Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP15_FL5_D15
(802 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY290821-1|AAP42280.1| 348|Homo sapiens LYK5 protein protein. 166 9e-41
AK075005-1|BAC11349.1| 348|Homo sapiens protein ( Homo sapiens ... 166 9e-41
AK074771-1|BAC11197.1| 394|Homo sapiens protein ( Homo sapiens ... 166 9e-41
AF308302-1|AAG48269.1| 431|Homo sapiens serologically defined b... 166 9e-41
BC043641-1|AAH43641.1| 234|Homo sapiens LYK5 protein protein. 155 2e-37
BC090871-1|AAH90871.1| 377|Homo sapiens ALS2CR2 protein protein. 131 3e-30
BC008302-1|AAH08302.1| 418|Homo sapiens amyotrophic lateral scl... 131 3e-30
AY093697-1|AAM19143.1| 418|Homo sapiens ILP-interacting protein... 131 3e-30
AK027637-1|BAB55254.1| 418|Homo sapiens protein ( Homo sapiens ... 131 3e-30
AC007282-3|AAY14692.1| 418|Homo sapiens unknown protein. 131 3e-30
AB038950-1|BAB32500.1| 418|Homo sapiens amyotrophic lateral scl... 131 3e-30
DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress respon... 109 2e-23
BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress respon... 109 2e-23
AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress respon... 109 2e-23
AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase S... 98 3e-20
AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein. 98 3e-20
AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kina... 97 9e-20
AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein. 89 2e-17
AY629298-1|AAT65492.1| 476|Homo sapiens small intestine SPAK-li... 86 2e-16
U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor ... 81 5e-15
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 78 3e-14
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 78 4e-14
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 78 4e-14
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 78 4e-14
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 78 4e-14
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 77 6e-14
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 77 6e-14
AL117326-3|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 77 6e-14
AL117326-2|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 77 6e-14
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 77 6e-14
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 77 6e-14
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 77 6e-14
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 77 6e-14
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 77 6e-14
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 76 1e-13
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 76 2e-13
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 76 2e-13
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 76 2e-13
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 76 2e-13
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 76 2e-13
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 76 2e-13
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 75 2e-13
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 75 2e-13
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 75 2e-13
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 75 2e-13
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 75 2e-13
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 75 2e-13
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 75 2e-13
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 75 2e-13
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 75 2e-13
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 75 3e-13
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 75 4e-13
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 75 4e-13
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 75 4e-13
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 75 4e-13
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 75 4e-13
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 75 4e-13
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 75 4e-13
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 75 4e-13
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 75 4e-13
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 75 4e-13
AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2 ... 74 5e-13
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 73 9e-13
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 73 9e-13
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 73 9e-13
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 73 9e-13
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 73 9e-13
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 73 9e-13
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 73 9e-13
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 73 9e-13
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 73 9e-13
BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein. 70 1e-11
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 70 1e-11
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 70 1e-11
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 70 1e-11
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 70 1e-11
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 70 1e-11
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 70 1e-11
U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein. 69 3e-11
AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protei... 67 6e-11
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 67 8e-11
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 67 8e-11
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 67 8e-11
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 67 8e-11
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 67 8e-11
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 67 8e-11
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 67 8e-11
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 67 8e-11
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 67 8e-11
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 67 8e-11
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 66 1e-10
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 66 1e-10
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 66 1e-10
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 66 1e-10
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 66 1e-10
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 66 1e-10
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 66 1e-10
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 66 1e-10
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 66 1e-10
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 65 2e-10
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 65 2e-10
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 65 2e-10
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 65 2e-10
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 65 2e-10
AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens ... 63 1e-09
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 63 1e-09
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 63 1e-09
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 63 1e-09
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 63 1e-09
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 63 1e-09
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 63 1e-09
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 63 1e-09
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 63 1e-09
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 63 1e-09
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 63 1e-09
AY574905-1|AAT81414.1| 462|Homo sapiens regulated in COPD kinas... 62 2e-09
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 62 3e-09
AL732423-2|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 62 3e-09
AL732423-1|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 62 3e-09
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 62 3e-09
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 62 3e-09
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 62 3e-09
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 60 7e-09
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 60 7e-09
BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein. 60 7e-09
BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein. 60 7e-09
BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein. 60 7e-09
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 60 7e-09
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 60 7e-09
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 60 7e-09
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 60 7e-09
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 60 7e-09
AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein. 60 7e-09
AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein. 60 7e-09
AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein. 60 7e-09
AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein. 60 7e-09
AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein. 60 7e-09
AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein. 60 7e-09
AL121829-13|CAC15525.1| 451|Homo sapiens PTK6 protein. 60 7e-09
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 60 7e-09
AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein. 60 7e-09
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 60 7e-09
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 60 7e-09
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 60 9e-09
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 60 9e-09
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 60 9e-09
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 60 9e-09
BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein. 60 1e-08
BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein. 60 1e-08
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 60 1e-08
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 60 1e-08
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 60 1e-08
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 60 1e-08
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 60 1e-08
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 60 1e-08
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 59 2e-08
BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein. 59 2e-08
BC034673-1|AAH34673.1| 1332|Homo sapiens misshapen-like kinase 1... 59 2e-08
AY775058-1|AAV41830.1| 1312|Homo sapiens misshapen/NIKs-related ... 59 2e-08
AB041926-1|BAA94838.1| 1303|Homo sapiens GCK family kinase MINK-... 59 2e-08
AB035698-1|BAA90753.1| 1295|Homo sapiens Misshapen/NIK-related k... 59 2e-08
AY212247-1|AAO32626.1| 1239|Homo sapiens Ste20 group protein kin... 58 4e-08
AF096300-1|AAD16137.1| 1165|Homo sapiens HPK/GCK-like kinase HGK... 58 4e-08
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 58 5e-08
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 58 5e-08
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 58 5e-08
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 58 5e-08
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 58 5e-08
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 58 5e-08
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 58 5e-08
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 58 5e-08
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 58 5e-08
AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens ... 58 5e-08
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 58 5e-08
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 57 6e-08
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 57 6e-08
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 57 6e-08
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 57 6e-08
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 57 6e-08
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 57 6e-08
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 57 6e-08
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 57 6e-08
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 57 6e-08
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 57 6e-08
AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens ... 57 6e-08
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 57 6e-08
AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein. 57 6e-08
AB014587-1|BAA31662.1| 1175|Homo sapiens KIAA0687 protein protein. 57 6e-08
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 57 9e-08
BC150256-1|AAI50257.1| 1360|Homo sapiens TRAF2 and NCK interacti... 57 9e-08
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 57 9e-08
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 57 9e-08
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 57 9e-08
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 57 9e-08
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 57 9e-08
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 57 9e-08
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 57 9e-08
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 57 9e-08
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 57 9e-08
AF172271-1|AAF03789.1| 1268|Homo sapiens Traf2 and NCK interacti... 57 9e-08
AF172270-1|AAF03788.1| 1297|Homo sapiens Traf2 and NCK interacti... 57 9e-08
AF172269-1|AAF03787.1| 1323|Homo sapiens Traf2 and NCK interacti... 57 9e-08
AF172268-1|AAF03786.1| 1276|Homo sapiens Traf2 and NCK interacti... 57 9e-08
AF172267-1|AAF03785.1| 1352|Homo sapiens Traf2 and NCK interacti... 57 9e-08
AF172266-1|AAF03784.1| 1305|Homo sapiens Traf2 and NCK interacti... 57 9e-08
AF172265-1|AAF03783.1| 1331|Homo sapiens Traf2 and NCK interacti... 57 9e-08
AF172264-1|AAF03782.1| 1360|Homo sapiens Traf2 and NCK interacti... 57 9e-08
AB011123-1|BAA25477.2| 1385|Homo sapiens KIAA0551 protein protein. 57 9e-08
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 57 9e-08
AL358612-2|CAH73815.1| 197|Homo sapiens myosin IIIA protein. 56 1e-07
BX538345-1|CAD98108.1| 1582|Homo sapiens hypothetical protein pr... 56 2e-07
AY834276-1|AAV97884.1| 1042|Homo sapiens mitogen-activated prote... 55 3e-07
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 54 5e-07
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 54 5e-07
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 54 5e-07
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 54 5e-07
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 54 5e-07
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 54 5e-07
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 54 5e-07
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 54 5e-07
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 54 5e-07
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 54 5e-07
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 54 5e-07
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 54 5e-07
D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein. 54 6e-07
BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein. 54 6e-07
BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein. 54 6e-07
AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase ... 54 6e-07
AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-... 54 8e-07
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 54 8e-07
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 54 8e-07
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 53 1e-06
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 53 1e-06
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 53 1e-06
AL162724-8|CAH70253.1| 201|Homo sapiens NIMA (never in mitosis ... 53 1e-06
AL137846-12|CAI10882.1| 201|Homo sapiens NIMA (never in mitosis... 53 1e-06
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 53 1e-06
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 53 1e-06
AC005035-1|AAY14969.1| 1260|Homo sapiens unknown protein. 53 1e-06
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 53 1e-06
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 52 2e-06
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 52 2e-06
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 52 2e-06
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 52 2e-06
BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase... 52 2e-06
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 52 2e-06
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 52 2e-06
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 52 2e-06
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 52 2e-06
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 52 2e-06
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 52 2e-06
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 52 2e-06
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 52 2e-06
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 52 2e-06
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 52 2e-06
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 52 2e-06
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 52 2e-06
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 52 2e-06
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 52 3e-06
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 52 3e-06
AL162724-7|CAH70252.1| 222|Homo sapiens NIMA (never in mitosis ... 52 3e-06
AL162724-6|CAH70251.1| 220|Homo sapiens NIMA (never in mitosis ... 52 3e-06
AL162724-5|CAH70250.1| 219|Homo sapiens NIMA (never in mitosis ... 52 3e-06
AL162724-4|CAH70249.1| 207|Homo sapiens NIMA (never in mitosis ... 52 3e-06
AL137846-11|CAI10881.1| 222|Homo sapiens NIMA (never in mitosis... 52 3e-06
AL137846-10|CAI10880.1| 220|Homo sapiens NIMA (never in mitosis... 52 3e-06
AL137846-9|CAI10879.1| 219|Homo sapiens NIMA (never in mitosis ... 52 3e-06
AL137846-8|CAI10878.1| 207|Homo sapiens NIMA (never in mitosis ... 52 3e-06
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 52 3e-06
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 52 3e-06
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 52 3e-06
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 51 6e-06
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 51 6e-06
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 51 6e-06
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 51 6e-06
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 51 6e-06
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 51 6e-06
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 51 6e-06
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 51 6e-06
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 51 6e-06
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 51 6e-06
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 51 6e-06
BC014243-1|AAH14243.1| 1187|Homo sapiens tyrosine kinase 2 protein. 51 6e-06
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 51 6e-06
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 51 6e-06
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 51 6e-06
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 50 7e-06
AY549314-1|AAS37680.1| 1187|Homo sapiens tyrosine kinase 2 protein. 50 7e-06
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 50 7e-06
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 50 7e-06
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 50 7e-06
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 50 7e-06
BC112933-1|AAI12934.1| 387|Homo sapiens EPHA10 protein protein. 50 1e-05
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 50 1e-05
BC034417-1|AAH34417.1| 168|Homo sapiens YSK4 protein protein. 50 1e-05
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 50 1e-05
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 50 1e-05
AK131215-1|BAD18404.1| 543|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AJ872185-1|CAI43321.1| 1008|Homo sapiens Ephrin type-A receptor ... 50 1e-05
AC016725-3|AAY14999.1| 168|Homo sapiens unknown protein. 50 1e-05
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 50 1e-05
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 50 1e-05
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 50 1e-05
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 50 1e-05
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 50 1e-05
AK026727-1|BAB15538.1| 168|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein. 48 3e-05
X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein. 48 4e-05
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 48 4e-05
X54637-1|CAA38449.1| 1187|Homo sapiens protein ( Human tyk2 mRNA... 48 4e-05
L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kina... 48 4e-05
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 48 4e-05
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 48 4e-05
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 48 4e-05
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 48 4e-05
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 48 4e-05
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 48 4e-05
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 48 4e-05
AK000556-1|BAA91251.1| 293|Homo sapiens protein ( Homo sapiens ... 48 4e-05
AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase... 48 4e-05
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 48 4e-05
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 48 4e-05
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 48 4e-05
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 47 7e-05
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 47 7e-05
X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein. 47 7e-05
U63721-3|AAC13886.1| 633|Homo sapiens LIM-kinase protein. 47 7e-05
U63721-2|AAC13885.1| 647|Homo sapiens LIM-kinase protein. 47 7e-05
U62293-2|AAB17546.1| 633|Homo sapiens alternatively spliced LIM... 47 7e-05
U62293-1|AAB17545.1| 647|Homo sapiens LIM-kinase1 protein. 47 7e-05
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 47 7e-05
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 47 7e-05
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 47 7e-05
M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kina... 47 7e-05
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 47 7e-05
D26309-1|BAA05371.1| 647|Homo sapiens LIM kinase protein. 47 7e-05
BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase... 47 7e-05
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 47 7e-05
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 47 7e-05
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 47 7e-05
BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase... 47 7e-05
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 47 7e-05
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 47 7e-05
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 47 7e-05
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 47 7e-05
AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase... 47 7e-05
AC005057-3|AAS07438.1| 596|Homo sapiens unknown protein. 47 7e-05
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 47 7e-05
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 47 9e-05
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 47 9e-05
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 47 9e-05
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 47 9e-05
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 47 9e-05
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 47 9e-05
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 47 9e-05
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 47 9e-05
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 47 9e-05
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 47 9e-05
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 47 9e-05
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 47 9e-05
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 47 9e-05
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 47 9e-05
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 47 9e-05
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 47 9e-05
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 47 9e-05
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 47 9e-05
AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 47 9e-05
AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 47 9e-05
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 47 9e-05
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 47 9e-05
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 47 9e-05
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 47 9e-05
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 47 9e-05
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 47 9e-05
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 47 9e-05
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 47 9e-05
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 47 9e-05
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 46 1e-04
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 46 1e-04
X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein. 46 1e-04
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 46 1e-04
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 46 1e-04
M12724-1|AAA52762.1| 306|Homo sapiens FGR protein. 46 1e-04
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 46 1e-04
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 46 1e-04
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 46 1e-04
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 46 1e-04
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 46 1e-04
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 46 1e-04
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 46 1e-04
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 46 1e-04
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 46 1e-04
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 46 1e-04
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 46 1e-04
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 46 1e-04
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 46 1e-04
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 46 2e-04
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 46 2e-04
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 46 2e-04
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 46 2e-04
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 46 2e-04
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 46 2e-04
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 46 2e-04
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 46 2e-04
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 46 2e-04
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 46 2e-04
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 46 2e-04
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 46 2e-04
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 46 2e-04
BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein. 46 2e-04
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 46 2e-04
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 46 2e-04
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 46 2e-04
AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform pr... 46 2e-04
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 46 2e-04
AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform pr... 46 2e-04
AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform pr... 46 2e-04
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 46 2e-04
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 46 2e-04
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 46 2e-04
AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-depende... 46 2e-04
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 46 2e-04
AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-depende... 46 2e-04
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 46 2e-04
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 46 2e-04
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 46 2e-04
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 45 3e-04
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 45 3e-04
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 45 3e-04
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 45 3e-04
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 45 3e-04
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 45 3e-04
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 45 3e-04
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 45 3e-04
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 45 3e-04
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 45 3e-04
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 45 3e-04
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 45 3e-04
Z25426-1|CAA80913.1| 113|Homo sapiens protein-serine/threonine ... 45 4e-04
BX537852-1|CAD97860.1| 651|Homo sapiens hypothetical protein pr... 45 4e-04
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 45 4e-04
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 45 4e-04
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 45 4e-04
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 45 4e-04
AL023754-2|CAI19990.1| 245|Homo sapiens calcium/calmodulin-depe... 45 4e-04
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 45 4e-04
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 45 4e-04
AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens ... 45 4e-04
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 45 4e-04
AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant MYO... 45 4e-04
AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant MYO... 45 4e-04
AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant MYO... 45 4e-04
AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant MYO... 45 4e-04
AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant MYO... 45 4e-04
AF369908-1|AAL57233.1| 1278|Homo sapiens myosin IIIB protein. 45 4e-04
AC114794-1|AAY24159.1| 249|Homo sapiens unknown protein. 45 4e-04
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 44 5e-04
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 44 5e-04
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 44 5e-04
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 44 5e-04
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 44 5e-04
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 44 5e-04
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 44 5e-04
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 44 5e-04
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 44 5e-04
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 44 5e-04
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 44 5e-04
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 44 5e-04
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 44 5e-04
AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protei... 44 5e-04
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 44 5e-04
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 44 5e-04
AB209829-1|BAD93066.1| 214|Homo sapiens cyclin-dependent kinase... 44 5e-04
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 44 5e-04
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 44 5e-04
X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein ... 44 6e-04
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 44 6e-04
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 44 6e-04
AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase... 44 6e-04
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 44 6e-04
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 44 6e-04
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 44 6e-04
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 44 6e-04
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 44 6e-04
Z25422-1|CAA80909.1| 108|Homo sapiens protein-serine/threonine ... 44 8e-04
Y12337-1|CAA73006.1| 289|Homo sapiens myotonic dystrophy protei... 44 8e-04
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 44 8e-04
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 44 8e-04
AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy kina... 44 8e-04
AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein. 44 8e-04
AC005793-1|AAC62830.1| 593|Homo sapiens KIAA0561 protein [AA 1-... 44 8e-04
AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein. 44 8e-04
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 43 0.001
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 43 0.001
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 43 0.001
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 43 0.001
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 43 0.001
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 43 0.001
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 43 0.001
>AY290821-1|AAP42280.1| 348|Homo sapiens LYK5 protein protein.
