Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP13_FL5_E01
(918 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 66 2e-10
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 64 9e-10
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 64 9e-10
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 64 9e-10
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 64 9e-10
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 64 9e-10
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 64 9e-10
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 62 4e-09
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 62 4e-09
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 60 8e-09
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 60 1e-08
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 59 2e-08
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 59 2e-08
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 59 2e-08
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 59 2e-08
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 59 2e-08
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 59 2e-08
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 59 2e-08
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 57 1e-07
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 57 1e-07
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 57 1e-07
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 57 1e-07
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 57 1e-07
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 57 1e-07
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 57 1e-07
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 57 1e-07
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 57 1e-07
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 57 1e-07
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 57 1e-07
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 57 1e-07
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 57 1e-07
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 57 1e-07
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 57 1e-07
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 56 2e-07
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 56 2e-07
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 56 2e-07
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 56 2e-07
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 56 2e-07
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 56 2e-07
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 55 3e-07
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 55 3e-07
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 55 4e-07
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 55 4e-07
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 55 4e-07
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 55 4e-07
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 55 4e-07
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 54 5e-07
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 54 5e-07
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 54 5e-07
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 54 5e-07
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 54 5e-07
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 54 5e-07
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 54 7e-07
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 54 7e-07
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 54 7e-07
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 54 7e-07
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 54 7e-07
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 54 7e-07
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 54 7e-07
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 53 1e-06
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 53 1e-06
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 53 1e-06
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 53 1e-06
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 53 1e-06
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 53 1e-06
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 52 2e-06
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 52 2e-06
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 52 2e-06
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 52 2e-06
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 52 2e-06
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 52 2e-06
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 52 2e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 52 3e-06
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 52 3e-06
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 52 3e-06
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 52 3e-06
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 52 3e-06
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 52 3e-06
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 52 3e-06
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 52 3e-06
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 52 3e-06
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 52 4e-06
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 52 4e-06
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 52 4e-06
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 52 4e-06
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 52 4e-06
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 52 4e-06
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 52 4e-06
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 52 4e-06
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 52 4e-06
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 52 4e-06
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 52 4e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 51 5e-06
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 51 5e-06
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 51 5e-06
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 51 5e-06
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 51 7e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 50 9e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 50 9e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 50 9e-06
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 50 1e-05
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 48 5e-05
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 47 8e-05
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 47 1e-04
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 47 1e-04
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 47 1e-04
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 46 1e-04
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 46 1e-04
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 46 1e-04
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 46 1e-04
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 46 1e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 46 1e-04
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 46 1e-04
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 46 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 46 1e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 46 1e-04
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 46 1e-04
