Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP13_T7_J07
(803 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y13892-1|CAA74194.1| 1609|Homo sapiens PI-3 kinase protein. 44 6e-04
Y11312-1|CAA72168.1| 1634|Homo sapiens phosphoinositide 3-kinase... 44 6e-04
BC132876-1|AAI32877.1| 1634|Homo sapiens phosphoinositide-3-kina... 44 6e-04
AL606489-4|CAI16572.1| 1634|Homo sapiens phosphoinositide-3-kina... 44 6e-04
AB210006-1|BAE06088.1| 1645|Homo sapiens PIK3C2B variant protein... 44 6e-04
BC130277-1|AAI30278.1| 1444|Homo sapiens phosphoinositide-3-kina... 39 0.018
AJ000008-1|CAA03853.1| 1448|Homo sapiens PI3-kinase protein. 39 0.018
Y13367-1|CAA73797.1| 1686|Homo sapiens phosphoinositide 3-kinase... 39 0.024
BC113658-1|AAI13659.1| 1686|Homo sapiens phosphoinositide-3-kina... 39 0.024
S67334-1|AAB29081.1| 1070|Homo sapiens phosphatidylinositol 3-ki... 38 0.056
BC114432-1|AAI14433.1| 1070|Homo sapiens phosphoinositide-3-kina... 38 0.056
AJ297549-1|CAC21449.1| 1070|Homo sapiens phosphatidylinositol 3-... 38 0.056
Y10055-1|CAA71149.2| 1044|Homo sapiens phosphoinositide 3-kinase... 37 0.074
U86453-1|AAC25677.1| 1044|Homo sapiens phosphatidylinositol 3-ki... 37 0.074
U57843-1|AAB53966.1| 1068|Homo sapiens phosphatidylinositol 3-ki... 37 0.074
DQ263596-1|ABB83816.1| 1044|Homo sapiens phosphoinositide-3-kina... 37 0.074
DQ263595-1|ABB83815.1| 1044|Homo sapiens phosphoinositide-3-kina... 37 0.074
DQ263594-1|ABB83814.1| 1044|Homo sapiens phosphoinositide-3-kina... 37 0.074
BC150297-1|AAI50298.1| 1044|Homo sapiens phosphoinositide-3-kina... 37 0.074
BC132921-1|AAI32922.1| 1044|Homo sapiens phosphoinositide-3-kina... 37 0.074
BC132919-1|AAI32920.1| 1044|Homo sapiens phosphoinositide-3-kina... 37 0.074
AL691449-6|CAI15702.1| 1068|Homo sapiens phosphoinositide-3-kina... 37 0.074
AL691449-5|CAI15703.1| 1044|Homo sapiens phosphoinositide-3-kina... 37 0.074
AB208835-1|BAD92072.1| 845|Homo sapiens phosphoinositide-3-kina... 37 0.074
Z46973-1|CAA87094.1| 887|Homo sapiens phosphatidylinositol 3-ki... 31 6.4
>Y13892-1|CAA74194.1| 1609|Homo sapiens PI-3 kinase protein.
Length = 1609
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/142 (28%), Positives = 56/142 (39%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 397
FPD VR A + + +SD +L LPQL QAL++E Y
Sbjct: 869 FPDQEVRRMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLRVTHY 928
Query: 396 LFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENL 217
FWLL L D+ S ++Y +L ALL CG+ L
Sbjct: 929 FFWLLKDGL-------------------------KDSQFSIRYQY--LLAALLCCCGKGL 961
Query: 216 NKTLLRQQLLVKSLCEMAVSVK 151
+ RQ LV +L ++A V+
Sbjct: 962 REEFNRQCWLVNALAKLAQQVR 983
>Y11312-1|CAA72168.1| 1634|Homo sapiens phosphoinositide 3-kinase
protein.
Length = 1634
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/142 (28%), Positives = 56/142 (39%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 397
FPD VR A + + +SD +L LPQL QAL++E Y
Sbjct: 894 FPDQEVRRMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLRVTHY 953
Query: 396 LFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENL 217
FWLL L D+ S ++Y +L ALL CG+ L
Sbjct: 954 FFWLLKDGL-------------------------KDSQFSIRYQY--LLAALLCCCGKGL 986
Query: 216 NKTLLRQQLLVKSLCEMAVSVK 151
+ RQ LV +L ++A V+
Sbjct: 987 REEFNRQCWLVNALAKLAQQVR 1008
>BC132876-1|AAI32877.1| 1634|Homo sapiens phosphoinositide-3-kinase,
class 2, beta polypeptide protein.