Length = 348
Score = 166 bits (403), Expect = 9e-41
Identities = 85/212 (40%), Positives = 131/212 (61%), Gaps = 1/212 (0%)
Frame = +1
Query: 166 ILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQ 342
++ P+ Y+L ++I + + V A YKP V ++R ++ E T +Q
Sbjct: 21 VMSSFLPEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQG 80
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
++ K +H NI+PY A+F+ EL+VV+ M++GS +D++ +F +G++ELA A +L+
Sbjct: 81 ELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQ 140
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
VL+AL Y+H Y+HRSV+ASH+LI +G LSGLR+ SM+ GQRQR +H
Sbjct: 141 GVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVH--DFPK 198
Query: 703 HDNANLMWLSPEVLEQNLKGYDERSDITPSGV 798
+ L WLSPEVL+QNL+GYD +SDI G+
Sbjct: 199 YSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGI 230
>AK075005-1|BAC11349.1| 348|Homo sapiens protein ( Homo sapiens
cDNA FLJ90524 fis, clone NT2RP4000962, weakly similar to
SPORULATION-SPECIFIC PROTEIN 1 (EC 2.7.1.-). ).
Length = 348
Score = 166 bits (403), Expect = 9e-41
Identities = 85/212 (40%), Positives = 131/212 (61%), Gaps = 1/212 (0%)
Frame = +1
Query: 166 ILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQ 342
++ P+ Y+L ++I + + V A YKP V ++R ++ E T +Q
Sbjct: 21 VMSSFLPEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQG 80
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
++ K +H NI+PY A+F+ EL+VV+ M++GS +D++ +F +G++ELA A +L+
Sbjct: 81 ELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQ 140
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
VL+AL Y+H Y+HRSV+ASH+LI +G LSGLR+ SM+ GQRQR +H
Sbjct: 141 GVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVH--DFPK 198
Query: 703 HDNANLMWLSPEVLEQNLKGYDERSDITPSGV 798
+ L WLSPEVL+QNL+GYD +SDI G+
Sbjct: 199 YSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGI 230
>AK074771-1|BAC11197.1| 394|Homo sapiens protein ( Homo sapiens
cDNA FLJ90290 fis, clone NT2RP1001020, weakly similar to
SERINE/THREONINE-PROTEIN KINASE PAK-BETA (EC 2.7.1.-).
).
Length = 394
Score = 166 bits (403), Expect = 9e-41
Identities = 85/212 (40%), Positives = 131/212 (61%), Gaps = 1/212 (0%)
Frame = +1
Query: 166 ILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQ 342
++ P+ Y+L ++I + + V A YKP V ++R ++ E T +Q
Sbjct: 21 VMSSFLPEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQG 80
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
++ K +H NI+PY A+F+ EL+VV+ M++GS +D++ +F +G++ELA A +L+
Sbjct: 81 ELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQ 140
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
VL+AL Y+H Y+HRSV+ASH+LI +G LSGLR+ SM+ GQRQR +H
Sbjct: 141 GVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVH--DFPK 198
Query: 703 HDNANLMWLSPEVLEQNLKGYDERSDITPSGV 798
+ L WLSPEVL+QNL+GYD +SDI G+
Sbjct: 199 YSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGI 230
>AF308302-1|AAG48269.1| 431|Homo sapiens serologically defined
breast cancer antigen NY-BR-96 protein.
Length = 431
Score = 166 bits (403), Expect = 9e-41
Identities = 85/212 (40%), Positives = 131/212 (61%), Gaps = 1/212 (0%)
Frame = +1
Query: 166 ILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQ 342
++ P+ Y+L ++I + + V A YKP V ++R ++ E T +Q
Sbjct: 58 VMSSFLPEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQG 117
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
++ K +H NI+PY A+F+ EL+VV+ M++GS +D++ +F +G++ELA A +L+
Sbjct: 118 ELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQ 177
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
VL+AL Y+H Y+HRSV+ASH+LI +G LSGLR+ SM+ GQRQR +H
Sbjct: 178 GVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVH--DFPK 235
Query: 703 HDNANLMWLSPEVLEQNLKGYDERSDITPSGV 798
+ L WLSPEVL+QNL+GYD +SDI G+
Sbjct: 236 YSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGI 267
>BC043641-1|AAH43641.1| 234|Homo sapiens LYK5 protein protein.
Length = 234
Score = 155 bits (375), Expect = 2e-37
Identities = 83/206 (40%), Positives = 126/206 (61%), Gaps = 1/206 (0%)
Frame = +1
Query: 184 PDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRK 360
P+ Y+L ++I + + V A YKP V ++R ++ E T +Q ++ K
Sbjct: 6 PEGGCYELLTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQGELHVSK 65
Query: 361 ELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQAL 540
+H NI+PY A+F+ EL+VV+ M++GS +D++ +F +G++ELA A +L+ VL+AL
Sbjct: 66 LFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQGVLKAL 125
Query: 541 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANL 720
Y+H Y+HRSV+ASH+LI +G LSGLR+ SM+ GQRQR +H + L
Sbjct: 126 DYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVH--DFPKYSVKVL 183
Query: 721 MWLSPEVLEQNLKGYDERSDITPSGV 798
WLSPEVL+Q GYD +SDI G+
Sbjct: 184 PWLSPEVLQQ---GYDAKSDIYSVGI 206
>BC090871-1|AAH90871.1| 377|Homo sapiens ALS2CR2 protein protein.
Length = 377
Score = 131 bits (316), Expect = 3e-30
Identities = 74/209 (35%), Positives = 113/209 (54%), Gaps = 1/209 (0%)
Frame = +1
Query: 175 MLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVL 351
+ S +++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 50 LCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVI 109
Query: 352 TRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVL 531
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L +
Sbjct: 110 LSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAV 169
Query: 532 QALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDN 711
+ L YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++
Sbjct: 170 RGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVY--DFPQFST 227
Query: 712 ANLMWLSPEVLEQNLKGYDERSDITPSGV 798
+ WLSPE+L Q+L GY+ +SDI G+
Sbjct: 228 SVQPWLSPELLRQDLHGYNVKSDIYSVGI 256
>BC008302-1|AAH08302.1| 418|Homo sapiens amyotrophic lateral
sclerosis 2 (juvenile) chromosome region, candidate 2
protein.
Length = 418
Score = 131 bits (316), Expect = 3e-30
Identities = 74/209 (35%), Positives = 113/209 (54%), Gaps = 1/209 (0%)
Frame = +1
Query: 175 MLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVL 351
+ S +++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 50 LCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVI 109
Query: 352 TRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVL 531
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L +
Sbjct: 110 LSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAV 169
Query: 532 QALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDN 711
+ L YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++
Sbjct: 170 RGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVY--DFPQFST 227
Query: 712 ANLMWLSPEVLEQNLKGYDERSDITPSGV 798
+ WLSPE+L Q+L GY+ +SDI G+
Sbjct: 228 SVQPWLSPELLRQDLHGYNVKSDIYSVGI 256
>AY093697-1|AAM19143.1| 418|Homo sapiens ILP-interacting protein
ILPIPA protein.
Length = 418
Score = 131 bits (316), Expect = 3e-30
Identities = 74/209 (35%), Positives = 113/209 (54%), Gaps = 1/209 (0%)
Frame = +1
Query: 175 MLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVL 351
+ S +++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 50 LCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVI 109
Query: 352 TRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVL 531
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L +
Sbjct: 110 LSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAV 169
Query: 532 QALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDN 711
+ L YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++
Sbjct: 170 RGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVY--DFPQFST 227
Query: 712 ANLMWLSPEVLEQNLKGYDERSDITPSGV 798
+ WLSPE+L Q+L GY+ +SDI G+
Sbjct: 228 SVQPWLSPELLRQDLHGYNVKSDIYSVGI 256
>AK027637-1|BAB55254.1| 418|Homo sapiens protein ( Homo sapiens
cDNA FLJ14731 fis, clone NT2RP3001938, weakly similar to
SPORULATION-SPECIFIC PROTEIN 1 (EC 2.7.1.-). ).
Length = 418
Score = 131 bits (316), Expect = 3e-30
Identities = 74/209 (35%), Positives = 113/209 (54%), Gaps = 1/209 (0%)
Frame = +1
Query: 175 MLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVL 351
+ S +++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 50 LCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVI 109
Query: 352 TRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVL 531
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L +
Sbjct: 110 LSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAV 169
Query: 532 QALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDN 711
+ L YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++
Sbjct: 170 RGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVY--DFPQFST 227
Query: 712 ANLMWLSPEVLEQNLKGYDERSDITPSGV 798
+ WLSPE+L Q+L GY+ +SDI G+
Sbjct: 228 SVQPWLSPELLRQDLHGYNVKSDIYSVGI 256
>AC007282-3|AAY14692.1| 418|Homo sapiens unknown protein.
Length = 418
Score = 131 bits (316), Expect = 3e-30
Identities = 74/209 (35%), Positives = 113/209 (54%), Gaps = 1/209 (0%)
Frame = +1
Query: 175 MLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVL 351
+ S +++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 50 LCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVI 109
Query: 352 TRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVL 531
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L +
Sbjct: 110 LSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAV 169
Query: 532 QALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDN 711
+ L YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++
Sbjct: 170 RGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVY--DFPQFST 227
Query: 712 ANLMWLSPEVLEQNLKGYDERSDITPSGV 798
+ WLSPE+L Q+L GY+ +SDI G+
Sbjct: 228 SVQPWLSPELLRQDLHGYNVKSDIYSVGI 256
>AB038950-1|BAB32500.1| 418|Homo sapiens amyotrophic lateral
sclerosis 2 protein.
Length = 418
Score = 131 bits (316), Expect = 3e-30
Identities = 74/209 (35%), Positives = 113/209 (54%), Gaps = 1/209 (0%)
Frame = +1
Query: 175 MLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVL 351
+ S +++ Y+L I D V+ A + P T V IK ++ +E+ +Q+ V+
Sbjct: 50 LCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVI 109
Query: 352 TRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVL 531
H NI Y F G L+V+SP M++GS +L YFPEG+SE +L +
Sbjct: 110 LSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAV 169
Query: 532 QALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDN 711
+ L YLH+ IHRS++ASH+LI +G+ LSGL S++ GQR R ++
Sbjct: 170 RGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVY--DFPQFST 227
Query: 712 ANLMWLSPEVLEQNLKGYDERSDITPSGV 798
+ WLSPE+L Q+L GY+ +SDI G+
Sbjct: 228 SVQPWLSPELLRQDLHGYNVKSDIYSVGI 256
>DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 109 bits (261), Expect = 2e-23
Identities = 68/208 (32%), Positives = 110/208 (52%), Gaps = 6/208 (2%)
Frame = +1
Query: 193 NDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHH 372
+DY+L +I S AVV +A P KVAIKR +++ + + +++ + HH
Sbjct: 15 DDYELQEVIG--SGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHH 72
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQ 534
NI+ Y SFV EL++V L+S GS DI+ +G + E A +LR+VL+
Sbjct: 73 PNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLE 132
Query: 535 ALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNA 714
L+YLHK IHR V+A ++L+G +G +++ +A + G R
Sbjct: 133 GLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRN----KVRKTFVG 188
Query: 715 NLMWLSPEVLEQNLKGYDERSDITPSGV 798
W++PEV+EQ ++GYD ++DI G+
Sbjct: 189 TPCWMAPEVMEQ-VRGYDFKADIWSFGI 215
>BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 109 bits (261), Expect = 2e-23
Identities = 68/208 (32%), Positives = 110/208 (52%), Gaps = 6/208 (2%)
Frame = +1
Query: 193 NDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHH 372
+DY+L +I S AVV +A P KVAIKR +++ + + +++ + HH
Sbjct: 15 DDYELQEVIG--SGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHH 72
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQ 534
NI+ Y SFV EL++V L+S GS DI+ +G + E A +LR+VL+
Sbjct: 73 PNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLE 132
Query: 535 ALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNA 714
L+YLHK IHR V+A ++L+G +G +++ +A + G R
Sbjct: 133 GLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRN----KVRKTFVG 188
Query: 715 NLMWLSPEVLEQNLKGYDERSDITPSGV 798
W++PEV+EQ ++GYD ++DI G+
Sbjct: 189 TPCWMAPEVMEQ-VRGYDFKADIWSFGI 215
>AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 109 bits (261), Expect = 2e-23
Identities = 68/208 (32%), Positives = 110/208 (52%), Gaps = 6/208 (2%)
Frame = +1
Query: 193 NDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHH 372
+DY+L +I S AVV +A P KVAIKR +++ + + +++ + HH
Sbjct: 15 DDYELQEVIG--SGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHH 72
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQ 534
NI+ Y SFV EL++V L+S GS DI+ +G + E A +LR+VL+
Sbjct: 73 PNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLE 132
Query: 535 ALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNA 714
L+YLHK IHR V+A ++L+G +G +++ +A + G R
Sbjct: 133 GLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRN----KVRKTFVG 188
Query: 715 NLMWLSPEVLEQNLKGYDERSDITPSGV 798
W++PEV+EQ ++GYD ++DI G+
Sbjct: 189 TPCWMAPEVMEQ-VRGYDFKADIWSFGI 215
>AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase SPAK
protein.
Length = 547
Score = 98.3 bits (234), Expect = 3e-20
Identities = 62/206 (30%), Positives = 107/206 (51%), Gaps = 6/206 (2%)
Frame = +1
Query: 199 YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHAN 378
Y+L +I S AVV +AL KP +VAIKR +++ + + +++ + H N
Sbjct: 65 YELQEVIG--SGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN 122
Query: 379 ILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQAL 540
++ Y SFV EL++V L+S GS DI+ G + E A +L++VL+ L
Sbjct: 123 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL 182
Query: 541 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANL 720
YLH+ IHR ++A ++L+G +G +++ +A + G R
Sbjct: 183 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRN----KVRKTFVGTP 238
Query: 721 MWLSPEVLEQNLKGYDERSDITPSGV 798
W++PEV+EQ ++GYD ++D+ G+
Sbjct: 239 CWMAPEVMEQ-VRGYDFKADMWSFGI 263
>AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein.
Length = 363
Score = 98.3 bits (234), Expect = 3e-20
Identities = 62/206 (30%), Positives = 107/206 (51%), Gaps = 6/206 (2%)
Frame = +1
Query: 199 YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHAN 378
Y+L +I S AVV +AL KP +VAIKR +++ + + +++ + H N
Sbjct: 63 YELQEVIG--SGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN 120
Query: 379 ILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQAL 540
++ Y SFV EL++V L+S GS DI+ G + E A +L++VL+ L
Sbjct: 121 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL 180
Query: 541 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANL 720
YLH+ IHR ++A ++L+G +G +++ +A + G R
Sbjct: 181 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRN----KVRKTFVGTP 236
Query: 721 MWLSPEVLEQNLKGYDERSDITPSGV 798
W++PEV+EQ ++GYD ++D+ G+
Sbjct: 237 CWMAPEVMEQ-VRGYDFKADMWSFGI 261
>AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kinase
protein.
Length = 547
Score = 96.7 bits (230), Expect = 9e-20
Identities = 61/206 (29%), Positives = 106/206 (51%), Gaps = 6/206 (2%)
Frame = +1
Query: 199 YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHAN 378
Y+L +I S AVV +AL KP +VAIKR +++ + + +++ + H N
Sbjct: 65 YELQEVIG--SGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN 122
Query: 379 ILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQAL 540
++ Y SFV EL++V L+S GS DI+ G + E A + ++VL+ L
Sbjct: 123 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATIFKEVLEGL 182
Query: 541 QYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANL 720
YLH+ IHR ++A ++L+G +G +++ +A + G R
Sbjct: 183 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRN----KVRKTFVGTP 238
Query: 721 MWLSPEVLEQNLKGYDERSDITPSGV 798
W++PEV+EQ ++GYD ++D+ G+
Sbjct: 239 CWMAPEVMEQ-VRGYDFKADMWSFGI 263
>AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein.
Length = 467
Score = 88.6 bits (210), Expect = 2e-17
Identities = 52/158 (32%), Positives = 84/158 (53%), Gaps = 6/158 (3%)
Frame = +1
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG------ISELA 504
++ + HH NI+ Y SFV EL++V L+S GS DI+ +G + E
Sbjct: 3 EIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEST 62
Query: 505 CAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLH 684
A +LR+VL+ L+YLHK IHR V+A ++L+G +G +++ +A + G R
Sbjct: 63 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRN-- 120
Query: 685 LLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGV 798
W++PEV+EQ ++GYD ++DI G+
Sbjct: 121 --KVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGI 155
>AY629298-1|AAT65492.1| 476|Homo sapiens small intestine SPAK-like
kinase protein.
