Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP13_T7_E10
(797 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 115 2e-25
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 115 2e-25
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 115 2e-25
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 115 2e-25
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 104 4e-22
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 104 4e-22
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 104 4e-22
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 104 4e-22
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 104 4e-22
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 104 4e-22
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 99 2e-20
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 99 2e-20
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 99 2e-20
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 99 2e-20
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 99 2e-20
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 99 2e-20
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 99 2e-20
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 99 2e-20
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 98 3e-20
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 96 1e-19
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 96 1e-19
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 96 1e-19
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 96 1e-19
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 96 1e-19
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 93 1e-18
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 93 1e-18
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 91 4e-18
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 91 4e-18
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 91 4e-18
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 91 4e-18
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 85 3e-16
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 85 3e-16
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 85 3e-16
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 85 3e-16
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 85 4e-16
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 85 4e-16
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 84 5e-16
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 84 5e-16
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 84 5e-16
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 84 5e-16
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 83 9e-16
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 83 9e-16
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 83 9e-16
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 83 9e-16
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 83 9e-16
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 83 9e-16
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 83 9e-16
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 83 9e-16
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 83 9e-16
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 83 9e-16
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 83 9e-16
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 83 9e-16
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 83 9e-16
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 83 1e-15
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 82 2e-15
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 79 1e-14
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 79 1e-14
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 79 1e-14
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 79 1e-14
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 79 1e-14
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 79 1e-14
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 79 1e-14
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 79 1e-14
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 79 1e-14
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 77 6e-14
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 77 6e-14
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 77 7e-14
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 77 7e-14
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 77 7e-14
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 77 7e-14
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 77 7e-14
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 77 7e-14
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 76 1e-13
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 76 1e-13
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 76 1e-13
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 76 1e-13
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 76 1e-13
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 75 2e-13
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 75 4e-13
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 74 7e-13
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 74 7e-13
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 74 7e-13
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 74 7e-13
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 74 7e-13
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 74 7e-13
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 74 7e-13
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 73 2e-12
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 73 2e-12
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 72 2e-12
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 72 2e-12
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 72 2e-12
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 72 2e-12
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 72 2e-12
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 72 2e-12
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 72 2e-12
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 72 2e-12
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 72 2e-12
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 72 2e-12
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 72 3e-12
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 72 3e-12
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 72 3e-12
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 72 3e-12
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 72 3e-12
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 72 3e-12
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 72 3e-12
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 72 3e-12
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 72 3e-12
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 72 3e-12
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 71 4e-12
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 71 4e-12
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 71 4e-12
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 71 4e-12
BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family... 71 4e-12
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 71 5e-12
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 71 5e-12
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 71 5e-12
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 71 5e-12
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 71 5e-12
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 71 5e-12
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 71 6e-12
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 71 6e-12
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 71 6e-12
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 71 6e-12
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 71 6e-12
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 71 6e-12
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 71 6e-12
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 71 6e-12
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 71 6e-12
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 71 6e-12
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 71 6e-12
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 71 6e-12
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 71 6e-12
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 70 9e-12
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 70 9e-12
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 70 1e-11
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 70 1e-11
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 67 6e-11
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 67 6e-11
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 67 6e-11
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 67 6e-11
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 67 6e-11
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 65 2e-10
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 65 3e-10
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 65 3e-10
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 65 3e-10
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 65 3e-10
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 65 3e-10
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 63 1e-09
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 63 1e-09
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 62 2e-09
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 62 3e-09
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 62 3e-09
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 60 9e-09
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 60 9e-09
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 60 9e-09
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 60 9e-09
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 60 9e-09
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 60 9e-09
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 60 9e-09
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 60 9e-09
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 60 9e-09
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 60 9e-09
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 60 9e-09
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 60 9e-09
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 60 9e-09
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 60 9e-09
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 60 9e-09
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 60 9e-09
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 60 9e-09
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 60 1e-08
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 60 1e-08
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 60 1e-08
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 60 1e-08
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 60 1e-08
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 60 1e-08
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 60 1e-08
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 60 1e-08
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 60 1e-08
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 59 2e-08
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 59 2e-08
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 59 2e-08
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 59 2e-08
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 59 2e-08
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 59 2e-08
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 58 4e-08
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 58 4e-08
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 58 5e-08
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 58 5e-08
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 58 5e-08
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 58 5e-08
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 58 5e-08
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 57 6e-08
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 57 6e-08
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 57 6e-08
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 57 6e-08
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 56 1e-07
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 56 1e-07
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 56 1e-07
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 56 2e-07
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 56 2e-07
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 56 2e-07
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 56 2e-07
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 56 2e-07
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 55 3e-07
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 55 3e-07
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 55 3e-07
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 55 3e-07
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 55 3e-07
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 55 3e-07
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 55 3e-07
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 55 3e-07
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 55 3e-07
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 54 5e-07
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 54 5e-07
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 54 5e-07
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 53 1e-06
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 52 3e-06
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 51 6e-06
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 51 6e-06
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 50 7e-06
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 49 2e-05
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 49 2e-05
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 49 2e-05
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 49 2e-05
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 48 3e-05
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 48 3e-05
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 48 3e-05
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 48 3e-05
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 48 3e-05
BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 48 3e-05
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 48 3e-05
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 48 3e-05
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 48 3e-05
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 48 3e-05
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 48 3e-05
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 48 3e-05
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 48 3e-05
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 48 3e-05
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 48 3e-05
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 48 3e-05
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 48 3e-05
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 48 3e-05
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 48 3e-05
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 48 3e-05
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 48 3e-05
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 48 3e-05
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 48 3e-05
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 48 4e-05
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 48 4e-05
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 48 4e-05
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 48 4e-05
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 48 5e-05
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 47 9e-05
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 47 9e-05
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 47 9e-05
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 46 1e-04
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 46 1e-04
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 46 1e-04
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 46 1e-04
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 46 1e-04
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 46 1e-04
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 46 1e-04
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 46 1e-04
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 46 2e-04
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 46 2e-04
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 46 2e-04
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 46 2e-04
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 46 2e-04
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 46 2e-04
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 46 2e-04
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 46 2e-04
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 46 2e-04
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 46 2e-04
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 46 2e-04
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 46 2e-04
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 46 2e-04
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 46 2e-04
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 46 2e-04
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 46 2e-04
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 46 2e-04
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 46 2e-04
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 45 3e-04
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 45 3e-04
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 45 3e-04
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 45 3e-04
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 45 3e-04
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 45 3e-04
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 45 4e-04
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 45 4e-04
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 45 4e-04
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 45 4e-04
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 45 4e-04
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 44 5e-04
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 44 5e-04
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 44 6e-04
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 44 6e-04
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 44 6e-04
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 44 6e-04
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 44 6e-04
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 43 0.001
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 43 0.001
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 43 0.001
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 43 0.001
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 43 0.001
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 43 0.001
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 43 0.001
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 43 0.001
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 43 0.001
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 43 0.001
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 42 0.002
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 42 0.002
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 42 0.002
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 42 0.002
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 42 0.002
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 42 0.002
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 42 0.002
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 42 0.002
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 42 0.002
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 42 0.002
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 42 0.002
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 42 0.002
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 42 0.002
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 42 0.002
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 42 0.003
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 41 0.006
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 41 0.006
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 41 0.006
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 40 0.008
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 40 0.010
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 40 0.010
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 40 0.010
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 40 0.010
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 40 0.010
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 40 0.010
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 40 0.010
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 40 0.010
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 40 0.014
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 39 0.024
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 38 0.032
AC011737-1|AAX88915.1| 382|Homo sapiens unknown protein. 38 0.042
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 38 0.055
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 36 0.13
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 35 0.30
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 35 0.30
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 35 0.30
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 35 0.30
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 35 0.30
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 35 0.30
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 35 0.30
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 35 0.30
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 35 0.30
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 35 0.30
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 35 0.39
