Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP14_FL5_H01
(886 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 75 5e-13
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 73 2e-12
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 73 2e-12
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 73 2e-12
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 73 2e-12
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 73 2e-12
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 73 2e-12
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 69 2e-11
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 69 2e-11
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 69 2e-11
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 69 2e-11
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 69 3e-11
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 68 5e-11
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 68 5e-11
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 68 5e-11
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 68 5e-11
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 68 5e-11
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 68 5e-11
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 68 5e-11
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 68 5e-11
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 65 3e-10
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 65 3e-10
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 65 3e-10
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 65 3e-10
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 65 3e-10
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 65 3e-10
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 65 3e-10
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 65 3e-10
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 65 3e-10
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 65 3e-10
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 65 3e-10
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 65 3e-10
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 65 3e-10
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 64 5e-10
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 64 5e-10
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 64 5e-10
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 64 5e-10
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 64 5e-10
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 64 9e-10
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 64 9e-10
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 64 9e-10
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 64 9e-10
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 64 9e-10
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 64 9e-10
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 64 9e-10
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 64 9e-10
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 64 9e-10
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 64 9e-10
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 64 9e-10
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 64 9e-10
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 64 9e-10
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 64 9e-10
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 64 9e-10
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 64 9e-10
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 63 1e-09
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 62 2e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 62 2e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 61 5e-09
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 61 6e-09
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 61 6e-09
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 58 3e-08
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 58 3e-08
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 58 4e-08
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 58 4e-08
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 58 4e-08
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 58 4e-08
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 58 4e-08
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 58 6e-08
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 58 6e-08
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 58 6e-08
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 58 6e-08
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 58 6e-08
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 58 6e-08
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 57 7e-08
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 57 1e-07
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 57 1e-07
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 57 1e-07
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 57 1e-07
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 57 1e-07
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 57 1e-07
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 56 2e-07
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 56 2e-07
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 56 2e-07
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 56 2e-07
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 56 2e-07
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 56 2e-07
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 56 2e-07
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 56 2e-07
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 56 2e-07
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 56 2e-07
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 56 2e-07
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 56 2e-07
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 54 7e-07
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 54 7e-07
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 54 7e-07
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 54 7e-07
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 54 7e-07
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 54 7e-07
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 54 9e-07
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 54 9e-07
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 54 9e-07
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 54 9e-07
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 54 9e-07
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 54 9e-07
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 54 9e-07
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 54 9e-07
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 54 9e-07
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 54 9e-07
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 52 2e-06
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 52 2e-06
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 51 5e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 51 5e-06
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 51 6e-06
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 50 8e-06
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 50 8e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 50 8e-06
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 50 8e-06
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 49 2e-05
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 49 2e-05
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 49 2e-05
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 48 3e-05
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 48 3e-05
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 48 3e-05
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 48 3e-05
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 48 3e-05
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 48 5e-05
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 48 5e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 48 6e-05
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 48 6e-05
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 48 6e-05
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 48 6e-05
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 47 8e-05
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 47 8e-05
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 47 8e-05
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 47 8e-05
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 47 8e-05
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 46 2e-04
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 44 6e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 44 6e-04
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 44 6e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 44 6e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 44 6e-04
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 44 6e-04
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 44 6e-04
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 44 7e-04
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 44 7e-04
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 44 7e-04
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 44 7e-04
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 43 0.001
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 43 0.001
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 42 0.002
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 42 0.002
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 41 0.005