Length = 476
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/179 (29%), Positives = 90/179 (50%), Gaps = 6/179 (3%)
Frame = +1
Query: 229 SDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVH 408
S AVV +AL KP +VAIKR +++ + + +++ + H N++ Y SFV
Sbjct: 22 SGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVV 81
Query: 409 GRELYVVSPLMSFGSCRDILDRYFPEG------ISELACAIVLRDVLQALQYLHKQLYIH 570
EL++V L+S GS DI+ G + E A +L++VL+ L YLH+ IH
Sbjct: 82 KDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIH 141
Query: 571 RSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLE 747
R ++A ++L+G +G +++ +A + G R W++PEV+E
Sbjct: 142 RDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRN----KVRKTFVGTPCWMAPEVME 196
>U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor
kinase protein.
Length = 833
Score = 81.0 bits (191), Expect = 5e-15
Identities = 58/185 (31%), Positives = 92/185 (49%), Gaps = 1/185 (0%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ A K + VA+K ++ + +TL Q+++L K HANI+ Y S++ ++L++
Sbjct: 31 VFKARDKVSGDLVALKMVKMEPDDDVSTL-QKEILILKTCRHANIVAYHGSYLWLQKLWI 89
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
GS +DI +SEL + V R+VLQ L YLH Q IHR ++ +++LI
Sbjct: 90 CMEFCGAGSLQDIYQ--VTGSLSELQISYVCREVLQGLAYLHSQKKIHRDIKGANILIND 147
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLK-GYDERSDI 783
G RL+ S + R+L + W++PEV LK GY+E DI
Sbjct: 148 AGEVRLADF--GISAQIGATLARRLSFI-------GTPYWMAPEVAAVALKGGYNELCDI 198
Query: 784 TPSGV 798
G+
Sbjct: 199 WSLGI 203
>U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kinase
protein.
Length = 525
Score = 78.2 bits (184), Expect = 3e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G V++A +VAIK+ + + + K L
Sbjct: 235 KLRTIVSIGDPK-KKYTRYEKIGQGASG--TVFTATDVALGQEVAIKQINLQK-QPKKEL 290
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L KEL + NI+ +L S++ G EL+VV ++ GS D++ + E A
Sbjct: 291 IINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTE--TACMDEAQIAA 348
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL++LH IHR +++ +VL+G G +L+ A + Q K +
Sbjct: 349 VCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQIT---PEQSKRSTMV 405
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 406 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 433
>U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kinase
protein.
Length = 545
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/216 (28%), Positives = 108/216 (50%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+A+ +VAIK+ + + + K L
Sbjct: 256 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTAMDVATGQEVAIKQMNLQQ-QPKKEL 311
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 312 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 368
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL++LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 369 VCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 425
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 426 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 453
>BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activated
kinase 1 (STE20 homolog, yeast) protein.
Length = 545
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/216 (28%), Positives = 108/216 (50%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+A+ +VAIK+ + + + K L
Sbjct: 256 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTAMDVATGQEVAIKQMNLQQ-QPKKEL 311
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 312 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 368
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL++LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 369 VCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 425
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 426 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 453
>BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2
protein.
Length = 524
Score = 77.8 bits (183), Expect = 4e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G V++A +VAIK+ + + + K L
Sbjct: 235 KLRTIVSIGDPK-KKYTRYEKIGQRASG--TVFTATDVALGQEVAIKQINLQK-QPKKEL 290
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L KEL + NI+ +L S++ G EL+VV ++ GS D++ + E A
Sbjct: 291 IINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETC---MDEAQIAA 347
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL++LH IHR +++ +VL+G G +L+ A + Q K +
Sbjct: 348 VCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQIT---PEQSKRSTMV 404
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 405 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 432
>AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B
protein.
Length = 553
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/216 (28%), Positives = 108/216 (50%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+A+ +VAIK+ + + + K L
Sbjct: 256 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTAMDVATGQEVAIKQMNLQQ-QPKKEL 311
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 312 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 368
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL++LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 369 VCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 425
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 426 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 453
>AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+AL +VAIK+ + + + K L
Sbjct: 254 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTALDIATGQEVAIKQMNLQQ-QPKKEL 309
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 310 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 366
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL +LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 367 VCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 423
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 424 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 451
>AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+AL +VAIK+ + + + K L
Sbjct: 269 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTALDIATGQEVAIKQMNLQQ-QPKKEL 324
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 325 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 381
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL +LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 382 VCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 438
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 439 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 466
>AL117326-3|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+AL +VAIK+ + + + K L
Sbjct: 254 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTALDIATGQEVAIKQMNLQQ-QPKKEL 309
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 310 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 366
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL +LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 367 VCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 423
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 424 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 451
>AL117326-2|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+AL +VAIK+ + + + K L
Sbjct: 269 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTALDIATGQEVAIKQMNLQQ-QPKKEL 324
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 325 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 381
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL +LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 382 VCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 438
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 439 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 466
>AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+AL +VAIK+ + + + K L
Sbjct: 254 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTALDIATGQEVAIKQMNLQQ-QPKKEL 309
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 310 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 366
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL +LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 367 VCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 423
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 424 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 451
>AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+AL +VAIK+ + + + K L
Sbjct: 269 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTALDIATGQEVAIKQMNLQQ-QPKKEL 324
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 325 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 381
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL +LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 382 VCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 438
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 439 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 466
>AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3
protein.
Length = 544
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+AL +VAIK+ + + + K L
Sbjct: 254 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTALDIATGQEVAIKQMNLQQ-QPKKEL 309
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 310 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 366
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL +LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 367 VCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 423
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 424 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 451
>AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3
protein.
Length = 544
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+AL +VAIK+ + + + K L
Sbjct: 254 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTALDIATGQEVAIKQMNLQQ-QPKKEL 309
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 310 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 366
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL +LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 367 VCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 423
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 424 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 451
>AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3
protein.
Length = 559
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/216 (29%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+AL +VAIK+ + + + K L
Sbjct: 269 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTALDIATGQEVAIKQMNLQQ-QPKKEL 324
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 325 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 381
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL +LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 382 VCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 438
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 439 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 466
>CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein.
Length = 431
Score = 76.2 bits (179), Expect = 1e-13
Identities = 46/184 (25%), Positives = 92/184 (50%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
+G +L+ + A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 HGEVKLADI-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIKQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein.
Length = 545
Score = 75.8 bits (178), Expect = 2e-13
Identities = 62/216 (28%), Positives = 107/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G VY+A+ +VAIK+ + + + K L
Sbjct: 256 KLRSIVSVGDPK-KKYTRFEKIGQGASG--TVYTAMDVATGQEVAIKQMNLQQ-QPKKEL 311
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L +E + NI+ YL S++ G EL+VV ++ GS D++ + E A
Sbjct: 312 IINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC---MDEGQIAA 368
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL+ LH IHR +++ ++L+G +G +L+ A + Q K +
Sbjct: 369 VCRECLQALESLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT---PEQSKRSTMV 425
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 426 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 453
>BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein.
Length = 873
Score = 75.8 bits (178), Expect = 2e-13
Identities = 52/192 (27%), Positives = 94/192 (48%), Gaps = 5/192 (2%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G+ Y +YK N AIK ++ G++ A ++QQ+++ K+ H NI+ Y S++
Sbjct: 23 GSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA-VVQQEIIMMKDCKHPNIVAYFGSYL 81
Query: 406 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 585
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 82 RRDKLWICMEFCGGGSLQDIYHVTGP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKG 139
Query: 586 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLK-G 762
+++L+ NG +L+ +A + +++ W++PEV K G
Sbjct: 140 ANILLTDNGHVKLADFGVSAQITATIAKRKSF---------IGTPYWMAPEVAAVERKGG 190
Query: 763 YDERSDITPSGV 798
Y++ D+ G+
Sbjct: 191 YNQLCDLWAVGI 202
>AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein.
Length = 873
Score = 75.8 bits (178), Expect = 2e-13
Identities = 52/192 (27%), Positives = 94/192 (48%), Gaps = 5/192 (2%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G+ Y +YK N AIK ++ G++ A ++QQ+++ K+ H NI+ Y S++
Sbjct: 23 GSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA-VVQQEIIMMKDCKHPNIVAYFGSYL 81
Query: 406 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 585
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 82 RRDKLWICMEFCGGGSLQDIYHVTGP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKG 139
Query: 586 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLK-G 762
+++L+ NG +L+ +A + +++ W++PEV K G
Sbjct: 140 ANILLTDNGHVKLADFGVSAQITATIAKRKSF---------IGTPYWMAPEVAAVERKGG 190
Query: 763 YDERSDITPSGV 798
Y++ D+ G+
Sbjct: 191 YNQLCDLWAVGI 202
>AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein.
Length = 894
Score = 75.8 bits (178), Expect = 2e-13
Identities = 52/192 (27%), Positives = 94/192 (48%), Gaps = 5/192 (2%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G+ Y +YK N AIK ++ G++ A ++QQ+++ K+ H NI+ Y S++
Sbjct: 23 GSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA-VVQQEIIMMKDCKHPNIVAYFGSYL 81
Query: 406 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 585
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 82 RRDKLWICMEFCGGGSLQDIYHVTGP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKG 139
Query: 586 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLK-G 762
+++L+ NG +L+ +A + +++ W++PEV K G
Sbjct: 140 ANILLTDNGHVKLADFGVSAQITATIAKRKSF---------IGTPYWMAPEVAAVERKGG 190
Query: 763 YDERSDITPSGV 798
Y++ D+ G+
Sbjct: 191 YNQLCDLWAVGI 202
>AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase
related protein kinase protein.
Length = 884
Score = 75.8 bits (178), Expect = 2e-13
Identities = 52/192 (27%), Positives = 94/192 (48%), Gaps = 5/192 (2%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G+ Y +YK N AIK ++ G++ A ++QQ+++ K+ H NI+ Y S++
Sbjct: 13 GSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA-VVQQEIIMMKDCKHPNIVAYFGSYL 71
Query: 406 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 585
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 72 RRDKLWICMEFCGGGSLQDIYHVTGP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKG 129
Query: 586 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLK-G 762
+++L+ NG +L+ +A + +++ W++PEV K G
Sbjct: 130 ANILLTDNGHVKLADFGVSAQITATIAKRKSF---------IGTPYWMAPEVAAVERKGG 180
Query: 763 YDERSDITPSGV 798
Y++ D+ G+
Sbjct: 181 YNQLCDLWAVGI 192
>AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein.
Length = 712
Score = 75.8 bits (178), Expect = 2e-13
Identities = 52/192 (27%), Positives = 94/192 (48%), Gaps = 5/192 (2%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G+ Y +YK N AIK ++ G++ A ++QQ+++ K+ H NI+ Y S++
Sbjct: 23 GSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA-VVQQEIIMMKDCKHPNIVAYFGSYL 81
Query: 406 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 585
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 82 RRDKLWICMEFCGGGSLQDIYHVTGP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKG 139
Query: 586 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLK-G 762
+++L+ NG +L+ +A + +++ W++PEV K G
Sbjct: 140 ANILLTDNGHVKLADFGVSAQITATIAKRKSF---------IGTPYWMAPEVAAVERKGG 190
Query: 763 YDERSDITPSGV 798
Y++ D+ G+
Sbjct: 191 YNQLCDLWAVGI 202
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 46/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
+G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIKQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 46/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
+G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIKQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 46/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
+G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIKQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 46/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
+G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIKQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 75.4 bits (177), Expect = 2e-13
Identities = 46/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 50 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 109
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 110 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 166
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
+G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 167 HGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIKQS--AYDSKADIW 215
Query: 787 PSGV 798
G+
Sbjct: 216 SLGI 219
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 46/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
+G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIKQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 75.4 bits (177), Expect = 2e-13
Identities = 46/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 50 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 109
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 110 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 166
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
+G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 167 HGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIKQS--AYDSKADIW 215
Query: 787 PSGV 798
G+
Sbjct: 216 SLGI 219
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 75.4 bits (177), Expect = 2e-13
Identities = 46/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 50 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 109
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 110 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 166
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
+G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 167 HGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIKQS--AYDSKADIW 215
Query: 787 PSGV 798
G+
Sbjct: 216 SLGI 219
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 75.4 bits (177), Expect = 2e-13
Identities = 46/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + Y S++ +L++
Sbjct: 38 VFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L+ P + E A +LR++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
+G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 HGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIKQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein.
Length = 493
Score = 74.9 bits (176), Expect = 3e-13
Identities = 63/216 (29%), Positives = 106/216 (49%)
Frame = +1
Query: 154 KLRFILEMLSPDINDYQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATL 333
KLR I+ + P Y I + + G V++A +VAIK+ + + + K L
Sbjct: 204 KLRTIVSIGDPK-KKYTRYEKIGQGASG--TVFTATDVALGQEVAIKQINLQK-QPKKEL 259
Query: 334 IQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAI 513
I ++L KEL + NI+ +L S++ G EL+VV M + + R + D + E A
Sbjct: 260 IINEILVMKELKNPNIVNFLDSYLVGDELFVV---MEYLAGRSLTDVVTETCMDEAQIAA 316
Query: 514 VLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLX 693
V R+ LQAL++LH IHR +++ +VL+G G +L+ A + Q K +
Sbjct: 317 VCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQIT---PEQSKRSTMV 373
Query: 694 XXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ W++PEV+ + K Y + DI G++
Sbjct: 374 GTPY------WMAPEVVTR--KAYGPKVDIWSLGIM 401
>X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein.
Length = 426
Score = 74.5 bits (175), Expect = 4e-13
Identities = 53/199 (26%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Frame = +1
Query: 214 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 381
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 382 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 561
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 562 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++A++VL+ G +L+ A + Q +R + W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEV 186
Query: 742 LEQNLKGYDERSDITPSGV 798
++Q+ YD ++DI G+
Sbjct: 187 IKQS--AYDFKADIWSLGI 203
>U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein.
Length = 846
Score = 74.5 bits (175), Expect = 4e-13
Identities = 55/193 (28%), Positives = 95/193 (49%), Gaps = 6/193 (3%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G+ Y +YK N A+K ++ G + +LIQQ++ KE H NI+ Y S++
Sbjct: 27 GSGTYGDVYKARNVHTGELAAVKIIKLEPGDD-FSLIQQEIFMVKECKHCNIVAYFGSYL 85
Query: 406 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 585
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 86 SREKLWICMEYCGGGSLQDIYHVTGP--LSELQIAYVCRETLQGLAYLHTKGKMHRDIKG 143
Query: 586 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEV--LEQNLK 759
+++L+ +G +L+ AA + +++ W++PEV +E+N
Sbjct: 144 ANILLTDHGDVKLADFGVAAKITATIAKRKSF---------IGTPYWMAPEVAAVEKN-G 193
Query: 760 GYDERSDITPSGV 798
GY++ DI G+
Sbjct: 194 GYNQLCDIWAVGI 206
>D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein.
Length = 426
Score = 74.5 bits (175), Expect = 4e-13
Identities = 53/199 (26%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Frame = +1
Query: 214 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 381
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 382 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 561
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 562 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++A++VL+ G +L+ A + Q +R + W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEV 186
Query: 742 LEQNLKGYDERSDITPSGV 798
++Q+ YD ++DI G+
Sbjct: 187 IKQS--AYDFKADIWSLGI 203
>DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 74.5 bits (175), Expect = 4e-13
Identities = 53/199 (26%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Frame = +1
Query: 214 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 381
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 382 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 561
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 562 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++A++VL+ G +L+ A + Q +R + W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEV 186
Query: 742 LEQNLKGYDERSDITPSGV 798
++Q+ YD ++DI G+
Sbjct: 187 IKQS--AYDFKADIWSLGI 203
>BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 74.5 bits (175), Expect = 4e-13
Identities = 53/199 (26%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Frame = +1
Query: 214 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 381
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 382 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 561
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 562 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++A++VL+ G +L+ A + Q +R + W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEV 186
Query: 742 LEQNLKGYDERSDITPSGV 798
++Q+ YD ++DI G+
Sbjct: 187 IKQS--AYDFKADIWSLGI 203
>BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein.
Length = 426
Score = 74.5 bits (175), Expect = 4e-13
Identities = 53/199 (26%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Frame = +1
Query: 214 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 381
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 382 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 561
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 562 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++A++VL+ G +L+ A + Q +R + W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEV 186
Query: 742 LEQNLKGYDERSDITPSGV 798
++Q+ YD ++DI G+
Sbjct: 187 IKQS--AYDFKADIWSLGI 203
>BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated protein
kinase kinase kinase kinase 5 protein.
Length = 846
Score = 74.5 bits (175), Expect = 4e-13
Identities = 55/193 (28%), Positives = 95/193 (49%), Gaps = 6/193 (3%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G+ Y +YK N A+K ++ G + +LIQQ++ KE H NI+ Y S++
Sbjct: 27 GSGTYGDVYKARNVHTGELAAVKIIKLEPGDD-FSLIQQEIFMVKECKHCNIVAYFGSYL 85
Query: 406 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 585
+L++ GS +DI P +SEL A V R+ LQ L YLH + +HR ++
Sbjct: 86 SREKLWICMEYCGGGSLQDIYHVTGP--LSELQIAYVCRETLQGLAYLHTKGKMHRDIKG 143
Query: 586 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEV--LEQNLK 759
+++L+ +G +L+ AA + +++ W++PEV +E+N
Sbjct: 144 ANILLTDHGDVKLADFGVAAKITATIAKRKSF---------IGTPYWMAPEVAAVEKN-G 193
Query: 760 GYDERSDITPSGV 798
GY++ DI G+
Sbjct: 194 GYNQLCDIWAVGI 206
>BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein.