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 34 0.52
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 33 0.90
BC070050-1|AAH70050.1| 1022|Homo sapiens SRRM2 protein protein. 33 0.90
AF201422-1|AAF21439.1| 2296|Homo sapiens splicing coactivator su... 33 0.90
AB016092-1|BAA83718.1| 2752|Homo sapiens RNA binding protein pro... 33 0.90
AB016088-1|BAA83714.1| 956|Homo sapiens RNA binding protein pro... 33 0.90
AB016087-1|BAA83713.1| 1262|Homo sapiens RNA binding protein pro... 33 0.90
AB002322-1|BAA20782.3| 2800|Homo sapiens KIAA0324 protein protein. 33 0.90
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 33 1.6
AC005336-2|AAC27731.1| 93|Homo sapiens F20191_1, partial CDS p... 32 2.1
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 32 2.8
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 31 3.6
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 31 3.6
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 31 3.6
X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase ... 31 3.6
X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 31 3.6
BC146803-1|AAI46804.1| 371|Homo sapiens SLC15A4 protein protein. 31 3.6
BC012476-1|AAH12476.2| 468|Homo sapiens hypothetical protein LO... 31 3.6
AY358212-1|AAQ88579.1| 468|Homo sapiens PPWG6510 protein. 31 3.6
AK125861-1|BAC86325.1| 367|Homo sapiens protein ( Homo sapiens ... 31 3.6
AK123780-1|BAC85690.1| 367|Homo sapiens protein ( Homo sapiens ... 31 3.6
AK074159-1|BAB84985.1| 318|Homo sapiens FLJ00232 protein protein. 31 3.6
AK127300-1|BAC86924.1| 207|Homo sapiens A3). protein. 31 4.8
AK123815-1|BAC85700.1| 138|Homo sapiens protein ( Homo sapiens ... 31 4.8
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 115 bits (277), Expect = 2e-25
Identities = 70/204 (34%), Positives = 115/204 (56%), Gaps = 5/204 (2%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A + ++L ++G + +Q K+ +E RP T DL LRY
Sbjct: 322 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 381
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
E + ETLRLFP P R +D +++ + V +GT + + R R + P+ E
Sbjct: 382 ECVIKETLRLFPSVPLFARSVSEDCEVAGYR--VLKGTEAVIIPYALHRDPRYF-PNPEE 438
Query: 276 YRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRE--LEFTAEQA 112
++PER+ P +AQ P A++ FS G R CIG+ +A+ KT+L+ +R +E ++
Sbjct: 439 FQPERFF-PENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKRE 497
Query: 111 ELQLKLDVVLRPASGHLLQVKTRN 40
EL L+ ++LRP++G +++K RN
Sbjct: 498 ELGLEGQLILRPSNGIWIKLKRRN 521
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 115 bits (277), Expect = 2e-25
Identities = 70/204 (34%), Positives = 115/204 (56%), Gaps = 5/204 (2%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A + ++L ++G + +Q K+ +E RP T DL LRY
Sbjct: 322 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 381
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
E + ETLRLFP P R +D +++ + V +GT + + R R + P+ E
Sbjct: 382 ECVIKETLRLFPSVPLFARSVSEDCEVAGYR--VLKGTEAVIIPYALHRDPRYF-PNPEE 438
Query: 276 YRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRE--LEFTAEQA 112
++PER+ P +AQ P A++ FS G R CIG+ +A+ KT+L+ +R +E ++
Sbjct: 439 FQPERFF-PENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKRE 497
Query: 111 ELQLKLDVVLRPASGHLLQVKTRN 40
EL L+ ++LRP++G +++K RN
Sbjct: 498 ELGLEGQLILRPSNGIWIKLKRRN 521
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 115 bits (277), Expect = 2e-25
Identities = 70/204 (34%), Positives = 115/204 (56%), Gaps = 5/204 (2%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A + ++L ++G + +Q K+ +E RP T DL LRY
Sbjct: 300 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 359
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
E + ETLRLFP P R +D +++ + V +GT + + R R + P+ E
Sbjct: 360 ECVIKETLRLFPSVPLFARSVSEDCEVAGYR--VLKGTEAVIIPYALHRDPRYF-PNPEE 416
Query: 276 YRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRE--LEFTAEQA 112
++PER+ P +AQ P A++ FS G R CIG+ +A+ KT+L+ +R +E ++
Sbjct: 417 FQPERFF-PENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKRE 475
Query: 111 ELQLKLDVVLRPASGHLLQVKTRN 40
EL L+ ++LRP++G +++K RN
Sbjct: 476 ELGLEGQLILRPSNGIWIKLKRRN 499
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 115 bits (277), Expect = 2e-25
Identities = 70/204 (34%), Positives = 115/204 (56%), Gaps = 5/204 (2%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A + ++L ++G + +Q K+ +E RP T DL LRY
Sbjct: 322 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 381
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
E + ETLRLFP P R +D +++ + V +GT + + R R + P+ E
Sbjct: 382 ECVIKETLRLFPSVPLFARSVSEDCEVAGYR--VLKGTEAVIIPYALHRDPRYF-PNPEE 438
Query: 276 YRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRE--LEFTAEQA 112
++PER+ P +AQ P A++ FS G R CIG+ +A+ KT+L+ +R +E ++
Sbjct: 439 FQPERFF-PENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKRE 497
Query: 111 ELQLKLDVVLRPASGHLLQVKTRN 40
EL L+ ++LRP++G +++K RN
Sbjct: 498 ELGLEGQLILRPSNGIWIKLKRRN 521
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 104 bits (249), Expect = 4e-22
Identities = 65/204 (31%), Positives = 103/204 (50%), Gaps = 4/204 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +FG H+T A+ L + L + R Q++ E + DL L +
Sbjct: 321 EADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
V E+LRL PP P + R +D+ L G+ V+P+G C + + + +W PD
Sbjct: 381 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLIDIIGVHHNPTVW-PDPE 438
Query: 279 EYRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
Y P R+ P +++ P AF+ FS G R CIG+ +AMA +K VLA + F + E
Sbjct: 439 VYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTE 497
Query: 108 LQLKLDVVLRPASGHLLQVKTRNL 37
+ KL++++R G L+V+ N+
Sbjct: 498 PRRKLELIMRAEGGLWLRVEPLNV 521
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 104 bits (249), Expect = 4e-22
Identities = 65/204 (31%), Positives = 103/204 (50%), Gaps = 4/204 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +FG H+T A+ L + L + R Q++ E + DL L +
Sbjct: 321 EADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
V E+LRL PP P + R +D+ L G+ V+P+G C + + + +W PD
Sbjct: 381 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLIDIIGVHHNPTVW-PDPE 438
Query: 279 EYRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
Y P R+ P +++ P AF+ FS G R CIG+ +AMA +K VLA + F + E
Sbjct: 439 VYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTE 497
Query: 108 LQLKLDVVLRPASGHLLQVKTRNL 37
+ KL++++R G L+V+ N+
Sbjct: 498 PRRKLELIMRAEGGLWLRVEPLNV 521
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 104 bits (249), Expect = 4e-22
Identities = 65/204 (31%), Positives = 103/204 (50%), Gaps = 4/204 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +FG H+T A+ L + L + R Q++ E + DL L +
Sbjct: 321 EADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
V E+LRL PP P + R +D+ L G+ V+P+G C + + + +W PD
Sbjct: 381 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLIDIIGVHHNPTVW-PDPE 438
Query: 279 EYRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
Y P R+ P +++ P AF+ FS G R CIG+ +AMA +K VLA + F + E
Sbjct: 439 VYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTE 497
Query: 108 LQLKLDVVLRPASGHLLQVKTRNL 37
+ KL++++R G L+V+ N+
Sbjct: 498 PRRKLELIMRAEGGLWLRVEPLNV 521
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 104 bits (249), Expect = 4e-22
Identities = 65/204 (31%), Positives = 103/204 (50%), Gaps = 4/204 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +FG H+T A+ L + L + R Q++ E + DL L +
Sbjct: 255 EADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPF 314
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
V E+LRL PP P + R +D+ L G+ V+P+G C + + + +W PD
Sbjct: 315 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLIDIIGVHHNPTVW-PDPE 372
Query: 279 EYRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
Y P R+ P +++ P AF+ FS G R CIG+ +AMA +K VLA + F + E
Sbjct: 373 VYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTE 431
Query: 108 LQLKLDVVLRPASGHLLQVKTRNL 37
+ KL++++R G L+V+ N+
Sbjct: 432 PRRKLELIMRAEGGLWLRVEPLNV 455
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 104 bits (249), Expect = 4e-22
Identities = 65/204 (31%), Positives = 103/204 (50%), Gaps = 4/204 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +FG H+T A+ L + L + R Q++ E + DL L +
Sbjct: 321 EADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
V E+LRL PP P + R +D+ L G+ V+P+G C + + + +W PD
Sbjct: 381 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLIDIIGVHHNPTVW-PDPE 438
Query: 279 EYRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
Y P R+ P +++ P AF+ FS G R CIG+ +AMA +K VLA + F + E
Sbjct: 439 VYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTE 497
Query: 108 LQLKLDVVLRPASGHLLQVKTRNL 37
+ KL++++R G L+V+ N+
Sbjct: 498 PRRKLELIMRAEGGLWLRVEPLNV 521
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 104 bits (249), Expect = 4e-22
Identities = 65/204 (31%), Positives = 103/204 (50%), Gaps = 4/204 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +FG H+T A+ L + L + R Q++ E + DL L +
Sbjct: 321 EADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
V E+LRL PP P + R +D+ L G+ V+P+G C + + + +W PD
Sbjct: 381 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGR-VIPKGITCLIDIIGVHHNPTVW-PDPE 438
Query: 279 EYRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
Y P R+ P +++ P AF+ FS G R CIG+ +AMA +K VLA + F + E
Sbjct: 439 VYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTE 497
Query: 108 LQLKLDVVLRPASGHLLQVKTRNL 37
+ KL++++R G L+V+ N+
Sbjct: 498 PRRKLELIMRAEGGLWLRVEPLNV 521
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 99.1 bits (236), Expect = 2e-20
Identities = 62/199 (31%), Positives = 95/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL HL +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP P + R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAMW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VLA + + E
Sbjct: 439 VYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 99.1 bits (236), Expect = 2e-20
Identities = 62/199 (31%), Positives = 95/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL HL +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP P + R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAMW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VLA + + E
Sbjct: 439 VYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 98.7 bits (235), Expect = 2e-20
Identities = 62/199 (31%), Positives = 95/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL HL +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP P + R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VLA + + E
Sbjct: 439 VYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 98.7 bits (235), Expect = 2e-20
Identities = 62/199 (31%), Positives = 95/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL HL +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP P + R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VLA + + E
Sbjct: 439 VYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 98.7 bits (235), Expect = 2e-20
Identities = 62/199 (31%), Positives = 95/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL HL +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP P + R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VLA + + E
Sbjct: 439 VYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 98.7 bits (235), Expect = 2e-20
Identities = 62/199 (31%), Positives = 95/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL HL +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP P + R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VLA + + E
Sbjct: 439 VYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 98.7 bits (235), Expect = 2e-20
Identities = 64/200 (32%), Positives = 97/200 (48%), Gaps = 4/200 (2%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +FG H+T A+ L + L + R Q++ E + DL L +
Sbjct: 321 EADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP P R +D+ L + V+P+G VC ++ + +W PD
Sbjct: 381 LTMCLKESLRLHPPIPTFARGCTQDVVLPDSR-VIPKGNVCNINIFAIHHNPSVW-PDPE 438
Query: 279 EYRPERWLAPPHAQ---PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
Y P R+ P +AQ P AF+ FS G R CIG+ +AMA +K VLA + + E
Sbjct: 439 VYDPFRF-DPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHRE 497
Query: 108 LQLKLDVVLRPASGHLLQVK 49
+ ++VLR G L+V+
Sbjct: 498 PRRTPEIVLRAEDGLWLRVE 517
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 98.7 bits (235), Expect = 2e-20
Identities = 62/199 (31%), Positives = 95/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL HL +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP P + R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VLA + + E
Sbjct: 439 VYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 98.3 bits (234), Expect = 3e-20
Identities = 61/199 (30%), Positives = 95/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL HL +
Sbjct: 321 EADTFMFEGHDTTASVLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LR+ PP P + R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCMKESLRVHPPVPVISRHVTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VLA + + E
Sbjct: 439 VYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 96.3 bits (229), Expect = 1e-19
Identities = 62/199 (31%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL L +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP PAV R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VL + + E
Sbjct: 439 VYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 96.3 bits (229), Expect = 1e-19
Identities = 62/199 (31%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL L +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP PAV R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VL + + E
Sbjct: 439 VYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGIWLRVE 517
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 95.9 bits (228), Expect = 1e-19
Identities = 62/199 (31%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL L +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP PAV R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VL + + E
Sbjct: 439 VYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 95.9 bits (228), Expect = 1e-19
Identities = 62/199 (31%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL L +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP PAV R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VL + + E
Sbjct: 439 VYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 95.9 bits (228), Expect = 1e-19
Identities = 62/199 (31%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL L +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP PAV R +D+ L G+ V+P+G +C +S +W PD
Sbjct: 381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGR-VIPKGIICLISVFGTHHNPAVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VL + + E
Sbjct: 439 VYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K ++VLR G L+V+
Sbjct: 499 RRKPELVLRAEGGLWLRVE 517
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 93.1 bits (221), Expect = 1e-18
Identities = 60/199 (30%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXR-PVTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL L +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP P + R +D L G+ V+P+G VC ++ + + +W PD
Sbjct: 381 LTMCIKESLRLHPPVPVISRCCTQDFVLPDGR-VIPKGIVCLINIIGIHYNPTVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VLA + E
Sbjct: 439 VYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K +++LR G L+V+
Sbjct: 499 RRKPELILRAEGGLWLRVE 517
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 92.7 bits (220), Expect = 1e-18
Identities = 60/199 (30%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXR-PVTGADLPHLRY 460
E DT +F H+T A+ L + L + + Q++ E + DL L +
Sbjct: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPF 380
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LRL PP P + R +D L G+ V+P+G VC ++ + + +W PD
Sbjct: 381 LTMCIKESLRLHPPVPVISRCCTQDFVLPDGR-VIPKGIVCLINIIGIHYNPTVW-PDPE 438
Query: 279 EYRPERWLAP--PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAEL 106
Y P R+ P AF+ FS G R CIG+ +AMA +K VLA + E
Sbjct: 439 VYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHIEP 498
Query: 105 QLKLDVVLRPASGHLLQVK 49
+ K +++LR G L+V+
Sbjct: 499 RRKPELILRAEGGLWLRVE 517
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 91.1 bits (216), Expect = 4e-18
Identities = 56/200 (28%), Positives = 101/200 (50%), Gaps = 4/200 (2%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T ++ + + L + + Q+K E + DL L +
Sbjct: 328 EADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPF 387
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LR +PP V R +D++L G+ ++P+G +C VS +W PD+
Sbjct: 388 TTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR-IIPKGIICLVSIYGTHHNPTVW-PDSK 445
Query: 279 EYRPERWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQA-E 109
Y P R+ P P A++ FS G R CIG+++AMA L+ V+A + + ++ +
Sbjct: 446 VYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRK 505
Query: 108 LQLKLDVVLRPASGHLLQVK 49
++ K +++LR +G L+V+
Sbjct: 506 VRRKPELILRTENGLWLKVE 525
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 91.1 bits (216), Expect = 4e-18
Identities = 56/200 (28%), Positives = 101/200 (50%), Gaps = 4/200 (2%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T ++ + + L + + Q+K E + DL L +
Sbjct: 328 EADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPF 387
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LR +PP V R +D++L G+ ++P+G +C VS +W PD+
Sbjct: 388 TTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR-IIPKGIICLVSIYGTHHNPTVW-PDSK 445
Query: 279 EYRPERWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQA-E 109
Y P R+ P P A++ FS G R CIG+++AMA L+ V+A + + ++ +
Sbjct: 446 VYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRK 505
Query: 108 LQLKLDVVLRPASGHLLQVK 49
++ K +++LR +G L+V+
Sbjct: 506 VRRKPELILRTENGLWLKVE 525
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 91.1 bits (216), Expect = 4e-18
Identities = 56/200 (28%), Positives = 101/200 (50%), Gaps = 4/200 (2%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T ++ + + L + + Q+K E + DL L +
Sbjct: 328 EADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPF 387
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LR +PP V R +D++L G+ ++P+G +C VS +W PD+
Sbjct: 388 TTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR-IIPKGIICLVSIYGTHHNPTVW-PDSK 445
Query: 279 EYRPERWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQA-E 109
Y P R+ P P A++ FS G R CIG+++AMA L+ V+A + + ++ +
Sbjct: 446 VYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRK 505
Query: 108 LQLKLDVVLRPASGHLLQVK 49
++ K +++LR +G L+V+
Sbjct: 506 VRRKPELILRTENGLWLKVE 525
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 91.1 bits (216), Expect = 4e-18
Identities = 56/200 (28%), Positives = 101/200 (50%), Gaps = 4/200 (2%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP-VTGADLPHLRY 460
E DT +F H+T ++ + + L + + Q+K E + DL L +
Sbjct: 328 EADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPF 387
Query: 459 CEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
+ E+LR +PP V R +D++L G+ ++P+G +C VS +W PD+
Sbjct: 388 TTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR-IIPKGIICLVSIYGTHHNPTVW-PDSK 445
Query: 279 EYRPERWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQA-E 109
Y P R+ P P A++ FS G R CIG+++AMA L+ V+A + + ++ +
Sbjct: 446 VYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRK 505
Query: 108 LQLKLDVVLRPASGHLLQVK 49
++ K +++LR +G L+V+
Sbjct: 506 VRRKPELILRTENGLWLKVE 525
>U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha
demethylase protein.
Length = 503
Score = 85.0 bits (201), Expect = 3e-16
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 2/171 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
+ +L G H T +TT + + RDK LQ K Y E P+T L L +
Sbjct: 306 IGLLLAGQH-TSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLD 364
Query: 453 ATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEY 274
+ ETLRL PP ++RMA + Q +G + P VC VS V R + W + ++
Sbjct: 365 RCIRETLRLRPPIMIMMRMA-RTPQTVAGYTIPPGHQVC-VSPTVNQRLKDSW-VERLDF 421
Query: 273 RPERWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF 127
P+R+L P + A++ F GR CIG+N+A +KT+ ++ +R EF
Sbjct: 422 NPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEF 472
>U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase
cytochrome P450 protein.
Length = 509
Score = 85.0 bits (201), Expect = 3e-16
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 2/171 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
+ +L G H T +TT + + RDK LQ K Y E P+T L L +
Sbjct: 312 IGLLLAGQH-TSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLD 370
Query: 453 ATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEY 274
+ ETLRL PP ++RMA + Q +G + P VC VS V R + W + ++
Sbjct: 371 RCIKETLRLRPPIMIMMRMA-RTPQTVAGYTIPPGHQVC-VSPTVNQRLKDSW-VERLDF 427
Query: 273 RPERWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF 127
P+R+L P + A++ F GR CIG+N+A +KT+ ++ +R EF
Sbjct: 428 NPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEF 478
>D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase
protein.
Length = 509
Score = 85.0 bits (201), Expect = 3e-16
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 2/171 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
+ +L G H T +TT + + RDK LQ K Y E P+T L L +
Sbjct: 312 IGLLLAGQH-TSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLD 370
Query: 453 ATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEY 274
+ ETLRL PP ++RMA + Q +G + P VC VS V R + W + ++
Sbjct: 371 RCIKETLRLRPPIMIMMRMA-RTPQTVAGYTIPPGHQVC-VSPTVNQRLKDSW-VERLDF 427
Query: 273 RPERWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF 127
P+R+L P + A++ F GR CIG+N+A +KT+ ++ +R EF
Sbjct: 428 NPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEF 478
>AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein.
Length = 509
Score = 85.0 bits (201), Expect = 3e-16
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 2/171 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
+ +L G H T +TT + + RDK LQ K Y E P+T L L +
Sbjct: 312 IGLLLAGQH-TSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLD 370
Query: 453 ATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEY 274
+ ETLRL PP ++RMA + Q +G + P VC VS V R + W + ++
Sbjct: 371 RCIKETLRLRPPIMIMMRMA-RTPQTVAGYTIPPGHQVC-VSPTVNQRLKDSW-VERLDF 427
Query: 273 RPERWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF 127
P+R+L P + A++ F GR CIG+N+A +KT+ ++ +R EF
Sbjct: 428 NPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEF 478
>BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family
51, subfamily A, polypeptide 1 protein.