Length = 1634
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/142 (28%), Positives = 56/142 (39%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 397
FPD VR A + + +SD +L LPQL QAL++E Y
Sbjct: 894 FPDQEVRRMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLRVTHY 953
Query: 396 LFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENL 217
FWLL L D+ S ++Y +L ALL CG+ L
Sbjct: 954 FFWLLKDGL-------------------------KDSQFSIRYQY--LLAALLCCCGKGL 986
Query: 216 NKTLLRQQLLVKSLCEMAVSVK 151
+ RQ LV +L ++A V+
Sbjct: 987 REEFNRQCWLVNALAKLAQQVR 1008
>AL606489-4|CAI16572.1| 1634|Homo sapiens phosphoinositide-3-kinase,
class 2, beta polypeptide protein.
Length = 1634
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/142 (28%), Positives = 56/142 (39%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 397
FPD VR A + + +SD +L LPQL QAL++E Y
Sbjct: 894 FPDQEVRRMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLRVTHY 953
Query: 396 LFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENL 217
FWLL L D+ S ++Y +L ALL CG+ L
Sbjct: 954 FFWLLKDGL-------------------------KDSQFSIRYQY--LLAALLCCCGKGL 986
Query: 216 NKTLLRQQLLVKSLCEMAVSVK 151
+ RQ LV +L ++A V+
Sbjct: 987 REEFNRQCWLVNALAKLAQQVR 1008
>AB210006-1|BAE06088.1| 1645|Homo sapiens PIK3C2B variant protein
protein.
Length = 1645
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/142 (28%), Positives = 56/142 (39%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 397
FPD VR A + + +SD +L LPQL QAL++E Y
Sbjct: 905 FPDQEVRRMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLRVTHY 964
Query: 396 LFWLLVHSLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGENL 217
FWLL L D+ S ++Y +L ALL CG+ L
Sbjct: 965 FFWLLKDGL-------------------------KDSQFSIRYQY--LLAALLCCCGKGL 997
Query: 216 NKTLLRQQLLVKSLCEMAVSVK 151
+ RQ LV +L ++A V+
Sbjct: 998 REEFNRQCWLVNALAKLAQQVR 1019
>BC130277-1|AAI30278.1| 1444|Homo sapiens phosphoinositide-3-kinase,
class 2, gamma polypeptide protein.
Length = 1444
Score = 39.1 bits (87), Expect = 0.018
Identities = 44/147 (29%), Positives = 68/147 (46%), Gaps = 1/147 (0%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 397
FPD +R+ A + L+ + +D+L LPQL QA++ E
Sbjct: 731 FPDQEIRKVAVQQLDNLLNDELLEYLPQLVQAVKFE------------------WNLESP 772
Query: 396 LFWLLVH-SLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGEN 220
L LL+H SL +I Q H+ + + +NAE +A SW Y +L AL G+
Sbjct: 773 LVQLLLHRSLQSI-QVAHRLYWLL-------KNAENEAYFK-SW-YQKLLAALQFCAGKA 822
Query: 219 LNKTLLRQQLLVKSLCEMAVSVKCAKE 139
LN ++Q L+K L ++ VK A +
Sbjct: 823 LNDEFSKEQKLIKILGDIGERVKSASD 849
>AJ000008-1|CAA03853.1| 1448|Homo sapiens PI3-kinase protein.
Length = 1448
Score = 39.1 bits (87), Expect = 0.018
Identities = 44/147 (29%), Positives = 68/147 (46%), Gaps = 1/147 (0%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 397
FPD +R+ A + L+ + +D+L LPQL QA++ E
Sbjct: 732 FPDQEIRKVAVQQLDNLLNDELLEYLPQLVQAVKFE------------------WNLESP 773
Query: 396 LFWLLVH-SLPNIPQAPHQEFLGINLEDNASENAETDASMSASWRYTLMLRALLVICGEN 220
L LL+H SL +I Q H+ + + +NAE +A SW Y +L AL G+
Sbjct: 774 LVQLLLHRSLQSI-QVAHRLYWLL-------KNAENEAYFK-SW-YQKLLAALQFCAGKA 823
Query: 219 LNKTLLRQQLLVKSLCEMAVSVKCAKE 139
LN ++Q L+K L ++ VK A +
Sbjct: 824 LNDEFSKEQKLIKILGDIGERVKSASD 850
>Y13367-1|CAA73797.1| 1686|Homo sapiens phosphoinositide 3-kinase
protein.
Length = 1686
Score = 38.7 bits (86), Expect = 0.024
Identities = 22/72 (30%), Positives = 32/72 (44%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 397
F D VR A + +SDD+L +LPQ QAL++E Y
Sbjct: 950 FADQEVRSLAVTWIEAISDDELTDLLPQFVQALKYEIYLNSSLVQFLLSRALGNIQIAHN 1009
Query: 396 LFWLLVHSLPNI 361
L+WLL +L ++
Sbjct: 1010 LYWLLKDALHDV 1021
>BC113658-1|AAI13659.1| 1686|Homo sapiens phosphoinositide-3-kinase,
class 2, alpha polypeptide protein.
