Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BmNP12_FL5_I06
(841 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 65 3e-10
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 63 1e-09
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 63 1e-09
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 63 1e-09
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 63 1e-09
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 63 1e-09
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 61 6e-09
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 61 6e-09
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 61 6e-09
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 61 6e-09
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 61 6e-09
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 61 6e-09
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 61 6e-09
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 60 7e-09
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 60 7e-09
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 60 7e-09
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 60 7e-09
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 60 1e-08
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 60 1e-08
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 60 1e-08
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 60 1e-08
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 60 1e-08
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 60 1e-08
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 60 1e-08
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 60 1e-08
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 59 2e-08
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 59 2e-08
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 58 3e-08
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 58 3e-08
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 58 3e-08
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 58 3e-08
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 58 3e-08
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 58 3e-08
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 58 4e-08
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 58 4e-08
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 57 9e-08
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 57 9e-08
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 57 9e-08
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 57 9e-08
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 56 1e-07
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 56 1e-07
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 55 3e-07
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 55 3e-07
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 55 3e-07
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 55 3e-07
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 55 3e-07
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 55 3e-07
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 55 3e-07
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 55 3e-07
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 54 5e-07
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 54 5e-07
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 54 5e-07
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 54 5e-07
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 54 5e-07
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 54 5e-07
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 53 1e-06
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 53 1e-06
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 53 1e-06
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 53 1e-06
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 53 1e-06
DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit ... 52 3e-06
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 52 3e-06
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 52 3e-06
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 52 3e-06
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 52 3e-06
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 52 3e-06
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 51 5e-06
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 51 5e-06
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 51 6e-06
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 51 6e-06
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 50 8e-06
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 50 8e-06
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 50 8e-06
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 50 8e-06
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 50 8e-06
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 50 8e-06
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 50 8e-06
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 50 8e-06
BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channe... 50 8e-06
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 50 8e-06
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 50 8e-06
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 50 8e-06
AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa) (... 50 8e-06
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 50 8e-06
AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channe... 50 8e-06
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 50 8e-06
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 50 1e-05
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 50 1e-05
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 50 1e-05
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 50 1e-05
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 50 1e-05
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 50 1e-05
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 50 1e-05
AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channe... 50 1e-05
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 49 2e-05
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 49 2e-05
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 49 2e-05
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 49 2e-05
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 49 2e-05
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 49 2e-05
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 49 2e-05
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 49 2e-05
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 49 2e-05
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 48 6e-05
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 48 6e-05
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 47 7e-05
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 47 7e-05
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 47 1e-04
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 47 1e-04
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 47 1e-04
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 47 1e-04
BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein. 47 1e-04
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 47 1e-04
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 47 1e-04
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 47 1e-04
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 46 1e-04
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 45 3e-04
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 45 3e-04
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 45 3e-04
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 45 3e-04
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 45 4e-04
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 45 4e-04
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 45 4e-04
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 44 5e-04
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 44 5e-04
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 44 5e-04
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 44 5e-04
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 44 5e-04
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 43 0.001
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 43 0.001
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 43 0.001
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 42 0.002
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 42 0.002
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 42 0.002
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 42 0.002
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 42 0.004