Length = 509
Score = 84.6 bits (200), Expect = 4e-16
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 2/171 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
+ +L G H T +TT + + RDK LQ K Y E P+T L L +
Sbjct: 312 IGLLLAGQH-TSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLD 370
Query: 453 ATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEY 274
+ ETLRL PP ++RMA + Q +G + P VC VS V R + W + ++
Sbjct: 371 RCIKETLRLRPPVMIMMRMA-RTPQTVAGYTIPPGHQVC-VSPTVNQRLKDSW-VERLDF 427
Query: 273 RPERWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF 127
P+R+L P + A++ F GR CIG+N+A +KT+ ++ +R EF
Sbjct: 428 NPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEF 478
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 84.6 bits (200), Expect = 4e-16
Identities = 57/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L I Q + E DL + Y
Sbjct: 308 EVDTFMFEGHDTTTSGISWFLYCIALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 366
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 367 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 424
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 484
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 485 IKMPQLVLRSKNGFHLHLK 503
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 84.2 bits (199), Expect = 5e-16
Identities = 54/167 (32%), Positives = 82/167 (49%), Gaps = 1/167 (0%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET A +L++ L + R+ +Q KL E P DL ++ Y +A + E++RL
Sbjct: 72 ETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVP-RAEDLRNMPYLKACLKESMRL 130
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWLAPP 247
P P R DK L G+ +P+GTV ++ V+G + + D++++RPERWL
Sbjct: 131 TPSVPFTTRTLDKATVL--GEYALPKGTVLMLNTQVLGSSEDNF-EDSSQFRPERWLQEK 187
Query: 246 HA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
P A L F G+R CIG+ A L L VR+ + A E
Sbjct: 188 EKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNE 234
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 84.2 bits (199), Expect = 5e-16
Identities = 54/167 (32%), Positives = 82/167 (49%), Gaps = 1/167 (0%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET A +L++ L + R+ +Q KL E P DL ++ Y +A + E++RL
Sbjct: 187 ETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVP-RAEDLRNMPYLKACLKESMRL 245
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWLAPP 247
P P R DK L G+ +P+GTV ++ V+G + + D++++RPERWL
Sbjct: 246 TPSVPFTTRTLDKATVL--GEYALPKGTVLMLNTQVLGSSEDNF-EDSSQFRPERWLQEK 302
Query: 246 HA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
P A L F G+R CIG+ A L L VR+ + A E
Sbjct: 303 EKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNE 349
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 84.2 bits (199), Expect = 5e-16
Identities = 54/167 (32%), Positives = 82/167 (49%), Gaps = 1/167 (0%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET A +L++ L + R+ +Q KL E P DL ++ Y +A + E++RL
Sbjct: 329 ETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVP-RAEDLRNMPYLKACLKESMRL 387
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWLAPP 247
P P R DK L G+ +P+GTV ++ V+G + + D++++RPERWL
Sbjct: 388 TPSVPFTTRTLDKATVL--GEYALPKGTVLMLNTQVLGSSEDNF-EDSSQFRPERWLQEK 444
Query: 246 HA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
P A L F G+R CIG+ A L L VR+ + A E
Sbjct: 445 EKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNE 491
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 84.2 bits (199), Expect = 5e-16
Identities = 54/167 (32%), Positives = 82/167 (49%), Gaps = 1/167 (0%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET A +L++ L + R+ +Q KL E P DL ++ Y +A + E++RL
Sbjct: 187 ETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVP-RAEDLRNMPYLKACLKESMRL 245
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWLAPP 247
P P R DK L G+ +P+GTV ++ V+G + + D++++RPERWL
Sbjct: 246 TPSVPFTTRTLDKATVL--GEYALPKGTVLMLNTQVLGSSEDNF-EDSSQFRPERWLQEK 302
Query: 246 HA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
P A L F G+R CIG+ A L L VR+ + A E
Sbjct: 303 EKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNE 349
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 308 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 366
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 367 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 424
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 484
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 485 IKMPQLVLRSKNGFHLHLK 503
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 308 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 366
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 367 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 424
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 484
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 485 IKMPQLVLRSKNGFHLHLK 503
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 308 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 366
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 367 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 424
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 484
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 485 IKMPQLVLRSKNGFHLHLK 503
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 309 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 367
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 368 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 425
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 426 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 485
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 486 IKMPQLVLRSKNGFHLHLK 504
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 294 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 352
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 353 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 410
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 411 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 470
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 471 IKMPQLVLRSKNGFHLHLK 489
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 309 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 367
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 368 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 425
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 426 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 485
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 486 IKMPQLVLRSKNGFHLHLK 504
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 308 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 366
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 367 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 424
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 484
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 485 IKMPQLVLRSKNGFHLHLK 503
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 309 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 367
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 368 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 425
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 426 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 485
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 486 IKMPQLVLRSKNGFHLHLK 504
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 308 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 366
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 367 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 424
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 484
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 485 IKMPQLVLRSKNGFHLHLK 503
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 294 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 352
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 353 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 410
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 411 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 470
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 471 IKMPQLVLRSKNGFHLHLK 489
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 309 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 367
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 368 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 425
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 426 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 485
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 486 IKMPQLVLRSKNGFHLHLK 504
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 308 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 366
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 367 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 424
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 484
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 485 IKMPQLVLRSKNGFHLHLK 503
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 83.4 bits (197), Expect = 9e-16
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + + L + Q + E DL + Y
Sbjct: 294 EVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 352
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 353 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 410
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 411 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 470
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 471 IKMPQLVLRSKNGFHLHLK 489
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/167 (32%), Positives = 83/167 (49%), Gaps = 1/167 (0%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET A +L++ L + R+ +Q KL E RP DL ++ Y +A + E++RL
Sbjct: 328 ETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRP-REEDLRNMPYLKACLKESMRL 386
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWLAPP 247
P P R DK L G+ +P+GTV ++ V+G + + D++++RPERWL
Sbjct: 387 TPGVPFTTRTLDKATVL--GEYALPKGTVLMLNTQVLGSSEDNF-EDSSQFRPERWLQEK 443
Query: 246 HA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE 109
P A L F G+R CIG+ A L L VR+ + A E
Sbjct: 444 EKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNE 490
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 82.2 bits (194), Expect = 2e-15
Identities = 56/199 (28%), Positives = 93/199 (46%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T + + L + Q + E DL + Y
Sbjct: 308 EVDTFMFEGHDTTTGGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTYL 366
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E+ RL+PP P V R K + G+ + P G++ ++ + R +W PD
Sbjct: 367 TMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL-PAGSLISMHIYALHRNSAVW-PDPEV 424
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQ 103
+ R+ ++ P AF+ FS G R CIG+ +AM+ +K V A C+ EF+ + + L
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLP 484
Query: 102 LKL-DVVLRPASGHLLQVK 49
+K+ +VLR +G L +K
Sbjct: 485 IKMPQLVLRSKNGFHLHLK 503
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 60/201 (29%), Positives = 90/201 (44%), Gaps = 4/201 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGAD-LPHLRYC 457
V +L +TV+ TL +AL + R +Q L++E A L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+A V E LRL+P P R+ DKD+ + G ++P+ T+ + R + P+
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQF-PEPNS 427
Query: 276 YRPERWLAP-PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAE--QAEL 106
+RP RWL P P A L F +G+R+C+G+ A L+ LA + E E A +
Sbjct: 428 FRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPV 487
Query: 105 QLKLDVVLRPASGHLLQVKTR 43
+ K VL P LQ R
Sbjct: 488 RPKTRTVLVPERSINLQFLDR 508
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 60/201 (29%), Positives = 90/201 (44%), Gaps = 4/201 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGAD-LPHLRYC 457
V +L +TV+ TL +AL + R +Q L++E A L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+A V E LRL+P P R+ DKD+ + G ++P+ T+ + R + P+
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQF-PEPNS 427
Query: 276 YRPERWLAP-PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAE--QAEL 106
+RP RWL P P A L F +G+R+C+G+ A L+ LA + E E A +
Sbjct: 428 FRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPV 487
Query: 105 QLKLDVVLRPASGHLLQVKTR 43
+ K VL P LQ R
Sbjct: 488 RPKTRTVLVPERSINLQFLDR 508
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 60/201 (29%), Positives = 90/201 (44%), Gaps = 4/201 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGAD-LPHLRYC 457
V +L +TV+ TL +AL + R +Q L++E A L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+A V E LRL+P P R+ DKD+ + G ++P+ T+ + R + P+
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQF-PEPNS 427
Query: 276 YRPERWLAP-PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAE--QAEL 106
+RP RWL P P A L F +G+R+C+G+ A L+ LA + E E A +
Sbjct: 428 FRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPV 487
Query: 105 QLKLDVVLRPASGHLLQVKTR 43
+ K VL P LQ R
Sbjct: 488 RPKTRTVLVPERSINLQFLDR 508
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 60/201 (29%), Positives = 90/201 (44%), Gaps = 4/201 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGAD-LPHLRYC 457
V +L +TV+ TL +AL + R +Q L++E A L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+A V E LRL+P P R+ DKD+ + G ++P+ T+ + R + P+
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQF-PEPNS 427
Query: 276 YRPERWLAP-PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAE--QAEL 106
+RP RWL P P A L F +G+R+C+G+ A L+ LA + E E A +
Sbjct: 428 FRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPV 487
Query: 105 QLKLDVVLRPASGHLLQVKTR 43
+ K VL P LQ R
Sbjct: 488 RPKTRTVLVPERSINLQFLDR 508
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 60/201 (29%), Positives = 90/201 (44%), Gaps = 4/201 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGAD-LPHLRYC 457
V +L +TV+ TL +AL + R +Q L++E A L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+A V E LRL+P P R+ DKD+ + G ++P+ T+ + R + P+
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQF-PEPNS 427
Query: 276 YRPERWLAP-PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAE--QAEL 106
+RP RWL P P A L F +G+R+C+G+ A L+ LA + E E A +
Sbjct: 428 FRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPV 487
Query: 105 QLKLDVVLRPASGHLLQVKTR 43
+ K VL P LQ R
Sbjct: 488 RPKTRTVLVPERSINLQFLDR 508
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 60/201 (29%), Positives = 90/201 (44%), Gaps = 4/201 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGAD-LPHLRYC 457
V +L +TV+ TL +AL + R +Q L++E A L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+A V E LRL+P P R+ DKD+ + G ++P+ T+ + R + P+
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQF-PEPNS 427
Query: 276 YRPERWLAP-PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAE--QAEL 106
+RP RWL P P A L F +G+R+C+G+ A L+ LA + E E A +
Sbjct: 428 FRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPV 487
Query: 105 QLKLDVVLRPASGHLLQVKTR 43
+ K VL P LQ R
Sbjct: 488 RPKTRTVLVPERSINLQFLDR 508
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 60/201 (29%), Positives = 90/201 (44%), Gaps = 4/201 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGAD-LPHLRYC 457
V +L +TV+ TL +AL + R +Q L++E A L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+A V E LRL+P P R+ DKD+ + G ++P+ T+ + R + P+
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQF-PEPNS 427
Query: 276 YRPERWLAP-PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAE--QAEL 106
+RP RWL P P A L F +G+R+C+G+ A L+ LA + E E A +
Sbjct: 428 FRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPV 487
Query: 105 QLKLDVVLRPASGHLLQVKTR 43
+ K VL P LQ R
Sbjct: 488 RPKTRTVLVPERSINLQFLDR 508
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 60/201 (29%), Positives = 90/201 (44%), Gaps = 4/201 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGAD-LPHLRYC 457
V +L +TV+ TL +AL + R +Q L++E A L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+A V E LRL+P P R+ DKD+ + G ++P+ T+ + R + P+
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQF-PEPNS 427
Query: 276 YRPERWLAP-PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAE--QAEL 106
+RP RWL P P A L F +G+R+C+G+ A L+ LA + E E A +
Sbjct: 428 FRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPV 487
Query: 105 QLKLDVVLRPASGHLLQVKTR 43
+ K VL P LQ R
Sbjct: 488 RPKTRTVLVPERSINLQFLDR 508
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 60/201 (29%), Positives = 90/201 (44%), Gaps = 4/201 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGAD-LPHLRYC 457
V +L +TV+ TL +AL + R +Q L++E A L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+A V E LRL+P P R+ DKD+ + G ++P+ T+ + R + P+
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQF-PEPNS 427
Query: 276 YRPERWLAP-PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAE--QAEL 106
+RP RWL P P A L F +G+R+C+G+ A L+ LA + E E A +
Sbjct: 428 FRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPV 487
Query: 105 QLKLDVVLRPASGHLLQVKTR 43
+ K VL P LQ R
Sbjct: 488 RPKTRTVLVPERSINLQFLDR 508
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 77.4 bits (182), Expect = 6e-14
Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 2/198 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + + +
Sbjct: 431 FDPSRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPI 489
Query: 99 KL-DVVLRPASGHLLQVK 49
+ +VL+ +G L+++
Sbjct: 490 PIARLVLKSKNGIHLRLR 507
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 77.4 bits (182), Expect = 6e-14
Identities = 56/198 (28%), Positives = 93/198 (46%), Gaps = 2/198 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRLFPP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLFPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + + +
Sbjct: 431 FDPFRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPI 489
Query: 99 KL-DVVLRPASGHLLQVK 49
+ +VL+ +G L+++
Sbjct: 490 PIARLVLKSKNGIHLRLR 507
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 77.0 bits (181), Expect = 7e-14
Identities = 51/198 (25%), Positives = 94/198 (47%), Gaps = 4/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + L + ++Q KL E P A + + Y + V
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDA-VVQMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R KD++++ +P+G++ + + + W + E+RPER
Sbjct: 362 ETLRLFPVAIRLERTCKKDVEING--VFIPKGSMVVIPTYALHHDPKYW-TEPEEFRPER 418
Query: 261 WLAPPHA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLDV 88
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKLD
Sbjct: 419 FSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDT 478
Query: 87 --VLRPASGHLLQVKTRN 40
+L+P +L+V +R+
Sbjct: 479 QGLLQPEKPIVLKVDSRD 496
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 77.0 bits (181), Expect = 7e-14
Identities = 51/198 (25%), Positives = 94/198 (47%), Gaps = 4/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + L + ++Q KL E P A + + Y + V
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDA-VVQMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R KD++++ +P+G++ + + + W + E+RPER
Sbjct: 362 ETLRLFPVAIRLERTCKKDVEING--VFIPKGSMVVIPTYALHHDPKYW-TEPEEFRPER 418
Query: 261 WLAPPHA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLDV 88
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKLD
Sbjct: 419 FSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDT 478