Length = 426
Score = 74.5 bits (175), Expect = 4e-13
Identities = 53/199 (26%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Frame = +1
Query: 214 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 381
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 382 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 561
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 562 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++A++VL+ G +L+ A + Q +R + W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEV 186
Query: 742 LEQNLKGYDERSDITPSGV 798
++Q+ YD ++DI G+
Sbjct: 187 IKQS--AYDFKADIWSLGI 203
>BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 74.5 bits (175), Expect = 4e-13
Identities = 53/199 (26%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Frame = +1
Query: 214 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 381
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 382 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 561
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 562 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++A++VL+ G +L+ A + Q +R + W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEV 186
Query: 742 LEQNLKGYDERSDITPSGV 798
++Q+ YD ++DI G+
Sbjct: 187 IKQS--AYDFKADIWSLGI 203
>AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein.
Length = 426
Score = 74.5 bits (175), Expect = 4e-13
Identities = 53/199 (26%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Frame = +1
Query: 214 IITECSDGGAVVYSALYK--PNNTK--VAIKRYFVDRGKEKATLIQQDVLTRKELHHANI 381
+ T+ G + +YK N+TK VAIK ++ +++ IQQ++ + I
Sbjct: 19 LFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYI 78
Query: 382 LPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQL 561
Y S++ +L+++ + GS D+L P + E A +LR++L+ L YLH +
Sbjct: 79 TRYFGSYLKSTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHSER 135
Query: 562 YIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++A++VL+ G +L+ A + Q +R + W++PEV
Sbjct: 136 KIHRDIKAANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEV 186
Query: 742 LEQNLKGYDERSDITPSGV 798
++Q+ YD ++DI G+
Sbjct: 187 IKQS--AYDFKADIWSLGI 203
>AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2
variant protein.
Length = 279
Score = 74.1 bits (174), Expect = 5e-13
Identities = 54/185 (29%), Positives = 94/185 (50%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V++A KVAIK+ + + + K LI ++L KEL + NI+ +L S++ G EL+V
Sbjct: 21 VFTATDVALGQKVAIKQINLQK-QPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFV 79
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V ++ GS D++ + E A V R+ LQAL++LH IHR +++ VL+G
Sbjct: 80 VVEYLARGSLTDVVTETC---MDEAQIAAVCRESLQALEFLHANQVIHRDIKSDSVLLGM 136
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G +L+ A + Q K + + W++PEV+ + K Y + ++
Sbjct: 137 EGSVKLTDFGFCAQIT---PEQSKRSTVIRTPY------WMAPEVVTR--KAYGPKVNVW 185
Query: 787 PSGVL 801
G++
Sbjct: 186 SLGIM 190
>BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related
kinase protein.
Length = 416
Score = 73.3 bits (172), Expect = 9e-13
Identities = 47/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 73.3 bits (172), Expect = 9e-13
Identities = 47/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 73.3 bits (172), Expect = 9e-13
Identities = 47/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 73.3 bits (172), Expect = 9e-13
Identities = 47/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related
kinase (MST4) protein.
Length = 416
Score = 73.3 bits (172), Expect = 9e-13
Identities = 47/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens
cDNA FLJ90669 fis, clone PLACE1005519, moderately
similar to Homo sapiens STE20-like kinase 3 (mst-3)
mRNA. ).
Length = 392
Score = 73.3 bits (172), Expect = 9e-13
Identities = 47/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 73.3 bits (172), Expect = 9e-13
Identities = 47/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4
protein.
Length = 416
Score = 73.3 bits (172), Expect = 9e-13
Identities = 47/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protein
kinase MASK protein.
Length = 416
Score = 73.3 bits (172), Expect = 9e-13
Identities = 47/184 (25%), Positives = 91/184 (49%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G +L+ A + Q +R + W++PEV++Q+ YD ++DI
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--AYDSKADIW 203
Query: 787 PSGV 798
G+
Sbjct: 204 SLGI 207
>BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein.
Length = 812
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/192 (25%), Positives = 89/192 (46%), Gaps = 5/192 (2%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
GA Y +YK +T A+K +D G + ++L QQ++ +E H N++ Y+ S++
Sbjct: 23 GAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSL-QQEITILRECRHPNVVAYIGSYL 81
Query: 406 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 585
L++ GS ++I P + E A V R+ L+ L +LH Q IHR ++
Sbjct: 82 RNDRLWICMEFCGGGSLQEIYHATGP--LEERQIAYVCREALKGLHHLHSQGKIHRDIKG 139
Query: 586 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLK-G 762
+++L+ G +L+ + + ++R W++PEV K G
Sbjct: 140 ANLLLTLQGDVKLADFGVSGELTASVAKRRSF---------IGTPYWMAPEVAAVERKGG 190
Query: 763 YDERSDITPSGV 798
Y+E D+ G+
Sbjct: 191 YNELCDVWALGI 202
>BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated kinase
7 protein.
Length = 719
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/223 (27%), Positives = 109/223 (48%), Gaps = 3/223 (1%)
Frame = +1
Query: 142 VHSSKLRFILEML-SP-DINDYQLTSI-ITECSDGGAVVYSALYKPNNTKVAIKRYFVDR 312
V + R L+++ SP D +Y I I E S G +V A K +VA+K+ + R
Sbjct: 427 VSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTG--IVCIATEKHTGKQVAVKKMDL-R 483
Query: 313 GKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI 492
+++ L+ +V+ ++ HH N++ +S++ G EL+VV + G+ DI+ +
Sbjct: 484 KQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTH---TRM 540
Query: 493 SELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQ 672
+E A V VL+AL YLH Q IHR +++ +L+ ++G +LS A + ++
Sbjct: 541 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 600
Query: 673 RKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ L W++PEV+ + Y DI G++
Sbjct: 601 KSL---------VGTPYWMAPEVISR--LPYGTEVDIWSLGIM 632
>AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated kinase
7 protein.
Length = 719
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/223 (27%), Positives = 109/223 (48%), Gaps = 3/223 (1%)
Frame = +1
Query: 142 VHSSKLRFILEML-SP-DINDYQLTSI-ITECSDGGAVVYSALYKPNNTKVAIKRYFVDR 312
V + R L+++ SP D +Y I I E S G +V A K +VA+K+ + R
Sbjct: 427 VSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTG--IVCIATEKHTGKQVAVKKMDL-R 483
Query: 313 GKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI 492
+++ L+ +V+ ++ HH N++ +S++ G EL+VV + G+ DI+ +
Sbjct: 484 KQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTH---TRM 540
Query: 493 SELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQ 672
+E A V VL+AL YLH Q IHR +++ +L+ ++G +LS A + ++
Sbjct: 541 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 600
Query: 673 RKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ L W++PEV+ + Y DI G++
Sbjct: 601 KSL---------VGTPYWMAPEVISR--LPYGTEVDIWSLGIM 632
>AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated kinase
7 protein.
Length = 719
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/223 (27%), Positives = 109/223 (48%), Gaps = 3/223 (1%)
Frame = +1
Query: 142 VHSSKLRFILEML-SP-DINDYQLTSI-ITECSDGGAVVYSALYKPNNTKVAIKRYFVDR 312
V + R L+++ SP D +Y I I E S G +V A K +VA+K+ + R
Sbjct: 427 VSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTG--IVCIATEKHTGKQVAVKKMDL-R 483
Query: 313 GKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI 492
+++ L+ +V+ ++ HH N++ +S++ G EL+VV + G+ DI+ +
Sbjct: 484 KQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTH---TRM 540
Query: 493 SELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQ 672
+E A V VL+AL YLH Q IHR +++ +L+ ++G +LS A + ++
Sbjct: 541 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 600
Query: 673 RKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ L W++PEV+ + Y DI G++
Sbjct: 601 KSL---------VGTPYWMAPEVISR--LPYGTEVDIWSLGIM 632
>AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated kinase
7 protein.
Length = 719
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/223 (27%), Positives = 109/223 (48%), Gaps = 3/223 (1%)
Frame = +1
Query: 142 VHSSKLRFILEML-SP-DINDYQLTSI-ITECSDGGAVVYSALYKPNNTKVAIKRYFVDR 312
V + R L+++ SP D +Y I I E S G +V A K +VA+K+ + R
Sbjct: 427 VSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTG--IVCIATEKHTGKQVAVKKMDL-R 483
Query: 313 GKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI 492
+++ L+ +V+ ++ HH N++ +S++ G EL+VV + G+ DI+ +
Sbjct: 484 KQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTH---TRM 540
Query: 493 SELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQ 672
+E A V VL+AL YLH Q IHR +++ +L+ ++G +LS A + ++
Sbjct: 541 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 600
Query: 673 RKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ L W++PEV+ + Y DI G++
Sbjct: 601 KSL---------VGTPYWMAPEVISR--LPYGTEVDIWSLGIM 632
>AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 protein.
Length = 719
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/223 (27%), Positives = 109/223 (48%), Gaps = 3/223 (1%)
Frame = +1
Query: 142 VHSSKLRFILEML-SP-DINDYQLTSI-ITECSDGGAVVYSALYKPNNTKVAIKRYFVDR 312
V + R L+++ SP D +Y I I E S G +V A K +VA+K+ + R
Sbjct: 427 VSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTG--IVCIATEKHTGKQVAVKKMDL-R 483
Query: 313 GKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI 492
+++ L+ +V+ ++ HH N++ +S++ G EL+VV + G+ DI+ +
Sbjct: 484 KQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTH---TRM 540
Query: 493 SELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQ 672
+E A V VL+AL YLH Q IHR +++ +L+ ++G +LS A + ++
Sbjct: 541 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 600
Query: 673 RKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ L W++PEV+ + Y DI G++
Sbjct: 601 KSL---------VGTPYWMAPEVISR--LPYGTEVDIWSLGIM 632
>AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein.
Length = 753
Score = 69.7 bits (163), Expect = 1e-11
Identities = 61/223 (27%), Positives = 109/223 (48%), Gaps = 3/223 (1%)
Frame = +1
Query: 142 VHSSKLRFILEML-SP-DINDYQLTSI-ITECSDGGAVVYSALYKPNNTKVAIKRYFVDR 312
V + R L+++ SP D +Y I I E S G +V A K +VA+K+ + R
Sbjct: 461 VSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTG--IVCIATEKHTGKQVAVKKMDL-R 517
Query: 313 GKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGI 492
+++ L+ +V+ ++ HH N++ +S++ G EL+VV + G+ DI+ +
Sbjct: 518 KQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTH---TRM 574
Query: 493 SELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQ 672
+E A V VL+AL YLH Q IHR +++ +L+ ++G +LS A + ++
Sbjct: 575 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 634
Query: 673 RKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
+ L W++PEV+ + Y DI G++
Sbjct: 635 KSL---------VGTPYWMAPEVISR--LPYGTEVDIWSLGIM 666
>U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein.
Length = 819
Score = 68.5 bits (160), Expect = 3e-11
Identities = 49/192 (25%), Positives = 89/192 (46%), Gaps = 5/192 (2%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
GA Y +YK +T A+K +D G + ++L QQ++ +E H N++ Y+ S++
Sbjct: 22 GAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSL-QQEITILRECRHPNVVAYIGSYL 80
Query: 406 HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRA 585
L++ GS ++I P + E A V R+ L+ L +LH Q IHR ++
Sbjct: 81 RNDRLWICMEFCGGGSLQEIYHATGP--LEERQIAYVCRERLKGLHHLHSQGKIHRDIKG 138
Query: 586 SHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLK-G 762
+++L+ G +L+ + + ++R W++PEV K G
Sbjct: 139 ANLLLTLQGDVKLADFGVSGELTASVAKRRSF---------IGTPYWMAPEVAAVERKGG 189
Query: 763 YDERSDITPSGV 798
Y+E D+ G+
Sbjct: 190 YNELCDVWALGI 201
>AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protein
kinase MST4a protein.
Length = 354
Score = 67.3 bits (157), Expect = 6e-11
Identities = 44/176 (25%), Positives = 86/176 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ + VAIK ++ +++ IQQ++ + + + Y S++ G +L++
Sbjct: 38 VFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
+ + GS D+L R P E A +L+++L+ L YLH + IHR ++A++VL+
Sbjct: 98 IMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDER 774
G +L+ A + Q +R + W++PEV++Q+ YD +
Sbjct: 155 QGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--AYDSK 199
>U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase
kinase kinase 5 protein.
Length = 1374
Score = 66.9 bits (156), Expect = 8e-11
Identities = 44/186 (23%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDF---------GTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 778 DITPSG 795
DI G
Sbjct: 863 DIWSLG 868
>D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulating
kinase 1 protein.
Length = 1374
Score = 66.9 bits (156), Expect = 8e-11
Identities = 44/186 (23%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDF---------GTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 778 DITPSG 795
DI G
Sbjct: 863 DIWSLG 868
>BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 66.9 bits (156), Expect = 8e-11
Identities = 44/186 (23%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDF---------GTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 778 DITPSG 795
DI G
Sbjct: 863 DIWSLG 868
>BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 66.9 bits (156), Expect = 8e-11
Identities = 44/186 (23%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDF---------GTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 778 DITPSG 795
DI G
Sbjct: 863 DIWSLG 868
>BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein.
Length = 681
Score = 66.9 bits (156), Expect = 8e-11
Identities = 49/186 (26%), Positives = 92/186 (49%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+V A K + +VA+K + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 420 IVCLAREKHSGRQVAVKMMDL-RKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELW 478
Query: 424 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 603
V+ + G+ DI+ + ++E A V VLQAL YLH Q IHR +++ +L+
Sbjct: 479 VLMEFLQGGALTDIVSQV---RLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLT 535
Query: 604 ANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDI 783
+G +LS A + +++ L W++PEV+ ++L Y DI
Sbjct: 536 LDGRVKLSDFGFCAQISKDVPKRKSL---------VGTPYWMAPEVISRSL--YATEVDI 584
Query: 784 TPSGVL 801
G++
Sbjct: 585 WSLGIM 590
>AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 66.9 bits (156), Expect = 8e-11
Identities = 44/186 (23%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDF---------GTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 778 DITPSG 795
DI G
Sbjct: 863 DIWSLG 868
>AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 66.9 bits (156), Expect = 8e-11
Identities = 44/186 (23%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 693 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 751
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE++++ +GY + +
Sbjct: 812 NTYSGVLKISDF---------GTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 862
Query: 778 DITPSG 795
DI G
Sbjct: 863 DIWSLG 868
>AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein.
Length = 681
Score = 66.9 bits (156), Expect = 8e-11
Identities = 49/186 (26%), Positives = 92/186 (49%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+V A K + +VA+K + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 420 IVCLAREKHSGRQVAVKMMDL-RKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELW 478
Query: 424 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 603
V+ + G+ DI+ + ++E A V VLQAL YLH Q IHR +++ +L+
Sbjct: 479 VLMEFLQGGALTDIVSQV---RLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLT 535
Query: 604 ANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDI 783
+G +LS A + +++ L W++PEV+ ++L Y DI
Sbjct: 536 LDGRVKLSDFGFCAQISKDVPKRKSL---------VGTPYWMAPEVISRSL--YATEVDI 584
Query: 784 TPSGVL 801
G++
Sbjct: 585 WSLGIM 590
>AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein
kinase 6 protein.
Length = 681
Score = 66.9 bits (156), Expect = 8e-11
Identities = 49/186 (26%), Positives = 92/186 (49%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+V A K + +VA+K + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 420 IVCLAREKHSGRQVAVKMMDL-RKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELW 478
Query: 424 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 603
V+ + G+ DI+ + ++E A V VLQAL YLH Q IHR +++ +L+
Sbjct: 479 VLMEFLQGGALTDIVSQV---RLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLT 535
Query: 604 ANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDI 783
+G +LS A + +++ L W++PEV+ ++L Y DI
Sbjct: 536 LDGRVKLSDFGFCAQISKDVPKRKSL---------VGTPYWMAPEVISRSL--YATEVDI 584
Query: 784 TPSGVL 801
G++
Sbjct: 585 WSLGIM 590
>AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 variant protein.
Length = 1455
Score = 66.9 bits (156), Expect = 8e-11
Identities = 44/186 (23%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL SF +
Sbjct: 773 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIK 831
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P +E + +L+ L+YLH +HR ++ +VLI
Sbjct: 832 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLI 891
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE++++ +GY + +
Sbjct: 892 NTYSGVLKISDF---------GTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAA 942
Query: 778 DITPSG 795
DI G
Sbjct: 943 DIWSLG 948
>BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 1/185 (0%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 227 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 285
Query: 424 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 286 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 345
Query: 601 GANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSD 780
SGL + G +R + + L +++PE+++Q +GY + +D
Sbjct: 346 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 397
Query: 781 ITPSG 795
I G
Sbjct: 398 IWSLG 402
>BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 1/185 (0%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 227 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 285
Query: 424 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 286 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 345
Query: 601 GANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSD 780
SGL + G +R + + L +++PE+++Q +GY + +D
Sbjct: 346 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 397
Query: 781 ITPSG 795
I G
Sbjct: 398 IWSLG 402
>BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein.