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 41 0.005
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 41 0.005
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 41 0.005
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 41 0.005
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 40 0.012
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 39 0.028
BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein. 38 0.048
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 7.3
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 7.3
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 7.3
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 7.3
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 7.3
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 74.5 bits (175), Expect = 5e-13
Identities = 52/192 (27%), Positives = 86/192 (44%), Gaps = 11/192 (5%)
Frame = +2
Query: 62 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 220
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 221 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 397
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 398 VSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXM-- 571
V +NGSV W+ + +++ +P D CT KF S ++ E+D V+ M
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDD 193
Query: 572 -FXSGAWDVTDL 604
SG WD+ L
Sbjct: 194 FTPSGEWDIVAL 205
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 72.5 bits (170), Expect = 2e-12
Identities = 53/193 (27%), Positives = 87/193 (45%), Gaps = 12/193 (6%)
Frame = +2
Query: 62 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 220
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 221 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 395 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXM- 571
V +NGSV W+ + +++ +P D CT KF S ++ E+D V+ M
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 572 --FXSGAWDVTDL 604
SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 72.5 bits (170), Expect = 2e-12
Identities = 53/193 (27%), Positives = 87/193 (45%), Gaps = 12/193 (6%)
Frame = +2
Query: 62 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 220
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 221 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 395 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXM- 571
V +NGSV W+ + +++ +P D CT KF S ++ E+D V+ M
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 572 --FXSGAWDVTDL 604
SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 72.5 bits (170), Expect = 2e-12
Identities = 53/193 (27%), Positives = 87/193 (45%), Gaps = 12/193 (6%)
Frame = +2
Query: 62 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 220
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 221 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 395 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXM- 571
V +NGSV W+ + +++ +P D CT KF S ++ E+D V+ M
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 572 --FXSGAWDVTDL 604
SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 72.5 bits (170), Expect = 2e-12
Identities = 53/193 (27%), Positives = 87/193 (45%), Gaps = 12/193 (6%)
Frame = +2
Query: 62 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 220
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 221 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 395 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXM- 571
V +NGSV W+ + +++ +P D CT KF S ++ E+D V+ M
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 572 --FXSGAWDVTDL 604
SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 72.5 bits (170), Expect = 2e-12
Identities = 53/193 (27%), Positives = 87/193 (45%), Gaps = 12/193 (6%)
Frame = +2
Query: 62 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 220
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 221 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 395 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXM- 571
V +NGSV W+ + +++ +P D CT KF S ++ E+D V+ M
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 572 --FXSGAWDVTDL 604
SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 72.5 bits (170), Expect = 2e-12
Identities = 53/193 (27%), Positives = 87/193 (45%), Gaps = 12/193 (6%)
Frame = +2
Query: 62 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 220
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 221 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 395 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXM- 571
V +NGSV W+ + +++ +P D CT KF S ++ E+D V+ M
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMD 193
Query: 572 --FXSGAWDVTDL 604
SG WD+ L
Sbjct: 194 DFTPSGEWDIVAL 206
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 68.9 bits (161), Expect = 2e-11
Identities = 42/173 (24%), Positives = 82/173 (47%), Gaps = 11/173 (6%)
Frame = +2
Query: 110 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 274
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 275 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 451
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 452 ISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-----IDKRIYXMFXSGAWDV 595
++ + +P D+ C+ KFGS ++ ++D + +DKR + F +G W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDF--FDNGEWEI 220
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 68.9 bits (161), Expect = 2e-11
Identities = 42/173 (24%), Positives = 82/173 (47%), Gaps = 11/173 (6%)
Frame = +2
Query: 110 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 274
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 275 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 451
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 452 ISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-----IDKRIYXMFXSGAWDV 595
++ + +P D+ C+ KFGS ++ ++D + +DKR + F +G W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDF--FDNGEWEI 220
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 68.9 bits (161), Expect = 2e-11
Identities = 42/173 (24%), Positives = 82/173 (47%), Gaps = 11/173 (6%)
Frame = +2
Query: 110 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 274
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 275 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 451
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 452 ISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-----IDKRIYXMFXSGAWDV 595
++ + +P D+ C+ KFGS ++ ++D + +DKR + F +G W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDF--FDNGEWEI 220
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 68.9 bits (161), Expect = 2e-11
Identities = 42/173 (24%), Positives = 82/173 (47%), Gaps = 11/173 (6%)
Frame = +2
Query: 110 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 274
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 275 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 451
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 452 ISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-----IDKRIYXMFXSGAWDV 595
++ + +P D+ C+ KFGS ++ ++D + +DKR + F +G W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDF--FDNGEWEI 220
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 68.5 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = +2
Query: 164 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 337
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 338 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
D+VL N A T V +NGSV W+ + +++ +P D CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 515 RMHNSDEMDFVIDKRIYXM---FXSGAWDVTDL 604
++ E+D V+ M SG WD+ L
Sbjct: 127 WTYDHTEIDMVLMTPTASMDDFTPSGEWDIVAL 159
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 67.7 bits (158), Expect = 5e-11
Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGA 586
V W + +M + +P D C+ KFGS ++ +D + I++ + F +G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 587 WDV 595
W++
Sbjct: 201 WEI 203
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 67.7 bits (158), Expect = 5e-11
Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGA 586
V W + +M + +P D C+ KFGS ++ +D + I++ + F +G
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 165
Query: 587 WDV 595
W++
Sbjct: 166 WEI 168
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 67.7 bits (158), Expect = 5e-11
Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGA 586
V W + +M + +P D C+ KFGS ++ +D + I++ + F +G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 587 WDV 595
W++
Sbjct: 201 WEI 203
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 67.7 bits (158), Expect = 5e-11
Identities = 42/173 (24%), Positives = 81/173 (46%), Gaps = 11/173 (6%)
Frame = +2
Query: 110 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 274
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 275 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 451
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 452 ISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-----IDKRIYXMFXSGAWDV 595
++ + +P D+ C+ KFGS ++ ++D + +DKR + F +G W++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDF--FDNGEWEI 220
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 67.7 bits (158), Expect = 5e-11
Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGA 586
V W + +M + +P D C+ KFGS ++ +D + I++ + F +G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 587 WDV 595
W++
Sbjct: 201 WEI 203
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 67.7 bits (158), Expect = 5e-11
Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGA 586
V W + +M + +P D C+ KFGS ++ +D + I++ + F +G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 587 WDV 595
W++
Sbjct: 201 WEI 203
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 67.7 bits (158), Expect = 5e-11
Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGA 586