Query: 87 --VLRPASGHLLQVKTRN 40
+L+P +L+V +R+
Sbjct: 479 QGLLQPEKPIVLKVDSRD 496
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 77.0 bits (181), Expect = 7e-14
Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 2/198 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHGLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + + +
Sbjct: 431 FDPSRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPI 489
Query: 99 KL-DVVLRPASGHLLQVK 49
+ +VL+ +G L+++
Sbjct: 490 PMARLVLKSKNGIHLRLR 507
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 77.0 bits (181), Expect = 7e-14
Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 2/198 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHGLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNLEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + + +
Sbjct: 431 FDPSRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPI 489
Query: 99 KL-DVVLRPASGHLLQVK 49
+ +VL+ +G L+++
Sbjct: 490 PMARLVLKSKNGIHLRLR 507
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 77.0 bits (181), Expect = 7e-14
Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 2/198 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHGLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNLEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + + +
Sbjct: 431 FDPSRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPI 489
Query: 99 KL-DVVLRPASGHLLQVK 49
+ +VL+ +G L+++
Sbjct: 490 PIARLVLKSKNGIHLRLR 507
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 77.0 bits (181), Expect = 7e-14
Identities = 51/198 (25%), Positives = 94/198 (47%), Gaps = 4/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + L + ++Q KL E P A + + Y + V
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDA-VVQMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R KD++++ +P+G++ + + + W + E+RPER
Sbjct: 362 ETLRLFPVAIRLERTCKKDVEING--VFIPKGSMVVIPTYALHHDPKYW-TEPEEFRPER 418
Query: 261 WLAPPHA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLDV 88
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKLD
Sbjct: 419 FSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDT 478
Query: 87 --VLRPASGHLLQVKTRN 40
+L+P +L+V +R+
Sbjct: 479 QGLLQPEKPIVLKVDSRD 496
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 76.2 bits (179), Expect = 1e-13
Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 2/198 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + + +
Sbjct: 431 FDPFRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPI 489
Query: 99 KL-DVVLRPASGHLLQVK 49
+ +VL+ +G L+++
Sbjct: 490 PIARLVLKSKNGIHLRLR 507
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 76.2 bits (179), Expect = 1e-13
Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 2/198 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + + +
Sbjct: 431 FDPFRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPI 489
Query: 99 KL-DVVLRPASGHLLQVK 49
+ +VL+ +G L+++
Sbjct: 490 PIARLVLKSKNGIHLRLR 507
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 76.2 bits (179), Expect = 1e-13
Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 2/198 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + + +
Sbjct: 431 FDPFRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPI 489
Query: 99 KL-DVVLRPASGHLLQVK 49
+ +VL+ +G L+++
Sbjct: 490 PIARLVLKSKNGIHLRLR 507
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 76.2 bits (179), Expect = 1e-13
Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 2/198 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + + +
Sbjct: 431 FDPFRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPI 489
Query: 99 KL-DVVLRPASGHLLQVK 49
+ +VL+ +G L+++
Sbjct: 490 PIARLVLKSKNGIHLRLR 507
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 76.2 bits (179), Expect = 1e-13
Identities = 51/198 (25%), Positives = 94/198 (47%), Gaps = 4/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + L + ++Q KL E P A + + Y + V
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDA-VVQMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R KD++++ +P+G++ + + + W + E+RPER
Sbjct: 362 ETLRLFPVAIRLERTCMKDVEING--VFIPKGSMVVIPTYALHHDPKYW-TEPEEFRPER 418
Query: 261 WLAPPHA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLDV 88
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKLD
Sbjct: 419 FSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDT 478
Query: 87 --VLRPASGHLLQVKTRN 40
+L+P +L+V +R+
Sbjct: 479 QGLLQPEKPIVLKVDSRD 496
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 75.4 bits (177), Expect = 2e-13
Identities = 51/182 (28%), Positives = 83/182 (45%), Gaps = 1/182 (0%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + + +
Sbjct: 431 FDPSRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPI 489
Query: 99 KL 94
+
Sbjct: 490 PI 491
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 74.5 bits (175), Expect = 4e-13
Identities = 55/198 (27%), Positives = 92/198 (46%), Gaps = 2/198 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAELQL 100
+ P R+ AP AQ + AFL FS G R CIGK +AM LK A + E + +
Sbjct: 431 FDPFRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRTPI 489
Query: 99 KL-DVVLRPASGHLLQVK 49
+ +VL+ +G L+++
Sbjct: 490 PMARLVLKSKNGIHLRLR 507
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/200 (25%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 192 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKA-PVTYDALVQMEYLDMVV 250
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 251 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 307
Query: 264 RWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
R+ ++ F G R CIG +A+ +K + ++ F ++ ++ LKL
Sbjct: 308 RFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKL 367
Query: 93 D--VVLRPASGHLLQVKTRN 40
D +L+P +L+V R+
Sbjct: 368 DNLPILQPEKPIVLKVHLRD 387
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/200 (25%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKA-PVTYDALVQMEYLDMVV 360
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 361 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 417
Query: 264 RWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
R+ ++ F G R CIG +A+ +K + ++ F ++ ++ LKL
Sbjct: 418 RFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKL 477
Query: 93 D--VVLRPASGHLLQVKTRN 40
D +L+P +L+V R+
Sbjct: 478 DNLPILQPEKPIVLKVHLRD 497
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/200 (25%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLANKA-PVTYDALVQMEYLDMVV 360
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 361 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 417
Query: 264 RWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
R+ ++ F G R CIG +A+ +K + ++ F ++ ++ LKL
Sbjct: 418 RFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKL 477
Query: 93 D--VVLRPASGHLLQVKTRN 40
D +L+P +L+V R+
Sbjct: 478 DNLPILQPEKPIVLKVHLRD 497
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/200 (25%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKA-PVTYDALVQMEYLDMVV 360
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 361 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 417
Query: 264 RWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
R+ ++ F G R CIG +A+ +K + ++ F ++ ++ LKL
Sbjct: 418 RFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKL 477
Query: 93 D--VVLRPASGHLLQVKTRN 40
D +L+P +L+V R+
Sbjct: 478 DNLPILQPEKPIVLKVHLRD 497
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/200 (25%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKA-PVTYDALVQMEYLDMVV 360
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 361 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 417
Query: 264 RWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
R+ ++ F G R CIG +A+ +K + ++ F ++ ++ LKL
Sbjct: 418 RFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKL 477
Query: 93 D--VVLRPASGHLLQVKTRN 40
D +L+P +L+V R+
Sbjct: 478 DNLPILQPEKPIVLKVHLRD 497
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/200 (25%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKA-PVTYDALVQMEYLDMVV 360
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 361 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 417
Query: 264 RWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
R+ ++ F G R CIG +A+ +K + ++ F ++ ++ LKL
Sbjct: 418 RFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKL 477
Query: 93 D--VVLRPASGHLLQVKTRN 40
D +L+P +L+V R+
Sbjct: 478 DNLPILQPEKPIVLKVHLRD 497
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/200 (25%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKA-PVTYDALVQMEYLDMVV 360
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 361 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 417
Query: 264 RWLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
R+ ++ F G R CIG +A+ +K + ++ F ++ ++ LKL
Sbjct: 418 RFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKL 477
Query: 93 D--VVLRPASGHLLQVKTRN 40
D +L+P +L+V R+
Sbjct: 478 DNLPILQPEKPIVLKVHLRD 497
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 72.5 bits (170), Expect = 2e-12
Identities = 50/201 (24%), Positives = 93/201 (46%), Gaps = 6/201 (2%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKA-PVTYDALVQMEYLDMVV 360
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 361 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 417
Query: 264 RWLAPPHAQPA---AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLK 97
+ + ++ F G R CIG +A+ +K + ++ F ++ ++ LK
Sbjct: 418 SRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLK 477
Query: 96 LD--VVLRPASGHLLQVKTRN 40
LD +L+P +L+V R+
Sbjct: 478 LDNLPILQPEKPIVLKVHLRD 498
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 72.5 bits (170), Expect = 2e-12
Identities = 50/201 (24%), Positives = 93/201 (46%), Gaps = 6/201 (2%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKA-PVTYDALVQMEYLDMVV 360
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 361 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 417
Query: 264 RWLAPPHAQPA---AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLK 97
+ + ++ F G R CIG +A+ +K + ++ F ++ ++ LK
Sbjct: 418 SRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLK 477
Query: 96 LD--VVLRPASGHLLQVKTRN 40
LD +L+P +L+V R+
Sbjct: 478 LDNLPILQPEKPIVLKVHLRD 498
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 153 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 211
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 212 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 268
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 269 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 328
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 329 LGGLLQPEKPVVLKVESRD 347
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 230 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 288
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 289 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 345
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 346 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 405
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 406 LGGLLQPEKPVVLKVESRD 424
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 71.7 bits (168), Expect = 3e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGWVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 71.7 bits (168), Expect = 3e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 302 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 360
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 361 ETLRLFPIAMRLERVCKKDVEING--MFIPKGWVVMIPSYALHRDPKYW-TEPEKFLPER 417
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 418 FSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 477
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 478 LGGLLQPEKPVVLKVESRD 496
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 71.7 bits (168), Expect = 3e-12
Identities = 53/199 (26%), Positives = 84/199 (42%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T L H+T+A ++ + L + + Q++ E +T L + Y
Sbjct: 309 EVSTFLLAGHDTLAASISWILYCLALNPEHQERC-REEVRGILGDGSSITWDQLGEMSYT 367
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ ET RL P P++ R K L G C +P G +S + +W +
Sbjct: 368 TMCIKETCRLIPAVPSISRDLSKPLTFPDG-CTLPAGITVVLSIWGLHHNPAVW-KNPKV 425
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ Q P A+L FS G R CIG+ +AM LK +A + T + L
Sbjct: 426 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPL 485
Query: 105 QLKLDVVLRPASGHLLQVK 49
+L+P +G L +K
Sbjct: 486 TFPNHFILKPKNGMYLHLK 504
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 71.7 bits (168), Expect = 3e-12
Identities = 53/199 (26%), Positives = 84/199 (42%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T L H+T+A ++ + L + + Q++ E +T L + Y
Sbjct: 309 EVSTFLLAGHDTLAASISWILYCLALNPEHQERC-REEVRGILGDGSSITWDQLGEMSYT 367
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ ET RL P P++ R K L G C +P G +S + +W +
Sbjct: 368 TMCIKETCRLIPAVPSISRDLSKPLTFPDG-CTLPAGITVVLSIWGLHHNPAVW-KNPKV 425
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ Q P A+L FS G R CIG+ +AM LK +A + T + L
Sbjct: 426 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPL 485
Query: 105 QLKLDVVLRPASGHLLQVK 49
+L+P +G L +K
Sbjct: 486 TFPNHFILKPKNGMYLHLK 504
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 71.7 bits (168), Expect = 3e-12
Identities = 53/199 (26%), Positives = 84/199 (42%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T L H+T+A ++ + L + + Q++ E +T L + Y
Sbjct: 309 EVSTFLLAGHDTLAASISWILYCLALNPEHQERC-REEVRGILGDGSSITWDQLGEMSYT 367
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ ET RL P P++ R K L G C +P G +S + +W +
Sbjct: 368 TMCIKETCRLIPAVPSISRDLSKPLTFPDG-CTLPAGITVVLSIWGLHHNPAVW-KNPKV 425
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ Q P A+L FS G R CIG+ +AM LK +A + T + L
Sbjct: 426 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPL 485
Query: 105 QLKLDVVLRPASGHLLQVK 49
+L+P +G L +K
Sbjct: 486 TFPNHFILKPKNGMYLHLK 504
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 71.7 bits (168), Expect = 3e-12
Identities = 53/199 (26%), Positives = 84/199 (42%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T L H+T+A ++ + L + + Q++ E +T L + Y
Sbjct: 309 EVSTFLLAGHDTLAASISWILYCLALNPEHQERC-REEVRGILGDGSSITWDQLGEMSYT 367
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ ET RL P P++ R K L G C +P G +S + +W +
Sbjct: 368 TMCIKETCRLIPAVPSISRDLSKPLTFPDG-CTLPAGITVVLSIWGLHHNPAVW-KNPKV 425
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ Q P A+L FS G R CIG+ +AM LK +A + T + L
Sbjct: 426 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPL 485
Query: 105 QLKLDVVLRPASGHLLQVK 49
+L+P +G L +K
Sbjct: 486 TFPNHFILKPKNGMYLHLK 504
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 71.7 bits (168), Expect = 3e-12
Identities = 53/199 (26%), Positives = 84/199 (42%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T L H+T+A ++ + L + + Q++ E +T L + Y
Sbjct: 308 EVSTFLLAGHDTLAASISWILYCLALNPEHQERC-REEVRGILGDGSSITWDQLGEMSYT 366
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ ET RL P P++ R K L G C +P G +S + +W +
Sbjct: 367 TMCIKETCRLIPAVPSISRDLSKPLTFPDG-CTLPAGITVVLSIWGLHHNPAVW-KNPKV 424
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ Q P A+L FS G R CIG+ +AM LK +A + T + L
Sbjct: 425 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPL 484
Query: 105 QLKLDVVLRPASGHLLQVK 49
+L+P +G L +K
Sbjct: 485 TFPNHFILKPKNGMYLHLK 503
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 71.7 bits (168), Expect = 3e-12
Identities = 49/171 (28%), Positives = 78/171 (45%), Gaps = 3/171 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V +L +T + TL + + ++ R +Q +Y E P T AD+P +
Sbjct: 174 VTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVP-TAADVPKVPLVR 232
Query: 453 ATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEY 274
A + ETLRLFP P R+ +DL + G ++P+GT A+ + P A E+
Sbjct: 233 ALLKETLRLFPVLPGNGRVTQEDLVI--GGYLIPKGTQLALCHYATSYQDENF-PRAKEF 289
Query: 273 RPERWLAP---PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELE 130
RPERWL + F +G R+CIG+ A + V+ ++ E
Sbjct: 290 RPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFE 340
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 71.7 bits (168), Expect = 3e-12
Identities = 53/199 (26%), Positives = 84/199 (42%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T L H+T+A ++ + L + + Q++ E +T L + Y
Sbjct: 309 EVSTFLLAGHDTLAASISWILYCLALNPEHQERC-REEVRGILGDGSSITWDQLGEMSYT 367
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ ET RL P P++ R K L G C +P G +S + +W +
Sbjct: 368 TMCIKETCRLIPAVPSISRDLSKPLTFPDG-CTLPAGITVVLSIWGLHHNPAVW-KNPKV 425
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ Q P A+L FS G R CIG+ +AM LK +A + T + L
Sbjct: 426 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPL 485
Query: 105 QLKLDVVLRPASGHLLQVK 49
+L+P +G L +K
Sbjct: 486 TFPNHFILKPKNGMYLHLK 504
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 71.7 bits (168), Expect = 3e-12
Identities = 53/199 (26%), Positives = 84/199 (42%), Gaps = 3/199 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T L H+T+A ++ + L + + Q++ E +T L + Y
Sbjct: 244 EVSTFLLAGHDTLAASISWILYCLALNPEHQERC-REEVRGILGDGSSITWDQLGEMSYT 302
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ ET RL P P++ R K L G C +P G +S + +W +
Sbjct: 303 TMCIKETCRLIPAVPSISRDLSKPLTFPDG-CTLPAGITVVLSIWGLHHNPAVW-KNPKV 360
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ Q P A+L FS G R CIG+ +AM LK +A + T + L
Sbjct: 361 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPL 420
Query: 105 QLKLDVVLRPASGHLLQVK 49
+L+P +G L +K
Sbjct: 421 TFPNHFILKPKNGMYLHLK 439
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGWVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 304 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 362
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 363 ETLRLFPIAMRLERVCKKDVEING--MFIPKGWVVMIPSYALHRDPKYW-TEPEKFLPER 419
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 420 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 479
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 480 LGGLLQPEKPVVLKVESRD 498
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/159 (30%), Positives = 76/159 (47%), Gaps = 1/159 (0%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 315 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 373
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ + P+G + +S + ++W P+
Sbjct: 374 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKVW-PNPEV 431
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILK 163
+ P R+ AP AQ + AFL FS G R CIGK +AM LK
Sbjct: 432 FDPFRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNELK 469
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/199 (24%), Positives = 95/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 304 IFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 362
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 363 ETLRLFPIAMRLERVCKKDVEING--MFIPKGWVVMIPSYALHRDPKYW-TEPEKFLPER 419
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 420 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 479
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 480 LGGLLQPEKPVVLKVESRD 498
>BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family
27, subfamily C, polypeptide 1 protein.