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 42 0.004
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 42 0.004
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 42 0.004
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 42 0.004
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 42 0.004
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 40 0.015
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 39 0.020
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 39 0.020
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 38 0.034
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 38 0.034
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 38 0.034
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 37 0.079
AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor, n... 30 9.1
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 64.9 bits (151), Expect = 3e-10
Identities = 45/171 (26%), Positives = 76/171 (44%), Gaps = 8/171 (4%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRAR 427
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNDGTYEVSVYTNLI 133
Query: 428 VSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V +NGSV + + +++ +P D Q CT KF S + D V+
Sbjct: 134 VRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 184
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 62.9 bits (146), Expect = 1e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V +NGSV + + +++ +P D Q CT KF S + D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 62.9 bits (146), Expect = 1e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V +NGSV + + +++ +P D Q CT KF S + D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 62.9 bits (146), Expect = 1e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V +NGSV + + +++ +P D Q CT KF S + D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 62.9 bits (146), Expect = 1e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V +NGSV + + +++ +P D Q CT KF S + D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 62.9 bits (146), Expect = 1e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V +NGSV + + +++ +P D Q CT KF S + D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 62.9 bits (146), Expect = 1e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 9/172 (5%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRA 424
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N A T
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNL 133
Query: 425 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V +NGSV + + +++ +P D Q CT KF S + D V+
Sbjct: 134 IVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVL 185
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 60.9 bits (141), Expect = 6e-09
Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V + +M + +P D Q C+ KFGS D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 60.9 bits (141), Expect = 6e-09
Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 46 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 105
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V + +M + +P D Q C+ KFGS D ++
Sbjct: 106 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 150
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 60.9 bits (141), Expect = 6e-09
Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V + +M + +P D Q C+ KFGS D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 60.9 bits (141), Expect = 6e-09
Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V + +M + +P D Q C+ KFGS D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 60.9 bits (141), Expect = 6e-09
Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V + +M + +P D Q C+ KFGS D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 60.9 bits (141), Expect = 6e-09
Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V + +M + +P D Q C+ KFGS D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 60.9 bits (141), Expect = 6e-09
Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLL-NAAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + V SE LW PD+VL NA G + V +NG+
Sbjct: 81 LKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGT 140
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V + +M + +P D Q C+ KFGS D ++
Sbjct: 141 VVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLIL 185
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 60.5 bits (140), Expect = 7e-09
Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
++ + +P D+Q C+ KFGS Q D ++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIIL 202
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 60.5 bits (140), Expect = 7e-09
Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
++ + +P D+Q C+ KFGS Q D ++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIIL 202
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 60.5 bits (140), Expect = 7e-09
Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
++ + +P D+Q C+ KFGS Q D ++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIIL 202
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 60.5 bits (140), Expect = 7e-09
Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 6/153 (3%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 481
WN ++G V S+ +W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
++ + +P D+Q C+ KFGS Q D ++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIIL 202
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 60.1 bits (139), Expect = 1e-08
Identities = 47/189 (24%), Positives = 84/189 (44%), Gaps = 6/189 (3%)
Frame = +2
Query: 32 SVVIKCRRLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLT 211
S+ + CR +L LL A AS AE L + ++ S P ++++
Sbjct: 6 SLPLACRARLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFE 62
Query: 212 LHLRH-ANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN 385
+ + + E + L+ W D +L WN +G + ++ V ++++W+PD+VL N
Sbjct: 63 VSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSGYGGAEFMRVPAQKIWKPDIVLYN 122
Query: 386 AAATTAGDYAL----RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMX 553
A GD+ + +A + G V+ I + + + +P D Q CT KFGS
Sbjct: 123 NAV---GDFQVTTKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSY 179
Query: 554 HXDQTDXVI 580
+ D V+
Sbjct: 180 DKAKIDLVL 188
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 60.1 bits (139), Expect = 1e-08
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 3/179 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
D +A + G V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 60.1 bits (139), Expect = 1e-08
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 3/179 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
D +A + G V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 60.1 bits (139), Expect = 1e-08
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 3/179 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
D +A + G V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 60.1 bits (139), Expect = 1e-08
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 3/179 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
D +A + G V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 60.1 bits (139), Expect = 1e-08
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 3/179 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
D +A + G V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 60.1 bits (139), Expect = 1e-08
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 3/179 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 16 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 72
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 73 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 132
Query: 404 GDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
D +A + G V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 133 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 191
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 60.1 bits (139), Expect = 1e-08
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 3/179 (1%)
Frame = +2
Query: 53 RLILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHLRH-A 229
RL+L LL A AS AE L + ++ S P ++++ + +
Sbjct: 10 RLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDP---VIIHFEVSMSQLV 66
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTA 403
+ E + L+ W D +L WN ++G + ++ V ++++W+PD+VL N A
Sbjct: 67 KVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQ 126
Query: 404 GDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
D +A + G V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 127 VDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 185
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 59.3 bits (137), Expect = 2e-08
Identities = 37/153 (24%), Positives = 68/153 (44%), Gaps = 6/153 (3%)
Frame = +2
Query: 140 MIDSLLATYDRESPP----DSKIVVNLTLHLRH-ANIRESESTVRILADLQMNWIDKRLS 304