V W + +M + +P D C+ KFGS ++ +D + I++ + F +G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 587 WDV 595
W++
Sbjct: 201 WEI 203
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 67.7 bits (158), Expect = 5e-11
Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGA 586
V W + +M + +P D C+ KFGS ++ +D + I++ + F +G
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGE 200
Query: 587 WDV 595
W++
Sbjct: 201 WEI 203
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 204
Query: 587 WDV 595
W +
Sbjct: 205 WAI 207
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 175
Query: 587 WDV 595
W +
Sbjct: 176 WAI 178
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 587 WDV 595
W +
Sbjct: 206 WAI 208
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 204
Query: 587 WDV 595
W +
Sbjct: 205 WAI 207
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 587 WDV 595
W +
Sbjct: 207 WAI 209
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 587 WDV 595
W +
Sbjct: 207 WAI 209
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 587 WDV 595
W +
Sbjct: 206 WAI 208
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 587 WDV 595
W +
Sbjct: 207 WAI 209
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 587 WDV 595
W +
Sbjct: 207 WAI 209
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 587 WDV 595
W +
Sbjct: 207 WAI 209
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 206
Query: 587 WDV 595
W +
Sbjct: 207 WAI 209
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 205
Query: 587 WDV 595
W +
Sbjct: 206 WAI 208
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 65.3 bits (152), Expect = 3e-10
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFXSGA 586
V+WI + + + +P D CT KFGS ++ ++D V+ + + SG
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGE 200
Query: 587 WDV 595
W +
Sbjct: 201 WAI 203
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 64.5 bits (150), Expect = 5e-10
Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 13/188 (6%)
Frame = +2
Query: 83 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 247
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 248 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 412
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD-FVIDKRI--YXMFXSG 583
++W + M + +P D C+ KFGS ++ E+D +I ++ + +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 584 AWDVTDLS 607
W++ D S
Sbjct: 205 EWEIIDAS 212
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 64.5 bits (150), Expect = 5e-10
Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 13/188 (6%)
Frame = +2
Query: 83 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 247
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 248 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 412
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD-FVIDKRI--YXMFXSG 583
++W + M + +P D C+ KFGS ++ E+D +I ++ + +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 584 AWDVTDLS 607
W++ D S
Sbjct: 205 EWEIIDAS 212
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 64.5 bits (150), Expect = 5e-10
Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 13/188 (6%)
Frame = +2
Query: 83 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 247
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 248 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 412
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD-FVIDKRI--YXMFXSG 583
++W + M + +P D C+ KFGS ++ E+D +I ++ + +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 584 AWDVTDLS 607
W++ D S
Sbjct: 205 EWEIIDAS 212
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 64.5 bits (150), Expect = 5e-10
Identities = 51/195 (26%), Positives = 84/195 (43%), Gaps = 7/195 (3%)
Frame = +2
Query: 41 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-NIRES 214
+ L C+ A+ E L+ S R + S++V V L + L ++ E
Sbjct: 14 FGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHER 73
Query: 215 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 388
E + L W D RL+W E+ + S+ +W PDVVL N A +
Sbjct: 74 EQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYS 133
Query: 389 RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYX 568
A VS +GS+ W+ + +++ ++P D CT KF S ++ E+D V+ +
Sbjct: 134 NAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVAS 193
Query: 569 M---FXSGAWDVTDL 604
+ SG WD+ L
Sbjct: 194 LDDFTPSGEWDIVAL 208
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 64.5 bits (150), Expect = 5e-10
Identities = 45/188 (23%), Positives = 86/188 (45%), Gaps = 13/188 (6%)
Frame = +2
Query: 83 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 247
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 248 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 412
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD-FVIDKRI--YXMFXSG 583
++W + M + +P D C+ KFGS ++ E+D +I ++ + +
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENS 204
Query: 584 AWDVTDLS 607
W++ D S
Sbjct: 205 EWEIIDAS 212
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 63.7 bits (148), Expect = 9e-10
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNS-----DEMDFVIDKRIYXMFXS 580
V W+ + S+ + +P D C KFGS ++ ++M+ +D + Y + S
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WES 228
Query: 581 GAWDVTD 601
G W + +
Sbjct: 229 GEWAIVN 235
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 63.7 bits (148), Expect = 9e-10
Identities = 47/177 (26%), Positives = 88/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 110 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 274
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 275 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 439
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 440 ISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGAWDVTD 601
+ S+ + +P D CT KFGS ++ ++D V + R+ + SG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 63.7 bits (148), Expect = 9e-10
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 164 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 337
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 338 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 515 RMHNSDEMDFVIDKRIYXM---FXSGAWDVTDL 604
++ E+D V+ + + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 63.7 bits (148), Expect = 9e-10
Identities = 47/177 (26%), Positives = 88/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 110 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 274
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 275 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 439
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 440 ISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGAWDVTD 601
+ S+ + +P D CT KFGS ++ ++D V + R+ + SG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 63.7 bits (148), Expect = 9e-10
Identities = 47/177 (26%), Positives = 88/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 110 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 274
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 275 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 439
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 440 ISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGAWDVTD 601
+ S+ + +P D CT KFGS ++ ++D V + R+ + SG W + D
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 188
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 63.7 bits (148), Expect = 9e-10
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 164 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 337
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 338 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 515 RMHNSDEMDFVIDKRIYXM---FXSGAWDVTDL 604
++ E+D V+ + + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 63.7 bits (148), Expect = 9e-10
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 164 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 337
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 338 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 515 RMHNSDEMDFVIDKRIYXM---FXSGAWDVTDL 604
++ E+D V+ + + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 63.7 bits (148), Expect = 9e-10
Identities = 47/177 (26%), Positives = 88/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 110 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 274
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 275 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 439
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 440 ISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGAWDVTD 601
+ S+ + +P D CT KFGS ++ ++D V + R+ + SG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 63.7 bits (148), Expect = 9e-10
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 415
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNS-----DEMDFVIDKRIYXMFXS 580
V W+ + S+ + +P D C KFGS ++ ++M+ +D + Y + S
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDY--WES 228
Query: 581 GAWDVTD 601
G W + +
Sbjct: 229 GEWAIVN 235
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 63.7 bits (148), Expect = 9e-10
Identities = 47/177 (26%), Positives = 88/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 110 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 274
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 275 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 439
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 440 ISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGAWDVTD 601
+ S+ + +P D CT KFGS ++ ++D V + R+ + SG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 63.7 bits (148), Expect = 9e-10
Identities = 47/177 (26%), Positives = 88/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 110 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 274
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 275 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 439