Length = 372
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/171 (28%), Positives = 78/171 (45%), Gaps = 3/171 (1%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V +L +T + TL + + ++ R +Q +Y E P T AD+P +
Sbjct: 174 VTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERHVP-TAADVPKVPLVR 232
Query: 453 ATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEY 274
A + ETLRLFP P R+ +DL + G ++P+GT A+ + P A E+
Sbjct: 233 ALLKETLRLFPVLPGNGRVTQEDLVI--GGYLIPKGTQLALCHYATSYQDENF-PRAKEF 289
Query: 273 RPERWLAP---PHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELE 130
RPERWL + F +G R+CIG+ A + V+ ++ E
Sbjct: 290 RPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFE 340
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 70.9 bits (166), Expect = 5e-12
Identities = 51/191 (26%), Positives = 89/191 (46%), Gaps = 8/191 (4%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+L +T + TL +AL + +D +Q+ L+ E P D H+ +A +
Sbjct: 331 LLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVP-QHKDFAHMPLLKAVL 389
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRL+P P R+ +K++++ + P+ T V+ R + + ++P
Sbjct: 390 KETLRLYPVVPTNSRIIEKEIEVDG--FLFPKNTQFVFCHYVVSRDPTAFS-EPESFQPH 446
Query: 264 RWL-----APPHAQ-PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELE--FTAEQAE 109
RWL A P Q P + F YG RAC+G+ A ++ +LA +++ + E E
Sbjct: 447 RWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGE 506
Query: 108 LQLKLDVVLRP 76
L+ +VL P
Sbjct: 507 LKSVARIVLVP 517
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 70.9 bits (166), Expect = 5e-12
Identities = 51/191 (26%), Positives = 89/191 (46%), Gaps = 8/191 (4%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+L +T + TL +AL + +D +Q+ L+ E P D H+ +A +
Sbjct: 332 LLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVP-QHKDFAHMPLLKAVL 390
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRL+P P R+ +K++++ + P+ T V+ R + + ++P
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDG--FLFPKNTQFVFCHYVVSRDPTAFS-EPESFQPH 447
Query: 264 RWL-----APPHAQ-PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELE--FTAEQAE 109
RWL A P Q P + F YG RAC+G+ A ++ +LA +++ + E E
Sbjct: 448 RWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGE 507
Query: 108 LQLKLDVVLRP 76
L+ +VL P
Sbjct: 508 LKSVARIVLVP 518
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 70.9 bits (166), Expect = 5e-12
Identities = 50/198 (25%), Positives = 87/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 339 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 398
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 399 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 455
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + + +K L + + F A Q LQL+
Sbjct: 456 FTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 515
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 516 SKSALGPKNGVYIKIVSR 533
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 70.9 bits (166), Expect = 5e-12
Identities = 51/191 (26%), Positives = 89/191 (46%), Gaps = 8/191 (4%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+L +T + TL +AL + +D +Q+ L+ E P D H+ +A +
Sbjct: 332 LLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVP-QHKDFAHMPLLKAVL 390
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRL+P P R+ +K++++ + P+ T V+ R + + ++P
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDG--FLFPKNTQFVFCHYVVSRDPTAFS-EPESFQPH 447
Query: 264 RWL-----APPHAQ-PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELE--FTAEQAE 109
RWL A P Q P + F YG RAC+G+ A ++ +LA +++ + E E
Sbjct: 448 RWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGE 507
Query: 108 LQLKLDVVLRP 76
L+ +VL P
Sbjct: 508 LKSVARIVLVP 518
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 70.9 bits (166), Expect = 5e-12
Identities = 51/191 (26%), Positives = 89/191 (46%), Gaps = 8/191 (4%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+L +T + TL +AL + +D +Q+ L+ E P D H+ +A +
Sbjct: 332 LLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVP-QHKDFAHMPLLKAVL 390
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRL+P P R+ +K++++ + P+ T V+ R + + ++P
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDG--FLFPKNTQFVFCHYVVSRDPTAFS-EPESFQPH 447
Query: 264 RWL-----APPHAQ-PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELE--FTAEQAE 109
RWL A P Q P + F YG RAC+G+ A ++ +LA +++ + E E
Sbjct: 448 RWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGE 507
Query: 108 LQLKLDVVLRP 76
L+ +VL P
Sbjct: 508 LKSVARIVLVP 518
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.9 bits (166), Expect = 5e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPENFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 272 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 331
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 332 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 388
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 389 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 448
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 449 SKSALGPKNGVYIKIVSR 466
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHA--QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A QP +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPKTFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAEDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.5 bits (165), Expect = 6e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 70.1 bits (164), Expect = 9e-12
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 5/198 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
L +E + TL +A ++ + + Q+KL E P + L Y + +
Sbjct: 340 LIAGYEIITNTLSFATYVLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLR++PP R A +D ++ + +P G V ++ + W P + PER
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHW-PSPETFNPER 456
Query: 261 WLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA---EQAELQLK 97
+ A Q P +L F G R+C+G + +K L + + F A Q LQL+
Sbjct: 457 FTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLE 516
Query: 96 LDVVLRPASGHLLQVKTR 43
L P +G +++ +R
Sbjct: 517 SKSALGPKNGVYIKIVSR 534
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 70.1 bits (164), Expect = 9e-12
Identities = 49/199 (24%), Positives = 94/199 (47%), Gaps = 5/199 (2%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F ET ++ L + + + ++Q KL E P L + Y + V
Sbjct: 303 IFAGCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL-QMEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + + R + W + ++ PER
Sbjct: 362 ETLRLFPIAMRLERVCKKDVEING--MFIPKGVVVMIPSYALHRDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLD 91
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLS 478
Query: 90 V--VLRPASGHLLQVKTRN 40
+ +L+P +L+V++R+
Sbjct: 479 LGGLLQPEKPVVLKVESRD 497
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 69.7 bits (163), Expect = 1e-11
Identities = 52/197 (26%), Positives = 87/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 627 TVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEAT 448
T HET A L + ++ + R + +L E + DL L+Y
Sbjct: 298 TFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRY-LDFEDLGRLQYLSQV 356
Query: 447 VLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRP 268
+ E+LRL+PP R+ +++ + + VP T S VMGR + D + P
Sbjct: 357 LKESLRLYPPAWGTFRLLEEETLIDGVR--VPGNTPLLFSTYVMGRMDTYF-EDPLTFNP 413
Query: 267 ERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-LQLKL 94
+R+ P +P + FS G R+CIG+ +A +K V+A ++ LEF + L+
Sbjct: 414 DRF-GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQE 472
Query: 93 DVVLRPASGHLLQVKTR 43
L+P L ++ R
Sbjct: 473 QATLKPLDPVLCTLRPR 489
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 69.7 bits (163), Expect = 1e-11
Identities = 52/197 (26%), Positives = 87/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 627 TVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEAT 448
T HET A L + ++ + R + +L E + DL L+Y
Sbjct: 298 TFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRY-LDFEDLGRLQYLSQV 356
Query: 447 VLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRP 268
+ E+LRL+PP R+ +++ + + VP T S VMGR + D + P
Sbjct: 357 LKESLRLYPPAWGTFRLLEEETLIDGVR--VPGNTPLLFSTYVMGRMDTYF-EDPLTFNP 413
Query: 267 ERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-LQLKL 94
+R+ P +P + FS G R+CIG+ +A +K V+A ++ LEF + L+
Sbjct: 414 DRF-GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQE 472
Query: 93 DVVLRPASGHLLQVKTR 43
L+P L ++ R
Sbjct: 473 QATLKPLDPVLCTLRPR 489
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 67.3 bits (157), Expect = 6e-11
Identities = 44/179 (24%), Positives = 82/179 (45%), Gaps = 3/179 (1%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q K+ E P L L Y + V
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL-QLEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + V+ + W + ++ PER
Sbjct: 362 ETLRLFPVAMRLERVCKKDVEING--MFIPKGVVVMIPSYVLHHDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKL 477
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 67.3 bits (157), Expect = 6e-11
Identities = 44/179 (24%), Positives = 82/179 (45%), Gaps = 3/179 (1%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q K+ E P L L Y + V
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL-QLEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + V+ + W + ++ PER
Sbjct: 362 ETLRLFPVAMRLERVCKKDVEING--MFIPKGVVVMIPSYVLHHDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKL 477
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 67.3 bits (157), Expect = 6e-11
Identities = 50/191 (26%), Positives = 87/191 (45%), Gaps = 8/191 (4%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+L +T + TL +AL + +D +Q L+ E P D H+ +A +
Sbjct: 332 LLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQVP-QHKDFAHMPLLKAVL 390
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRL+P P R+ +K++++ + P+ T + R + + ++P
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDG--FLFPKNTQFVFCHYEVSRDPTAFS-EPESFQPH 447
Query: 264 RWL-----APPHAQ-PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELE--FTAEQAE 109
RWL A P Q P + F YG RAC+G+ A ++ +LA +++ + E E
Sbjct: 448 RWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGE 507
Query: 108 LQLKLDVVLRP 76
L+ +VL P
Sbjct: 508 LKSVARIVLVP 518
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 67.3 bits (157), Expect = 6e-11
Identities = 44/179 (24%), Positives = 82/179 (45%), Gaps = 3/179 (1%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q K+ E P L L Y + V
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL-QLEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + V+ + W + ++ PER
Sbjct: 362 ETLRLFPVAMRLERVCKKDVEING--MFIPKGVVVMIPSYVLHHDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKL 477
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 67.3 bits (157), Expect = 6e-11
Identities = 44/179 (24%), Positives = 82/179 (45%), Gaps = 3/179 (1%)
Frame = -3
Query: 621 LFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVL 442
+F +ET ++ L + + + ++Q K+ E P L L Y + V
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL-QLEYLDMVVN 361
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRLFP + R+ KD++++ +P+G V + + V+ + W + ++ PER
Sbjct: 362 ETLRLFPVAMRLERVCKKDVEING--MFIPKGVVVMIPSYVLHHDPKYW-TEPEKFLPER 418
Query: 261 WLA--PPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKL 94
+ + P + F G R CIG +A+ +K L ++ F ++ ++ LKL
Sbjct: 419 FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKL 477
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 65.3 bits (152), Expect = 2e-10
Identities = 56/196 (28%), Positives = 89/196 (45%), Gaps = 4/196 (2%)
Frame = -3
Query: 615 GXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGA--DLPHLRYCEATVL 442
G +T L+ L + R+ N+Q L E A +LP LR A +
Sbjct: 314 GSMDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLR---AALK 370
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRL+P + R+A DL L + +P GT+ V +GR L+ P Y P+R
Sbjct: 371 ETLRLYPVGLFLERVASSDLVLQNYH--IPAGTLVRVFLYSLGRNPALF-PRPERYNPQR 427
Query: 261 WL-APPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLDV 88
WL + + F +G R C+G+ A A + +L ++ L+ T Q ++++
Sbjct: 428 WLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSF 487
Query: 87 VLRPASGHLLQVKTRN 40
+LRP+ LL + N
Sbjct: 488 ILRPSMFPLLTFRAIN 503
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 64.9 bits (151), Expect = 3e-10
Identities = 56/196 (28%), Positives = 89/196 (45%), Gaps = 4/196 (2%)
Frame = -3
Query: 615 GXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGA--DLPHLRYCEATVL 442
G +T L+ L + R+ N+Q L E A +LP LR A +
Sbjct: 314 GSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLR---AALK 370
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRL+P + R+A DL L + +P GT+ V +GR L+ P Y P+R
Sbjct: 371 ETLRLYPVGLFLERVASSDLVLQNYH--IPAGTLVRVFLYSLGRNPALF-PRPERYNPQR 427
Query: 261 WL-APPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLDV 88
WL + + F +G R C+G+ A A + +L ++ L+ T Q ++++
Sbjct: 428 WLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSF 487
Query: 87 VLRPASGHLLQVKTRN 40
+LRP+ LL + N
Sbjct: 488 ILRPSMCPLLTFRAIN 503
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 64.9 bits (151), Expect = 3e-10
Identities = 56/196 (28%), Positives = 89/196 (45%), Gaps = 4/196 (2%)
Frame = -3
Query: 615 GXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGA--DLPHLRYCEATVL 442
G +T L+ L + R+ N+Q L E A +LP LR A +
Sbjct: 314 GSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLR---AALK 370
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRL+P + R+A DL L + +P GT+ V +GR L+ P Y P+R
Sbjct: 371 ETLRLYPVGLFLERVASSDLVLQNYH--IPAGTLVRVFLYSLGRNPALF-PRPERYNPQR 427
Query: 261 WL-APPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLDV 88
WL + + F +G R C+G+ A A + +L ++ L+ T Q ++++
Sbjct: 428 WLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSF 487
Query: 87 VLRPASGHLLQVKTRN 40
+LRP+ LL + N
Sbjct: 488 ILRPSMFPLLTFRAIN 503
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 64.9 bits (151), Expect = 3e-10
Identities = 56/196 (28%), Positives = 89/196 (45%), Gaps = 4/196 (2%)
Frame = -3
