S+ + P D Q C K
Sbjct: 160 SCSIDVTFFPFDQQNCTMK 178
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 7/139 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWIKRLDIST 460
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V W +
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 134
Query: 461 PISMQLDXRPNDMQTCMFK 517
S+ + P D Q C K
Sbjct: 135 SCSIDVTFFPFDQQNCTMK 153
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Frame = +2
Query: 164 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 337
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 338 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+W P++VL N G Y V GSV+W+ + ++++ P D Q C
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNC 162
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 7/139 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWIKRLDIST 460
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V W +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 461 PISMQLDXRPNDMQTCMFK 517
S+ + P D Q C K
Sbjct: 160 SCSIDVTFFPFDQQNCTMK 178
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 5/93 (5%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 418
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNA---VGDFQVTTKTKALLKY 140
Query: 419 NGSVSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
G V+WI + + + P D Q C K
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMK 173
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 7/139 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWIKRLDIST 460
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V W +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 461 PISMQLDXRPNDMQTCMFK 517
S+ + P D Q C K
Sbjct: 160 SCSIDVTFFPFDQQNCTMK 178
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 7/139 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWIKRLDIST 460
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V W +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 461 PISMQLDXRPNDMQTCMFK 517
S+ + P D Q C K
Sbjct: 160 SCSIDVTFFPFDQQNCTMK 178
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 7/139 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGSVSWIKRLDIST 460
W+ ++ T + + SE +WRPD+VL NA A + +A + ++G V W +
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKS 159
Query: 461 PISMQLDXRPNDMQTCMFK 517
S+ + P D Q C K
Sbjct: 160 SCSIDVTFFPFDQQNCTMK 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Frame = +2
Query: 164 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 337
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 338 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+W P++VL N G Y V GSV+W+ + ++++ P D Q C
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNC 162
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 48.8 bits (111), Expect = 2e-05
Identities = 42/161 (26%), Positives = 66/161 (40%), Gaps = 4/161 (2%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-NIRES 226
+ L C+ A+ E L+ S R + S++V V L + L ++ E
Sbjct: 14 FGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHER 73
Query: 227 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 400
E + L W D RL+W E+ + S+ +W PDVVL N A +
Sbjct: 74 EQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYS 133
Query: 401 RARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
A VS +GS+ W+ + +++ P D Q C K R
Sbjct: 134 NAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 48.4 bits (110), Expect = 3e-05
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Frame = +2
Query: 146 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 307
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 308 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 484
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 485 RPNDMQTCMFK 517
P D Q C K
Sbjct: 158 FPFDWQNCSLK 168
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 48.4 bits (110), Expect = 3e-05
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Frame = +2
Query: 146 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 307
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 308 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 484
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 485 RPNDMQTCMFK 517
P D Q C K
Sbjct: 158 FPFDWQNCSLK 168
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 48.4 bits (110), Expect = 3e-05
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Frame = +2
Query: 146 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 307
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 308 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 484
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 485 RPNDMQTCMFK 517
P D Q C K
Sbjct: 158 FPFDWQNCSLK 168
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 48.4 bits (110), Expect = 3e-05
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Frame = +2
Query: 146 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 307
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 308 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDX 484
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 485 RPNDMQTCMFK 517
P D Q C K
Sbjct: 158 FPFDWQNCSLK 168
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 48.0 bits (109), Expect = 4e-05
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
DVVL N A + A VS +GS+ W+ + +++ P D Q C K R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 48.0 bits (109), Expect = 4e-05
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
DVVL N A + A VS +GS+ W+ + +++ P D Q C K R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 48.0 bits (109), Expect = 4e-05
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
DVVL N A + A VS +GS+ W+ + +++ P D Q C K R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/170 (23%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
++ R+ +G+V + R+ + M L P D Q C ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/170 (23%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
++ R+ +G+V + R+ + M L P D Q C ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/170 (23%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
++ R+ +G+V + R+ + M L P D Q C ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/170 (23%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
++ R+ +G+V + R+ + M L P D Q C ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/170 (23%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
++ R+ +G+V + R+ + M L P D Q C ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/170 (23%), Positives = 71/170 (41%), Gaps = 10/170 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
++ R+ +G+V + R+ + M L P D Q C ++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 178
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 48.0 bits (109), Expect = 4e-05
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
DVVL N A + A VS +GS+ W+ + +++ P D Q C K R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 48.0 bits (109), Expect = 4e-05
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
DVVL N A + A VS +GS+ W+ + +++ P D Q C K R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 48.0 bits (109), Expect = 4e-05
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
DVVL N A + A VS +GS+ W+ + +++ P D Q C K R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 48.0 bits (109), Expect = 4e-05