Length = 441
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 1/185 (0%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 130 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 188
Query: 424 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 189 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 248
Query: 601 GANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSD 780
SGL + G +R + + L +++PE+++Q +GY + +D
Sbjct: 249 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 300
Query: 781 ITPSG 795
I G
Sbjct: 301 IWSLG 305
>BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein.
Length = 797
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 1/185 (0%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 384 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 442
Query: 424 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 443 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 502
Query: 601 GANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSD 780
SGL + G +R + + L +++PE+++Q +GY + +D
Sbjct: 503 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 554
Query: 781 ITPSG 795
I G
Sbjct: 555 IWSLG 559
>AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 797
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 1/185 (0%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 384 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 442
Query: 424 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 443 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 502
Query: 601 GANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSD 780
SGL + G +R + + L +++PE+++Q +GY + +D
Sbjct: 503 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 554
Query: 781 ITPSG 795
I G
Sbjct: 555 IWSLG 559
>AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1288
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 1/185 (0%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 661 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 719
Query: 424 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 720 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 779
Query: 601 GANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSD 780
SGL + G +R + + L +++PE+++Q +GY + +D
Sbjct: 780 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 831
Query: 781 ITPSG 795
I G
Sbjct: 832 IWSLG 836
>AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1011
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 1/185 (0%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 384 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 442
Query: 424 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 443 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 502
Query: 601 GANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSD 780
SGL + G +R + + L +++PE+++Q +GY + +D
Sbjct: 503 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 554
Query: 781 ITPSG 795
I G
Sbjct: 555 IWSLG 559
>AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 variant protein.
Length = 1192
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 1/185 (0%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 565 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 623
Query: 424 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 624 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 683
Query: 601 GANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSD 780
SGL + G +R + + L +++PE+++Q +GY + +D
Sbjct: 684 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 735
Query: 781 ITPSG 795
I G
Sbjct: 736 IWSLG 740
>AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regulating
kinase 2 protein.
Length = 1288
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 1/185 (0%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
VVY+ + ++AIK +R + + +++ + L H NI+ YL S G L
Sbjct: 661 VVYAGRDRHTRVRIAIKE-IPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLK 719
Query: 424 VVSPLMSFGSCRDILDRYF-PEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L + P +E + R +LQ L YLH +HR ++ +VLI
Sbjct: 720 IFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLI 779
Query: 601 GANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSD 780
SGL + G +R + + L +++PE+++Q +GY + +D
Sbjct: 780 NT-----FSGLLKISDF---GTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAAD 831
Query: 781 ITPSG 795
I G
Sbjct: 832 IWSLG 836
>AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinase
transcript variant 4 protein.
Length = 510
Score = 65.3 bits (152), Expect = 2e-10
Identities = 43/176 (24%), Positives = 82/176 (46%), Gaps = 5/176 (2%)
Frame = +1
Query: 283 VAIKRYFVDRGKEKAT-----LIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSF 447
+A+K+ +D + A +Q++V K L H NI+ YL + + + + +
Sbjct: 268 IAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPG 327
Query: 448 GSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLS 627
GS I++R+ P + E+ + +LQ + YLH+ +HR ++ ++V++ G+ +L
Sbjct: 328 GSISSIINRFGP--LPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLI 385
Query: 628 GLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSG 795
A + G +L + W++PEV+ N GY +SDI G
Sbjct: 386 DFGCARRLAWAGLNGTHSDMLKSM---HGTPYWMAPEVI--NESGYGRKSDIWSIG 436
>AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinase
transcript variant 2 protein.
Length = 1215
Score = 65.3 bits (152), Expect = 2e-10
Identities = 43/176 (24%), Positives = 82/176 (46%), Gaps = 5/176 (2%)
Frame = +1
Query: 283 VAIKRYFVDRGKEKAT-----LIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSF 447
+A+K+ +D + A +Q++V K L H NI+ YL + + + + +
Sbjct: 973 IAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPG 1032
Query: 448 GSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLS 627
GS I++R+ P + E+ + +LQ + YLH+ +HR ++ ++V++ G+ +L
Sbjct: 1033 GSISSIINRFGP--LPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLI 1090
Query: 628 GLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSG 795
A + G +L + W++PEV+ N GY +SDI G
Sbjct: 1091 DFGCARRLAWAGLNGTHSDMLKSM---HGTPYWMAPEVI--NESGYGRKSDIWSIG 1141
>AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinase
transcript variant 1 protein.
Length = 1328
Score = 65.3 bits (152), Expect = 2e-10
Identities = 43/176 (24%), Positives = 82/176 (46%), Gaps = 5/176 (2%)
Frame = +1
Query: 283 VAIKRYFVDRGKEKAT-----LIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSF 447
+A+K+ +D + A +Q++V K L H NI+ YL + + + + +
Sbjct: 1086 IAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPG 1145
Query: 448 GSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLS 627
GS I++R+ P + E+ + +LQ + YLH+ +HR ++ ++V++ G+ +L
Sbjct: 1146 GSISSIINRFGP--LPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLI 1203
Query: 628 GLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSG 795
A + G +L + W++PEV+ N GY +SDI G
Sbjct: 1204 DFGCARRLAWAGLNGTHSDMLKSM---HGTPYWMAPEVI--NESGYGRKSDIWSIG 1254
>AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 65.3 bits (152), Expect = 2e-10
Identities = 38/137 (27%), Positives = 72/137 (52%)
Frame = +1
Query: 388 YLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
Y S++ +L+++ + GS D+L+ P + E A +LR++L+ L YLH + I
Sbjct: 2 YYGSYLKDTKLWIIMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKI 58
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLE 747
HR ++A++VL+ +G +L+ A + Q +R + W++PEV++
Sbjct: 59 HRDIKAANVLLSEHGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIK 109
Query: 748 QNLKGYDERSDITPSGV 798
Q+ YD ++DI G+
Sbjct: 110 QS--AYDSKADIWSLGI 124
>AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 65.3 bits (152), Expect = 2e-10
Identities = 38/137 (27%), Positives = 72/137 (52%)
Frame = +1
Query: 388 YLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
Y S++ +L+++ + GS D+L+ P + E A +LR++L+ L YLH + I
Sbjct: 2 YYGSYLKDTKLWIIMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKKI 58
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLE 747
HR ++A++VL+ +G +L+ A + Q +R + W++PEV++
Sbjct: 59 HRDIKAANVLLSEHGEVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIK 109
Query: 748 QNLKGYDERSDITPSGV 798
Q+ YD ++DI G+
Sbjct: 110 QS--AYDSKADIWSLGI 124
>AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens
cDNA FLJ16645 fis, clone TESTI4031745, moderately
similar to Mitogen-activated protein kinase kinase
kinase 5 (EC ).
Length = 788
Score = 63.3 bits (147), Expect = 1e-09
Identities = 44/186 (23%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 140 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 198
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 199 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 256
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S L G +R + + L +++PE+++Q +GY +
Sbjct: 257 NTYSGVVKISDL---------GTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 307
Query: 778 DITPSG 795
DI G
Sbjct: 308 DIWSLG 313
>Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/184 (24%), Positives = 90/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 208
Query: 787 PSGV 798
G+
Sbjct: 209 SLGI 212
>Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/184 (24%), Positives = 90/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 208
Query: 787 PSGV 798
G+
Sbjct: 209 SLGI 212
>U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein
kinase Krs-2 protein.
Length = 487
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/184 (24%), Positives = 90/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 208
Query: 787 PSGV 798
G+
Sbjct: 209 SLGI 212
>U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein.
Length = 487
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/184 (24%), Positives = 90/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 208
Query: 787 PSGV 798
G+
Sbjct: 209 SLGI 212
>BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/184 (24%), Positives = 90/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 208
Query: 787 PSGV 798
G+
Sbjct: 209 SLGI 212
>BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/184 (24%), Positives = 90/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 208
Query: 787 PSGV 798
G+
Sbjct: 209 SLGI 212
>BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for
IMAGE:4400771) protein.
Length = 405
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/184 (24%), Positives = 90/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 208
Query: 787 PSGV 798
G+
Sbjct: 209 SLGI 212
>AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/184 (24%), Positives = 90/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 208
Query: 787 PSGV 798
G+
Sbjct: 209 SLGI 212
>AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/184 (24%), Positives = 90/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 160 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 208
Query: 787 PSGV 798
G+
Sbjct: 209 SLGI 212
>AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase 4
variant protein.
Length = 511
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/184 (24%), Positives = 90/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 68 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 124
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 125 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 183
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 184 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 232
Query: 787 PSGV 798
G+
Sbjct: 233 SLGI 236
>AY574905-1|AAT81414.1| 462|Homo sapiens regulated in COPD kinase
transcript variant 5 protein.
Length = 462
Score = 62.5 bits (145), Expect = 2e-09
Identities = 41/169 (24%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = +1
Query: 292 KRYFVDRG-KEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDIL 468
K+ F + K + ++ V K L H NI+ YL + + + + + GS I+
Sbjct: 227 KKIFSENSLKSEEPILWTKVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSII 286
Query: 469 DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAAS 648
+R+ P + E+ + +LQ + YLH+ +HR ++ ++V++ G+ +L A
Sbjct: 287 NRFGP--LPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARR 344
Query: 649 MMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSG 795
+ G +L + W++PEV+ N GY +SDI G
Sbjct: 345 LAWAGLNGTHSDMLKSM---HGTPYWMAPEVI--NESGYGRKSDIWSIG 388
>BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 61.7 bits (143), Expect = 3e-09
Identities = 36/135 (26%), Positives = 70/135 (51%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY A++K VAIK+ V+ ++ I +++ ++ +++ Y S+ +L++
Sbjct: 44 VYKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTDLWI 100
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + ++E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 101 VMEYCGAGSVSDII-RLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
Query: 607 NGVARLSGLRTAASM 651
G A+L+ A +
Sbjct: 160 EGHAKLADFGVAGQL 174
>AL732423-2|CAM17478.1| 788|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 788
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/186 (23%), Positives = 85/186 (45%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 140 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 198
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 199 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 256
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE+++Q +GY +
Sbjct: 257 NTYSGVVKISDF---------GTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 307
Query: 778 DITPSG 795
DI G
Sbjct: 308 DIWSLG 313
>AL732423-1|CAM17479.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/186 (23%), Positives = 85/186 (45%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 100 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 158
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 159 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 216
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE+++Q +GY +
Sbjct: 217 NTYSGVVKISDF---------GTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 267
Query: 778 DITPSG 795
DI G
Sbjct: 268 DIWSLG 273
>AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 788
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/186 (23%), Positives = 85/186 (45%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 140 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 198
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 199 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 256
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE+++Q +GY +
Sbjct: 257 NTYSGVVKISDF---------GTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 307
Query: 778 DITPSG 795
DI G
Sbjct: 308 DIWSLG 313
>AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/186 (23%), Positives = 85/186 (45%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 100 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 158
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 159 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 216
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE+++Q +GY +
Sbjct: 217 NTYSGVVKISDF---------GTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 267
Query: 778 DITPSG 795
DI G
Sbjct: 268 DIWSLG 273
>AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens
cDNA FLJ16518 fis, clone NT2RI3007443, moderately
similar to MITOGEN-ACTIVATED PROTEIN KINASE KINASE
KINASE 5 (EC ).
Length = 748
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/186 (23%), Positives = 85/186 (45%), Gaps = 2/186 (1%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+VY+ N ++AIK +R + + +++ K L H NI+ YL S +
Sbjct: 100 IVYAGRDLSNQVRIAIKE-IPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIK 158
Query: 424 VVSPLMSFGSCRDIL-DRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
+ + GS +L ++ P + E + +L+ L+YLH+ +HR ++ +VL+
Sbjct: 159 IFMEQVPGGSLSALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLV 216
Query: 601 GA-NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+GV ++S G +R + + L +++PE+++Q +GY +
Sbjct: 217 NTYSGVVKISDF---------GTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPA 267
Query: 778 DITPSG 795
DI G
Sbjct: 268 DIWSLG 273
>X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein.
Length = 451
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/185 (26%), Positives = 85/185 (45%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ L+K + +VAIK D + ++Q ++ K+L H +IL A G +Y+
Sbjct: 205 VFEGLWK-DRVQVAIKVISRDNLLHQQ-MLQSEIQAMKKLRHKHILALYAVVSVGDPVYI 262
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
++ LM+ GS ++L + + + V + + YL Q YIHR + A ++L+G
Sbjct: 263 ITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGE 322
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
N + ++ A R K + DH N W +PE L + Y +SD+
Sbjct: 323 NTLCKVGDFGLA--------RLIKEDVYLSHDH-NIPYKWTAPEALSRG--HYSTKSDVW 371
Query: 787 PSGVL 801
G+L
Sbjct: 372 SFGIL 376
>U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein
tyrosine kinase protein.
Length = 451
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/185 (26%), Positives = 85/185 (45%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ L+K + +VAIK D + ++Q ++ K+L H +IL A G +Y+
Sbjct: 205 VFEGLWK-DRVQVAIKVISRDNLLHQQ-MLQSEIQAMKKLRHKHILALYAVVSVGDPVYI 262
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
++ LM+ GS ++L + + + V + + YL Q YIHR + A ++L+G
Sbjct: 263 ITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGE 322
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
N + ++ A R K + DH N W +PE L + Y +SD+
Sbjct: 323 NTLCKVGDFGLA--------RLIKEDVYLSHDH-NIPYKWTAPEALSRG--HYSTKSDVW 371
Query: 787 PSGVL 801
G+L
Sbjct: 372 SFGIL 376
>BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein.
Length = 625
Score = 60.5 bits (140), Expect = 7e-09
Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein.
Length = 664
Score = 60.5 bits (140), Expect = 7e-09
Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein.
Length = 247
Score = 60.5 bits (140), Expect = 7e-09
Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine
kinase 6 protein.
Length = 451
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/185 (26%), Positives = 85/185 (45%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ L+K + +VAIK D + ++Q ++ K+L H +IL A G +Y+
Sbjct: 205 VFEGLWK-DRVQVAIKVISRDNLLHQQ-MLQSEIQAMKKLRHKHILALYAVVSVGDPVYI 262
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
++ LM+ GS ++L + + + V + + YL Q YIHR + A ++L+G
Sbjct: 263 ITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGE 322
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
N + ++ A R K + DH N W +PE L + Y +SD+
Sbjct: 323 NTLCKVGDFGLA--------RLIKEDVYLSHDH-NIPYKWTAPEALSRG--HYSTKSDVW 371
Query: 787 PSGVL 801
G+L
Sbjct: 372 SFGIL 376
>BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein.
Length = 501
Score = 60.5 bits (140), Expect = 7e-09
Identities = 40/146 (27%), Positives = 74/146 (50%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 244 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 302
Query: 424 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 603
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 303 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 359
Query: 604 ANGVARLSGLRTAASMMVRGQRQRKL 681
+G +LS A + R++ L
Sbjct: 360 HDGRVKLSDFGFCAQVSKEVPRRKSL 385
>BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 591
Score = 60.5 bits (140), Expect = 7e-09
Identities = 40/146 (27%), Positives = 74/146 (50%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 334 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 392
Query: 424 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 603
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 393 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 449
Query: 604 ANGVARLSGLRTAASMMVRGQRQRKL 681
+G +LS A + R++ L
Sbjct: 450 HDGRVKLSDFGFCAQVSKEVPRRKSL 475
>BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 591
Score = 60.5 bits (140), Expect = 7e-09
Identities = 40/146 (27%), Positives = 74/146 (50%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 334 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 392
Query: 424 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 603
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 393 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 449
Query: 604 ANGVARLSGLRTAASMMVRGQRQRKL 681
+G +LS A + R++ L
Sbjct: 450 HDGRVKLSDFGFCAQVSKEVPRRKSL 475
>BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 426
Score = 60.5 bits (140), Expect = 7e-09
Identities = 40/146 (27%), Positives = 74/146 (50%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 169 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 227
Query: 424 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 603
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 228 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 284
Query: 604 ANGVARLSGLRTAASMMVRGQRQRKL 681
+G +LS A + R++ L
Sbjct: 285 HDGRVKLSDFGFCAQVSKEVPRRKSL 310
>AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 60.5 bits (140), Expect = 7e-09
Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 60.5 bits (140), Expect = 7e-09
Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 60.5 bits (140), Expect = 7e-09
Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein.
Length = 247
Score = 60.5 bits (140), Expect = 7e-09
Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 60.5 bits (140), Expect = 7e-09
Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 60.5 bits (140), Expect = 7e-09
Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>AL121829-13|CAC15525.1| 451|Homo sapiens PTK6 protein.
Length = 451
Score = 60.5 bits (140), Expect = 7e-09
Identities = 49/185 (26%), Positives = 85/185 (45%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ L+K + +VAIK D + ++Q ++ K+L H +IL A G +Y+
Sbjct: 205 VFEGLWK-DRVQVAIKVISRDNLLHQQ-MLQSEIQAMKKLRHKHILALYAVVSVGDPVYI 262
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
++ LM+ GS ++L + + + V + + YL Q YIHR + A ++L+G
Sbjct: 263 ITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGE 322
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
N + ++ A R K + DH N W +PE L + Y +SD+
Sbjct: 323 NTLCKVGDFGLA--------RLIKEDVYLSHDH-NIPYKWTAPEALSRG--HYSTKSDVW 371
Query: 787 PSGVL 801
G+L
Sbjct: 372 SFGIL 376
>AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein.