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 440 ISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGAWDVTD 601
+ S+ + +P D CT KFGS ++ ++D V + R+ + SG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 63.7 bits (148), Expect = 9e-10
Identities = 47/177 (26%), Positives = 88/177 (49%), Gaps = 13/177 (7%)
Frame = +2
Query: 110 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 274
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 275 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 439
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 440 ISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV-IDKRI--YXMFXSGAWDVTD 601
+ S+ + +P D CT KFGS ++ ++D V + R+ + SG W + D
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 213
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 63.7 bits (148), Expect = 9e-10
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 164 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 337
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 338 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 515 RMHNSDEMDFVIDKRIYXM---FXSGAWDVTDL 604
++ E+D V+ + + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 63.7 bits (148), Expect = 9e-10
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 164 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 337
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 338 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 515 RMHNSDEMDFVIDKRIYXM---FXSGAWDVTDL 604
++ E+D V+ + + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 63.7 bits (148), Expect = 9e-10
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 164 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 337
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 338 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 515 RMHNSDEMDFVIDKRIYXM---FXSGAWDVTDL 604
++ E+D V+ + + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 63.7 bits (148), Expect = 9e-10
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 164 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 337
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 338 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 515 RMHNSDEMDFVIDKRIYXM---FXSGAWDVTDL 604
++ E+D V+ + + SG WD+ L
Sbjct: 176 WTYDRTEIDLVLKSEVASLDDFTPSGEWDIVAL 208
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/126 (27%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 406
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNAV---GDFQVTTKTKALLKY 140
Query: 407 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVI---DKRIYXMFX 577
G V+WI + + + +P D CT KFGS ++ ++D V+ + +
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWE 200
Query: 578 SGAWDV 595
SG W +
Sbjct: 201 SGEWAI 206
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 62.5 bits (145), Expect = 2e-09
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 4/137 (2%)
Frame = +2
Query: 140 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 313
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 314 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 487
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 488 XTCTFKFGSRMHNSDEM 538
CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 62.5 bits (145), Expect = 2e-09
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 4/137 (2%)
Frame = +2
Query: 140 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 313
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 314 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 487
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 488 XTCTFKFGSRMHNSDEM 538
CT F S ++S E+
Sbjct: 163 QNCTMVFSSYSYDSSEV 179
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 61.3 bits (142), Expect = 5e-09
Identities = 44/139 (31%), Positives = 70/139 (50%), Gaps = 6/139 (4%)
Frame = +2
Query: 140 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 313
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 314 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPN 481
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 482 DMXTCTFKFGSRMHNSDEM 538
D CT F S ++S E+
Sbjct: 161 DWQNCTMVFSSYSYDSSEV 179
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 60.9 bits (141), Expect = 6e-09
Identities = 35/134 (26%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +2
Query: 152 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 325
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 326 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTF 502
+W P++VL N G Y V GSV+W+ + ++++ +P D C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 503 KFGSRMHNSDEMDF 544
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 60.9 bits (141), Expect = 6e-09
Identities = 35/134 (26%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +2
Query: 152 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 325
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 326 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTF 502
+W P++VL N G Y V GSV+W+ + ++++ +P D C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 503 KFGSRMHNSDEMDF 544
F S+ +N++E++F
Sbjct: 165 IFRSQTYNAEEVEF 178
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 8/157 (5%)
Frame = +2
Query: 110 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 274
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 275 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 445
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 446 TPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDK 556
+ S+ + +P D C+ F S+ ++++E+D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 8/157 (5%)
Frame = +2
Query: 110 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 274
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 275 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARV--SNNGSVSWIKRLDIS 445
W+ ++ G V S +WRPD+VL N + AL V S +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVF-EVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 446 TPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDK 556
+ S+ + +P D C+ F S+ ++++E+D + +
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQ 187
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/180 (23%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Frame = +2
Query: 32 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 196
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 197 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 364
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 365 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
+ + + +G ++W + + + +P D C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/180 (23%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Frame = +2
Query: 32 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 196
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 197 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 364
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 365 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
+ + + +G ++W + + + +P D C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/180 (23%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Frame = +2
Query: 32 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 196
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 197 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 364
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 365 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
+ + + +G ++W + + + +P D C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/180 (23%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Frame = +2
Query: 32 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 196
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 197 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 364
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 365 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
+ + + +G ++W + + + +P D C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/180 (23%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Frame = +2
Query: 32 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 196
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 197 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 364
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 365 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
+ + + +G ++W + + + +P D C FGS +N +++D
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 57.6 bits (133), Expect = 6e-08
Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 418
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 419 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXMFXSGAWDVT 598
+ K + + + ++ + +P D CT F S ++ D M ++K + W++T
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WEIT 202
Query: 599 DLS 607
D S
Sbjct: 203 DAS 205
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 57.6 bits (133), Expect = 6e-08
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 1/123 (0%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 418
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 419 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXMFXSGAWDVT 598
+ K + +++ ++ + +P D CTF F S ++ D M +DK + W++T
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV--------WEIT 202
Query: 599 DLS 607
D S
Sbjct: 203 DTS 205
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 57.6 bits (133), Expect = 6e-08
Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 418
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 419 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXMFXSGAWDVT 598
+ K + + + ++ + +P D CT F S ++ D M ++K + W++T
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WEIT 131
Query: 599 DLS 607
D S
Sbjct: 132 DAS 134