Query: 615 GXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGA--DLPHLRYCEATVL 442
G +T L+ L + R+ N+Q L E A +LP LR A +
Sbjct: 385 GSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLR---AALK 441
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRL+P + R+A DL L + +P GT+ V +GR L+ P Y P+R
Sbjct: 442 ETLRLYPVGLFLERVASSDLVLQNYH--IPAGTLVRVFLYSLGRNPALF-PRPERYNPQR 498
Query: 261 WL-APPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLDV 88
WL + + F +G R C+G+ A A + +L ++ L+ T Q ++++
Sbjct: 499 WLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSF 558
Query: 87 VLRPASGHLLQVKTRN 40
+LRP+ LL + N
Sbjct: 559 ILRPSMFPLLTFRAIN 574
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/156 (26%), Positives = 77/156 (49%), Gaps = 4/156 (2%)
Frame = -3
Query: 495 PVTGADLPHLRYCEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVM 316
P T + + Y + V ETLRLFP + R KD++++ +P+G++ + +
Sbjct: 15 PPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEING--VFIPKGSMVVIPTYAL 72
Query: 315 GRARRLWGPDAAEYRPERWLAPPHA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVR 139
+ W + E+RPER+ + P + F G R CIG +A+ +K L ++
Sbjct: 73 HHDPKYW-TEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQ 131
Query: 138 ELEF-TAEQAELQLKLDV--VLRPASGHLLQVKTRN 40
F ++ ++ LKLD +L+P +L+V +R+
Sbjct: 132 NFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSRD 167
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/156 (26%), Positives = 77/156 (49%), Gaps = 4/156 (2%)
Frame = -3
Query: 495 PVTGADLPHLRYCEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVM 316
P T + + Y + V ETLRLFP + R KD++++ +P+G++ + +
Sbjct: 2 PPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEING--VFIPKGSMVVIPTYAL 59
Query: 315 GRARRLWGPDAAEYRPERWLAPPHA-QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVR 139
+ W + E+RPER+ + P + F G R CIG +A+ +K L ++
Sbjct: 60 HHDPKYW-TEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQ 118
Query: 138 ELEF-TAEQAELQLKLDV--VLRPASGHLLQVKTRN 40
F ++ ++ LKLD +L+P +L+V +R+
Sbjct: 119 NFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSRD 154
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 63.3 bits (147), Expect = 1e-09
Identities = 55/196 (28%), Positives = 88/196 (44%), Gaps = 4/196 (2%)
Frame = -3
Query: 615 GXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGA--DLPHLRYCEATVL 442
G +T L+ L + R+ N+Q L E A +LP LR A +
Sbjct: 314 GSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLR---AALK 370
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRL+P + R+ DL L + +P GT+ V +GR L+ P Y P+R
Sbjct: 371 ETLRLYPVGLFLERVVSSDLVLQNYH--IPAGTLVRVFLYSLGRNPALF-PRPERYNPQR 427
Query: 261 WL-APPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF-TAEQAELQLKLDV 88
WL + + F +G R C+G+ A A + +L ++ L+ T Q ++++
Sbjct: 428 WLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSF 487
Query: 87 VLRPASGHLLQVKTRN 40
+LRP+ LL + N
Sbjct: 488 ILRPSMFPLLTFRAIN 503
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 62.9 bits (146), Expect = 1e-09
Identities = 43/145 (29%), Positives = 72/145 (49%), Gaps = 2/145 (1%)
Frame = -3
Query: 477 LPHLRYCEATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRL 298
L + Y + E LRL+PP P + R + G+ + P+G + +S + ++
Sbjct: 268 LDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSL-PKGIMVLLSIYGLHHNPKV 326
Query: 297 WGPDAAEYRPERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTA 121
W P+ + P R+ AP AQ + AFL FS G R CIGK +AM LK A + E
Sbjct: 327 W-PNLEVFDPSRF-APGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLP 384
Query: 120 EQAELQLKL-DVVLRPASGHLLQVK 49
+ + + + +VL+ +G L+++
Sbjct: 385 DPTRIPIPMARLVLKSKNGIHLRLR 409
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 4/196 (2%)
Frame = -3
Query: 615 GXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGA--DLPHLRYCEATVL 442
G +T A L+ L + R+ ++Q L E A +LP LR A +
Sbjct: 314 GSVDTTAFPLLMTLFELARNPDVQQILRKESLAAAASISEHPQKATTELPLLR---AALK 370
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRL+P + R+ DL L + +P GT+ V +GR L+ P Y P+R
Sbjct: 371 ETLRLYPVGLFLERVVSSDLVLQNYH--IPAGTLVQVFLYSLGRNAALF-PRPERYNPQR 427
Query: 261 WL-APPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCV-RELEFTAEQAELQLKLDV 88
WL + + F +G R C+G+ A A + +L + R L T Q ++++
Sbjct: 428 WLDIRGSGRNLHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKRFLVETLTQEDIKMVYSF 487
Query: 87 VLRPASGHLLQVKTRN 40
+LRP + LL + N
Sbjct: 488 ILRPGTSPLLTFRAIN 503
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 61.7 bits (143), Expect = 3e-09
Identities = 55/196 (28%), Positives = 88/196 (44%), Gaps = 4/196 (2%)
Frame = -3
Query: 615 GXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGA--DLPHLRYCEATVL 442
G +T A L+ L + R+ ++Q L E A +LP LR A +
Sbjct: 314 GSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLR---AALK 370
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRL+P + R+ DL L + +P GT+ V +GR L+ P Y P+R
Sbjct: 371 ETLRLYPVGLFLERVVSSDLVLQNYH--IPAGTLVQVFLYSLGRNAALF-PRPERYNPQR 427
Query: 261 WL-APPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRE-LEFTAEQAELQLKLDV 88
WL + + F +G R C+G+ A A + +L ++ L T Q ++++
Sbjct: 428 WLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSF 487
Query: 87 VLRPASGHLLQVKTRN 40
+LRP + LL + N
Sbjct: 488 ILRPGTSPLLTFRAIN 503
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 61.7 bits (143), Expect = 3e-09
Identities = 55/196 (28%), Positives = 88/196 (44%), Gaps = 4/196 (2%)
Frame = -3
Query: 615 GXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGA--DLPHLRYCEATVL 442
G +T A L+ L + R+ ++Q L E A +LP LR A +
Sbjct: 314 GSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLR---AALK 370
Query: 441 ETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPER 262
ETLRL+P + R+ DL L + +P GT+ V +GR L+ P Y P+R
Sbjct: 371 ETLRLYPVGLFLERVVSSDLVLQNYH--IPAGTLVQVFLYSLGRNAALF-PRPERYNPQR 427
Query: 261 WL-APPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRE-LEFTAEQAELQLKLDV 88
WL + + F +G R C+G+ A A + +L ++ L T Q ++++
Sbjct: 428 WLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSF 487
Query: 87 VLRPASGHLLQVKTRN 40
+LRP + LL + N
Sbjct: 488 ILRPGTSPLLTFRAIN 503
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 312 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 370
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 371 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 427
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 428 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 470
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 185 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 243
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 244 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 300
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 301 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 343
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 312 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 370
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 371 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 427
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 428 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 470
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDMIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 308 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 366
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 367 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 423
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 424 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 466
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 258 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 316
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 317 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 373
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 374 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 416
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDEVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 258 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 316
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 317 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 373
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 374 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 416
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 258 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 316
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 317 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 373
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 374 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 416
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/173 (25%), Positives = 80/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRD----KNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
+LFG HET A+ + +G + ++++L ++ + L L+Y
Sbjct: 228 LLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYI 287
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ ETLRL PP P R+A K +L+ + +P+G S ++ + E
Sbjct: 288 GCVIKETLRLNPPVPGGFRVALKTFELNGYQ--IPKGWNVIYSICDTHDVAEIF-TNKEE 344
Query: 276 YRPERWLAPPHAQPA---AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF 127
+ P+R++ PH + A +F+ F G R+C+GK +A +LK R ++
Sbjct: 345 FNPDRFML-PHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDW 396
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/173 (25%), Positives = 80/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRD----KNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
+LFG HET A+ + +G + ++++L ++ + L L+Y
Sbjct: 297 LLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYI 356
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ ETLRL PP P R+A K +L+ + +P+G S ++ + E
Sbjct: 357 GCVIKETLRLNPPVPGGFRVALKTFELNGYQ--IPKGWNVIYSICDTHDVAEIF-TNKEE 413
Query: 276 YRPERWLAPPHAQPA---AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF 127
+ P+R++ PH + A +F+ F G R+C+GK +A +LK R ++
Sbjct: 414 FNPDRFML-PHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDW 465
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/173 (25%), Positives = 80/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRD----KNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
+LFG HET A+ + +G + ++++L ++ + L L+Y
Sbjct: 297 LLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYI 356
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ ETLRL PP P R+A K +L+ + +P+G S ++ + E
Sbjct: 357 GCVIKETLRLNPPVPGGFRVALKTFELNGYQ--IPKGWNVIYSICDTHDVAEIF-TNKEE 413
Query: 276 YRPERWLAPPHAQPA---AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF 127
+ P+R++ PH + A +F+ F G R+C+GK +A +LK R ++
Sbjct: 414 FNPDRFML-PHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDW 465
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 378 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 436
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P V M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 437 DIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 493
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 494 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 536
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T + ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 314 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 372
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L +P+G V+ + ++LW + +E+
Sbjct: 373 LETFRHSSFVPF-TIPHSTTRDTSLKG--FYIPKGRCVFVNQWQINHDQKLW-VNPSEFL 428
Query: 270 PERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 429 PERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFS 481
>M12079-1|AAA52152.1| 191|Homo sapiens POR protein.
Length = 191
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T + ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 20 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 78
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L +P+G V+ + ++LW + +E+
Sbjct: 79 LETFRHSSFVPF-TIPHSTTRDTSLKG--FYIPKGRCVFVNQWQINHDQKLW-VNPSEFL 134
Query: 270 PERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 135 PERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETVARWEVFLFLAILLQRVEFS 187
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T + ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 314 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 372
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L +P+G V+ + ++LW + +E+
Sbjct: 373 LETFRHSSFVPF-TIPHSTTRDTSLKG--FYIPKGRCVFVNQWQINHDQKLW-VNPSEFL 428
Query: 270 PERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 429 PERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETVARWEVFLFLAILLQRVEFS 481
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T + ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 314 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 372
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L +P+G V+ + ++LW + +E+
Sbjct: 373 LETFRHSSFVPF-TIPHSTTRDTSLKG--FYIPKGRCVFVNQWQINHDQKLW-VNPSEFL 428
Query: 270 PERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 429 PERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFS 481
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T + ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 314 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 372
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L +P+G V+ + ++LW + +E+
Sbjct: 373 LETFRHSSFVPF-TIPHSTTRDTSLKG--FYIPKGRCVFVNQWQINHDQKLW-VNPSEFL 428
Query: 270 PERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 429 PERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFS 481
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T + ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 286 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 344
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L +P+G V+ + ++LW + +E+
Sbjct: 345 LETFRHSSFVPF-TIPHSTTRDTSLKG--FYIPKGRCVFVNQWQINHDQKLW-VNPSEFL 400
Query: 270 PERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 401 PERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFS 453
>AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1
protein.