Length = 591
Score = 60.5 bits (140), Expect = 7e-09
Identities = 40/146 (27%), Positives = 74/146 (50%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 334 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 392
Query: 424 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 603
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 393 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 449
Query: 604 ANGVARLSGLRTAASMMVRGQRQRKL 681
+G +LS A + R++ L
Sbjct: 450 HDGRVKLSDFGFCAQVSKEVPRRKSL 475
>AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein.
Length = 1615
Score = 60.5 bits (140), Expect = 7e-09
Identities = 60/217 (27%), Positives = 101/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase
protein.
Length = 591
Score = 60.5 bits (140), Expect = 7e-09
Identities = 40/146 (27%), Positives = 74/146 (50%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 334 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 392
Query: 424 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 603
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 393 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 449
Query: 604 ANGVARLSGLRTAASMMVRGQRQRKL 681
+G +LS A + R++ L
Sbjct: 450 HDGRVKLSDFGFCAQVSKEVPRRKSL 475
>AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein.
Length = 467
Score = 60.5 bits (140), Expect = 7e-09
Identities = 40/146 (27%), Positives = 74/146 (50%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELY 423
+V A + + VA+K+ + R +++ L+ +V+ ++ H N++ S++ G EL+
Sbjct: 210 IVCIATVRSSGKLVAVKKMDL-RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELW 268
Query: 424 VVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIG 603
VV + G+ DI+ ++E A V VLQAL LH Q IHR +++ +L+
Sbjct: 269 VVMEFLEGGALTDIVTH---TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLT 325
Query: 604 ANGVARLSGLRTAASMMVRGQRQRKL 681
+G +LS A + R++ L
Sbjct: 326 HDGRVKLSDFGFCAQVSKEVPRRKSL 351
>U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein
kinase Krs-1 protein.
Length = 491
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/184 (23%), Positives = 89/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ A++K + VAIK+ V+ ++ I +++ ++ ++ Y S+ +L++
Sbjct: 41 VFKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYVVKYYGSYFKNTDLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + + E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 98 VMEYCGAGSVSDII-RLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNT 156
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 157 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 205
Query: 787 PSGV 798
G+
Sbjct: 206 SLGI 209
>U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein.
Length = 491
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/184 (23%), Positives = 89/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ A++K + VAIK+ V+ ++ I +++ ++ ++ Y S+ +L++
Sbjct: 41 VFKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYVVKYYGSYFKNTDLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + + E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 98 VMEYCGAGSVSDII-RLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNT 156
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 157 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 205
Query: 787 PSGV 798
G+
Sbjct: 206 SLGI 209
>BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase 3
(STE20 homolog, yeast) protein.
Length = 491
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/184 (23%), Positives = 89/184 (48%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
V+ A++K + VAIK+ V+ ++ I +++ ++ ++ Y S+ +L++
Sbjct: 41 VFKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYVVKYYGSYFKNTDLWI 97
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V GS DI+ R + + E A +L+ L+ L+YLH IHR ++A ++L+
Sbjct: 98 VMEYCGAGSVSDII-RLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNT 156
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERSDIT 786
G A+L+ A + ++ + W++PEV+++ GY+ +DI
Sbjct: 157 EGHAKLADFGVAGQLTDTMAKRNTV---------IGTPFWMAPEVIQE--IGYNCVADIW 205
Query: 787 PSGV 798
G+
Sbjct: 206 SLGI 209
>AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein.
Length = 968
Score = 60.1 bits (139), Expect = 9e-09
Identities = 53/214 (24%), Positives = 98/214 (45%), Gaps = 5/214 (2%)
Frame = +1
Query: 172 EMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQD 345
E + D++ ++ I+ E DG VY A K A K +E + +++ +
Sbjct: 24 EHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIE 83
Query: 346 VLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRD 525
+L + H I+ L ++ H +L+++ G+ D + G++E +V R
Sbjct: 84 ILATCD--HPYIVKLLGAYYHDGKLWIMIEFCPGGAV-DAIMLELDRGLTEPQIQVVCRQ 140
Query: 526 VLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDH 705
+L+AL +LH + IHR ++A +VL+ G RL+ +A + L L D
Sbjct: 141 MLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSA---------KNLKTLQKRDS 191
Query: 706 DNANLMWLSPEVLE-QNLKG--YDERSDITPSGV 798
W++PEV+ + +K YD ++DI G+
Sbjct: 192 FIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGI 225
>BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein.
Length = 1235
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Frame = +1
Query: 202 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 372
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 552
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 553 KQLYIHRSVRASHVLIGANGVARLSGLRTAASM 651
IHR V+A ++L+ G+ +L +A+ M
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSASIM 176
>BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein.
Length = 1235
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Frame = +1
Query: 202 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 372
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 552
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 553 KQLYIHRSVRASHVLIGANGVARLSGLRTAASM 651
IHR V+A ++L+ G+ +L +A+ M
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSASIM 176
>BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein.
Length = 1426
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Frame = +1
Query: 202 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 372
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 210 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 269
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 552
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 270 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 327
Query: 553 KQLYIHRSVRASHVLIGANGVARLSGLRTAASM 651
IHR V+A ++L+ G+ +L +A+ M
Sbjct: 328 SHNMIHRDVKAGNILLSEPGLVKLGDFGSASIM 360
>BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein.
Length = 560
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Frame = +1
Query: 202 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 372
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 552
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 553 KQLYIHRSVRASHVLIGANGVARLSGLRTAASM 651
IHR V+A ++L+ G+ +L +A+ M
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSASIM 176
>BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for
IMAGE:3878048) protein.
Length = 762
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Frame = +1
Query: 202 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 372
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 552
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 553 KQLYIHRSVRASHVLIGANGVARLSGLRTAASM 651
IHR V+A ++L+ G+ +L +A+ M
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSASIM 176
>AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein.
Length = 1049
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Frame = +1
Query: 202 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 372
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 552
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 553 KQLYIHRSVRASHVLIGANGVARLSGLRTAASM 651
IHR V+A ++L+ G+ +L +A+ M
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSASIM 176
>AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived
STE20-like kinase PSK protein.
Length = 1235
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Frame = +1
Query: 202 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 372
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 26 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 85
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 552
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 86 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 143
Query: 553 KQLYIHRSVRASHVLIGANGVARLSGLRTAASM 651
IHR V+A ++L+ G+ +L +A+ M
Sbjct: 144 SHNMIHRDVKAGNILLSEPGLVKLGDFGSASIM 176
>AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein.
Length = 1064
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/153 (29%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Frame = +1
Query: 202 QLTSIITECSDGG-AVVYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHH 372
+L S + E G VY A N+ VAIK+ Y + EK I ++V ++L H
Sbjct: 41 KLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRH 100
Query: 373 ANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLH 552
N + Y ++ ++V GS D+L+ + + + E+ A V LQ L YLH
Sbjct: 101 PNTIQYRGCYLREHTAWLVMEYC-LGSASDLLEVH-KKPLQEVEIAAVTHGALQGLAYLH 158
Query: 553 KQLYIHRSVRASHVLIGANGVARLSGLRTAASM 651
IHR V+A ++L+ G+ +L +A+ M
Sbjct: 159 SHNMIHRDVKAGNILLSEPGLVKLGDFGSASIM 191
>BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase 10
protein.
Length = 968
Score = 59.3 bits (137), Expect = 2e-08
Identities = 54/214 (25%), Positives = 98/214 (45%), Gaps = 5/214 (2%)
Frame = +1
Query: 172 EMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE-KATLIQQD 345
E + D++ ++ I+ E DG VY A K VA K +E + +++ +
Sbjct: 24 EHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALVAAKVIETKSEEELEDYIVEIE 83
Query: 346 VLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRD 525
+L + H I+ L ++ H +L+++ G+ D + G++E V R
Sbjct: 84 ILATCD--HPYIVKLLGAYYHDGKLWIMIEFCPGGAV-DAIMLELDRGLTEPQIQEVCRQ 140
Query: 526 VLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDH 705
+L+AL +LH + IHR ++A +VL+ G RL+ +A + L L D
Sbjct: 141 MLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSA---------KNLKTLQKRDS 191
Query: 706 DNANLMWLSPEVLE-QNLKG--YDERSDITPSGV 798
W++PEV+ + +K YD ++DI G+
Sbjct: 192 FIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGI 225
>BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein.
Length = 247
Score = 59.3 bits (137), Expect = 2e-08
Identities = 60/217 (27%), Positives = 100/217 (46%), Gaps = 12/217 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAGYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXX 696
L + L LQ+LH IHR V+ +++L+ G +L +A + R R+
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL--TSTRHRR------ 182
Query: 697 XDHDNANLMWLSPEVL--EQNL-KGYDERSDITPSGV 798
+ W++PEV+ EQ L YD R D G+
Sbjct: 183 -NTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI 218
>BC034673-1|AAH34673.1| 1332|Homo sapiens misshapen-like kinase 1
(zebrafish) protein.
Length = 1332
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/202 (26%), Positives = 91/202 (45%), Gaps = 15/202 (7%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDV-LTRKELHHANILPYLASF 402
G Y +YK + K AIK V +E+ I+Q++ + +K HH NI Y +F
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE--IKQEINMLKKYSHHRNIATYYGAF 89
Query: 403 V------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLY 564
+ + +L++V GS D++ + E A + R++L+ L +LH
Sbjct: 90 IKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKV 149
Query: 565 IHRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++ +VL+ N +L +A + G+R + W++PEV
Sbjct: 150 IHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEV 199
Query: 742 L--EQNLKG-YDERSDITPSGV 798
+ ++N YD RSDI G+
Sbjct: 200 IACDENPDATYDYRSDIWSLGI 221
>AY775058-1|AAV41830.1| 1312|Homo sapiens misshapen/NIKs-related
kinase isoform beta protein.
Length = 1312
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/202 (26%), Positives = 91/202 (45%), Gaps = 15/202 (7%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDV-LTRKELHHANILPYLASF 402
G Y +YK + K AIK V +E+ I+Q++ + +K HH NI Y +F
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE--IKQEINMLKKYSHHRNIATYYGAF 89
Query: 403 V------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLY 564
+ + +L++V GS D++ + E A + R++L+ L +LH
Sbjct: 90 IKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKV 149
Query: 565 IHRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++ +VL+ N +L +A + G+R + W++PEV
Sbjct: 150 IHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEV 199
Query: 742 L--EQNLKG-YDERSDITPSGV 798
+ ++N YD RSDI G+
Sbjct: 200 IACDENPDATYDYRSDIWSLGI 221
>AB041926-1|BAA94838.1| 1303|Homo sapiens GCK family kinase MINK-2
protein.
Length = 1303
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/202 (26%), Positives = 91/202 (45%), Gaps = 15/202 (7%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDV-LTRKELHHANILPYLASF 402
G Y +YK + K AIK V +E+ I+Q++ + +K HH NI Y +F
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE--IKQEINMLKKYSHHRNIATYYGAF 89
Query: 403 V------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLY 564
+ + +L++V GS D++ + E A + R++L+ L +LH
Sbjct: 90 IKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKV 149
Query: 565 IHRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++ +VL+ N +L +A + G+R + W++PEV
Sbjct: 150 IHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEV 199
Query: 742 L--EQNLKG-YDERSDITPSGV 798
+ ++N YD RSDI G+
Sbjct: 200 IACDENPDATYDYRSDIWSLGI 221
>AB035698-1|BAA90753.1| 1295|Homo sapiens Misshapen/NIK-related
kinase MINK-1 protein.
Length = 1295
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/202 (26%), Positives = 91/202 (45%), Gaps = 15/202 (7%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDV-LTRKELHHANILPYLASF 402
G Y +YK + K AIK V +E+ I+Q++ + +K HH NI Y +F
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEE--IKQEINMLKKYSHHRNIATYYGAF 89
Query: 403 V------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLY 564
+ + +L++V GS D++ + E A + R++L+ L +LH
Sbjct: 90 IKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKV 149
Query: 565 IHRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEV 741
IHR ++ +VL+ N +L +A + G+R + W++PEV
Sbjct: 150 IHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEV 199
Query: 742 L--EQNLKG-YDERSDITPSGV 798
+ ++N YD RSDI G+
Sbjct: 200 IACDENPDATYDYRSDIWSLGI 221
>AY212247-1|AAO32626.1| 1239|Homo sapiens Ste20 group protein kinase
HGK protein.
Length = 1239
Score = 58.0 bits (134), Expect = 4e-08
Identities = 52/201 (25%), Positives = 90/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V +E+ ++ ++L +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML-KKYSHHRNIATYYGAFI 90
Query: 406 ------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
H +L++V GS D++ + E A + R++L+ L +LH I
Sbjct: 91 KKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD RSD+ G+
Sbjct: 201 ACDENPDATYDYRSDLWSCGI 221
>AF096300-1|AAD16137.1| 1165|Homo sapiens HPK/GCK-like kinase HGK
protein.
Length = 1165
Score = 58.0 bits (134), Expect = 4e-08
Identities = 52/201 (25%), Positives = 90/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V +E+ ++ ++L +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML-KKYSHHRNIATYYGAFI 90
Query: 406 ------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
H +L++V GS D++ + E A + R++L+ L +LH I
Sbjct: 91 KKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD RSD+ G+
Sbjct: 201 ACDENPDATYDYRSDLWSCGI 221
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/215 (23%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Frame = +1
Query: 178 LSPDINDYQL--TSIITECSDGGAV---VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQ 342
+SP+ + +++ T I + GG VY ++K + VA+K D + + L +
Sbjct: 228 VSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEA 287
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
V+ KE+ H N++ L Y+++ M++G+ D L + ++ + +
Sbjct: 288 AVM--KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT 345
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
+ A++YL K+ +IHR + A + L+G N + +++ S ++ G
Sbjct: 346 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADF--GLSRLMTGDTYTA-------- 395
Query: 703 HDNAN--LMWLSPEVLEQNLKGYDERSDITPSGVL 801
H A + W +PE L N + +SD+ GVL
Sbjct: 396 HAGAKFPIKWTAPESLAYN--KFSIKSDVWAFGVL 428
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/215 (23%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Frame = +1
Query: 178 LSPDINDYQL--TSIITECSDGGAV---VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQ 342
+SP+ + +++ T I + GG VY ++K + VA+K D + + L +
Sbjct: 228 VSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEA 287
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
V+ KE+ H N++ L Y+++ M++G+ D L + ++ + +
Sbjct: 288 AVM--KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT 345
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
+ A++YL K+ +IHR + A + L+G N + +++ S ++ G
Sbjct: 346 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADF--GLSRLMTGDTYTA-------- 395
Query: 703 HDNAN--LMWLSPEVLEQNLKGYDERSDITPSGVL 801
H A + W +PE L N + +SD+ GVL
Sbjct: 396 HAGAKFPIKWTAPESLAYN--KFSIKSDVWAFGVL 428
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/215 (23%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Frame = +1
Query: 178 LSPDINDYQL--TSIITECSDGGAV---VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQ 342
+SP+ + +++ T I + GG VY ++K + VA+K D + + L +
Sbjct: 247 VSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEA 306
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
V+ KE+ H N++ L Y+++ M++G+ D L + ++ + +
Sbjct: 307 AVM--KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT 364
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
+ A++YL K+ +IHR + A + L+G N + +++ S ++ G
Sbjct: 365 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADF--GLSRLMTGDTYTA-------- 414
Query: 703 HDNAN--LMWLSPEVLEQNLKGYDERSDITPSGVL 801
H A + W +PE L N + +SD+ GVL
Sbjct: 415 HAGAKFPIKWTAPESLAYN--KFSIKSDVWAFGVL 447
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/215 (23%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Frame = +1
Query: 178 LSPDINDYQL--TSIITECSDGGAV---VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQ 342
+SP+ + +++ T I + GG VY ++K + VA+K D + + L +
Sbjct: 228 VSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEA 287
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
V+ KE+ H N++ L Y+++ M++G+ D L + ++ + +
Sbjct: 288 AVM--KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT 345
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
+ A++YL K+ +IHR + A + L+G N + +++ S ++ G
Sbjct: 346 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADF--GLSRLMTGDTYTA-------- 395
Query: 703 HDNAN--LMWLSPEVLEQNLKGYDERSDITPSGVL 801
H A + W +PE L N + +SD+ GVL
Sbjct: 396 HAGAKFPIKWTAPESLAYN--KFSIKSDVWAFGVL 428
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/215 (23%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Frame = +1
Query: 178 LSPDINDYQL--TSIITECSDGGAV---VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQ 342
+SP+ + +++ T I + GG VY ++K + VA+K D + + L +
Sbjct: 247 VSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEA 306
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
V+ KE+ H N++ L Y+++ M++G+ D L + ++ + +
Sbjct: 307 AVM--KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT 364
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
+ A++YL K+ +IHR + A + L+G N + +++ S ++ G
Sbjct: 365 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADF--GLSRLMTGDTYTA-------- 414
Query: 703 HDNAN--LMWLSPEVLEQNLKGYDERSDITPSGVL 801
H A + W +PE L N + +SD+ GVL
Sbjct: 415 HAGAKFPIKWTAPESLAYN--KFSIKSDVWAFGVL 447
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/215 (23%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Frame = +1
Query: 178 LSPDINDYQL--TSIITECSDGGAV---VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQ 342
+SP+ + +++ T I + GG VY ++K + VA+K D + + L +
Sbjct: 247 VSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEA 306
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
V+ KE+ H N++ L Y+++ M++G+ D L + ++ + +
Sbjct: 307 AVM--KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT 364
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
+ A++YL K+ +IHR + A + L+G N + +++ S ++ G
Sbjct: 365 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADF--GLSRLMTGDTYTA-------- 414
Query: 703 HDNAN--LMWLSPEVLEQNLKGYDERSDITPSGVL 801
H A + W +PE L N + +SD+ GVL
Sbjct: 415 HAGAKFPIKWTAPESLAYN--KFSIKSDVWAFGVL 447
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/215 (23%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Frame = +1
Query: 178 LSPDINDYQL--TSIITECSDGGAV---VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQ 342
+SP+ + +++ T I + GG VY ++K + VA+K D + + L +
Sbjct: 247 VSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEA 306
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
V+ KE+ H N++ L Y+++ M++G+ D L + ++ + +
Sbjct: 307 AVM--KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT 364
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
+ A++YL K+ +IHR + A + L+G N + +++ S ++ G
Sbjct: 365 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADF--GLSRLMTGDTYTA-------- 414
Query: 703 HDNAN--LMWLSPEVLEQNLKGYDERSDITPSGVL 801
H A + W +PE L N + +SD+ GVL
Sbjct: 415 HAGAKFPIKWTAPESLAYN--KFSIKSDVWAFGVL 447
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/215 (23%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Frame = +1
Query: 178 LSPDINDYQL--TSIITECSDGGAV---VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQ 342
+SP+ + +++ T I + GG VY ++K + VA+K D + + L +
Sbjct: 247 VSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEA 306
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
V+ KE+ H N++ L Y+++ M++G+ D L + ++ + +
Sbjct: 307 AVM--KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT 364
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
+ A++YL K+ +IHR + A + L+G N + +++ S ++ G
Sbjct: 365 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADF--GLSRLMTGDTYTA-------- 414
Query: 703 HDNAN--LMWLSPEVLEQNLKGYDERSDITPSGVL 801
H A + W +PE L N + +SD+ GVL
Sbjct: 415 HAGAKFPIKWTAPESLAYN--KFSIKSDVWAFGVL 447
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/215 (23%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Frame = +1
Query: 178 LSPDINDYQL--TSIITECSDGGAV---VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQ 342
+SP+ + +++ T I + GG VY ++K + VA+K D + + L +
Sbjct: 228 VSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEA 287
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
V+ KE+ H N++ L Y+++ M++G+ D L + ++ + +
Sbjct: 288 AVM--KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT 345
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
+ A++YL K+ +IHR + A + L+G N + +++ S ++ G
Sbjct: 346 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADF--GLSRLMTGDTYTA-------- 395
Query: 703 HDNAN--LMWLSPEVLEQNLKGYDERSDITPSGVL 801
H A + W +PE L N + +SD+ GVL
Sbjct: 396 HAGAKFPIKWTAPESLAYN--KFSIKSDVWAFGVL 428
>AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens
cDNA FLJ90626 fis, clone PLACE1003135, weakly similar to
SPORULATION-SPECIFIC PROTEIN 1 (EC 2.7.1.-). ).