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 3/119 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKVR 523
DVVL N A + A VS +GS+ W+ + +++ P D Q C K R
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFR 174
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 47.6 bits (108), Expect = 5e-05
Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 44 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 208
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 209 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 376
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 377 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+ + + +G ++W + + + P D Q C
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQC 169
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 47.6 bits (108), Expect = 5e-05
Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 44 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 208
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 209 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 376
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 377 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+ + + +G ++W + + + P D Q C
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQC 169
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 47.6 bits (108), Expect = 5e-05
Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 44 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 208
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 209 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 376
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 377 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+ + + +G ++W + + + P D Q C
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQC 169
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 47.6 bits (108), Expect = 5e-05
Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 44 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 208
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 209 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 376
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 377 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+ + + +G ++W + + + P D Q C
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQC 169
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 47.6 bits (108), Expect = 5e-05
Identities = 39/165 (23%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 44 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 208
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 209 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 376
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 377 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+ + + +G ++W + + + P D Q C
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQC 169
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 46.8 bits (106), Expect = 9e-05
Identities = 40/150 (26%), Positives = 65/150 (43%), Gaps = 10/150 (6%)
Frame = +2
Query: 89 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 253
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 254 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 418
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 419 NGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+G+V W + + + P D Q C
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHC 168
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 46.8 bits (106), Expect = 9e-05
Identities = 40/150 (26%), Positives = 65/150 (43%), Gaps = 10/150 (6%)
Frame = +2
Query: 89 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 253
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 254 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 418
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 419 NGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+G+V W + + + P D Q C
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHC 168
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 46.8 bits (106), Expect = 9e-05
Identities = 40/150 (26%), Positives = 65/150 (43%), Gaps = 10/150 (6%)
Frame = +2
Query: 89 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 253
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 254 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 418
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 419 NGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+G+V W + + + P D Q C
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHC 168
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 46.8 bits (106), Expect = 9e-05
Identities = 40/150 (26%), Positives = 65/150 (43%), Gaps = 10/150 (6%)
Frame = +2
Query: 89 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 253
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 254 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 418
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 419 NGSVSWIKRLDISTPISMQLDXRPNDMQTC 508
+G+V W + + + P D Q C
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHC 168
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/148 (22%), Positives = 66/148 (44%), Gaps = 7/148 (4%)
Frame = +2
Query: 86 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 253
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 254 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 424
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTC 508
++W + + + P D Q C
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQC 163
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 431 SWIKRLDISTPISMQLDXRPNDMQTC 508
+ K + + + ++ + P D Q C
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNC 176
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/85 (29%), Positives = 38/85 (44%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 434 WIKRLDISTPISMQLDXRPNDMQTC 508
L T + +L P D C
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNC 170
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 431 SWIKRLDISTPISMQLDXRPNDMQTC 508
+ K + + + ++ + P D Q C
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNC 105
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 431 SWIKRLDISTPISMQLDXRPNDMQTC 508
+ K + + + ++ + P D Q C
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNC 191
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 431 SWIKRLDISTPISMQLDXRPNDMQTC 508
+ K + + + ++ + P D Q C
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNC 191
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 431 SWIKRLDISTPISMQLDXRPNDMQTC 508
+ K + + + ++ + P D Q C
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNC 191
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/85 (29%), Positives = 38/85 (44%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 434 WIKRLDISTPISMQLDXRPNDMQTC 508
L T + +L P D C
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNC 171
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/85 (29%), Positives = 38/85 (44%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 434 WIKRLDISTPISMQLDXRPNDMQTC 508
L T + +L P D C
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNC 170
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/85 (29%), Positives = 38/85 (44%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 434 WIKRLDISTPISMQLDXRPNDMQTC 508
L T + +L P D C
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNC 170