Length = 251
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T + ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 53 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 111
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L +P+G V+ + ++LW + +E+
Sbjct: 112 LETFRHSSFVPF-TIPHSTTRDTSLKG--FYIPKGRCVFVNQWQINHDQKLW-VNPSEFL 167
Query: 270 PERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 168 PERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFS 220
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T + ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 314 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 372
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L +P+G V+ + ++LW + +E+
Sbjct: 373 LETFRHSSFVPF-TIPHSTTRDTSLKG--FYIPKGRCVFVNQWQINHDQKLW-VNPSEFL 428
Query: 270 PERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 429 PERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFS 481
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T + ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 314 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 372
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L +P+G V+ + ++LW + +E+
Sbjct: 373 LETFRHSSFVPF-TIPHSTTRDTSLKG--FYIPKGRCVFVNQWQINHDQKLW-VNPSEFL 428
Query: 270 PERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 429 PERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFS 481
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/163 (27%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P + M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGMTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/163 (27%), Positives = 75/163 (46%), Gaps = 3/163 (1%)
Frame = -3
Query: 603 TVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRLF 424
T +TTL + LL++ ++Q ++ E RP G D H+ Y A + E R
Sbjct: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG-DQAHMPYTTAVIHEVQRFG 367
Query: 423 PPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-AP 250
P + M +D+++ + +P+GT + + + +W + PE +L A
Sbjct: 368 DIVPLGMTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQ 424
Query: 249 PH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
H +P AFL FS GRRAC+G+ A L S ++ F+
Sbjct: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/193 (23%), Positives = 82/193 (42%), Gaps = 3/193 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T +F H+T ++ + + L + + Q + +E +T L + Y
Sbjct: 307 EVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYT 365
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+ P + R+ DK + G+ + P G ++ + W D
Sbjct: 366 TMCIKECLRLYAPVVNISRLLDKPITFPDGRSL-PAGITVFINIWALHHNPYFW-EDPQV 423
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ + P AF+ FS G R CIG+++A+ K +A + + + +
Sbjct: 424 FNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPP 483
Query: 105 QLKLDVVLRPASG 67
Q VVL+ +G
Sbjct: 484 QPVRQVVLKSKNG 496
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/193 (23%), Positives = 82/193 (42%), Gaps = 3/193 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T +F H+T ++ + + L + + Q + +E +T L + Y
Sbjct: 307 EVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYT 365
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+ P + R+ DK + G+ + P G ++ + W D
Sbjct: 366 TMCIKECLRLYAPVVNISRLLDKPITFPDGRSL-PAGITVFINIWALHHNPYFW-EDPQV 423
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ + P AF+ FS G R CIG+++A+ K +A + + + +
Sbjct: 424 FNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPP 483
Query: 105 QLKLDVVLRPASG 67
Q VVL+ +G
Sbjct: 484 QPVRQVVLKSKNG 496
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/193 (23%), Positives = 82/193 (42%), Gaps = 3/193 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T +F H+T ++ + + L + + Q + +E +T L + Y
Sbjct: 307 EVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYT 365
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+ P + R+ DK + G+ + P G ++ + W D
Sbjct: 366 TMCIKECLRLYAPVVNISRLLDKPITFPDGRSL-PAGITVFINIWALHHNPYFW-EDPQV 423
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ + P AF+ FS G R CIG+++A+ K +A + + + +
Sbjct: 424 FNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPP 483
Query: 105 QLKLDVVLRPASG 67
Q VVL+ +G
Sbjct: 484 QPVRQVVLKSKNG 496
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/193 (23%), Positives = 82/193 (42%), Gaps = 3/193 (1%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EV T +F H+T ++ + + L + + Q + +E +T L + Y
Sbjct: 307 EVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYT 365
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+ P + R+ DK + G+ + P G ++ + W D
Sbjct: 366 TMCIKECLRLYAPVVNISRLLDKPITFPDGRSL-PAGITVFINIWALHHNPYFW-EDPQV 423
Query: 276 YRPERWLAPPHAQ--PAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-L 106
+ P R+ + P AF+ FS G R CIG+++A+ K +A + + + +
Sbjct: 424 FNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPP 483
Query: 105 QLKLDVVLRPASG 67
Q VVL+ +G
Sbjct: 484 QPVRQVVLKSKNG 496
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 58.0 bits (134), Expect = 4e-08
Identities = 50/173 (28%), Positives = 80/173 (46%), Gaps = 7/173 (4%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 314 LFGAGFDTVTTATSWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 372
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L +P+G V+ + ++LW + +E+
Sbjct: 373 LETFRHSSFVPF-TIPHSTTRDTSLKG--FYIPKGRCVFVNQWQIDHDQKLW-VNPSEFL 428
Query: 270 PERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 429 PERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFS 481
>AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
Homo sapiens cholesterol 24-hydroxylase mRNA. ).
Length = 337
Score = 58.0 bits (134), Expect = 4e-08
Identities = 49/197 (24%), Positives = 83/197 (42%), Gaps = 2/197 (1%)
Frame = -3
Query: 627 TVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEAT 448
T HET A L + ++ + R + +L E + DL L+Y
Sbjct: 145 TFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRY-LDFEDLGRLQYLSQV 203
Query: 447 VLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRP 268
+ E+LRL+PP R+ +++ + S VMGR + D + P
Sbjct: 204 LKESLRLYPPAWGTFRLLEEETLIDG------------FSTYVMGRMDTYF-EDPLTFNP 250
Query: 267 ERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-LQLKL 94
+R+ P +P + FS G R+CIG+ +A +K V+A ++ LEF + L+
Sbjct: 251 DRF-GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQE 309
Query: 93 DVVLRPASGHLLQVKTR 43
L+P L ++ R
Sbjct: 310 QATLKPLDPVLCTLRPR 326
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 57.6 bits (133), Expect = 5e-08
Identities = 48/172 (27%), Positives = 79/172 (45%), Gaps = 6/172 (3%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
LFG +TV T + ++L+ + + +Q K+ E RP +D HL Y EA +
Sbjct: 314 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL-SDRSHLPYMEAFI 372
Query: 444 LETLRLFPPFPAVL-RMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRP 268
LET R P + +D L +P+G V+ + ++LW + +E+ P
Sbjct: 373 LETFRHSSLVPFTIPHSTTRDTSLKG--FYIPKGRCVFVNQWQINHDQKLW-VNPSEFLP 429
Query: 267 ERWLAPPHAQPAAF----LAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
ER+L P A + F G+R CIG+ A + LA ++ +EF+
Sbjct: 430 ERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETVARWEVFLFLAILLQRVEFS 481
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 6/197 (3%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+ F ET +TTL +ALL + +Q+K+ E +P T A + Y A +
Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR-ESMPYTNAVI 366
Query: 444 LETLRLFPPFPA-VLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWG-PDAAEYR 271
E R+ P V R D L+ +P+GT+ + + R W PD +
Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLAGYH--LPKGTMILTNLTALHRDPTEWATPDT--FN 422
Query: 270 PERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF---TAEQAELQ 103
P+ +L + AF+ FS G+RAC+G+ A L S +++ F E+ L+
Sbjct: 423 PDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLK 482
Query: 102 LKLDVVLRPASGHLLQV 52
++ + + P S L V
Sbjct: 483 FRMGITISPVSHRLCAV 499
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 6/197 (3%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+ F ET +TTL +ALL + +Q+K+ E +P T A + Y A +
Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR-ESMPYTNAVI 366
Query: 444 LETLRLFPPFPA-VLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWG-PDAAEYR 271
E R+ P V R D L+ +P+GT+ + + R W PD +
Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLAGYH--LPKGTMILTNLTALHRDPTEWATPDT--FN 422
Query: 270 PERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF---TAEQAELQ 103
P+ +L + AF+ FS G+RAC+G+ A L S +++ F E+ L+
Sbjct: 423 PDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLK 482
Query: 102 LKLDVVLRPASGHLLQV 52
++ + + P S L V
Sbjct: 483 FRMGITISPVSHRLCAV 499
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 6/197 (3%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+ F ET +TTL +ALL + +Q+K+ E +P T A + Y A +
Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR-ESMPYTNAVI 366
Query: 444 LETLRLFPPFPA-VLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWG-PDAAEYR 271
E R+ P V R D L+ +P+GT+ + + R W PD +
Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLAGYH--LPKGTMILTNLTALHRDPTEWATPDT--FN 422
Query: 270 PERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF---TAEQAELQ 103
P+ +L + AF+ FS G+RAC+G+ A L S +++ F E+ L+
Sbjct: 423 PDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLK 482
Query: 102 LKLDVVLRPASGHLLQV 52
++ + + P S L V
Sbjct: 483 FRMGITISPVSHRLCAV 499
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 57.6 bits (133), Expect = 5e-08
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 6/197 (3%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+ F ET +TTL +ALL + +Q+K+ E +P T A + Y A +
Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR-ESMPYTNAVI 366
Query: 444 LETLRLFPPFPA-VLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWG-PDAAEYR 271
E R+ P V R D L+ +P+GT+ + + R W PD +
Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLAGYH--LPKGTMILTNLTALHRDPTEWATPDT--FN 422
Query: 270 PERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF---TAEQAELQ 103
P+ +L + AF+ FS G+RAC+G+ A L S +++ F E+ L+
Sbjct: 423 PDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLK 482
Query: 102 LKLDVVLRPASGHLLQV 52
++ + + P S L V
Sbjct: 483 FRMGITISPVSHRLCAV 499
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 57.2 bits (132), Expect = 6e-08
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 1/146 (0%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHGLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ +P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRR 202
+ P R+ AP AQ + AFL FS G R
Sbjct: 431 FDPSRF-APGSAQHSHAFLPFSGGSR 455
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 57.2 bits (132), Expect = 6e-08
Identities = 48/176 (27%), Positives = 80/176 (45%), Gaps = 6/176 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLRLFPPFPAVL-RMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
A +LET R P P + +D L+ +P+ V+ + LW D +E
Sbjct: 370 AFILETFRHSPFLPFTIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPSE 426
Query: 276 YRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 427 FRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 57.2 bits (132), Expect = 6e-08
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 1/146 (0%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHGLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ +P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPKVW-PNLEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRR 202
+ P R+ AP AQ + AFL FS G R
Sbjct: 431 FDPSRF-APGSAQHSHAFLPFSGGSR 455
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 57.2 bits (132), Expect = 6e-08
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 6/197 (3%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+ F ET +TTL +ALL + +Q+K+ E +P T A + Y A +
Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIGQGQQPSTAAR-ESMPYTNAVI 366
Query: 444 LETLRLFPPFPA-VLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWG-PDAAEYR 271
E R+ P V R D L+ +P+GT+ + + R W PD +
Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLAGYH--LPKGTMILTNLTALHRDPTEWATPDT--FN 422
Query: 270 PERWLAPPHAQPA-AFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF---TAEQAELQ 103
P+ +L + AF+ FS G+RAC+G+ A L S +++ F E+ L+
Sbjct: 423 PDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLK 482
Query: 102 LKLDVVLRPASGHLLQV 52
++ + + P S L V
Sbjct: 483 FRMGITISPVSHRLCAV 499
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 56.0 bits (129), Expect = 1e-07
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 1/146 (0%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ +P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRR 202
+ P R+ AP AQ + AFL FS G R
Sbjct: 431 FDPFRF-APGSAQHSHAFLPFSGGSR 455
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 56.0 bits (129), Expect = 1e-07
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 1/146 (0%)
Frame = -3
Query: 636 EVDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
EVDT +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 314 EVDTFMFEGHDTTASGISWILYALATHPKHQERC-REEIHSLLGDGASITWNHLDQMPYT 372
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ E LRL+PP P + R + G+ +P+G + +S + ++W P+
Sbjct: 373 TMCIKEALRLYPPVPGIGRELSTPVTFPDGRS-LPKGIMVLLSIYGLHHNPKVW-PNPEV 430
Query: 276 YRPERWLAPPHAQPA-AFLAFSYGRR 202
+ P R+ AP AQ + AFL FS G R
Sbjct: 431 FDPFRF-APGSAQHSHAFLPFSGGSR 455
>AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2
protein.