Length = 339
Score = 57.6 bits (133), Expect = 5e-08
Identities = 37/132 (28%), Positives = 68/132 (51%)
Frame = +1
Query: 403 VHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVR 582
+ G +L+++ + GS D+L R P E A +L+++L+ L YLH + IHR ++
Sbjct: 13 MQGSKLWIIMEYLGGGSALDLL-RAGP--FDEFQIATMLKEILKGLDYLHSEKKIHRDIK 69
Query: 583 ASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKG 762
A++VL+ G +L+ A + Q +R + W++PEV++Q+
Sbjct: 70 AANVLLSEQGDVKLADF-GVAGQLTDTQIKRNTFV--------GTPFWMAPEVIQQS--A 118
Query: 763 YDERSDITPSGV 798
YD ++DI G+
Sbjct: 119 YDSKADIWSLGI 130
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/215 (23%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Frame = +1
Query: 178 LSPDINDYQL--TSIITECSDGGAV---VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQ 342
+SP+ + +++ T I + GG VY ++K + VA+K D + + L +
Sbjct: 265 VSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEA 324
Query: 343 DVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLR 522
V+ KE+ H N++ L Y+++ M++G+ D L + ++ + +
Sbjct: 325 AVM--KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMAT 382
Query: 523 DVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXD 702
+ A++YL K+ +IHR + A + L+G N + +++ S ++ G
Sbjct: 383 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADF--GLSRLMTGDTYTA-------- 432
Query: 703 HDNAN--LMWLSPEVLEQNLKGYDERSDITPSGVL 801
H A + W +PE L N + +SD+ GVL
Sbjct: 433 HAGAKFPIKWTAPESLAYN--KFSIKSDVWAFGVL 465
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 302 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 359
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 360 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 419
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 420 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 467
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 468 VWAFGVL 474
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 302 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 359
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 360 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 419
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 420 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 467
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 468 VWAFGVL 474
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 315 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 372
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 373 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 432
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 433 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 480
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 481 VWAFGVL 487
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 287 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 344
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 345 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 404
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 405 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 452
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 453 VWAFGVL 459
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 302 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 359
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 360 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 419
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 420 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 467
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 468 VWAFGVL 474
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 287 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 344
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 345 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 404
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 405 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 452
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 453 VWAFGVL 459
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 302 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 359
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 360 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 419
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 420 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 467
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 468 VWAFGVL 474
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 287 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 344
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 345 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 404
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 405 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 452
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 453 VWAFGVL 459
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 302 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 359
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 360 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 419
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 420 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 467
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 468 VWAFGVL 474
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 287 VYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTLEPPFYI 344
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
V+ M +G+ D L E ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 345 VTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 404
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N V +++ S ++ G H A + W +PE L N + +SD
Sbjct: 405 NHVVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYNT--FSIKSD 452
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 453 VWAFGVL 459
>AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens
cDNA FLJ90247 fis, clone NT2RM2001902, highly similar to
Homo sapiens mRNA for PAK4 protein. ).
Length = 240
Score = 57.2 bits (132), Expect = 6e-08
Identities = 35/124 (28%), Positives = 63/124 (50%)
Frame = +1
Query: 310 RGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG 489
R +++ L+ +V+ ++ H N++ S++ G EL+VV + G+ DI+
Sbjct: 4 RKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTH---TR 60
Query: 490 ISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQR 669
++E A V VLQAL LH Q IHR +++ +L+ +G +LS A + R
Sbjct: 61 MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPR 120
Query: 670 QRKL 681
++ L
Sbjct: 121 RKSL 124
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 57.2 bits (132), Expect = 6e-08
Identities = 44/187 (23%), Positives = 85/187 (45%), Gaps = 2/187 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGRELYV 426
VY ++K + VA+K D + + L + V+ KE+ H N++ L Y+
Sbjct: 75 VYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVM--KEIKHPNLVQLLGVCTREPPFYI 132
Query: 427 VSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGA 606
++ M++G+ D L + ++ + + + A++YL K+ +IHR + A + L+G
Sbjct: 133 ITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGE 192
Query: 607 NGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNAN--LMWLSPEVLEQNLKGYDERSD 780
N + +++ S ++ G H A + W +PE L N + +SD
Sbjct: 193 NHLVKVADF--GLSRLMTGDTYTA--------HAGAKFPIKWTAPESLAYN--KFSIKSD 240
Query: 781 ITPSGVL 801
+ GVL
Sbjct: 241 VWAFGVL 247
>AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein.
Length = 302
Score = 57.2 bits (132), Expect = 6e-08
Identities = 51/191 (26%), Positives = 89/191 (46%), Gaps = 6/191 (3%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKR---YFVDRGKEKATLIQQ-DVLTRKELHHANILPYLASFVHGR 414
VY A + VA+K+ + + K +A I++ D+L K+L+H N++ Y ASF+
Sbjct: 48 VYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLL--KQLNHPNVIKYYASFIEDN 105
Query: 415 ELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIVLRDVLQALQYLHKQLYIHRSVRAS 588
EL +V L G ++ + + I E + AL+++H + +HR ++ +
Sbjct: 106 ELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPA 165
Query: 589 HVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYD 768
+V I A GV +L L + H L + ++SPE + +N GY+
Sbjct: 166 NVFITATGVVKLGDLGLGRFF---SSKTTAAHSLVGTPY------YMSPERIHEN--GYN 214
Query: 769 ERSDITPSGVL 801
+SDI G L
Sbjct: 215 FKSDIWSLGCL 225
>AB014587-1|BAA31662.1| 1175|Homo sapiens KIAA0687 protein protein.
Length = 1175
Score = 57.2 bits (132), Expect = 6e-08
Identities = 49/194 (25%), Positives = 86/194 (44%), Gaps = 10/194 (5%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV------H 408
VY + AIK V +E+ ++ ++L +K HH NI Y +F+ H
Sbjct: 2 VYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML-KKYSHHRNIATYYGAFIKKSPPGH 60
Query: 409 GRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRAS 588
+L++V GS D++ + E A + R++L+ L +LH IHR ++
Sbjct: 61 DDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQ 120
Query: 589 HVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL--EQNLK 759
+VL+ N +L +A + G+R + W++PEV+ ++N
Sbjct: 121 NVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVIACDENPD 170
Query: 760 G-YDERSDITPSGV 798
YD RSD+ G+
Sbjct: 171 ATYDYRSDLWSCGI 184
>D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein.
Length = 1164
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 26 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 85
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 86 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 142
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 143 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 199
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 200 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 235
>BC150256-1|AAI50257.1| 1360|Homo sapiens TRAF2 and NCK interacting
kinase protein.
Length = 1360
Score = 56.8 bits (131), Expect = 9e-08
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 406 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD +SD+ G+
Sbjct: 201 ACDENPDATYDFKSDLWSLGI 221
>BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein.
Length = 1204
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 14 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 73
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 74 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 130
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 131 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 187
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 188 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
>BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein.
Length = 617
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 14 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 73
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 74 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 130
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 131 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 187
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 188 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
>BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein.
Length = 426
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 14 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 73
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 74 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 130
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 131 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 187
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 188 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
>BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein.
Length = 614
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 14 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 73
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 74 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 130
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 131 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 187
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 188 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
>AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 14 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 73
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 74 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 130
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 131 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 187
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 188 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
>AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 14 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 73
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 74 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 130
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 131 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 187
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 188 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
>AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 14 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 73
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 74 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 130
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 131 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 187
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 188 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
>AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 14 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 73
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 74 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 130
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 131 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 187
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 188 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
>AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20-9
protein.
Length = 1235
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 14 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 73
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 74 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 130
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 131 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 187
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 188 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
>AF172271-1|AAF03789.1| 1268|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 8 protein.
Length = 1268
Score = 56.8 bits (131), Expect = 9e-08
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 406 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD +SD+ G+
Sbjct: 201 ACDENPDATYDFKSDLWSLGI 221
>AF172270-1|AAF03788.1| 1297|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 7 protein.
Length = 1297
Score = 56.8 bits (131), Expect = 9e-08
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 406 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD +SD+ G+
Sbjct: 201 ACDENPDATYDFKSDLWSLGI 221
>AF172269-1|AAF03787.1| 1323|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 6 protein.
Length = 1323
Score = 56.8 bits (131), Expect = 9e-08
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 406 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD +SD+ G+
Sbjct: 201 ACDENPDATYDFKSDLWSLGI 221
>AF172268-1|AAF03786.1| 1276|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 5 protein.
Length = 1276
Score = 56.8 bits (131), Expect = 9e-08
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 406 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD +SD+ G+
Sbjct: 201 ACDENPDATYDFKSDLWSLGI 221
>AF172267-1|AAF03785.1| 1352|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 4 protein.
Length = 1352
Score = 56.8 bits (131), Expect = 9e-08
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 406 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD +SD+ G+
Sbjct: 201 ACDENPDATYDFKSDLWSLGI 221
>AF172266-1|AAF03784.1| 1305|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 3 protein.
Length = 1305
Score = 56.8 bits (131), Expect = 9e-08
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 406 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD +SD+ G+
Sbjct: 201 ACDENPDATYDFKSDLWSLGI 221
>AF172265-1|AAF03783.1| 1331|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 2 protein.
Length = 1331
Score = 56.8 bits (131), Expect = 9e-08
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 406 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD +SD+ G+
Sbjct: 201 ACDENPDATYDFKSDLWSLGI 221
>AF172264-1|AAF03782.1| 1360|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 1 protein.
Length = 1360
Score = 56.8 bits (131), Expect = 9e-08
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 90
Query: 406 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 91 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 150
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 151 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 200
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD +SD+ G+
Sbjct: 201 ACDENPDATYDFKSDLWSLGI 221
>AB011123-1|BAA25477.2| 1385|Homo sapiens KIAA0551 protein protein.
Length = 1385
Score = 56.8 bits (131), Expect = 9e-08
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 14/201 (6%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V G E+ + Q+ + +K HH NI Y +F+
Sbjct: 57 GNGTYGQVYKGRHVKTGQLAAIKVMDVT-GDEEEEIKQEINMLKKYSHHRNIATYYGAFI 115
Query: 406 HGR------ELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
+L++V GS D++ + E A + R++L+ L +LH+ I
Sbjct: 116 KKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVI 175
Query: 568 HRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHLLXXXDHDNANLMWLSPEVL 744
HR ++ +VL+ N +L +A + G+R + W++PEV+
Sbjct: 176 HRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI----------GTPYWMAPEVI 225
Query: 745 --EQNLKG-YDERSDITPSGV 798
++N YD +SD+ G+
Sbjct: 226 ACDENPDATYDFKSDLWSLGI 246
>AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein.
Length = 1204
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Frame = +1
Query: 148 SSKLRFILEMLSPDINDYQLTSIITECSDGG-AVVYSALYKPNNTKVAIKRYFVDRGKE- 321
S K + E + D+N II E DG VY A K + A K +E
Sbjct: 14 SEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEEL 73
Query: 322 KATLIQQDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISEL 501
+ +++ D+L + H NI+ L +F + L+++ + G+ D + ++E
Sbjct: 74 EDYMVEIDILASCD--HPNIVKLLDAFYYENNLWILIEFCAGGAV-DAVMLELERPLTES 130
Query: 502 ACAIVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKL 681
+V + L AL YLH IHR ++A ++L +G +L+ +A QR+
Sbjct: 131 QIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR--- 187
Query: 682 HLLXXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
D W++PEV+ + YD ++D+ G+
Sbjct: 188 ------DSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGI 223
>AL358612-2|CAH73815.1| 197|Homo sapiens myosin IIIA protein.
Length = 197
Score = 56.0 bits (129), Expect = 1e-07
Identities = 46/165 (27%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Frame = +1
Query: 184 PDIND-YQLTSIITECSDGGAVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRK 360
PD +D +++T I + + G V+ L K N K A+K +D + I+ + K
Sbjct: 15 PDPSDTWEITETIGKGTYGK--VFKVLNKKNGQKAAVK--ILDPIHDIDEEIEAEYNILK 70
Query: 361 ELH-HANILPYLASF-----VHGRELYVVSPLMSFGSCRDILDRYFPEG--ISELACAIV 516
L H N++ + + V+G +L++V L S GS D++ + G +SE A +
Sbjct: 71 ALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYI 130
Query: 517 LRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASM 651
L + L LQ+LH IHR V+ +++L+ G +L +A +
Sbjct: 131 LHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL 175
>BX538345-1|CAD98108.1| 1582|Homo sapiens hypothetical protein
protein.
Length = 1582
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/159 (25%), Positives = 70/159 (44%), Gaps = 9/159 (5%)
Frame = +1
Query: 349 LTRKELHHANILPYLASFV------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACA 510
L RK H NI+ + +F +L++V L + GS D++ + + E A
Sbjct: 96 LLRKYSFHKNIVSFYGAFFKLSPPGQRHQLWMVMELCAAGSVTDVVRMTSNQSLKEGWIA 155
Query: 511 IVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLL 690
+ R++LQ L +LH IHR ++ +VL+ N +L +A + R+
Sbjct: 156 YICREILQGLAHLHAHRVIHRDIKGQNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSF--- 212
Query: 691 XXXDHDNANLMWLSPEVL---EQNLKGYDERSDITPSGV 798
W++PEV+ E + YD RSD+ G+
Sbjct: 213 ------IGTPYWMAPEVIDCDEDPRRSYDYRSDVWSVGI 245
>AY834276-1|AAV97884.1| 1042|Homo sapiens mitogen-activated protein
kinase kinase kinase kinase 4 isoform protein.
Length = 1042
Score = 55.2 bits (127), Expect = 3e-07
Identities = 38/139 (27%), Positives = 67/139 (48%), Gaps = 10/139 (7%)
Frame = +1
Query: 238 GAVVYSALYKPNNTKV----AIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFV 405
G Y +YK + K AIK V +E+ ++ ++L +K HH NI Y +F+
Sbjct: 32 GNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINML-KKYSHHRNIATYYGAFI 90
Query: 406 ------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYI 567
H +L++V GS D+++ + E A + R++L+ L +LH I
Sbjct: 91 KKSPPGHDDQLWLVMEFCGAGSITDLVENTKGNTLKEDWIAYISREILRGLAHLHIHHVI 150
Query: 568 HRSVRASHVLIGANGVARL 624
HR +++ +VL+ N +L
Sbjct: 151 HRDIKSQNVLLTENAEVKL 169
>CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein.