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 57.6 bits (133), Expect = 6e-08
Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 418
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 419 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXMFXSGAWDVT 598
+ K + + + ++ + +P D CT F S ++ D M ++K + W++T
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WEIT 217
Query: 599 DLS 607
D S
Sbjct: 218 DAS 220
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 57.6 bits (133), Expect = 6e-08
Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 418
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 419 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXMFXSGAWDVT 598
+ K + + + ++ + +P D CT F S ++ D M ++K + W++T
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WEIT 217
Query: 599 DLS 607
D S
Sbjct: 218 DAS 220
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 57.6 bits (133), Expect = 6e-08
Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 418
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 419 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXMFXSGAWDVT 598
+ K + + + ++ + +P D CT F S ++ D M ++K + W++T
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WEIT 217
Query: 599 DLS 607
D S
Sbjct: 218 DAS 220
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 57.2 bits (132), Expect = 7e-08
Identities = 31/123 (25%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 418
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 419 SWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXMFXSGAWDVT 598
+ K + +++ + + +P D CTF F S ++ D M +DK + W++T
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEV--------WEIT 202
Query: 599 DLS 607
D S
Sbjct: 203 DTS 205
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/168 (25%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 41 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 205
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 206 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 382
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 383 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
A+ + + G ++W + + + ++P D C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/168 (25%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 41 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 205
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 206 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 382
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 383 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
A+ + + G ++W + + + ++P D C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/168 (25%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 41 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 205
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 206 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 382
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 383 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
A+ + + G ++W + + + ++P D C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/168 (25%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 41 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 205
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 206 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 382
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 383 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
A+ + + G ++W + + + ++P D C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 56.8 bits (131), Expect = 1e-07
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +2
Query: 74 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 241
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 242 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 412
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
++W + + + +P D C FGS +N +++D
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 56.8 bits (131), Expect = 1e-07
Identities = 42/168 (25%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Frame = +2
Query: 41 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 205
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 206 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 382
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 383 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGS 514
A+ + + G ++W + + + ++P D C+ K G+
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 77 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 241
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 242 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 406
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 407 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
+G+V W + + + +P D C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 77 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 241
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 242 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 406
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 407 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
+G+V W + + + +P D C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 77 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 241
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 242 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 406
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 407 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
+G+V W + + + +P D C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/165 (26%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Frame = +2
Query: 77 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 241
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 242 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 406
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 407 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
+G+V W + + + +P D C FGS H ++D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 55.6 bits (128), Expect = 2e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 29 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 190
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 191 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 367
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 368 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
++ R+ +G+V + R+ + M L +P D CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 539 DF 544
+F
Sbjct: 189 EF 190
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 55.6 bits (128), Expect = 2e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 29 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 190
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 191 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 367
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 368 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
++ R+ +G+V + R+ + M L +P D CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 539 DF 544
+F
Sbjct: 189 EF 190
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 55.6 bits (128), Expect = 2e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 29 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 190
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 191 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 367
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 368 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
++ R+ +G+V + R+ + M L +P D CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 539 DF 544
+F
Sbjct: 189 EF 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 55.6 bits (128), Expect = 2e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 29 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 190
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 191 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 367
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 368 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
++ R+ +G+V + R+ + M L +P D CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 539 DF 544
+F
Sbjct: 189 EF 190
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 55.6 bits (128), Expect = 2e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 29 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 190
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 191 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 367
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 368 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
++ R+ +G+V + R+ + M L +P D CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 539 DF 544
+F
Sbjct: 189 EF 190
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 55.6 bits (128), Expect = 2e-07
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 10/182 (5%)
Frame = +2
Query: 29 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 190
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 191 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 367
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 368 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
++ R+ +G+V + R+ + M L +P D CT + S + +D++
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 188
Query: 539 DF 544
+F
Sbjct: 189 EF 190
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 1/125 (0%)
Frame = +2
Query: 236 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 412
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXMFXSGAWD 592
+ + K + + + ++ + +P D CT F S ++ D M ++K + W+
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WE 200
Query: 593 VTDLS 607
+TD S
Sbjct: 201 ITDAS 205
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 1/125 (0%)
Frame = +2
Query: 236 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 412