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 46 1e-04
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 46 1e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 46 1e-04
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 45 3e-04
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 45 3e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 44 6e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 44 6e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 44 6e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 44 6e-04
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 44 8e-04
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 44 8e-04
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 44 8e-04
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 44 8e-04
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 44 8e-04
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 44 0.001
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 44 0.001
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 44 0.001
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.002
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.002
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 43 0.002
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 43 0.002
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 42 0.002
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 42 0.003
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 42 0.003
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 42 0.004
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 42 0.004
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 41 0.005
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 41 0.005
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 41 0.005
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 41 0.005
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 41 0.005
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 41 0.005
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 40 0.010
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 40 0.010
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 40 0.010
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 39 0.022
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 31 7.7
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 31 7.7
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 31 7.7
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 31 7.7
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 31 7.7
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 65.7 bits (153), Expect = 2e-10
Identities = 43/159 (27%), Positives = 72/159 (45%), Gaps = 8/159 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 409
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 410 VSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V +NGSV W+ + +++ +P D CT KF S
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 172
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 63.7 bits (148), Expect = 9e-10
Identities = 44/160 (27%), Positives = 73/160 (45%), Gaps = 9/160 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V +NGSV W+ + +++ +P D CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 63.7 bits (148), Expect = 9e-10
Identities = 44/160 (27%), Positives = 73/160 (45%), Gaps = 9/160 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V +NGSV W+ + +++ +P D CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 63.7 bits (148), Expect = 9e-10
Identities = 44/160 (27%), Positives = 73/160 (45%), Gaps = 9/160 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V +NGSV W+ + +++ +P D CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 63.7 bits (148), Expect = 9e-10
Identities = 44/160 (27%), Positives = 73/160 (45%), Gaps = 9/160 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V +NGSV W+ + +++ +P D CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 63.7 bits (148), Expect = 9e-10
Identities = 44/160 (27%), Positives = 73/160 (45%), Gaps = 9/160 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V +NGSV W+ + +++ +P D CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 63.7 bits (148), Expect = 9e-10
Identities = 44/160 (27%), Positives = 73/160 (45%), Gaps = 9/160 (5%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 406
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V +NGSV W+ + +++ +P D CT KF S
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 173
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/140 (32%), Positives = 70/140 (50%), Gaps = 4/140 (2%)
Frame = +2
Query: 152 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 325
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 326 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 499
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 500 XTCTFKFXSRMHNSDXMGLR 559
CT F S ++S + L+
Sbjct: 163 QNCTMVFSSYSYDSSEVSLQ 182
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/140 (32%), Positives = 70/140 (50%), Gaps = 4/140 (2%)
Frame = +2
Query: 152 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 325
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 326 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDISTPISMQLDNWPNDM 499
++E +W PDVVLLN D AL VS++GSV W + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 500 XTCTFKFXSRMHNSDXMGLR 559
CT F S ++S + L+
Sbjct: 163 QNCTMVFSSYSYDSSEVSLQ 182
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 60.5 bits (140), Expect = 8e-09
Identities = 44/142 (30%), Positives = 71/142 (50%), Gaps = 6/142 (4%)
Frame = +2
Query: 152 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 325
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 326 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSWIKRLDISTPISMQLDNWPN 493
++E +W PDVVLLN G++ + VS++GSV W + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 494 DMXTCTFKFXSRMHNSDXMGLR 559
D CT F S ++S + L+
Sbjct: 161 DWQNCTMVFSSYSYDSSEVSLQ 182
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 59.7 bits (138), Expect = 1e-08
Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
D+VL N A T V +NGSV W+ + +++ +P D CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
V W + +M + +P D C+ KF S ++ + L
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDL 183
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
V W + +M + +P D C+ KF S ++ + L
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDL 148
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
V W + +M + +P D C+ KF S ++ + L
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDL 183
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
V W + +M + +P D C+ KF S ++ + L
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDL 183
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
V W + +M + +P D C+ KF S ++ + L
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDL 183
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
V W + +M + +P D C+ KF S ++ + L
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDL 183
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
V W + +M + +P D C+ KF S ++ + L
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDL 183
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 56.8 bits (131), Expect = 1e-07
Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G T L V SE +W PD+VL NA A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V W+ + S+ + +P D C KF S