++ L Y+R P + KI + L + ++ E + L+ WID +L
Sbjct: 50 LLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLR 109
Query: 305 WNAGEWG-CSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTP 481
WN ++G V S+ W PD+VL + A + + + NG+V+ + +
Sbjct: 110 WNPDDYGGIKVIRVPSDSSWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSS 169
Query: 482 ISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
++ + +P D+Q C+ KFGS Q D ++
Sbjct: 170 CTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIIL 202
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 58.8 bits (136), Expect = 2e-08
Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
I + L L L ++ E + + L+ W D RL+WN+ + G + + ++R+W P
Sbjct: 7 ISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLP 66
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
D+VL N A T V +NGSV + + +++ +P D Q CT KF S
Sbjct: 67 DIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRS 126
Query: 545 RMXHXDQTDXVI 580
+ D V+
Sbjct: 127 WTYDHTEIDMVL 138
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 56 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 115
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 116 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 160
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 85 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 144
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 145 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 189
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLN-AAATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G + ++ V ++++W+PD+VL N A D +A + G
Sbjct: 86 LKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGE 145
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
V+ I + + + +P D Q CT KFGS + D V+
Sbjct: 146 VTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVL 190
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 58.0 bits (134), Expect = 4e-08
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
V + + S+ + +P D Q C KFGS
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 58.0 bits (134), Expect = 4e-08
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
L+ W D +L WN ++G T L V SE +W PD+VL N A A + +A + + G+
Sbjct: 111 LKQEWSDYKLRWNPADFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGT 170
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
V + + S+ + +P D Q C KFGS
Sbjct: 171 VHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGS 203
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 56.8 bits (131), Expect = 9e-08
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
++ + M + +P D Q C+ KFGS + D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 56.8 bits (131), Expect = 9e-08
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
++ + M + +P D Q C+ KFGS + D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 56.8 bits (131), Expect = 9e-08
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
++ + M + +P D Q C+ KFGS + D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 56.8 bits (131), Expect = 9e-08
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPDSKIVVNLTLHL-----RHANIRESESTVRILADLQ 277
C + + L + Y++ P + +T+H + AN+ E + L+
Sbjct: 28 CVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLR 87
Query: 278 MNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNG 442
W D +L W+ E+ G T V ++++W+PD+VL N A GD+ + +A + NG
Sbjct: 88 HIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNA---VGDFQVEGKTKALLKYNG 144
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
++ + M + +P D Q C+ KFGS + D +I
Sbjct: 145 MITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI 190
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 56.4 bits (130), Expect = 1e-07
Identities = 44/129 (34%), Positives = 64/129 (49%), Gaps = 4/129 (3%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSXIKRLDISTPISMQLDXWPNDM 517
++E +W PDVVLLN D AL VS++GSV + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 518 QTCTFKFGS 544
Q CT F S
Sbjct: 163 QNCTMVFSS 171
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 56.4 bits (130), Expect = 1e-07
Identities = 44/129 (34%), Positives = 64/129 (49%), Gaps = 4/129 (3%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSXIKRLDISTPISMQLDXWPNDM 517
++E +W PDVVLLN D AL VS++GSV + S+Q+ +P D
Sbjct: 104 TAESVWLPDVVLLNNNDGNF-DVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPFDW 162
Query: 518 QTCTFKFGS 544
Q CT F S
Sbjct: 163 QNCTMVFSS 171
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDXWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDXWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 15 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 74
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 75 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 131
Query: 470 ISTPISMQLDXWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 132 YKSSCSIDVTFFPFDQQNCTMKFGS 156
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDXWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDXWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDXWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 55.2 bits (127), Expect = 3e-07
Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 10/145 (6%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANIRESESTVRILAD---LQMNWIDKRLS 304
++ L + Y++ S P + I VV + L A + + + +++ ++ W D +L
Sbjct: 40 LLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLR 99
Query: 305 WNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL----RARVSNNGSVSXIKRLD 469
W+ ++ T + + SE +WRPD+VL N A GD+A+ +A + ++G V
Sbjct: 100 WDPADYENVTSIRIPSELIWRPDIVLYNNAD---GDFAVTHLTKAHLFHDGRVQWTPPAI 156
Query: 470 ISTPISMQLDXWPNDMQTCTFKFGS 544
+ S+ + +P D Q CT KFGS
Sbjct: 157 YKSSCSIDVTFFPFDQQNCTMKFGS 181
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 55.2 bits (127), Expect = 3e-07
Identities = 42/131 (32%), Positives = 65/131 (49%), Gaps = 6/131 (4%)
Frame = +2
Query: 170 RESPPDSKIVVNLTL-HLRHANIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLV 343
RE ++ V L L L N ++ E + ++ DL+ W D RLSW+ E G + +
Sbjct: 46 REVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLE--WTDYRLSWDPAEHDGIDSLRI 103
Query: 344 SSERLWRPDVVLLNAAATTAGDY----ALRARVSNNGSVSXIKRLDISTPISMQLDXWPN 511
++E +W PDVVLLN G++ + VS++GSV + S+Q+ +P
Sbjct: 104 TAESVWLPDVVLLN---NNDGNFYVALDISVVVSSDGSVRWQPPGIYRSSCSIQVTYFPF 160
Query: 512 DMQTCTFKFGS 544
D Q CT F S
Sbjct: 161 DWQNCTMVFSS 171
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 7/178 (3%)
Frame = +2
Query: 59 ILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHAN 232
I FC+ + + AAE + + + L Y P D+ V+N+TL + +
Sbjct: 8 ISFCWIYFAASRLR-AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQ 66
Query: 233 IRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT 400
I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 67 IKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDE 126
Query: 401 AGD-YALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+ + + +G ++ + + + +P D Q C FGS + +Q D
Sbjct: 127 SSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 7/178 (3%)
Frame = +2
Query: 59 ILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHAN 232
I FC+ + + AAE + + + L Y P D+ V+N+TL + +
Sbjct: 8 ISFCWIYFAASRLR-AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQ 66
Query: 233 IRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT 400
I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 67 IKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDE 126
Query: 401 AGD-YALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+ + + +G ++ + + + +P D Q C FGS + +Q D
Sbjct: 127 SSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 7/178 (3%)
Frame = +2
Query: 59 ILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHAN 232
I FC+ + + AAE + + + L Y P D+ V+N+TL + +
Sbjct: 8 ISFCWIYFAASRLR-AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQ 66
Query: 233 IRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT 400
I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 67 IKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDE 126
Query: 401 AGD-YALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+ + + +G ++ + + + +P D Q C FGS + +Q D
Sbjct: 127 SSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 7/178 (3%)
Frame = +2
Query: 59 ILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHAN 232
I FC+ + + AAE + + + L Y P D+ V+N+TL + +
Sbjct: 8 ISFCWIYFAASRLR-AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQ 66
Query: 233 IRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT 400
I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 67 IKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDE 126
Query: 401 AGD-YALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+ + + +G ++ + + + +P D Q C FGS + +Q D