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKRIYXMFXSGAWD 592
+ + K + + + ++ + +P D CT F S ++ D M ++K + W+
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEV--------WE 185
Query: 593 VTDLS 607
+TD S
Sbjct: 186 ITDAS 190
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 54.0 bits (124), Expect = 7e-07
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 134 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 295
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 296 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 472
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 473 WPNDMXTCTFKFGSRMHNSDEM 538
+P D C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 54.0 bits (124), Expect = 7e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 421
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 422 WIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 54.0 bits (124), Expect = 7e-07
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 134 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 295
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 296 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 472
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 473 WPNDMXTCTFKFGSRMHNSDEM 538
+P D C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 54.0 bits (124), Expect = 7e-07
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 134 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 295
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 296 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 472
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 473 WPNDMXTCTFKFGSRMHNSDEM 538
+P D C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 54.0 bits (124), Expect = 7e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 421
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 422 WIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 54.0 bits (124), Expect = 7e-07
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 134 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 295
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 296 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 472
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 473 WPNDMXTCTFKFGSRMHNSDEM 538
+P D C+ KF S + + E+
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEI 179
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 53.6 bits (123), Expect = 9e-07
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 415
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKR-IYXMFXSGAWD 592
++ + + + +P D+ C KFGS + +D + + I +G WD
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 174
Query: 593 VTDL 604
+ +
Sbjct: 175 LVGI 178
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 53.6 bits (123), Expect = 9e-07
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 415
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKR-IYXMFXSGAWD 592
++ + + + +P D+ C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 593 VTDL 604
+ +
Sbjct: 198 LVGI 201
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 53.6 bits (123), Expect = 9e-07
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 415
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKR-IYXMFXSGAWD 592
++ + + + +P D+ C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 593 VTDL 604
+ +
Sbjct: 198 LVGI 201
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 53.6 bits (123), Expect = 9e-07
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 415
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKR-IYXMFXSGAWD 592
++ + + + +P D+ C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 593 VTDL 604
+ +
Sbjct: 198 LVGI 201
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 53.6 bits (123), Expect = 9e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +2
Query: 86 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 253
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 254 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 424
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 425 IKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV 547
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 53.6 bits (123), Expect = 9e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +2
Query: 86 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 253
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 254 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 424
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 425 IKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV 547
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 53.6 bits (123), Expect = 9e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +2
Query: 86 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 253
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 254 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 424
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 425 IKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV 547
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 53.6 bits (123), Expect = 9e-07
Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 7/161 (4%)
Frame = +2
Query: 86 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 253
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 254 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 424
W D+RL + + + ++W PD N + A + R+ ++G++ +
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 425 IKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFV 547
RL IS MQL+++P D C KFGS + + E+ +V
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYV 204
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 53.6 bits (123), Expect = 9e-07
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 415
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKR-IYXMFXSGAWD 592
++ + + + +P D+ C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 593 VTDL 604
+ +
Sbjct: 198 LVGI 201
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/101 (27%), Positives = 49/101 (48%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 421
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 422 WIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
L T + +L ++P D C+ F + + + E++F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEF 186
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 3/124 (2%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 415
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKR-IYXMFXSGAWD 592
++ + + + +P D+ C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 593 VTDL 604
+ +
Sbjct: 198 LVGI 201
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 3/124 (2%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 415
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 416 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDKR-IYXMFXSGAWD 592
++ + + + +P D+ C KFGS + +D + + I +G WD
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWD 197
Query: 593 VTDL 604
+ +
Sbjct: 198 LVGI 201
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 51.2 bits (117), Expect = 5e-06
Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 7/171 (4%)
Frame = +2
Query: 53 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 220
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 221 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 391
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 392 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
R+ +G+V + R+ + M L +P D CT + S + +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 51.2 bits (117), Expect = 5e-06
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 7/133 (5%)
Frame = +2
Query: 50 LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RES 214
LL A+ A+ N L+ D L+ YD P + VVN++L L N+ E
Sbjct: 11 LLLLAVCLGAQGRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNER 68
Query: 215 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYAL 388
E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + + L
Sbjct: 69 EEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDL 128
Query: 389 RARVSNNGSVSWI 427
+ + S+ WI
Sbjct: 129 QLSQEDGQSIEWI 141
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 50.8 bits (116), Expect = 6e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 86 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 253
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 254 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 424
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 425 IKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 50.4 bits (115), Expect = 8e-06
Identities = 39/171 (22%), Positives = 72/171 (42%), Gaps = 7/171 (4%)
Frame = +2
Query: 53 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 220
+ C S E N + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 221 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 391
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 392 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
R+ +G+V + R+ + M L +P D CT + S + +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 86 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 253
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 254 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 424
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 425 IKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 242 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 421
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 422 WIKRLDISTPISMQLDNWPNDMXTCTFKF 508
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 7/158 (4%)
Frame = +2
Query: 86 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 253
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 254 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSW 424