Length = 516
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ V +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDVFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 7/177 (3%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
V+ + +TV T + ++L+ + +Q K+ E RP +D P L Y E
Sbjct: 311 VNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLE 369
Query: 453 ATVLETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAA 280
A +LET R F PF + +D L+ +P+ V+ + LW D +
Sbjct: 370 AFILETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPS 425
Query: 279 EYRPERWLAPPHA---QPAA--FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
E+RPER+L +P + + F G+R CIG+ A + LA +++LEF+
Sbjct: 426 EFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 482
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET + + + L + + ++ KLY E P T +D L EAT+ E LRL
Sbjct: 305 ETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRL 363
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLW-GPDAAEYRPERWLAP 250
P P +L ++ S G+ V +GT ++ + + W PD ++ PER+L P
Sbjct: 364 RPVAP-MLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPD--QFMPERFLNP 420
Query: 249 PHAQ----PAAFLAFSYGRRACIGKNYAMAILKTVLA 151
Q ++L F G R+CIG+ A L ++A
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET + + + L + + ++ KLY E P T +D L EAT+ E LRL
Sbjct: 305 ETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRL 363
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLW-GPDAAEYRPERWLAP 250
P P +L ++ S G+ V +GT ++ + + W PD ++ PER+L P
Sbjct: 364 RPVAP-MLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPD--QFMPERFLNP 420
Query: 249 PHAQ----PAAFLAFSYGRRACIGKNYAMAILKTVLA 151
Q ++L F G R+CIG+ A L ++A
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET + + + L + + ++ KLY E P T +D L EAT+ E LRL
Sbjct: 305 ETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRL 363
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLW-GPDAAEYRPERWLAP 250
P P +L ++ S G+ V +GT ++ + + W PD ++ PER+L P
Sbjct: 364 RPVAP-MLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPD--QFMPERFLNP 420
Query: 249 PHAQ----PAAFLAFSYGRRACIGKNYAMAILKTVLA 151
Q ++L F G R+CIG+ A L ++A
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET + + + L + + ++ KLY E P T +D L EAT+ E LRL
Sbjct: 305 ETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRL 363
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLW-GPDAAEYRPERWLAP 250
P P +L ++ S G+ V +GT ++ + + W PD ++ PER+L P
Sbjct: 364 RPVAP-MLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPD--QFMPERFLNP 420
Query: 249 PHAQ----PAAFLAFSYGRRACIGKNYAMAILKTVLA 151
Q ++L F G R+CIG+ A L ++A
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET + + + L + + ++ KLY E P T +D L EAT+ E LRL
Sbjct: 305 ETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRL 363
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLW-GPDAAEYRPERWLAP 250
P P +L ++ S G+ V +GT ++ + + W PD ++ PER+L P
Sbjct: 364 RPVAP-MLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPD--QFMPERFLNP 420
Query: 249 PHAQ----PAAFLAFSYGRRACIGKNYAMAILKTVLA 151
Q ++L F G R+CIG+ A L ++A
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET + + + L + + ++ KLY E P T +D L EAT+ E LRL
Sbjct: 305 ETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRL 363
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLW-GPDAAEYRPERWLAP 250
P P +L ++ S G+ V +GT ++ + + W PD ++ PER+L P
Sbjct: 364 RPVAP-MLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPD--QFMPERFLNP 420
Query: 249 PHAQ----PAAFLAFSYGRRACIGKNYAMAILKTVLA 151
Q ++L F G R+CIG+ A L ++A
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET + + + L + + ++ KLY E P T +D L EAT+ E LRL
Sbjct: 305 ETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRL 363
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLW-GPDAAEYRPERWLAP 250
P P +L ++ S G+ V +GT ++ + + W PD ++ PER+L P
Sbjct: 364 RPVAP-MLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPD--QFMPERFLNP 420
Query: 249 PHAQ----PAAFLAFSYGRRACIGKNYAMAILKTVLA 151
Q ++L F G R+CIG+ A L ++A
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET + + + L + + ++ KLY E P T +D L EAT+ E LRL
Sbjct: 305 ETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRL 363
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLW-GPDAAEYRPERWLAP 250
P P +L ++ S G+ V +GT ++ + + W PD ++ PER+L P
Sbjct: 364 RPVAP-MLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPD--QFMPERFLNP 420
Query: 249 PHAQ----PAAFLAFSYGRRACIGKNYAMAILKTVLA 151
Q ++L F G R+CIG+ A L ++A
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
ET + + + L + + ++ KLY E P T +D L EAT+ E LRL
Sbjct: 305 ETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRL 363
Query: 426 FPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLW-GPDAAEYRPERWLAP 250
P P +L ++ S G+ V +GT ++ + + W PD ++ PER+L P
Sbjct: 364 RPVAP-MLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPD--QFMPERFLNP 420
Query: 249 PHAQ----PAAFLAFSYGRRACIGKNYAMAILKTVLA 151
Q ++L F G R+CIG+ A L ++A
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMA 457
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 54.4 bits (125), Expect = 5e-07
Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 1/145 (0%)
Frame = -3
Query: 627 TVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEAT 448
T +F H+T A+ + + L + Q++ E +T L + Y
Sbjct: 1 TFMFEGHDTTASGISWILYALATHPKHQERC-REEIHGLLGDGASITWNHLDQMPYTTMC 59
Query: 447 VLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRP 268
+ E LRL+PP P + R + G+ +P+G +S + ++W P+ + P
Sbjct: 60 IKEALRLYPPVPGISRELSTPVTFPDGRS-LPKGITVMLSIYGLHHNPKVW-PNPEVFDP 117
Query: 267 ERWLAPPHAQPA-AFLAFSYGRRAC 196
R+ AP AQ + AFL FS G R C
Sbjct: 118 SRF-APGSAQHSHAFLPFSGGSRNC 141
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 54.4 bits (125), Expect = 5e-07
Identities = 33/121 (27%), Positives = 57/121 (47%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 162 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKA-PVTYDALVQMEYLDMVV 220
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 221 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 277
Query: 264 R 262
R
Sbjct: 278 R 278
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 54.4 bits (125), Expect = 5e-07
Identities = 33/121 (27%), Positives = 57/121 (47%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
++F ++T +TTL + + + ++Q KL E PVT L + Y + V
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKA-PVTYDALVQMEYLDMVV 360
Query: 444 LETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPE 265
ETLRLFP V R+ KD++++ +P+G V + + W + ++ PE
Sbjct: 361 NETLRLFPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPE 417
Query: 264 R 262
R
Sbjct: 418 R 418
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/169 (28%), Positives = 79/169 (46%), Gaps = 4/169 (2%)
Frame = -3
Query: 633 VDTVLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCE 454
+D V+ G ET + TL +A L++GR ++Q ++ E P D L Y
Sbjct: 291 LDMVMAGT-ETTSATLQWAALLMGRHPDVQGRVQEELDRVLGPGRTPRL-EDQQALPYTS 348
Query: 453 ATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGT--VCAVSAMVMGRARRLWGPDAA 280
A + E R P V R D QL G ++P+GT + ++++++ + W
Sbjct: 349 AVLHEVQRFITLLPHVPRCTAADTQL--GGFLLPKGTPVIPLLTSVLLDETQ--W-QTPG 403
Query: 279 EYRPERWL-APPH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVR 139
++ P +L A H + AFL FS GRR C+G+ A L + A ++
Sbjct: 404 QFNPGHFLDANGHFVKREAFLPFSAGRRVCVGERLARTELFLLFAGLLQ 452
>M12078-1|AAA52154.1| 192|Homo sapiens POR protein.
Length = 192
Score = 51.6 bits (118), Expect = 3e-06
Identities = 49/175 (28%), Positives = 80/175 (45%), Gaps = 9/175 (5%)
Frame = -3
Query: 621 LFGX-HETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATV 445
+FG +TV T + ++L+ + +Q K+ E RP +D P L Y EA +
Sbjct: 20 IFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL-SDRPQLPYLEAFI 78
Query: 444 LETLR--LFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
LET R F PF + +D L+ +P+ V+ + LW D +E+R
Sbjct: 79 LETFRHSSFLPF-TIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELW-EDPSEFR 134
Query: 270 PERWLAPPHA---QPAA---FLAFSYGRRACIGKNYAMAILKTVLASCVRELEFT 124
PER+L +P + + G+R CIG+ A + LA +++LEF+
Sbjct: 135 PERFLTADGTAINKPLSEKMMMLVGMGKRRCIGEVLAKWEIFLFLAILLQQLEFS 189
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 50.8 bits (116), Expect = 6e-06
Identities = 38/163 (23%), Positives = 72/163 (44%), Gaps = 3/163 (1%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
+T +L++ LL + + ++Q+K++ E P D + Y EAT++E RL
Sbjct: 355 DTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSL-TDKAQMPYTEATIMEVQRL 413
Query: 426 FPPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWLAP 250
P A+ M ++ L +P+GT+ + + R +W ++ P R+L
Sbjct: 414 TVVVPLAIPHMTSENTVLQG--YTIPKGTLILPNLWSVHRDPAIW-EKPEDFYPNRFLDD 470
Query: 249 PHA--QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF 127
+ F+ F G+R C+G+ A L + S ++ F
Sbjct: 471 QGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAF 513
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 50.8 bits (116), Expect = 6e-06
Identities = 38/163 (23%), Positives = 72/163 (44%), Gaps = 3/163 (1%)
Frame = -3
Query: 606 ETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYCEATVLETLRL 427
+T +L++ LL + + ++Q+K++ E P D + Y EAT++E RL
Sbjct: 355 DTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSL-TDKAQMPYTEATIMEVQRL 413
Query: 426 FPPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWLAP 250
P A+ M ++ L +P+GT+ + + R +W ++ P R+L
Sbjct: 414 TVVVPLAIPHMTSENTVLQG--YTIPKGTLILPNLWSVHRDPAIW-EKPEDFYPNRFLDD 470
Query: 249 PHA--QPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEF 127
+ F+ F G+R C+G+ A L + S ++ F
Sbjct: 471 QGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAF 513
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 50.4 bits (115), Expect = 7e-06
Identities = 44/148 (29%), Positives = 66/148 (44%), Gaps = 3/148 (2%)
Frame = -3
Query: 588 LVYALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGA--DLPHLRYCEATVLETLRLFPPF 415
L+ L + R+ N+Q L E A +LP LR A + ETLRL+P
Sbjct: 113 LLMTLFELARNPNVQQPLRQESLAPAASISEHPQKATTELPLLR---AALKETLRLYPVG 169
Query: 414 PAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYRPERWL-APPHAQ 238
+ R+ DL L + +P GT+ V +GR L+ P Y P+RWL +
Sbjct: 170 LILERVVSSDLVLQNYH--IPAGTLVRVFLYSLGRNPALF-PRPERYNPQRWLDIKGSGR 226
Query: 237 PAAFLAFSYGRRACIGKNYAMAILKTVL 154
+ F +G R C+G+ A A + +L
Sbjct: 227 NFYHVPFGFGMRQCLGRRLAEADMLLLL 254
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 49.2 bits (112), Expect = 2e-05
Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Frame = -3
Query: 480 DLPHLRYCEATVLETLRLFPPFP-AVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRAR 304
D H+ Y A + E R P V M +D+++ + +P+GT + + +
Sbjct: 368 DQVHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFR--IPKGTTLITNLSSVLKDE 425
Query: 303 RLWGPDAAEYRPERWL-APPH-AQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELE 130
+W + PE +L A H +P AFL FS GRRAC+G+ A L S ++
Sbjct: 426 AVW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 484
Query: 129 FT 124
F+
Sbjct: 485 FS 486
>AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein.
Length = 462
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/185 (21%), Positives = 85/185 (45%), Gaps = 3/185 (1%)
Frame = -3
Query: 630 DTVLFGXHETVATTLV--YALLMIGRDKNLQDKLYNEXXXXXXXXXRPVTGADLPHLRYC 457
D+++F + T + +A+ + + +Q KLY E PVT + LRYC
Sbjct: 269 DSMIFSLASCIITAKLCTWAICFLTTSEEVQKKLYEEINQVFGNG--PVTPEKIEQLRYC 326
Query: 456 EATVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAE 277
+ + ET+R P ++ +D++ + ++PR T+ + V+ + W P +
Sbjct: 327 QHVLCETVRTAKLTPVSAQL--QDIEGKIDRFIIPRETLVLYALGVVLQDPNTW-PSPHK 383
Query: 276 YRPERWLAPPHAQPAAFLAFSYGRRACIGKNYAMAILKTVLASCVRELEFTAEQAE-LQL 100
+ P+R+ + + L FS G + C +A + +L+ V+ L + + + ++
Sbjct: 384 FDPDRFDDELVMKTFSSLGFS-GTQECPELRFAYMVTTVLLSVLVKRLHLLSVEGQVIET 442
Query: 99 KLDVV 85
K ++V
Sbjct: 443 KYELV 447
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 48.8 bits (111), Expect = 2e-05
Identities = 47/159 (29%), Positives = 63/159 (39%), Gaps = 2/159 (1%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP--VTGADLPHLRYCEA 451
+L G ET A TL +A++ + +Q +L E V D L A
Sbjct: 288 LLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNA 347
Query: 450 TVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
T+ E LRL P P L SG + P GTV + +W E+
Sbjct: 348 TIAEVLRLRPVVPLALPHCTTRPSSISGYDI-PEGTVIIPNLQGAHLDETVW-ERPHEFW 405
Query: 270 PERWLAPPHAQPAAFLAFSYGRRACIGKNYAMAILKTVL 154
P+R+L P A LAF G R C+G+ A L VL
Sbjct: 406 PDRFLEPGKNSRA--LAFGCGARVCLGEPLARLELFVVL 442
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 48.8 bits (111), Expect = 2e-05
Identities = 47/159 (29%), Positives = 63/159 (39%), Gaps = 2/159 (1%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP--VTGADLPHLRYCEA 451
+L G ET A TL +A++ + +Q +L E V D L A
Sbjct: 288 LLIGGTETTANTLSWAVVFLFHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNA 347
Query: 450 TVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
T+ E LRL P P L SG + P GTV + +W E+
Sbjct: 348 TIAEVLRLRPVVPLALPHRTTRPSSISGYDI-PEGTVIIPNLQGAHLDETVW-ERPHEFW 405
Query: 270 PERWLAPPHAQPAAFLAFSYGRRACIGKNYAMAILKTVL 154
P+R+L P A LAF G R C+G+ A L VL
Sbjct: 406 PDRFLEPGKNSRA--LAFGCGARVCLGEPLARLELFVVL 442
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 48.4 bits (110), Expect = 3e-05
Identities = 47/159 (29%), Positives = 63/159 (39%), Gaps = 2/159 (1%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP--VTGADLPHLRYCEA 451
+L G ET A TL +A++ + +Q +L E V D L A
Sbjct: 289 LLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNA 348
Query: 450 TVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
T+ E LRL P P L SG + P GTV + +W E+
Sbjct: 349 TIAEVLRLRPVVPLALPHRTTRPSSISGYDI-PEGTVIIPNLQGAHLDETVW-ERPHEFW 406
Query: 270 PERWLAPPHAQPAAFLAFSYGRRACIGKNYAMAILKTVL 154
P+R+L P A LAF G R C+G+ A L VL
Sbjct: 407 PDRFLEPGKNSRA--LAFGCGARVCLGEPLARLELFVVL 443
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 48.4 bits (110), Expect = 3e-05
Identities = 47/159 (29%), Positives = 63/159 (39%), Gaps = 2/159 (1%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP--VTGADLPHLRYCEA 451
+L G ET A TL +A++ + +Q +L E V D L A
Sbjct: 289 LLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNA 348
Query: 450 TVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
T+ E LRL P P L SG + P GTV + +W E+
Sbjct: 349 TIAEVLRLRPVVPLALPHRTTRPSSISGYDI-PEGTVIIPNLQGAHLDETVW-ERPHEFW 406
Query: 270 PERWLAPPHAQPAAFLAFSYGRRACIGKNYAMAILKTVL 154
P+R+L P A LAF G R C+G+ A L VL
Sbjct: 407 PDRFLEPGKNSRA--LAFGCGARVCLGEPLARLELFVVL 443
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 48.4 bits (110), Expect = 3e-05
Identities = 47/159 (29%), Positives = 63/159 (39%), Gaps = 2/159 (1%)
Frame = -3
Query: 624 VLFGXHETVATTLVYALLMIGRDKNLQDKLYNEXXXXXXXXXRP--VTGADLPHLRYCEA 451
+L G ET A TL +A++ + +Q +L E V D L A
Sbjct: 289 LLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNA 348
Query: 450 TVLETLRLFPPFPAVLRMADKDLQLSSGKCVVPRGTVCAVSAMVMGRARRLWGPDAAEYR 271
T+ E LRL P P L SG + P GTV + +W E+
Sbjct: 349 TIAEVLRLRPVVPLALPHRTTRPSSISGYDI-PEGTVIIPNLQGAHLDETVW-ERPHEFW 406
Query: 270 PERWLAPPHAQPAAFLAFSYGRRACIGKNYAMAILKTVL 154
P+R+L P A LAF G R C+G+ A L VL
Sbjct: 407 PDRFLEPGKNSRA--LAFGCGARVCLGEPLARLELFVVL 443
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,640,035
Number of Sequences: 237096
Number of extensions: 2382359
Number of successful extensions: 11064
Number of sequences better than 10.0: 400
Number of HSP's better than 10.0 without gapping: 10446
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10820
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9813323168
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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