Length = 1686
Score = 38.7 bits (86), Expect = 0.024
Identities = 22/72 (30%), Positives = 32/72 (44%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETYXXXXXXXXXXXXXXXXXXXXXX 397
F D VR A + +SDD+L +LPQ QAL++E Y
Sbjct: 950 FADQEVRSLAVTWIEAISDDELTDLLPQFVQALKYEIYLNSSLVQFLLSRALGNIQIAHN 1009
Query: 396 LFWLLVHSLPNI 361
L+WLL +L ++
Sbjct: 1010 LYWLLKDALHDV 1021
>S67334-1|AAB29081.1| 1070|Homo sapiens phosphatidylinositol
3-kinase p110 beta isoform protein.
Length = 1070
Score = 37.5 bits (83), Expect = 0.056
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
+PD VRE A L +MSD++L + L QL Q L++E +
Sbjct: 614 YPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPF 651
>BC114432-1|AAI14433.1| 1070|Homo sapiens phosphoinositide-3-kinase,
catalytic, beta polypeptide protein.
Length = 1070
Score = 37.5 bits (83), Expect = 0.056
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
+PD VRE A L +MSD++L + L QL Q L++E +
Sbjct: 614 YPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPF 651
>AJ297549-1|CAC21449.1| 1070|Homo sapiens phosphatidylinositol
3-kinase catalytic subunit p110beta protein.
Length = 1070
Score = 37.5 bits (83), Expect = 0.056
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
+PD VRE A L +MSD++L + L QL Q L++E +
Sbjct: 614 YPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPF 651
>Y10055-1|CAA71149.2| 1044|Homo sapiens phosphoinositide 3-kinase
protein.
Length = 1044
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 587 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 624
>U86453-1|AAC25677.1| 1044|Homo sapiens phosphatidylinositol
3-kinase catalytic subunit p110delta protein.
Length = 1044
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 587 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 624
>U57843-1|AAB53966.1| 1068|Homo sapiens phosphatidylinositol
3-kinase delta catalytic subunit protein.
Length = 1068
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 611 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 648
>DQ263596-1|ABB83816.1| 1044|Homo sapiens phosphoinositide-3-kinase
D protein.
Length = 1044
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 587 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 624
>DQ263595-1|ABB83815.1| 1044|Homo sapiens phosphoinositide-3-kinase
C protein.
Length = 1044
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 587 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 624
>DQ263594-1|ABB83814.1| 1044|Homo sapiens phosphoinositide-3-kinase
B protein.
Length = 1044
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 587 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 624
>BC150297-1|AAI50298.1| 1044|Homo sapiens phosphoinositide-3-kinase,
catalytic, delta polypeptide protein.
Length = 1044
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 587 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 624
>BC132921-1|AAI32922.1| 1044|Homo sapiens phosphoinositide-3-kinase,
catalytic, delta polypeptide protein.
Length = 1044
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 587 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 624
>BC132919-1|AAI32920.1| 1044|Homo sapiens phosphoinositide-3-kinase,
catalytic, delta polypeptide protein.
Length = 1044
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 587 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 624
>AL691449-6|CAI15702.1| 1068|Homo sapiens phosphoinositide-3-kinase,
catalytic, delta polypeptide protein.
Length = 1068
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 611 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 648
>AL691449-5|CAI15703.1| 1044|Homo sapiens phosphoinositide-3-kinase,
catalytic, delta polypeptide protein.
Length = 1044
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 587 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 624
>AB208835-1|BAD92072.1| 845|Homo sapiens phosphoinositide-3-kinase,
catalytic, delta polypeptide variant protein.
Length = 845
Score = 37.1 bits (82), Expect = 0.074
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
FPD V A K L +++DD+L + L QL Q L++E+Y
Sbjct: 388 FPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY 425
>Z46973-1|CAA87094.1| 887|Homo sapiens phosphatidylinositol
3-kinase protein.
Length = 887
Score = 30.7 bits (66), Expect = 6.4
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = -3
Query: 576 FPDVAVRETAAKLLNEMSDDDLCRVLPQLTQALRHETY 463
+ + VR A L + D+DL L QL QAL++E +
Sbjct: 371 YTNPTVRRYAVARLRQADDEDLLMYLSQLVQALKYENF 408
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 77,800,587
Number of Sequences: 237096
Number of extensions: 1119939
Number of successful extensions: 2648
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 2582
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2648
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9924838204
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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