W D+RL ++ + + ++W PD N + A + R+ +NG++ +
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 425 IKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
RL I M L+++P D+ C KFGS + + E+
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEV 219
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 49.2 bits (112), Expect = 2e-05
Identities = 37/155 (23%), Positives = 68/155 (43%), Gaps = 7/155 (4%)
Frame = +2
Query: 95 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 262
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 263 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 433
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 434 LDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
L I+ +QL N+P D +C F S + +EM
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 49.2 bits (112), Expect = 2e-05
Identities = 37/155 (23%), Positives = 68/155 (43%), Gaps = 7/155 (4%)
Frame = +2
Query: 95 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 262
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 263 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 433
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 434 LDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
L I+ +QL N+P D +C F S + +EM
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 49.2 bits (112), Expect = 2e-05
Identities = 37/155 (23%), Positives = 68/155 (43%), Gaps = 7/155 (4%)
Frame = +2
Query: 95 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 262
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 263 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 433
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 434 LDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
L I+ +QL N+P D +C F S + +EM
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 181
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 7/160 (4%)
Frame = +2
Query: 98 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 265
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 266 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 436
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 437 DISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDK 556
I+ M+L N+P D C KFGS + E+ + K
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKK 190
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 7/160 (4%)
Frame = +2
Query: 98 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 265
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 266 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 436
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 437 DISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDK 556
I+ M+L N+P D C KFGS + E+ + K
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKK 190
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 7/160 (4%)
Frame = +2
Query: 98 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 265
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 266 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 436
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 437 DISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDK 556
I+ M+L N+P D C KFGS + E+ + K
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKK 190
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 7/160 (4%)
Frame = +2
Query: 98 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 265
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 266 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 436
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 437 DISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDK 556
I+ M+L N+P D C KFGS + E+ + K
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKK 190
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 7/160 (4%)
Frame = +2
Query: 98 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 265
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 266 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 436
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 437 DISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDK 556
I+ M+L N+P D C KFGS + E+ + K
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKK 190
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 48.0 bits (109), Expect = 5e-05
Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 3/119 (2%)
Frame = +2
Query: 209 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 388
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 389 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDK 556
R+ NG++ + RL IS M+L ++P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 48.0 bits (109), Expect = 5e-05
Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 3/119 (2%)
Frame = +2
Query: 209 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 388
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 389 RA---RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDFVIDK 556
R+ NG++ + RL IS M+L ++P D C KFGS + EM + K
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTK 206
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 47.6 bits (108), Expect = 6e-05
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 47.6 bits (108), Expect = 6e-05
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 47.6 bits (108), Expect = 6e-05
Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 47.6 bits (108), Expect = 6e-05
Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 1/111 (0%)
Frame = +2
Query: 200 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 376
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 377 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNS 529
+ + G V K L + T S+ + N+P D+ C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TCT + S + +++ F
Sbjct: 178 NFPMDVQTCTMQLESFGYTMNDLIF 202
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 62 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 220
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 221 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 382
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 62 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 220
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 221 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 382
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 7/171 (4%)
Frame = +2
Query: 53 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 220
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 221 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 391
+ Q +W DKRLS++ + +++L PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 392 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
R+ +G+V + R+ + M L +P D CT + S + +D+++F
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 80 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 244
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 245 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 412
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
+V + R+ + +M L +P D TC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 83 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 250
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 251 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 421
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 422 WIKRLDISTPISMQLDNWPNDMXTC 496
+ RL + S+ L +P D C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 83 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 250
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 251 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 421
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 422 WIKRLDISTPISMQLDNWPNDMXTC 496
+ RL + S+ L +P D C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 80 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 244
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 245 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 412
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
+V + R+ + +M L +P D TC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 80 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 244
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 245 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 412
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
+V + R+ + +M L +P D TC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 80 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 244
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 245 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 412
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
+V + R+ + +M L +P D TC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 80 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 244
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 245 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 412
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
+V + R+ + +M L +P D TC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 44.4 bits (100), Expect = 6e-04
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 113 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 280
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 281 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 451
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 452 ISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
M L +P D C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 44.4 bits (100), Expect = 6e-04
Identities = 37/157 (23%), Positives = 70/157 (44%), Gaps = 9/157 (5%)
Frame = +2
Query: 101 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHANIRES---ESTVRILADLQMNWID 262
++ +++SLL YD + PD + V+ +++ + E T+ I+ W D
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDII--FAQTWFD 121
Query: 263 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 433