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 44.8 bits (101), Expect = 4e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 262
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 263 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 433
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 434 WIKRLDISTPISMQLDXRPNDMQTC 508
+ RL + S+ L P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 44.8 bits (101), Expect = 4e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 262
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 263 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 433
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 434 WIKRLDISTPISMQLDXRPNDMQTC 508
+ RL + S+ L P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 44.8 bits (101), Expect = 4e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 262
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 263 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 433
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 434 WIKRLDISTPISMQLDXRPNDMQTC 508
+ RL + S+ L P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 44.8 bits (101), Expect = 4e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 262
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 263 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 433
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 434 WIKRLDISTPISMQLDXRPNDMQTC 508
+ RL + S+ L P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 44.0 bits (99), Expect = 7e-04
Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 7/136 (5%)
Frame = +2
Query: 125 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 292
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 293 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 463
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 464 ISMQLDXRPNDMQTCM 511
M L P D Q CM
Sbjct: 164 CDMDLAKYPMDEQECM 179
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 44.0 bits (99), Expect = 7e-04
Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 7/136 (5%)
Frame = +2
Query: 125 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 292
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 293 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 463
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 464 ISMQLDXRPNDMQTCM 511
M L P D Q CM
Sbjct: 164 CDMDLAKYPMDEQECM 179
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 44.0 bits (99), Expect = 7e-04
Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 7/136 (5%)
Frame = +2
Query: 125 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 292
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 293 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 463
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 464 ISMQLDXRPNDMQTCM 511
M L P D Q CM
Sbjct: 164 CDMDLAKYPMDEQECM 179
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 43.6 bits (98), Expect = 9e-04
Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++ + + + P D+Q C K
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLK 144
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 43.6 bits (98), Expect = 9e-04
Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++ + + + P D+Q C K
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLK 167
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 43.6 bits (98), Expect = 9e-04
Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++ + + + P D+Q C K
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLK 167
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 43.6 bits (98), Expect = 9e-04
Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++ + + + P D+Q C K
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLK 167
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 43.6 bits (98), Expect = 9e-04
Identities = 36/159 (22%), Positives = 65/159 (40%), Gaps = 7/159 (4%)
Frame = +2
Query: 65 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 232
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 233 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 403
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 404 ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
R+ +G+V + R+ + M L P D Q C ++
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 179
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 43.6 bits (98), Expect = 9e-04
Identities = 21/88 (23%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 431 SWIKRLDISTPISMQLDXRPNDMQTCMF 514
+ K + +++ ++ + P D Q C F
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTF 178
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 43.6 bits (98), Expect = 9e-04
Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = +2
Query: 248 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 424
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTC 508
+ + K + + + ++ + P D Q C
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNC 176
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 43.6 bits (98), Expect = 9e-04
Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = +2
Query: 248 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 424
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTC 508
+ + K + + + ++ + P D Q C
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNC 161
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 43.6 bits (98), Expect = 9e-04
Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++ + + + P D+Q C K
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLK 167
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 43.2 bits (97), Expect = 0.001
Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 431 SWIKRLDISTPISMQLDXRPNDMQTCMF 514
+ K + +++ + + P D Q C F
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTF 178
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/159 (22%), Positives = 64/159 (40%), Gaps = 7/159 (4%)
Frame = +2
Query: 65 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 232
+ C S E N + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 233 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 403
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 404 ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
R+ +G+V + R+ + M L P D Q C ++
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 179
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 42.3 bits (95), Expect = 0.002
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++ + + + P D+Q C K
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLK 167
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 42.3 bits (95), Expect = 0.002
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 428 VSWIKRLDISTPISMQLDXRPNDMQTCMFK 517
++ + + + P D+Q C K
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLK 167
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 41.5 bits (93), Expect = 0.004
Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 XRPNDMQTCMFKV 520
P D+QTC ++
Sbjct: 178 NFPMDVQTCTMQL 190
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 41.5 bits (93), Expect = 0.004
Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 XRPNDMQTCMFKV 520
P D+QTC ++
Sbjct: 178 NFPMDVQTCTMQL 190
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 41.5 bits (93), Expect = 0.004
Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 XRPNDMQTCMFKV 520