Sbjct: 127 SSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 7/178 (3%)
Frame = +2
Query: 59 ILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHAN 232
I FC+ + + AAE + + + L Y P D+ V+N+TL + +
Sbjct: 2 ISFCWIYFAASRLR-AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQ 60
Query: 233 IRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT 400
I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 61 IKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDE 120
Query: 401 AGD-YALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+ + + +G ++ + + + +P D Q C FGS + +Q D
Sbjct: 121 SSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 178
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 54.4 bits (125), Expect = 5e-07
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 7/178 (3%)
Frame = +2
Query: 59 ILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHAN 232
I FC+ + + AAE + + + L Y P D+ V+N+TL + +
Sbjct: 8 ISFCWIYFAASRLR-AAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQ 66
Query: 233 IRESESTVRILAD---LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATT 400
I++ + +IL ++ W D L+W+ ++ G + + S+ +WRPD+VL N A
Sbjct: 67 IKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDE 126
Query: 401 AGD-YALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+ + + +G ++ + + + +P D Q C FGS + +Q D
Sbjct: 127 SSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVD 184
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIRES 244
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL- 418
V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 419 ---RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + G ++ + + + +P D Q C+ K G+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIRES 244
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL- 418
V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 419 ---RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + G ++ + + + +P D Q C+ K G+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIRES 244
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL- 418
V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 419 ---RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + G ++ + + + +P D Q C+ K G+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIRES 244
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL- 418
V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 419 ---RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + G ++ + + + +P D Q C+ K G+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHA---NIRES 244
LL ++ SA + + ++ L Y P D + VV +T+ L+ N+ E
Sbjct: 7 LLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEV 66
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEWGCSTWL-VSSERLWRPDVVLLNAAATTAGDYAL- 418
V L+ W+D L WN ++G + + SE++WRPD+VL N A GD+A+
Sbjct: 67 NQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNA---DGDFAIV 123
Query: 419 ---RARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + G ++ + + + +P D Q C+ K G+
Sbjct: 124 KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGT 168
>DQ644022-1|ABG35128.1| 456|Homo sapiens 5-HT3 receptor subunit E
splice variant HTR3Ea protein.
Length = 456
Score = 52.0 bits (119), Expect = 3e-06
Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 91 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 150
Query: 449 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXD 562
K + + + ++ + +P D Q CT F S + D
Sbjct: 151 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 188
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 52.0 bits (119), Expect = 3e-06
Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 20 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 79
Query: 449 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXD 562
K + + + ++ + +P D Q CT F S + D
Sbjct: 80 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 117
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 52.0 bits (119), Expect = 3e-06
Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXD 562
K + + + ++ + +P D Q CT F S + D
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 203
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 52.0 bits (119), Expect = 3e-06
Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXD 562
K + + + ++ + +P D Q CT F S + D
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 203
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 52.0 bits (119), Expect = 3e-06
Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
L+M W + +SWN E G + ++++ LW PD+ ++ L A VSN G +
Sbjct: 106 LEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRI 165
Query: 449 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXD 562
K + + + ++ + +P D Q CT F S + D
Sbjct: 166 RYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 203
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 52.0 bits (119), Expect = 3e-06
Identities = 46/178 (25%), Positives = 74/178 (41%), Gaps = 4/178 (2%)
Frame = +2
Query: 59 ILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKIV-VNLTLHLRHA-N 232
+L + L C+ A+ E L+ S R + S++V V L + L +
Sbjct: 10 LLLGFGLLRLCSGVWGADTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLIS 69
Query: 233 IRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAG 406
+ E E + L W D RL+W E+ + S+ +W PDVVL N A
Sbjct: 70 VHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEV 129
Query: 407 DYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTDXVI 580
+ A VS +GS+ + + +++ +P D Q CT KF S + D V+
Sbjct: 130 SFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVL 187
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 8/152 (5%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 304
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSXIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL VS +G + +
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+ S+ + +P D Q C+ F S+ ++ D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 51.2 bits (117), Expect = 5e-06
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 8/152 (5%)
Frame = +2
Query: 140 MIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLS 304
++ L+ YD P + VVN++L L N+ E E + ++M W D RL
Sbjct: 32 LLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLR 91
Query: 305 WNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYAL--RARVSNNGSVSXIKRLDIS 475
W+ ++ G V S +WRPD+VL N + AL VS +G + +
Sbjct: 92 WDPRDYEGLWVLRVPSTMVWRPDIVLEN-NVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 150
Query: 476 TPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+ S+ + +P D Q C+ F S+ ++ D
Sbjct: 151 SACSISVTYFPFDWQNCSLIFQSQTYSTNEID 182
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 50.8 bits (116), Expect = 6e-06
Identities = 32/133 (24%), Positives = 66/133 (49%), Gaps = 3/133 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTF 532
+W P++VL N G Y V GSV+ + + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 KFGSRMXHXDQTD 571
F S+ + ++ +
Sbjct: 165 IFRSQTYNAEEVE 177
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 50.8 bits (116), Expect = 6e-06
Identities = 32/133 (24%), Positives = 66/133 (49%), Gaps = 3/133 (2%)
Frame = +2
Query: 182 PDSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG-CSTWLVSSER 355
P+ + ++L + L + ++ E E T+ + ++W D RL+++ ++G T V SE
Sbjct: 45 PEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSEL 104
Query: 356 LWRPDVVLLNAAATTAG-DYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTF 532
+W P++VL N G Y V GSV+ + + ++++ +P D Q C+
Sbjct: 105 VWLPEIVLENNIDGQFGVAYDANVLVYEGGSVTWLPPAIYRSVCAVEVTYFPFDWQNCSL 164
Query: 533 KFGSRMXHXDQTD 571
F S+ + ++ +
Sbjct: 165 IFRSQTYNAEEVE 177
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 50.4 bits (115), Expect = 8e-06
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 55 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 114
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + + + +P D+Q C KFGS
Sbjct: 115 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 147
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 3/132 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMXHXDQTDXVI 580
+ D V+
Sbjct: 176 WTYDRTEIDLVL 187
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 3/132 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMXHXDQTDXVI 580
+ D V+
Sbjct: 176 WTYDRTEIDLVL 187
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 3/132 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMXHXDQTDXVI 580
+ D V+
Sbjct: 176 WTYDRTEIDLVL 187
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 50.4 bits (115), Expect = 8e-06
Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXD 562
K + +++ ++ + +P D Q CTF F S + D
Sbjct: 151 KYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVD 188
>BC110597-1|AAI10598.1| 411|Homo sapiens ligand-gated ion channel,
zinc activated 1 protein.