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 177
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 148
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 56.8 bits (131), Expect = 1e-07
Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G T L V SE +W PD+VL NA A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V W+ + S+ + +P D C KF S
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 177
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 87 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 146
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 147 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 179
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 178
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 427
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 81 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 140
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
V+WI + + + +P D CT KF S
Sbjct: 141 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 173
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Frame = +2
Query: 122 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 286
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 287 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 463
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 464 ISMQLDNWPNDMXTCTFKFXS 526
++ + +P D+ C+ KF S
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Frame = +2
Query: 122 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 286
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 287 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 463
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 464 ISMQLDNWPNDMXTCTFKFXS 526
++ + +P D+ C+ KF S
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Frame = +2
Query: 122 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 286
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 287 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 463
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 464 ISMQLDNWPNDMXTCTFKFXS 526
++ + +P D+ C+ KF S
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Frame = +2
Query: 122 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 286
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 287 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 463
WN ++G V S+ +W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 464 ISMQLDNWPNDMXTCTFKFXS 526
++ + +P D+ C+ KF S
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 55.6 bits (128), Expect = 2e-07
Identities = 33/130 (25%), Positives = 66/130 (50%), Gaps = 3/130 (2%)
Frame = +2
Query: 164 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 337
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 338 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTF 514
+W P++VL N G Y V GSV+W+ + ++++ +P D C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 515 KFXSRMHNSD 544
F S+ +N++
Sbjct: 165 IFRSQTYNAE 174
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 55.6 bits (128), Expect = 2e-07
Identities = 33/130 (25%), Positives = 66/130 (50%), Gaps = 3/130 (2%)
Frame = +2
Query: 164 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 337
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 338 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTF 514
+W P++VL N G Y V GSV+W+ + ++++ +P D C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 515 KFXSRMHNSD 544
F S+ +N++
Sbjct: 165 IFRSQTYNAE 174
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 55.2 bits (127), Expect = 3e-07
Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 286
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 287 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDIS 457
W+ ++ G V S +WRPD+VL N + AL VS +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 458 TPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLR 559
+ S+ + +P D C+ F S+ ++++ + L+
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 55.2 bits (127), Expect = 3e-07
Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 286
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 287 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSWIKRLDIS 457
W+ ++ G V S +WRPD+VL N + AL VS +G + W+
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 458 TPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLR 559
+ S+ + +P D C+ F S+ ++++ + L+
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQ 184
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 54.8 bits (126), Expect = 4e-07
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 10/154 (6%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 259
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 260 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 424
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
++W + M + +P D C+ KF S
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 54.8 bits (126), Expect = 4e-07
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 10/154 (6%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 259
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 260 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 424
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
++W + M + +P D C+ KF S
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 54.8 bits (126), Expect = 4e-07
Identities = 34/141 (24%), Positives = 63/141 (44%), Gaps = 6/141 (4%)
Frame = +2
Query: 122 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 286
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 287 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSWIKRLDISTP 463
WN ++G V S+ W PD+VL + A + + + NG+V+W + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 464 ISMQLDNWPNDMXTCTFKFXS 526
++ + +P D+ C+ KF S
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGS 190
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 54.8 bits (126), Expect = 4e-07
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 10/154 (6%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 259
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 260 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 424
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
++W + M + +P D C+ KF S
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 54.8 bits (126), Expect = 4e-07
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 10/154 (6%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 259
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 260 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 424
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
++W + M + +P D C+ KF S
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGS 178
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 10/178 (5%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 217
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 218 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 394
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 395 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
A+ + + G ++W + + + ++P D C+ K + ++ + +
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAI 178
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 10/178 (5%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 217
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 218 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 394
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 395 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
A+ + + G ++W + + + ++P D C+ K + ++ + +
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAI 178
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 10/178 (5%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 217
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 218 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 394
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 395 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
A+ + + G ++W + + + ++P D C+ K + ++ + +
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAI 178
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 5/96 (5%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSN 418
L+ W D +L WN +G + ++ V ++++W+PD+VL N A GD+ + +A +
Sbjct: 84 LKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYNNA---VGDFQVTTKTKALLKY 140
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
G V+WI + + + +P D CT KF S
Sbjct: 141 TGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGS 176
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 10/178 (5%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 217
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 218 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 394
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 395 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
A+ + + G ++W + + + ++P D C+ K + ++ + +
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAI 178
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 10/178 (5%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NI 217
+ LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 4 WPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINV 63
Query: 218 RESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDY 394
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+
Sbjct: 64 DEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDF 120
Query: 395 AL----RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
A+ + + G ++W + + + ++P D C+ K + ++ + +
Sbjct: 121 AIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAI 178
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 54.0 bits (124), Expect = 7e-07
Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 451
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 452 ISTPISMQLDNWPNDMXTCTFKFXS 526
+ S+ + +P D CT KF S
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 54.0 bits (124), Expect = 7e-07
Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 451
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 452 ISTPISMQLDNWPNDMXTCTFKFXS 526
+ S+ + +P D CT KF S
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 54.0 bits (124), Expect = 7e-07
Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 451
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 452 ISTPISMQLDNWPNDMXTCTFKFXS 526
+ S+ + +P D CT KF S
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGS 156
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 54.0 bits (124), Expect = 7e-07
Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 451
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 452 ISTPISMQLDNWPNDMXTCTFKFXS 526
+ S+ + +P D CT KF S
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 54.0 bits (124), Expect = 7e-07
Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 451
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 452 ISTPISMQLDNWPNDMXTCTFKFXS 526
+ S+ + +P D CT KF S
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 54.0 bits (124), Expect = 7e-07
Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 451
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 452 ISTPISMQLDNWPNDMXTCTFKFXS 526
+ S+ + +P D CT KF S
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 54.0 bits (124), Expect = 7e-07
Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Frame = +2
Query: 122 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 286
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 287 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSWIKRLD 451
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V W
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 452 ISTPISMQLDNWPNDMXTCTFKFXS 526
+ S+ + +P D CT KF S
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 53.2 bits (122), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
+ K + + + ++ + +P D CT F S ++ D M
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 53.2 bits (122), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
+ K + + + ++ + +P D CT F S ++ D M
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 119
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 53.2 bits (122), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
+ K + + + ++ + +P D CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 53.2 bits (122), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
+ K + + + ++ + +P D CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 53.2 bits (122), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
+ K + + + ++ + +P D CT F S ++ D M
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 205
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 53.2 bits (122), Expect = 1e-06
Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 4/162 (2%)
Frame = +2
Query: 53 YXFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-NIRES 226
+ L C+ A+ E L+ S R + S++V V L + L ++ E
Sbjct: 14 FGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHER 73
Query: 227 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYAL 400
E + L W D RL+W E+ + S+ +W PDVVL N A +
Sbjct: 74 EQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYS 133
Query: 401 RARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 134 NAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 3/120 (2%)
Frame = +2
Query: 176 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 349
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 350 DVVLLNAA-ATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
DVVL N A + A VS +GS+ W+ + +++ ++P D CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +2
Query: 146 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 307
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 308 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 484
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 485 WPNDMXTCTFKFXSRMHNSDXMGL 556
+P D C+ KF S + + + L
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEITL 181
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 52.0 bits (119), Expect = 3e-06
Identities = 41/181 (22%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Frame = +2
Query: 44 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 208
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 209 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 376
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 377 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMG 553
+ + + +G ++W + + + +P D C F S +N + +
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 554 L 556
+
Sbjct: 185 I 185
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 52.0 bits (119), Expect = 3e-06
Identities = 41/181 (22%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Frame = +2
Query: 44 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 208
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 209 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 376
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 377 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMG 553
+ + + +G ++W + + + +P D C F S +N + +
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 554 L 556
+
Sbjct: 185 I 185
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +2
Query: 146 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 307
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 308 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 484
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 485 WPNDMXTCTFKFXSRMHNSDXMGL 556
+P D C+ KF S + + + L
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEITL 181
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +2
Query: 146 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 307
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 308 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 484
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 485 WPNDMXTCTFKFXSRMHNSDXMGL 556
+P D C+ KF S + + + L
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEITL 181
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 52.0 bits (119), Expect = 3e-06
Identities = 41/181 (22%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Frame = +2
Query: 44 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 208
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 209 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 376
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 377 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMG 553
+ + + +G ++W + + + +P D C F S +N + +
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 554 L 556
+
Sbjct: 185 I 185
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 52.0 bits (119), Expect = 3e-06
Identities = 41/181 (22%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Frame = +2
Query: 44 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 208
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 209 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 376
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 377 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMG 553
+ + + +G ++W + + + +P D C F S +N + +
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 554 L 556
+
Sbjct: 185 I 185
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 52.0 bits (119), Expect = 3e-06
Identities = 41/181 (22%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Frame = +2
Query: 44 YSCYXFLLTCAIAS---AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRH 208
+SC F AS AAE + + + L Y P D+ V+N+TL +
Sbjct: 5 HSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITL 64
Query: 209 ANIRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAA 376
+ I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 65 SQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKAD 124
Query: 377 TTAGD-YALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMG 553
+ + + +G ++W + + + +P D C F S +N + +
Sbjct: 125 DESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
Query: 554 L 556
+
Sbjct: 185 I 185
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 52.0 bits (119), Expect = 3e-06
Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Frame = +2
Query: 146 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 307
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 308 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSWIKRLDISTPISMQLDN 484
S + + +W P++VL N + Y+ V + G V W+ + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 485 WPNDMXTCTFKFXSRMHNSDXMGL 556
+P D C+ KF S + + + L
Sbjct: 158 FPFDWQNCSLKFSSLKYTAKEITL 181
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 10/178 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSD 544
++ R+ +G+V + R+ + M L +P D CT + S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 186
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 10/178 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSD 544
++ R+ +G+V + R+ + M L +P D CT + S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 186
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 10/178 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSD 544
++ R+ +G+V + R+ + M L +P D CT + S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 186
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 51.6 bits (118), Expect = 4e-06
Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
+ K + +++ ++ + +P D CTF F S ++ D M
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSM 190
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 10/178 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSD 544
++ R+ +G+V + R+ + M L +P D CT + S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 186
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 10/178 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSD 544
++ R+ +G+V + R+ + M L +P D CT + S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 186
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 51.6 bits (118), Expect = 4e-06
Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 10/178 (5%)
Frame = +2
Query: 41 YYSCYXFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHL 202
Y+ + F L A A + +++SL+ +D LL YD PD + V + + +
Sbjct: 9 YFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDI 68
Query: 203 RHAN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAAT 379
+ + E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 69 ASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKS 128
Query: 380 TAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSD 544
++ R+ +G+V + R+ + M L +P D CT + S + +D
Sbjct: 129 FVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 186
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 51.6 bits (118), Expect = 4e-06
Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 10/167 (5%)
Frame = +2
Query: 89 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 253
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 254 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 418
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLR 559
+G+V W + + + +P D C F S H + +R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 51.6 bits (118), Expect = 4e-06
Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 10/167 (5%)
Frame = +2
Query: 89 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 253
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 254 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 418
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLR 559
+G+V W + + + +P D C F S H + +R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 51.6 bits (118), Expect = 4e-06
Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 10/167 (5%)
Frame = +2
Query: 89 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 253
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 254 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 418
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLR 559
+G+V W + + + +P D C F S H + +R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 51.6 bits (118), Expect = 4e-06
Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 10/167 (5%)
Frame = +2
Query: 89 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 253
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 254 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 418
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 419 NGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLR 559
+G+V W + + + +P D C F S H + +R
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR 185
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 51.2 bits (117), Expect = 5e-06
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 7/133 (5%)
Frame = +2
Query: 62 LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RES 226
LL A+ A+ N L+ D L+ YD P + VVN++L L N+ E
Sbjct: 11 LLLLAVCLGAQGRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNER 68
Query: 227 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TAGDYAL 400
E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + + L
Sbjct: 69 EEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEIDL 128
Query: 401 RARVSNNGSVSWI 439
+ + S+ WI
Sbjct: 129 QLSQEDGQSIEWI 141
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 51.2 bits (117), Expect = 5e-06
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Frame = +2
Query: 248 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 424
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
+ + K + + + ++ + +P D CT F S ++ D M
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 190
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 51.2 bits (117), Expect = 5e-06
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Frame = +2
Query: 248 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 424
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
+ + K + + + ++ + +P D CT F S ++ D M
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSM 175
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 51.2 bits (117), Expect = 5e-06
Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 430
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 431 SWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
+ K + +++ + + +P D CTF F S ++ D M
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVDSM 190
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 50.8 bits (116), Expect = 7e-06
Identities = 36/164 (21%), Positives = 73/164 (44%), Gaps = 7/164 (4%)
Frame = +2
Query: 86 AAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD-- 253
AAE + + + L Y P D+ V+N+TL + + I++ + +IL
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 254 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGD-YALRARVSNNG 424
++ W D L+W+ ++ G + + S+ +WRPD+VL N A + + + +G
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDG 135
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGL 556
++W + + + +P D C F S +N + + +
Sbjct: 136 LITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDI 179
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 50.4 bits (115), Expect = 9e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 434 WIKRLDISTPISMQLDNWPNDMXTCTFKF 520
L T + +L ++P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.4 bits (115), Expect = 9e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 434 WIKRLDISTPISMQLDNWPNDMXTCTFKF 520
L T + +L ++P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 50.4 bits (115), Expect = 9e-06
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 434 WIKRLDISTPISMQLDNWPNDMXTCTFKF 520
L T + +L ++P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/89 (29%), Positives = 42/89 (47%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 433
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 434 WIKRLDISTPISMQLDNWPNDMXTCTFKF 520
L T + +L ++P D C+ F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSF 174
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 48.0 bits (109), Expect = 5e-05
Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 1/111 (0%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAG 388
N+ E + + W D+ L WN ++ T L + ++ +W PD+++
Sbjct: 72 NVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS 131
Query: 389 DYALRARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNS 541
+ + G V K L + T S+ + N+P D+ C+ F S +H S
Sbjct: 132 PNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTS 182
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 47.2 bits (107), Expect = 8e-05
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 7/167 (4%)
Frame = +2
Query: 65 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 232
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 233 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 403
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 404 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSD 544
R+ +G+V + R+ + M L +P D CT + S + +D
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 187
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 46.8 bits (106), Expect = 1e-04
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 46.8 bits (106), Expect = 1e-04
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 2/114 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLRXXTXRIYRYV 589
++ + + + +P D+ C KF S + + L+ I Y+
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYI 168
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 2/114 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLRXXTXRIYRYV 589
++ + + + +P D+ C KF S + + L+ I Y+
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYI 191
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 2/114 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLRXXTXRIYRYV 589
++ + + + +P D+ C KF S + + L+ I Y+
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYI 191
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 46.4 bits (105), Expect = 1e-04
Identities = 38/167 (22%), Positives = 68/167 (40%), Gaps = 7/167 (4%)
Frame = +2
Query: 65 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 232
+ C S E N + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 233 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 403
+ Q +W DKRLS++ + +++LW PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 404 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSD 544
R+ +G+V + R+ + M L +P D CT + S + +D
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 187
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 2/114 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLRXXTXRIYRYV 589
++ + + + +P D+ C KF S + + L+ I Y+
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYI 191
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 7/155 (4%)
Frame = +2
Query: 107 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 274
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 275 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 445
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 446 LDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
L I+ +QL N+P D +C F S + + M
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 74 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 232
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 233 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 394
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 2/114 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLRXXTXRIYRYV 589
++ + + + +P D+ C KF S + + L+ I Y+
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYI 191
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 7/155 (4%)
Frame = +2
Query: 107 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 274
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 45 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 104
Query: 275 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 445
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 105 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 164
Query: 446 LDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
L I+ +QL N+P D +C F S + + M
Sbjct: 165 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 199
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 7/155 (4%)
Frame = +2
Query: 107 TSLSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHAN-IRESESTVRILADLQMNWID 274
T ++L+++ LL YD++ PD I V+++ +++ + +I W D
Sbjct: 27 TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTD 86
Query: 275 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 445
RL +N+ + +W PD + N+ A R+ N+G + + R
Sbjct: 87 SRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLR 146
Query: 446 LDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXM 550
L I+ +QL N+P D +C F S + + M
Sbjct: 147 LTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEM 181
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N D R+S NG V + RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLRXXTXRIYRYV 589
++ + + + +P D+ C KF S + + L+ I Y+
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYI 191
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Frame = +2
Query: 254 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 427
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 428 VSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSDXMGLRXXTXRIYRYV 589
++ + + + +P D+ C KF S + + L+ I Y+
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYI 191
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 262
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 263 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 433
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 434 WIKRLDISTPISMQLDNWPNDMXTC 508
+ RL + S+ L +P D C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 262
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 263 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 433
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 434 WIKRLDISTPISMQLDNWPNDMXTC 508
+ RL + S+ L +P D C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 262
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 263 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 433
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 434 WIKRLDISTPISMQLDNWPNDMXTC 508
+ RL + S+ L +P D C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/145 (23%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 95 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 262
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 263 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 433
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 434 WIKRLDISTPISMQLDNWPNDMXTC 508
+ RL + S+ L +P D C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 44.0 bits (99), Expect = 8e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 110 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 277
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 278 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 448
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 449 DISTPISMQLDNWPNDMXTCTFKFXS 526
I+ M+L N+P D C KF S
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.0 bits (99), Expect = 8e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 110 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 277
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 278 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 448
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 449 DISTPISMQLDNWPNDMXTCTFKFXS 526
I+ M+L N+P D C KF S
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.0 bits (99), Expect = 8e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 110 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 277
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 278 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 448
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 449 DISTPISMQLDNWPNDMXTCTFKFXS 526
I+ M+L N+P D C KF S
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.0 bits (99), Expect = 8e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 110 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 277
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 278 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 448
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 449 DISTPISMQLDNWPNDMXTCTFKFXS 526
I+ M+L N+P D C KF S
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 44.0 bits (99), Expect = 8e-04
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 110 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 277
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 278 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSWIKRL 448
RL + S + ++W PD N + A + R+ NG++ + RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 449 DISTPISMQLDNWPNDMXTCTFKFXS 526
I+ M+L N+P D C KF S
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 7/147 (4%)
Frame = +2
Query: 125 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 292
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 293 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 463
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 464 ISMQLDNWPNDMXTCTFKFXSRMHNSD 544
M L +P D C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 7/147 (4%)
Frame = +2
Query: 125 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 292
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 293 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 463
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 464 ISMQLDNWPNDMXTCTFKFXSRMHNSD 544
M L +P D C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 7/147 (4%)
Frame = +2
Query: 125 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 292
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 293 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTP 463
++LW PD ++NA + D + R+ +G + + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 464 ISMQLDNWPNDMXTCTFKFXSRMHNSD 544
M L +P D C S ++S+
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSE 190
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 9/147 (6%)
Frame = +2
Query: 113 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 274
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 275 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 445
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 446 LDISTPISMQLDNWPNDMXTCTFKFXS 526
L I +QL N+P D +C +F S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSS 210
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 9/147 (6%)
Frame = +2
Query: 113 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 274
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 275 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 445
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 446 LDISTPISMQLDNWPNDMXTCTFKFXS 526
L I +QL N+P D +C +F S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSS 210
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 9/147 (6%)
Frame = +2
Query: 113 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 274
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 275 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 445
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 446 LDISTPISMQLDNWPNDMXTCTFKFXS 526
L I +QL N+P D +C +F S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSS 210
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 9/147 (6%)
Frame = +2
Query: 113 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 274
+++++++LL YD + PD + +++ +++ N E T+ I W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIF--FAQTWYD 123
Query: 275 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 445
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLR 183
Query: 446 LDISTPISMQLDNWPNDMXTCTFKFXS 526
L I +QL N+P D +C +F S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSS 210
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 42.3 bits (95), Expect = 0.002
Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 15/178 (8%)
Frame = +2
Query: 38 LYYSCYXFLLTCAIASAAEC-ENAT---SLSLMIDSLLAT---YDRESPPDSK-IVVNLT 193
LY S + A + AE +AT S S +D L+ YD P+ K VN++
Sbjct: 9 LYLSGAIVFFSLAASKEAEAARSATKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVS 68
Query: 194 LHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVL 361
++ +I E+ R+ L+ W D RL++N S + +W+PD+
Sbjct: 69 CNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFF 128
Query: 362 LNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
N + R+S NG+V + R+ ++ M L N+P D+ TC + S
Sbjct: 129 ANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 41.9 bits (94), Expect = 0.003
Identities = 37/147 (25%), Positives = 66/147 (44%), Gaps = 9/147 (6%)
Frame = +2
Query: 113 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRH---ANIRESESTVRILADLQMNWID 274
+++++++LL YD + PD + +++ +++ N E T+ I QM W D
Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFF-AQM-WYD 123
Query: 275 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL---RARVSNNGSVSWIKR 445
+RL +N+ ++W PD N+ A R+ N+G V + R
Sbjct: 124 RRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLR 183
Query: 446 LDISTPISMQLDNWPNDMXTCTFKFXS 526
L I +QL N+P D +C +F S
Sbjct: 184 LTIDAECQLQLHNFPMDEHSCPLEFSS 210
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 41.9 bits (94), Expect = 0.003
Identities = 37/167 (22%), Positives = 68/167 (40%), Gaps = 7/167 (4%)
Frame = +2
Query: 65 LTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESES 232
+ C S E N + + +D LL YD PD + V + + + + + E
Sbjct: 21 MVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNM 80
Query: 233 TVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR--- 403
+ Q +W DKRLS++ + +++L PD LN + ++
Sbjct: 81 DYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 404 ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXSRMHNSD 544
R+ +G+V + R+ + M L +P D CT + S + +D
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 187
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 41.5 bits (93), Expect = 0.004
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 388
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 389 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
+ R+S NG+V + R+ ++ M L N+P D+ TC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 41.5 bits (93), Expect = 0.004
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +2
Query: 212 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 388
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 389 DYALR---ARVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
+ R+S NG+V + R+ ++ M L N+P D+ TC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
+V + R+ + +M L +P D TC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
+V + R+ + +M L +P D TC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
+V + R+ + +M L +P D TC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
+V + R+ + +M L +P D TC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
+V + R+ + +M L +P D TC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 41.1 bits (92), Expect = 0.005
Identities = 36/147 (24%), Positives = 64/147 (43%), Gaps = 9/147 (6%)
Frame = +2
Query: 113 LSLMIDSLLATYDRESPPDSKI---VVNLTLHLRHANIRES---ESTVRILADLQMNWID 274
++ +++SLL YD + PD + V+ +++ + E T+ I+ W D
Sbjct: 64 ITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDII--FAQTWFD 121
Query: 275 KRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKR 445
RL +N+ ++W PD N+ + A R+ N+G V + R
Sbjct: 122 SRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLR 181
Query: 446 LDISTPISMQLDNWPNDMXTCTFKFXS 526
L I+ +QL N+P D +C +F S
Sbjct: 182 LTINAECYLQLHNFPMDEHSCPLEFSS 208
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 41.1 bits (92), Expect = 0.005
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N + R+ NG+V + RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 41.1 bits (92), Expect = 0.005
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 92 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 256
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 257 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 424
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 425 SVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
+V + R+ + +M L +P D TC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 40.3 bits (90), Expect = 0.010
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 40.3 bits (90), Expect = 0.010
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 40.3 bits (90), Expect = 0.010
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 146 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 313
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 314 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSWIKRLDISTPISMQLD 481
S + +W+PD+ N + R+ NG+V + RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 482 NWPNDMXTCTFKFXS 526
N+P D+ TC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 39.1 bits (87), Expect = 0.022
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Frame = +2
Query: 239 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 406
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 407 RVSNNGSVSWIKRLDISTPISMQLDNWPNDMXTCTFKFXS 526
R+S NG+V + R+ ++ M L N+P D+ TC + S
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 103
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.7 bits (66), Expect = 7.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 287 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 448
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 287 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 448
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.7 bits (66), Expect = 7.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 287 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 448
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 343
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.7 bits (66), Expect = 7.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 287 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 448
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 364
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.7 bits (66), Expect = 7.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Frame = +2
Query: 287 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNN-GSVSWIKRL 448
W +GEW C+ + + ++V+L T+ Y RV+NN G W + L
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLE----TSASYCPAERVANNRGDFRWPRTL 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 121,208,962
Number of Sequences: 237096
Number of extensions: 2833139
Number of successful extensions: 8029
Number of sequences better than 10.0: 163
Number of HSP's better than 10.0 without gapping: 6058
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7864
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11936890730
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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