P D+QTC ++
Sbjct: 178 NFPMDVQTCTMQL 190
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 41.1 bits (92), Expect = 0.005
Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 XRPNDMQTCMFKV 520
P D+QTC ++
Sbjct: 178 NFPMDVQTCTMQL 190
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 41.1 bits (92), Expect = 0.005
Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 XRPNDMQTCMFKV 520
P D+QTC ++
Sbjct: 178 NFPMDVQTCTMQL 190
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 41.1 bits (92), Expect = 0.005
Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 XRPNDMQTCMFKV 520
P D+QTC ++
Sbjct: 178 NFPMDVQTCTMQL 190
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 41.1 bits (92), Expect = 0.005
Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 XRPNDMQTCMFKV 520
P D+QTC ++
Sbjct: 178 NFPMDVQTCTMQL 190
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 41.1 bits (92), Expect = 0.005
Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 XRPNDMQTCMFKV 520
P D+QTC ++
Sbjct: 178 NFPMDVQTCTMQL 190
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 40.7 bits (91), Expect = 0.006
Identities = 38/152 (25%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
+V + R+ + +M L P D QTC ++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 40.7 bits (91), Expect = 0.006
Identities = 38/152 (25%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
+V + R+ + +M L P D QTC ++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 40.7 bits (91), Expect = 0.006
Identities = 38/152 (25%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
+V + R+ + +M L P D QTC ++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 40.7 bits (91), Expect = 0.006
Identities = 38/152 (25%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
+V + R+ + +M L P D QTC ++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 40.7 bits (91), Expect = 0.006
Identities = 38/152 (25%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
+V + R+ + +M L P D QTC ++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 40.7 bits (91), Expect = 0.006
Identities = 38/152 (25%), Positives = 70/152 (46%), Gaps = 9/152 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
+V + R+ + +M L P D QTC ++
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQL 178
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 40.3 bits (90), Expect = 0.008
Identities = 45/176 (25%), Positives = 76/176 (43%), Gaps = 15/176 (8%)
Frame = +2
Query: 38 LYYSCYXFLLTCAIASAAEC-ENAT---SLSLMIDSLLAT---YDRESPPDSK-IVVNLT 193
LY S + A + AE +AT S S +D L+ YD P+ K VN++
Sbjct: 9 LYLSGAIVFFSLAASKEAEAARSATKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVS 68
Query: 194 LHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVL 361
++ +I E+ R+ L+ W D RL++N S + +W+PD+
Sbjct: 69 CNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFF 128
Query: 362 LNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
N + R+S NG+V + R+ ++ M L P D+QTC+ ++
Sbjct: 129 ANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQL 184
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 39.5 bits (88), Expect = 0.014
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 4/107 (3%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 388
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 389 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
+ R+S NG+V + R+ ++ M L P D+QTC+ ++
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQL 184
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 39.5 bits (88), Expect = 0.014
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 4/107 (3%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 388
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 389 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
+ R+S NG+V + R+ ++ M L P D+QTC+ ++
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQL 184
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 38.3 bits (85), Expect = 0.033
Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 482 XRPNDMQTCMFKV 520
P D+QTC+ ++
Sbjct: 177 NFPMDVQTCIMQL 189
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 38.3 bits (85), Expect = 0.033
Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 482 XRPNDMQTCMFKV 520
P D+QTC+ ++
Sbjct: 177 NFPMDVQTCIMQL 189
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 38.3 bits (85), Expect = 0.033
Identities = 35/159 (22%), Positives = 64/159 (40%), Gaps = 7/159 (4%)
Frame = +2
Query: 65 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 232
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 233 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 403
+ Q +W DKRLS++ + +++L PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 404 ARVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
R+ +G+V + R+ + M L P D Q C ++
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEI 179
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 38.3 bits (85), Expect = 0.033
Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 482 XRPNDMQTCMFKV 520
P D+QTC+ ++
Sbjct: 177 NFPMDVQTCIMQL 189
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 37.1 bits (82), Expect = 0.076
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 4/98 (4%)
Frame = +2
Query: 239 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 406
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDXRPNDMQTCMFKV 520
R+S NG+V + R+ ++ M L P D+QTC+ ++
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQL 101
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 35.9 bits (79), Expect = 0.18
Identities = 33/133 (24%), Positives = 56/133 (42%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 482 XRPNDMQTCMFKV 520
P D+QTC ++
Sbjct: 137 NFPMDIQTCTMQL 149
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 35.9 bits (79), Expect = 0.18
Identities = 33/133 (24%), Positives = 56/133 (42%), Gaps = 8/133 (6%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 482 XRPNDMQTCMFKV 520
P D+QTC ++
Sbjct: 137 NFPMDIQTCTMQL 149
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 6.6
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 287 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 448
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.6
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 287 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 448
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 6.6
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 287 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 448
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 6.6
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 287 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 448
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 6.6
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 287 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 448
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 107,525,835
Number of Sequences: 237096
Number of extensions: 2240615
Number of successful extensions: 5326
Number of sequences better than 10.0: 148
Number of HSP's better than 10.0 without gapping: 4943
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5204
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10203625794
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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