Length = 411
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 XIKRLDISTPISMQLDXWPNDMQTCTFKF 538
L T + +L +P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 3/132 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMXHXDQTDXVI 580
+ D V+
Sbjct: 176 WTYDRTEIDLVL 187
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 3/132 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMXHXDQTDXVI 580
+ D V+
Sbjct: 176 WTYDRTEIDLVL 187
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 3/132 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMXHXDQTDXVI 580
+ D V+
Sbjct: 176 WTYDRTEIDLVL 187
>AK122638-1|BAC85499.1| 266|Homo sapiens yte protein of 76kDa)
(LCP2). protein.
Length = 266
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 87 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 146
Query: 452 XIKRLDISTPISMQLDXWPNDMQTCTFKF 538
L T + +L +P D C+ F
Sbjct: 147 LNLALTTETNCNFELLHFPRDHSNCSLSF 175
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+++G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGH 137
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>AF512521-1|AAO20969.1| 411|Homo sapiens ligand-gated ion channel
subunit protein.
Length = 411
Score = 50.4 bits (115), Expect = 8e-06
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 XIKRLDISTPISMQLDXWPNDMQTCTFKF 538
L T + +L +P D C+ F
Sbjct: 146 LNLALTTETNCNFELLHFPRDHSNCSLSF 174
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 50.4 bits (115), Expect = 8e-06
Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 3/132 (2%)
Frame = +2
Query: 194 IVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRP 367
+ V L + L ++ E E + L W D RL+W E+ + S+ +W P
Sbjct: 56 VTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLP 115
Query: 368 DVVLLNAA-ATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
DVVL N A + A VS +GS+ + + +++ +P D Q CT KF S
Sbjct: 116 DVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRS 175
Query: 545 RMXHXDQTDXVI 580
+ D V+
Sbjct: 176 WTYDRTEIDLVL 187
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDX 502
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCTFKFGS 544
+P D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDX 502
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCTFKFGS 544
+P D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDX 502
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCTFKFGS 544
+P D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Frame = +2
Query: 266 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 442
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 89 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 148
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXD 562
+ K + + + ++ + +P D Q CT F S + D
Sbjct: 149 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 188
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Frame = +2
Query: 266 ADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNG 442
A L + W + +SWN E G + ++++ LW PD+ ++ L A VSN G
Sbjct: 74 AILDVVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEG 133
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXD 562
+ K + + + ++ + +P D Q CT F S + D
Sbjct: 134 RIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVD 173
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 50.0 bits (114), Expect = 1e-05
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSV 448
+ + W + ++WN E G + V +E LW PD+ ++ + L A +S+ G +
Sbjct: 91 MDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRI 150
Query: 449 SXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXD 562
K + +++ + + +P D Q CTF F S + D
Sbjct: 151 KYDKPMRVTSICKLDIFYFPFDQQNCTFTFSSFLYTVD 188
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +2
Query: 164 YDRESPP----DSKIVVNLTLHLRHA-NIRESESTVRILADLQMNWIDKRLSWNAGEWG- 325
Y++E P + + V L L L + +++E E T+ ++ W D RL WNA E+G
Sbjct: 38 YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97
Query: 326 CSTWLVSSERLWRPDVVL-LNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDX 502
S + + +W P++VL N + Y+ V + G V + + + +
Sbjct: 98 ISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTY 157
Query: 503 WPNDMQTCTFKFGS 544
+P D Q C+ KF S
Sbjct: 158 FPFDWQNCSLKFSS 171
>AB223030-1|BAE19924.1| 411|Homo sapiens ligand-gated ion-channel
receptor L2 protein.
Length = 411
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/89 (29%), Positives = 41/89 (46%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSNNGSVS 451
L+++W+D RL+WN + E LW P + +L A D + +ARV +G V
Sbjct: 86 LRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVK 145
Query: 452 XIKRLDISTPISMQLDXWPNDMQTCTFKF 538
L T + +L +P D C+ F
Sbjct: 146 LNLALATETNCNFELLHFPRDHSNCSLSF 174
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+G+V + + + +P D Q C FGS Q D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+G+V + + + +P D Q C FGS Q D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +2
Query: 272 LQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSNNGS 445
LQM+W D L WN E+ G T ++W+PD++L N+A + V+ +G
Sbjct: 78 LQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNPSGH 137
Query: 446 VSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ + + + +P D+Q C KFGS
Sbjct: 138 CQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGS 170
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+G+V + + + +P D Q C FGS Q D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 10/165 (6%)
Frame = +2
Query: 107 AEC---ENATSLSLMIDSLLATYDRESPP--DSKIVVNLTLHLRHANIRESESTVRILAD 271
AEC E +L L D L A Y P D+ +N+TL + + I + + ++L
Sbjct: 20 AECLGAEGRLALKLFRD-LFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTL 78
Query: 272 ---LQMNWIDKRLSWNAGEWG-CSTWLVSSERLWRPDVVLLNAA-ATTAGDYALRARVSN 436
++ W D L W+ +G + S +WRPD+VL N A A G + + +
Sbjct: 79 YLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRH 138
Query: 437 NGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGSRMXHXDQTD 571
+G+V + + + +P D Q C FGS Q D
Sbjct: 139 DGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLD 183
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 454
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
RL IS MQL+ +P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 454
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
RL IS MQL+ +P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 454
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
RL IS MQL+ +P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/150 (24%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPPD--SKIV-VNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P +I V +++ + ++E I + +
Sbjct: 44 DNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQS 103
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 454
W D+RL + + + ++W PD N + A + R+ ++G++
Sbjct: 104 WKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLY 163
Query: 455 IKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
RL IS MQL+ +P D C KFGS
Sbjct: 164 TMRLTISAECPMQLEDFPMDAHACPLKFGS 193
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 47.6 bits (108), Expect = 6e-05
Identities = 40/170 (23%), Positives = 69/170 (40%), Gaps = 7/170 (4%)
Frame = +2
Query: 56 LILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 226
L+ F + C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 227 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 403
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 404 GDYALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
++ R+ +G+V R+ + M L +P D Q CT + S
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 181
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 454
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPY 181
Query: 455 IKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
RL I M L+ +P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 47.2 bits (107), Expect = 7e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 454
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 455 IKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
RL I M L+ +P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 47.2 bits (107), Expect = 7e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 7/150 (4%)
Frame = +2
Query: 116 ENATSLSLMIDSLLATYDRESPP---DSKIVVNLTLHLRHAN-IRESESTVRILADLQMN 283
+N T + ++D LL YD P D+ V +++ + +++ I +
Sbjct: 62 DNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQT 121
Query: 284 WIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSX 454
W D+RL ++ + + ++W PD N + A + R+ +NG++
Sbjct: 122 WHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLY 181
Query: 455 IKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
RL I M L+ +P D+ C KFGS
Sbjct: 182 TMRLTIHAECPMHLEDFPMDVHACPLKFGS 211
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 7/170 (4%)
Frame = +2
Query: 56 LILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 226
L+ F + C S E N + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMPYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 227 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 403
+ + E + Q +W DKRLS++ + +++LW PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131
Query: 404 GDYALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
++ R+ +G+V R+ + M L +P D Q CT + S
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 181
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 10/168 (5%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
++ R+ +G+V R+ + M L +P D Q CT + S
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 10/168 (5%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
++ R+ +G+V R+ + M L +P D Q CT + S
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 10/168 (5%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
++ R+ +G+V R+ + M L +P D Q CT + S
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>BC111802-1|AAI11803.1| 465|Homo sapiens CHRNG protein protein.