Length = 306
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 91 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 149
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 150 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 205
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 206 -----YMSPERIHEN--GYNFKSDIWSLGCL 229
>CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein.
Length = 306
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 91 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 149
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 150 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 205
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 206 -----YMSPERIHEN--GYNFKSDIWSLGCL 229
>BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 212
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 213 -----YMSPERIHEN--GYNFKSDIWSLGCL 236
>BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 212
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 213 -----YMSPERIHEN--GYNFKSDIWSLGCL 236
>BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 212
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 213 -----YMSPERIHEN--GYNFKSDIWSLGCL 236
>BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein.
Length = 313
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 212
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 213 -----YMSPERIHEN--GYNFKSDIWSLGCL 236
>AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 212
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 213 -----YMSPERIHEN--GYNFKSDIWSLGCL 236
>AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 347
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 132 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 190
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 191 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 246
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 247 -----YMSPERIHEN--GYNFKSDIWSLGCL 270
>AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 313
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 98 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 156
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 157 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 212
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 213 -----YMSPERIHEN--GYNFKSDIWSLGCL 236
>AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 347
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 132 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 190
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 191 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 246
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 247 -----YMSPERIHEN--GYNFKSDIWSLGCL 270
>AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6
protein.
Length = 338
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 123 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 181
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 182 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 237
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 238 -----YMSPERIHEN--GYNFKSDIWSLGCL 261
>AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-1512
protein.
Length = 306
Score = 54.4 bits (125), Expect = 5e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
K+L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 91 KQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 149
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 150 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 205
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 206 -----YMSPERIHEN--GYNFKSDIWSLGCL 229
>D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein.
Length = 626
Score = 54.0 bits (124), Expect = 6e-07
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 5/159 (3%)
Frame = +1
Query: 340 QDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVL 519
++V L H NIL ++ VH +L+ ++ M+ G+ +L PE +S +
Sbjct: 99 REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSS--PEPLSWPVRLHLA 156
Query: 520 RDVLQALQYLHKQLYIHRSVRASHVLI-----GANGVARLSGLRTAASMMVRGQRQRKLH 684
D+ + L+YLH + HR + + + L+ G V GL + G R+ L
Sbjct: 157 LDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLA 216
Query: 685 LLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++ + W++PEVL L YDE++D+ G++
Sbjct: 217 VV-------GSPYWMAPEVLRGEL--YDEKADVFAFGIV 246
>BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 54.0 bits (124), Expect = 6e-07
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 5/159 (3%)
Frame = +1
Query: 340 QDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVL 519
++V L H NIL ++ VH +L+ ++ M+ G+ +L PE +S +
Sbjct: 99 REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSS--PEPLSWPVRLHLA 156
Query: 520 RDVLQALQYLHKQLYIHRSVRASHVLI-----GANGVARLSGLRTAASMMVRGQRQRKLH 684
D+ + L+YLH + HR + + + L+ G V GL + G R+ L
Sbjct: 157 LDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLA 216
Query: 685 LLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++ + W++PEVL L YDE++D+ G++
Sbjct: 217 VV-------GSPYWMAPEVLRGEL--YDEKADVFAFGIV 246
>BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 54.0 bits (124), Expect = 6e-07
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 5/159 (3%)
Frame = +1
Query: 340 QDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVL 519
++V L H NIL ++ VH +L+ ++ M+ G+ +L PE +S +
Sbjct: 99 REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSS--PEPLSWPVRLHLA 156
Query: 520 RDVLQALQYLHKQLYIHRSVRASHVLI-----GANGVARLSGLRTAASMMVRGQRQRKLH 684
D+ + L+YLH + HR + + + L+ G V GL + G R+ L
Sbjct: 157 LDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLA 216
Query: 685 LLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++ + W++PEVL L YDE++D+ G++
Sbjct: 217 VV-------GSPYWMAPEVLRGEL--YDEKADVFAFGIV 246
>AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase 1
protein.
Length = 626
Score = 54.0 bits (124), Expect = 6e-07
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 5/159 (3%)
Frame = +1
Query: 340 QDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVL 519
++V L H NIL ++ VH +L+ ++ M+ G+ +L PE +S +
Sbjct: 99 REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSS--PEPLSWPVRLHLA 156
Query: 520 RDVLQALQYLHKQLYIHRSVRASHVLI-----GANGVARLSGLRTAASMMVRGQRQRKLH 684
D+ + L+YLH + HR + + + L+ G V GL + G R+ L
Sbjct: 157 LDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLA 216
Query: 685 LLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++ + W++PEVL L YDE++D+ G++
Sbjct: 217 VV-------GSPYWMAPEVLRGEL--YDEKADVFAFGIV 246
>AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-1
protein.
Length = 244
Score = 53.6 bits (123), Expect = 8e-07
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 5/159 (3%)
Frame = +1
Query: 340 QDVLTRKELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVL 519
++V L H NIL ++ VH +L+ ++ M+ G+ +L PE +S +
Sbjct: 15 REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEXLLSS--PEPLSWPVRLHLA 72
Query: 520 RDVLQALQYLHKQLYIHRSVRASHVLI-----GANGVARLSGLRTAASMMVRGQRQRKLH 684
D+ + L+YLH + HR + + + L+ G V GL + G R+ L
Sbjct: 73 LDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLA 132
Query: 685 LLXXXDHDNANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++ + W++PEVL L YDE++D+ G++
Sbjct: 133 VV-------GSPYWMAPEVLRGEL--YDEKADVFAFGIV 162
>AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein.
Length = 898
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
VY A N VAIK+ Y + EK I ++V ++L H N + Y ++
Sbjct: 38 VYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTA 97
Query: 421 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
++V GS D+L+ + + + E+ A + L L YLH IHR ++A ++L+
Sbjct: 98 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALHGLTYLHSHALIHRDIKAGNILL 155
Query: 601 GANGVARLSGLRTAA 645
G +L+ +A+
Sbjct: 156 TEPGQVKLADFGSAS 170
>AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase
protein.
Length = 898
Score = 53.6 bits (123), Expect = 8e-07
Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
VY A N VAIK+ Y + EK I ++V ++L H N + Y ++
Sbjct: 38 VYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCYLKEHTA 97
Query: 421 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
++V GS D+L+ + + + E+ A + L L YLH IHR ++A ++L+
Sbjct: 98 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILL 155
Query: 601 GANGVARLSGLRTAA 645
G +L+ +A+
Sbjct: 156 TEPGQVKLADFGSAS 170
>BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein.
Length = 1001
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
VY A N VAIK+ Y + EK I ++V + + H N + Y ++
Sbjct: 42 VYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTA 101
Query: 421 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
++V GS D+L+ + + + E+ A + LQ L YLH IHR ++A ++L+
Sbjct: 102 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILL 159
Query: 601 GANGVARLSGLRTAA 645
G +L+ +A+
Sbjct: 160 TEPGQVKLADFGSAS 174
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 52.8 bits (121), Expect = 1e-06
Identities = 47/192 (24%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V A K TK AIK+ ++ G L++++V K + H +I+ F +++
Sbjct: 129 IVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKM 188
Query: 421 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHV-- 594
Y+V L G ++ILDR SE +++ + A+ YLH +HR ++ ++
Sbjct: 189 YLVMELCEDGELKEILDR--KGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMV 246
Query: 595 ---LIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGY 765
LI N L+ T + V+ Q + + L ++++PEV+ + Y
Sbjct: 247 KSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATC----GTPIYMAPEVISAH--DY 300
Query: 766 DERSDITPSGVL 801
++ DI GV+
Sbjct: 301 SQQCDIWSIGVV 312
>AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase
TAO1 protein.
Length = 1001
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
VY A N VAIK+ Y + EK I ++V + + H N + Y ++
Sbjct: 42 VYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTA 101
Query: 421 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
++V GS D+L+ + + + E+ A + LQ L YLH IHR ++A ++L+
Sbjct: 102 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILL 159
Query: 601 GANGVARLSGLRTAA 645
G +L+ +A+
Sbjct: 160 TEPGQVKLADFGSAS 174
>AL162724-8|CAH70253.1| 201|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 201
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
++L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 30 QQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 88
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 89 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 144
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 145 -----YMSPERIHEN--GYNFKSDIWSLGCL 168
>AL137846-12|CAI10882.1| 201|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 6 protein.
Length = 201
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 3/151 (1%)
Frame = +1
Query: 358 KELHHANILPYLASFVHGRELYVVSPLMSFGSCRDILDRYFPEG---ISELACAIVLRDV 528
++L+H NI+ YL SF+ EL +V L G ++ +YF + I E +
Sbjct: 30 QQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMI-KYFKKQKRLIPERTVWKYFVQL 88
Query: 529 LQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHD 708
A++++H + +HR ++ ++V I A GV +L L H L +
Sbjct: 89 CSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFF---SSETTAAHSLVGTPY- 144
Query: 709 NANLMWLSPEVLEQNLKGYDERSDITPSGVL 801
++SPE + +N GY+ +SDI G L
Sbjct: 145 -----YMSPERIHEN--GYNFKSDIWSLGCL 168
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 52.8 bits (121), Expect = 1e-06
Identities = 47/192 (24%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V A K TK AIK+ ++ G L++++V K + H +I+ F +++
Sbjct: 129 IVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKM 188
Query: 421 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHV-- 594
Y+V L G ++ILDR SE +++ + A+ YLH +HR ++ ++
Sbjct: 189 YLVMELCEDGELKEILDR--KGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMV 246
Query: 595 ---LIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGY 765
LI N L+ T + V+ Q + + L ++++PEV+ + Y
Sbjct: 247 KSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATC----GTPIYMAPEVISAH--DY 300
Query: 766 DERSDITPSGVL 801
++ DI GV+
Sbjct: 301 SQQCDIWSIGVV 312
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 52.8 bits (121), Expect = 1e-06
Identities = 47/192 (24%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Frame = +1
Query: 244 VVYSALYKPNNTKVAIKRYFVDR-GKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V A K TK AIK+ ++ G L++++V K + H +I+ F +++
Sbjct: 129 IVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKM 188
Query: 421 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHV-- 594
Y+V L G ++ILDR SE +++ + A+ YLH +HR ++ ++
Sbjct: 189 YLVMELCEDGELKEILDR--KGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMV 246
Query: 595 ---LIGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGY 765
LI N L+ T + V+ Q + + L ++++PEV+ + Y
Sbjct: 247 KSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATC----GTPIYMAPEVISAH--DY 300
Query: 766 DERSDITPSGVL 801
++ DI GV+
Sbjct: 301 SQQCDIWSIGVV 312
>AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein.
Length = 1001
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
VY A N VAIK+ Y + EK I ++V + + H N + Y ++
Sbjct: 42 VYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTA 101
Query: 421 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
++V GS D+L+ + + + E+ A + LQ L YLH IHR ++A ++L+
Sbjct: 102 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILL 159
Query: 601 GANGVARLSGLRTAA 645
G +L+ +A+
Sbjct: 160 TEPGQVKLADFGSAS 174
>AC005035-1|AAY14969.1| 1260|Homo sapiens unknown protein.
Length = 1260
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/160 (25%), Positives = 72/160 (45%), Gaps = 10/160 (6%)
Frame = +1
Query: 349 LTRKELHHANILPYLASFV------HGRELYVVSPLMSFGSCRDILDRYFPEGISELACA 510
+ +K HH NI Y +F+ H +L++V GS D++ + E A
Sbjct: 12 MLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIA 71
Query: 511 IVLRDVLQALQYLHKQLYIHRSVRASHVLIGANGVARLSGLRTAASM-MVRGQRQRKLHL 687
+ R++L+ L +LH IHR ++ +VL+ N +L +A + G+R +
Sbjct: 72 YISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFI-- 129
Query: 688 LXXXDHDNANLMWLSPEVL--EQNLKG-YDERSDITPSGV 798
W++PEV+ ++N YD RSD+ G+
Sbjct: 130 --------GTPYWMAPEVIACDENPDATYDYRSDLWSCGI 161
>AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein.
Length = 1005
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Frame = +1
Query: 247 VYSALYKPNNTKVAIKR--YFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
VY A N VAIK+ Y + EK I ++V + + H N + Y ++
Sbjct: 46 VYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTA 105
Query: 421 YVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVLI 600
++V GS D+L+ + + + E+ A + LQ L YLH IHR ++A ++L+
Sbjct: 106 WLVMEYC-LGSASDLLEVH-KKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILL 163
Query: 601 GANGVARLSGLRTAA 645
G +L+ +A+
Sbjct: 164 TEPGQVKLADFGSAS 178
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 52.4 bits (120), Expect = 2e-06
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 241 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 421 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 597
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 598 IGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+ +R + R L+ N +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTAN----FVAPEVLKR--QGYDAAC 599
Query: 778 DITPSGVL 801
DI GVL
Sbjct: 600 DIWSLGVL 607
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 52.4 bits (120), Expect = 2e-06
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 241 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 421 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 597
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 598 IGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+ +R + R L+ N +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTAN----FVAPEVLKR--QGYDAAC 599
Query: 778 DITPSGVL 801
DI GVL
Sbjct: 600 DIWSLGVL 607
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 52.4 bits (120), Expect = 2e-06
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 241 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 421 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 597
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 598 IGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+ +R + R L+ N +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTAN----FVAPEVLKR--QGYDAAC 599
Query: 778 DITPSGVL 801
DI GVL
Sbjct: 600 DIWSLGVL 607
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 52.4 bits (120), Expect = 2e-06
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 241 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 421 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 597
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 598 IGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+ +R + R L+ N +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTAN----FVAPEVLKR--QGYDAAC 599
Query: 778 DITPSGVL 801
DI GVL
Sbjct: 600 DIWSLGVL 607
>BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 52.4 bits (120), Expect = 2e-06
Identities = 41/140 (29%), Positives = 64/140 (45%), Gaps = 4/140 (2%)
Frame = +1
Query: 241 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTR----KELHHANILPYLASFVH 408
A VY A K N VAIK+ + E I + L +EL H NI+ L +F H
Sbjct: 24 ATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGH 83
Query: 409 GRELYVVSPLMSFGSCRDILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRAS 588
+ +V M I D S + +++ LQ L+YLH+ +HR ++ +
Sbjct: 84 KSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM--TLQGLEYLHRHWILHRDLKPN 141
Query: 589 HVLIGANGVARLSGLRTAAS 648
++L+ NGV +L+ A S
Sbjct: 142 NLLLDENGVLKLADFGLAKS 161
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 52.4 bits (120), Expect = 2e-06
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 241 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 421 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 597
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 598 IGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+ +R + R L+ N +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTAN----FVAPEVLKR--QGYDAAC 599
Query: 778 DITPSGVL 801
DI GVL
Sbjct: 600 DIWSLGVL 607
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 52.4 bits (120), Expect = 2e-06
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 241 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 434 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 489
Query: 421 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 597
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 490 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 546
Query: 598 IGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+ +R + R L+ N +++PEVL++ +GYD
Sbjct: 547 Y-VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTAN----FVAPEVLKR--QGYDAAC 599
Query: 778 DITPSGVL 801
DI GVL
Sbjct: 600 DIWSLGVL 607
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 3 variant protein.
Length = 806
Score = 52.4 bits (120), Expect = 2e-06
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 241 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 500 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 555
Query: 421 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 597
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 556 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 612
Query: 598 IGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+ +R + R L+ N +++PEVL++ +GYD
Sbjct: 613 Y-VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTAN----FVAPEVLKR--QGYDAAC 665
Query: 778 DITPSGVL 801
DI GVL
Sbjct: 666 DIWSLGVL 673
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 52.4 bits (120), Expect = 2e-06
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 1/188 (0%)
Frame = +1
Query: 241 AVVYSALYKPNNTKVAIKRYFVDRGKEKATLIQQDVLTRKELHHANILPYLASFVHGREL 420
+V ++K N + A+K +D+ K T + ++L R H NI+ + G+ +
Sbjct: 420 SVCKRCIHKATNMEFAVK--IIDKSKRDPTE-EIEILLRYG-QHPNIITLKDVYDDGKYV 475
Query: 421 YVVSPLMSFGSCRD-ILDRYFPEGISELACAIVLRDVLQALQYLHKQLYIHRSVRASHVL 597
YVV+ LM G D IL + F SE + VL + + ++YLH Q +HR ++ S++L
Sbjct: 476 YVVTELMKGGELLDKILRQKF---FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNIL 532
Query: 598 IGANGVARLSGLRTAASMMVRGQRQRKLHLLXXXDHDNANLMWLSPEVLEQNLKGYDERS 777
+ +R + R L+ N +++PEVL++ +GYD
Sbjct: 533 Y-VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTAN----FVAPEVLKR--QGYDAAC 585
Query: 778 DITPSGVL 801
DI GVL
Sbjct: 586 DIWSLGVL 593
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 118,111,317
Number of Sequences: 237096
Number of extensions: 2735756
Number of successful extensions: 10957
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 10026
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10605
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9869080686
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -