Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP12_FL5_I08
(816 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 53 1e-06
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 52 2e-06
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 52 2e-06
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 52 2e-06
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 52 2e-06
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 52 2e-06
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 51 4e-06
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 51 4e-06
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 51 4e-06
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 51 4e-06
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 51 4e-06
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 51 4e-06
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 51 4e-06
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 48 4e-05
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 48 4e-05
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 47 7e-05
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 47 7e-05
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 46 1e-04
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 46 1e-04
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 46 1e-04
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 46 1e-04
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 46 1e-04
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 46 1e-04
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 46 1e-04
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 46 2e-04
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 46 2e-04
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 46 2e-04
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 46 2e-04
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 46 2e-04
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 46 2e-04
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 46 2e-04
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 46 2e-04
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 46 2e-04
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 46 2e-04
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 45 3e-04
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 45 3e-04
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 45 4e-04
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 45 4e-04
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 45 4e-04
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 45 4e-04
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 44 7e-04
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 44 7e-04
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 44 7e-04
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 44 7e-04
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 43 0.001
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 43 0.001
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 43 0.001
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 43 0.001
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 43 0.001
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 43 0.001
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 43 0.001
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 43 0.001
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 43 0.001
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 43 0.001
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 43 0.001
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 43 0.001
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 43 0.002
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 43 0.002
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 43 0.002
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 43 0.002
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 43 0.002
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 43 0.002
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 43 0.002
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 42 0.002
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 42 0.002
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 42 0.002
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 42 0.002
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 42 0.002
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 42 0.002
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 42 0.002
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 42 0.003
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 42 0.003
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 42 0.003
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 42 0.003
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 41 0.006
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 41 0.006
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 41 0.006
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 41 0.006
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 41 0.006
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 41 0.006
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 41 0.006
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 39 0.019
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 39 0.019
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 39 0.019
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 39 0.019
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 39 0.019
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 38 0.033
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 38 0.033
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 38 0.033
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 38 0.033
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 38 0.033
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 38 0.033
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 38 0.033
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 37 0.10
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 36 0.13
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 36 0.13
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 36 0.13
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 36 0.13
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 36 0.13
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 36 0.18
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 36 0.23
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 36 0.23
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 36 0.23
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 36 0.23
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 36 0.23
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 36 0.23
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 35 0.31
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 35 0.31
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 35 0.31
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 35 0.40
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 35 0.40
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 34 0.71
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 34 0.71
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 34 0.71
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 34 0.71
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 32 2.2
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 32 2.2
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 31 3.8
U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated prot... 31 5.0
CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein. 31 5.0
BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1, ... 31 5.0
AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens ... 31 5.0
BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein. 30 8.7
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 30 8.7
AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein. 30 8.7
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 30 8.7
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 30 8.7
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 30 8.7
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 53.2 bits (122), Expect = 1e-06
Identities = 40/145 (27%), Positives = 66/145 (45%), Gaps = 8/145 (5%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLH 213
L+LF+L A+ C A + ++D LL Y+ R + S+++ + L L
Sbjct: 7 LVLFFL-----VALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLS 61
Query: 214 LRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 387
L ++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N
Sbjct: 62 LAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNND 121
Query: 388 ATTXGDYALRARVSNNGSXSWXKXA 462
T V +NGS W A
Sbjct: 122 GTYEVSVYTNLIVRSNGSVLWLPPA 146
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 234
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYA 411
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 412 L 414
+
Sbjct: 122 I 122
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 234
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYA 411
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 412 L 414
+
Sbjct: 122 I 122
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 234
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYA 411
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 412 L 414
+
Sbjct: 122 I 122
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 234
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYA 411
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 412 L 414
+
Sbjct: 122 I 122
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 52.4 bits (120), Expect = 2e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHA---NIR 234
P LL ++ SA + + ++ L Y P D + VV +T+ L+ N+
Sbjct: 5 PLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVD 64
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYA 411
E V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A
Sbjct: 65 EVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFA 121
Query: 412 L 414
+
Sbjct: 122 I 122
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLH 213
L+LF+L A+ C A + ++D LL Y+ R + S+++ + L L
Sbjct: 7 LVLFFL-----VALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLS 61
Query: 214 LRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NA 384
L ++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA
Sbjct: 62 LAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNA 121
Query: 385 AATTXGDYALRARVSNNGSXSWXKXA 462
T V +NGS W A
Sbjct: 122 DGTYEVSVYTNLIVRSNGSVLWLPPA 147
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLH 213
L+LF+L A+ C A + ++D LL Y+ R + S+++ + L L
Sbjct: 7 LVLFFL-----VALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLS 61
Query: 214 LRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NA 384
L ++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA
Sbjct: 62 LAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNA 121
Query: 385 AATTXGDYALRARVSNNGSXSWXKXA 462
T V +NGS W A
Sbjct: 122 DGTYEVSVYTNLIVRSNGSVLWLPPA 147
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLH 213
L+LF+L A+ C A + ++D LL Y+ R + S+++ + L L
Sbjct: 7 LVLFFL-----VALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLS 61
Query: 214 LRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NA 384
L ++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA
Sbjct: 62 LAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNA 121
Query: 385 AATTXGDYALRARVSNNGSXSWXKXA 462
T V +NGS W A
Sbjct: 122 DGTYEVSVYTNLIVRSNGSVLWLPPA 147
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 51.2 bits (117), Expect = 4e-06
Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 7/134 (5%)
Frame = +1
Query: 70 PFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---R 234
P LL +A + ++ L+ YD + P + VVN++L L N+
Sbjct: 7 PLLLLLLLAVCLGAQGRNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLN 66
Query: 235 ESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT-TXGDY 408
E E + ++M W D RL W+ ++ G V S +WRPD+VL N + T + +
Sbjct: 67 EREEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQTYSTNEI 126
Query: 409 ALRARVSNNGSXSW 450
L+ + S W
Sbjct: 127 DLQLSQEDGQSIEW 140
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLH 213
L+LF+L A+ C A + ++D LL Y+ R + S+++ + L L
Sbjct: 7 LVLFFL-----VALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLS 61
Query: 214 LRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NA 384
L ++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA
Sbjct: 62 LAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNA 121
Query: 385 AATTXGDYALRARVSNNGSXSWXKXA 462
T V +NGS W A
Sbjct: 122 DGTYEVSVYTNLIVRSNGSVLWLPPA 147
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLH 213
L+LF+L A+ C A + ++D LL Y+ R + S+++ + L L
Sbjct: 7 LVLFFL-----VALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLS 61
Query: 214 LRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NA 384
L ++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA
Sbjct: 62 LAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNA 121
Query: 385 AATTXGDYALRARVSNNGSXSWXKXA 462
T V +NGS W A
Sbjct: 122 DGTYEVSVYTNLIVRSNGSVLWLPPA 147
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLH 213
L+LF+L A+ C A + ++D LL Y+ R + S+++ + L L
Sbjct: 7 LVLFFL-----VALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLS 61
Query: 214 LRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NA 384
L ++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL NA
Sbjct: 62 LAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNA 121
Query: 385 AATTXGDYALRARVSNNGSXSWXKXA 462
T V +NGS W A
Sbjct: 122 DGTYEVSVYTNLIVRSNGSVLWLPPA 147
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 8/123 (6%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLH 213
L+LF+L A+ C A + ++D LL Y+ R + S+++ + L L
Sbjct: 7 LVLFFL-----VALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLS 61
Query: 214 LRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 387
L ++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N +
Sbjct: 62 LAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKS 121
Query: 388 ATT 396
T
Sbjct: 122 LRT 124
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 8/123 (6%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLL--ATYD---RDSPPDSKIV-VNLTLH 213
L+LF+L A+ C A + ++D LL Y+ R + S+++ + L L
Sbjct: 7 LVLFFL-----VALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLS 61
Query: 214 LRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 387
L ++ E E + L+ W D RL+WN+ + G + + ++R+W PD+VL N +
Sbjct: 62 LAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKS 121
Query: 388 ATT 396
T
Sbjct: 122 LRT 124
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 47.2 bits (107), Expect = 7e-05
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 187 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 360
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 361 PDVVLLNAAATTXGDYAL--RARVSNNGSXSW 450
PDVVLLN D AL VS++GS W
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRW 141
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 47.2 bits (107), Expect = 7e-05
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 187 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 360
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 361 PDVVLLNAAATTXGDYAL--RARVSNNGSXSW 450
PDVVLLN D AL VS++GS W
Sbjct: 111 PDVVLLNNNDGNF-DVALDISVVVSSDGSVRW 141
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/144 (27%), Positives = 60/144 (41%), Gaps = 7/144 (4%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP----DSKIVVNLTLHLR 219
LI+ +P T S AE E+A ++ L Y + P + I V L +
Sbjct: 9 LIVLGIPSSATTGFNSIAENEDA-----LLRHLFQGYQKWVRPVLHSNDTIKVYFGLKIS 63
Query: 220 H-ANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAA 390
++ E + L+ W D +L WN ++ G + V SE LW PD+VL NA
Sbjct: 64 QLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADG 123
Query: 391 TTXGDYALRARVSNNGSXSWXKXA 462
G + V +NG+ W A
Sbjct: 124 RFEGSLMTKVIVKSNGTVVWTPPA 147
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 364 DVVLL-NAAATTXGDYALRARVSNNGSXSWXKXA 462
D+VL NA T V +NGS W A
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPA 100
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/144 (27%), Positives = 60/144 (41%), Gaps = 7/144 (4%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP----DSKIVVNLTLHLR 219
LI+ +P T S AE E+A ++ L Y + P + I V L +
Sbjct: 9 LIVLGIPSSATTGFNSIAENEDA-----LLRHLFQGYQKWVRPVLHSNDTIKVYFGLKIS 63
Query: 220 H-ANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAA 390
++ E + L+ W D +L WN ++ G + V SE LW PD+VL NA
Sbjct: 64 QLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADG 123
Query: 391 TTXGDYALRARVSNNGSXSWXKXA 462
G + V +NG+ W A
Sbjct: 124 RFEGSLMTKVIVKSNGTVVWTPPA 147
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/144 (27%), Positives = 60/144 (41%), Gaps = 7/144 (4%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP----DSKIVVNLTLHLR 219
LI+ +P T S AE E+A ++ L Y + P + I V L +
Sbjct: 9 LIVLGIPSSATTGFNSIAENEDA-----LLRHLFQGYQKWVRPVLHSNDTIKVYFGLKIS 63
Query: 220 H-ANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAA 390
++ E + L+ W D +L WN ++ G + V SE LW PD+VL NA
Sbjct: 64 QLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADG 123
Query: 391 TTXGDYALRARVSNNGSXSWXKXA 462
G + V +NG+ W A
Sbjct: 124 RFEGSLMTKVIVKSNGTVVWTPPA 147
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/144 (27%), Positives = 60/144 (41%), Gaps = 7/144 (4%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP----DSKIVVNLTLHLR 219
LI+ +P T S AE E+A ++ L Y + P + I V L +
Sbjct: 9 LIVLGIPSSATTGFNSIAENEDA-----LLRHLFQGYQKWVRPVLHSNDTIKVYFGLKIS 63
Query: 220 H-ANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAA 390
++ E + L+ W D +L WN ++ G + V SE LW PD+VL NA
Sbjct: 64 QLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADG 123
Query: 391 TTXGDYALRARVSNNGSXSWXKXA 462
G + V +NG+ W A
Sbjct: 124 RFEGSLMTKVIVKSNGTVVWTPPA 147
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/144 (27%), Positives = 60/144 (41%), Gaps = 7/144 (4%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP----DSKIVVNLTLHLR 219
LI+ +P T S AE E+A ++ L Y + P + I V L +
Sbjct: 9 LIVLGIPSSATTGFNSIAENEDA-----LLRHLFQGYQKWVRPVLHSNDTIKVYFGLKIS 63
Query: 220 H-ANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAA 390
++ E + L+ W D +L WN ++ G + V SE LW PD+VL NA
Sbjct: 64 QLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADG 123
Query: 391 TTXGDYALRARVSNNGSXSWXKXA 462
G + V +NG+ W A
Sbjct: 124 RFEGSLMTKVIVKSNGTVVWTPPA 147
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/144 (27%), Positives = 60/144 (41%), Gaps = 7/144 (4%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPP----DSKIVVNLTLHLR 219
LI+ +P T S AE E+A ++ L Y + P + I V L +
Sbjct: 9 LIVLGIPSSATTGFNSIAENEDA-----LLRHLFQGYQKWVRPVLHSNDTIKVYFGLKIS 63
Query: 220 H-ANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAA 390
++ E + L+ W D +L WN ++ G + V SE LW PD+VL NA
Sbjct: 64 QLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADG 123
Query: 391 TTXGDYALRARVSNNGSXSWXKXA 462
G + V +NG+ W A
Sbjct: 124 RFEGSLMTKVIVKSNGTVVWTPPA 147
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTX 399
++ E + L+ W D +L WN ++ G + V SE LW PD+VL NA
Sbjct: 32 DVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFE 91
Query: 400 GDYALRARVSNNGSXSWXKXA 462
G + V +NG+ W A
Sbjct: 92 GSLMTKVIVKSNGTVVWTPPA 112
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 46.0 bits (104), Expect = 2e-04
Identities = 37/151 (24%), Positives = 68/151 (45%), Gaps = 6/151 (3%)
Frame = +1
Query: 28 SVVIKCRRLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLT 207
S+ + CR +L L LL A AS AE L + ++ S P ++++
Sbjct: 6 SLPLACRARLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFE 62
Query: 208 LHLRH-ANIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN 381
+ + + E + L+ W D +L WN +G + ++ V ++++W+PD+VL N
Sbjct: 63 VSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYN 122
Query: 382 AAATTXGDYAL----RARVSNNGSXSWXKXA 462
A GD+ + +A + G +W A
Sbjct: 123 NAV---GDFQVTTKTKALLKYTGEVTWIPPA 150
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 133 VDDKTKALLKYTGEVTWIPPA 153
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 133 VDDKTKALLKYTGEVTWIPPA 153
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 46.0 bits (104), Expect = 2e-04
Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 6/94 (6%)
Frame = +1
Query: 187 KIVVNLTL-HLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWR 360
++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +++E +W
Sbjct: 53 RVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRITAESVWL 110
Query: 361 PDVVLLNAAATTXGDY----ALRARVSNNGSXSW 450
PDVVLLN G++ + VS++GS W
Sbjct: 111 PDVVLLN---NNDGNFYVALDISVVVSSDGSVRW 141
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 133 VDDKTKALLKYTGEVTWIPPA 153
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 133 VDDKTKALLKYTGEVTWIPPA 153
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 133 VDDKTKALLKYTGEVTWIPPA 153
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 133 VDDKTKALLKYTGEVTWIPPA 153
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 10 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 66
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 67 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 126
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 127 VDDKTKALLKYTGEVTWIPPA 147
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 300
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 301 WNAGEW-GCSTWLVSSERLWRPDVVLLN 381
W+ ++ G V S +WRPD+VL N
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN 119
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 45.2 bits (102), Expect = 3e-04
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLS 300
++ L+ YD + P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 301 WNAGEW-GCSTWLVSSERLWRPDVVLLN 381
W+ ++ G V S +WRPD+VL N
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN 119
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 44.8 bits (101), Expect = 4e-04
Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 273
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 274 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNG 438
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 439 SXSWXKXA 462
+W A
Sbjct: 145 MITWTPPA 152
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 44.8 bits (101), Expect = 4e-04
Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 273
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 274 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNG 438
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 439 SXSWXKXA 462
+W A
Sbjct: 145 MITWTPPA 152
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 44.8 bits (101), Expect = 4e-04
Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 273
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 274 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNG 438
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 439 SXSWXKXA 462
+W A
Sbjct: 145 MITWTPPA 152
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 44.8 bits (101), Expect = 4e-04
Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHL-----RHANIRESESTVRIQADLQ 273
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 274 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNG 438
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAV---GDFQVEGKTKALLKYNG 144
Query: 439 SXSWXKXA 462
+W A
Sbjct: 145 MITWTPPA 152
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 44.0 bits (99), Expect = 7e-04
Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 6/115 (5%)
Frame = +1
Query: 136 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 300
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 301 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSXSWXKXA 462
WN ++G V S+ +W PD+VL + A + + + NG+ +W A
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPA 164
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 44.0 bits (99), Expect = 7e-04
Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 6/115 (5%)
Frame = +1
Query: 136 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 300
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 301 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSXSWXKXA 462
WN ++G V S+ +W PD+VL + A + + + NG+ +W A
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPA 164
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 44.0 bits (99), Expect = 7e-04
Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 6/115 (5%)
Frame = +1
Query: 136 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 300
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 301 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSXSWXKXA 462
WN ++G V S+ +W PD+VL + A + + + NG+ +W A
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPA 164
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 44.0 bits (99), Expect = 7e-04
Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 6/115 (5%)
Frame = +1
Query: 136 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 300
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 301 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSXSWXKXA 462
WN ++G V S+ +W PD+VL + A + + + NG+ +W A
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPA 164
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/74 (32%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 24 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 81
Query: 346 ERLWRPDVVLLNAA 387
++W+PD++L N+A
Sbjct: 82 GQIWKPDILLYNSA 95
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 402
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A G
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNA---DG 153
Query: 403 DYAL----RARVSNNGSXSWXKXA 462
++A+ +A + + G+ W A
Sbjct: 154 EFAVTHMTKAHLFSTGTVHWVPPA 177
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/74 (32%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLNAA 387
++W+PD++L N+A
Sbjct: 105 GQIWKPDILLYNSA 118
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 15 RLLLLLLS-LLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 70
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 71 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 130
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 131 VDDKTKALLKYTGEVTWIPPA 151
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/74 (32%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLNAA 387
++W+PD++L N+A
Sbjct: 105 GQIWKPDILLYNSA 118
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/74 (32%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLNAA 387
++W+PD++L N+A
Sbjct: 105 GQIWKPDILLYNSA 118
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLS-LLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 71
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 72 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 131
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 132 VDDKTKALLKYTGEVTWIPPA 152
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Frame = +1
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXG 402
++ E + L+ W D +L WN ++G T L V SE +W PD+VL N A G
Sbjct: 97 DVDEKNQMMTTNVWLKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNA---DG 153
Query: 403 DYAL----RARVSNNGSXSWXKXA 462
++A+ +A + + G+ W A
Sbjct: 154 EFAVTHMTKAHLFSTGTVHWVPPA 177
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 15 RLLLLLLS-LLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 70
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 71 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 130
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 131 VDDKTKALLKYTGEVTWIPPA 151
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLS-LLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 71
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 72 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 131
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 132 VDDKTKALLKYTGEVTWIPPA 152
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/74 (32%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L+L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLSL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLNAA 387
++W+PD++L N+A
Sbjct: 105 GQIWKPDILLYNSA 118
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +1
Query: 49 RLILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIVVNLTLHLRH-A 225
RL+L L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLS-LLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 71
Query: 226 NIRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTX 399
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL NA
Sbjct: 72 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 131
Query: 400 GDYALRARVSNNGSXSWXKXA 462
D +A + G +W A
Sbjct: 132 VDDKTKALLKYTGEVTWIPPA 152
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 42.7 bits (96), Expect = 0.002
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLNAA 387
++W+PD++L N+A
Sbjct: 105 GQIWKPDILLYNSA 118
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 42.7 bits (96), Expect = 0.002
Identities = 28/115 (24%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Frame = +1
Query: 136 MIDSLLATYDRDSPP----DSKIVVNLTLHLRH-ANIRESESTVRIQADLQMNWIDKRLS 300
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 301 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSXSWXKXA 462
WN ++G V S+ W PD+VL + A + + + NG+ +W A
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPA 164
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Frame = +1
Query: 103 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 258
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 259 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRARVSN 432
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 433 NGSXSWXKXA 462
+G+ W A
Sbjct: 139 DGAVRWDAPA 148
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Frame = +1
Query: 103 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 258
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 259 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRARVSN 432
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 433 NGSXSWXKXA 462
+G+ W A
Sbjct: 139 DGAVRWDAPA 148
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 42.7 bits (96), Expect = 0.002
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Frame = +1
Query: 169 DSPPDSKIVVNLTLHLRHANIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSS 345
DS P + + +L L L+ ++ E + LQM+W D L WN E+ G T
Sbjct: 47 DSQPLT-VYFSLNL-LQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPD 104
Query: 346 ERLWRPDVVLLNAA 387
++W+PD++L N+A
Sbjct: 105 GQIWKPDILLYNSA 118
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Frame = +1
Query: 103 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 258
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 259 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRARVSN 432
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 433 NGSXSWXKXA 462
+G+ W A
Sbjct: 139 DGAVRWDAPA 148
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Frame = +1
Query: 103 AEC---ENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANI---RESESTVRI 258
AEC E +L L D L A Y P D+ +N+TL + + I E + +
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 259 QADLQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTXGDYALRARVSN 432
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 433 NGSXSWXKXA 462
+G+ W A
Sbjct: 139 DGAVRWDAPA 148
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLL-NAAATTXGDYALRARVSNNGS 441
L+ W D +L WN ++G + ++ V ++++W+PD+VL NA D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 442 XSWXKXA 462
+W A
Sbjct: 116 VTWIPPA 122
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 387
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 387
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 387
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 387
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 16 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 75
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 387
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 76 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 117
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = +1
Query: 100 AAECENATSLSLMIDSLLATYDRDSPP--DSKIVVNLTLHLRHANIRESESTVRIQAD-- 267
AAE + + + L Y P D+ V+N+TL + + I++ + +I
Sbjct: 22 AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYL 81
Query: 268 -LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA 387
++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 82 WIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKA 123
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 41.9 bits (94), Expect = 0.003
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 355 WRPDVVLLN 381
W P++VL N
Sbjct: 109 WLPEIVLEN 117
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 41.9 bits (94), Expect = 0.003
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 355 WRPDVVLLN 381
W P++VL N
Sbjct: 109 WLPEIVLEN 117
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 41.9 bits (94), Expect = 0.003
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 355 WRPDVVLLN 381
W P++VL N
Sbjct: 109 WLPEIVLEN 117
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 41.9 bits (94), Expect = 0.003
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Frame = +1
Query: 181 DSKIVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEWG-CSTWLVSSERL 354
+ + V L L L + +++E E T+ ++ W D RL WNA E+G S + + +
Sbjct: 49 EESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMV 108
Query: 355 WRPDVVLLN 381
W P++VL N
Sbjct: 109 WLPEIVLEN 117
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 40.7 bits (91), Expect = 0.006
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 10/119 (8%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 300
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 301 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSXSWXKXA 462
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G W A
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPA 155
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 40.7 bits (91), Expect = 0.006
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 10/119 (8%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 300
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 301 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSXSWXKXA 462
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G W A
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPA 155
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 40.7 bits (91), Expect = 0.006
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 10/119 (8%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 300
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 301 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSXSWXKXA 462
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G W A
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPA 130
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 40.7 bits (91), Expect = 0.006
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 10/119 (8%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 300
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 301 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSXSWXKXA 462
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G W A
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPA 155
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 40.7 bits (91), Expect = 0.006
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 10/119 (8%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 300
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 301 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSXSWXKXA 462
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G W A
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPA 155
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 40.7 bits (91), Expect = 0.006
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 10/119 (8%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 300
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 301 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSXSWXKXA 462
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G W A
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPA 155
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 40.7 bits (91), Expect = 0.006
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 10/119 (8%)
Frame = +1
Query: 136 MIDSLLATYDRDSPPDSKI--VVNLTLHLRHA---NIRESESTVRIQADLQMNWIDKRLS 300
++ L + Y++ S P + I VV + L A ++ E + ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 301 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTXGDYAL----RARVSNNGSXSWXKXA 462
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G W A
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNA---DGDFAVTHLTKAHLFHDGRVQWTPPA 155
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 39.1 bits (87), Expect = 0.019
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNG 438
L+++W+D RL+WN + E LW P + +L A D + +ARV +G
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDG 142
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 39.1 bits (87), Expect = 0.019
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNG 438
L+++W+D RL+WN + E LW P + +L A D + +ARV +G
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDG 143
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 39.1 bits (87), Expect = 0.019
Identities = 38/140 (27%), Positives = 56/140 (40%), Gaps = 4/140 (2%)
Frame = +1
Query: 55 ILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPDSKIV-VNLTLHLRHA-N 228
+L L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 229 IRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLL-NAAATTXG 402
+ E E + L W D RL+W E+ + S+ +W PDVVL NA
Sbjct: 70 VHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEV 129
Query: 403 DYALRARVSNNGSXSWXKXA 462
+ A VS +GS W A
Sbjct: 130 SFYSNAVVSYDGSIFWLPPA 149
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 39.1 bits (87), Expect = 0.019
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNG 438
L+++W+D RL+WN + E LW P + +L A D + +ARV +G
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDG 142
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 39.1 bits (87), Expect = 0.019
Identities = 18/57 (31%), Positives = 29/57 (50%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNG 438
L+++W+D RL+WN + E LW P + +L A D + +ARV +G
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDG 142
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 38.3 bits (85), Expect = 0.033
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLL-NAAATTXGDYALRARVSNNGSXSWXKXA 462
DVVL NA + A VS +GS W A
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPA 149
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 38.3 bits (85), Expect = 0.033
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLL-NAAATTXGDYALRARVSNNGSXSWXKXA 462
DVVL NA + A VS +GS W A
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPA 149
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 38.3 bits (85), Expect = 0.033
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLL-NAAATTXGDYALRARVSNNGSXSWXKXA 462
DVVL NA + A VS +GS W A
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPA 149
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 38.3 bits (85), Expect = 0.033
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLL-NAAATTXGDYALRARVSNNGSXSWXKXA 462
DVVL NA + A VS +GS W A
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPA 149
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 38.3 bits (85), Expect = 0.033
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLL-NAAATTXGDYALRARVSNNGSXSWXKXA 462
DVVL NA + A VS +GS W A
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPA 149
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 38.3 bits (85), Expect = 0.033
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLL-NAAATTXGDYALRARVSNNGSXSWXKXA 462
DVVL NA + A VS +GS W A
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPA 149
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 38.3 bits (85), Expect = 0.033
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Frame = +1
Query: 190 IVVNLTLHLRHA-NIRESESTVRIQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 363
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 364 DVVLL-NAAATTXGDYALRARVSNNGSXSWXKXA 462
DVVL NA + A VS +GS W A
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPA 149
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 36.7 bits (81), Expect = 0.10
Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 4/114 (3%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 222
L+ F + + C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 223 AN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN 381
+ + E + Q +W DKRLS++ + +++LW PD LN
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLN 125
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 36.3 bits (80), Expect = 0.13
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSX 444
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 445 SWXK 456
+ K
Sbjct: 151 RYKK 154
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 36.3 bits (80), Expect = 0.13
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSX 444
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 445 SWXK 456
+ K
Sbjct: 80 RYKK 83
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 36.3 bits (80), Expect = 0.13
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSX 444
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 445 SWXK 456
+ K
Sbjct: 166 RYKK 169
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 36.3 bits (80), Expect = 0.13
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSX 444
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 445 SWXK 456
+ K
Sbjct: 166 RYKK 169
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 36.3 bits (80), Expect = 0.13
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSX 444
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 445 SWXK 456
+ K
Sbjct: 166 RYKK 169
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 35.9 bits (79), Expect = 0.18
Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 4/114 (3%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 222
L+ F + + C S E N + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 223 AN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN 381
+ + E + Q +W DKRLS++ + +++LW PD LN
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLN 125
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 35.5 bits (78), Expect = 0.23
Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 7/110 (6%)
Frame = +1
Query: 73 FLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-I 231
F L A A + +++SL+ +D LL YD PD + V + + + + +
Sbjct: 15 FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74
Query: 232 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN 381
E + Q W DKRLS+N + +++LW PD LN
Sbjct: 75 SEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 35.5 bits (78), Expect = 0.23
Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 7/110 (6%)
Frame = +1
Query: 73 FLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-I 231
F L A A + +++SL+ +D LL YD PD + V + + + + +
Sbjct: 15 FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74
Query: 232 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN 381
E + Q W DKRLS+N + +++LW PD LN
Sbjct: 75 SEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 35.5 bits (78), Expect = 0.23
Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 7/110 (6%)
Frame = +1
Query: 73 FLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-I 231
F L A A + +++SL+ +D LL YD PD + V + + + + +
Sbjct: 15 FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74
Query: 232 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN 381
E + Q W DKRLS+N + +++LW PD LN
Sbjct: 75 SEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 35.5 bits (78), Expect = 0.23
Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 7/110 (6%)
Frame = +1
Query: 73 FLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-I 231
F L A A + +++SL+ +D LL YD PD + V + + + + +
Sbjct: 15 FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74
Query: 232 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN 381
E + Q W DKRLS+N + +++LW PD LN
Sbjct: 75 SEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 35.5 bits (78), Expect = 0.23
Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 7/110 (6%)
Frame = +1
Query: 73 FLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-I 231
F L A A + +++SL+ +D LL YD PD + V + + + + +
Sbjct: 15 FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74
Query: 232 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN 381
E + Q W DKRLS+N + +++LW PD LN
Sbjct: 75 SEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 35.5 bits (78), Expect = 0.23
Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 7/110 (6%)
Frame = +1
Query: 73 FLLTCAIASAAECENATSLSLM---IDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-I 231
F L A A + +++SL+ +D LL YD PD + V + + + + +
Sbjct: 15 FPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMV 74
Query: 232 RESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN 381
E + Q W DKRLS+N + +++LW PD LN
Sbjct: 75 SEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLN 124
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 35.1 bits (77), Expect = 0.31
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Frame = +1
Query: 139 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 306
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 307 AGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARV 426
++LW PD ++NA + D + ++
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKL 143
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 35.1 bits (77), Expect = 0.31
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Frame = +1
Query: 139 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 306
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 307 AGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARV 426
++LW PD ++NA + D + ++
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKL 143
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 35.1 bits (77), Expect = 0.31
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Frame = +1
Query: 139 IDSLLATYDRDSPPD-SKIVVNLTLHLRHANI---RESESTVRIQADLQMNWIDKRLSWN 306
+D L+A Y R+ P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 307 AGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARV 426
++LW PD ++NA + D + ++
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKL 143
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 34.7 bits (76), Expect = 0.40
Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Frame = +1
Query: 256 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 432
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 87 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 146
Query: 433 NGSXSWXK 456
G + K
Sbjct: 147 EGRIRYKK 154
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 34.7 bits (76), Expect = 0.40
Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Frame = +1
Query: 256 IQADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSN 432
+ A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN
Sbjct: 72 MSAILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSN 131
Query: 433 NGSXSWXK 456
G + K
Sbjct: 132 EGRIRYKK 139
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 33.9 bits (74), Expect = 0.71
Identities = 25/110 (22%), Positives = 44/110 (40%), Gaps = 4/110 (3%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 276
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 277 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARV 426
W D RL++ + E+LW PD LN+ D + RV
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRV 162
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 33.9 bits (74), Expect = 0.71
Identities = 25/110 (22%), Positives = 44/110 (40%), Gaps = 4/110 (3%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 276
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 277 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARV 426
W D RL++ + E+LW PD LN+ D + RV
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRV 162
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 33.9 bits (74), Expect = 0.71
Identities = 25/110 (22%), Positives = 44/110 (40%), Gaps = 4/110 (3%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 276
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 277 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARV 426
W D RL++ + E+LW PD LN+ D + RV
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRV 162
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 33.9 bits (74), Expect = 0.71
Identities = 25/110 (22%), Positives = 44/110 (40%), Gaps = 4/110 (3%)
Frame = +1
Query: 109 CENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRHAN-IRESESTVRIQADLQM 276
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 277 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARV 426
W D RL++ + E+LW PD LN+ D + RV
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRV 157
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 32.3 bits (70), Expect = 2.2
Identities = 16/64 (25%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSX 444
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 445 SWXK 456
+ K
Sbjct: 151 KYDK 154
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 32.3 bits (70), Expect = 2.2
Identities = 16/64 (25%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +1
Query: 268 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNNGSX 444
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 445 SWXK 456
+ K
Sbjct: 151 KYDK 154
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 31.5 bits (68), Expect = 3.8
Identities = 27/114 (23%), Positives = 47/114 (41%), Gaps = 4/114 (3%)
Frame = +1
Query: 52 LILFWLPFLLTCAIASAAECENATSLSLMIDSLLATYDRDSPPD---SKIVVNLTLHLRH 222
L+ F + + C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 223 AN-IRESESTVRIQADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLN 381
+ + E + Q +W DKRLS++ + +++L PD LN
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLN 125
>U83981-1|AAC25631.1| 674|Homo sapiens apoptosis associated protein
protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 427 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 293
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>CR457259-1|CAG33540.1| 674|Homo sapiens PPP1R15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 427 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 293
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC003067-1|AAH03067.1| 674|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 15A protein.
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 427 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 293
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>AK001361-1|BAA91649.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ10499 fis, clone NT2RP2000346, weakly similar to
MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD116.
).
Length = 674
Score = 31.1 bits (67), Expect = 5.0
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Frame = -3
Query: 427 IHGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSP-TPLRSNSV 293
I+ GE+ P W PRL + Q P TP P TPL++ V
Sbjct: 511 IYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKV 556
>BC146774-1|AAI46775.1| 1114|Homo sapiens GPR124 protein protein.
Length = 1114
Score = 30.3 bits (65), Expect = 8.7
Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Frame = +1
Query: 301 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNN-GSXSWXK 456
W +GEW C+ + + ++V+L +A+ Y RV+NN G W +
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLETSAS----YCPAERVANNRGDFRWPR 362
>AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled receptor
124 protein.
Length = 1331
Score = 30.3 bits (65), Expect = 8.7
Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Frame = +1
Query: 301 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNN-GSXSWXK 456
W +GEW C+ + + ++V+L +A+ Y RV+NN G W +
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLETSAS----YCPAERVANNRGDFRWPR 362
>AK122582-1|BAC56923.1| 1383|Homo sapiens FLJ00269 protein protein.
Length = 1383
Score = 30.3 bits (65), Expect = 8.7
Identities = 13/38 (34%), Positives = 18/38 (47%)
Frame = -3
Query: 424 HGRGERSPRRWLQPRLAVPRQASTSVPRTPAKCCSPTP 311
HG + SP W Q + + P + P P +CCS P
Sbjct: 256 HGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGP 293
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 30.3 bits (65), Expect = 8.7
Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Frame = +1
Query: 301 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNN-GSXSWXK 456
W +GEW C+ + + ++V+L +A+ Y RV+NN G W +
Sbjct: 293 WASGEWECTVSMAQGNASKKVEIVVLETSAS----YCPAERVANNRGDFRWPR 341
>AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marker 5
precursor protein.
Length = 1331
Score = 30.3 bits (65), Expect = 8.7
Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Frame = +1
Query: 301 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNN-GSXSWXK 456
W +GEW C+ + + ++V+L +A+ Y RV+NN G W +
Sbjct: 314 WASGEWECTVSMAQGNASKKVEIVVLETSAS----YCPAERVANNRGDFRWPR 362
>AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein.
Length = 1206
Score = 30.3 bits (65), Expect = 8.7
Identities = 15/53 (28%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Frame = +1
Query: 301 WNAGEWGCSTWLVSSERLWRPDVVLLNAAATTXGDYALRARVSNN-GSXSWXK 456
W +GEW C+ + + ++V+L +A+ Y RV+NN G W +
Sbjct: 406 WASGEWECTVSMAQGNASKKVEIVVLETSAS----YCPAERVANNRGDFRWPR 454
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,136,379
Number of Sequences: 237096
Number of extensions: 1977616
Number of successful extensions: 5565
Number of sequences better than 10.0: 128
Number of HSP's better than 10.0 without gapping: 4995
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5459
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10147868276
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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