Length = 465
Score = 46.8 bits (106), Expect = 1e-04
Identities = 36/112 (32%), Positives = 53/112 (47%), Gaps = 6/112 (5%)
Frame = +2
Query: 80 LLTCAIASAAECENATSLSLMIDSLLATYDRESPPDSKI--VVNLTLHLRHANI---RES 244
LL A+ A+ N L+ D L+ YD P + VVN++L L N+ E
Sbjct: 11 LLLLAVCLGAQGRNQEE-RLLAD-LMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNER 68
Query: 245 ESTVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAAT 397
E + ++M W D RL W+ ++ G V S +WRPD+VL N + T
Sbjct: 69 EEALTTNVWIEMQWCDYRLRWDPRDYEGLWVLRVPSTMVWRPDIVLENKSQT 120
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 10/168 (5%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
++ R+ +G+V R+ + M L +P D Q CT + S
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 10/168 (5%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
++ R+ +G+V R+ + M L +P D Q CT + S
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 10/168 (5%)
Frame = +2
Query: 71 YRFLLTCAIASAAECENATSLSLM---IDSLLATYDRESPPD---SKIVVNLTLHLRHAN 232
+ F L A A + +++SL+ +D LL YD PD + V + + + +
Sbjct: 13 WSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASID 72
Query: 233 -IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGD 409
+ E + Q W DKRLS+N + +++LW PD LN +
Sbjct: 73 MVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHG 132
Query: 410 YALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
++ R+ +G+V R+ + M L +P D Q CT + S
Sbjct: 133 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 180
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 8/115 (6%)
Frame = +2
Query: 92 AIASAAECENATSLSLMIDSLL--ATYDRESPP--DSKIVVNLTLHLRHA---NIRESES 250
A+ C A + ++D LL Y+ P S ++++ L L A ++ E E
Sbjct: 14 ALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQ 73
Query: 251 TVRILADLQMNWIDKRLSWNAGEW-GCSTWLVSSERLWRPDVVLLNAAATTAGDY 412
+ L+ W D RL+WN+ + G + + ++R+W PD+VL N + T +
Sbjct: 74 IMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNKSLRTGSTW 128
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 XIKRLDISTPISMQLDXWPNDMQTC 526
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 XIKRLDISTPISMQLDXWPNDMQTC 526
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 53 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 112
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 113 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 172
Query: 452 XIKRLDISTPISMQLDXWPNDMQTC 526
RL + S+ L +P D Q C
Sbjct: 173 YGIRLTTTAACSLDLHKFPMDKQAC 197
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Frame = +2
Query: 113 CENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQM 280
C N + ++D +L+ YD P+ + + V +++++ I E I
Sbjct: 48 CANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQ 107
Query: 281 NWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRARVSN---NGSVS 451
W D RL++ + E+LW PD LN+ D + RV +G+V
Sbjct: 108 TWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVR 167
Query: 452 XIKRLDISTPISMQLDXWPNDMQTC 526
RL + S+ L +P D Q C
Sbjct: 168 YGIRLTTTAACSLDLHKFPMDKQAC 192
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 44.8 bits (101), Expect = 4e-04
Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 44.8 bits (101), Expect = 4e-04
Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 44.8 bits (101), Expect = 4e-04
Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++ E+ R+ L+ W D RL+++
Sbjct: 58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSL 117
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N D R+S NG V RL ++ M L
Sbjct: 118 DLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLK 177
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTCT + S
Sbjct: 178 NFPMDVQTCTMQLES 192
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +2
Query: 239 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 418
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 419 RA---RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
R+ NG++ RL IS M+L +P D C KFGS
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGS 192
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/146 (23%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 466
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDXWPNDMQTCTFKFGS 544
I+ M+L +P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/146 (23%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 466
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDXWPNDMQTCTFKFGS 544
I+ M+L +P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/146 (23%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 466
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDXWPNDMQTCTFKFGS 544
I+ M+L +P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/146 (23%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 466
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDXWPNDMQTCTFKFGS 544
I+ M+L +P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/146 (23%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
Frame = +2
Query: 128 SLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRHAN-IRESESTVRILADLQMNWIDK 295
++S ++D+LL YD P + V +++ + + E + + W D+
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 296 RLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALRA---RVSNNGSVSXIKRL 466
RL + S + ++W PD N + A + R+ NG++ RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 467 DISTPISMQLDXWPNDMQTCTFKFGS 544
I+ M+L +P D C KFGS
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGS 176
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +2
Query: 239 ESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYAL 418
E E T+ + + WIDKRL ++ + ++W PD N + + +
Sbjct: 90 EMEYTMDVF--FRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTA 147
Query: 419 RA---RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
R+ NG++ RL IS M+L +P D C KFGS
Sbjct: 148 PNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGS 192
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 7/135 (5%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 481
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDXWPNDMQTC 526
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/170 (22%), Positives = 68/170 (40%), Gaps = 7/170 (4%)
Frame = +2
Query: 56 LILFCYRFLLTCAIASAAECENATSLSLMIDSLLATYDRESPPD---SKIVVNLTLHLRH 226
L+ F + C S E N + + +D LL YD PD + V + + +
Sbjct: 12 LLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVAS 71
Query: 227 AN-IRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSSERLWRPDVVLLNAAATTA 403
+ + E + Q +W DKRLS++ + +++L PD LN +
Sbjct: 72 IDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLCVPDTYFLNDKKSFV 131
Query: 404 GDYALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
++ R+ +G+V R+ + M L +P D Q CT + S
Sbjct: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES 181
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 7/135 (5%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 481
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDXWPNDMQTC 526
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 42.3 bits (95), Expect = 0.002
Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 7/135 (5%)
Frame = +2
Query: 143 IDSLLATYDRESPPD-SKIVVNLTLHLRHANI---RESESTVRILADLQMNWIDKRLSWN 310
+D L+A Y R P VN+ L L A+I E+ + L +W D RLS+N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 311 AGEWGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTP 481
++LW PD ++NA + D + R+ +G + R+ +
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 482 ISMQLDXWPNDMQTC 526
M L +P D Q C
Sbjct: 164 CDMDLAKYPMDEQEC 178
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 41.5 bits (93), Expect = 0.004
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+V R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 41.5 bits (93), Expect = 0.004
Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 17/180 (9%)
Frame = +2
Query: 56 LILFCYRFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK-IVVN 205
L L+ + ++ ++A++ E E A S S +D L+ YD P+ K VN
Sbjct: 7 LRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVN 66
Query: 206 LTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDV 373
++ ++ +I E+ R+ L+ W D RL++N S + +W+PD+
Sbjct: 67 VSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDL 126
Query: 374 VLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
N + R+S NG+V R+ ++ M L +P D+QTC + S
Sbjct: 127 FFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.5 bits (93), Expect = 0.004
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+V R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.5 bits (93), Expect = 0.004
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+V R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia) protein.