RL +N+ ++W PD N+ + A R+ N+G V + R
Sbjct: 122 SRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
Query: 434 LDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
L I+ +QL N+P D +C +F S + +E+++
Sbjct: 182 LTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEY 218
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 44.4 bits (100), Expect = 6e-04
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 113 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 280
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 281 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 451
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 452 ISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
M L +P D C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 83 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 250
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 251 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 421
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 422 WIKRLDISTPISMQLDNWPNDMXTC 496
+ RL + S+ L +P D C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 83 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 250
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 251 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 421
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 422 WIKRLDISTPISMQLDNWPNDMXTC 496
+ RL + S+ L +P D C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 44.4 bits (100), Expect = 6e-04
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Frame = +2
Query: 113 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 280
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 281 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 451
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 452 ISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
M L +P D C S ++S+++
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDI 192
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 44.4 bits (100), Expect = 6e-04
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = +2
Query: 80 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 244
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 245 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 412
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 413 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
+V + R+ + +M L +P D TC + S ++ ++++F
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEF 190
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 44.0 bits (99), Expect = 7e-04
Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Frame = +2
Query: 101 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 262
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 263 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 433
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 434 LDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
L I +QL N+P D +C +F S + +E+
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 44.0 bits (99), Expect = 7e-04
Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Frame = +2
Query: 101 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 262
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 263 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 433
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 434 LDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
L I +QL N+P D +C +F S + +E+
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 44.0 bits (99), Expect = 7e-04
Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Frame = +2
Query: 101 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 262
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 263 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 433
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 434 LDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
L I +QL N+P D +C +F S + +E+
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 44.0 bits (99), Expect = 7e-04
Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Frame = +2
Query: 101 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 262
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 263 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 433
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 434 LDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
L I +QL N+P D +C +F S + +E+
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 15/188 (7%)
Frame = +2
Query: 26 LYYSCYXFLLTCAIASAAEC-ENAT---SLSLMIDSLLAT---YDRESPPDSK-IVVNLT 181
LY S + A + AE +AT S S +D L+ YD P+ K VN++
Sbjct: 9 LYLSGAIVFFSLAASKEAEAARSATKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVS 68
Query: 182 LHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVL 349
++ +I E+ R+ L+ W D RL++N S + +W+PD+
Sbjct: 69 CNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFF 128
Query: 350 LNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRM 520
N + R+S NG+V + R+ ++ M L N+P D+ TC + S
Sbjct: 129 ANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFG 188
Query: 521 HNSDEMDF 544
+ +++ F
Sbjct: 189 YTMNDLIF 196
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/155 (24%), Positives = 70/155 (45%), Gaps = 9/155 (5%)
Frame = +2
Query: 101 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 262
+++++++LL YD + PD + +++ +++ N E T+ I QM W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFF-AQM-WYD 123
Query: 263 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 433
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLR 183
Query: 434 LDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEM 538
L I +QL N+P D +C +F S + +E+
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI 218
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +2
Query: 200 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 376
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 377 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
+ R+S NG+V + R+ ++ M L N+P D+ TC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Frame = +2
Query: 200 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 376
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 377 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
+ R+S NG+V + R+ ++ M L N+P D+ TC + S + +++ F
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 196
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 41.1 bits (92), Expect = 0.005
Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 41.1 bits (92), Expect = 0.005
Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TCT + S + ++ F
Sbjct: 137 NFPMDIQTCTMQLESFGYTMKDLVF 161
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Frame = +2
Query: 134 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 301
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 302 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 469
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 470 NWPNDMXTCTFKFGSRMHNSDEMDF 544
N+P D+ TC + S + +++ F
Sbjct: 177 NFPMDVQTCIMQLESFGYTMNDLIF 201
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 39.9 bits (89), Expect = 0.012
Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 4/110 (3%)
Frame = +2
Query: 227 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 394
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 395 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMDF 544
R+S NG+V + R+ ++ M L N+P D+ TC + S + +++ F
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF 113
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 38.7 bits (86), Expect = 0.028
Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Frame = +2
Query: 326 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFK 505
LW +A A + +A + ++G V W + S+ + +P D CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 506 FGSRMHNSDEMDFV-IDKRI--YXMFXSGAWDVTD 601
FGS ++ ++D V + R+ + SG W + D
Sbjct: 85 FGSWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVD 119
>BC096291-1|AAH96291.1| 556|Homo sapiens CHRNA4 protein protein.
Length = 556
Score = 37.9 bits (84), Expect = 0.048
Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Frame = +2
Query: 374 GDYAL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFGSRMHNSDEMD 541
GD+A+ +A + ++G V W + S+ + +P D CT KFGS ++ ++D
Sbjct: 60 GDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKID 119
Query: 542 FV-IDKRI--YXMFXSGAWDVTD 601
V + R+ + SG W + D
Sbjct: 120 LVNMHSRVDQLDFWESGEWVIVD 142
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 7.3
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 275 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 436
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.3
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 275 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 436
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 7.3
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 275 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 436
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.3
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 275 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 436
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 7.3
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 275 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 436
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,734,852
Number of Sequences: 237096
Number of extensions: 2559052
Number of successful extensions: 6782
Number of sequences better than 10.0: 174
Number of HSP's better than 10.0 without gapping: 6035
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6648
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11326166088
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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