Length = 449
Score = 41.5 bits (93), Expect = 0.004
Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 17/180 (9%)
Frame = +2
Query: 56 LILFCYRFLLTCAIASAAECENATSL------SLMIDSLLAT---YDRESPPDSK-IVVN 205
L L+ + ++ ++A++ E E A S S +D L+ YD P+ K VN
Sbjct: 7 LRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVN 66
Query: 206 LTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDV 373
++ ++ +I E+ R+ L+ W D RL++N S + +W+PD+
Sbjct: 67 VSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDL 126
Query: 374 VLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
N + R+S NG+V R+ ++ M L +P D+QTC + S
Sbjct: 127 FFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.5 bits (93), Expect = 0.004
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+V R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 41.5 bits (93), Expect = 0.004
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+V R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 41.5 bits (93), Expect = 0.004
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Frame = +2
Query: 110 ECENATSLSLM-IDSLLATYDRESPPD---SKIVVNLTLHLRH-ANIRESESTVRILADL 274
E + LSL ++L A Y++ P+ + + LTL + ++I ES L
Sbjct: 29 EVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYL 88
Query: 275 QMNWIDKRLSWNAGE-WGCSTWLVSSERLWRPDVVLLNAAATTAGDYALR---ARVSNNG 442
+ W+D+RL + + + LV E LW PD ++ + + + + R+ +NG
Sbjct: 89 RQRWMDQRLVFEGNKSFTLDARLV--EFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNG 146
Query: 443 SVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+V R+ + +M L +P D QTC + S
Sbjct: 147 TVLYALRITTTVACNMDLSKYPMDTQTCKLQLES 180
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 39.5 bits (88), Expect = 0.015
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 4/109 (3%)
Frame = +2
Query: 230 NIRESESTVRILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAG 406
+I E+ R+ L+ W D RL++N S + +W+PD+ N
Sbjct: 78 SIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFH 137
Query: 407 DYALR---ARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
+ R+S NG+V R+ ++ M L +P D+QTC + S
Sbjct: 138 EITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 186
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.1 bits (87), Expect = 0.020
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 39.1 bits (87), Expect = 0.020
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ ++I ++ R+ L+ W D RLS+
Sbjct: 17 YDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSL 76
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V RL + M L
Sbjct: 77 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLK 136
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTCT + S
Sbjct: 137 NFPMDIQTCTMQLES 151
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 38.3 bits (85), Expect = 0.034
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 38.3 bits (85), Expect = 0.034
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 38.3 bits (85), Expect = 0.034
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 8/135 (5%)
Frame = +2
Query: 164 YDRESPPDSK-IVVNLTLHL---RHANIRESESTVRILADLQMNWIDKRLSWNAGEWGCS 331
YD P+ K VN+T ++ +I E+ R+ L+ W D RL+++
Sbjct: 57 YDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSL 116
Query: 332 TWLVSS-ERLWRPDVVLLNAAATTAGDYALR---ARVSNNGSVSXIKRLDISTPISMQLD 499
S + +W+PD+ N + R+ NG+V RL ++ M L
Sbjct: 117 DLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLK 176
Query: 500 XWPNDMQTCTFKFGS 544
+P D+QTC + S
Sbjct: 177 NFPMDVQTCIMQLES 191
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 37.1 bits (82), Expect = 0.079
Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Frame = +2
Query: 257 RILADLQMNWIDKRLSWNAGEWGCSTWLVSS-ERLWRPDVVLLNAAATTAGDYALR---A 424
R+ L+ W D RL++N S + +W+PD+ N +
Sbjct: 4 RVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLL 63
Query: 425 RVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFKFGS 544
R+S NG+V R+ ++ M L +P D+QTC + S
Sbjct: 64 RISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES 103
>AB209359-1|BAD92596.1| 533|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 precursor variant
protein.
Length = 533
Score = 30.3 bits (65), Expect = 9.1
Identities = 17/63 (26%), Positives = 27/63 (42%)
Frame = +2
Query: 356 LWRPDVVLLNAAATTAGDYALRARVSNNGSVSXIKRLDISTPISMQLDXWPNDMQTCTFK 535
LW +A A + +A + ++G V + S+ + +P D Q CT K
Sbjct: 25 LWLCCCTFTSADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMK 84
Query: 536 FGS 544
FGS
Sbjct: 85 FGS 87
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,847,472
Number of Sequences: 237096
Number of extensions: 2098369
Number of successful extensions: 5213
Number of sequences better than 10.0: 158
Number of HSP's better than 10.0 without gapping: 4838
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5080
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10593928420
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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